glycerol has been researched along with cyclosporine in 58 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 25 (43.10) | 18.2507 |
2000's | 24 (41.38) | 29.6817 |
2010's | 9 (15.52) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Ilhan, M; Tuncer, M; Yaris, E | 1 |
Chester, A; Mankad, P; O'Neil, G; Slavik, Z; Spatenka, J; Yacoub, M | 1 |
Brat, DJ; Brimijoin, S; Windebank, AJ | 1 |
Yee, GC | 1 |
Beliveau, R; Jetté, L; Leclerc, JM; Murphy, GF | 1 |
Chan, HS; Doyle, J; Greenberg, ML; Koren, G; Liau-Chu, M; Theis, JG | 1 |
Osann, K; Slater, L; Stupecky, M; Sweet, P; Wetzel, M | 1 |
Buckels, J; Cramb, R; Dousset, B; Krentz, AJ; Mayer, D; McMaster, P; Nattrass, M; Smith, JM | 1 |
Tuncer, M; Yaris, E | 1 |
Baker, RM; Brecher, ML; Chervinsky, DS; Hoelcle, MJ; Tebbi, CK | 1 |
Lodge, NJ | 1 |
Blexrud, MD; de Groen, PC; Windebank, AJ | 1 |
Cornblatt, B; Lee, EJ; Levy, C; Ross, DD; Schiffer, CA; Sridhara, R; Tong, Y; Wooten, PJ | 1 |
Alvestrand, A; Larsson, M; Tibell, A | 1 |
Ge, X; McCarthy, ET; Savin, VJ; Sharma, M; Sharma, R | 1 |
Baliga, R; Shah, SV; Ueda, N; Walker, PD | 2 |
Windebank, AJ | 1 |
Dahlback, M; Eirefelt, S; Karlsson, BW; Lundin, PD; Pierzynowski, SG; Podlesny, J; Siwinska-Golebiowska, H; Taljanski, W; Westrom, BR | 1 |
Brinkmann, T; Kleesiek, K; Körfer, R; Körner, M; Prohaska, W; Tiemann, C | 1 |
Koren, G; Liau-Chu, M; Theis, JG | 1 |
Michaud, LB | 1 |
Canada, AL; Ross, HJ; Slater, LM | 1 |
Hoshino, N; Minouchi, T; Ohmae, T; Shibata, N; Yamaji, A | 1 |
Heitman, J; Joseph, JD; Means, AR | 1 |
Escousse, A; Gouyon, JB; Guignard, JP; Justrabo, E; Prévot, A; Semama, DS | 1 |
Cloarec, A; Cornaire, G; Decourt, S; Houin, G; Legendre, JY; Saivin, S; Woodley, JF | 1 |
Huang, ZH; Murakami, T; Nagai, J; Okochi, A; Takano, M; Yumoto, R | 1 |
Bessard, G; Deveaux, G; Devillier, P; Hardy, G; Sessa, C; Stanke-Labesque, F | 1 |
Sparreboom, A; van Zuylen, L; Verweij, J | 1 |
Meyer, D; van der Bijl, P; van Eyk, AD | 1 |
Andoh, T; Bennett, WM; Zager, RA | 1 |
Barnes, AD; Buckels, JA; Dmitrewski, J; Krentz, AJ; Mayer, AD; Nattrass, M; Smith, J | 1 |
Bardelmeijer, HA; Beijnen, JH; Koopman, FJ; Malingré, MM; Ouwehand, M; Rosing, H; Schellens, JH; Schot, ME; Ten Bokkel Huinink, WW; Van Tellingen, O | 1 |
Engelbrecht, AH; Meyer, D; Van Der Bijl, P; Van Eyk, AD | 1 |
Beijnen, JH; Boogerd, W; Cleypool, C; Kemper, EM; Mos, HA; van Tellingen, O; van Zandbergen, AE | 1 |
Dyck, J; English, D; Kerjner, A; Lai, JC; Loo, S; McDonald, PC; McManus, BM; Moghadasian, MH; Tranfield, EM; Walker, DC; Wilson, JE; Wong, D | 1 |
Chang, EJ; Mun, KC | 1 |
Imashuku, S; Imoto, S; Koizumi, T; Mizuno, I; Murayama, T; Sada, A; Yakushijin, K | 1 |
Furukawa, H; Ishizaki, J; Jin, M; Miyamoto, K; Mizuhara, Y; Nomura, M; Shimada, T; Yokogawa, K | 1 |
Donnenfeld, ED; Greenman, HE; Perry, HD; Solomon, R | 1 |
Aliabadi, HM; Lavasanifar, A; Mahmud, A; Sharifabadi, AD | 1 |
Connor, HD; Forman, DT; Lemasters, JJ; Li, X; Mason, RP; Thurman, RG; Zhong, Z | 1 |
Italia, JL; Ravi Kumar, MN; Sharma, G; Sonaje, K; Tikoo, K | 1 |
Andrysek, T | 1 |
Cantero, PD; Ernst, JF; Lengsfeld, C; Pla, J; Prill, SK; Román, E; Subanović, M | 1 |
Chen, JS; Chen, PM; Chu, Z; Figg, WD; Gardner, ER; Liau, CT; Lin, YC; Sparreboom, A; Wang, HM; Yang, MH | 1 |
Gan, L; Gan, Y; Zhang, X; Zhu, C; Zhu, J | 1 |
Annapure, US; Singhal, RS; Survase, SA | 1 |
Atilla, P; Bolay, H; Cakar, AN; Dalkara, T; Emre-Aydıngöz, S; Erdem, SR; Tuncer, M | 1 |
Aït-Slimane, T; Delaunay, JL; Delautier, D; Durand-Schneider, AM; Gabillet, J; Gautherot, J; Housset, C; Maurice, M; Rada, A | 1 |
Aldouby, YH; Avramoff, A; Domb, AJ; Khan, W | 1 |
Dufour, S; Geny, B; Kindo, M; Lampert, E; Mettauer, B; N' Guessan, BB; Ribera, F; Sanchez, H; Ventura-Clapier, R; Zoll, J | 1 |
Aureliano, M; Carvalho, E; Eriksson, JW; Palming, J; Pereira, MJ; Rizell, M; Svensson, MK | 1 |
Ehinger, KH; Elmér, E; Hansson, MJ; Sjövall, F | 1 |
Adriaensens, P; Carleer, R; Hermans, K; Kerimova, S; Ludwig, A; Van den Plas, D; Weyenberg, W | 1 |
Ashraf, M; Choi, S; Cruz, CN; Dong, Y; Hengst, L; Hunt, R; Patel, D; Vo, A; Xu, X | 1 |
5 review(s) available for glycerol and cyclosporine
Article | Year |
---|---|
Dosage forms of cyclosporine.
Topics: Administration, Oral; Capsules; Cyclosporine; Drug Stability; Glycerol; Humans; Injections, Intravenous; Solutions | 1991 |
Oxidant mechanisms in toxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Cyclosporine; Free Radicals; Gentamicins; Glycerol; Humans; Immunosuppressive Agents; Oxidants; Reactive Oxygen Species | 1997 |
Methods for preventing reactions secondary to Cremophor EL.
Topics: Anaphylaxis; Chemistry, Pharmaceutical; Cyclosporine; Drug Compounding; Glycerol; Humans; Pharmaceutical Vehicles | 1997 |
Oxidant mechanisms in toxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Cryoprotective Agents; Cyclosporine; Gentamicins; Glycerol; Hydrogen Peroxide; Immunosuppressive Agents; Oxidants; Rats; Reactive Oxygen Species | 1999 |
Role of formulation vehicles in taxane pharmacology.
Topics: Animals; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chemistry, Pharmaceutical; Cyclosporine; Drug Hypersensitivity; Drug Resistance, Multiple; Glycerol; Humans; Micelles; Neoplasms; Nervous System Diseases; Paclitaxel; Polysorbates; Surface-Active Agents | 2001 |
7 trial(s) available for glycerol and cyclosporine
Article | Year |
---|---|
Anaphylactoid reactions in children receiving high-dose intravenous cyclosporine for reversal of tumor resistance: the causative role of improper dissolution of Cremophor EL.
Topics: Adolescent; Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Azo Compounds; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Ethanol; Glycerol; Humans; Immunosuppressive Agents; Infusions, Intravenous; Pharmaceutical Vehicles; Premedication; Rhabdomyosarcoma; Solubility; Solvents; Statistics, Nonparametric | 1995 |
Metabolic effects of cyclosporin A and FK 506 in liver transplant recipients.
Topics: Analysis of Variance; Azathioprine; Blood Glucose; Body Mass Index; C-Peptide; Cyclosporine; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Glycerol; Humans; Insulin; Ketone Bodies; Lactates; Liver Transplantation; Male; Middle Aged; Prospective Studies; Pyruvates; Pyruvic Acid; Reference Values; Tacrolimus | 1993 |
Metabolic and hormonal effects of tacrolimus (FK506) or cyclosporin immunosuppression following renal transplantation.
Topics: Alanine; Blood Glucose; C-Peptide; Cyclosporine; Fatty Acids, Nonesterified; Follow-Up Studies; Glucose Tolerance Test; Glycerol; Humans; Immunosuppressive Agents; Insulin; Insulin Resistance; Insulin Secretion; Ketone Bodies; Kidney Transplantation; Lactates; Postprandial Period; Pyruvates; Reference Values; Tacrolimus; Time Factors | 2001 |
The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients.
Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Area Under Curve; Cyclosporine; Drug Combinations; Feces; Glycerol; Humans; Intestinal Absorption; Neoplasms; Paclitaxel; Pharmaceutical Vehicles; Polysorbates; Solvents | 2001 |
Oral bioavailability of a novel paclitaxel formulation (Genetaxyl) administered with cyclosporin A in cancer patients.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Availability; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycerol; Humans; Immunosuppressive Agents; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Paclitaxel | 2008 |
Oxidative capacities of cardiac and skeletal muscles of heart transplant recipients: mitochondrial effects of cyclosporin-A and its vehicle Cremophor-EL.
Topics: Cyclosporine; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Chain Complex Proteins; Female; Glycerol; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Mitochondria, Heart; Mitochondria, Muscle; Muscle, Skeletal; Myocardium; Oxygen Consumption; Pharmaceutical Vehicles; Transplants | 2014 |
Bioequivalence and tolerability assessment of a novel intravenous ciclosporin lipid emulsion compared to branded ciclosporin in Cremophor ® EL.
Topics: Adolescent; Adult; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Cyclosporine; Emulsifying Agents; Excipients; Fat Emulsions, Intravenous; Female; Glycerol; Half-Life; Humans; Immunosuppressive Agents; Infusions, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; South Africa; Therapeutic Equivalency; Young Adult | 2013 |
46 other study(ies) available for glycerol and cyclosporine
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Actions of cyclosporin A preparation and Cremophor-EL in rabbit mesenteric artery and thoracic aorta in vitro.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclosporine; Drug Synergism; Glycerol; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Solvents; Vasoconstriction; Vasodilation | 1992 |
Acute effects of cyclosporin and cremophor EL on endothelial function and vascular smooth muscle in the isolated rat heart.
Topics: Animals; Coronary Circulation; Cyclosporine; Endothelium, Vascular; Glycerol; Heart; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Perfusion; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains | 1992 |
Emulsifier for intravenous cyclosporin inhibits neurite outgrowth, causes deficits in rapid axonal transport and leads to structural abnormalities in differentiating N1E.115 neuroblastoma.
Topics: Animals; Cell Differentiation; Cyclosporine; Glycerol; Mice; Neurites; Neuroblastoma; Pharmaceutical Vehicles; Tumor Cells, Cultured; Video Recording | 1992 |
Interaction of drugs with P-glycoprotein in brain capillaries.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blood-Brain Barrier; Brain; Capillaries; Cyclosporine; Cyclosporins; Drug Interactions; Glycerol; In Vitro Techniques; Iodine Radioisotopes; Male; Prazosin; Rats; Rats, Sprague-Dawley; Time Factors; Tritium | 1995 |
Comparison of cyclosporin A, verapamil, PSC-833 and cremophor EL as enhancing agents of VP-16 in murine lymphoid leukemias.
Topics: Animals; Cell Survival; Cyclosporine; Cyclosporins; Drug Synergism; Etoposide; Glycerol; Leukemia L1210; Leukemia P388; Mice; Survival Analysis; Tumor Cells, Cultured; Verapamil | 1995 |
The effect of indomethacin on cyclosporin A- and its solvent-induced inhibition of endothelium-dependent relaxation and the drug-induced contraction of rabbit isolated arteries.
Topics: Acetylcholine; Animals; Cyclosporine; Endothelium, Vascular; Glycerol; In Vitro Techniques; Indomethacin; Male; Pharmaceutical Vehicles; Rabbits; Vasoconstriction; Vasodilation | 1995 |
Reversal of C1300 murine neuroblastoma multidrug resistance by cremophorEL, a solvent for cyclosporin A.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Chromatography, High Pressure Liquid; Clone Cells; Cyclosporine; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Glycerol; Harringtonines; Homoharringtonine; Intracellular Fluid; Mice; Neuroblastoma; Pharmaceutical Vehicles; Solvents; Tumor Cells, Cultured | 1993 |
Direct vasoconstrictor effects of sandimmune (cyclosporine A) are mediated by its vehicle cremophor EL: inhibition by the thromboxane A2/prostaglandin endoperoxide receptor antagonist ifetroban.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclosporine; Dose-Response Relationship, Drug; Glyburide; Glycerol; In Vitro Techniques; Male; Oxazoles; Pharmaceutical Vehicles; Propionates; Rabbits; Receptors, Thromboxane; Ricinoleic Acids; Vasoconstrictor Agents | 1994 |
Potential neurotoxicity of the solvent vehicle for cyclosporine.
Topics: Animals; Cyclosporine; Demyelinating Diseases; Ethanol; Female; Ganglia, Spinal; Glycerol; Humans; Nervous System; Pharmaceutical Vehicles; Pregnancy; Rats; Rats, Sprague-Dawley | 1994 |
Synergistic reversal of multidrug-resistance phenotype in acute myeloid leukemia cells by cyclosporin A and cremophor EL.
Topics: Cell Survival; Cyclosporine; Daunorubicin; Drug Resistance; Drug Synergism; Female; Glycerol; Humans; Leukemia, Myeloid, Acute; Male; Tumor Cells, Cultured | 1994 |
Dissolving intravenous cyclosporin A in a fat emulsion carrier prevents acute renal side effects in the rat.
Topics: Animals; Cyclosporine; Drug Carriers; Emulsions; Glomerular Filtration Rate; Glycerol; Infusions, Intravenous; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; Solubility; Soybean Oil | 1993 |
Cyclosporine protects glomeruli from FSGS factor via an increase in glomerular cAMP.
Topics: Albumins; Animals; Cyclic AMP; Cyclosporine; Glomerulosclerosis, Focal Segmental; Glycerol; Humans; Kidney Glomerulus; Male; Microscopy, Electron; Permeability; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1996 |
The vehicle for cyclosporine is neurotoxic in vitro.
Topics: Animals; Axons; Cells, Cultured; Cyclosporine; Demyelinating Diseases; Glycerol; Humans; Neurons; Oligodendroglia; Pharmaceutical Vehicles | 1997 |
Pulmonary delivery of intratracheally instilled and aerosolized cyclosporine A to young and adult rats.
Topics: Aerosols; Aging; Animals; Biological Availability; Cyclosporine; Female; Glycerol; Half-Life; Lung; Male; Rats; Rats, Sprague-Dawley; Trachea | 1997 |
Effect of cyclosporine A on the release of tissue factor pathway inhibitor from endothelial cells in heart transplant patients and cell culture.
Topics: Adolescent; Adult; Calcimycin; Calcium; Cell Division; Cells, Cultured; Cyclosporine; Endothelium, Vascular; Female; Glycerol; Heart Transplantation; Humans; Ionophores; Lipoproteins; Male; Middle Aged; Pharmaceutical Vehicles; von Willebrand Factor | 1997 |
Mechanism of anaphylactoid reactions: improper preparation of high-dose intravenous cyclosporine leads to bolus infusion of Cremophor EL and cyclosporine.
Topics: Anaphylaxis; Chemistry, Pharmaceutical; Cyclosporine; Drug Compounding; Ethanol; Glycerol; Humans; Pharmaceutical Vehicles; Solutions | 1997 |
Cyclosporin A enhances paclitaxel toxicity against leukemia and respiratory epithelial cancers.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Cytokines; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Glycerol; Growth Substances; Humans; Immunosuppressive Agents; Leukemia; Mice; Paclitaxel; Respiratory Tract Neoplasms; Survival Rate; Treatment Outcome; Tumor Cells, Cultured | 1997 |
Influence of glycerol-induced acute renal failure on the pharmacokinetics of cyclosporin in rats.
Topics: Acetaminophen; Acute Kidney Injury; Administration, Oral; Analgesics, Non-Narcotic; Animals; Area Under Curve; Blood Urea Nitrogen; Creatine; Cyclosporine; Gastric Emptying; Glycerol; Ileum; Immunosuppressive Agents; In Vitro Techniques; Injections, Intravenous; Jejunum; Liver; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Molecular cloning and characterization of Aspergillus nidulans cyclophilin B.
Topics: Amino Acid Sequence; Animals; Antifungal Agents; Aspergillus nidulans; Base Sequence; Calcineurin; Cattle; Cloning, Molecular; Culture Media; Cyclophilins; Cyclosporine; DNA, Fungal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Glycerol; Hot Temperature; Immunophilins; Microbial Sensitivity Tests; Molecular Sequence Data; Peptidylprolyl Isomerase; Recombinant Fusion Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Threonine | 1999 |
Acute cyclosporine A-induced nephrotoxicity: a rabbit model.
Topics: Acute Disease; Animals; Cyclosporine; Glycerol; Kidney; Kidney Diseases; Male; Rabbits; Renal Circulation; Surface-Active Agents | 2000 |
Effect of polyoxyl 35 castor oil and Polysorbate 80 on the intestinal absorption of digoxin in vitro.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiotonic Agents; Cyclosporine; Digoxin; Glycerol; In Vitro Techniques; Intestinal Absorption; Intestine, Small; L-Lactate Dehydrogenase; Micelles; Polysorbates; Rats; Surface-Active Agents | 2000 |
Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Brain Chemistry; Caco-2 Cells; Cyclosporine; Glycerol; Humans; Kidney; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Wistar; Rhodamine 123 | 2000 |
Cyclosporine A and cremophor EL induce contractions of human saphenous vein: involvement of thromboxane A2 receptor-dependent pathway.
Topics: Biphenyl Compounds; Cyclosporine; Fibrinolytic Agents; Glycerol; Heptanoic Acids; Humans; Immunosuppressive Agents; In Vitro Techniques; Lipoxygenase Inhibitors; Muscle Contraction; Muscle, Smooth, Vascular; Pharmaceutical Vehicles; Receptors, Thromboxane; Saphenous Vein | 2000 |
Effects of three penetration enhancers on transcorneal permeation of cyclosporine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzalkonium Compounds; Biological Availability; Biological Transport; Cornea; Cyclosporine; Dimethyl Sulfoxide; Glycerol; Humans; Immunosuppressive Agents; Middle Aged; Permeability; Pharmaceutical Vehicles | 2001 |
Renal cholesterol accumulation: a durable response after acute and subacute renal insults.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cholesterol; Cholesterol Esters; Cyclosporine; Dehydration; Glomerulonephritis; Glycerol; Ischemia; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules; Male; Mice; Nephritis; Rats; Rats, Sprague-Dawley; Reperfusion; Tacrolimus | 2001 |
Comparative permeability of human and rabbit corneas to cyclosporin and tritiated water.
Topics: Animals; Benzalkonium Compounds; Cornea; Culture Techniques; Cyclosporine; Dimethyl Sulfoxide; Female; Frozen Sections; Glycerol; Humans; Immunosuppressive Agents; Male; Models, Biological; Permeability; Rabbits; Time Factors; Tritium; Water | 2002 |
Increased penetration of paclitaxel into the brain by inhibition of P-Glycoprotein.
Topics: Acridines; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Cyclosporine; Cyclosporins; Dose-Response Relationship, Drug; Female; Glycerol; Mice; Mice, Knockout; Paclitaxel; Tetrahydroisoquinolines; Time Factors | 2003 |
Ultrastructural evidence of early endothelial damage in coronary arteries of rat cardiac allografts.
Topics: Animals; Aorta; Coronary Vessels; Cyclosporine; Disease Models, Animal; Endothelium, Vascular; Glycerol; Heart Transplantation; Immunosuppressive Agents; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Pharmaceutical Vehicles; Rats; Rats, Inbred Lew; Silver Staining; Surface-Active Agents | 2003 |
Effect of melatonin on the malondialdehyde level of neutrophils in cyclosporine-treated rats.
Topics: Animals; Cyclosporine; Glycerol; Male; Malondialdehyde; Melatonin; Neutrophils; Rats; Rats, Sprague-Dawley | 2004 |
Cyclosporin neurotoxicity with Epstein-Barr virus-associated hemophagocytic syndrome.
Topics: Adult; Cyclosporine; Female; Glycerol; Herpesvirus 4, Human; Humans; Lymphohistiocytosis, Hemophagocytic; Magnetic Resonance Imaging; Neurotoxicity Syndromes | 2005 |
Cremophor EL releases cyclosporin A adsorbed on blood cells and blood vessels, and increases apparent plasma concentration of cyclosporin A.
Topics: Adsorption; Animals; Blood Cells; Blood Vessels; Cyclosporine; Glycerol; Male; Rats; Rats, Wistar | 2005 |
Slitlamp biomicroscopy of the tear film of patients using topical Restasis and Refresh Endura.
Topics: Administration, Topical; Cyclosporine; Diagnostic Techniques, Ophthalmological; Drug Therapy, Combination; Dry Eye Syndromes; Emulsions; Glycerol; Humans; Lipid Metabolism; Lipids; Micelles; Microscopy; Ophthalmic Solutions; Patient Compliance; Polysorbates; Tears | 2005 |
Micelles of methoxy poly(ethylene oxide)-b-poly(epsilon-caprolactone) as vehicles for the solubilization and controlled delivery of cyclosporine A.
Topics: Cyclosporine; Glycerol; Micelles; Pharmaceutical Vehicles; Polyesters; Solubility | 2005 |
Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols.
Topics: Aldehydes; Animals; Camellia sinensis; Chromatography, High Pressure Liquid; Cyclosporine; Flavonoids; Free Radicals; Glomerular Filtration Rate; Glycerol; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Olive Oil; Phenols; Phytotherapy; Plant Oils; Polyphenols; Rats; Rats, Sprague-Dawley; Tacrolimus | 2006 |
Biodegradable in situ gelling system for subcutaneous administration of ellagic acid and ellagic acid loaded nanoparticles: evaluation of their antioxidant potential against cyclosporine induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Biological Availability; Chitosan; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ellagic Acid; Ethanolamines; Gels; Glycerol; Immunosuppressive Agents; Kidney; Kinetics; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Propylene Glycol; Rats; Rats, Sprague-Dawley; Solvents; Temperature; Water | 2007 |
Excipients and their role in absorption: Influencing bioavailability of cyclosporine by triglycerides and polyglycerol esters.
Topics: Absorption; Animals; Biological Availability; Cyclosporine; Dogs; Drug Delivery Systems; Excipients; Glycerol; Immunosuppressive Agents; Male; Polymers; Rats; Rats, Wistar; Soybean Oil; Triglycerides | 2006 |
Transcriptional and physiological adaptation to defective protein-O-mannosylation in Candida albicans.
Topics: Adaptation, Physiological; Antifungal Agents; Candida albicans; Cyclosporine; Gene Expression Profiling; Gene Expression Regulation, Fungal; Glycerol; Glycolysis; Isoenzymes; Mannosyltransferases; Mutation; RNA, Fungal; RNA, Messenger | 2007 |
Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: in vitro and in vivo results.
Topics: Animals; Area Under Curve; Castor Oil; Cornea; Cyclosporine; Electrolytes; Emulsions; Excipients; Gels; Glycerol; Immunosuppressive Agents; Male; Ophthalmic Solutions; Polyethylene Glycols; Rabbits; Rheology; Stearic Acids; Surface-Active Agents; Viscosity; Water | 2009 |
Statistical optimization for improved production of cyclosporin a in solid-state fermentation.
Topics: Ammonium Sulfate; Coconut Oil; Culture Media; Cyclosporine; Dietary Fiber; Fermentation; Glycerol; Hypocreales; Industrial Microbiology; Iron Compounds; Leucine; Models, Biological; Models, Statistical; Plant Oils; Time Factors; Valine | 2009 |
Cyclosporine A-induced acute hepatotoxicity in guinea pigs is associated with endothelin-mediated decrease in local hepatic blood flow.
Topics: Animals; Bosentan; Cyclosporine; Dose-Response Relationship, Drug; Endothelins; Female; Glycerol; Guinea Pigs; Liver; Liver Circulation; Male; Peptides, Cyclic; Sulfonamides | 2011 |
Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calnexin; Cholestasis; Cryoprotective Agents; Cyclosporine; Dogs; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Silencing; Glycerol; Hep G2 Cells; HSC70 Heat-Shock Proteins; Humans; Mutation, Missense; Phenylbutyrates; Protein Transport; Thapsigargin | 2012 |
Cyclosporin nanosphere formulation for ophthalmic administration.
Topics: Administration, Ophthalmic; Animals; Anti-Inflammatory Agents; Cyclosporine; Eye; Glycerol; Hexoses; Lecithins; Nanospheres; Pharmaceutical Vehicles; Polysorbates; Propylene Glycol; Rabbits; Solvents; Surface-Active Agents; Triglycerides | 2012 |
The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue.
Topics: Adipocytes; Adiponectin; Adolescent; Adult; Aged; Carrier Proteins; Cell Survival; Cells, Cultured; Cyclosporine; Female; Gene Expression; Glycerol; Humans; Immunosuppressive Agents; Interleukin-6; Intra-Abdominal Fat; Lipid Metabolism; Lipolysis; Male; Middle Aged; Perilipin-1; Phosphoproteins; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Sterol Esterase; Subcutaneous Fat, Abdominal; Tacrolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Young Adult | 2013 |
Development and characterization of mucoadhesive chitosan films for ophthalmic delivery of cyclosporine A.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adhesiveness; Administration, Ophthalmic; beta-Cyclodextrins; Cell Line; Cell Survival; Chitosan; Cyclosporine; Drug Delivery Systems; Excipients; Glycerol; Humans; Interleukin-2; Mucous Membrane; Plasticizers; Water | 2014 |
Understanding drug distribution and release in ophthalmic emulsions through quantitative evaluation of formulation-associated variables.
Topics: Biological Transport; Cyclosporine; Diffusion; Drug Carriers; Drug Compounding; Drug Liberation; Emulsions; Eye; Fluprednisolone; Glycerol; Kinetics; Micelles; Models, Biological; Ocular Absorption; Ophthalmic Solutions; Phase Transition; Polysorbates; Surface Properties; Water | 2019 |