go 6976 and bryostatin 1

go 6976 has been researched along with bryostatin 1 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's7 (58.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marmé, D; May, WS; Qatsha, KA; Rudolph, C; Schächtele, C1
Ball, SG; Turner, NA; Vaughan, PF; Walker, JH1
Goode, N; Keenan, C; Pears, C1
Goekjian, PG; Jirousek, MR1
Bortner, CD; Cidlowski, JA; Gómez-Angelats, M1
Häussermann, S; Marks, F; Rennecke, J; Richter, KH; Stempka, L; Stöhr, M; Strand, S1
Clarke, H; Ginanni, N; Laughlin, KV; Mullin, JM; Pettit, GR; Smith, JB1
Cidlowski, JA; Gómez-Angelats, M1
González, MI; Kazanietz, MG; Robinson, MB1
Blois, JT; Chiles, TC; Mataraza, JM; Mecklenbraüker, I; Tarakhovsky, A1
Alexander, JS; Carpenter, AC1
Abdelnabi, R; Delang, L; Leyssen, P; Near, KE; Neyts, J; Staveness, D; Wender, PA1

Reviews

1 review(s) available for go 6976 and bryostatin 1

ArticleYear
Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development.
    Current medicinal chemistry, 1999, Volume: 6, Issue:9

    Topics: Azepines; Bryostatins; Carbazoles; Enzyme Inhibitors; Humans; Hydroxybenzoates; Indoles; Lactones; Macrolides; Maleimides; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Pyrroles; Signal Transduction; Thionucleotides

1999

Other Studies

11 other study(ies) available for go 6976 and bryostatin 1

ArticleYear
Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, May-15, Volume: 90, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bryostatins; Carbazoles; Enzyme Induction; HIV-1; Humans; In Vitro Techniques; Indoles; Isoquinolines; Lactones; Macrolides; Piperazines; Protein Kinase C; Retroviridae Proteins; RNA-Directed DNA Polymerase; RNA, Viral; Sulfonamides; Transcription, Genetic; Tumor Cells, Cultured; Virus Replication

1993
Phorbol ester-enhanced noradrenaline secretion correlates with the presence and activity of protein kinase C-alpha in human SH-SY5Y neuroblastoma cells.
    Journal of neurochemistry, 1996, Volume: 66, Issue:6

    Topics: Bryostatins; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Lactones; Macrolides; Maleimides; Mitogens; Neuroblastoma; Norepinephrine; Phorbol Esters; Protein Kinase C; Protein Kinase C-alpha; Time Factors; Tumor Cells, Cultured

1996
Isoform specificity of activators and inhibitors of protein kinase C gamma and delta.
    FEBS letters, 1997, Sep-22, Volume: 415, Issue:1

    Topics: Acetophenones; Alkaloids; Benzophenanthridines; Benzopyrans; Bryostatins; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoenzymes; Lactones; Macrolides; Maleimides; Naphthalenes; Phenanthridines; Protein Kinase C; Protein Kinase C-delta; Recombinant Proteins; Schizosaccharomyces; Sphingosine; Tetradecanoylphorbol Acetate; Transformation, Genetic

1997
Protein kinase C (PKC) inhibits fas receptor-induced apoptosis through modulation of the loss of K+ and cell shrinkage. A role for PKC upstream of caspases.
    The Journal of biological chemistry, 2000, Jun-30, Volume: 275, Issue:26

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Bryostatins; Carbazoles; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Concanavalin A; DNA; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Flow Cytometry; Humans; Indoles; Ions; Jurkat Cells; Lactones; Macrolides; Membrane Potentials; Mitochondria; Potassium; Protein Isoforms; Protein Kinase C; Rubidium Radioisotopes; Signal Transduction; Time Factors

2000
Biphasic effect of protein kinase C activators on spontaneous and glucocorticoid-induced apoptosis in primary mouse thymocytes.
    Biochimica et biophysica acta, 2000, Sep-20, Volume: 1497, Issue:3

    Topics: Animals; Apoptosis; Bryostatins; Carbazoles; Cells, Cultured; DNA Fragmentation; Down-Regulation; Enzyme Activation; Female; Fluocinolone Acetonide; Glucocorticoids; Immunoblotting; Indoles; Isoenzymes; Lactones; Macrolides; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymus Gland

2000
The transient increase of tight junction permeability induced by bryostatin 1 correlates with rapid downregulation of protein kinase C-alpha.
    Experimental cell research, 2000, Nov-25, Volume: 261, Issue:1

    Topics: Animals; Biological Transport; Bryostatins; Carbazoles; Cell Line; Cell Membrane Permeability; Cysteine Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Indoles; Isoenzymes; Kinetics; Lactones; Leupeptins; Macrolides; Mannitol; Membrane Potentials; Multienzyme Complexes; Polyethylene Glycols; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Tight Junctions

2000
Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis.
    The Journal of biological chemistry, 2001, Nov-30, Volume: 276, Issue:48

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Bryostatins; Carbazoles; Carcinogens; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Separation; Cytosol; Enzyme Inhibitors; fas Receptor; Fas-Associated Death Domain Protein; Flow Cytometry; Humans; Indoles; Jurkat Cells; Lactones; Macrolides; Mitogens; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Transport; Signal Transduction; Subcellular Fractions; Tetradecanoylphorbol Acetate

2001
Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes.
    Molecular pharmacology, 2002, Volume: 62, Issue:4

    Topics: Amino Acid Transport System X-AG; Animals; Bryostatins; Carbazoles; Carcinogens; Carrier Proteins; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Female; Glutamate Plasma Membrane Transport Proteins; Indoles; Lactones; Macrolides; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Symporters; Tetradecanoylphorbol Acetate

2002
B cell receptor-induced cAMP-response element-binding protein activation in B lymphocytes requires novel protein kinase Cdelta.
    The Journal of biological chemistry, 2004, Jul-16, Volume: 279, Issue:29

    Topics: Acetamides; Acetophenones; Animals; B-Lymphocytes; Benzopyrans; Binding Sites; Blotting, Western; Bryostatins; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Division; Cross-Linking Reagents; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Lactones; Macrolides; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Mitogens; Phosphorylation; Promoter Regions, Genetic; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Structure, Tertiary; Pyrans; Receptors, Antigen, B-Cell; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Signal Transduction; Spiro Compounds; Tetradecanoylphorbol Acetate; Time Factors

2004
Endothelial PKC delta activation attenuates neutrophil transendothelial migration.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2008, Volume: 57, Issue:5

    Topics: Antineoplastic Agents; Bryostatins; Carbazoles; Carcinogens; Cell Movement; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Focal Adhesion Kinase 1; Humans; Leukotriene B4; Neutrophils; Paxillin; Protein Kinase C-delta; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vinculin

2008
Comparative analysis of the anti-chikungunya virus activity of novel bryostatin analogs confirms the existence of a PKC-independent mechanism.
    Biochemical pharmacology, 2016, Nov-15, Volume: 120

    Topics: Acetylation; Animals; Antiviral Agents; Bryostatins; Carbazoles; Cell Line; Chikungunya virus; Chlorocebus aethiops; Drug Design; Drug Synergism; Gene Expression Regulation, Viral; Humans; Isoenzymes; Kinetics; Methylation; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Semliki forest virus; Sindbis Virus; Viral Proteins; Virus Replication

2016