Page last updated: 2024-09-03

glycyl-prolyl-arginyl-proline and fibrinogen

glycyl-prolyl-arginyl-proline has been researched along with fibrinogen in 33 studies

Compound Research Comparison

Studies
(glycyl-prolyl-arginyl-proline)
Trials
(glycyl-prolyl-arginyl-proline)
Recent Studies (post-2010)
(glycyl-prolyl-arginyl-proline)
Studies
(fibrinogen)
Trials
(fibrinogen)
Recent Studies (post-2010) (fibrinogen)
5701034,4771,7077,083

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199012 (36.36)18.7374
1990's9 (27.27)18.2507
2000's7 (21.21)29.6817
2010's3 (9.09)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Doolittle, RF; Yamazumi, K1
Hatton, MW; Moar, SL; Richardson, M1
Adelman, B; Gennings, C; Hanners, E; Strony, J1
Greenberg, CS; Miraglia, CC2
Greenberg, CS; Miraglia, CC; Rickles, FR; Shuman, MA1
Achyuthan, KE; Dobson, JV; Greenberg, CS1
Ferry, JD; Schindlauer, G; Shimizu, A1
Doolittle, RF; Kuyas, C1
Harfenist, EJ; Mustard, JF; Packham, MA1
Guccione, MA; Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA1
Higgins, DL; Lewis, SD; Shafer, JA1
Root-Bernstein, RS; Westall, FC1
Guccione, MA; Harfenist, EJ; Mustard, JF; Packham, MA1
Cummins, HZ; Hurlet-Jensen, A; Liu, CY; Nossel, HL1
Anvari, N; Ofosu, FA; Okwusidi, JI1
Diamond, SL; Wu, JH1
Chen, XC; Dong, C; Hua, ZC; Zhu, DX1
Bennick, A; Brosstad, F; Haddeland, U; Nieuwenhuizen, W; Sletten, K1
De Cristofaro, R; Landolfi, R1
Dardik, R; Rubinstein, E; Savion, N; Shenkman, B; Tamarin, I; Varon, D1
Chernishov, VI; Gritsenko, PG; Kolesnikova, IN; Komisarenko, SV; Lugovskoy, EV; Nieuwenhuizen, W; Zolotarova, EN1
Herrmann, M; Kehrel, BE; Morgenstern, E; Niemann, S; Peters, G; Spehr, N; Van Aken, H1
Gallistl, S; Muntean, W; Zenz, W1
Galanakis, DK; Gorkun, OV; Litvinov, RI; Medved, L; Shuman, H; Weisel, JW; Yakovlev, S1
Geer, CB; Gorkun, OV; Lord, ST; Schoenfisch, MH; Tripathy, A1
Weisel, JW1
Fujihara, N; Haneishi, A; Hirota-Kawadobora, M; Lord, ST; Okumura, N; Ota, H; Terasawa, F; Yamauchi, K1
Choi, JR; Choi, TY; Gorkun, OV; Hong, SY; Lord, ST; Park, R; Ping, L; Song, J1
Abaeva, AA; Alessi, MC; Ataullakhanov, FI; Canault, M; Chambost, H; Kolyadko, VN; Kotova, YN; Mazurov, AV; Nurden, AT; Obydennyy, SI; Panteleev, MA; Podoplelova, NA; Yakimenko, AO1
Chen, P; Chen, W; Li, Y; Wang, L; Wu, M; Zhang, H1
Chen, H; He, A; He, Q; Luo, Y; Tao, A; Yan, J; Zhang, C1
Crossen, J; Diamond, SL1

Other Studies

33 other study(ies) available for glycyl-prolyl-arginyl-proline and fibrinogen

ArticleYear
The synthetic peptide Gly-Pro-Arg-Pro-amide limits the plasmic digestion of fibrinogen in the same fashion as calcium ion.
    Protein science : a publication of the Protein Society, 1992, Volume: 1, Issue:12

    Topics: Calcium; Electrophoresis, Polyacrylamide Gel; Fibrinogen; Fibrinolysin; Humans; Oligopeptides; Peptide Fragments

1992
Enhanced binding of fibrinogen by the subendothelium after treatment of the rabbit aorta with thrombin.
    The Journal of laboratory and clinical medicine, 1990, Volume: 115, Issue:3

    Topics: Animals; Aorta, Thoracic; Basement Membrane; Binding Sites; Biological Transport; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibrinogen; Fibrinolysin; Heparin; In Vitro Techniques; Oligopeptides; Rabbits; Thrombin

1990
Synergistic inhibition of platelet aggregation by fibrinogen-related peptides.
    Circulation research, 1990, Volume: 67, Issue:4

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Drug Synergism; Fibrinogen; Humans; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors

1990
Measurement of blood coagulation Factor XIIIa formation in plasma containing glycyl-L-prolyl-L-arginyl-L-proline.
    Analytical biochemistry, 1985, Volume: 144, Issue:1

    Topics: Blood Coagulation Tests; Catalysis; Factor XIII; Fibrin; Fibrinogen; Hot Temperature; Humans; In Vitro Techniques; Oligopeptides; Thrombin; Transglutaminases

1985
Cleavage of blood coagulation factor XIII and fibrinogen by thrombin during in vitro clotting.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:5

    Topics: Binding Sites; Blood Coagulation; Blood Platelets; Electrophoresis, Polyacrylamide Gel; Factor XIII; Fibrin; Fibrinogen; Humans; In Vitro Techniques; Oligopeptides; Thrombin; Time Factors; Transglutaminases

1985
The effect of fibrin polymers on thrombin-catalyzed plasma factor XIIIa formation.
    Blood, 1985, Volume: 66, Issue:2

    Topics: Afibrinogenemia; Calcium; Edetic Acid; Factor XIII; Fibrin; Fibrinogen; Humans; Kinetics; Oligopeptides; Thrombin; Transglutaminases

1985
Gly-Pro-Arg-Pro modifies the glutamine residues in the alpha- and gamma-chains of fibrinogen: inhibition of transglutaminase cross-linking.
    Biochimica et biophysica acta, 1986, Aug-15, Volume: 872, Issue:3

    Topics: Animals; Cattle; Factor XIII; Fibrin; Fibrinogen; Glutamine; Kinetics; Macromolecular Substances; Methylamines; Oligopeptides; Polymers; Putrescine; Transglutaminases

1986
Interaction of the fibrinogen-binding tetrapeptide Gly-Pro-Arg-Pro with fine clots and oligomers of alpha-fibrin; comparisons with alpha beta-fibrin.
    Biopolymers, 1988, Volume: 27, Issue:5

    Topics: Blood Coagulation; Fibrin; Fibrinogen; Humans; Macromolecular Substances; Oligopeptides

1988
Gly-Pro-Arg-Pro derivatives that bind to human plasma albumin and prevent fibrin formation.
    Thrombosis research, 1986, Aug-15, Volume: 43, Issue:4

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Fibrin; Fibrinogen; Humans; Kinetics; Oligopeptides; Protein Binding; Serum Albumin; Structure-Activity Relationship; Thrombin Time

1986
Comparison of the interactions of fibrinogen and soluble fibrin with washed rabbit platelets stimulated with ADP.
    Thrombosis and haemostasis, 1985, Apr-22, Volume: 53, Issue:2

    Topics: Adenosine Diphosphate; Alprostadil; Animals; Apyrase; Blood Platelets; Creatine Kinase; Edetic Acid; Fibrin; Fibrinogen; Oligopeptides; Phosphocreatine; Platelet Aggregation; Prostaglandins E; Rabbits

1985
Arachidonate-induced fibrinogen binding to thrombin-degranulated rabbit platelets is independent of released ADP.
    Blood, 1982, Volume: 59, Issue:5

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cytoplasmic Granules; Fibrin; Fibrinogen; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Thrombin

1982
Steady state kinetic parameters for the thrombin-catalyzed conversion of human fibrinogen to fibrin.
    The Journal of biological chemistry, 1983, Aug-10, Volume: 258, Issue:15

    Topics: Edetic Acid; Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Kinetics; Mathematics; Oligopeptides; Thrombin

1983
Fibrinopeptide A binds Gly-Pro-Arg-Pro.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:14

    Topics: Amino Acid Sequence; Binding Sites; Delta Sleep-Inducing Peptide; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Magnetic Resonance Spectroscopy; Oligopeptides

1984
The use of the synthetic peptide, Gly-Pro-Arg-Pro, in the preparation of thrombin-degranulated rabbit platelets.
    Blood, 1982, Volume: 59, Issue:5

    Topics: Animals; Blood Platelets; Cytoplasmic Granules; Dose-Response Relationship, Drug; Fibrin; Fibrinogen; Oligopeptides; Platelet Aggregation; Rabbits; Serotonin; Thrombin

1982
Fibrin polymerization and release of fibrinopeptide B by thrombin.
    Thrombosis research, 1982, Aug-15, Volume: 27, Issue:4

    Topics: Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Oligopeptides; Peptides; Spectrophotometry; Thrombin

1982
Modulation of intrinsic prothrombin activation by fibrinogen and fibrin I.
    The Journal of laboratory and clinical medicine, 1993, Volume: 121, Issue:1

    Topics: Factor IX; Factor X; Fibrin; Fibrinogen; Humans; Oligopeptides; Prothrombin; Thrombin

1993
Fluorogenic fibrinogen and fibrin facilitate macromolecular assembly and dynamic assay of picomolar levels of plasminogen activators under well mixed conditions.
    Thrombosis and haemostasis, 1995, Volume: 74, Issue:2

    Topics: alpha-2-Antiplasmin; Amino Acid Sequence; Antifibrinolytic Agents; Blood Proteins; Enzyme Activation; Fibrin; Fibrinogen; Fibrinolysin; Fibrinolysis; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Fluorometry; Humans; Macromolecular Substances; Molecular Sequence Data; Oligopeptides; Plasminogen; Protein Binding; Recombinant Proteins; Sensitivity and Specificity; Solutions; Surface Properties; Templates, Genetic; Thrombin; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

1995
Characterization of a recombinant chimeric plasminogen activator composed of Gly-Pro-Arg-Pro tetrapeptide and truncated urokinase-type plasminogen activator expressed in Escherichia coli.
    Biochemical and biophysical research communications, 1996, May-15, Volume: 222, Issue:2

    Topics: Base Sequence; Blotting, Western; Cloning, Molecular; Escherichia coli; Fibrin; Fibrinogen; Fibrinolysis; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Oligopeptides; Recombinant Fusion Proteins; Urokinase-Type Plasminogen Activator

1996
Aggregated, conformationally changed fibrinogen exposes the stimulating sites for t-PA-catalysed plasminogen activation.
    Thrombosis and haemostasis, 1996, Volume: 75, Issue:2

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Binding Sites; Biopolymers; Chromatography, Gel; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibrinogen; Hot Temperature; Humans; Kinetics; Molecular Sequence Data; Oligopeptides; Plasminogen; Protein Conformation; Rabbits; Tissue Plasminogen Activator

1996
Measurement of plasma fibrinogen concentration by the prothrombin-time-derived method: applicability and limitations.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1998, Volume: 9, Issue:3

    Topics: Anticoagulants; Evaluation Studies as Topic; Fibrinogen; Hirudins; Humans; Methods; Nephelometry and Turbidimetry; Oligopeptides; Prothrombin Time; Recombinant Proteins; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry

1998
Staphylococcus aureus adherence to thrombin-treated endothelial cells is mediated by fibrinogen but not by platelets.
    The Journal of laboratory and clinical medicine, 2000, Volume: 135, Issue:1

    Topics: Alprostadil; Antibodies, Blocking; Bacterial Adhesion; Blood Platelets; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibrinogen; Fibronectins; Hirudins; Humans; Oligopeptides; Staphylococcus aureus; Thrombin; von Willebrand Factor

2000
Two monoclonal antibodies to D-dimer-specific inhibitors of fibrin polymerization.
    Thrombosis research, 2004, Volume: 113, Issue:3-4

    Topics: Antibodies, Monoclonal; Antibody Specificity; Biopolymers; Blood Coagulation; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Hybridomas; Immunoglobulin Fab Fragments; Oligopeptides; Protein Structure, Tertiary

2004
Soluble fibrin is the main mediator of Staphylococcus aureus adhesion to platelets.
    Circulation, 2004, Jul-13, Volume: 110, Issue:2

    Topics: Adenosine Diphosphate; Ancrod; Animals; Bacterial Adhesion; Blood Platelet Disorders; Blood Platelets; Coagulase; Cytoplasmic Granules; Fibrin; Fibrinogen; Hirudins; Humans; Mice; Mice, Knockout; Oligopeptides; Platelet Activation; Protein Binding; Staphylococcus aureus; Thrombin; Thrombospondin 1

2004
Gly-pro-arg-pro (GPRP) enhances free thrombin.
    Thrombosis research, 1995, Jun-15, Volume: 78, Issue:6

    Topics: Blood Platelets; Fibrinogen; Humans; Kinetics; Oligopeptides; Plasma; Thrombin

1995
Polymerization of fibrin: Direct observation and quantification of individual B:b knob-hole interactions.
    Blood, 2007, Jan-01, Volume: 109, Issue:1

    Topics: Amino Acid Motifs; Amino Acid Substitution; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Models, Molecular; Mutation, Missense; Oligopeptides; Optical Tweezers; Peptide Fragments; Point Mutation; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Tertiary; Recombinant Fusion Proteins; Thrombin

2007
Role of 'B-b' knob-hole interactions in fibrin binding to adsorbed fibrinogen.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:12

    Topics: Adsorption; Batroxobin; Binding Sites; Binding, Competitive; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Hydrophobic and Hydrophilic Interactions; Models, Biological; Oligopeptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Surface Plasmon Resonance; Thrombin

2007
Which knobs fit into which holes in fibrin polymerization?
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:12

    Topics: Adsorption; Animals; Batroxobin; Binding Sites; Binding, Competitive; Factor XIIIa; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Models, Biological; Oligopeptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thrombin

2007
B:b interactions are essential for polymerization of variant fibrinogens with impaired holes 'a'.
    Journal of thrombosis and haemostasis : JTH, 2007, Volume: 5, Issue:12

    Topics: Batroxobin; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Factor XIIIa; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Kinetics; Microscopy, Electron, Scanning; Models, Biological; Mutation; Nephelometry and Turbidimetry; Oligopeptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thrombin

2007
Fibrinogen residue γAla341 is necessary for calcium binding and 'A-a' interactions.
    Thrombosis and haemostasis, 2012, Volume: 107, Issue:5

    Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Blood Coagulation; Calcium; CHO Cells; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Factor XIIIa; Fibrinogen; Fibrinogens, Abnormal; Fibrinolysin; Fibrinopeptide A; Fibrinopeptide B; Humans; Kinetics; Microscopy, Electron, Scanning; Models, Molecular; Molecular Sequence Data; Mutation; Oligopeptides; Protein Conformation; Protein Multimerization; Protein Subunits; Thrombin; Transfection; Valine

2012
Procoagulant platelets form an α-granule protein-covered "cap" on their surface that promotes their attachment to aggregates.
    The Journal of biological chemistry, 2013, Oct-11, Volume: 288, Issue:41

    Topics: Blood Coagulation; Blood Platelets; Blotting, Western; Female; Fibrin; Fibrinogen; Flow Cytometry; Humans; Microscopy, Confocal; Oligopeptides; Phosphatidylserines; Platelet Aggregation; Polymerization; Thrombasthenia; Thrombosis; Thrombospondins; Transglutaminases

2013
In vitro fibrinolysis and antithrombosis characterizations of novel recombinant microplasminogen with RGD and GPRP peptides.
    Journal of thrombosis and thrombolysis, 2016, Volume: 42, Issue:1

    Topics: Fibrinogen; Fibrinolysis; Fibrinolytic Agents; Humans; Molecular Docking Simulation; Mutagenesis, Site-Directed; Oligopeptides; Peptide Fragments; Plasminogen; Platelet Aggregation; Recombinant Proteins

2016
Fibrinogen/AKT/Microfilament Axis Promotes Colitis by Enhancing Vascular Permeability.
    Cellular and molecular gastroenterology and hepatology, 2021, Volume: 11, Issue:3

    Topics: Actin Cytoskeleton; Animals; Biopsy; Capillary Permeability; Case-Control Studies; Cell Line; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Fibrinogen; Healthy Volunteers; Humans; Intestinal Mucosa; Male; Mice; Oligopeptides; Proto-Oncogene Proteins c-akt; Signal Transduction

2021
Thermal shift assay to probe melting of thrombin, fibrinogen, fibrin monomer, and fibrin: Gly-Pro-Arg-Pro induces a fibrin monomer-like state in fibrinogen.
    Biochimica et biophysica acta. General subjects, 2021, Volume: 1865, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinogens, Abnormal; Humans; Oligopeptides; Protein Stability; Thrombin; Transition Temperature

2021