glycyrrhetyl 3-monoglucuronide has been researched along with glycyrrhizic acid in 12 studies
| Studies (glycyrrhetyl 3-monoglucuronide) | Trials (glycyrrhetyl 3-monoglucuronide) | Recent Studies (post-2010) (glycyrrhetyl 3-monoglucuronide) | Studies (glycyrrhizic acid) | Trials (glycyrrhizic acid) | Recent Studies (post-2010) (glycyrrhizic acid) |
|---|---|---|---|---|---|
| 22 | 0 | 7 | 2,079 | 70 | 1,068 |
| Protein | Taxonomy | glycyrrhetyl 3-monoglucuronide (IC50) | glycyrrhizic acid (IC50) |
|---|---|---|---|
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Homo sapiens (human) | 0.0115 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 1 | Mus musculus (house mouse) | 0.0135 | |
| Corticosteroid 11-beta-dehydrogenase isozyme 2 | Homo sapiens (human) | 0.0007 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iga, T; Kawakami, J; Kotaki, H; Santa, T; Sawada, Y; Uchino, K; Yamamura, Y | 1 |
| Kanaoka, M; Kato, H; Nakada, T; Yano, S | 1 |
| Akao, T | 2 |
| Han, MJ; Kim, DH; Lee, SW | 1 |
| Han, MJ; Kim, DH; Park, HY; Park, SH; Yoon, HK | 1 |
| Kase, Y; Kido, A; Kubota, K; Morita, T; Ohtake, N; Takeda, S; Tsuchiya, N | 1 |
| Inoue, K; Makino, T; Mizukami, H; Ohtake, N; Okajima, K; Uebayashi, R | 1 |
| Cao, Y; Xiao, Q; Xu, R; Yang, J | 1 |
| Fan, R; Gao, Y; Li, N; Wang, L; Xiang, J; Xu, H | 1 |
| Dai, D; Huo, Y; Li, C; Liu, G; Wang, D; Wang, X | 1 |
| Hirasawa, A; Ishiuchi, K; Maki, Y; Makino, T; Mitamura, M; Morinaga, O; Ohkita, T; Tian, C; Yasujima, T; Yuasa, H | 1 |
12 other study(ies) available for glycyrrhetyl 3-monoglucuronide and glycyrrhizic acid
| Article | Year |
|---|---|
Selective high-performance liquid chromatographic method for the determination of glycyrrhizin and glycyrrhetic acid-3-O-glucuronide in biological fluids: application of ion-pair extraction and fluorescence labelling agent.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Coumarins; Fluorescent Dyes; Glycyrrhetinic Acid; Glycyrrhizic Acid; Ions; Rats; Spectrometry, Fluorescence; Spectrometry, Mass, Fast Atom Bombardment | 1991 |
Synthesis and separation of 18 beta-glycyrrhetyl monoglucuronide from serum of a patient with glycyrrhizin-induced pseudo-aldosteronism.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Hyperaldosteronism; Spectrophotometry, Ultraviolet | 1986 |
Distribution of enzymes involved in the metabolism of glycyrrhizin in various organs of rat.
Topics: 3-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Animals; Chromatography; Durapatite; Glucuronidase; Glycyrrhetinic Acid; Glycyrrhizic Acid; Lysosomes; Male; Microsomes, Liver; Rats; Rats, Wistar; Subcellular Fractions; Tissue Distribution | 1998 |
Biotransformation of glycyrrhizin to 18beta-glycyrrhetinic acid-3-O-beta-D-glucuronide by Streptococcus LJ-22, a human intestinal bacterium.
Topics: Animals; Biotransformation; Cattle; Glucuronidase; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Hydrogen-Ion Concentration; Intestines; Molecular Weight; Rats; Streptococcus; Substrate Specificity; Sweetening Agents | 1999 |
Differences in the metabolism of glycyrrhizin, glycyrrhetic acid and glycyrrhetic acid monoglucuronide by human intestinal flora.
Topics: Clostridium; Eubacterium; Feces; Female; Glucuronidase; Glycyrrhetinic Acid; Glycyrrhizic Acid; Gram-Positive Cocci; Humans; Intestines; Middle Aged | 2000 |
Anti-allergic activity of 18beta-glycyrrhetinic acid-3-O-beta-D-glucuronide.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Cell Line; Dermatitis, Contact; Dexamethasone; Disease Models, Animal; Drug Evaluation, Preclinical; Glucuronides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Injections, Intraperitoneal; Intestines; Male; Mice; Mice, Inbred ICR; Nitrites; Oxazolone; Passive Cutaneous Anaphylaxis; Streptococcus | 2004 |
A possible involvement of 3-monoglucuronyl-glycyrrhetinic acid, a metabolite of glycyrrhizin (GL), in GL-induced pseudoaldosteronism.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Furosemide; Glycyrrhetinic Acid; Glycyrrhizic Acid; Guinea Pigs; Hyperaldosteronism; Hypokalemia; Injections, Intravenous; Male; Potassium; Sweetening Agents | 2007 |
3-Monoglucuronyl-glycyrrhretinic acid is a substrate of organic anion transporters expressed in tubular epithelial cells and plays important roles in licorice-induced pseudoaldosteronism by inhibiting 11β-hydroxysteroid dehydrogenase 2.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Cell Line, Transformed; Epithelial Cells; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; HEK293 Cells; Humans; Kidney; Liddle Syndrome; Liver; Male; Microsomes; Organic Anion Transporters; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2012 |
Comparison of the exposure of glycyrrhizin and its metabolites and the pseudoaldosteronism after intravenous administration of alpha- and beta-glycyrrhizin in rat.
Topics: Animals; Area Under Curve; Cortisone; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hydrocortisone; Kidney; Liddle Syndrome; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2013 |
The mechanism of hydrothermal hydrolysis for glycyrrhizic acid into glycyrrhetinic acid and glycyrrhetinic acid 3-O-mono-β-D-glucuronide in subcritical water.
Topics: Glycyrrhetinic Acid; Glycyrrhizic Acid; Hydrolysis; Thermodynamics; Water | 2016 |
Identification of isoliquiritigenin as an activator that stimulates the enzymatic production of glycyrrhetinic acid monoglucuronide.
Topics: Biocatalysis; Biotransformation; Chalcones; Chromatography, High Pressure Liquid; Fungal Proteins; Glucuronidase; Glucuronides; Glycyrrhetinic Acid; Glycyrrhiza; Glycyrrhizic Acid; Kinetics; Penicillium; Plant Extracts | 2017 |
Isolation of a novel glycyrrhizin metabolite as a causal candidate compound for pseudoaldosteronism.
Topics: Animals; ATP-Binding Cassette Transporters; Dogs; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Liddle Syndrome; Madin Darby Canine Kidney Cells; Male; Mice; Mice, Inbred BALB C; Organic Anion Transport Protein 1; Rats; Rats, Sprague-Dawley; Rats, Wistar; Renal Elimination | 2018 |