glyburide and mibefradil

glyburide has been researched along with mibefradil in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Lombardo, F; Obach, RS; Waters, NJ1
Caron, G; Ermondi, G; Visentin, S1
Campillo, NE; Guerra, A; Páez, JA1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cho, YS; Hwang, EM; Jung, SY; Lim, SM; Min, SJ; Pae, AN; Park, KD; Viswanath, AN1
Backenköhler, U; Dörge, H; Heusch, G; Jalowy, A; Post, H; Schulz, R; Vahlhaus, C1
Baxter, GF; Gadgil, S; Mocanu, MM; Yellon, DM1
Kito, Y; Sanders, KM; Ward, SM1
Mandi, G; Mishra, SK; Raviprakash, V; Sarkar, SN1

Other Studies

11 other study(ies) available for glyburide and mibefradil

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.
    Chemical biology & drug design, 2016, Volume: 88, Issue:6

    Topics: Animals; Computer Simulation; Crystallography, X-Ray; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Mice; Mice, Knockout; Molecular Docking Simulation; Potassium Channels, Tandem Pore Domain

2016
Unique cardioprotective action of the new calcium antagonist mibefradil.
    Circulation, 1999, Jan-19, Volume: 99, Issue:2

    Topics: Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Glyburide; Heart; Heart Rate; Heart Ventricles; Mibefradil; Myocardial Infarction; Pressure; Swine; Tetrahydronaphthalenes; Verapamil

1999
Mibefradil, a T-type and L-type calcium channel blocker, limits infarct size through a glibenclamide-sensitive mechanism.
    Cardiovascular drugs and therapy, 1999, Volume: 13, Issue:2

    Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Disease Progression; Enzyme Activation; Glyburide; Hemodynamics; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Mibefradil; Myocardial Infarction; Protein Kinase C; Rats; Rats, Sprague-Dawley; Risk Factors; Tetrahydronaphthalenes

1999
Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine.
    American journal of physiology. Cell physiology, 2005, Volume: 288, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Biological Clocks; Caffeine; Calcium Channel Blockers; Central Nervous System Stimulants; Electrophysiology; Glyburide; In Vitro Techniques; Intestine, Small; Membrane Potentials; Mibefradil; Mice; Mice, Inbred BALB C; Myocytes, Smooth Muscle; Nifedipine; Pinacidil; Vasodilator Agents

2005
Effects of calcium channel blocker, mibefradil, and potassium channel opener, pinacidil, on the contractile response of mid-pregnant goat myometrium.
    Indian journal of experimental biology, 2005, Volume: 43, Issue:9

    Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Glyburide; Goats; Humans; Mibefradil; Myometrium; Oxytocin; Pinacidil; Potassium; Potassium Channels; Pregnancy; Pregnancy, Animal; Uterine Contraction; Uterus

2005