Page last updated: 2024-08-18

glyoxal and lysine

glyoxal has been researched along with lysine in 85 studies

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-19908 (9.41)18.7374
1990's15 (17.65)18.2507
2000's20 (23.53)29.6817
2010's25 (29.41)24.3611
2020's17 (20.00)2.80

Authors

AuthorsStudies
Hashimoto, J; Takahashi, K1
Busby, TF; Gan, JC1
Kang, EP; Triantaphyllopoulos, DC1
Cox, RW; Grant, RA; Kent, CM1
Cohen, AB1
Jörnvall, H; Rasched, I; Sund, H1
Ashes, JR; Mangan, JL; Sidhu, GS1
Fox, PF; Shalabi, SI1
Baynes, JW; Bichler, J; Reddy, S; Thorpe, SR; Wells-Knecht, KJ1
Glomb, MA; Monnier, VM1
Baynes, JW; Litchfield, JE; Thorpe, SR; Wells-Knecht, KJ; Zyzak, DV1
Bazaes, S; Cardemil, E; Goldie, H; Jabalquinto, AM; Silva, R1
Baynes, JW; Fu, MX; Jenkins, AJ; Lyons, TJ; Requena, JR; Thorpe, SR1
Beisswenger, P; Brownlee, M; Giardino, I; Onorato, J; Shinohara, M; Thornalley, PJ; Thorpe, SR1
Baynes, JW; Brinkmann Frye, E; Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J1
Baynes, JW; Degenhardt, TP; Frye, EB; Thorpe, SR1
Kurokawa, K; Mitsuma, T; Miyata, T; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Yasuda, Y1
Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S1
Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J1
Fehrenbach, H; Funk, RH; Hofer, A; Kasper, M; Münch, G; Niwa, T; Pehlke, K; Schinzel, R; Wilsch-Bräuninger, M; Witt, M1
Langborg, A; Minhas, HS; Thornalley, PJ1
Klaiber, RG; Lederer, MO1
Uchida, K1
Bucala, R; Kameda, Y; Koike, T; Makita, Z; Suzuki, T; Takeuchi, M1
Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C1
Chellan, P; Duve, Y; Glomb, MA; Jiang, CL; Madhun, Z; Nagaraj, RH; Sady, C1
Clark, BF; Rattan, SI; Siboska, GE; Verbeke, P1
Goffin, E; Inagi, R; Ishibashi, Y; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; Van Ypersele De Strihou, C; Yoshino, A1
Fehrenbach, H; Funk, RH; Kasper, M; Kuhnt, AK; Roehlecke, C; Werner, C1
Biemel, KM; Bühler, HP; Lederer, MO; Reihl, O1
Glomb, MA; Pfahler, C1
Hayase, F; Hayashi, MC; Horiuchi, S; Kinae, N; Masuda, S; Nagai, R; Unno, Y1
Funk, RH; Geffarth, R; Kasper, M; Reber, F; Reichenbach, A; Schleicher, ED; Siegner, A1
Aimoto, S; Kawakami, T; Murata, M; Niwa, S; Oishi, T; Sasaki, T; Yamada, H1
Cervantes-Laurean, D; Jacobson, EL; Jacobson, MK; Roberts, MJ1
Horiuchi, S; Kawaguchi, M; Kobayashi, M; Shibata, N1
Lapolla, A; Ragazzi, E; Reitano, R; Sartore, G; Seraglia, R; Traldi, P1
Faridmoayer, A; Scaman, CH1
Funk, RH; Knels, L; Kniep, EM; Ozkucur, N; Reber, F; Roehlecke, C; Steinberg, A1
Fujiwara, Y; Mera, K; Nagai, R; Otagiri, M; Sakata, N1
Henle, T; Mende, S; Schwarzenbolz, U1
Blatt, T; Grune, T; Kueper, T; Lenz, H; Muhr, GM; Stäb, F; Wenck, H; Wittern, KP1
Glomb, MA; Gobert, J1
Field, MJ; Moosavi-Movahedi, AA; Nasiri, R; Zahedi, M1
Han, L; Li, B; Li, L; Li, Y; Liu, G; Xu, Z; Zhao, D1
Brimble, MA; Cooper, GJ; Harris, PW; Kamalov, M1
Barrow, M; Canelon, IR; Duque-Daza, CA; Lopez-Clavijo, AF; O'Connor, PB; Soulby, A1
Bui, LC; Dairou, J; Lamouri, A; Leger, T; Mihoub, M; Richarme, G1
Frau, J; Hernández-Laguna, A; Muñoz, F; Ortega-Castro, J; Solís-Calero, C1
André-Frei, V; Bechetoille, N; Berthod, F; Cadau, S; Leoty-Okombi, S; Pain, S1
Abdallah, J; Dairou, J; Gontero, B; Mihoub, M; Richarme, G1
Cheah, PS; Lee, KH; Lim, CK; Ng, YP; Toh, MS1
Huang, J; Ou, J; Ou, S; Wang, M1
Liu, G; Lu, Y; Lv, L; Sang, S; Xia, Q; Zheng, T1
Morales, FJ; Navarro, M1
Banerjee, S1
Hans, J; Holik, AK; Kretschy, N; Ley, JP; Lieder, B; Somoza, MM; Somoza, V1
Abdallah, J; Mihoub, M; Richarme, G1
Afsar, M; Al-Bagmi, MS; Bano, B; Bhat, SA; Bhat, WF; Khan, MS1
Ahmed, N; Brison, D; Carroll, M; McNeil, L; Murgatroyd, C; Nevin, C1
Holik, AK; Hölz, K; Somoza, MM; Somoza, V; Stöger, V1
Glomb, MA; Klaus, A; Rau, R1
Fei, X; Luo, F1
Lund, MN; Olsen, K; Poojary, MM; Ray, CA; Zhang, W1
Chen, J; Gao, D; He, J; He, Z; Jiao, Y; Qin, F; Xie, M; Zeng, M1
Broers, NJH; Canaud, B; Christiaans, MHL; Cornelis, T; Gauly, A; Hermans, MMH; Konings, CJAM; Kooman, JP; Martens, RJH; Schalkwijk, CG; Scheijen, JLJM; Stifft, F; van der Sande, FM; Wirtz, JJJM1
Chen, Y; Guo, Z; Lan, T; Li, Z; Liu, Y; Qin, W; Wang, C1
Liu, H; Wang, Y; Zhang, D1
Carganico, S; Gallo, A; Lapolla, A; Nuti, F; Papini, AM; Piarulli, F; Real-Fernandez, F; Rentier, C; Rossi, G; Rovero, P; Traldi, P1
Chern, C; Deo, P; Peake, B; Tan, SY1
Dong, L; Wang, JP; Wang, S; Wang, SJ; Zhuang, Y1
Bast, A; Opperhuizen, A; van der Lugt, T; van Leeuwen, S; Venema, K; Vrolijk, MF1
Eggen, MD; Glomb, MA1
Baldensperger, T; Dau, T; Di Sanzo, S; Glomb, MA; Heller, R; Henning, C; Kirkpatrick, JM; Leheis, A; Marx, C; Ori, A; Parca, L; Rändler, TL; Spengler, K; Wang, ZQ1
Glomb, MA; Rau, R1
Baskal, S; Tsikas, D1
Li, H; Wang, M; Wu, Z; Yu, J; Yuan, X; Zheng, Y1
Akıllıoğlu, HG; Chatterton, DEW; Lund, MN1
Eggen, MD; Glomb, MA; Merboth, P; Neukirchner, H1
Arabi, SH; Glomb, MA; Henning, C; Hinderberger, D; Volmer, J1
Ha, SK; Jeong, YJ; Kang, J; Lee, HH; Lee, KW1
Ho, CT; Huang, SF; Hung, WL; Liao, KW; Lin, YY1
Jiang, Y; Jie, RQD; Li, C; Li, H; Li, JX; Yu, J; Zhang, Y; Zhao, Y; Zulewska, J1
Li, J; Sun, X; Yan, S1
Chen, J; Hao, S; Li, M; Li, N; Liu, H; Lu, Z; Quan, W; Wu, X; Xie, D; Xu, H1

Reviews

1 review(s) available for glyoxal and lysine

ArticleYear
Current status of acrolein as a lipid peroxidation product.
    Trends in cardiovascular medicine, 1999, Volume: 9, Issue:5

    Topics: Acrolein; Air Pollutants; Aldehydes; Alzheimer Disease; Arteriosclerosis; Cross-Linking Reagents; Fatty Acids, Unsaturated; Glyoxal; Humans; Lipid Peroxidation; Lipid Peroxides; Lysine; Malondialdehyde; Oxidative Stress

1999

Trials

2 trial(s) available for glyoxal and lysine

ArticleYear
Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids.
    Kidney international, 2000, Volume: 58, Issue:6

    Topics: Aged; Amino Acids; Arginine; Deoxyglucose; Dialysis Solutions; Female; Filtration; Glucans; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Icodextrin; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis; Peritoneum; Pyruvaldehyde; Sterilization; Time Factors

2000
Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study.
    PloS one, 2019, Volume: 14, Issue:8

    Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus; Endothelium, Vascular; Female; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Ornithine; Renal Dialysis

2019

Other Studies

82 other study(ies) available for glyoxal and lysine

ArticleYear
Chemical modifications of ribonuclease U1.
    Journal of biochemistry, 1977, Volume: 81, Issue:4

    Topics: Amino Acids; Arginine; Binding Sites; Citraconic Anhydrides; Glutamates; Glyoxal; Guanine Nucleotides; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Iodoacetates; Lysine; Protein Binding; Ribonuclease T1; Ribonucleases

1977
Chemical modifications of lysyl and arginyl residues of human plasma alpha1-antitrypsin.
    Archives of biochemistry and biophysics, 1976, Volume: 177, Issue:2

    Topics: alpha 1-Antitrypsin; Arginine; Binding Sites; Chymotrypsin; Glyoxal; Histidine; Humans; Immunodiffusion; Ketones; Kinetics; Lysine; Protein Binding

1976
Fibrin digestion by thrombin: the significance of the arginyl and lysyl bonds.
    Thrombosis research, 1977, Volume: 11, Issue:3

    Topics: Arginine; Blood Coagulation; Dialysis; Fibrin; Fibrinogen; Glyoxal; Humans; Lysine; Peptides; Spectrum Analysis; Thrombin

1977
An electron-microscope study of the reaction of collagen with some monoaldehydes and bifunctional aldehydes.
    Journal of cell science, 1973, Volume: 12, Issue:3

    Topics: Acetaldehyde; Aldehydes; Animals; Arginine; Benzaldehydes; Chemical Phenomena; Chemistry; Collagen; Formaldehyde; Glutaral; Glyoxal; Hot Temperature; Lysine; Microscopy, Electron; Phosphotungstic Acid; Rats; Solubility; Staining and Labeling; Tail; Tendons; Tyrosine

1973
Mechanism of action of alpha-1-antitrypsin.
    The Journal of biological chemistry, 1973, Oct-25, Volume: 248, Issue:20

    Topics: alpha 1-Antitrypsin; Amino Acids; Anilides; Arginine; Aspartic Acid; Benzoates; Binding Sites; Binding, Competitive; Cholinesterase Inhibitors; Chymotrypsin; Fibrinolysin; Glyoxal; Histidine; Isoflurophate; Leucine; Lysine; Nitro Compounds; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Serine; Structure-Activity Relationship; Subtilisins; Thrombin; Trypsin Inhibitors

1973
Studies of glutamate dehydrogenase. Identification of an amino group involved in the substrate binding.
    European journal of biochemistry, 1974, Feb-01, Volume: 41, Issue:3

    Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Borohydrides; Cattle; Electrophoresis, Paper; Glutamate Dehydrogenase; Glyoxal; Iodoacetates; Ketoglutaric Acids; Liver; Lysine; Peptide Fragments; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Salicylates; Tritium; Trypsin

1974
Nutritional availability of amino acids from protein cross-linked to protect against degradation in the rumen.
    The British journal of nutrition, 1984, Volume: 52, Issue:2

    Topics: Amino Acids; Animals; Caseins; Dietary Proteins; Formaldehyde; Glutaral; Glyoxal; Goats; Intestinal Absorption; Leucine; Lysine; Milk Proteins; Nutritive Value; Rumen; Sheep; Tyrosine

1984
Heat stability of milk: influence of modification of lysine and arginine on the heat stability-pH profile.
    The Journal of dairy research, 1982, Volume: 49, Issue:4

    Topics: Acetic Anhydrides; Aldehydes; Animals; Arginine; Butanones; Cattle; Cyclohexanes; Cyclohexanones; Dansyl Compounds; Diacetyl; Glyoxal; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Methylurea Compounds; Milk

1982
N epsilon-(carboxymethyl)lysine is a dominant advanced glycation end product (AGE) antigen in tissue proteins.
    Biochemistry, 1995, Aug-29, Volume: 34, Issue:34

    Topics: Aging; Antigens; Chromatography, Gel; Crystallins; Enzyme-Linked Immunosorbent Assay; Fructose; Glucose; Glycation End Products, Advanced; Glyoxal; Humans; Kinetics; Lysine; Maillard Reaction; Serum Albumin, Bovine

1995
Mechanism of protein modification by glyoxal and glycolaldehyde, reactive intermediates of the Maillard reaction.
    The Journal of biological chemistry, 1995, Apr-28, Volume: 270, Issue:17

    Topics: Acetaldehyde; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Gas Chromatography-Mass Spectrometry; Glyoxal; Lysine; Maillard Reaction; Oxidation-Reduction; Proteins

1995
Mechanism of autoxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose.
    Biochemistry, 1995, Mar-21, Volume: 34, Issue:11

    Topics: Arabinose; Glucose; Glycosylation; Glyoxal; Ketoses; Kinetics; Lysine; Oxidation-Reduction; Proteins

1995
Reactivity of cysteinyl, arginyl, and lysyl residues of Escherichia coli phosphoenolpyruvate carboxykinase against group-specific chemical reagents.
    Journal of protein chemistry, 1993, Volume: 12, Issue:5

    Topics: Arginine; Binding Sites; Cysteine; Diacetyl; Escherichia coli; Glyoxal; Kinetics; Lysine; Phosphoenolpyruvate Carboxykinase (GTP); Pyrenes; Pyridoxal Phosphate; Sulfhydryl Reagents

1993
The advanced glycation end product, Nepsilon-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions.
    The Journal of biological chemistry, 1996, Apr-26, Volume: 271, Issue:17

    Topics: Arachidonic Acid; Copper; Glycation End Products, Advanced; Glyoxal; Humans; Lipid Peroxides; Lipoproteins, LDL; Lysine; Oxidation-Reduction

1996
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.
    The Journal of clinical investigation, 1998, Mar-01, Volume: 101, Issue:5

    Topics: Acetone; Aldehydes; Animals; Cattle; Endocytosis; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Glycation End Products, Advanced; Glyoxal; Hyperglycemia; Ketones; Lactic Acid; Lactoylglutathione Lyase; Lysine; Pyruvaldehyde; Transfection; Tumor Cells, Cultured

1998
Imidazolium crosslinks derived from reaction of lysine with glyoxal and methylglyoxal are increased in serum proteins of uremic patients: evidence for increased oxidative stress in uremia.
    FEBS letters, 1998, May-15, Volume: 427, Issue:3

    Topics: Cross-Linking Reagents; Female; Glyoxal; Humans; Imidazoles; Kidney Failure, Chronic; Lysine; Male; Mass Spectrometry; Middle Aged; Oxidative Stress; Pyruvaldehyde; Uremia

1998
Role of the Maillard reaction in aging of tissue proteins. Advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins.
    The Journal of biological chemistry, 1998, Jul-24, Volume: 273, Issue:30

    Topics: Aging; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Crystallins; Dimerization; Glycation End Products, Advanced; Glyoxal; Humans; Imidazoles; In Vitro Techniques; Lysine; Maillard Reaction; Pyruvaldehyde; Ribonucleases

1998
Accelerated formation of N epsilon-(carboxymethyl) lysine, an advanced glycation end product, by glyoxal and 3-deoxyglucosone in cultured rat sensory neurons.
    Biochemical and biophysical research communications, 1998, Jul-09, Volume: 248, Issue:1

    Topics: Animals; Apoptosis; Culture Techniques; Deoxyglucose; Dose-Response Relationship, Drug; Ganglia, Spinal; Glycation End Products, Advanced; Glyoxal; Guanidines; Lysine; Neurons, Afferent; Rats; Rats, Sprague-Dawley

1998
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia

1998
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
    Biochemical and biophysical research communications, 1999, Mar-05, Volume: 256, Issue:1

    Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia

1999
Experimental induction of AGEs in fetal L132 lung cells changes the level of intracellular cathepsin D.
    Biochemical and biophysical research communications, 1999, Jul-22, Volume: 261, Issue:1

    Topics: Antibodies; Cathepsin D; Cell Line; Cell Membrane; Cell Nucleus; Cell Size; Cytosol; Epithelial Cells; Gene Expression Regulation, Enzymologic; Glycation End Products, Advanced; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lung; Lysine; Lysosomes; Microscopy, Electron; Pulmonary Fibrosis; RNA, Messenger

1999
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.
    The Biochemical journal, 1999, Nov-15, Volume: 344 Pt 1

    Topics: Deoxyglucose; Fructosamine; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; In Vitro Techniques; Lysine; Proteins; Pyruvaldehyde; Schiff Bases; Serum Albumin

1999
Cross-linking of proteins by Maillard processes: characterization and detection of lysine-arginine cross-links derived from glyoxal and methylglyoxal.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:11

    Topics: Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Glyoxal; Imidazoles; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Pyruvaldehyde; Serum Albumin, Bovine

1999
Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo.
    Molecular medicine (Cambridge, Mass.), 2000, Volume: 6, Issue:2

    Topics: Animals; Antibodies; Cattle; Chromatography, Affinity; Cross Reactions; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glyceraldehyde; Glyoxal; Humans; Immunoblotting; Kidney Failure, Chronic; Lysine; Maillard Reaction; Oxidation-Reduction; Pyruvaldehyde; Rabbits; Renal Dialysis

2000
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:9

    Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines

2000
Maillard reactions by alpha-oxoaldehydes: detection of glyoxal-modified proteins.
    Biochimica et biophysica acta, 2000, Sep-29, Volume: 1481, Issue:2

    Topics: Aged; Aging; Antibodies; Cataract; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Proteins; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human

2000
Kinetin inhibits protein oxidation and glycoxidation in vitro.
    Biochemical and biophysical research communications, 2000, Oct-05, Volume: 276, Issue:3

    Topics: Adenine; Animals; Arabinose; Arginine; Cattle; Glycation End Products, Advanced; Glyoxal; Kinetin; Lysine; Oxidants; Oxidation-Reduction; Protein Denaturation; Reactive Oxygen Species; Ribose; Serum Albumin; Time Factors

2000
Resistance of L132 lung cell clusters to glyoxal-induced apoptosis.
    Histochemistry and cell biology, 2000, Volume: 114, Issue:4

    Topics: Anoikis; Apoptosis; Caspase 3; Caspases; Cell Line; Dose-Response Relationship, Drug; Drug Resistance; Epithelial Cells; Glycation End Products, Advanced; Glyoxal; Humans; Hyaluronan Receptors; Integrin beta1; Lung; Lysine; Spheroids, Cellular

2000
Identification and quantitative evaluation of the lysine-arginine crosslinks GODIC, MODIC, DODIC, and glucosepan in foods.
    Die Nahrung, 2001, Volume: 45, Issue:3

    Topics: Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Food Analysis; Food Handling; Gas Chromatography-Mass Spectrometry; Glyoxal; Imidazoles; Lysine; Maillard Reaction

2001
Amides are novel protein modifications formed by physiological sugars.
    The Journal of biological chemistry, 2001, Nov-09, Volume: 276, Issue:45

    Topics: Amides; Carbohydrate Metabolism; Glycation End Products, Advanced; Glyoxal; Lysine; Maillard Reaction; Proteins

2001
Peroxynitrite induces formation of N( epsilon )-(carboxymethyl) lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite.
    Diabetes, 2002, Volume: 51, Issue:9

    Topics: 2-Naphthylamine; Aldehydes; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glucose; Glyoxal; Guanidines; Ketoses; Lysine; Mice; Mice, Inbred BALB C; Peroxynitrous Acid; Serum Albumin; Tyrosine

2002
Graded sensitiveness of the various retinal neuron populations on the glyoxal-mediated formation of advanced glycation end products and ways of protection.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2003, Volume: 241, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Dose-Response Relationship, Drug; Female; Glycation End Products, Advanced; Glyoxal; Guanidines; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lysine; Male; Neurons; Niacinamide; Organ Culture Techniques; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retina; Thioctic Acid; Vanadates

2003
Intact glycation end products containing carboxymethyl-lysine and glyoxal lysine dimer obtained from synthetic collagen model peptide.
    Bioorganic & medicinal chemistry letters, 2004, Nov-15, Volume: 14, Issue:22

    Topics: Amino Acid Sequence; Collagen Type I; Dimerization; Glycation End Products, Advanced; Glyoxal; Humans; Lysine; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Protein Structure, Tertiary

2004
Nuclear proteasome activation and degradation of carboxymethylated histones in human keratinocytes following glyoxal treatment.
    Free radical biology & medicine, 2005, Mar-15, Volume: 38, Issue:6

    Topics: Blotting, Western; Cell Line; Cell Nucleus; Cell Proliferation; Chromatography, High Pressure Liquid; Cycloheximide; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Glycols; Glyoxal; Histones; Humans; Keratinocytes; Lysine; Methylation; Models, Biological; Oxidative Stress; Oxygen; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Time Factors

2005
Glyoxal inactivates glutamate transporter-1 in cultured rat astrocytes.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2005, Volume: 25, Issue:1

    Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Glutamic Acid; Glyoxal; Immunoblotting; Immunohistochemistry; Lysine; Rats

2005
Evaluation of advanced glycation end products and carbonyl compounds in patients with different conditions of oxidative stress.
    Molecular nutrition & food research, 2005, Volume: 49, Issue:7

    Topics: Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dialysis Solutions; Glycated Hemoglobin; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Oxidative Stress; Peritoneal Dialysis; Pyruvaldehyde

2005
Binding residues and catalytic domain of soluble Saccharomyces cerevisiae processing alpha-glucosidase I.
    Glycobiology, 2005, Volume: 15, Issue:12

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Amino Acid Sequence; Binding Sites; Bromosuccinimide; Catalysis; Catalytic Domain; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation, Fungal; Glycoside Hydrolases; Glycosylation; Glyoxal; Histidine; Hydrolysis; Lysine; Molecular Sequence Data; Peptides; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Temperature; Tetranitromethane; Time Factors; Trisaccharides; Trypsin; Tryptophan; Tyrosine

2005
Inhibition of apoptosis and reduction of intracellular pH decrease in retinal neural cell cultures by a blocker of carbonic anhydrase.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:3

    Topics: Animals; Annexin A5; Apoptosis; Carbonic Anhydrase Inhibitors; Caspase 3; Caspases; Cell Culture Techniques; Cell Survival; Flow Cytometry; Glyoxal; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Situ Nick-End Labeling; Lysine; Neurons; Neuroprotective Agents; Pyruvaldehyde; Rats; Reactive Oxygen Species; Retina; Sulfonamides; Thiophenes

2006
Immunological detection of N omega-(Carboxymethyl)arginine by a specific antibody.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Antibodies, Monoclonal; Antibody Specificity; Arginine; Biomarkers; Glucose; Glycation End Products, Advanced; Glyoxal; Lysine

2008
Model studies on protein glycation: influence of cysteine on the reactivity of arginine and lysine residues toward glyoxal.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Arginine; Chromatography, High Pressure Liquid; Cysteine; Glycosylation; Glyoxal; Kinetics; Lysine; Mass Spectrometry; Models, Molecular

2008
Modification of vimentin: a general mechanism of nonenzymatic glycation in human skin.
    Annals of the New York Academy of Sciences, 2008, Volume: 1126

    Topics: Arginine; Blotting, Western; Cells, Cultured; Face; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Norleucine; Pyrroles; Pyruvaldehyde; Skin; Vimentin

2008
Degradation of glucose: reinvestigation of reactive alpha-Dicarbonyl compounds.
    Journal of agricultural and food chemistry, 2009, Sep-23, Volume: 57, Issue:18

    Topics: Deoxyglucose; Glucose; Glyoxal; Ketoses; Lysine; Maillard Reaction; Pentanes; Phenylenediamines; Quinoxalines

2009
Comparative DFT study to determine if α-oxoaldehydes are precursors for pentosidine formation.
    The journal of physical chemistry. A, 2012, Mar-22, Volume: 116, Issue:11

    Topics: Arginine; Glycosylation; Glyoxal; Imidazoles; Kinetics; Lysine; Molecular Structure; Pyruvaldehyde; Quantum Theory; Schiff Bases; Thermodynamics; Water

2012
Hydroxyl radical induced by lipid in Maillard reaction model system promotes diet-derived N(ε)-carboxymethyllysine formation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 60

    Topics: Chromatography, High Pressure Liquid; Diet; Food Handling; Glyoxal; Hydroxyl Radical; Linoleic Acid; Lipid Metabolism; Lysine; Maillard Reaction; Models, Biological; Oleic Acid; Triolein

2013
Site-specific cross-linking of collagen peptides by lysyl advanced glycation endproducts.
    Chemical communications (Cambridge, England), 2014, May-18, Volume: 50, Issue:38

    Topics: Chromatography, High Pressure Liquid; Circular Dichroism; Collagen; Dimerization; Glycation End Products, Advanced; Glyoxal; Lysine; Pyruvaldehyde; Trypsin

2014
Unexpected crosslinking and diglycation as advanced glycation end-products from glyoxal.
    Journal of the American Society for Mass Spectrometry, 2014, Volume: 25, Issue:12

    Topics: Amino Acid Sequence; Cross-Linking Reagents; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Mass Spectrometry; Peptides

2014
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residues.
    The Journal of biological chemistry, 2015, Jan-16, Volume: 290, Issue:3

    Topics: Acetylcysteine; Albumins; Apoptosis; Arginine; Aspartate Aminotransferases; Catalysis; Cell Survival; Cysteine; Escherichia coli; Fructose-Bisphosphate Aldolase; Glucose; Glycolates; Glyoxal; Humans; Intracellular Signaling Peptides and Proteins; Lactates; Lysine; Mass Spectrometry; Oncogene Proteins; Oxidative Stress; Parkinsonian Disorders; Protein Deglycase DJ-1; Pyruvaldehyde

2015
A DFT study of the carboxymethyl-phosphatidylethanolamine formation from glyoxal and phosphatidylethanolamine surface. Comparison with the formation of N(ε)-(carboxymethyl)lysine from glyoxal and L-lysine.
    Physical chemistry chemical physics : PCCP, 2015, Mar-28, Volume: 17, Issue:12

    Topics: Glycation End Products, Advanced; Glyoxal; Hydrogen Bonding; Lysine; Models, Molecular; Phosphatidylethanolamines; Thermodynamics

2015
In vitro glycation of an endothelialized and innervated tissue-engineered skin to screen anti-AGE molecules.
    Biomaterials, 2015, Volume: 51

    Topics: Animals; Capillaries; Cattle; Cell Differentiation; Cells, Cultured; Collagen; Cytoskeleton; Dermis; Endothelial Cells; Fibroblasts; Filaggrin Proteins; Glycation End Products, Advanced; Glycosylation; Glyoxal; Guanidines; Humans; Keratinocytes; Lysine; Mice; Neurons; Protective Agents; Skin; Thiazoles; Tissue Engineering

2015
The DJ-1 superfamily member Hsp31 repairs proteins from glycation by methylglyoxal and glyoxal.
    Biochemical and biophysical research communications, 2015, Aug-07, Volume: 463, Issue:4

    Topics: Arginine; Cysteine; Escherichia coli Proteins; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Glyoxal; Lysine; Molecular Chaperones; Pyruvaldehyde; Schiff Bases

2015
Molecular characterization of glycation-associated skin ageing: an alternative skin model to study in vitro antiglycation activity of topical cosmeceutical and pharmaceutical formulations.
    The British journal of dermatology, 2017, Volume: 176, Issue:1

    Topics: Administration, Cutaneous; Cells, Cultured; Cosmeceuticals; Dermatitis; Glycosylation; Glyoxal; Guanidines; Humans; In Vitro Techniques; Lysine; Models, Biological; Skin Aging; Transcriptome

2017
Effect of rosmarinic acid and carnosic acid on AGEs formation in vitro.
    Food chemistry, 2017, Apr-15, Volume: 221

    Topics: Abietanes; Animals; Cattle; Cinnamates; Depsides; Glucose; Glycation End Products, Advanced; Glyoxal; Lysine; Protein Carbonylation; Pyruvaldehyde; Rosmarinic Acid; Serum Albumin, Bovine

2017
Influence of Quercetin and Its Methylglyoxal Adducts on the Formation of α-Dicarbonyl Compounds in a Lysine/Glucose Model System.
    Journal of agricultural and food chemistry, 2017, Mar-15, Volume: 65, Issue:10

    Topics: Glucose; Glyoxal; Hot Temperature; Lysine; Maillard Reaction; Molecular Structure; Pyruvaldehyde; Quercetin; Tandem Mass Spectrometry

2017
Evaluation of an olive leaf extract as a natural source of antiglycative compounds.
    Food research international (Ottawa, Ont.), 2017, Volume: 92

    Topics: Chromatography, Liquid; Deoxyglucose; Fructosamine; Galactose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Olea; Ornithine; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrimidines; Pyruvaldehyde; Tandem Mass Spectrometry

2017
Formation of Pentosidine Cross-Linking in Myoglobin by Glyoxal: Detection of Fluorescent Advanced Glycation End Product.
    Journal of fluorescence, 2017, Volume: 27, Issue:4

    Topics: Arginine; Cross-Linking Reagents; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Myoglobin

2017
The advanced glycation end product N
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:3

    Topics: Caco-2 Cells; Glycation End Products, Advanced; Glyoxal; Humans; Lysine; Serotonin

2018
Protein Repair from Glycation by Glyoxals by the DJ-1 Family Maillard Deglycases.
    Advances in experimental medicine and biology, 2017, Volume: 1037

    Topics: Acrylamide; Animals; Arginine; Bacteria; Bacterial Proteins; Cysteine; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Maillard Reaction; Protein Deglycase DJ-1; Protein Processing, Post-Translational

2017
Modification of chickpea cystatin by reactive dicarbonyl species: Glycation, oxidation and aggregation.
    Archives of biochemistry and biophysics, 2018, 07-15, Volume: 650

    Topics: Arginine; Cicer; Cystatins; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Oxidation-Reduction; Plant Proteins; Protein Aggregates; Pyruvaldehyde

2018
Investigating the Glycating Effects of Glucose, Glyoxal and Methylglyoxal on Human Sperm.
    Scientific reports, 2018, 06-13, Volume: 8, Issue:1

    Topics: DNA Damage; Fertility; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lysine; Male; Pyruvaldehyde; Semen Analysis; Sperm Count; Sperm Motility; Spermatozoa

2018
Impact of free N
    Food & function, 2018, Jul-17, Volume: 9, Issue:7

    Topics: Caco-2 Cells; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Lysine; Maillard Reaction; Receptors, Serotonin; Serotonin; Serum Albumin, Bovine

2018
Modification and Cross-Linking of Proteins by Glycolaldehyde and Glyoxal: A Model System.
    Journal of agricultural and food chemistry, 2018, Oct-17, Volume: 66, Issue:41

    Topics: Acetaldehyde; Cross-Linking Reagents; Glycation End Products, Advanced; Glyoxal; Isoelectric Point; Lysine; Maillard Reaction; Molecular Weight; Oxidation-Reduction; Protein Multimerization; Ribonuclease, Pancreatic

2018
Maillard reaction derived from oil-tea camellia seed through roasting.
    Journal of the science of food and agriculture, 2019, Aug-30, Volume: 99, Issue:11

    Topics: Amino Acids; Camellia; Chemical Phenomena; Food Handling; Furaldehyde; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Hydrogen-Ion Concentration; Lysine; Maillard Reaction; Plant Oils; Seeds; Sugars; Water

2019
Formation of α-Dicarbonyls from Dairy Related Carbohydrates with and without Nα-Acetyl-l-Lysine during Incubation at 40 and 50 °C.
    Journal of agricultural and food chemistry, 2019, Jun-05, Volume: 67, Issue:22

    Topics: Animals; Cattle; Dairy Products; Galactose; Glucose; Glyoxal; Hot Temperature; Lactose; Lysine; Maillard Reaction; Milk; Oligosaccharides; Oxidation-Reduction; Pyruvaldehyde

2019
Formation of N
    Food research international (Ottawa, Ont.), 2019, Volume: 121

    Topics: Camellia sinensis; Catechin; Food Analysis; Food Handling; Gallic Acid; Glyoxal; Lysine; Plant Leaves; Polyphenols; Pyruvaldehyde; Tea

2019
Site-specific chemoproteomic profiling of targets of glyoxal.
    Future medicinal chemistry, 2019, Volume: 11, Issue:23

    Topics: Glycation End Products, Advanced; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Glycosylation; Glyoxal; Humans; Lysine; MCF-7 Cells; Proteins; Proteomics

2019
Corn silk extract inhibit the formation of N
    Food chemistry, 2020, Mar-30, Volume: 309

    Topics: Antioxidants; Caseins; Chromatography, High Pressure Liquid; Fatty Acids; Flavonoids; Glucose; Glyoxal; Lysine; Models, Biological; Plant Extracts; Silk; Tandem Mass Spectrometry; Zea mays

2020
Study of Aberrant Modifications in Peptides as a Test Bench to Investigate the Immunological Response to Non-Enzymatic Glycation.
    Folia biologica, 2019, Volume: 65, Issue:4

    Topics: Diabetes Mellitus, Type 1; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Imidazoles; Immunoassay; Ketoses; Lysine; Peptides; Protein Processing, Post-Translational; Pyruvaldehyde

2019
Non-nutritive sweeteners are in concomitant with the formation of endogenous and exogenous advanced glycation end-products.
    International journal of food sciences and nutrition, 2020, Volume: 71, Issue:6

    Topics: Cooking; Electrophoresis, Polyacrylamide Gel; Fructosamine; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Lysine; Non-Nutritive Sweeteners; Proof of Concept Study; Sorbitol; Sucrose; Xylitol

2020
Formation and migration of α-dicarbonyl compounds during storage and reheating of a sugary food simulation system.
    Journal of the science of food and agriculture, 2020, Mar-30, Volume: 100, Issue:5

    Topics: Carbohydrates; Deoxyglucose; Diacetyl; Food; Food Analysis; Food Storage; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Lysine; Pyruvaldehyde; Temperature

2020
Gastrointestinal digestion of dietary advanced glycation endproducts using an in vitro model of the gastrointestinal tract (TIM-1).
    Food & function, 2020, Jul-22, Volume: 11, Issue:7

    Topics: Animals; Arginine; Chromatography, Liquid; Digestion; Fruit and Vegetable Juices; Gastrointestinal Tract; Glycation End Products, Advanced; Glyoxal; Hepatitis A Virus Cellular Receptor 1; Humans; Lysine; Milk; Pyruvaldehyde; Tandem Mass Spectrometry; Zingiber officinale

2020
Novel Amidine Protein Cross-Links Formed by the Reaction of Glyoxal with Lysine.
    Journal of agricultural and food chemistry, 2021, Jul-21, Volume: 69, Issue:28

    Topics: Amidines; Glycation End Products, Advanced; Glyoxal; Lysine; Maillard Reaction; Tandem Mass Spectrometry

2021
Mapping protein carboxymethylation sites provides insights into their role in proteostasis and cell proliferation.
    Nature communications, 2021, 11-18, Volume: 12, Issue:1

    Topics: Aging; Animals; Cell Line; Cell Proliferation; Endothelial Cells; Glycosylation; Glyoxal; Humans; Lysine; Methylation; Mice; Mice, Inbred C57BL; Microtubules; Primary Cell Culture; Protein Processing, Post-Translational; Proteins; Proteomics; Proteostasis; Tubulin

2021
Novel Pyridinium Cross-Link Structures Derived from Glycolaldehyde and Glyoxal.
    Journal of agricultural and food chemistry, 2022, Apr-13, Volume: 70, Issue:14

    Topics: Acetaldehyde; Glycation End Products, Advanced; Glyoxal; Lysine; Maillard Reaction

2022
Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form
    International journal of molecular sciences, 2022, Mar-22, Volume: 23, Issue:7

    Topics: Esters; Gas Chromatography-Mass Spectrometry; Glycation End Products, Advanced; Glyoxal; Hydrogen-Ion Concentration; Lysine; Magnesium Oxide; Phosphates; Pyruvaldehyde; Schiff Bases

2022
Maillard reaction indicators formation, changes and possible intake in infant formula produced by different thermal treatments during domestic use.
    Food chemistry, 2022, Nov-30, Volume: 395

    Topics: Glycation End Products, Advanced; Glyoxal; Humans; Infant; Infant Formula; Lysine; Maillard Reaction

2022
Maillard reaction products and amino acid cross-links in liquid infant formula: Effects of UHT treatment and storage.
    Food chemistry, 2022, Dec-01, Volume: 396

    Topics: Amino Acids; Glycation End Products, Advanced; Glyoxal; Humans; Infant Formula; Lysine; Lysinoalanine; Maillard Reaction; Pyruvaldehyde

2022
Lipid Peroxidation Has Major Impact on Malondialdehyde-Derived but Only Minor Influence on Glyoxal and Methylglyoxal-Derived Protein Modifications in Carbohydrate-Rich Foods.
    Journal of agricultural and food chemistry, 2022, Aug-24, Volume: 70, Issue:33

    Topics: Carbohydrates; Glycation End Products, Advanced; Glyoxal; Lipid Peroxidation; Lysine; Malondialdehyde; Proteins; Pyruvaldehyde

2022
Tuning Human Serum Albumin (HSA) Hydrogels through Albumin Glycation.
    Macromolecular bioscience, 2023, Volume: 23, Issue:3

    Topics: Fatty Acids; Glyoxal; Humans; Hydrogels; Lysine; Maillard Reaction; Serum Albumin; Serum Albumin, Human

2023
Glyoxal-derived advanced glycation end-products, N
    Molecular biology reports, 2023, Volume: 50, Issue:3

    Topics: Apoptosis; Gene Expression; Glycation End Products, Advanced; Glyoxal; Hepatocytes; Humans; Lysine; Maillard Reaction; Proteins; Pyruvaldehyde; Reactive Oxygen Species

2023
Quantitation of α-Dicarbonyls, Lysine- and Arginine-Derived Advanced Glycation End Products, in Commercial Canned Meat and Seafood Products.
    Journal of agricultural and food chemistry, 2023, May-03, Volume: 71, Issue:17

    Topics: Arginine; Glycation End Products, Advanced; Glyoxal; Lysine; Meat; Pyruvaldehyde; Seafood

2023
Application of tea polyphenols as additives in brown fermented milk: Potential analysis of mitigating Maillard reaction products.
    Journal of dairy science, 2023, Volume: 106, Issue:10

    Topics: Animals; Glycation End Products, Advanced; Glyoxal; Lysine; Magnesium Oxide; Maillard Reaction; Milk; Polyphenols; Pyruvaldehyde; Tea

2023
Study on the non-enzymatic browning of lotus rhizome juice during sterilization mediated by 1,2-dicarboxyl and heterocyclic compounds.
    Journal of the science of food and agriculture, 2024, Jan-15, Volume: 104, Issue:1

    Topics: Asparagine; Fructose; Glucose; Glutamine; Glyoxal; Heterocyclic Compounds; Lotus; Lysine; Maillard Reaction; Pyruvaldehyde; Rhizome; Sterilization

2024
Effect of edible oil type on the formation of protein-bound N
    Food research international (Ottawa, Ont.), 2023, Volume: 174, Issue:Pt 1

    Topics: Animals; Corn Oil; Glyoxal; Humans; Linoleic Acid; Linolenic Acids; Linseed Oil; Lysine; Oleic Acid; Olive Oil; Palmitic Acid; Plant Oils; Pork Meat; Red Meat; Swine; Tandem Mass Spectrometry

2023