Page last updated: 2024-09-03

glycyl-prolyl-arginyl-proline and fibrin

glycyl-prolyl-arginyl-proline has been researched along with fibrin in 33 studies

Compound Research Comparison

Studies
(glycyl-prolyl-arginyl-proline)
Trials
(glycyl-prolyl-arginyl-proline)
Recent Studies (post-2010)
(glycyl-prolyl-arginyl-proline)
Studies
(fibrin)
Trials
(fibrin)
Recent Studies (post-2010) (fibrin)
5701015,9943283,808

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199013 (39.39)18.7374
1990's11 (33.33)18.2507
2000's3 (9.09)29.6817
2010's5 (15.15)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Hubbell, JA; Wagner, WR1
Greenberg, CS; Miraglia, CC2
Greenberg, CS; Miraglia, CC; Rickles, FR; Shuman, MA1
Achyuthan, KE; Dobson, JV; Greenberg, CS1
Hu, SJ; Jen, CJ1
Ferry, JD; Schindlauer, G; Shimizu, A1
Doolittle, RF; Kuyas, C1
Hantgan, RR; Lewis, JC; Taylor, RG1
Harfenist, EJ; Mustard, JF; Packham, MA1
Guccione, MA; Harfenist, EJ; Kinlough-Rathbone, RL; Mustard, JF; Packham, MA1
Higgins, DL; Lewis, SD; Shafer, JA1
Guccione, MA; Harfenist, EJ; Mustard, JF; Packham, MA1
Cummins, HZ; Hurlet-Jensen, A; Liu, CY; Nossel, HL1
Chang, MC; Huang, TF; Wang, CY1
Michelson, AD1
Anvari, N; Ofosu, FA; Okwusidi, JI1
Diamond, SL; Wu, JH1
Colman, RW; Scott, CF1
Chen, XC; Dong, C; Hua, ZC; Zhu, DX1
Chen, XC; Hua, ZC; Zhu, DX2
Chung, DW; Côté, HC; Davie, EW; Pratt, KP; Stenkamp, RE1
Lorand, L; Murthy, SN; Parameswaran, KN1
Chernishov, VI; Gritsenko, PG; Kolesnikova, IN; Komisarenko, SV; Lugovskoy, EV; Nieuwenhuizen, W; Zolotarova, EN1
Herrmann, M; Kehrel, BE; Morgenstern, E; Niemann, S; Peters, G; Spehr, N; Van Aken, H1
Galanakis, DK; Gorkun, OV; Litvinov, RI; Medved, L; Shuman, H; Weisel, JW; Yakovlev, S1
Colace, TV; Diamond, SL; Muthard, RW1
Brzoska, T; Mogami, H; Sano, H; Suzuki, Y; Urano, T1
Abaeva, AA; Alessi, MC; Ataullakhanov, FI; Canault, M; Chambost, H; Kolyadko, VN; Kotova, YN; Mazurov, AV; Nurden, AT; Obydennyy, SI; Panteleev, MA; Podoplelova, NA; Yakimenko, AO1
Heemskerk, JW; Lancé, MD; Lionikiene, AS; Mastenbroek, TG; Mutch, NJ; Swieringa, F; van der Meijden, PE; Whyte, CS1
Bouwhuis, A; de Laat, B; Hemker, HC; Huskens, D; Kelchtermans, H; Lancé, MD; Lindhout, T; Miszta, A; Pelkmans, L; Schurgers, E1
Crossen, J; Diamond, SL1

Reviews

1 review(s) available for glycyl-prolyl-arginyl-proline and fibrin

ArticleYear
Platelet activation by thrombin can be directly measured in whole blood through the use of the peptide GPRP and flow cytometry: methods and clinical applications.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1994, Volume: 5, Issue:1

    Topics: Amino Acid Sequence; Exercise; Fibrin; Flow Cytometry; Humans; Molecular Sequence Data; Oligopeptides; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Thrombin

1994

Other Studies

32 other study(ies) available for glycyl-prolyl-arginyl-proline and fibrin

ArticleYear
Local thrombin synthesis and fibrin formation in an in vitro thrombosis model result in platelet recruitment and thrombus stabilization on collagen in heparinized blood.
    The Journal of laboratory and clinical medicine, 1990, Volume: 116, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Antibodies; Antithrombins; Blood Platelets; Collagen; Factor X; Fibrin; Humans; Microscopy, Electron, Scanning; Models, Biological; Oligopeptides; Platelet Adhesiveness; Platelet Aggregation; Platelet Count; Prothrombin; Thrombin; Thrombosis

1990
Measurement of blood coagulation Factor XIIIa formation in plasma containing glycyl-L-prolyl-L-arginyl-L-proline.
    Analytical biochemistry, 1985, Volume: 144, Issue:1

    Topics: Blood Coagulation Tests; Catalysis; Factor XIII; Fibrin; Fibrinogen; Hot Temperature; Humans; In Vitro Techniques; Oligopeptides; Thrombin; Transglutaminases

1985
Cleavage of blood coagulation factor XIII and fibrinogen by thrombin during in vitro clotting.
    The Journal of clinical investigation, 1985, Volume: 75, Issue:5

    Topics: Binding Sites; Blood Coagulation; Blood Platelets; Electrophoresis, Polyacrylamide Gel; Factor XIII; Fibrin; Fibrinogen; Humans; In Vitro Techniques; Oligopeptides; Thrombin; Time Factors; Transglutaminases

1985
The effect of fibrin polymers on thrombin-catalyzed plasma factor XIIIa formation.
    Blood, 1985, Volume: 66, Issue:2

    Topics: Afibrinogenemia; Calcium; Edetic Acid; Factor XIII; Fibrin; Fibrinogen; Humans; Kinetics; Oligopeptides; Thrombin; Transglutaminases

1985
Gly-Pro-Arg-Pro modifies the glutamine residues in the alpha- and gamma-chains of fibrinogen: inhibition of transglutaminase cross-linking.
    Biochimica et biophysica acta, 1986, Aug-15, Volume: 872, Issue:3

    Topics: Animals; Cattle; Factor XIII; Fibrin; Fibrinogen; Glutamine; Kinetics; Macromolecular Substances; Methylamines; Oligopeptides; Polymers; Putrescine; Transglutaminases

1986
Direct platelet-fibrin interaction that does not require platelet activation.
    The American journal of physiology, 1987, Volume: 253, Issue:4 Pt 2

    Topics: Adenosine Diphosphate; Alprostadil; Aspirin; Blood Platelets; Egtazic Acid; Fibrin; HEPES; Humans; Hydrogen-Ion Concentration; Kinetics; Nephelometry and Turbidimetry; Oligopeptides; Platelet Aggregation; Polymers; Serotonin

1987
Interaction of the fibrinogen-binding tetrapeptide Gly-Pro-Arg-Pro with fine clots and oligomers of alpha-fibrin; comparisons with alpha beta-fibrin.
    Biopolymers, 1988, Volume: 27, Issue:5

    Topics: Blood Coagulation; Fibrin; Fibrinogen; Humans; Macromolecular Substances; Oligopeptides

1988
Gly-Pro-Arg-Pro derivatives that bind to human plasma albumin and prevent fibrin formation.
    Thrombosis research, 1986, Aug-15, Volume: 43, Issue:4

    Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Fibrin; Fibrinogen; Humans; Kinetics; Oligopeptides; Protein Binding; Serum Albumin; Structure-Activity Relationship; Thrombin Time

1986
Platelets interact with fibrin only after activation.
    Blood, 1985, Volume: 65, Issue:6

    Topics: Adenosine Diphosphate; Adult; Alprostadil; Batroxobin; Blood Platelets; Epoprostenol; Fibrin; Fibrin Fibrinogen Degradation Products; Humans; Light; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Oligopeptides; Platelet Aggregation; Prostaglandins E; Scattering, Radiation; Thrombin

1985
Comparison of the interactions of fibrinogen and soluble fibrin with washed rabbit platelets stimulated with ADP.
    Thrombosis and haemostasis, 1985, Apr-22, Volume: 53, Issue:2

    Topics: Adenosine Diphosphate; Alprostadil; Animals; Apyrase; Blood Platelets; Creatine Kinase; Edetic Acid; Fibrin; Fibrinogen; Oligopeptides; Phosphocreatine; Platelet Aggregation; Prostaglandins E; Rabbits

1985
Arachidonate-induced fibrinogen binding to thrombin-degranulated rabbit platelets is independent of released ADP.
    Blood, 1982, Volume: 59, Issue:5

    Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cytoplasmic Granules; Fibrin; Fibrinogen; Oligopeptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Thrombin

1982
Steady state kinetic parameters for the thrombin-catalyzed conversion of human fibrinogen to fibrin.
    The Journal of biological chemistry, 1983, Aug-10, Volume: 258, Issue:15

    Topics: Edetic Acid; Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Kinetics; Mathematics; Oligopeptides; Thrombin

1983
The use of the synthetic peptide, Gly-Pro-Arg-Pro, in the preparation of thrombin-degranulated rabbit platelets.
    Blood, 1982, Volume: 59, Issue:5

    Topics: Animals; Blood Platelets; Cytoplasmic Granules; Dose-Response Relationship, Drug; Fibrin; Fibrinogen; Oligopeptides; Platelet Aggregation; Rabbits; Serotonin; Thrombin

1982
Fibrin polymerization and release of fibrinopeptide B by thrombin.
    Thrombosis research, 1982, Aug-15, Volume: 27, Issue:4

    Topics: Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Oligopeptides; Peptides; Spectrophotometry; Thrombin

1982
Ancrod-formed fibrin stimulates prostacyclin production of human umbilical vein endothelial cells via de novo synthesis of cyclooxygenase.
    Biochemical and biophysical research communications, 1994, Sep-30, Volume: 203, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Ancrod; Aspirin; Blotting, Western; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelium, Vascular; Epoprostenol; Fibrin; Humans; Kinetics; Oligopeptides; Prostaglandin-Endoperoxide Synthases; Umbilical Veins

1994
Modulation of intrinsic prothrombin activation by fibrinogen and fibrin I.
    The Journal of laboratory and clinical medicine, 1993, Volume: 121, Issue:1

    Topics: Factor IX; Factor X; Fibrin; Fibrinogen; Humans; Oligopeptides; Prothrombin; Thrombin

1993
Fluorogenic fibrinogen and fibrin facilitate macromolecular assembly and dynamic assay of picomolar levels of plasminogen activators under well mixed conditions.
    Thrombosis and haemostasis, 1995, Volume: 74, Issue:2

    Topics: alpha-2-Antiplasmin; Amino Acid Sequence; Antifibrinolytic Agents; Blood Proteins; Enzyme Activation; Fibrin; Fibrinogen; Fibrinolysin; Fibrinolysis; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Fluorometry; Humans; Macromolecular Substances; Molecular Sequence Data; Oligopeptides; Plasminogen; Protein Binding; Recombinant Proteins; Sensitivity and Specificity; Solutions; Surface Properties; Templates, Genetic; Thrombin; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

1995
When and where is factor XI activated by thrombin?
    Blood, 1996, Mar-01, Volume: 87, Issue:5

    Topics: Amino Acid Sequence; Blood Platelets; Cell Membrane; Enzyme Activation; Factor XI; Feedback; Fibrin; Humans; Molecular Sequence Data; Oligopeptides; Plasma; Thrombin

1996
Characterization of a recombinant chimeric plasminogen activator composed of Gly-Pro-Arg-Pro tetrapeptide and truncated urokinase-type plasminogen activator expressed in Escherichia coli.
    Biochemical and biophysical research communications, 1996, May-15, Volume: 222, Issue:2

    Topics: Base Sequence; Blotting, Western; Cloning, Molecular; Escherichia coli; Fibrin; Fibrinogen; Fibrinolysis; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Oligopeptides; Recombinant Fusion Proteins; Urokinase-Type Plasminogen Activator

1996
Chemical conjugation of Gly-Pro-Arg-Pro. Tetrapeptide to low molecular weight urokinase.
    Biochemistry and molecular biology international, 1996, Volume: 39, Issue:3

    Topics: Caseins; Enzyme Activation; Fibrin; Fibrinolysis; Kinetics; Oligopeptides; Plasminogen; Protein Conformation; Urokinase-Type Plasminogen Activator

1996
A low molecular weight urokinase derivative with enhanced fibrin affinity.
    Biochemistry and molecular biology international, 1996, Volume: 39, Issue:4

    Topics: Chromatography, Affinity; Fibrin; Fibrinolysis; Humans; Molecular Weight; Oligopeptides; Urokinase-Type Plasminogen Activator

1996
The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Jul-08, Volume: 94, Issue:14

    Topics: Dimerization; Fibrin; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Conformation

1997
A double-headed Gly-Pro-Arg-Pro ligand mimics the functions of the E domain of fibrin for promoting the end-to-end crosslinking of gamma chains by factor XIIIa.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Jan-20, Volume: 95, Issue:2

    Topics: Cross-Linking Reagents; Fibrin; Humans; Oligopeptides; Transglutaminases

1998
Two monoclonal antibodies to D-dimer-specific inhibitors of fibrin polymerization.
    Thrombosis research, 2004, Volume: 113, Issue:3-4

    Topics: Antibodies, Monoclonal; Antibody Specificity; Biopolymers; Blood Coagulation; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Hybridomas; Immunoglobulin Fab Fragments; Oligopeptides; Protein Structure, Tertiary

2004
Soluble fibrin is the main mediator of Staphylococcus aureus adhesion to platelets.
    Circulation, 2004, Jul-13, Volume: 110, Issue:2

    Topics: Adenosine Diphosphate; Ancrod; Animals; Bacterial Adhesion; Blood Platelet Disorders; Blood Platelets; Coagulase; Cytoplasmic Granules; Fibrin; Fibrinogen; Hirudins; Humans; Mice; Mice, Knockout; Oligopeptides; Platelet Activation; Protein Binding; Staphylococcus aureus; Thrombin; Thrombospondin 1

2004
Polymerization of fibrin: Direct observation and quantification of individual B:b knob-hole interactions.
    Blood, 2007, Jan-01, Volume: 109, Issue:1

    Topics: Amino Acid Motifs; Amino Acid Substitution; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Humans; Models, Molecular; Mutation, Missense; Oligopeptides; Optical Tweezers; Peptide Fragments; Point Mutation; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Tertiary; Recombinant Fusion Proteins; Thrombin

2007
Thrombus growth and embolism on tissue factor-bearing collagen surfaces under flow: role of thrombin with and without fibrin.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: Adult; Anticoagulants; Blood Coagulation; Blood Platelets; Collagen Type I; Computer Simulation; Embolism; Factor XIIa; Fibrin; Humans; Liposomes; Male; Microfluidic Analytical Techniques; Microscopy, Confocal; Models, Biological; Numerical Analysis, Computer-Assisted; Oligopeptides; Plant Proteins; Platelet Adhesiveness; Platelet Aggregation; Regional Blood Flow; Stress, Mechanical; Thrombin; Thromboplastin; Thrombosis; Time Factors; Young Adult

2012
Binding of thrombin-activated platelets to a fibrin scaffold through α(IIb)β₃ evokes phosphatidylserine exposure on their cell surface.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Blood Coagulation; Blood Platelets; Cytochalasin B; Dipeptides; Fibrin; Humans; Microscopy, Confocal; Oligopeptides; Phosphatidylserines; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin

2013
Procoagulant platelets form an α-granule protein-covered "cap" on their surface that promotes their attachment to aggregates.
    The Journal of biological chemistry, 2013, Oct-11, Volume: 288, Issue:41

    Topics: Blood Coagulation; Blood Platelets; Blotting, Western; Female; Fibrin; Fibrinogen; Flow Cytometry; Humans; Microscopy, Confocal; Oligopeptides; Phosphatidylserines; Platelet Aggregation; Polymerization; Thrombasthenia; Thrombosis; Thrombospondins; Transglutaminases

2013
Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow.
    Blood, 2015, Apr-16, Volume: 125, Issue:16

    Topics: Blood Platelets; Crotalid Venoms; Fibrin; Fibrinolysin; Fibrinolysis; Fibrinolytic Agents; Flow Cytometry; Hemostatics; Hirudins; Lectins, C-Type; Microscopy, Confocal; Oligopeptides; Phosphatidylserines; Protein Binding; Rheology; Shear Strength; Thrombin; Thrombosis; Tirofiban; Tissue Plasminogen Activator; Tyrosine; Urokinase-Type Plasminogen Activator

2015
Simultaneous measurement of thrombin generation and fibrin formation in whole blood under flow conditions.
    Thrombosis and haemostasis, 2016, 07-04, Volume: 116, Issue:1

    Topics: Adult; Aged; Blood Loss, Surgical; Blood Viscosity; Cardiac Surgical Procedures; Dose-Response Relationship, Drug; Equipment Design; Female; Fibrin; Healthy Volunteers; Hemorheology; Humans; In Vitro Techniques; Male; Middle Aged; Oligopeptides; Predictive Value of Tests; Protein Multimerization; Thoracic Surgical Procedures; Thrombelastography; Thrombin; Tissue Plasminogen Activator

2016
Thermal shift assay to probe melting of thrombin, fibrinogen, fibrin monomer, and fibrin: Gly-Pro-Arg-Pro induces a fibrin monomer-like state in fibrinogen.
    Biochimica et biophysica acta. General subjects, 2021, Volume: 1865, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinogens, Abnormal; Humans; Oligopeptides; Protein Stability; Thrombin; Transition Temperature

2021