glycothiohexide-alpha and nosiheptide

glycothiohexide-alpha has been researched along with nosiheptide* in 1 studies

Other Studies

1 other study(ies) available for glycothiohexide-alpha and nosiheptide

Article	Year
Synthesis of the 2,3,4-trisubstituted indole fragments of nosiheptide and glycothiohexide. Organic & biomolecular chemistry, 2004, Mar-07, Volume: 2, Issue:5 Two routes to the protected 4-hydroxymethyl-3-methylindole-2-carboxylate fragment 17 of the thiopeptide antibiotic nosiheptide are described starting from methyl 4-methylindole-2-carboxylate 11, itself prepared in two steps, or from 3-amino-4-chlorobenzoic acid 26. The first route can be adapted to the synthesis of a fragment of the related antibiotic glycothiohexide-alpha, the 3,4-bis(hydroxymethyl)indole-2-carboxylate in which the two hydroxymethyl groups are differentiated as in indole 19 or the lactone 20. Topics: Doxorubicin; Indoles; Lactones; Molecular Structure; Peptides; Thiazoles	2004

Article

Year

Synthesis of the 2,3,4-trisubstituted indole fragments of nosiheptide and glycothiohexide.

Organic & biomolecular chemistry, 2004, Mar-07, Volume: 2, Issue:5

Two routes to the protected 4-hydroxymethyl-3-methylindole-2-carboxylate fragment 17 of the thiopeptide antibiotic nosiheptide are described starting from methyl 4-methylindole-2-carboxylate 11, itself prepared in two steps, or from 3-amino-4-chlorobenzoic acid 26. The first route can be adapted to the synthesis of a fragment of the related antibiotic glycothiohexide-alpha, the 3,4-bis(hydroxymethyl)indole-2-carboxylate in which the two hydroxymethyl groups are differentiated as in indole 19 or the lactone 20.

Topics: Doxorubicin; Indoles; Lactones; Molecular Structure; Peptides; Thiazoles

2004