glycerol and phenylacetylglutamine

glycerol has been researched along with phenylacetylglutamine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beliveau, M; Berry, SA; Diaz, GA; Dickinson, K; Gargosky, S; Lee, B; Marier, JF; Martinez, A; Mauney, J; Mian, A; Mokhtarani, M; Rhead, W; Scharschmidt, BF; Shchelochkov, O1
Bart, S; Bartholomew, D; Bartley, J; Berquist, W; Berry, SA; Cederbaum, S; Coakley, DF; Diaz, GA; Dickinson, K; Dorrani, N; Feigenbaum, A; Gallagher, R; Harding, CO; Korson, MS; Kronn, D; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; McCandless, SE; Merritt, JL; Mokhtarani, M; Moors, TL; Rhead, W; Scharschmidt, BF; Smith, W; Sreenath-Nagamani, S; Summar, M; Vockley, J; Zori, R1
Berry, SA; Coakley, DF; Diaz, GA; Dickinson, K; Harding, CO; Lee, B; LeMons, C; Lichter-Konecki, U; Mauney, J; McCandless, SE; Mokhtarani, M; Moors, T; Scharschmidt, BF; Smith, W1
Berry, SA; Coakley, D; Diaz, GA; Dickinson, K; Lee, B; Lemons, C; Lichter-Konecki, U; Mokhtarani, M; Monteleone, JP; Rhead, W; Scharschmidt, BF1
Alexeeva, O; Baranovsky, A; Bass, NM; Brown, RS; Coakley, D; Dickinson, K; Dudar, L; Fadieienko, G; Ghabril, M; Grewal, P; Grinevich, V; Kharchenko, N; Klaryts'ka, I; Mantry, P; McCashland, T; Mokhtarani, M; Morozov, V; Norris, C; Reddy, KG; Reddy, KR; Rockey, DC; Scharschmidt, BF; Syplyviy, V; Vierling, JM; Zupanets, IA1
Bartley, J; Berquist, W; Berry, SA; Brown, RS; Coakley, D; Diaz, GA; Dickinson, K; Feigenbaum, A; Gallagher, R; Ghabril, M; Harding, C; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; Mantry, P; McCandless, SE; Milikien, DA; Mokhtarani, M; Moors, T; Nagamani, SC; Norris, C; Rhead, W; Rockey, DC; Scharschmidt, BF; Schulze, A; Smith, W; Vierling, JM1
Almannai, M; Elsea, SH; Jiang, Y; Sun, Q; Sutton, VR1

Trials

4 trial(s) available for glycerol and phenylacetylglutamine

ArticleYear
Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: safety, pharmacokinetics and ammonia control.
    Molecular genetics and metabolism, 2010, Volume: 100, Issue:3

    Topics: Adult; Aged; Ammonia; Cross-Over Studies; Female; Glutamine; Glycerol; Humans; Male; Middle Aged; Phenylacetates; Phenylbutyrates; Urea Cycle Disorders, Inborn; Young Adult

2010
Urinary phenylacetylglutamine as dosing biomarker for patients with urea cycle disorders.
    Molecular genetics and metabolism, 2012, Volume: 107, Issue:3

    Topics: Adolescent; Adult; Ammonia; Biomarkers, Pharmacological; Child; Cross-Over Studies; Drug Administration Schedule; Female; Glutamine; Glycerol; Humans; Male; Phenylacetates; Phenylbutyrates; Urea Cycle Disorders, Inborn

2012
Ammonia control in children ages 2 months through 5 years with urea cycle disorders: comparison of sodium phenylbutyrate and glycerol phenylbutyrate.
    The Journal of pediatrics, 2013, Volume: 162, Issue:6

    Topics: Ammonia; Child; Child, Preschool; Drug Substitution; Female; Glutamine; Glycerol; Humans; Infant; Liver; Male; Phenylbutyrates; Surveys and Questionnaires; Urea Cycle Disorders, Inborn

2013
Randomized, double-blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy.
    Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:3

    Topics: Adult; Aged; Ammonia; Double-Blind Method; Female; Glutamine; Glycerol; Hepatic Encephalopathy; Humans; Hyperammonemia; Male; Middle Aged; Phenylbutyrates; Treatment Outcome; Urea; Young Adult

2014

Other Studies

3 other study(ies) available for glycerol and phenylacetylglutamine

ArticleYear
Population pharmacokinetic modeling and dosing simulations of nitrogen-scavenging compounds: disposition of glycerol phenylbutyrate and sodium phenylbutyrate in adult and pediatric patients with urea cycle disorders.
    Journal of clinical pharmacology, 2013, Volume: 53, Issue:7

    Topics: Adult; Child; Child, Preschool; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Computer Simulation; Female; Glutamine; Glycerol; Humans; Male; Models, Biological; Nitrogen; Phenylbutyrates; Randomized Controlled Trials as Topic; Rare Diseases; Urea Cycle Disorders, Inborn

2013
Elevated phenylacetic acid levels do not correlate with adverse events in patients with urea cycle disorders or hepatic encephalopathy and can be predicted based on the plasma PAA to PAGN ratio.
    Molecular genetics and metabolism, 2013, Volume: 110, Issue:4

    Topics: Biomarkers; Drug-Related Side Effects and Adverse Reactions; Glutamine; Glycerol; Hepatic Encephalopathy; Humans; Liver; Neoplasms; Phenylacetates; Phenylbutyrates; Randomized Controlled Trials as Topic; Urea Cycle Disorders, Inborn

2013
Quantitation of phenylbutyrate metabolites by UPLC-MS/MS demonstrates inverse correlation of phenylacetate:phenylacetylglutamine ratio with plasma glutamine levels.
    Molecular genetics and metabolism, 2017, Volume: 122, Issue:3

    Topics: Ammonia; Argininosuccinic Aciduria; Chromatography, Liquid; Female; Glutamine; Glycerol; Humans; Limit of Detection; Male; Middle Aged; Ornithine Carbamoyltransferase Deficiency Disease; Phenylacetates; Phenylbutyrates; Tandem Mass Spectrometry; Urea; Urea Cycle Disorders, Inborn

2017