go 6976 and sb 203580

go 6976 has been researched along with sb 203580 in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's14 (70.00)29.6817
2010's4 (20.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Caivano, M; Cohen, P; Davies, SP; Reddy, H1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Barnes, PJ; Giembycz, MA; Hellewell, PG; Lindsay, MA; Lynch, OT1
Akkerman, JW; Gorter, G; van Willigen, G1
Joe, E; Jou, I; Pyo, H; Ryu, J1
Barnes, PJ; Giembycz, MA; Lindsay, MA; Lynch, OT1
Deb, DK; Fish, EN; Kambhampati, S; Lekmine, F; Majchrzak, B; Platanias, LC; Rahman, A; Sassano, A; Uddin, S; Verma, A1
Chain, BM; Cho, JY; Katz, DR1
Akiyama, N; Hirabayashi, T; Murayama, T; Shimamura, K; Takashiro, Y1
Chun, JS; Jeon, HB; Lee, JH; Lee, SJ; Yoo, JS; Yoo, YJ1
Togo, T1
Cao, J; Cetrulo, CL; Kandere-Grzybowska, K; Kempuraj, D; Theoharides, TC1
Diao, F; Liu, S; Liu, Y; Ni, X; Xu, R; Zhu, X1
Kanai, T; Maruta, T; Miyazaki, S; Nemoto, T; Satoh, S; Wada, A; Yanagita, T; Yoshikawa, N1
Aoki, M; Hirose, E; Ishimaru, Y; Kawata, J; Matsmoto, T; Narahara, S; Ono, T; Sagara, K; Yamaguchi, Y1
Ameen, M; Arthur Ataam, J; Bharucha, N; Bruyneel, AAN; Diecke, S; Feyen, DAM; Furihata, T; Gavidia, AA; Karakikes, I; Kaur, B; Lim, EW; Martinez-Amador, N; Mercola, M; Metallo, CM; Monte, E; Nair, P; Perea-Gil, I; Seeger, T; Serrano, R; Snyder, MP; Termglinchan, V; Vadgama, N1

Other Studies

20 other study(ies) available for go 6976 and sb 203580

ArticleYear
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
    The Biochemical journal, 2000, Oct-01, Volume: 351, Issue:Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides

2000
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
'Outside-in' signalling mechanisms underlying CD11b/CD18-mediated NADPH oxidase activation in human adherent blood eosinophils.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Androstadienes; Carbazoles; CD18 Antigens; Cell Adhesion; Cell Count; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Humans; Imidazoles; Indoles; Isoenzymes; Macrophage-1 Antigen; Maleimides; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrazoles; Pyridines; Pyrimidines; Signal Transduction; src-Family Kinases; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin

1999
Thrombopoietin increases platelet sensitivity to alpha-thrombin via activation of the ERK2-cPLA2 pathway.
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:4

    Topics: Animals; Blood Platelets; Carbazoles; Cattle; Cytoplasmic Granules; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Group IV Phospholipases A2; Humans; Imidazoles; Indoles; Indomethacin; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Aggregation; Protein Kinase C; Protein Processing, Post-Translational; Pyridines; Serotonin; Serum Albumin, Bovine; Thrombin; Thrombopoietin; Thromboxane A2

2000
Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B.
    The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39

    Topics: Acetylcysteine; Animals; Carbazoles; Cells, Cultured; Cerebral Cortex; Enzyme Induction; Flavonoids; Imidazoles; Indoles; Maleimides; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Kinase C; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Thrombin

2000
Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Androstadienes; Animals; Antibodies; Carbazoles; CD18 Antigens; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Eosinophils; Flavonoids; Guinea Pigs; Imidazoles; Indoles; Integrin beta1; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Macrophage-1 Antigen; Male; Maleimides; Mitogen-Activated Protein Kinases; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Rats; src-Family Kinases; Stilbenes; Syk Kinase; Time Factors; Wortmannin

2001
Activation of protein kinase C delta by IFN-gamma.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Jul-01, Volume: 171, Issue:1

    Topics: Acetophenones; Benzopyrans; Carbazoles; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Indoles; Interferon gamma Receptor; Interferon-gamma; Isoenzymes; Mesylates; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Kinase C-delta; Pyridines; Pyrroles; Receptors, Interferon; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Tumor Cells, Cultured

2003
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells

2003
Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells.
    European journal of pharmacology, 2004, Feb-20, Volume: 486, Issue:2

    Topics: Acetophenones; Benzopyrans; Blotting, Western; Carbazoles; Cell Adhesion Molecules; Cells, Cultured; E-Selectin; Endothelium, Vascular; Estrenes; Histamine; Histamine Agonists; Humans; Imidazoles; Indoles; Intercellular Adhesion Molecule-1; Lysophospholipids; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; RNA, Messenger; Signal Transduction; Sphingosine; Type C Phospholipases; Umbilical Veins; Vascular Cell Adhesion Molecule-1

2004
Identification of proteins differentially expressed during chondrogenesis of mesenchymal cells.
    FEBS letters, 2004, Apr-09, Volume: 563, Issue:1-3

    Topics: Animals; Carbazoles; Cell Differentiation; Cells, Cultured; Chick Embryo; Chondrocytes; Chondrogenesis; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Extracellular Matrix; Flavonoids; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Imidazoles; Indoles; Mesoderm; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinases; Proteins; Proteome; Pyridines; Signal Transduction; Time Factors

2004
Long-term potentiation of wound-induced exocytosis and plasma membrane repair is dependent on cAMP-response element-mediated transcription via a protein kinase C- and p38 MAPK-dependent pathway.
    The Journal of biological chemistry, 2004, Oct-22, Volume: 279, Issue:43

    Topics: 3T3 Cells; Animals; Carbazoles; Cell Membrane; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Fibroblasts; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Image Processing, Computer-Assisted; Imidazoles; Indoles; Kinetics; Mice; Microscopy, Fluorescence; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Signal Transduction; Time Factors; Transfection; Wound Healing

2004
Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin.
    British journal of pharmacology, 2006, Volume: 148, Issue:2

    Topics: Carbazoles; Cell Line, Tumor; Cells, Cultured; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Indoles; Interleukin-1; Interleukin-6; Isoenzymes; Mast Cells; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Quercetin

2006
Lipopolysaccharide primes macrophages to increase nitric oxide production in response to Staphylococcus aureus.
    Immunology letters, 2007, Oct-15, Volume: 112, Issue:2

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Carbazoles; Cell Line; Cyclosporine; Humans; Imidazoles; Indoles; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Sepsis; Staphylococcus aureus

2007
Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK and p38.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: Animals; Calcium; Carbazoles; Cattle; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Cones; Humans; Imidazoles; Ion Channel Gating; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nicotine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-alpha; Pyridines; Receptors, Nicotinic; Sodium Channels; tau Proteins; Tetrodotoxin; Time Factors; Veratridine

2010
Mechanism of tissue factor production by monocytes stimulated with neutrophil elastase.
    Blood cells, molecules & diseases, 2015, Volume: 54, Issue:2

    Topics: Calcium Channel Blockers; Carbazoles; Enzyme Inhibitors; Estrenes; Flavonoids; Gallic Acid; Gene Expression Regulation; Humans; Imidazoles; Indoles; Leukocyte Elastase; Maleimides; Monocytes; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; RNA, Messenger; Signal Transduction; Thromboplastin; Type C Phospholipases

2015
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy.
    European heart journal, 2022, 09-21, Volume: 43, Issue:36

    Topics: Activating Transcription Factor 4; Adenosine Triphosphate; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cardiomyopathy, Dilated; Drug Evaluation, Preclinical; Glucose; Glycine; Humans; Imidazoles; Induced Pluripotent Stem Cells; Molecular Targeted Therapy; Mutation; Myocytes, Cardiac; Phosphoglycerate Dehydrogenase; Protein Kinase Inhibitors; Pyridines; Serine; Troponin T

2022