Page last updated: 2024-09-04

glycineamide ribonucleotide and lometrexol

glycineamide ribonucleotide has been researched along with lometrexol in 2 studies

Compound Research Comparison

Studies (glycineamide ribonucleotide)	Trials (glycineamide ribonucleotide)	Recent Studies (post-2010) (glycineamide ribonucleotide)	Studies (lometrexol)	Trials (lometrexol)	Recent Studies (post-2010) (lometrexol)
12	0	0	119	7	13

Protein Interaction Comparison

Protein	Taxonomy	glycineamide ribonucleotide (IC50)	lometrexol (IC50)
Trifunctional purine biosynthetic protein adenosine-3	Homo sapiens (human)		0.0634
Trifunctional purine biosynthetic protein adenosine-3	Mus musculus (house mouse)		0.78

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andis, SL; Gossett, LS; Grindey, GB; Habeck, LL; Leitner, TA; Mendelsohn, LG; Schultz, RM; Shackelford, KA; Shih, C	1
Balcells, M; Borrell, JI; Castillo, MJ; Colominas, C; Costa, M; Martínez-Teipel, B; Matallana, JL; Schuler, E; Teixidó, J	1

Other Studies

2 other study(ies) available for glycineamide ribonucleotide and lometrexol

Article	Year
A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer research, 1994, Feb-15, Volume: 54, Issue:4 Topics: Acyltransferases; Animals; Antineoplastic Agents; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Humans; Hydroxymethyl and Formyl Transferases; Leukemia; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Phosphoribosylglycinamide Formyltransferase; Receptors, Cell Surface; Ribonucleotides; Stereoisomerism; Structure-Activity Relationship; Tetrahydrofolates	1994
Synthesis and biological activity of 7-oxo substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid (5-DATHF) and 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF). Journal of medicinal chemistry, 2001, Jul-05, Volume: 44, Issue:14 Topics: Antineoplastic Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Escherichia coli; Folic Acid Antagonists; Humans; Hydroxymethyl and Formyl Transferases; Models, Molecular; Phosphoribosylglycinamide Formyltransferase; Ribonucleotides; Structure-Activity Relationship; Tetrahydrofolates; Tumor Cells, Cultured	2001

Article

Year

A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors.

Cancer research, 1994, Feb-15, Volume: 54, Issue:4

Topics: Acyltransferases; Animals; Antineoplastic Agents; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Folic Acid Antagonists; Humans; Hydroxymethyl and Formyl Transferases; Leukemia; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Phosphoribosylglycinamide Formyltransferase; Receptors, Cell Surface; Ribonucleotides; Stereoisomerism; Structure-Activity Relationship; Tetrahydrofolates

1994

Synthesis and biological activity of 7-oxo substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid (5-DATHF) and 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF).

Journal of medicinal chemistry, 2001, Jul-05, Volume: 44, Issue:14

Topics: Antineoplastic Agents; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Escherichia coli; Folic Acid Antagonists; Humans; Hydroxymethyl and Formyl Transferases; Models, Molecular; Phosphoribosylglycinamide Formyltransferase; Ribonucleotides; Structure-Activity Relationship; Tetrahydrofolates; Tumor Cells, Cultured

2001