glycerol and cyclosporine

glycerol has been researched along with cyclosporine in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's25 (43.10)18.2507
2000's24 (41.38)29.6817
2010's9 (15.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ilhan, M; Tuncer, M; Yaris, E1
Chester, A; Mankad, P; O'Neil, G; Slavik, Z; Spatenka, J; Yacoub, M1
Brat, DJ; Brimijoin, S; Windebank, AJ1
Yee, GC1
Beliveau, R; Jetté, L; Leclerc, JM; Murphy, GF1
Chan, HS; Doyle, J; Greenberg, ML; Koren, G; Liau-Chu, M; Theis, JG1
Osann, K; Slater, L; Stupecky, M; Sweet, P; Wetzel, M1
Buckels, J; Cramb, R; Dousset, B; Krentz, AJ; Mayer, D; McMaster, P; Nattrass, M; Smith, JM1
Tuncer, M; Yaris, E1
Baker, RM; Brecher, ML; Chervinsky, DS; Hoelcle, MJ; Tebbi, CK1
Lodge, NJ1
Blexrud, MD; de Groen, PC; Windebank, AJ1
Cornblatt, B; Lee, EJ; Levy, C; Ross, DD; Schiffer, CA; Sridhara, R; Tong, Y; Wooten, PJ1
Alvestrand, A; Larsson, M; Tibell, A1
Ge, X; McCarthy, ET; Savin, VJ; Sharma, M; Sharma, R1
Baliga, R; Shah, SV; Ueda, N; Walker, PD2
Windebank, AJ1
Dahlback, M; Eirefelt, S; Karlsson, BW; Lundin, PD; Pierzynowski, SG; Podlesny, J; Siwinska-Golebiowska, H; Taljanski, W; Westrom, BR1
Brinkmann, T; Kleesiek, K; Körfer, R; Körner, M; Prohaska, W; Tiemann, C1
Koren, G; Liau-Chu, M; Theis, JG1
Michaud, LB1
Canada, AL; Ross, HJ; Slater, LM1
Hoshino, N; Minouchi, T; Ohmae, T; Shibata, N; Yamaji, A1
Heitman, J; Joseph, JD; Means, AR1
Escousse, A; Gouyon, JB; Guignard, JP; Justrabo, E; Prévot, A; Semama, DS1
Cloarec, A; Cornaire, G; Decourt, S; Houin, G; Legendre, JY; Saivin, S; Woodley, JF1
Huang, ZH; Murakami, T; Nagai, J; Okochi, A; Takano, M; Yumoto, R1
Bessard, G; Deveaux, G; Devillier, P; Hardy, G; Sessa, C; Stanke-Labesque, F1
Sparreboom, A; van Zuylen, L; Verweij, J1
Meyer, D; van der Bijl, P; van Eyk, AD1
Andoh, T; Bennett, WM; Zager, RA1
Barnes, AD; Buckels, JA; Dmitrewski, J; Krentz, AJ; Mayer, AD; Nattrass, M; Smith, J1
Bardelmeijer, HA; Beijnen, JH; Koopman, FJ; Malingré, MM; Ouwehand, M; Rosing, H; Schellens, JH; Schot, ME; Ten Bokkel Huinink, WW; Van Tellingen, O1
Engelbrecht, AH; Meyer, D; Van Der Bijl, P; Van Eyk, AD1
Beijnen, JH; Boogerd, W; Cleypool, C; Kemper, EM; Mos, HA; van Tellingen, O; van Zandbergen, AE1
Dyck, J; English, D; Kerjner, A; Lai, JC; Loo, S; McDonald, PC; McManus, BM; Moghadasian, MH; Tranfield, EM; Walker, DC; Wilson, JE; Wong, D1
Chang, EJ; Mun, KC1
Imashuku, S; Imoto, S; Koizumi, T; Mizuno, I; Murayama, T; Sada, A; Yakushijin, K1
Furukawa, H; Ishizaki, J; Jin, M; Miyamoto, K; Mizuhara, Y; Nomura, M; Shimada, T; Yokogawa, K1
Donnenfeld, ED; Greenman, HE; Perry, HD; Solomon, R1
Aliabadi, HM; Lavasanifar, A; Mahmud, A; Sharifabadi, AD1
Connor, HD; Forman, DT; Lemasters, JJ; Li, X; Mason, RP; Thurman, RG; Zhong, Z1
Italia, JL; Ravi Kumar, MN; Sharma, G; Sonaje, K; Tikoo, K1
Andrysek, T1
Cantero, PD; Ernst, JF; Lengsfeld, C; Pla, J; Prill, SK; Román, E; Subanović, M1
Chen, JS; Chen, PM; Chu, Z; Figg, WD; Gardner, ER; Liau, CT; Lin, YC; Sparreboom, A; Wang, HM; Yang, MH1
Gan, L; Gan, Y; Zhang, X; Zhu, C; Zhu, J1
Annapure, US; Singhal, RS; Survase, SA1
Atilla, P; Bolay, H; Cakar, AN; Dalkara, T; Emre-Aydıngöz, S; Erdem, SR; Tuncer, M1
Aït-Slimane, T; Delaunay, JL; Delautier, D; Durand-Schneider, AM; Gabillet, J; Gautherot, J; Housset, C; Maurice, M; Rada, A1
Aldouby, YH; Avramoff, A; Domb, AJ; Khan, W1
Dufour, S; Geny, B; Kindo, M; Lampert, E; Mettauer, B; N' Guessan, BB; Ribera, F; Sanchez, H; Ventura-Clapier, R; Zoll, J1
Aureliano, M; Carvalho, E; Eriksson, JW; Palming, J; Pereira, MJ; Rizell, M; Svensson, MK1
Ehinger, KH; Elmér, E; Hansson, MJ; Sjövall, F1
Adriaensens, P; Carleer, R; Hermans, K; Kerimova, S; Ludwig, A; Van den Plas, D; Weyenberg, W1
Ashraf, M; Choi, S; Cruz, CN; Dong, Y; Hengst, L; Hunt, R; Patel, D; Vo, A; Xu, X1

Reviews

5 review(s) available for glycerol and cyclosporine

ArticleYear
Dosage forms of cyclosporine.
    Pharmacotherapy, 1991, Volume: 11, Issue:6

    Topics: Administration, Oral; Capsules; Cyclosporine; Drug Stability; Glycerol; Humans; Injections, Intravenous; Solutions

1991
Oxidant mechanisms in toxic acute renal failure.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1997, Volume: 29, Issue:3

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Cyclosporine; Free Radicals; Gentamicins; Glycerol; Humans; Immunosuppressive Agents; Oxidants; Reactive Oxygen Species

1997
Methods for preventing reactions secondary to Cremophor EL.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:11

    Topics: Anaphylaxis; Chemistry, Pharmaceutical; Cyclosporine; Drug Compounding; Glycerol; Humans; Pharmaceutical Vehicles

1997
Oxidant mechanisms in toxic acute renal failure.
    Drug metabolism reviews, 1999, Volume: 31, Issue:4

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Cryoprotective Agents; Cyclosporine; Gentamicins; Glycerol; Hydrogen Peroxide; Immunosuppressive Agents; Oxidants; Rats; Reactive Oxygen Species

1999
Role of formulation vehicles in taxane pharmacology.
    Investigational new drugs, 2001, Volume: 19, Issue:2

    Topics: Animals; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chemistry, Pharmaceutical; Cyclosporine; Drug Hypersensitivity; Drug Resistance, Multiple; Glycerol; Humans; Micelles; Neoplasms; Nervous System Diseases; Paclitaxel; Polysorbates; Surface-Active Agents

2001

Trials

7 trial(s) available for glycerol and cyclosporine

ArticleYear
Anaphylactoid reactions in children receiving high-dose intravenous cyclosporine for reversal of tumor resistance: the causative role of improper dissolution of Cremophor EL.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:10

    Topics: Adolescent; Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Azo Compounds; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Ethanol; Glycerol; Humans; Immunosuppressive Agents; Infusions, Intravenous; Pharmaceutical Vehicles; Premedication; Rhabdomyosarcoma; Solubility; Solvents; Statistics, Nonparametric

1995
Metabolic effects of cyclosporin A and FK 506 in liver transplant recipients.
    Diabetes, 1993, Volume: 42, Issue:12

    Topics: Analysis of Variance; Azathioprine; Blood Glucose; Body Mass Index; C-Peptide; Cyclosporine; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Glycerol; Humans; Insulin; Ketone Bodies; Lactates; Liver Transplantation; Male; Middle Aged; Prospective Studies; Pyruvates; Pyruvic Acid; Reference Values; Tacrolimus

1993
Metabolic and hormonal effects of tacrolimus (FK506) or cyclosporin immunosuppression following renal transplantation.
    Diabetes, obesity & metabolism, 2001, Volume: 3, Issue:4

    Topics: Alanine; Blood Glucose; C-Peptide; Cyclosporine; Fatty Acids, Nonesterified; Follow-Up Studies; Glucose Tolerance Test; Glycerol; Humans; Immunosuppressive Agents; Insulin; Insulin Resistance; Insulin Secretion; Ketone Bodies; Kidney Transplantation; Lactates; Postprandial Period; Pyruvates; Reference Values; Tacrolimus; Time Factors

2001
The co-solvent Cremophor EL limits absorption of orally administered paclitaxel in cancer patients.
    British journal of cancer, 2001, Nov-16, Volume: 85, Issue:10

    Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Area Under Curve; Cyclosporine; Drug Combinations; Feces; Glycerol; Humans; Intestinal Absorption; Neoplasms; Paclitaxel; Pharmaceutical Vehicles; Polysorbates; Solvents

2001
Oral bioavailability of a novel paclitaxel formulation (Genetaxyl) administered with cyclosporin A in cancer patients.
    Anti-cancer drugs, 2008, Volume: 19, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Availability; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycerol; Humans; Immunosuppressive Agents; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Paclitaxel

2008
Oxidative capacities of cardiac and skeletal muscles of heart transplant recipients: mitochondrial effects of cyclosporin-A and its vehicle Cremophor-EL.
    Fundamental & clinical pharmacology, 2014, Volume: 28, Issue:2

    Topics: Cyclosporine; Dose-Response Relationship, Drug; Electron Transport; Electron Transport Chain Complex Proteins; Female; Glycerol; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Mitochondria, Heart; Mitochondria, Muscle; Muscle, Skeletal; Myocardium; Oxygen Consumption; Pharmaceutical Vehicles; Transplants

2014
Bioequivalence and tolerability assessment of a novel intravenous ciclosporin lipid emulsion compared to branded ciclosporin in Cremophor ® EL.
    Clinical drug investigation, 2013, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Cyclosporine; Emulsifying Agents; Excipients; Fat Emulsions, Intravenous; Female; Glycerol; Half-Life; Humans; Immunosuppressive Agents; Infusions, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; South Africa; Therapeutic Equivalency; Young Adult

2013

Other Studies

46 other study(ies) available for glycerol and cyclosporine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Actions of cyclosporin A preparation and Cremophor-EL in rabbit mesenteric artery and thoracic aorta in vitro.
    Clinical science (London, England : 1979), 1992, Volume: 83, Issue:2

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclosporine; Drug Synergism; Glycerol; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Rabbits; Solvents; Vasoconstriction; Vasodilation

1992
Acute effects of cyclosporin and cremophor EL on endothelial function and vascular smooth muscle in the isolated rat heart.
    Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:1

    Topics: Animals; Coronary Circulation; Cyclosporine; Endothelium, Vascular; Glycerol; Heart; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Perfusion; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains

1992
Emulsifier for intravenous cyclosporin inhibits neurite outgrowth, causes deficits in rapid axonal transport and leads to structural abnormalities in differentiating N1E.115 neuroblastoma.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: Animals; Cell Differentiation; Cyclosporine; Glycerol; Mice; Neurites; Neuroblastoma; Pharmaceutical Vehicles; Tumor Cells, Cultured; Video Recording

1992
Interaction of drugs with P-glycoprotein in brain capillaries.
    Biochemical pharmacology, 1995, Nov-09, Volume: 50, Issue:10

    Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blood-Brain Barrier; Brain; Capillaries; Cyclosporine; Cyclosporins; Drug Interactions; Glycerol; In Vitro Techniques; Iodine Radioisotopes; Male; Prazosin; Rats; Rats, Sprague-Dawley; Time Factors; Tritium

1995
Comparison of cyclosporin A, verapamil, PSC-833 and cremophor EL as enhancing agents of VP-16 in murine lymphoid leukemias.
    Leukemia research, 1995, Volume: 19, Issue:8

    Topics: Animals; Cell Survival; Cyclosporine; Cyclosporins; Drug Synergism; Etoposide; Glycerol; Leukemia L1210; Leukemia P388; Mice; Survival Analysis; Tumor Cells, Cultured; Verapamil

1995
The effect of indomethacin on cyclosporin A- and its solvent-induced inhibition of endothelium-dependent relaxation and the drug-induced contraction of rabbit isolated arteries.
    General pharmacology, 1995, Volume: 26, Issue:1

    Topics: Acetylcholine; Animals; Cyclosporine; Endothelium, Vascular; Glycerol; In Vitro Techniques; Indomethacin; Male; Pharmaceutical Vehicles; Rabbits; Vasoconstriction; Vasodilation

1995
Reversal of C1300 murine neuroblastoma multidrug resistance by cremophorEL, a solvent for cyclosporin A.
    Cancer biotherapy, 1993,Spring, Volume: 8, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Chromatography, High Pressure Liquid; Clone Cells; Cyclosporine; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Glycerol; Harringtonines; Homoharringtonine; Intracellular Fluid; Mice; Neuroblastoma; Pharmaceutical Vehicles; Solvents; Tumor Cells, Cultured

1993
Direct vasoconstrictor effects of sandimmune (cyclosporine A) are mediated by its vehicle cremophor EL: inhibition by the thromboxane A2/prostaglandin endoperoxide receptor antagonist ifetroban.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclosporine; Dose-Response Relationship, Drug; Glyburide; Glycerol; In Vitro Techniques; Male; Oxazoles; Pharmaceutical Vehicles; Propionates; Rabbits; Receptors, Thromboxane; Ricinoleic Acids; Vasoconstrictor Agents

1994
Potential neurotoxicity of the solvent vehicle for cyclosporine.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:2

    Topics: Animals; Cyclosporine; Demyelinating Diseases; Ethanol; Female; Ganglia, Spinal; Glycerol; Humans; Nervous System; Pharmaceutical Vehicles; Pregnancy; Rats; Rats, Sprague-Dawley

1994
Synergistic reversal of multidrug-resistance phenotype in acute myeloid leukemia cells by cyclosporin A and cremophor EL.
    Blood, 1994, Mar-01, Volume: 83, Issue:5

    Topics: Cell Survival; Cyclosporine; Daunorubicin; Drug Resistance; Drug Synergism; Female; Glycerol; Humans; Leukemia, Myeloid, Acute; Male; Tumor Cells, Cultured

1994
Dissolving intravenous cyclosporin A in a fat emulsion carrier prevents acute renal side effects in the rat.
    Transplant international : official journal of the European Society for Organ Transplantation, 1993, Volume: 6, Issue:2

    Topics: Animals; Cyclosporine; Drug Carriers; Emulsions; Glomerular Filtration Rate; Glycerol; Infusions, Intravenous; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; Solubility; Soybean Oil

1993
Cyclosporine protects glomeruli from FSGS factor via an increase in glomerular cAMP.
    Transplantation, 1996, Dec-27, Volume: 62, Issue:12

    Topics: Albumins; Animals; Cyclic AMP; Cyclosporine; Glomerulosclerosis, Focal Segmental; Glycerol; Humans; Kidney Glomerulus; Male; Microscopy, Electron; Permeability; Rats; Rats, Sprague-Dawley; Sodium Chloride

1996
The vehicle for cyclosporine is neurotoxic in vitro.
    Annals of neurology, 1997, Volume: 41, Issue:4

    Topics: Animals; Axons; Cells, Cultured; Cyclosporine; Demyelinating Diseases; Glycerol; Humans; Neurons; Oligodendroglia; Pharmaceutical Vehicles

1997
Pulmonary delivery of intratracheally instilled and aerosolized cyclosporine A to young and adult rats.
    Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:8

    Topics: Aerosols; Aging; Animals; Biological Availability; Cyclosporine; Female; Glycerol; Half-Life; Lung; Male; Rats; Rats, Sprague-Dawley; Trachea

1997
Effect of cyclosporine A on the release of tissue factor pathway inhibitor from endothelial cells in heart transplant patients and cell culture.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1997, Volume: 35, Issue:9

    Topics: Adolescent; Adult; Calcimycin; Calcium; Cell Division; Cells, Cultured; Cyclosporine; Endothelium, Vascular; Female; Glycerol; Heart Transplantation; Humans; Ionophores; Lipoproteins; Male; Middle Aged; Pharmaceutical Vehicles; von Willebrand Factor

1997
Mechanism of anaphylactoid reactions: improper preparation of high-dose intravenous cyclosporine leads to bolus infusion of Cremophor EL and cyclosporine.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:11

    Topics: Anaphylaxis; Chemistry, Pharmaceutical; Cyclosporine; Drug Compounding; Ethanol; Glycerol; Humans; Pharmaceutical Vehicles; Solutions

1997
Cyclosporin A enhances paclitaxel toxicity against leukemia and respiratory epithelial cancers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclosporine; Cytokines; Disease Models, Animal; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Glycerol; Growth Substances; Humans; Immunosuppressive Agents; Leukemia; Mice; Paclitaxel; Respiratory Tract Neoplasms; Survival Rate; Treatment Outcome; Tumor Cells, Cultured

1997
Influence of glycerol-induced acute renal failure on the pharmacokinetics of cyclosporin in rats.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:4

    Topics: Acetaminophen; Acute Kidney Injury; Administration, Oral; Analgesics, Non-Narcotic; Animals; Area Under Curve; Blood Urea Nitrogen; Creatine; Cyclosporine; Gastric Emptying; Glycerol; Ileum; Immunosuppressive Agents; In Vitro Techniques; Injections, Intravenous; Jejunum; Liver; Male; Rats; Rats, Sprague-Dawley; Time Factors

1999
Molecular cloning and characterization of Aspergillus nidulans cyclophilin B.
    Fungal genetics and biology : FG & B, 1999, Volume: 27, Issue:1

    Topics: Amino Acid Sequence; Animals; Antifungal Agents; Aspergillus nidulans; Base Sequence; Calcineurin; Cattle; Cloning, Molecular; Culture Media; Cyclophilins; Cyclosporine; DNA, Fungal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Glycerol; Hot Temperature; Immunophilins; Microbial Sensitivity Tests; Molecular Sequence Data; Peptidylprolyl Isomerase; Recombinant Fusion Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Threonine

1999
Acute cyclosporine A-induced nephrotoxicity: a rabbit model.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:5

    Topics: Acute Disease; Animals; Cyclosporine; Glycerol; Kidney; Kidney Diseases; Male; Rabbits; Renal Circulation; Surface-Active Agents

2000
Effect of polyoxyl 35 castor oil and Polysorbate 80 on the intestinal absorption of digoxin in vitro.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:6

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiotonic Agents; Cyclosporine; Digoxin; Glycerol; In Vitro Techniques; Intestinal Absorption; Intestine, Small; L-Lactate Dehydrogenase; Micelles; Polysorbates; Rats; Surface-Active Agents

2000
Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure.
    European journal of pharmacology, 2000, Oct-20, Volume: 406, Issue:3

    Topics: Acute Kidney Injury; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Brain Chemistry; Caco-2 Cells; Cyclosporine; Glycerol; Humans; Kidney; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Wistar; Rhodamine 123

2000
Cyclosporine A and cremophor EL induce contractions of human saphenous vein: involvement of thromboxane A2 receptor-dependent pathway.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:6

    Topics: Biphenyl Compounds; Cyclosporine; Fibrinolytic Agents; Glycerol; Heptanoic Acids; Humans; Immunosuppressive Agents; In Vitro Techniques; Lipoxygenase Inhibitors; Muscle Contraction; Muscle, Smooth, Vascular; Pharmaceutical Vehicles; Receptors, Thromboxane; Saphenous Vein

2000
Effects of three penetration enhancers on transcorneal permeation of cyclosporine.
    Cornea, 2001, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzalkonium Compounds; Biological Availability; Biological Transport; Cornea; Cyclosporine; Dimethyl Sulfoxide; Glycerol; Humans; Immunosuppressive Agents; Middle Aged; Permeability; Pharmaceutical Vehicles

2001
Renal cholesterol accumulation: a durable response after acute and subacute renal insults.
    The American journal of pathology, 2001, Volume: 159, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cholesterol; Cholesterol Esters; Cyclosporine; Dehydration; Glomerulonephritis; Glycerol; Ischemia; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules; Male; Mice; Nephritis; Rats; Rats, Sprague-Dawley; Reperfusion; Tacrolimus

2001
Comparative permeability of human and rabbit corneas to cyclosporin and tritiated water.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2002, Volume: 18, Issue:5

    Topics: Animals; Benzalkonium Compounds; Cornea; Culture Techniques; Cyclosporine; Dimethyl Sulfoxide; Female; Frozen Sections; Glycerol; Humans; Immunosuppressive Agents; Male; Models, Biological; Permeability; Rabbits; Time Factors; Tritium; Water

2002
Increased penetration of paclitaxel into the brain by inhibition of P-Glycoprotein.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:7

    Topics: Acridines; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Cyclosporine; Cyclosporins; Dose-Response Relationship, Drug; Female; Glycerol; Mice; Mice, Knockout; Paclitaxel; Tetrahydroisoquinolines; Time Factors

2003
Ultrastructural evidence of early endothelial damage in coronary arteries of rat cardiac allografts.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2003, Volume: 22, Issue:9

    Topics: Animals; Aorta; Coronary Vessels; Cyclosporine; Disease Models, Animal; Endothelium, Vascular; Glycerol; Heart Transplantation; Immunosuppressive Agents; Male; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Pharmaceutical Vehicles; Rats; Rats, Inbred Lew; Silver Staining; Surface-Active Agents

2003
Effect of melatonin on the malondialdehyde level of neutrophils in cyclosporine-treated rats.
    Transplantation proceedings, 2004, Volume: 36, Issue:7

    Topics: Animals; Cyclosporine; Glycerol; Male; Malondialdehyde; Melatonin; Neutrophils; Rats; Rats, Sprague-Dawley

2004
Cyclosporin neurotoxicity with Epstein-Barr virus-associated hemophagocytic syndrome.
    Haematologica, 2005, Volume: 90, Issue:3

    Topics: Adult; Cyclosporine; Female; Glycerol; Herpesvirus 4, Human; Humans; Lymphohistiocytosis, Hemophagocytic; Magnetic Resonance Imaging; Neurotoxicity Syndromes

2005
Cremophor EL releases cyclosporin A adsorbed on blood cells and blood vessels, and increases apparent plasma concentration of cyclosporin A.
    International journal of pharmaceutics, 2005, Apr-11, Volume: 293, Issue:1-2

    Topics: Adsorption; Animals; Blood Cells; Blood Vessels; Cyclosporine; Glycerol; Male; Rats; Rats, Wistar

2005
Slitlamp biomicroscopy of the tear film of patients using topical Restasis and Refresh Endura.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:4

    Topics: Administration, Topical; Cyclosporine; Diagnostic Techniques, Ophthalmological; Drug Therapy, Combination; Dry Eye Syndromes; Emulsions; Glycerol; Humans; Lipid Metabolism; Lipids; Micelles; Microscopy; Ophthalmic Solutions; Patient Compliance; Polysorbates; Tears

2005
Micelles of methoxy poly(ethylene oxide)-b-poly(epsilon-caprolactone) as vehicles for the solubilization and controlled delivery of cyclosporine A.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, May-18, Volume: 104, Issue:2

    Topics: Cyclosporine; Glycerol; Micelles; Pharmaceutical Vehicles; Polyesters; Solubility

2005
Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:11

    Topics: Aldehydes; Animals; Camellia sinensis; Chromatography, High Pressure Liquid; Cyclosporine; Flavonoids; Free Radicals; Glomerular Filtration Rate; Glycerol; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Olive Oil; Phenols; Phytotherapy; Plant Oils; Polyphenols; Rats; Rats, Sprague-Dawley; Tacrolimus

2006
Biodegradable in situ gelling system for subcutaneous administration of ellagic acid and ellagic acid loaded nanoparticles: evaluation of their antioxidant potential against cyclosporine induced nephrotoxicity in rats.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Mar-12, Volume: 118, Issue:1

    Topics: Animals; Antioxidants; Biological Availability; Chitosan; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ellagic Acid; Ethanolamines; Gels; Glycerol; Immunosuppressive Agents; Kidney; Kinetics; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Propylene Glycol; Rats; Rats, Sprague-Dawley; Solvents; Temperature; Water

2007
Excipients and their role in absorption: Influencing bioavailability of cyclosporine by triglycerides and polyglycerol esters.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2006, Volume: 150, Issue:2

    Topics: Absorption; Animals; Biological Availability; Cyclosporine; Dogs; Drug Delivery Systems; Excipients; Glycerol; Immunosuppressive Agents; Male; Polymers; Rats; Rats, Wistar; Soybean Oil; Triglycerides

2006
Transcriptional and physiological adaptation to defective protein-O-mannosylation in Candida albicans.
    Molecular microbiology, 2007, Volume: 64, Issue:4

    Topics: Adaptation, Physiological; Antifungal Agents; Candida albicans; Cyclosporine; Gene Expression Profiling; Gene Expression Regulation, Fungal; Glycerol; Glycolysis; Isoenzymes; Mannosyltransferases; Mutation; RNA, Fungal; RNA, Messenger

2007
Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: in vitro and in vivo results.
    International journal of pharmaceutics, 2009, Jan-05, Volume: 365, Issue:1-2

    Topics: Animals; Area Under Curve; Castor Oil; Cornea; Cyclosporine; Electrolytes; Emulsions; Excipients; Gels; Glycerol; Immunosuppressive Agents; Male; Ophthalmic Solutions; Polyethylene Glycols; Rabbits; Rheology; Stearic Acids; Surface-Active Agents; Viscosity; Water

2009
Statistical optimization for improved production of cyclosporin a in solid-state fermentation.
    Journal of microbiology and biotechnology, 2009, Volume: 19, Issue:11

    Topics: Ammonium Sulfate; Coconut Oil; Culture Media; Cyclosporine; Dietary Fiber; Fermentation; Glycerol; Hypocreales; Industrial Microbiology; Iron Compounds; Leucine; Models, Biological; Models, Statistical; Plant Oils; Time Factors; Valine

2009
Cyclosporine A-induced acute hepatotoxicity in guinea pigs is associated with endothelin-mediated decrease in local hepatic blood flow.
    Life sciences, 2011, Apr-25, Volume: 88, Issue:17-18

    Topics: Animals; Bosentan; Cyclosporine; Dose-Response Relationship, Drug; Endothelins; Female; Glycerol; Guinea Pigs; Liver; Liver Circulation; Male; Peptides, Cyclic; Sulfonamides

2011
Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.
    The Journal of biological chemistry, 2012, Feb-10, Volume: 287, Issue:7

    Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calnexin; Cholestasis; Cryoprotective Agents; Cyclosporine; Dogs; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Silencing; Glycerol; Hep G2 Cells; HSC70 Heat-Shock Proteins; Humans; Mutation, Missense; Phenylbutyrates; Protein Transport; Thapsigargin

2012
Cyclosporin nanosphere formulation for ophthalmic administration.
    International journal of pharmaceutics, 2012, Nov-01, Volume: 437, Issue:1-2

    Topics: Administration, Ophthalmic; Animals; Anti-Inflammatory Agents; Cyclosporine; Eye; Glycerol; Hexoses; Lecithins; Nanospheres; Pharmaceutical Vehicles; Polysorbates; Propylene Glycol; Rabbits; Solvents; Surface-Active Agents; Triglycerides

2012
The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue.
    Molecular and cellular endocrinology, 2013, Jan-30, Volume: 365, Issue:2

    Topics: Adipocytes; Adiponectin; Adolescent; Adult; Aged; Carrier Proteins; Cell Survival; Cells, Cultured; Cyclosporine; Female; Gene Expression; Glycerol; Humans; Immunosuppressive Agents; Interleukin-6; Intra-Abdominal Fat; Lipid Metabolism; Lipolysis; Male; Middle Aged; Perilipin-1; Phosphoproteins; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Sterol Esterase; Subcutaneous Fat, Abdominal; Tacrolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Young Adult

2013
Development and characterization of mucoadhesive chitosan films for ophthalmic delivery of cyclosporine A.
    International journal of pharmaceutics, 2014, Sep-10, Volume: 472, Issue:1-2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adhesiveness; Administration, Ophthalmic; beta-Cyclodextrins; Cell Line; Cell Survival; Chitosan; Cyclosporine; Drug Delivery Systems; Excipients; Glycerol; Humans; Interleukin-2; Mucous Membrane; Plasticizers; Water

2014
Understanding drug distribution and release in ophthalmic emulsions through quantitative evaluation of formulation-associated variables.
    Journal of controlled release : official journal of the Controlled Release Society, 2019, 11-10, Volume: 313

    Topics: Biological Transport; Cyclosporine; Diffusion; Drug Carriers; Drug Compounding; Drug Liberation; Emulsions; Eye; Fluprednisolone; Glycerol; Kinetics; Micelles; Models, Biological; Ocular Absorption; Ophthalmic Solutions; Phase Transition; Polysorbates; Surface Properties; Water

2019