glyoxylic acid and dichloroacetic acid

glyoxylic acid has been researched along with dichloroacetic acid in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's7 (63.64)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davidson, S; Mace, L; Shireman, RB1
Harwood, HJ; Schneider, M; Stacpoole, PW1
Harwood, HJ; Stacpoole, PW; Varnado, CE1
Evans, OB; Stacpoole, PW1
Schwille, PO; Sharma, V1
Bull, RJ; Gonzalez-Leon, A; Schultz, IR; Xu, G1
Cornett, R; Henderson, GN; James, MO; Stacpoole, PW; Yan, Z1
Anders, MW; Board, PG; Tong, Z1
Elfarra, AA; Krause, RJ; Lash, LH; Last, AR; Parker, JC1
Anders, MW; Anderson, WB; Board, PG; Tzeng, HF; Wempe, MF1
Cheung, J; Cornett, R; Henderson, GN; James, MO; Shroads, AL; Stacpoole, PW1

Other Studies

11 other study(ies) available for glyoxylic acid and dichloroacetic acid

ArticleYear
Effects of dichloroacetate and glyoxylate on low density lipoprotein uptake and on growth of cultured fibroblasts.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 175, Issue:4

    Topics: Acetates; Biological Transport; Cell Division; Cell Line; Cell Membrane; Dichloroacetic Acid; Fibroblasts; Glyoxylates; Humans; Kinetics; Lipoproteins, LDL; Receptors, Cell Surface; Receptors, LDL; Skin

1984
Measurement of human leukocyte microsomal HMG-CoA reductase activity.
    Journal of lipid research, 1984, Volume: 25, Issue:9

    Topics: Animals; Cholesterol; Dichloroacetic Acid; Glyoxylates; Granulocytes; Humans; Hydroxymethylglutaryl CoA Reductases; In Vitro Techniques; Leukocytes; Lymphocytes; Mevalonic Acid; Microsomes; Monocytes; NADP; Rats; Time Factors

1984
Regulation of rat liver hydroxymethylglutaryl coenzyme A reductase by a new class of noncompetitive inhibitors. Effects of dichloroacetate and related carboxylic acids on enzyme activity.
    The Journal of clinical investigation, 1983, Volume: 72, Issue:5

    Topics: Acetates; Animals; Cholesterol; Dichloroacetic Acid; Dose-Response Relationship, Drug; Glyoxylates; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Male; Microsomes, Liver; Oxalates; Oxalic Acid; Rats; Rats, Inbred Strains

1983
Prolonged hypolactatemia and increased total pyruvate dehydrogenase activity by dichloroacetate.
    Biochemical pharmacology, 1982, Apr-01, Volume: 31, Issue:7

    Topics: Acetates; Animals; Blood Glucose; Dichloroacetic Acid; Glyoxylates; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Oxalates; Oxalic Acid; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Time Factors

1982
Sulfite inhibits oxalate production from glycolate and glyoxylate in vitro and from dichloroacetate infused i.v. into male rats.
    Biochemical medicine and metabolic biology, 1993, Volume: 49, Issue:2

    Topics: Alcohol Oxidoreductases; Animals; Dichloroacetic Acid; Glycolates; Glyoxylates; L-Lactate Dehydrogenase; Liver; Male; Muscles; Oxalates; Oxalic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Sulfites

1993
Pharmacokinetics and metabolism of dichloroacetate in the F344 rat after prior administration in drinking water.
    Toxicology and applied pharmacology, 1997, Volume: 146, Issue:2

    Topics: Administration, Oral; Animals; Carbon Dioxide; Carbon Radioisotopes; Chromatography, Gas; Cytosol; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drinking; Fresh Water; Glycolates; Glyoxylates; In Vitro Techniques; Injections, Intravenous; Liver; Male; Oxalates; Rats; Rats, Inbred F344

1997
Glutathione-dependent conversion to glyoxylate, a major pathway of dichloroacetate biotransformation in hepatic cytosol from humans and rats, is reduced in dichloroacetate-treated rats.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:11

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cytosol; Dichloroacetic Acid; Gas Chromatography-Mass Spectrometry; Glutathione; Glyoxylates; Humans; In Vitro Techniques; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley

1997
Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid.
    The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2)

    Topics: Amino Acid Sequence; Animals; Carcinogens; Chromatography; Cytosol; Dichloroacetic Acid; Glutathione; Glutathione Transferase; Glyoxylates; Humans; Immunoblotting; Liver; Male; Molecular Sequence Data; Oxidation-Reduction; Rats; Rats, Inbred F344; Sequence Homology

1998
Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:8

    Topics: Acetates; Animals; Chloral Hydrate; Dichloroacetic Acid; Ethylene Chlorohydrin; Female; Glyoxylates; Humans; Kinetics; Male; Mice; Microsomes, Liver; NADP; Oxalates; Oxalic Acid; Rats; Rats, Inbred F344; Sex Factors; Solvents; Species Specificity; Trichloroethylene

1998
Glutathione transferase zeta-catalyzed biotransformation of deuterated dihaloacetic acids.
    Biochemical and biophysical research communications, 1999, Aug-11, Volume: 261, Issue:3

    Topics: Acetates; Animals; Biotransformation; Deuterium; Dichloroacetic Acid; Glutathione Transferase; Glyoxylates; Half-Life; Humans; Isoenzymes; Rats

1999
Inhibition of glutathione S-transferase zeta and tyrosine metabolism by dichloroacetate: a potential unifying mechanism for its altered biotransformation and toxicity.
    Biochemical and biophysical research communications, 1999, Sep-07, Volume: 262, Issue:3

    Topics: Animals; Biotransformation; Cytosol; Dichloroacetic Acid; Feedback; Glutathione Transferase; Glyoxylates; Humans; Isoenzymes; Kinetics; Liver; Maleates; Rats; Tyrosine

1999