Compounds > glycylglutamine
Page last updated: 2024-09-03

glycylglutamine and naloxone

glycylglutamine has been researched along with naloxone in 5 studies

Compound Research Comparison

Studies
(glycylglutamine)		Trials
(glycylglutamine)		Recent Studies (post-2010)
(glycylglutamine)		Studies
(naloxone)		Trials
(naloxone)		Recent Studies (post-2010) (naloxone)
10481420,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomyglycylglutamine (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Millington, WR; Owen, MD; Unal, CB1
Khan, S; Smith, ME1
Gürün, S; Millington, WR; Owen, MD; Zaloga, GP1
Gürün, MS; Millington, WR; Ulus, IH1
Cavun, S; Göktalay, G; Millington, WR1

Other Studies

5 other study(ies) available for glycylglutamine and naloxone

ArticleYear
Beta-endorphin-induced cardiorespiratory depression is inhibited by glycyl-L-glutamine, a dipeptide derived from beta-endorphin processing.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: Animals; beta-Endorphin; Blood Pressure; Dipeptides; Heart Rate; Male; Naloxone; Neurotransmitter Agents; Pro-Opiomelanocortin; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Respiration; Structure-Activity Relationship

1994
Actions of beta-endorphin peptides on the contractions of mouse diaphragm muscle.
    Peptides, 1997, Volume: 18, Issue:1

    Topics: Animals; Benzylidene Compounds; beta-Endorphin; Diaphragm; Dipeptides; Electric Stimulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Mice; Mice, Inbred C57BL; Muscle Contraction; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Neostigmine; Oligopeptides; Peptide Fragments

1997
Glycyl-L-glutamine [beta-endorphin-(30-31)] attenuates hemorrhagic hypotension in conscious rats.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Animals; Blood Pressure; Cerebral Ventricles; Dipeptides; Heart Rate; Hemorrhage; Hypotension; Injections, Intraventricular; Male; Naloxone; Neural Inhibition; Pulse; Rats; Rats, Sprague-Dawley; Stereoisomerism

1997
Choline potentiates the pressor response evoked by glycyl-glutamine or naloxone in haemorrhaged rats.
    Clinical and experimental pharmacology & physiology, 2003, Volume: 30, Issue:9

    Topics: Animals; Blood Pressure; Choline; Dipeptides; Drug Synergism; Female; Heart Rate; Hemorrhage; Male; Naloxone; Pressoreceptors; Rats; Rats, Sprague-Dawley

2003
Glycyl-glutamine, an endogenous beta-endorphin-derived peptide, inhibits morphine-induced conditioned place preference, tolerance, dependence, and withdrawal.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Conditioning, Operant; Dipeptides; Dose-Response Relationship, Drug; Drug Tolerance; Food; Injections, Intraventricular; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Substance Withdrawal Syndrome

2005