Page last updated: 2024-09-03

glycylglutamine and morphine

glycylglutamine has been researched along with morphine in 4 studies

Compound Research Comparison

Studies
(glycylglutamine)
Trials
(glycylglutamine)
Recent Studies (post-2010)
(glycylglutamine)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
10481444,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomyglycylglutamine (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Callahan, MF; Millington, WR; Owen, MD; Trivedi, K; Unal, CB; York, C1
Cavun, S; Göktalay, G; Millington, WR1
Basaran, NF; Buyukuysal, RL; Cavun, S; Millington, WR1
Aydin, S; Basaran, NF; Buyukuysal, RL; Cavun, S; Millington, WR; Sertac Yilmaz, M1

Other Studies

4 other study(ies) available for glycylglutamine and morphine

ArticleYear
Glycyl-glutamine inhibits the respiratory depression, but not the antinociception, produced by morphine.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:5

    Topics: Acidosis; Analgesia; Animals; Carbon Dioxide; Dipeptides; Hydrogen-Ion Concentration; Hypercapnia; Hypoxia; Injections, Intraventricular; Male; Morphine; Oxygen; Pain Measurement; Rats; Rats, Sprague-Dawley; Respiration

2000
Glycyl-glutamine, an endogenous beta-endorphin-derived peptide, inhibits morphine-induced conditioned place preference, tolerance, dependence, and withdrawal.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; beta-Endorphin; Conditioning, Operant; Dipeptides; Dose-Response Relationship, Drug; Drug Tolerance; Food; Injections, Intraventricular; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Substance Withdrawal Syndrome

2005
Glycyl-glutamine (beta-endorphin(30-31)) inhibits morphine-induced dopamine efflux in the nucleus accumbens.
    Naunyn-Schmiedeberg's archives of pharmacology, 2010, Volume: 381, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Dipeptides; Dopamine; Dose-Response Relationship, Drug; Male; Microdialysis; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Time Factors

2010
The effect of Gly-Gln [ß-endorphin30-31] on morphine-evoked serotonin and GABA efflux in the nucleus accumbens of conscious rats.
    Neuropeptides, 2016, Volume: 58

    Topics: Animals; Dipeptides; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin

2016