go 6976 has been researched along with ro 31-8220 in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (16.22) | 18.2507 |
| 2000's | 23 (62.16) | 29.6817 |
| 2010's | 7 (18.92) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Caivano, M; Cohen, P; Davies, SP; Reddy, H | 1 |
| Goekjian, P; Jochum, A; Jung, M; Kunick, C; Marshall, B; Meier, R; Saunders, L; Sippl, W; Trapp, J; Verdin, E | 1 |
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Harris, TE; Jones, PM; Persaud, SJ | 1 |
| Abdel-Latif, AA; Husain, S | 1 |
| MacGlashan, DW; Miura, K | 1 |
| Goekjian, PG; Jirousek, MR | 1 |
| Barnes, PJ; Giembycz, MA; Hellewell, PG; Lindsay, MA; Lynch, OT | 1 |
| Henrion, D; Lehoux, S; Lévy, BI; Loufrani, L; Tedgui, A | 1 |
| Garfinkel, MR; Littman, ED; Opara, EC; Pitchumoni, S | 1 |
| Akkerman, JW; Gorter, G; van Willigen, G | 1 |
| Joe, E; Jou, I; Pyo, H; Ryu, J | 1 |
| Hunziker, IP; Keller, HU; Niggli, V; Sordat, B; Sroka, J | 1 |
| Brautigan, DL; Eto, M; Kitazawa, T; Mukai, H; Ono, Y; Yazawa, M | 1 |
| Braileanu, GT; Hu, J; Mirando, MA | 1 |
| Chen, JS; Song, JG | 1 |
| Barnes, PJ; Giembycz, MA; Lindsay, MA; Lynch, OT | 1 |
| Davidson-Moncada, JK; Dekker, LV; Lopez-Lluch, G; Segal, AW | 1 |
| Fährmann, M; Kaufhold, M; Rieg, T; Seidler, U | 1 |
| Chen, YZ; Irie, A; Jotsuka, T; Masuda, M; Nishimura, Y; Tsukamoto, H | 1 |
| Cunningham, FM; Goode, NT; Greenaway, EC; Sepulveda, MF | 1 |
| Anel, A; Boyer, C; Buferne, M; Martínez-Lorenzo, MJ; Naval, J; Pardo, J; Schmitt-Verhulst, AM | 1 |
| Bahraoui, E; Bennasser, Y; Contreras, X | 1 |
| Avella, M; Cunningham, FM; Goode, NT; Greenaway, EC; Sepulveda, MF | 1 |
| Li, F; Shi, J; Song, J; Wang, D; Zhou, Y | 1 |
| Grybko, MJ; Pores-Fernando, AT; Wurth, GA; Zweifach, A | 1 |
| Namiki, H; Takahashi, H | 1 |
| Hori, M; Kanzaki, H; Nakajima, T; Nakamoto, T; Okada, H; Ozaki, H; Yasuda, K; Yasuhara, M | 1 |
| Altmann, F; Baer, AS; Ffrench-Constant, C; Franklin, RJ; Kang, SU; Kotter, MR; Lubec, G; Mitteregger, D; Syed, YA; Vig, R | 1 |
| Bien, MY; Chang, HM; Chen, BC; Chien, MH; Chiu, WT; Hong, CY; Hsu, MJ; Lin, CH; Sureshbabu, M; Tzeng, JI; Wang, JJ | 1 |
| Hong, JY; Kim, KE; Kim, KW; Lee, KE; Sohn, MH | 1 |
| Barthwal, MK; Bogra, J; Dikshit, M; Kohli, M; Kothari, N; Rana, M; Singh, A; Singh, V; Tiwari, RL; Verma, A | 1 |
| Ahmad, G; Bailey, TA; Band, H; Band, V; Bielecki, TA; George, M; Kelly, DL; Luan, H; Mohapatra, B; Natarajan, A; Raja, SM; Tom, E | 1 |
| Arias-Montaño, JA; Escamilla-Sánchez, J; García-Hernández, U; Montejo-López, W; Rivera-Ramírez, N | 1 |
1 review(s) available for go 6976 and ro 31-8220
| Article | Year |
|---|---|
Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development.
Topics: Azepines; Bryostatins; Carbazoles; Enzyme Inhibitors; Humans; Hydroxybenzoates; Indoles; Lactones; Macrolides; Maleimides; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Pyrroles; Signal Transduction; Thionucleotides | 1999 |
36 other study(ies) available for go 6976 and ro 31-8220
| Article | Year |
|---|---|
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides | 2000 |
Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.
Topics: Acetylation; Adenosine; Binding Sites; Cell Line, Tumor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Mimicry; Protein Kinase Inhibitors; Sirtuins; Structure-Activity Relationship; Tubulin | 2006 |
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Atypical isoforms of pKc and insulin secretion from pancreatic beta-cells: evidence using Gö 6976 and Ro 31-8220 as Pkc inhibitors.
Topics: Animals; Carbazoles; Enzyme Inhibitors; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1996 |
Role of protein kinase C alpha in endothelin-1 stimulation of cytosolic phospholipase A2 and arachidonic acid release in cultured cat iris sphincter smooth muscle cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cats; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Endothelin-1; Genistein; Indoles; Iris; Isoenzymes; Lipoprotein Lipase; Muscle, Smooth; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Kinase C-alpha | 1998 |
Expression of protein kinase C isozymes in human basophils: regulation by physiological and nonphysiological stimuli.
Topics: Antibodies, Anti-Idiotypic; Basophils; Biological Transport; Calcium; Carbazoles; Cell Membrane; Cells, Cultured; Enzyme Induction; Enzyme Inhibitors; Histamine Release; Humans; Indoles; Ionomycin; Ionophores; Isoenzymes; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
'Outside-in' signalling mechanisms underlying CD11b/CD18-mediated NADPH oxidase activation in human adherent blood eosinophils.
Topics: Androstadienes; Carbazoles; CD18 Antigens; Cell Adhesion; Cell Count; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Humans; Imidazoles; Indoles; Isoenzymes; Macrophage-1 Antigen; Maleimides; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrazoles; Pyridines; Pyrimidines; Signal Transduction; src-Family Kinases; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin | 1999 |
Stretch induces mitogen-activated protein kinase activation and myogenic tone through 2 distinct pathways.
Topics: Animals; Benzoquinones; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix; Flavonoids; Genistein; Indoles; Lactams, Macrocyclic; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Tonus; Protein Kinase C; Quinones; Rabbits; Rifabutin; Temperature; Vasoconstriction; Veins | 1999 |
Role of protein kinase C isoenzymes in fatty acid stimulation of insulin secretion.
Topics: Animals; Carbazoles; Enzyme Inhibitors; Fatty Acids; Female; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Linoleic Acid; Palmitic Acid; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction | 2000 |
Thrombopoietin increases platelet sensitivity to alpha-thrombin via activation of the ERK2-cPLA2 pathway.
Topics: Animals; Blood Platelets; Carbazoles; Cattle; Cytoplasmic Granules; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Group IV Phospholipases A2; Humans; Imidazoles; Indoles; Indomethacin; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Aggregation; Protein Kinase C; Protein Processing, Post-Translational; Pyridines; Serotonin; Serum Albumin, Bovine; Thrombin; Thrombopoietin; Thromboxane A2 | 2000 |
Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B.
Topics: Acetylcysteine; Animals; Carbazoles; Cells, Cultured; Cerebral Cortex; Enzyme Induction; Flavonoids; Imidazoles; Indoles; Maleimides; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Kinase C; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Thrombin | 2000 |
Protein kinase C isoforms involved in regulation of cell shape and locomotion of human fibrosarcoma HT1080 cells.
Topics: Carbazoles; Cell Membrane; Cell Movement; Cell Size; Cytosol; Enzyme Inhibitors; Fibrosarcoma; Humans; Indoles; Isoenzymes; Kinetics; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 2000 |
Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms.
Topics: Amides; Amino Acid Sequence; Animals; Aorta; Carbazoles; Chromatography; Chromatography, Affinity; Chromatography, Ion Exchange; Durapatite; Enzyme Activation; Enzyme Inhibitors; Histamine; In Vitro Techniques; Indoles; Isoenzymes; Kinetics; Maleimides; Molecular Sequence Data; Muscle Contraction; Muscle Proteins; Muscle Relaxants, Central; Muscle, Smooth, Vascular; Myelin Basic Protein; Myosin-Light-Chain Phosphatase; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Pyridines; Recombinant Proteins; Substrate Specificity; Swine; Vasoconstriction | 2001 |
Oxytocin stimulates prostaglandin F2alpha secretion from porcine endometrial cells through activation of calcium-dependent protein kinase C.
Topics: Animals; Calcium; Carbazoles; Dinoprost; Drug Synergism; Endometrium; Enzyme Activation; Enzyme Inhibitors; Female; Indoles; Inositol Phosphates; L-Lactate Dehydrogenase; Male; Oxytocin; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells.
Topics: Acetophenones; Benzopyrans; Bradykinin; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunoblotting; Indoles; Isoenzymes; Kinetics; Maleimides; Phospholipase D; Phospholipids; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils.
Topics: Androstadienes; Animals; Antibodies; Carbazoles; CD18 Antigens; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Eosinophils; Flavonoids; Guinea Pigs; Imidazoles; Indoles; Integrin beta1; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Macrophage-1 Antigen; Male; Maleimides; Mitogen-Activated Protein Kinases; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Rats; src-Family Kinases; Stilbenes; Syk Kinase; Time Factors; Wortmannin | 2001 |
Involvement of protein kinase D in Fc gamma-receptor activation of the NADPH oxidase in neutrophils.
Topics: Carbazoles; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Humans; Immunoglobulin G; Indoles; Maleimides; Microscopy, Fluorescence; NADPH Oxidases; Neutrophils; Oligonucleotides, Antisense; Oxygen; Oxygen Consumption; Phagocytosis; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, IgG; Recombinant Proteins; Signal Transduction; Staphylococcus aureus | 2002 |
Different actions of protein kinase C isoforms alpha and epsilon on gastric acid secretion.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Cells, Cultured; Enzyme Activators; Gastric Acid; In Vitro Techniques; Indoles; Male; Parietal Cells, Gastric; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Rabbits; Tetradecanoylphorbol Acetate | 2002 |
Unique T cell proliferation associated with PKCmu activation and impaired ZAP-70 phosphorylation in recognition of overexpressed HLA/partially agonistic peptide complexes.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Anion Exchange Protein 1, Erythrocyte; Antigen Presentation; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Carbazoles; Carrier Proteins; CD4-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Coculture Techniques; Enzyme Activation; Enzyme Inhibitors; HLA-DR4 Antigen; Humans; Indoles; Jurkat Cells; L Cells; Ligands; Lymphocyte Activation; Membrane Proteins; Mice; Molecular Sequence Data; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Recombinant Fusion Proteins; Signal Transduction; T-Lymphocyte Subsets; Transfection; ZAP-70 Protein-Tyrosine Kinase | 2003 |
Protein kinase C (PKC) isotype profile in eosinophils from ponies with sweet itch and role in histamine-induced eosinophil activation.
Topics: Animals; Blotting, Western; Carbazoles; Dermatitis, Allergic Contact; Enzyme Inhibitors; Eosinophils; Histamine; Horse Diseases; Horses; Indoles; Isoenzymes; Lymphocyte Activation; Male; Protein Kinase C; Staurosporine; Superoxides | 2003 |
Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.
Topics: Acetophenones; Androstadienes; Animals; Antibodies, Monoclonal; Benzopyrans; Carbazoles; Cell Degranulation; Cell Line; Chromones; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; Fas Ligand Protein; Humans; Indoles; Ionomycin; Isoenzymes; Jurkat Cells; Luciferases; Lymphocyte Activation; Membrane Glycoproteins; Mice; Morpholines; Perforin; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pore Forming Cytotoxic Proteins; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes, Cytotoxic; Transfection; Wortmannin | 2003 |
IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes.
Topics: Acetophenones; Benzopyrans; Carbazoles; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation; Gene Products, tat; HIV-1; Humans; Indoles; Interleukin-10; Maleimides; Monocytes; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Pyrones; tat Gene Products, Human Immunodeficiency Virus | 2004 |
The role of protein kinase C in regulating equine eosinophil adherence and superoxide production.
Topics: Analysis of Variance; Animals; Carbazoles; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophil Peroxidase; Eosinophils; Histamine; Horses; Indoles; Inhibitory Concentration 50; Interleukin-5; Plastics; Protein Kinase C; Protein Kinase C-delta; RNA Interference; Superoxides; Zymosan | 2005 |
Different roles of protein kinase C-betaI and -delta in the regulation of adipocyte differentiation.
Topics: 3T3-L1 Cells; Acetophenones; Adipocytes; Adipogenesis; Animals; Benzopyrans; Carbazoles; Cell Differentiation; Cell Membrane; Cell Proliferation; Chromans; Cytosol; Epidermal Growth Factor; Gene Expression; Genes, Dominant; Indoles; Mice; Mutant Proteins; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Protein Transport; Tetradecanoylphorbol Acetate; Thiazolidinediones; Transforming Growth Factor beta; Troglitazone | 2006 |
Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role.
Topics: Acetophenones; Benzopyrans; Calcium; Carbazoles; Cell Line, Tumor; Cell Membrane; Cytotoxicity, Immunologic; Exocytosis; Humans; Indoles; Mutation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase Inhibitors; Structure-Activity Relationship; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 2007 |
Mechanism of membrane redistribution of protein kinase C by its ATP-competitive inhibitors.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Carbazoles; Cell Membrane; Chlorocebus aethiops; COS Cells; Diglycerides; Estrenes; HeLa Cells; HL-60 Cells; Humans; Indoles; Maleimides; Membranes; Microscopy, Confocal; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Transport; Pyrrolidinones; Staurosporine | 2007 |
Role of protein kinase Cbeta in rhythmic contractions of human pregnant myometrium.
Topics: Adult; Carbazoles; Case-Control Studies; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Indoles; Labor, Obstetric; Maleimides; Myometrium; Obstetric Labor, Premature; Oxytocics; Oxytocin; Pregnancy; Pregnancy Trimester, Third; Protein Kinase C; Protein Kinase C beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stimulation, Chemical; Uterine Contraction | 2007 |
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Carbazoles; Cell Differentiation; Demyelinating Diseases; Electrophoresis, Polyacrylamide Gel; Indoles; Maleimides; Myelin Sheath; Nerve Regeneration; Oligodendroglia; Protein Kinase C-alpha; Proto-Oncogene Proteins c-fyn; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction; Stem Cells | 2009 |
Involvement of phosphatidylcholine-phospholipase C and protein kinase C in peptidoglycan-induced nuclear factor-kappaB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages.
Topics: Animals; Bridged-Ring Compounds; Carbazoles; Cell Line; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; Indoles; Macrophages; Mice; NF-kappa B; Norbornanes; Peptidoglycan; Phosphodiesterase Inhibitors; Phosphoinositide Phospholipase C; Protein Kinase C; Protein Kinase Inhibitors; Pyrrolidinones; Signal Transduction; Thiocarbamates; Thiones; Time Factors; Transfection; Type C Phospholipases | 2010 |
Chitinase induce the release of IL-8 in human airway epithelial cells, via Ca2+-dependent PKC and ERK pathways.
Topics: Blotting, Western; Butadienes; Caffeic Acids; Carbazoles; Cell Line, Tumor; Chitinases; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Indoles; Interleukin-8; Naphthalenes; NF-kappa B; Nitriles; Phenylethyl Alcohol; Protein Kinase C; Protein Kinase Inhibitors; Respiratory Mucosa; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2010 |
PKCδ-IRAK1 axis regulates oxidized LDL-induced IL-1β production in monocytes.
Topics: Acetophenones; Acetylcysteine; Adult; Benzofurans; Benzopyrans; Carbazoles; Female; Humans; Indoles; Interleukin-1 Receptor-Associated Kinases; Interleukin-1beta; Lipoproteins, LDL; Male; Middle Aged; Monocytes; Onium Compounds; Protein Kinase C-delta; Reactive Oxygen Species; Systemic Inflammatory Response Syndrome; THP-1 Cells; Toll-Like Receptors | 2014 |
A kinase inhibitor screen reveals protein kinase C-dependent endocytic recycling of ErbB2 in breast cancer cells.
Topics: Antineoplastic Agents; Benzoquinones; Breast Neoplasms; Carbazoles; Carcinogenesis; Cell Line, Tumor; Drug Screening Assays, Antitumor; Endocytosis; Endosomes; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Feedback, Physiological; Female; Humans; Indoles; Lactams, Macrocyclic; MAP Kinase Signaling System; Phosphorylation; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Transport; Receptor, ErbB-2 | 2014 |
Heterologous, PKC-Mediated Desensitization of Human Histamine H3 Receptors Expressed in CHO-K1 Cells.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Cell Membrane; CHO Cells; Colforsin; Cricetulus; Humans; Indoles; Phosphorylation; Protein Kinase C; Receptors, Histamine H3; Signal Transduction; Tetradecanoylphorbol Acetate | 2016 |