glycerol and glycerol phenylbutyrate

glycerol has been researched along with glycerol phenylbutyrate in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	22 (84.62)	24.3611
2020's	4 (15.38)	2.80

Authors

Authors	Studies
Beliveau, M; Diaz, GA; Dickinson, K; Feigenbaum, A; Jomphe, C; Lichter-Konecki, U; Marier, JF; Martinez, A; Mauney, J; Merritt, JL; Mokhtarani, M; Rhead, W; Scharschmidt, B	1
Bart, S; Bartholomew, D; Bartley, J; Berquist, W; Berry, SA; Cederbaum, S; Coakley, DF; Diaz, GA; Dickinson, K; Dorrani, N; Feigenbaum, A; Gallagher, R; Harding, CO; Korson, MS; Kronn, D; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; McCandless, SE; Merritt, JL; Mokhtarani, M; Moors, TL; Rhead, W; Scharschmidt, BF; Smith, W; Sreenath-Nagamani, S; Summar, M; Vockley, J; Zori, R	1
Bart, SA; Bartholomew, D; Bartley, J; Berquist, W; Berry, SA; C S Nagamani, S; Cederbaum, S; Coakley, DF; Diaz, GA; Dickinson, K; Feigenbaum, A; Gallagher, R; Harding, CO; Korson, MS; Krivitzky, LS; Kronn, D; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; Mauney, J; McCandless, SE; Merritt, JL; Mokhtarani, M; Moors, TL; Rhead, W; Scharschmidt, BF; Smith, W; Vockley, G; Zori, R	1
Mistry, PK	1
Berry, SA; Coakley, DF; Diaz, GA; Dickinson, K; Harding, CO; Lee, B; LeMons, C; Lichter-Konecki, U; Mauney, J; McCandless, SE; Mokhtarani, M; Moors, T; Scharschmidt, BF; Smith, W	1
Guha, M	1
Berry, SA; Coakley, D; Diaz, GA; Dickinson, K; Lee, B; Lemons, C; Lichter-Konecki, U; Mokhtarani, M; Monteleone, JP; Rhead, W; Scharschmidt, BF	1
Alexeeva, O; Baranovsky, A; Bass, NM; Brown, RS; Coakley, D; Dickinson, K; Dudar, L; Fadieienko, G; Ghabril, M; Grewal, P; Grinevich, V; Kharchenko, N; Klaryts'ka, I; Mantry, P; McCashland, T; Mokhtarani, M; Morozov, V; Norris, C; Reddy, KG; Reddy, KR; Rockey, DC; Scharschmidt, BF; Syplyviy, V; Vierling, JM; Zupanets, IA	1
Córdoba, J; Ventura-Cots, M	1
Bartley, J; Berquist, W; Berry, SA; Brown, RS; Coakley, D; Diaz, GA; Dickinson, K; Feigenbaum, A; Gallagher, R; Ghabril, M; Harding, C; Lee, B; Lemons, C; Lichter-Konecki, U; Longo, N; Mantry, P; McCandless, SE; Milikien, DA; Mokhtarani, M; Moors, T; Nagamani, SC; Norris, C; Rhead, W; Rockey, DC; Scharschmidt, BF; Schulze, A; Smith, W; Vierling, JM	1
Jalan, R; Jover-Cobos, M; Khetan, V	1
Rahimi, RS; Rockey, DC	1
Sussman, NL	1
Cross, TJ; Ellul, MA; Gholkar, SA	1
Bartley, J; Berquist, W; Berry, SA; Coakley, DF; Diaz, GA; Feigenbaum, A; Gallagher, RC; Harding, CO; Le Mons, C; Lee, B; Lichter-Konecki, U; Longo, N; Marino, M; McCandless, SE; Mokhtarani, M; Nagamani, SC; Rhead, W; Rowell, R; Scharschmidt, BF; Schulze, A; Smith, W	1
Almannai, M; Elsea, SH; Jiang, Y; Sun, Q; Sutton, VR	1
Berry, SA; Diaz, GA; Ficicioglu, C; Harding, CO; Lichter-Konecki, U; Longo, N; McCandless, SE; Robinson, B; Smith, WE; Vockley, J; Zori, R	1
Berry, SA; Diaz, GA; Dong, M; Ficicioglu, C; Harding, CO; Holt, RJ; Lichter-Konecki, U; Longo, N; McCandless, SE; Perdok, R; Robinson, B; Smith, WE; Vinks, AA; Vockley, J; Zori, R	1
Alsahhar, JS; Rahimi, RS	1
Baumgartner, MR; Bedoyan, JK; Berry, GT; Burgard, P; Burrage, LC; Garbade, SF; Garcia-Cazorla, A; Gropman, AL; Hoffmann, GF; Kölker, S; McCandless, SE; Nagamani, SCS; Posset, R; Schulze, A; Seminara, J; Wong, D; Yudkoff, M; Zielonka, M	1
Bartholomew, D; Berquist, W; Berry, SA; Canavan, C; Diaz, GA; Feigenbaum, A; Gallagher, RC; Harding, CO; Holt, RJ; Lichter-Konecki, U; Longo, N; McCandless, SE; Merritt, JL; Rhead, W; Schulze, A; Smith, WE; Vescio, T; Vockley, J; Wong, D; Zori, R	1
Mahpour, NY; Pioppo-Phelan, L; Reja, M; Rustgi, VK; Tawadros, A	1
Alimirah, M; Gordon, SC; Sadiq, O	1
Almes, M; Gonzales, E; Jacquemin, E; Jobert, A; Lapalus, M; Mareux, E	1
Ah Mew, N; Bannick, AA; Berry, SA; Canavan, C; Conway, RL; Diaz, GA; Hainline, B; Inbar-Feigenberg, M; Kok, T; Lichter-Konecki, U; Longo, N; McCandless, SE; Porter, MH; Schulze, A; Vescio, T; Zori, R	1

Reviews

8 review(s) available for glycerol and glycerol phenylbutyrate

Article	Year
Treatment of hyperammonemia in liver failure. Current opinion in clinical nutrition and metabolic care, 2014, Volume: 17, Issue:1 Topics: Ammonia; Brain; Glycerol; Hepatic Encephalopathy; Humans; Hyperammonemia; Lactulose; Phenylbutyrates; Probiotics; Randomized Controlled Trials as Topic; Rifamycins; Rifaximin	2014
Glycerol phenylbutyrate (Ravicti) for urea cycle disorders. The Medical letter on drugs and therapeutics, 2014, Aug-18, Volume: 56, Issue:1449 Topics: Animals; Glycerol; Humans; Phenylbutyrates; Randomized Controlled Trials as Topic; Urea Cycle Disorders, Inborn	2014
Novel Ammonia-Lowering Agents for Hepatic Encephalopathy. Clinics in liver disease, 2015, Volume: 19, Issue:3 Topics: Ammonia; Carbon; Gastrointestinal Agents; Glycerol; Hepatic Encephalopathy; Humans; Ornithine; Oxides; Phenylbutyrates; Polyethylene Glycols; Urea	2015
Treatment of Overt Hepatic Encephalopathy. Clinics in liver disease, 2015, Volume: 19, Issue:3 Topics: Amino Acids, Branched-Chain; Ammonia; Arteriovenous Fistula; Dipeptides; Gastrointestinal Agents; Glycerol; Hepatic Encephalopathy; Humans; Lactulose; Liver Failure; Malnutrition; Ornithine; Phenylbutyrates; Probiotics; Rifamycins; Rifaximin	2015
Hepatic encephalopathy due to liver cirrhosis. BMJ (Clinical research ed.), 2015, Aug-11, Volume: 351 Topics: Albumins; Amino Acids; Diagnosis, Differential; Diet; Disaccharides; Drug Resistance; Electroencephalography; Glycerol; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Magnetic Resonance Imaging; Neomycin; Neurologic Examination; Nucleic Acid Synthesis Inhibitors; Ornithine; Phenylbutyrates; Probiotics; Protein Synthesis Inhibitors; Rifamycins; Rifaximin; Terminal Care; Tomography, X-Ray Computed	2015
Updates on the pathophysiology and therapeutic targets for hepatic encephalopathy. Current opinion in gastroenterology, 2019, Volume: 35, Issue:3 Topics: Amino Acids, Aromatic; Amino Acids, Branched-Chain; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Frailty; Gastrointestinal Agents; Gastrointestinal Microbiome; Glycerol; Hepatic Encephalopathy; Humans; Hypertension, Portal; Lactulose; Liver Cirrhosis; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Rifaximin; Trace Elements; Zinc	2019
Pharmacologic Management of Hepatic Encephalopathy. Clinics in liver disease, 2020, Volume: 24, Issue:2 Topics: Acarbose; Amino Acids, Branched-Chain; Anti-Bacterial Agents; Dipeptides; Fecal Microbiota Transplantation; Flumazenil; GABA Modulators; Glycerol; Glycoside Hydrolase Inhibitors; Hepatic Encephalopathy; Humans; Lactulose; Laxatives; Phenylbutyrates; Probiotics; Rifaximin	2020
Novel Therapies in Hepatic Encephalopathy. Clinics in liver disease, 2020, Volume: 24, Issue:2 Topics: Acetylcarnitine; Albumins; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Flumazenil; GABA Modulators; Glycerol; Hepatic Encephalopathy; Humans; Nootropic Agents; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Surface-Active Agents	2020

Trials

6 trial(s) available for glycerol and glycerol phenylbutyrate

Article	Year
Ammonia control in children with urea cycle disorders (UCDs); phase 2 comparison of sodium phenylbutyrate and glycerol phenylbutyrate. Molecular genetics and metabolism, 2011, Volume: 103, Issue:4 Topics: Adolescent; Ammonia; Child; Dose-Response Relationship, Drug; Glycerol; Humans; Male; Phenylbutyrates; Urea; Urea Cycle Disorders, Inborn	2011
Urinary phenylacetylglutamine as dosing biomarker for patients with urea cycle disorders. Molecular genetics and metabolism, 2012, Volume: 107, Issue:3 Topics: Adolescent; Adult; Ammonia; Biomarkers, Pharmacological; Child; Cross-Over Studies; Drug Administration Schedule; Female; Glutamine; Glycerol; Humans; Male; Phenylacetates; Phenylbutyrates; Urea Cycle Disorders, Inborn	2012
Ammonia control and neurocognitive outcome among urea cycle disorder patients treated with glycerol phenylbutyrate. Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:6 Topics: Adolescent; Adult; Ammonia; Child; Cross-Over Studies; Double-Blind Method; Female; Glutamine; Glycerol; Humans; Male; Middle Aged; Neuropsychological Tests; Phenylbutyrates; Urea Cycle Disorders, Inborn; Young Adult	2013
Ammonia control in children ages 2 months through 5 years with urea cycle disorders: comparison of sodium phenylbutyrate and glycerol phenylbutyrate. The Journal of pediatrics, 2013, Volume: 162, Issue:6 Topics: Ammonia; Child; Child, Preschool; Drug Substitution; Female; Glutamine; Glycerol; Humans; Infant; Liver; Male; Phenylbutyrates; Surveys and Questionnaires; Urea Cycle Disorders, Inborn	2013
Randomized, double-blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy. Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:3 Topics: Adult; Aged; Ammonia; Double-Blind Method; Female; Glutamine; Glycerol; Hepatic Encephalopathy; Humans; Hyperammonemia; Male; Middle Aged; Phenylbutyrates; Treatment Outcome; Urea; Young Adult	2014
Glutamine and hyperammonemic crises in patients with urea cycle disorders. Molecular genetics and metabolism, 2016, Volume: 117, Issue:1 Topics: Adolescent; Adult; Ammonia; Biomarkers; Child; Child, Preschool; Fasting; Female; Glutamine; Glycerol; Humans; Hyperammonemia; Male; Phenylbutyrates; Predictive Value of Tests; Urea Cycle Disorders, Inborn; Young Adult	2016

Other Studies

12 other study(ies) available for glycerol and glycerol phenylbutyrate

Article	Year
Rare disease clinical research network's urea cycle consortium delivers a successful clinical trial to improve alternate pathway therapy. Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:6 Topics: Ammonia; Female; Glycerol; Humans; Male; Phenylbutyrates; Urea Cycle Disorders, Inborn	2013
Urea cycle disorder drug approved. Nature biotechnology, 2013, Volume: 31, Issue:4 Topics: Adult; Clinical Trials as Topic; Drug Approval; Drug Industry; Glycerol; Humans; Patient Compliance; Phenylbutyrates; Urea Cycle Disorders, Inborn	2013
Population pharmacokinetic modeling and dosing simulations of nitrogen-scavenging compounds: disposition of glycerol phenylbutyrate and sodium phenylbutyrate in adult and pediatric patients with urea cycle disorders. Journal of clinical pharmacology, 2013, Volume: 53, Issue:7 Topics: Adult; Child; Child, Preschool; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Computer Simulation; Female; Glutamine; Glycerol; Humans; Male; Models, Biological; Nitrogen; Phenylbutyrates; Randomized Controlled Trials as Topic; Rare Diseases; Urea Cycle Disorders, Inborn	2013
Drug-induced removal of nitrogen derivatives in urine: a new concept whose time has come. Hepatology (Baltimore, Md.), 2014, Volume: 59, Issue:3 Topics: Ammonia; Female; Glycerol; Hepatic Encephalopathy; Humans; Hyperammonemia; Male; Phenylbutyrates	2014
Elevated phenylacetic acid levels do not correlate with adverse events in patients with urea cycle disorders or hepatic encephalopathy and can be predicted based on the plasma PAA to PAGN ratio. Molecular genetics and metabolism, 2013, Volume: 110, Issue:4 Topics: Biomarkers; Drug-Related Side Effects and Adverse Reactions; Glutamine; Glycerol; Hepatic Encephalopathy; Humans; Liver; Neoplasms; Phenylacetates; Phenylbutyrates; Randomized Controlled Trials as Topic; Urea Cycle Disorders, Inborn	2013
Quantitation of phenylbutyrate metabolites by UPLC-MS/MS demonstrates inverse correlation of phenylacetate:phenylacetylglutamine ratio with plasma glutamine levels. Molecular genetics and metabolism, 2017, Volume: 122, Issue:3 Topics: Ammonia; Argininosuccinic Aciduria; Chromatography, Liquid; Female; Glutamine; Glycerol; Humans; Limit of Detection; Male; Middle Aged; Ornithine Carbamoyltransferase Deficiency Disease; Phenylacetates; Phenylbutyrates; Tandem Mass Spectrometry; Urea; Urea Cycle Disorders, Inborn	2017
Safety and efficacy of glycerol phenylbutyrate for management of urea cycle disorders in patients aged 2months to 2years. Molecular genetics and metabolism, 2017, Volume: 122, Issue:3 Topics: Ammonia; Child, Preschool; Cough; Disease Management; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Glutamine; Glycerol; Humans; Infant; Male; Neutropenia; Phenylbutyrates; Prospective Studies; Retrospective Studies; Urea Cycle Disorders, Inborn	2017
Pharmacokinetics of glycerol phenylbutyrate in pediatric patients 2 months to 2 years of age with urea cycle disorders. Molecular genetics and metabolism, 2018, Volume: 125, Issue:3 Topics: Child; Child, Preschool; Female; Glutamine; Glycerol; Humans; Infant; Lipase; Male; Nitrogen; Phenylacetates; Phenylbutyrates; Prodrugs; Urea Cycle Disorders, Inborn	2018
Impact of Diagnosis and Therapy on Cognitive Function in Urea Cycle Disorders. Annals of neurology, 2019, Volume: 86, Issue:1 Topics: Adolescent; Adult; Child; Child, Preschool; Cognition; Cross-Sectional Studies; Female; Follow-Up Studies; Glycerol; Humans; Infant; Infant, Newborn; Liver Transplantation; Male; Mental Status and Dementia Tests; Neonatal Screening; Phenylbutyrates; Prospective Studies; Urea Cycle Disorders, Inborn; Young Adult	2019
Long-term safety and efficacy of glycerol phenylbutyrate for the management of urea cycle disorder patients. Molecular genetics and metabolism, 2019, Volume: 127, Issue:4 Topics: Adolescent; Adult; Canada; Child; Child, Preschool; Disease Management; Female; Follow-Up Studies; Glycerol; Humans; Hyperammonemia; Infant; Male; Middle Aged; Neuropsychological Tests; Phenylbutyrates; United States; Urea Cycle Disorders, Inborn; Young Adult	2019
Glycerol Phenylbutyrate Therapy in Progressive Familial Intrahepatic Cholestasis Type 2. Journal of pediatric gastroenterology and nutrition, 2020, Volume: 70, Issue:6 Topics: Cholestasis, Intrahepatic; Glycerol; Humans; Phenylbutyrates	2020
Glycerol phenylbutyrate efficacy and safety from an open label study in pediatric patients under 2 months of age with urea cycle disorders. Molecular genetics and metabolism, 2021, Volume: 132, Issue:1 Topics: Age of Onset; Ammonia; Child, Preschool; Female; Glycerol; Humans; Hyperammonemia; Infant; Infant, Newborn; Male; Pediatrics; Phenylacetates; Phenylbutyrates; Renal Dialysis; Urea Cycle Disorders, Inborn	2021