glyburide and nicardipine

glyburide has been researched along with nicardipine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (22.22)18.2507
2000's11 (40.74)29.6817
2010's8 (29.63)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Norman, BH1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Calixto, JB; Guimarães, CL; Rae, GA1
Ito, S; Itoh, T; Shafiq, J; Suzuki, H1
Aupetit-Faisant, B; Cailmail, S; Kirstetter, P; Komeichi, H; Lebrec, D; Moreau, R; Yang, S1
Motohashi, O; Sugai, K; Suzuki, M; Yanagisawa, T; Yoshimoto, T1
Beech, DJ; Prior, HM; Yates, MS1
Kajiwara, H; Kameda, H; Takasaki, A; Takeo, S; Tanonaka, K1
Bartlett, IS; Marshall, JM1
Hong, SJ; Liang, HC; Shen, CJ1
Du, JB; Du, SX; Jin, HF; Tang, CS; Zhang, CY1
Koren, G; Lubetsky, A; Pollex, E1
Ben-Zvi, Z; Erez, O; Eshkoli, T; Feinshtein, V; Holcberg, G; Sheiner, E; Sheizaf, B1

Reviews

3 review(s) available for glyburide and nicardipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies.
    Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20

    Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Evaluation, Preclinical; Hepatocytes; Humans; Liver; Mitochondria, Liver; Pharmaceutical Preparations; Risk Assessment; Tissue Distribution

2020
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022

Other Studies

24 other study(ies) available for glyburide and nicardipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Potent constrictor actions of endothelin-1, endothelin-2, and endothelin-3 in rat isolated portal vein.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl

    Topics: Alkaloids; Animals; Benzopyrans; Calcium; Cromakalim; Endothelins; Glyburide; Indomethacin; Male; Mesenteric Veins; Nicardipine; Phorbols; Portal Vein; Protein Kinase C; Pyrroles; Rats; Rats, Inbred Strains; Staurosporine; Vasoconstriction; Vasodilator Agents

1992
Effects of a newly synthesized K+ channel opener, Y-26763, on noradrenaline-induced Ca2+ mobilization in smooth muscle of the rabbit mesenteric artery.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Calcium; Dose-Response Relationship, Drug; Electrophysiology; Escin; Glyburide; In Vitro Techniques; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Potassium Channels; Rabbits

1994
Effects of glibenclamide on systemic and splanchnic haemodynamics in conscious rats.
    British journal of pharmacology, 1994, Volume: 112, Issue:2

    Topics: Animals; Corticosterone; Diazoxide; Glyburide; Hemodynamics; Injections, Intraventricular; Male; Nicardipine; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasoconstriction

1994
Levcromakalim decreases vascular tone, cytoplasmic Ca2+ and Ca2+ sensitivity in canine basilar artery.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:4

    Topics: Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Cromakalim; Cytoplasm; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Peptides; Potassium Channel Blockers; Potassium Channels; Serotonin; Tetraethylammonium; Vasoconstriction

1998
Role of K+ channels in A2A adenosine receptor-mediated dilation of the pressurized renal arcuate artery.
    British journal of pharmacology, 1999, Volume: 126, Issue:2

    Topics: 4-Aminopyridine; Adenosine; Amifampridine; Animals; Antihypertensive Agents; Apamin; Arteries; Barium; Cromakalim; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Kidney; Male; Nicardipine; Ouabain; Peptides; Phenethylamines; Potassium; Potassium Channels; Pressure; Purinergic P1 Receptor Agonists; Rabbits; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilation; Vasodilator Agents

1999
Relationship between myocardial cation content and injury in reperfused rat hearts treated with cation channel blockers.
    European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cations; Creatine Kinase; Diltiazem; Dose-Response Relationship, Drug; Glyburide; Heart Ventricles; Hypoglycemic Agents; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Nicardipine; Procainamide; Rats; Rats, Wistar; Tetrodotoxin

1999
Analysis of the effects of graded levels of hypoxia on noradrenaline-evoked contraction in the rat iliac artery in vitro.
    Experimental physiology, 2002, Volume: 87, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Endothelium, Vascular; Glyburide; Hypoglycemic Agents; Hypoxia; Iliac Artery; In Vitro Techniques; Male; Nicardipine; Norepinephrine; Oxygen; Potassium; Potassium Channel Blockers; Quinoxalines; Rats; Rats, Wistar; Tetraethylammonium; Vasoconstrictor Agents

2002
Alteration of cyclopiazonic acid-mediated contracture of mouse diaphragm after denervation.
    Pharmacology, 2005, Volume: 73, Issue:4

    Topics: Action Potentials; Animals; Biological Assay; Boron Compounds; Caffeine; Cromakalim; Crotalid Venoms; Diaphragm; Electric Stimulation; Estrenes; Female; Glyburide; Indoles; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle Denervation; Nicardipine; Phrenic Nerve; Pyrrolidinones; Sarcoplasmic Reticulum

2005
[Vasorelaxant effect of sulfur dioxide derivatives on isolated aortic rings of rats and its mechanisms].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2006, Dec-18, Volume: 38, Issue:6

    Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; KATP Channels; Male; Nicardipine; Norepinephrine; Potassium Channel Blockers; Rats; Rats, Wistar; Sulfites; Sulfur Dioxide; Vasodilation; Vasodilator Agents

2006
The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta.
    Placenta, 2008, Volume: 29, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Survival; Female; Glyburide; Humans; Hypoglycemic Agents; Neoplasm Proteins; Nicardipine; Organ Culture Techniques; Oxygen Consumption; Placenta; Pregnancy

2008
Cannabidiol enhances xenobiotic permeability through the human placental barrier by direct inhibition of breast cancer resistance protein: an ex vivo study.
    American journal of obstetrics and gynecology, 2013, Volume: 209, Issue:6

    Topics: Analysis of Variance; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cannabidiol; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Glyburide; Humans; Maternal-Fetal Exchange; Mitoxantrone; Models, Biological; Neoplasm Proteins; Nicardipine; Perfusion; Placenta; Pregnancy; Trophoblasts

2013