Page last updated: 2024-08-21

glycyrrhizic acid and methotrexate

glycyrrhizic acid has been researched along with methotrexate in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Al-Abed, Y; VanPatten, S1
Akimoto, M; Iwasaki, H; Kasai, M; Kimura, M; Matano, S; Nakajima, Y; Sawano, A1
Chao, PD; Hou, YC; Lin, SP; Tsai, SY1
Davey, AK; Liu, X; Wang, J; Xu, R; Yang, J; Zhang, X1
Cao, W; Ge, L; Li, W; Si, X; Sun, X; Xin, H1
Du, GQ; Wang, YM1
Chai, W; Cui, L; Gong, F; He, Z; Jia, G; Liu, X; Wen, Y1
Gowda, P; Joshi, SD; Kumawat, RK; Patrick, S; Sen, E1
Abe, K; Higurashi, T; Kawano, Y; Maeda-Minami, A; Mano, Y; Miyazaki, S; Takahashi, M1

Reviews

2 review(s) available for glycyrrhizic acid and methotrexate

ArticleYear
High Mobility Group Box-1 (HMGb1): Current Wisdom and Advancement as a Potential Drug Target.
    Journal of medicinal chemistry, 2018, 06-28, Volume: 61, Issue:12

    Topics: Alarmins; Biomarkers; HMGB1 Protein; Humans; Immunity, Innate; Inflammation; Molecular Targeted Therapy; Pathogen-Associated Molecular Pattern Molecules

2018
Low-dose methotrexate-induced vulvar edema: A case report.
    Medicine, 2019, Volume: 98, Issue:35

    Topics: Abdominal Pain; Administration, Oral; Adult; China; Female; Glycyrrhizic Acid; Humans; Injections, Intramuscular; Materia Medica; Methotrexate; Metronidazole; Pregnancy; Pregnancy, Ectopic; Treatment Outcome; Trichomonas Vaginitis; Uterine Hemorrhage; Vulvar Diseases

2019

Other Studies

9 other study(ies) available for glycyrrhizic acid and methotrexate

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
[Prevention of cancer chemotherapeutic agent-induced toxicity in postoperative breast cancer patients with glycyrrhizin (SNMC)].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Leukopenia; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Postoperative Care; Tegafur

1986
Glycyrrhizin and licorice significantly affect the pharmacokinetics of methotrexate in rats.
    Journal of agricultural and food chemistry, 2009, Mar-11, Volume: 57, Issue:5

    Topics: Administration, Oral; Animals; Drug Interactions; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Male; Methotrexate; Plant Extracts; Rats; Rats, Sprague-Dawley

2009
Effects of glycyrrhizin on biliary transport and hepatic levels of glutathione in rats.
    Biopharmaceutics & drug disposition, 2012, Volume: 33, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Bile; Biliary Tract; Biological Transport, Active; Dose-Response Relationship, Drug; Estradiol; Glutathione; Glycyrrhizic Acid; In Vitro Techniques; Liver; Male; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Perfusion; Rats; Rats, Sprague-Dawley; Substrate Specificity

2012
Erythrodermic psoriasis with bullous pemphigoid: combination treatment with methotrexate and compound glycyrrhizin.
    Diagnostic pathology, 2014, May-29, Volume: 9

    Topics: Aged; Biopsy; Dermatitis, Exfoliative; Dermatologic Agents; Drug Therapy, Combination; Glycyrrhizic Acid; Humans; Male; Methotrexate; Microscopy, Fluorescence; Pemphigoid, Bullous; Psoriasis; Skin; Treatment Outcome

2014
Glycyrrhizic acid prevents enteritis through reduction of NF‑κB p65 and p38MAPK expression in rat.
    Molecular medicine reports, 2016, Volume: 13, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Caspase 3; Cyclooxygenase 2; Cytokines; Down-Regulation; Enteritis; Enzyme-Linked Immunosorbent Assay; Glycyrrhizic Acid; Intercellular Adhesion Molecule-1; Lactic Acid; Male; Methotrexate; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Transcription Factor RelA

2016
Repurposing Methotrexate in Dampening SARS-CoV2-S1-Mediated IL6 Expression: Lessons Learnt from Lung Cancer.
    Inflammation, 2022, Volume: 45, Issue:1

    Topics: A549 Cells; Adenocarcinoma of Lung; Angiotensin-Converting Enzyme 2; Anti-Inflammatory Agents; Cell Line, Tumor; COVID-19; COVID-19 Drug Treatment; Cytokine Receptor gp130; Folate Receptor 2; Glycyrrhizic Acid; HMGB1 Protein; Humans; Immunosuppressive Agents; Interleukin-6; Janus Kinase 1; Lung Neoplasms; Methotrexate; Phosphorylation; SARS-CoV-2; Spike Glycoprotein, Coronavirus; STAT3 Transcription Factor

2022
Optimal Administration of Glycyrrhizin Avoids Pharmacokinetic Interactions With High-dose Methotrexate and Exerts a Hepatoprotective Effect.
    Anticancer research, 2023, Volume: 43, Issue:4

    Topics: Animals; Glycyrrhizic Acid; Liver; Male; Methotrexate; Rats; Rats, Wistar

2023