glyoxal has been researched along with alpha-chymotrypsin in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, K | 1 |
| Jörnvall, H; Lange, LG; Riordan, JF; Vallee, BL | 1 |
| Busby, TF; Gan, JC | 1 |
| Chang, CC; Liou, IF; Yang, CC | 1 |
| Cohen, AB | 1 |
| Healy, A; McCarthy, N; McKervey, MA; Walker, B; Ye, T | 1 |
| Malthouse, JP; Murphy, EA; O'Connell, TP | 1 |
| Harriott, P; Healy, A; Lynas, JF; McKervey, MA; Walker, B | 1 |
| Djurdjevic-Pahl, A; Hewage, C; Malthouse, JP | 1 |
| Cosgrove, S; Hewage, C; Malthouse, JP; Rogers, L; Spink, E | 1 |
| Malthouse, JP | 1 |
| Hewage, C; Malthouse, JP; Spink, E | 1 |
| Howe, N; Malthouse, JP; O'Donohoe, CA; Petrillo, T | 1 |
| Cleary, JA; Doherty, W; Evans, P; Malthouse, JP | 1 |
1 review(s) available for glyoxal and alpha-chymotrypsin
| Article | Year |
|---|---|
13C- and 1H-NMR studies of oxyanion and tetrahedral intermediate stabilization by the serine proteinases: optimizing inhibitor warhead specificity and potency by studying the inhibition of the serine proteinases by peptide-derived chloromethane and glyoxa
Topics: Amino Acid Sequence; Chymotrypsin; Enzyme Stability; Glyoxal; Hydrogen Bonding; Hydrogen-Ion Concentration; In Vitro Techniques; Methyl Chloride; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Protons; Serine Endopeptidases; Serine Proteinase Inhibitors; Subtilisin | 2007 |
13 other study(ies) available for glyoxal and alpha-chymotrypsin
| Article | Year |
|---|---|
Further studies on the reactions of phenylglyoxal and related reagents with proteins.
Topics: Aldehydes; Amino Acids; Chymotrypsin; Glyoxal; Insulin; Muramidase; Pepsin A; Proteins; Pyruvaldehyde; Renin; Ribonucleases; Trypsin | 1977 |
Identification of a reactive arginyl residue in horse liver alcohol dehydrogenase.
Topics: Alcohol Oxidoreductases; Animals; Arginine; Binding Sites; Chymotrypsin; Glyoxal; Horses; Liver; Peptide Fragments | 1977 |
Chemical modifications of lysyl and arginyl residues of human plasma alpha1-antitrypsin.
Topics: alpha 1-Antitrypsin; Arginine; Binding Sites; Chymotrypsin; Glyoxal; Histidine; Humans; Immunodiffusion; Ketones; Kinetics; Lysine; Protein Binding | 1976 |
Studies on the status of arginine residues in cobrotoxin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Binding Sites; Biological Assay; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Epitopes; Glyoxal; Hydrogen-Ion Concentration; Immunodiffusion; Lethal Dose 50; Mice; Precipitin Tests; Protein Binding; Protein Conformation; Snakes; Spectrophotometry, Ultraviolet; Toxins, Biological; Venoms | 1974 |
Mechanism of action of alpha-1-antitrypsin.
Topics: alpha 1-Antitrypsin; Amino Acids; Anilides; Arginine; Aspartic Acid; Benzoates; Binding Sites; Binding, Competitive; Cholinesterase Inhibitors; Chymotrypsin; Fibrinolysin; Glyoxal; Histidine; Isoflurophate; Leucine; Lysine; Nitro Compounds; Pancreatic Elastase; Peptide Hydrolases; Protease Inhibitors; Serine; Structure-Activity Relationship; Subtilisins; Thrombin; Trypsin Inhibitors | 1973 |
Peptide glyoxals: a novel class of inhibitor for serine and cysteine proteinases.
Topics: Animals; Cathepsin B; Cattle; Chymotrypsin; Cysteine Proteinase Inhibitors; Dipeptides; Glyoxal; Humans; Kinetics; Pancreatic Elastase; Serine Proteinase Inhibitors; Swine | 1993 |
The synthesis and characterisation of a glyoxal inhibitor of chymotrypsin.
Topics: Chymotrypsin; Glyoxal; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylalanine; Serine Proteinase Inhibitors | 1996 |
Inhibitors of the chymotrypsin-like activity of proteasome based on di- and tri-peptidyl alpha-keto aldehydes (glyoxals).
Topics: Chymotrypsin; Cysteine Endopeptidases; Glyoxal; Humans; Multienzyme Complexes; Proteasome Endopeptidase Complex; Trypsin Inhibitors | 1998 |
13C-NMR study of the inhibition of delta-chymotrypsin by a tripeptide-glyoxal inhibitor.
Topics: Amino Acid Sequence; Animals; Carbon Isotopes; Cattle; Chymotrypsin; Drug Stability; Glyoxal; Kinetics; Magnetic Resonance Spectroscopy; Oligopeptides; Pancreas; Serine Proteinase Inhibitors; Structure-Activity Relationship; Subtilisins; Trypsin Inhibitors | 2002 |
13C and 1H NMR studies of ionizations and hydrogen bonding in chymotrypsin-glyoxal inhibitor complexes.
Topics: Animals; Binding Sites; Catalysis; Cattle; Chymotrypsin; Glyoxal; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ions; Magnetic Resonance Spectroscopy; Serine; Surface Plasmon Resonance; Temperature | 2007 |
Determination of the structure of tetrahedral transition state analogues bound at the active site of chymotrypsin using 18O and 2H isotope shifts in the 13C NMR spectra of glyoxal inhibitors.
Topics: Binding Sites; Chymotrypsin; Deuterium; Deuterium Exchange Measurement; Glyoxal; Models, Biological; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Oxygen Isotopes; Protein Binding | 2007 |
Importance of tetrahedral intermediate formation in the catalytic mechanism of the serine proteases chymotrypsin and subtilisin.
Topics: Biocatalysis; Catalytic Domain; Chymotrypsin; Glyoxal; Hydrogen Bonding; Hydrogen-Ion Concentration; Oligopeptides; Protease Inhibitors; Serine; Subtilisin | 2012 |
Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin.
Topics: Animals; Biocatalysis; Catalytic Domain; Cattle; Chymotrypsin; Glyoxal; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Protease Inhibitors; Serine; Solutions; Stereoisomerism; Thermodynamics | 2014 |