glycylsarcosine has been researched along with acyclovir in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Ganapathy, ME; Ganapathy, V; Huang, W; Leibach, FH; Wang, H | 1 |
| Amidon, GL; Han, HK; Oh, DM | 1 |
| Balimane, PV; Guo, A; Hu, P; Leibach, FH; Sinko, PJ | 1 |
| Hashimoto, Y; Inui, KI; Saito, H; Sawada, K; Terada, T | 1 |
| Inui, K; Irie, M; Saito, H; Sawada, K; Terada, T | 1 |
| Amidon, GL; Chu, X; Fleisher, D; Komorowski, TE; Landowski, CP; Sun, D; Wallsten, R | 1 |
| Anand, BS; Mitra, AK; Patel, J | 1 |
| Atluri, H; Dias, C; Mitra, A; Nashed, Y | 1 |
| Smith, DE; Yang, B | 1 |
1 review(s) available for glycylsarcosine and acyclovir
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
11 other study(ies) available for glycylsarcosine and acyclovir
| Article | Year |
|---|---|
Exploring the role of different drug transport routes in permeability screening.
Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2005 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.
Topics: Acyclovir; Animals; Antiviral Agents; Biological Transport, Active; Caco-2 Cells; Carrier Proteins; Cell Line; Dipeptides; HeLa Cells; Humans; Intestinal Mucosa; Kidney; Kinetics; Peptide Transporter 1; Prodrugs; Rats; Recombinant Proteins; Symporters; Valacyclovir; Valine | 1998 |
Cellular uptake mechanism of amino acid ester prodrugs in Caco-2/hPEPT1 cells overexpressing a human peptide transporter.
Topics: Acyclovir; Amino Acids; Anti-HIV Agents; Antiviral Agents; Binding, Competitive; Biological Transport; Caco-2 Cells; Cadherins; Carrier Proteins; Dipeptides; Esters; Humans; Hydrolysis; Kinetics; Membrane Transport Proteins; Prodrugs; Valacyclovir; Valine; Zidovudine | 1998 |
Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line.
Topics: Acyclovir; Animals; Anti-Bacterial Agents; Antiviral Agents; Biological Transport; Caco-2 Cells; Carrier Proteins; CHO Cells; Cricetinae; Dipeptides; Humans; Hydrogen-Ion Concentration; Kinetics; Lactams; Peptide Transporter 1; Rabbits; Rats; Symporters; Transfection; Valacyclovir; Valine | 1999 |
Recognition of L-amino acid ester compounds by rat peptide transporters PEPT1 and PEPT2.
Topics: Acyclovir; Amino Acids; Animals; Carrier Proteins; Dipeptides; Dose-Response Relationship, Drug; LLC-PK1 Cells; Prodrugs; Rats; Swine; Transfection; Valacyclovir; Valine | 1999 |
Recognition and transport characteristics of nonpeptidic compounds by basolateral peptide transporter in Caco-2 cells.
Topics: Acyclovir; Aminolevulinic Acid; Antiviral Agents; ATP-Binding Cassette Transporters; Caco-2 Cells; Carrier Proteins; Diethyl Pyrocarbonate; Dipeptides; Humans; Peptide Transporter 1; Photosensitizing Agents; Symporters; Valacyclovir; Valine | 2001 |
Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein.
Topics: Acyclovir; Blotting, Western; Caco-2 Cells; Carrier Proteins; Cell Membrane; Cephalexin; Depression, Chemical; Dipeptides; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microscopy, Confocal; Peptide Transporter 1; Recombinant Fusion Proteins; Subcellular Fractions; Symporters; Transfection; Valacyclovir; Valine | 2001 |
Interactions of the dipeptide ester prodrugs of acyclovir with the intestinal oligopeptide transporter: competitive inhibition of glycylsarcosine transport in human intestinal cell line-Caco-2.
Topics: Acyclovir; Binding, Competitive; Caco-2 Cells; Carrier Proteins; Dipeptides; Drug Interactions; Esters; Humans; Intestinal Mucosa; Intestines; Oligopeptides; Peptide Transporter 1; Prodrugs; Symporters | 2003 |
Ocular penetration of acyclovir and its peptide prodrugs valacyclovir and val-valacyclovir following systemic administration in rabbits: An evaluation using ocular microdialysis and LC-MS.
Topics: Acyclovir; Animals; Antiviral Agents; Aqueous Humor; Area Under Curve; Chromatography, Liquid; Dipeptides; Evaluation Studies as Topic; Eye; Male; Mass Spectrometry; Microdialysis; Models, Animal; Ocular Physiological Phenomena; Prodrugs; Rabbits; Time Factors; Tritium; Valacyclovir; Valine; Vitreous Body | 2002 |
Significance of peptide transporter 1 in the intestinal permeability of valacyclovir in wild-type and PepT1 knockout mice.
Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Binding, Competitive; Biotransformation; Cefadroxil; Chromatography, High Pressure Liquid; Colon; Dipeptides; Duodenum; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Mice; Mice, Knockout; Models, Biological; Peptide Transporter 1; Perfusion; Permeability; Reproducibility of Results; Symporters; Valacyclovir; Valine | 2013 |