Page last updated: 2024-08-21

glycyrrhizic acid and beta-escin

glycyrrhizic acid has been researched along with beta-escin in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19906 (10.34)18.7374
1990's8 (13.79)18.2507
2000's10 (17.24)29.6817
2010's22 (37.93)24.3611
2020's12 (20.69)2.80

Authors

AuthorsStudies
Diaz, P; Falcocchio, S; Pastor, FI; Ruiz, C; Saso, L1
Herrmann, F; Wink, M1
Chen, FK; Guo, YZ; Kano, Y; Meng, XS1
Hayashi, Y; Ishiguro, I; Kuroda, K; Nagamura, Y; Nishida, K; Saito, S; Sasaki, Y1
Campbell, JB; Chavali, SR; Francis, T1
Amagaya, S; Iwama, H; Ogihara, Y1
Hiai, S; Oguro, C; Sasayama, Y1
Kimura, I; Kimura, M; Nojima, H1
Han, DW; Li, CM; Ma, XH; Yin, L; Zhao, MQ; Zhao, YC1
Azaz, E; Milo-Goldzweig, I; Segal, R1
Li, Q; Murakamio, T; Okita, K; Takahashi, M1
Hattori, T; Isobe, K; Iwamoto, T; Kato, M; Lwin, T; Nagase, F; Nakashima, I; Pu, MY; Yanagita, N; Zhang, YH1
Ishihara, K; Ito, K; Kosuge, E; Kuriyama, M; Nakamura, T1
Arai, I; Hirai, Y; Ida, Y; Komatsu, Y; Kuroiwa, Y; Sasaki, K; Shingu, K; Taguchi, S; Yamamoto, T; Yamaura, H1
Kashimoto, T; Kudo, K; Tachikawa, E; Takahashi, E1
Hiai, S; Nagasawa, T; Zhang, ZQ; Zhou, QL1
Chen, Y; Sørensen, LK1
Ebizuka, Y; Hayashi, H; Hiraoka, N; Huang, P; Ikeshiro, Y; Inoue, K; Kirakosyan, A; Kushiro, T; Shibuya, M1
Dixon, RA; Sumner, LW1
Hirakawa, T; Kinjo, J; Nagao, T; Nohara, T; Okabe, H; Okawa, M; Tsuchihashi, R1
Matsumura, Y; Rauchensteiner, F; Tani, T; Yamaji, S; Yamamoto, Y1
Chen, T; Dong, Y; Sun, Y; Xu, Q; Zhang, L1
Daines, AM; Greatrex, BW; Hayman, CM; Hook, SM; McBurney, WT; Rades, T; Rendle, PM; Sims, IM1
Kang, HS; Kim, CJ; Lee, JY; Moon, HJ; Park, BE; Sim, SS1
Cai, X; Cao, AP; Chen, CW; Chen, HZ; Chen, Y; Chen, YG; Fu, QC; Li, J; Lu, LG; Mao, YM; Sui, YH; Sun, Y; Wu, SM; Zeng, MD; Zhao, W1
Gotoh, T; Hokari, M; Hori, K; Sugiyama, T; Takahashi, S1
Cheng, XL; Cui, XB; Li, P; Peng, GP; Peng, YB; Qi, LW; Ren, MT; Zheng, YF1
Maldini, M; Montoro, P; Piacente, S; Pizza, C; Postorino, S; Russo, M1
Shoyama, Y; Tuvshintogtokh, I; Uto, T1
Ding, L; Du, XL; Qi, XM; Shakya, S; Yang, XL; Yang, ZL; Zhu, H1
Cichoń, T; Jarosz, M; Kamysz, W; Kobusińska, M; Lesiak, M; Matuszczak, S; Mitrus, I; Sieroń, A; Smolarczyk, R; Szala, S1
Berger, M; de Paula, FT; Frauches, PQ; Gnoatto, SC; Gossmann, G; Graebin, CS; Guimarães, JA; Pedebos, C; Verli, H1
Sakamoto, S; Shoyama, Y; Uto, T1
Mo, Y; Yan, Y; Zhang, D1
Buschauer, A; Hensel, A; Jose, J; Lengers, I; Melzig, MF; Orlando, Z1
Duan, TX; Lin, ZZ; Sun, Y; Yang, ZL; Yuan, RJ; Zhan, XY1
Chen, G; Chen, J; Liu, P; Mu, Y; Ren, S; Sun, M; Tong, X; Wang, X; Zhang, H; Zhou, Y1
Guo, J; Ma, L; Sun, Y; Wan, Z; Wang, J; Yang, X; Yin, S1
Ding, D; Huang, J; Lei, S; Lin, F; Liu, X; Ma, J; Mao, D; Shi, L; Zhang, S; Zhang, Y1
Adachi, I; Ito, T; Kato, A; Onikata, S; Tomohara, K1
Guo, J; Ma, L; Sun, Y; Wan, Z; Yang, X; Yin, S1
Chen, R; Huang, C; Li, B; Li, J; Liu, Y; Ma, T; Meng, X; Shen, C; Wu, M; Xu, Q1
Hanashima, S; Malabed, R; Murata, M; Sakurai, K1
Gong, MX; He, R; Li, J; Li, ZX; Lu, Y; Ma, TT; Wang, ZM; Wu, S; Xu, YS; Zhang, C1
Huang, PY; Liu, F; Wang, RS; Wang, RX; Xu, YH; Yang, AP; Zhao, TT; Zheng, ZG; Zhu, Q1
Hayashi, H; Horikawa, M; Kaku, T; Mizutani, M; Muranaka, T; Nomura, Y; Ohyama, K; Ono, E; Saito, K; Seki, H; Sudo, H; Suzuki, T; Tamura, K1
Chen, LH; Duan, WP; Li, CY; Peng, GP; Xu, ZY; Yang, Y; Zheng, YF1
Bouhoute, M; Fainassi, F; Hafidi, A; Isoda, H; Kobayashi, I; Nakajima, M; Neves, MA; Taarji, N; Tominaga, K1
Chen, C; Cheng, K; Dai, L; Hu, K; Li, H; Liu, L; Sun, H; Wen, X; Xu, Q; Yuan, H1
Chung, SY; Fujisawa, Y; Hiraga, S; Ishimoto, M; Muranaka, T; Nomura, Y; Saito, K; Seki, H; Shimoda, Y1
Fanani, MZ; Fukushima, EO; Ishimori, M; Muranaka, T; Ohyama, K; Saito, K; Sawai, S; Seki, H; Sudo, H1
Jiang, J; Li, Y; Liu, P; Ma, Y; Meng, C; Shi, R; Wang, T; Wang, Y; Wu, J; Yuan, W; Zeng, J; Zhang, H; Zhong, J; Zhu, L1
Chen, L; Chen, X; Wang, X; Wu, J; Wu, Y; Xu, C; Xu, H; Yang, L1
Guo, J; Li, Q; Wan, Z; Xu, M; Yang, X; Yang, Y1
Li, Q; Ma, L; Ngai, T; Wan, Z; Wu, J; Xu, M; Yang, X1
Dai, Z; Deng, K; Yang, D; Yang, P; Zhou, Y1
Cao, M; Chen, D; Diao, N; Guo, C; Kong, M; Liu, Z; Su, Y; Wang, H1
Chen, J; Du, R; Li, Q; Wan, Z; Yang, X; Yu, X1

Reviews

1 review(s) available for glycyrrhizic acid and beta-escin

ArticleYear
Legume natural products: understanding and manipulating complex pathways for human and animal health.
    Plant physiology, 2003, Volume: 131, Issue:3

    Topics: Alkaloids; Amino Acids; Animals; Biological Products; Chalcone; Chalcones; Fabaceae; Genistein; Genomics; Glycyrrhizic Acid; Humans; Isoflavones; Molecular Structure; Plant Shoots; Pterocarpans; Saponins; Triterpenes

2003

Trials

3 trial(s) available for glycyrrhizic acid and beta-escin

ArticleYear
[Magnesium isoglycyrrhizinate in the treatment of chronic liver diseases: a randomized, double-blind, multi-doses, active drug controlled, multi-center study].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:11

    Topics: Alanine Transaminase; Anti-Inflammatory Agents; Aspartate Aminotransferases; Chronic Disease; Double-Blind Method; Fatty Liver; Female; Glycyrrhizic Acid; Humans; Injections, Intravenous; Liver; Liver Diseases; Liver Diseases, Alcoholic; Male; Saponins; Triterpenes

2009
[Magnesium isoglycyrrhizinate prevention of chemotherapy-induced liver damage during initial treatment of patients with gastrointestinal tumors].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2015, Volume: 23, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Bilirubin; Capecitabine; Chemical and Drug Induced Liver Injury; Deoxycytidine; Fluorouracil; Gastrointestinal Neoplasms; Glycyrrhizic Acid; Humans; Leucovorin; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Prospective Studies; Saponins; Triterpenes

2015
Pharmacokinetics-based comprehensive strategy to identify multiple effective components in Huangqi decoction against liver fibrosis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 84

    Topics: Adolescent; Adult; Animals; Chalcone; Chromatography, Liquid; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Humans; Liver Cirrhosis; Male; Mass Spectrometry; Mice, Inbred C57BL; Middle Aged; Saponins; Triterpenes; Young Adult

2021

Other Studies

54 other study(ies) available for glycyrrhizic acid and beta-escin

ArticleYear
Helicobacter pylori EstV: identification, cloning, and characterization of the first lipase isolated from an epsilon-proteobacterium.
    Applied and environmental microbiology, 2007, Volume: 73, Issue:8

    Topics: Carboxylesterase; Cloning, Molecular; Coenzymes; Computational Biology; DNA, Bacterial; Enzyme Inhibitors; Enzyme Stability; Escin; Genome, Bacterial; Glycyrrhizic Acid; Helicobacter pylori; Hydrogen-Ion Concentration; Lipase; Polymerase Chain Reaction; Sequence Homology; Substrate Specificity; Temperature

2007
Synergistic interactions of saponins and monoterpenes in HeLa cells, Cos7 cells and in erythrocytes.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Oct-15, Volume: 18, Issue:13

    Topics: Animals; Bicyclic Monoterpenes; Chlorocebus aethiops; COS Cells; Cricetinae; Digitonin; Drug Resistance, Microbial; Drug Synergism; Escin; Glycyrrhizic Acid; HeLa Cells; Humans; Menthol; Monoterpenes; Plant Extracts; Plants, Medicinal; Quillaja; Saponins; Thymol

2011
[The identification and determination of marker substances in xiaoyao wan by three dimensional HPLC].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1992, Volume: 27, Issue:11

    Topics: Benzoates; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Monoterpenes; Oleanolic Acid; Sapogenins; Saponins

1992
Preparation of glycyrrhetic acid glycosides having various beta(1----2)-linked disaccharides and their cytoprotective effects on carbon tetrachloride-induced hepatic injury.
    Chemical & pharmaceutical bulletin, 1991, Volume: 39, Issue:9

    Topics: Animals; Carbohydrate Sequence; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disaccharides; Glycosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Liver Diseases; Molecular Sequence Data; Rats; Rats, Inbred Strains; Saponins

1991
An in vitro study of immunomodulatory effects of some saponins.
    International journal of immunopharmacology, 1987, Volume: 9, Issue:6

    Topics: Animals; Anti-Infective Agents; B-Lymphocytes; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Growth Substances; In Vitro Techniques; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Quillaja; Quillaja Saponins; Saponins; Spleen; T-Lymphocytes

1987
Studies of the combined use of steroid and Shosaikoto, one of the Kampohozai (Chinese traditional medicine), on pituitary adrenocortical axis function and immune responses.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:2

    Topics: Adrenal Glands; Animals; Body Weight; Corticosterone; Drugs, Chinese Herbal; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hemagglutinins; Hemolytic Plaque Technique; Immunity; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Organ Size; Pituitary-Adrenal System; Plant Extracts; Plants, Medicinal; Prednisolone; Rats; Rats, Inbred Strains; Rosette Formation; Sapogenins; Saponins; Spleen

1986
Chronic effects of ginseng saponin, glycyrrhizin and flavin adenine dinucleotide on adrenal and thymus weight in normal and dexamethasone-treated rats.
    Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:1

    Topics: Adrenal Glands; Animals; Dexamethasone; Flavin-Adenine Dinucleotide; Glycyrrhetinic Acid; Glycyrrhizic Acid; Male; Organ Size; Panax; Plants, Medicinal; Rats; Rats, Inbred Strains; Saponins; Thymus Gland

1987
Depolarizing neuromuscular blocking action induced by electropharmacological coupling in the combined effect of paeoniflorin and glycyrrhizin.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:4

    Topics: Acetylcholine; Action Potentials; Animals; Anti-Inflammatory Agents; Benzoates; Bridged-Ring Compounds; Caffeine; Electrophysiology; Glucosides; Glycosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; In Vitro Techniques; Male; Mice; Monoterpenes; Motor Endplate; Neuromuscular Depolarizing Agents; Saponins; Succinylcholine; Synapses

1985
[Preventive and therapeutic actions of glycyrrhizin, glycyrrhetic acid and crude saikosides on experimental liver cirrhosis in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:5

    Topics: Animals; Collagen; Fatty Liver; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis; Liver Cirrhosis; Male; Oleanolic Acid; Rats; Sapogenins; Saponins

1983
Hemolysis caused by polyoxyethylene-derived surfactants. Evidence for peroxide participation.
    Biochimica et biophysica acta, 1981, Sep-07, Volume: 646, Issue:3

    Topics: Animals; Cetomacrogol; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hemolysin Proteins; Hemolysis; Peroxides; Polyethylene Glycols; Rats; Sapogenins; Saponins; Surface-Active Agents

1981
Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 1993, Volume: 2, Issue:2

    Topics: alpha-Fetoproteins; Antineoplastic Agents; Astringents; Carcinoma, Hepatocellular; Cell Cycle; Cell Death; Cell Division; DNA, Neoplasm; Drugs, Chinese Herbal; Flavanones; Flavonoids; Ginsenosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Liver Neoplasms; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins; Tumor Cells, Cultured

1993
Characterization of the immunoregulatory action of saikosaponin-d.
    Cellular immunology, 1994, Volume: 159, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Blotting, Northern; Cell Division; Fluorescent Antibody Technique; Genes, fos; Glycyrrhetinic Acid; Glycyrrhizic Acid; Immunosuppressive Agents; Interleukin-2; Mice; Mice, Inbred C57BL; Oleanolic Acid; Phosphorylation; Receptors, Interleukin-2; Sapogenins; Saponins; Signal Transduction; Spleen; T-Lymphocytes; Tyrosine; Up-Regulation

1994
Effects of saiboku-to (TJ-96) on the production of platelet-activating factor in human neutrophils.
    Annals of the New York Academy of Sciences, 1993, Jun-23, Volume: 685

    Topics: Drugs, Chinese Herbal; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Immunosuppressive Agents; Medicine, Kampo; Neutrophils; Oleanolic Acid; Platelet Activating Factor; Sapogenins; Saponins

1993
Stimulative effects of saponin from kikyo-to, a Japanese herbal medicine, on pancreatic exocrine secretion of conscious rats.
    Planta medica, 1997, Volume: 63, Issue:5

    Topics: Animals; Atropine; Cholecystokinin; Duodenum; Esters; Gabexate; Glycyrrhizic Acid; Guanidines; Japan; Male; Pancreas; Pancreatic Juice; Plant Extracts; Plant Roots; Plants, Medicinal; Proglumide; Rats; Rats, Wistar; Receptors, Cholecystokinin; Saponins; Triterpenes; Trypsin; Trypsin Inhibitors

1997
Properties of ginseng saponin inhibition of catecholamine secretion in bovine adrenal chromaffin cells.
    European journal of pharmacology, 1998, Jan-12, Volume: 341, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cardiac Glycosides; Catecholamines; Cattle; Central Nervous System Agents; Chromaffin Cells; Dose-Response Relationship, Drug; Ginsenosides; Glycyrrhizic Acid; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins

1998
[The structure activity relationship of saikosaponins and glycyrrhizin derivatives for Na+, K(+)-ATPase inhibiting action].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:7

    Topics: Cell-Free System; Glycyrrhizic Acid; Humans; Oleanolic Acid; Sapogenins; Saponins; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship

1996
Determination of marker constituents in radix Glycyrrhizae and radix Notoginseng by near infrared spectroscopy.
    Fresenius' journal of analytical chemistry, 2000, Volume: 367, Issue:5

    Topics: Calibration; Chromatography, High Pressure Liquid; Ginsenosides; Glycyrrhiza; Glycyrrhizic Acid; Medicine, Chinese Traditional; Panax; Phytotherapy; Plants, Medicinal; Reference Standards; Reproducibility of Results; Saponins; Spectrophotometry, Infrared

2000
Cloning and characterization of a cDNA encoding beta-amyrin synthase involved in glycyrrhizin and soyasaponin biosyntheses in licorice.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:8

    Topics: Amino Acid Sequence; Blotting, Northern; Blotting, Southern; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Glycyrrhiza; Glycyrrhizic Acid; Intramolecular Transferases; Molecular Sequence Data; Oleanolic Acid; RNA, Messenger; Saccharomyces cerevisiae; Saponins

2001
Hepatoprotective constituents in plants. 14. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:9

    Topics: Carbohydrate Sequence; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Glucuronides; Glycyrrhizic Acid; Humans; Liver; Molecular Sequence Data; Oleanolic Acid; Saponins; tert-Butylhydroperoxide

2003
Analysis and comparison of Radix Glycyrrhizae (licorice) from Europe and China by capillary-zone electrophoresis (CZE).
    Journal of pharmaceutical and biomedical analysis, 2005, Jul-15, Volume: 38, Issue:4

    Topics: China; Chromatography, High Pressure Liquid; DNA Fingerprinting; Electrophoresis, Capillary; Ethanol; Europe; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Isoflavones; Phenols; Plant Extracts; Principal Component Analysis; Saponins; Solvents

2005
Role of four major components in the effect of Si-Ni-San, a traditional Chinese prescription, against contact sensitivity in mice.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:9

    Topics: Animals; Benzoates; Bridged-Ring Compounds; Cell Adhesion; Cells, Cultured; Concanavalin A; Dermatitis, Allergic Contact; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Flavanones; Glucosides; Glycyrrhizic Acid; Immunosuppressive Agents; Interferon-gamma; Lymphocyte Activation; Lymphocytes; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Monoterpenes; Nitric Oxide; Oleanolic Acid; Picryl Chloride; RNA, Messenger; Saponins; Spleen

2006
Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems.
    Bioorganic & medicinal chemistry, 2009, Jul-15, Volume: 17, Issue:14

    Topics: Animals; Cholesterol; Dendritic Cells; Glycosylation; Glycyrrhizic Acid; Hematopoiesis; Hematopoietic Stem Cells; ISCOMs; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Nanostructures; Oleanolic Acid; Phospholipids; Saponins

2009
Inhibitory effects of Geijigajakyak-Tang on trinitrobenzene sulfonic acid-induced colitis.
    Journal of ethnopharmacology, 2009, Nov-12, Volume: 126, Issue:2

    Topics: Acrolein; Animals; Anti-Inflammatory Agents; Antioxidants; Benzoates; Bridged-Ring Compounds; Chemotaxis; Colitis; Cyclohexanols; Eucalyptol; Female; Glucosides; Glycyrrhizic Acid; Ileum; Lipid Peroxidation; Magnoliopsida; Malondialdehyde; Mice; Mice, Inbred BALB C; Models, Animal; Monoterpenes; Muscle Contraction; Muscle, Smooth; Neutrophils; Parasympatholytics; Peroxidase; Phytotherapy; Plant Extracts; Saponins; Trinitrobenzenesulfonic Acid; Triterpenes

2009
Inhibition of human renin activity by saponins.
    Biomedical research (Tokyo, Japan), 2010, Volume: 31, Issue:2

    Topics: Fruit; Glycine max; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Oleanolic Acid; Renin; Saponins

2010
Oleanane-type triterpene glucuronides from the roots of Glycyrrhiza uralensis Fischer.
    Planta medica, 2010, Volume: 76, Issue:13

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Female; Glycyrrhiza; Glycyrrhizic Acid; HeLa Cells; Humans; Molecular Structure; Neoplasms; Phytotherapy; Plant Extracts; Plant Roots; Saponins; Structure-Activity Relationship

2010
Metabolic profiling of roots of liquorice (Glycyrrhiza glabra) from different geographical areas by ESI/MS/MS and determination of major metabolites by LC-ESI/MS and LC-ESI/MS/MS.
    Journal of pharmaceutical and biomedical analysis, 2011, Feb-20, Volume: 54, Issue:3

    Topics: Antioxidants; Calibration; Chromatography, High Pressure Liquid; Chromatography, Liquid; Flavonoids; Glycyrrhiza; Glycyrrhizic Acid; Humans; Magnetic Resonance Imaging; Mass Spectrometry; Phenols; Plant Extracts; Plant Roots; Reproducibility of Results; Saponins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2011
Preparation of knockout extract for determination of really active compound using MAb.
    Current drug discovery technologies, 2011, Volume: 8, Issue:1

    Topics: Antibodies, Monoclonal; Chromatography, Affinity; Complex Mixtures; Ginsenosides; Glycyrrhizic Acid; Immunoassay; Nitric Oxide; Nitric Oxide Synthase Type II; Oleanolic Acid; Panax; Plant Extracts; Rhizome; Saponins

2011
Determination of asperosaponin VI in dog plasma by high-performance liquid chromatography-tandem mass spectrometry and its application to a pilot pharmacokinetic study.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:1

    Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dogs; Glycyrrhizic Acid; Limit of Detection; Linear Models; Pilot Projects; Reproducibility of Results; Saponins; Tandem Mass Spectrometry

2012
The role of Glycyrrhizin, an inhibitor of HMGB1 protein, in anticancer therapy.
    Archivum immunologiae et therapiae experimentalis, 2012, Volume: 60, Issue:5

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Proliferation; Endothelial Cells; Glycyrrhizic Acid; HMGB1 Protein; Humans; Inflammation; Melanoma, Experimental; Mice; Necrosis; NIH 3T3 Cells; Peptides; Rats; Saponins

2012
Improving the thrombin inhibitory activity of glycyrrhizin, a triterpenic saponin, through a molecular simplification of the carbohydrate moiety.
    Chemical biology & drug design, 2013, Volume: 82, Issue:6

    Topics: Binding Sites; Carbohydrates; Catalytic Domain; Enzyme Activation; Glycyrrhiza; Glycyrrhizic Acid; Humans; Molecular Docking Simulation; Plant Roots; Protein Binding; Saponins; Serine Proteinase Inhibitors; Thrombin

2013
Effect of glycyrrhetinic acid on lipid raft model at the air/water interface.
    Biochimica et biophysica acta, 2015, Volume: 1848, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Air; Cholesterol; Glycyrrhetinic Acid; Glycyrrhizic Acid; Lipid Bilayers; Membrane Microdomains; Phosphatidylcholines; Saponins; Sphingomyelins; Surface Properties; Water

2015
Autodisplay of Human Hyaluronidase Hyal-1 on Escherichia coli and Identification of Plant-Derived Enzyme Inhibitors.
    Molecules (Basel, Switzerland), 2015, Aug-26, Volume: 20, Issue:9

    Topics: Antigens, Neoplasm; Cell Membrane; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Glycyrrhizic Acid; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Plant Extracts; Saponins

2015
[Feature Selection and Interpretation in Infrared Quantitative Models of Liquiritin and Glycyrrhizin in Radix Glycyrrhizae].
    Guang pu xue yu guang pu fen xi = Guang pu, 2015, Volume: 35, Issue:9

    Topics: Algorithms; Flavanones; Flavonoids; Glucosides; Glycyrrhiza; Glycyrrhizic Acid; Least-Squares Analysis; Models, Theoretical; Plant Roots; Saponins; Spectrum Analysis

2015
Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-β1/Smads signaling pathway modulation.
    Journal of ethnopharmacology, 2016, Aug-22, Volume: 190

    Topics: Actins; Animals; Astragalus Plant; Cell Line; Cell Survival; Collagen Type I; Common Bile Duct; Dimethylnitrosamine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation; Glycyrrhizic Acid; Hepatic Stellate Cells; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Male; Mice; Phosphorylation; Phytotherapy; Plants, Medicinal; Protective Agents; Rats, Wistar; RNA, Messenger; Saponins; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1

2016
Thermoresponsive structured emulsions based on the fibrillar self-assembly of natural saponin glycyrrhizic acid.
    Food & function, 2017, Jan-25, Volume: 8, Issue:1

    Topics: Emulsions; Glycyrrhizic Acid; Hot Temperature; Nanofibers; Saponins

2017
[Inhibitory effect of jianpi-jiedu prescription-contained serum on colorectal cancer SW48 cell proliferation by mTOR-P53-P21 signalling pathway].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2016, Nov-28, Volume: 41, Issue:11

    Topics: Animals; Apigenin; Blotting, Western; Cell Cycle; Cell Division; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Drugs, Chinese Herbal; Flow Cytometry; Ginsenosides; Glycyrrhizic Acid; Humans; Lactones; Phosphorylation; RNA, Messenger; Saponins; Sesquiterpenes; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes; Tumor Suppressor Protein p53

2016
Discovery of hyaluronidase inhibitors from natural products and their mechanistic characterization under DMSO-perturbed assay conditions.
    Bioorganic & medicinal chemistry letters, 2017, 04-01, Volume: 27, Issue:7

    Topics: Animals; Binding Sites; Catechin; Cattle; Dimethyl Sulfoxide; Drug Discovery; Enzyme Assays; Enzyme Inhibitors; Glycyrrhizic Acid; Hyaluronoglucosaminidase; Male; Octoxynol; Panax; Plant Extracts; Prunus domestica; Saponins

2017
Responsive Emulsion Gels with Tunable Properties Formed by Self-Assembled Nanofibrils of Natural Saponin Glycyrrhizic Acid for Oil Structuring.
    Journal of agricultural and food chemistry, 2017, Mar-22, Volume: 65, Issue:11

    Topics: Emulsions; Gels; Glycyrrhizic Acid; Nanofibers; Oils; Saponins; Stress, Mechanical

2017
The permeability characteristics and interaction of main components from Si-Ni-San in a MDCK epithelial cell monolayer model.
    Xenobiotica; the fate of foreign compounds in biological systems, 2021, Volume: 51, Issue:2

    Topics: Animals; Biological Transport; Dogs; Drugs, Chinese Herbal; Flavanones; Glucosides; Glycyrrhizic Acid; Humans; Madin Darby Canine Kidney Cells; Models, Biological; Monoterpenes; Oleanolic Acid; Permeability; Saponins; Verapamil

2021
Sterol-recognition ability and membrane-disrupting activity of Ornithogalum saponin OSW-1 and usual 3-O-glycosyl saponins.
    Biochimica et biophysica acta. Biomembranes, 2017, Volume: 1859, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Biological Transport; Cholestenones; Cholesterol; Digitonin; Dimyristoylphosphatidylcholine; Erythrocyte Membrane; Fluoresceins; Glycyrrhizic Acid; Hemolysis; Humans; Membrane Lipids; Oleanolic Acid; Ornithogalum; Phosphatidylcholines; Saponins; Unilamellar Liposomes

2017
[Study on correlation between color and effective components contents of Glycyrrhiza uralensis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:19

    Topics: Color; Flavonoids; Glycyrrhetinic Acid; Glycyrrhiza uralensis; Glycyrrhizic Acid; Phytochemicals; Plants, Medicinal; Saponins

2017
Screening bioactive components of Glycyrrhiza uralensis Fisch. with isolated perfused lung extraction and HPLC-ESI-MS
    Journal of pharmaceutical and biomedical analysis, 2019, May-30, Volume: 169

    Topics: A549 Cells; Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Chromatography, High Pressure Liquid; Flavanones; Glucosides; Glycyrrhiza; Glycyrrhiza uralensis; Glycyrrhizic Acid; Humans; Isoflavones; Lung; Phytochemicals; Plant Extracts; Rats; Rats, Wistar; Saponins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2019
Functional specialization of UDP-glycosyltransferase 73P12 in licorice to produce a sweet triterpenoid saponin, glycyrrhizin.
    The Plant journal : for cell and molecular biology, 2019, Volume: 99, Issue:6

    Topics: Arginine; Gene Expression Regulation, Plant; Glycosyltransferases; Glycyrrhiza uralensis; Glycyrrhizic Acid; Kinetics; Molecular Docking Simulation; Mutation; Phylogeny; Plant Roots; Plants, Medicinal; Saponins; Transcriptome; Triterpenes; Uridine Diphosphate Glucuronic Acid

2019
[Comparative study of water characteristic components of Glycyrrhiza uralensis from three geographical regions by chemical pattern recognition combined with muti-component qualitative and quantitative analysis].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019, Volume: 44, Issue:12

    Topics: China; Geography; Glycyrrhiza uralensis; Glycyrrhizic Acid; Plant Extracts; Saponins; Water

2019
Interfacial and emulsifying properties of purified glycyrrhizin and non-purified glycyrrhizin-rich extracts from liquorice root (Glycyrrhiza glabra).
    Food chemistry, 2021, Feb-01, Volume: 337

    Topics: Emulsifying Agents; Emulsions; Glycyrrhiza; Glycyrrhizic Acid; Plant Extracts; Saponins; Soybean Oil; Surface Tension; Water

2021
Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Glycyrrhizic Acid; Humans; Interleukin-6; Liver; Macrophages; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Oleanolic Acid; Pentacyclic Triterpenes; Phosphorylation; Sapogenins; Saponins; Tumor Necrosis Factor-alpha

2021
A cellulose synthase-derived enzyme catalyses 3-O-glucuronosylation in saponin biosynthesis.
    Nature communications, 2020, 11-16, Volume: 11, Issue:1

    Topics: Biocatalysis; Biosynthetic Pathways; Endoplasmic Reticulum; Gene Expression Regulation, Plant; Glucosyltransferases; Glucuronic Acid; Glycine max; Glycosylation; Glycyrrhiza uralensis; Glycyrrhizic Acid; Likelihood Functions; Lotus; Phylogeny; Saccharomyces cerevisiae; Saponins; Substrate Specificity; Triterpenes; Uridine Diphosphate Glucuronic Acid

2020
Allylic Hydroxylation Activity Is a Source of Saponin Chemodiversity in the Genus Glycyrrhiza.
    Plant & cell physiology, 2021, May-11, Volume: 62, Issue:2

    Topics: Cytochrome P-450 Enzyme System; Glycyrrhiza; Glycyrrhiza uralensis; Glycyrrhizic Acid; Hydroxylation; Metabolic Networks and Pathways; Phylogeny; Plant Proteins; Saponins

2021
Magnesium isoglycyrrhizinate prevents cadmium-induced activation of JNK and apoptotic hepatocyte death by reversing ROS-inactivated PP2A.
    The Journal of pharmacy and pharmacology, 2021, Dec-07, Volume: 73, Issue:12

    Topics: Animals; Apoptosis; Cadmium; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Environmental Pollutants; Glycyrrhizic Acid; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; Liver; MAP Kinase Signaling System; Mice; Oxidative Stress; Protein Phosphatase 2; Reactive Oxygen Species; Saponins; Signal Transduction; Triterpenes

2021
Tailoring structure and properties of long-lived emulsion foams stabilized by a natural saponin glycyrrhizic acid: Role of oil phase.
    Food research international (Ottawa, Ont.), 2021, Volume: 150, Issue:Pt A

    Topics: Aerosols; Emulsions; Glycyrrhizic Acid; Oils; Saponins

2021
Robust and highly adaptable high internal phase gel emulsions stabilized solely by a natural saponin hydrogelator glycyrrhizic acid.
    Food & function, 2022, Jan-04, Volume: 13, Issue:1

    Topics: Emulsions; Gels; Glycyrrhizic Acid; Nanofibers; Saponins; Viscosity

2022
LPS-induced macrophage exosomes promote the activation of hepatic stellate cells and the intervention study of total astragalus saponins combined with glycyrrhizic acid.
    Anatomical record (Hoboken, N.J. : 2007), 2023, Volume: 306, Issue:12

    Topics: Exosomes; Glycyrrhizic Acid; Hepatic Stellate Cells; Humans; Lipopolysaccharides; Liver Cirrhosis; Macrophages; Saponins

2023
A novel saponin liposomes based on the couplet medicines of
    Drug delivery, 2022, Volume: 29, Issue:1

    Topics: Glycyrrhiza uralensis; Glycyrrhizic Acid; Humans; Liposomes; Lung Neoplasms; Plant Roots; Platycodon; Saponins

2022
Thermoresponsive Dual-Structured Gel Emulsions Stabilized by Glycyrrhizic Acid Nanofibrils in Combination with Monoglyceride Crystals.
    Molecules (Basel, Switzerland), 2022, Oct-03, Volume: 27, Issue:19

    Topics: Delayed-Action Preparations; Emulsions; Glycerides; Glycyrrhizic Acid; Monoglycerides; Saponins; Water

2022
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