glyburide has been researched along with metformin in 453 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (6.84) | 18.7374 |
| 1990's | 58 (12.80) | 18.2507 |
| 2000's | 156 (34.44) | 29.6817 |
| 2010's | 166 (36.64) | 24.3611 |
| 2020's | 42 (9.27) | 2.80 |
| Authors | Studies |
|---|---|
| Alessi, TR; Bagli, JF; Browne, EN; Bullington, J; Ellingboe, JW; Guinosso, CJ; Guzzo, F; Lombardo, LJ; Nguyen, TT; Wrenn, J | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Ahmad, P; Kumar, A; Pathak, SR; Ray, S; Srivastava, AK; Tewari, P | 1 |
| Pratap, R; Shukla, P; Singh, AB; Srivastava, AK | 1 |
| Dwivedi, AP; Kumar, S; Sahu, DP; Singh, AB; Srivastava, AK; Varshney, V | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahmad, P; Kumar, A; Maurya, RA; Singh, AB; Srivastava, AK | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Ahmad, P; Kumar, A; Maurya, RA; Sharma, S; Singh, AB; Srivastava, AK; Tamrakar, AK | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Bhatia, G; Kumar, A; Maurya, RA; Sharma, S; Srivastava, AK; Srivastava, SP; Tamrakar, AK; Tripathi, VD | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Hsieh, PH; Lam, SH; Lee, SS; Ruan, CT; Su, MJ | 1 |
| Ahmad, P; Gupta, LP; Kumar, A; Rahuja, N; Sharma, S; Srivastava, AK; Srivastava, SP; Tamrakar, AK | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Darvesh, AS; Geldenhuys, WJ; Leeper, TC; Morris, DL; Sullivan, PG; Yonutas, HM | 1 |
| Chen, M; Jiang, H; Jin, Z; Ma, Y; Sun, H; Wang, K; Yu, P; Zhang, M; Zhang, Y; Zheng, H | 1 |
| Coetzee, EJ; Jackson, WP | 2 |
| Bloom, A; Bulpitt, CJ; Shaw, KM | 1 |
| Alberti, KG; Hinks, L; Lloyd, B; Nattrass, M; Todd, PG | 1 |
| Di Saverio, S; Roncaia, R; Torri, A; Zanni, A | 1 |
| Bennett, MA; Fitzgerald, MG; Malins, JM; Pentecost, BL; Soler, NG | 1 |
| Andrews, WJ; Boreham, C; Boyd, K; Hadden, DR; Rogers, C | 1 |
| Madhavan, R; Sankaran, JR; Seshasaianam, C; Seshiah, V; Shanker, R; Sundaram, A; Venkataraman, S | 1 |
| Caffau, C; Cernigoi, AM; Velussi, M; Viezzoli, L | 1 |
| Buscema, M; Italia, S; Mazzarino, S; Rabuazzo, AM; Sangiorgio, L; Squatrito, S; Trischitta, V; Vigneri, R | 1 |
| Birkeland, KI; Chatzipanagiotou, F; Hanssen, KF; Vaaler, S | 1 |
| Bravi, MC; De Mattia, G; Faldetta, MC; Laurenti, O | 1 |
| Cooper, GJ; Moore, CX | 1 |
| Bianchi, U; Cacciapuoti, F; D'Avino, M; Lama, D; Spiezia, R; Varricchio, M | 1 |
| Booth, NA; Grant, PJ; Prentice, CR; Stickland, MH | 1 |
| Hermann, LS; Karlsson, JE; Sjöstrand, A | 1 |
| Hermann, LS; Kjellström, T; Nilsson-Ehle, P | 1 |
| Elkeles, RS | 1 |
| Bitzén, PO; Hermann, LS; Kjellström, T; Lindgärde, F; Scherstén, B | 1 |
| Italia, S; Mazzarino, S; Rabuazzo, MA; Squatrito, S; Trischitta, V; Vigneri, R | 1 |
| Huupponen, R; Karvonen, I; Rytömaa, K; Sotaniemi, EA; Vierimaa, E; Vuoti, MJ | 1 |
| Abu-Jayyab, AR; al-Bekairi, AM; el-Denshary, ES; el-Sawaf, HA | 1 |
| Mehnert, H | 1 |
| Abu-Jayyab, AR; al-Ahmed, FA; el-Denshary, ES; el-Sawaf, HA; Zaki, M | 1 |
| Ekstrand, A; Eriksson, J; Franssila-Kallunki, A; Groop, L; Saloranta, C; Schalin, C; Widén, E | 1 |
| Janka, HU | 1 |
| Elkeles, RS; Rains, SG; Richmond, W; Wilson, GA | 1 |
| Augustin-Pascalis, I; Mirouze, J; Orsetti, A; Richard, JL; Rodier, M | 1 |
| Hawkins, M; Heptinstall, S; Peacock, I | 1 |
| Peacock, I; Selby, C; Tattersall, RB; Watts, R | 1 |
| Finlay, GJ; Holdaway, IM; Mountjoy, KG | 1 |
| Campbell, IW | 2 |
| Tattersall, RB | 1 |
| Beringer, A | 1 |
| Edlén, A | 1 |
| Bloom, A | 1 |
| Katsilambros, N; Nierle, C; Pfeiffer, EE; Schatz, H | 1 |
| Bhatia, SK; Hadden, DR; Montgomery, DA | 1 |
| Chiasson, JL; Hamet, P | 1 |
| Kimura, M; Suzuki, J | 1 |
| Peacock, I; Tattersall, RB | 1 |
| Bailey, CJ; Billingham, MS; Hall, RA; Simpson, S | 2 |
| Lunetta, M; Mughini, L; Mughini, MT; Presti, C | 1 |
| Bailey, CJ; Broadbent, ME | 1 |
| Chow, CC; Cockram, CS; Sorensen, JP; Tsang, LW | 1 |
| DeFronzo, RA; Goodman, AM | 1 |
| Bitzén, PO; Hermann, LS; Kjellström, T; Lindgärde, F; Melander, A; Scherstén, B | 1 |
| Hermann, LS; Melander, A; Scherstén, B | 1 |
| Chan, JC; Cockram, CS; Critchley, JA; Tomlinson, B; Walden, RJ | 1 |
| Lamey, PJ; Lewis, MA; Nolan, A; Paterson, AJ; Rademaker, M | 1 |
| Bjelajac, A; Carson, DS; Goo, AK | 1 |
| Clauson, P; Efendic, S; Karlander, S; Steen, L | 1 |
| A-Rahim, YI; Beyer, KH; Vesell, ES | 1 |
| Halvatsiotis, PG; Raptis, AE; Raptis, SA; Tountas, NB; Yalouris, AG | 1 |
| Hodorek, MJ; Iannucci, AR; Peuler, JD; Phare, SM | 1 |
| Howes, LG; Lykos, D; Sundaresan, P | 1 |
| Boehmer, H; Borcea, V; Grauer, A; Heilmann, P; Hofmann, M; Kasperk, C; Nawroth, PP; Wahl, P; Ziegler, R; Zumbach, M | 1 |
| Cavallo, P; D'Argenzio, R; Merante, D; Morelli, A | 1 |
| Carmellini, M; Coppelli, A; Del Guerra, S; Giannarelli, R; Lorenzetti, M; Lupi, R; Marchetti, P; Mosca, F; Navalesi, R; Tellini, C | 2 |
| Daher, A; Diamond, T; Howes, LG; Lykos, D; Morris, R; Sundaresan, P | 1 |
| Ambrosi, F; Filipponi, P; Gregorio, F; Manfrini, S; Santucci, A | 1 |
| Bourghli, M; Miller, JA; Peuler, JD; Soltis, EE; Sowers, JR; Zammam, HY | 1 |
| Anderson, D; Briscoe, TA; Cooper, GS; Usifo, OS | 1 |
| Barrois, R; Candiloros, H; Denet, S; Donner, M; Drouin, P; Muller, S; Wiernsperger, N | 1 |
| Koyama, H; Mori, S; Nakajima, K; Sugioka, N; Uno, A | 1 |
| Abourizk, NN; al-Jebawi, AF; Lassman, MN | 1 |
| Piccolo, I; Sterzi, R; Thiella, G | 1 |
| Anello, M; Guardabasso, V; Italia, S; Licciardello, C; Mazzarino, S; Raimondo, M; Runello, F; Sangiorgi, L; Trischitta, V; Vigneri, R | 1 |
| Greenaway, TM; Peterson, GM; Randall, CT; Vial, JH; Yap, WS | 1 |
| Heikkilä, M; Nikkilä, K; Ryysy, L; Tulokas, T; Vanamo, R; Yki-Järvinen, H | 1 |
| Annemans, L; Hood, SC; Rutten-van Mölken, M | 1 |
| André, P | 1 |
| Awata, T; Chen, S; Katayama, S; Kosegawa, I; Negishi, K | 1 |
| Muzaffar, Z; Niazi, R | 1 |
| Bak, MI; Czyzyk, A; Dworak, A; Zapecka-Dubno, B | 1 |
| Coppini, A; Erle, G; Lora, L; Lovise, S; Marchetti, P; Merante, D; Stocchiero, C | 1 |
| Davidoff, AJ; Dominguez, LJ; Ren, J; Sowers, JR | 1 |
| Mjörndal, T; Spigset, O | 1 |
| Ambrosi, F; Carle, F; Filipponi, P; Gregorio, F; Manfrini, S; Merante, D; Testa, R; Velussi, M | 1 |
| Belch, JJ; Jennings, PE | 1 |
| Riddle, M | 1 |
| Hirschberg, Y; Karara, AH; McLeod, JF; Pietri, AO | 1 |
| Balan, G; Greene, DS; Marathe, PH; Timmins, P | 1 |
| Corrall, RJ; Hattersley, AT; Liddell, WG; Pearson, ER; Shepherd, M | 1 |
| Ling Fu, C; McCormick, KL; Mick, GJ; Wang, X | 1 |
| Arnold, ME; Barbhaiya, RH; Greene, DS; Marathe, PH; Meeker, J | 1 |
| Meneilly, GS; Tessier, D | 1 |
| Hermann, LS; Melander, A; Ranstam, J; Vaaler, S | 1 |
| Hanefeld, M; Naditch, L; Raptis, SA; Rybka, J; Schernthaner, G; Standl, E | 1 |
| Dubois-Laforgue, D; Timsit, J | 1 |
| Brunelli, C; Cordera, R; Cordone, S; Olivotti, L; Rossettin, P; Schiavo, M; Spallarossa, P | 1 |
| Adler, Y; Behar, S; Benderly, M; Boyko, V; Fisman, EZ; Friedensohn, A; Kohanovski, M; Motro, M; Rotzak, R; Schneider, H; Tenenbaum , A | 1 |
| Blonde, L; Sandberg, MI | 1 |
| Rutten, GE | 1 |
| Dornan, T; Hollis, S | 1 |
| Dornhorst, A | 1 |
| Seymour, A | 1 |
| Hayes, JD; Marchione, V; Mayes, K; Milgram, L; Roselli, A; Seidner, R; Snyder, CM; Stiernberg, CM | 1 |
| Boggi, U; Del Guerra, S; Del Prato, S; Fierabracci, V; Lupi, R; Marchetti, P; Marselli, L; Mosca, F; Novelli, M; Patanè, G; Piro, S | 1 |
| Abbink, EJ; Jansen van Rosendaal, A; Lutterman, JA; Pickkers, P; Russel, FG; Smits, P; Tack, CJ | 1 |
| Armstrong, D; Baxi, S; Caulfield, M; Chu, NV; Deutsch, R; Henry, RR; Kim, DD; Kong, AP; Mudaliar, SR; Reaven, PD; Reitz, R | 1 |
| Büyükafşar, K; çamdeviren, H; Kaygusuz, A; Levent, A; Polat, G; Un, I; Yazar, A | 1 |
| Chang, E; Dezii, CM; Melikian, C; Vanderplas, A; White, TJ | 1 |
| Garber, AJ; Henry, D; Larsen, J; Piper, BA; Schneider, SH | 1 |
| Braddon, J; Phillips, P | 1 |
| Allavoine, T; Howlett, H; Lehert, P; Marre, M | 1 |
| Berry, RA; Freed, MI; Greene, DA; Haffner, SM; Heise, MA; Herman, WH; Holman, RR; Jones, NP; Kahn, SE; Lachin, JM; Levy, D; Viberti, G; Zinman, B | 1 |
| Bruce, S; Fiedorek, FT; Garber, AJ | 1 |
| Dailey, GE; Fiedorek, FT; Mohideen, P | 1 |
| Blonde, L; Henry, D; Mooradian, AD; Piper, BA; Rosenstock, J | 1 |
| Khan, IA; Molnar, J; Najeed, SA; Somberg, JC | 1 |
| Mateos-García, E; Medina Santillán, R; Reyes-García, G | 2 |
| Glueck, CJ; Goldenberg, N; Streicher, P; Wang, P | 1 |
| Franzoso, F; Grasso, M; Scannapieco, G | 1 |
| Bokhari, SU; Duckworth, WC; Gopal, UM | 1 |
| Aroda, V; Bandukwala, R; Baxi, S; Carter, L; Ciaraldi, TP; Henry, RR; Kong, AP; Mudaliar, SR; Phillips, SA | 1 |
| Brown, JB; Nichols, GA | 1 |
| Bar, RS; Bayless, ML; Haynes, WG; Larson, LF; Sinkey, C; Sivitz, WI; Wayson, SM | 1 |
| Allavoine, T; Blonde, L; Cornes, M; Garber, A; Howlett, H; Lehert, P; Marre, M | 1 |
| Akbar, DH | 1 |
| Penfornis, A | 1 |
| Allavoine, T; Howlett, H; Kuhn, T; Nicholson, G; Porte, F | 1 |
| Antić, S; Bogicević, M; Milojković, M; Mitić-Zlatković, M; Stefanović, V; Stojiljković, S; Vlahović, P | 1 |
| Rochester, CD; Samuel, J | 1 |
| Guerrero-Romero, F; Rodríguez-Morán, M | 1 |
| Del Prato, S; Emmons, RP; Guitard, C; Heine, RJ; Keilson, L; Shen, SG | 1 |
| Bell, CF; Botteman, MF; Braunstein, SN; Devine, ST; Ramsdell, JW; Stephens, JM | 1 |
| Brun, E; Coppini, A; Gori, M; Moghetti, P; Muggeo, M; Perobelli, L; Spiazzi, G; Tosi, F; Zanolin, E | 1 |
| Dailey, GE | 1 |
| Nicklasson, L; Stockl, K; Vanderplas, AM | 1 |
| Bruce, S; Dandona, P; Donovan, DS; Garber, AJ; Park, JS | 1 |
| Scheen, AJ | 3 |
| Ferro, A; Goubareva, I; Ji, Y; Queen, LR | 1 |
| Blonde, L; Kreilick, C; Seymour, AA; Wogen, J | 1 |
| Bell, D; Bonow, RO; Fonseca, V; Grundy, SM; Horton, ES; Kahn, R; Le Winter, M; Nesto, RW; Porte, D; Semenkovich, CF; Smith, S; Young, LH | 1 |
| Aguilar-Cota, ME; Camacho, A; Flores-Murrieta, FJ; Herrera, JE; Medina-Santillán, R; Reyes-García, G | 1 |
| Campbell, RK; Iltz, JL; Setter, SM; Thams, J | 1 |
| Bruce, S; Dailey, GE; Fiedorek, FT; Noor, MA; Park, JS | 1 |
| Haslbeck, M; Jakob, S; Kellerer, M; Linn, T | 1 |
| Guevara, M; Guevara-Aguirre, J; Mihic, M; Modi, P; Saavedra, J | 1 |
| Abrahamson, MJ | 1 |
| Andrès, E; Goichot, B; Perrin, AE; Schlienger, JL; Vinzio, S | 1 |
| Abe, Y; Matsumoto, K; Miyake, S; Sera, Y; Tominaga, T; Yeki, Y | 1 |
| Chandalia, HB; Fafadia, A; Joshi, SR; Panikar, V; Santvana, C | 1 |
| Croom, DK; Lenhard, JM; Minnick, DT | 1 |
| Blonde, L; Henry, D; Howlett, H; Joyal, S | 1 |
| Bar, RS; Goldner, WS; Haynes, WG; Putz, DM; Sivitz, WI | 1 |
| Hayaishi-Okano, R; Hori, M; Kaneto, H; Katakami, N; Kosugi, K; Matsuhisa, M; Ohtoshi, K; Yamasaki, Y | 1 |
| Davidson, JA; Howlett, HC; Scheen, AJ | 1 |
| Aburuz, S; McElnay, J; Millership, J | 1 |
| Johnson, PJ; Kreeger, JM; Messer, NT; Scotty, NC; Wiedmeyer, C | 1 |
| Stiefelhagen, P | 1 |
| Alvarez Aguilar, C; Gómez García, A; Soto Paniagua, JG | 1 |
| Brunetti, P; Gori, M; Pagano, G; Perriello, G; Turco, C | 1 |
| Andrade-Cetto, A; Martínez-Zurita, E; Wiedenfeld, H | 1 |
| Fowler, A; Galiñanes, M; Hassouna, A; Loubani, M; Matata, BM; Standen, NB | 1 |
| Abramowitz, W; Chou, T; Rao, N; Ventura, D | 1 |
| Einarson, TR; Leiter, LA; MacKeigan, LD; Sadri, H | 1 |
| Hilberg, C; Kvapil, M; Shestakova, M; Swatko, A | 1 |
| Cobitz, AR; Freed, MI; Rood, JA; Ryan, CM; Strachan, MW; Waterhouse, BR | 1 |
| Bruce, S; Garber, A; Klein, E; Mohideen, P; Sankoh, S | 1 |
| Koeppe, J; Kosmiski, L | 1 |
| Colette, C; Lapinski, H; Monnier, L; Thuan, JF | 1 |
| Lofsky, S | 1 |
| Feng, SY; Lai, EP | 1 |
| Anant, M; Ekstrøm, CT; Hansen, L; Reinhardt, RR; Tabanera Y Palacios, R; Wassermann, K | 1 |
| Bruce, S; Fiedorek, FT; Howlett, HC; Park, JS | 1 |
| Forst, T; Hanefeld, M; Lübben, G; Pfützner, A | 1 |
| Almoznino-Sarafian, D; Alon, I; Berman, S; Cohen, N; Efrati, S; Gorelik, O; Shteinshnaider, M; Weissgarten, J | 1 |
| Barnett, AH; Dreyer, M; Lange, P; Serdarevic-Pehar, M | 1 |
| Dorkhan, M; Frid, A; Groop, L; Grubb, A; Jovinge, S; Magnusson, M | 1 |
| Cadenas, J; Facta, AD; Hsueh, WA; Prior, JO; Quinones, MJ; Schelbert, HR; Schindler, TH | 1 |
| Bakris, GL; Freed, MI; Heise, MA; McMorn, SO; Porter, LE; Ruilope, LM; Weston, WM | 1 |
| Freed, MI; Haffner, S; Heise, MA; Herman, WH; Holman, R; Jones, NP; Kahn, SE; Kravitz, B; Lachin, J; O'Neill, MC; Viberti, G; Zinman, B | 1 |
| Haffner, SM; Heise, MA; Herman, WH; Holman, RR; Jones, NP; Kahn, SE; Kravitz, BG; Lachin, JM; O'Neill, MC; Viberti, G; Zinman, B | 1 |
| Nathan, DM | 1 |
| Abreu-Pacheco, H; Kanna, B | 1 |
| Bacardi-Gascon, M; Dueñas-Mena, D; Jimenez-Cruz, A | 1 |
| Hasan, R; Javaid, A; Mansoor, S; Zaib, A | 1 |
| Correa, MR; Cunha, MR; da Silva, ME; Fukui, RT; Machado, HA; Negrão, CE; Rondon, MU; Santos, RF; Ursich, MJ; Wajchenberg, BL | 1 |
| Garg, R | 1 |
| Albu, F; David, V; Georgita, C; Medvedovici, A | 1 |
| Willeke, A | 1 |
| Coustan, DR | 1 |
| Einecke, D | 1 |
| Jangid, AG; Mistri, HN; Shrivastav, PS | 1 |
| Matthaei, S | 1 |
| Lewin, A; Lipetz, R; Schwartz, S; Wu, J | 1 |
| Bellatreccia, A; Comaschi, M; Demicheli, A; Di Pietro, C; Mariz, S | 1 |
| Bellatreccia, A; Comaschi, M; Corsi, A; Di Pietro, C; Mariz, S | 1 |
| Baron, MA; Gerich, JE; Jean-Louis, L; Marcellari, A; Purkayastha, D; Schwarz, SL | 1 |
| Atkinson, LL; Benkoczi, C; Finegood, DT; McDonald-Dyck, C | 1 |
| Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Fogari, E; Gravina, A; Salvadeo, S | 2 |
| Bank, AJ; Gonzalez-Campoy, JM; Kaiser, DR; Kelly, AS; Thelen, AM | 1 |
| Chang, CT; Chien, HH; Chu, NF; Hsieh, SH; Huang, YY; Lee, IT; Lee, WJ; Sheu, WH; Tang, YJ | 1 |
| Cabrales, P; Díaz, JS; Intaglietta, M; Negrete, AC; Salazar Vázquez, BY; Salazar Vázquez, MA; Venzor, VC | 1 |
| Kleinwechter, H; Schaefer-Graf, UM | 1 |
| Aftring, RP; Haffner, SM; Heise, MA; Herman, WH; Holman, RR; Kahn, SE; Kravitz, BG; Lachin, JM; Viberti, G; Yu, D; Zinman, B | 1 |
| Schnell, O; Standl, E | 1 |
| Dachs, R; Darby-Stewart, A; Graber, MA | 1 |
| Correia, MR; Cunha, MR; Fukui, RT; Machado, HA; Negrão, CE; Rocha, DM; Rondon, MU; Santos, RF; Silva, ME; Ursich, MJ; Wajchenberg, BL | 1 |
| Chernew, ME; Fendrick, AM; Pan, F | 1 |
| Krishnarajah, G; Lyu, R; Mavros, P; Vexiau, P; Yin, D | 1 |
| Iwao, K; Kawai, RT; Kobayashi, M; Oda, M; Saitoh, H | 1 |
| Mogensen, CE; Sadikot, SM | 1 |
| De Mattia, G; Laurenti, O; Moretti, A | 1 |
| Balzi, D; Lamanna, C; Mannucci, E; Marchionni, N; Monami, M | 1 |
| Bass, E; Bolen, S; Neale, D; Nicholson, W; Wilson, L; Witkop, CT | 1 |
| Arnold Chan, K; Dore, DD; Seeger, JD | 1 |
| Car, N; Hancu, N; Ivanyi, T; Jermendy, G; Milicevic, Z; Schwarzenhofer, M | 1 |
| Cheung, NW | 1 |
| Chevalier, S; Gougeon, R; Lamarche, M; Morais, JA; Mourad, C | 1 |
| Adams-Huet, B; Kaloyanova, PF; Legendre, JL; Lingvay, I; Raskin, P; Zhang, S | 1 |
| Coustan, DR; Paglia, MJ | 1 |
| McGill, JB | 1 |
| de Valk, HW | 1 |
| Dhillon, S; Weber, J | 1 |
| Haffner, SM; Herman, WH; Holman, RR; Kahn, SE; Kravitz, BG; Lachin, JM; Paul, G; Viberti, G; Yu, D; Zinman, B | 1 |
| Aftring, RP; Haffner, SM; Herman, WH; Holman, RR; Jones, NP; Kahn, SE; Kravitz, BG; Lachin, JM; Paul, G; Viberti, G; Zinman, B | 1 |
| Clokey, D; Curet, LB; Moore, LE; Rappaport, VJ | 1 |
| Aragão, DM; da Costa, JC; Garcia, RM; Guarize, L; Lanini, J; Scio, E | 1 |
| Ciccarelli, L; Cicero, AF; D'Angelo, A; Derosa, G; Ferrari, I; Franzetti, IG; Gadaleta, G; Maffioli, P; Piccinni, MN; Querci, F; Ragonesi, PD; Salvadeo, SA | 1 |
| Ahmed, MS; Hankins, GD; Hemauer, SJ; Nanovskaya, TN; Patrikeeva, SL | 1 |
| Boston, RC; Cottle, HJ; Durham, AE; Hughes, KJ; Rendle, DI | 1 |
| Bertini, AM; Bizato, J; de Souza, BV; Pacheco, C; Ribeiro, TE; Silva, JC | 1 |
| Erejuwa, OO; Gurtu, S; Salam, SK; Salleh, MS; Sulaiman, SA; Wahab, MS | 2 |
| Barbieri, M; Boccardi, V; Canonico, S; Lettieri, B; Marfella, R; Paolisso, G; Rizzo, MR; Vestini, F | 1 |
| Dhulkotia, JS; Farrell, T; Fraser, R; Ola, B | 1 |
| Kirana, H; Srinivasan, BP | 1 |
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79 review(s) available for glyburide and metformin
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Behavior of lactate and pyruvate in diabetics during ambulatory treatment with biguanides or with a combination of biguanides and sulfonylureas. II].
Topics: Aged; Ambulatory Care; Biguanides; Diabetes Mellitus; Diabetic Ketoacidosis; Drug Combinations; Female; Glyburide; Humans; Lactates; Male; Metformin; Middle Aged; Phenformin; Pyruvates; Sulfonylurea Compounds | 1980 |
Metformin: a new treatment option for non-insulin-dependent diabetes mellitus.
Topics: Biguanides; Diabetes Mellitus, Type 2; Drug Interactions; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Sulfonylurea Compounds | 1996 |
Cardiovascular effects of oral hypoglycaemic drugs.
Topics: Biguanides; Diabetes Mellitus, Type 2; Glyburide; Heart; Hemodynamics; Humans; Hypoglycemic Agents; Lipoproteins; Metformin; Myocardial Contraction; Potassium Channel Blockers; Stimulation, Chemical; Sulfonylurea Compounds; Tolbutamide | 1996 |
[The Wolfram syndrome: diabetes mellitus, hypacusis, optic atrophy and short stature in STH deficiency].
Topics: Adult; Drug Therapy, Combination; Glyburide; Growth Disorders; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Wolfram Syndrome | 1997 |
Combining sulfonylureas and other oral agents.
Topics: Acarbose; Administration, Oral; Carbamates; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Metformin; Piperidines; Sulfonylurea Compounds | 2000 |
Diabetes in elderly adults.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Diet Therapy; Exercise; Female; Glyburide; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Risk Factors; Rosiglitazone; Thiazoles; Thiazolidinediones; United States | 2001 |
[Should the occurrence of a first coronary event change the management of diabetes?].
Topics: Acidosis, Lactic; Acute Disease; Adrenergic beta-Antagonists; Blood Glucose; Cardiovascular Agents; Case Management; Cohort Studies; Controlled Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Incidence; Insulin; Metformin; Myocardial Infarction; Obesity; Prospective Studies; Randomized Controlled Trials as Topic; Risk; Sulfonylurea Compounds; Treatment Outcome | 2000 |
[Repaglinide, potentially a therapeutic improvement for diabetes mellitus type 2].
Topics: Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Metformin; Piperidines; Therapeutic Equivalency | 2001 |
Critical appraisal of published research evidence: treatment of gestational diabetes.
Topics: Attitude of Health Personnel; Clinical Trials as Topic; Diabetes, Gestational; Evidence-Based Medicine; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Placenta; Pregnancy; Surveys and Questionnaires | 2001 |
Glyburide/metformin HCl clinical overview.
Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Combinations; Glyburide; Glycated Hemoglobin; Health Care Costs; Humans; Hypoglycemic Agents; Metformin; United States | 2001 |
Oral hypoglycaemics. When not to use what.
Topics: Acarbose; Acidosis, Lactic; Aged; Contraindications; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Pioglitazone; Renal Insufficiency; Rosiglitazone; Thiazoles; Thiazolidinediones | 2002 |
The contentious nature of gestational diabetes: diet, insulin, glyburide and metformin.
Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Polycystic Ovary Syndrome; Pregnancy | 2002 |
Influence of initial hyperglycaemia, weight and age on the blood glucose lowering efficacy and incidence of hypoglycaemic symptoms with a single-tablet metformin-glibenclamide therapy (Glucovance) in type 2 diabetes.
Topics: Age Factors; Aged; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Metformin; Middle Aged; Randomized Controlled Trials as Topic | 2003 |
[Drug compliance in type 2 diabetes: role of drug treatment regimens and consequences on their benefits].
Topics: Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Metformin; Patient Compliance; Patient Education as Topic; Prognosis | 2003 |
Combination agents for diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Drug Combinations; Female; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Thiazoles; Thiazolidinediones | 2003 |
Treatment of patients over 64 years of age with type 2 diabetes: experience from nateglinide pooled database retrospective analysis.
Topics: Aged; Blood Glucose; Body Mass Index; Comorbidity; Cyclohexanes; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Metformin; Nateglinide; Phenylalanine; Randomized Controlled Trials as Topic; Retrospective Studies | 2003 |
Glyburide/metformin tablets: a new therapeutic option for the management of Type 2 diabetes.
Topics: Clinical Trials as Topic; Cost of Illness; Diabetes Mellitus, Type 2; Drug Combinations; Glyburide; Humans; Hypoglycemic Agents; Metformin; Randomized Controlled Trials as Topic; Tablets | 2003 |
[Medication of the month. Glucovance in type 2 diabetes, a fixed combination of metformin-glibenclamide for the treatment of a bipolar metabolic disease].
Topics: Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Patient Compliance; Periodicity | 2003 |
Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003.
Topics: Blood Volume; Clinical Trials as Topic; Comorbidity; Contraindications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Edema; Glyburide; Heart Failure; Humans; Hypoglycemic Agents; Insulin; Metformin; Risk Factors; Safety; Thiazolidinediones; Weight Gain | 2003 |
Metformin hydrochloride in the treatment of type 2 diabetes mellitus: a clinical review with a focus on dual therapy.
Topics: Clinical Trials as Topic; Contraindications; Diabetes Mellitus, Type 2; Drug Interactions; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones | 2003 |
[Continuation 50. Type 2 diabetes: possibilities and limitations of pharmacological therapy].
Topics: 1-Deoxynojirimycin; Acarbose; Aged; Blood Glucose; Carbamates; Contraindications; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Fasting; Follow-Up Studies; Germany; Glucosamine; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemia; Hypoglycemic Agents; Imino Pyranoses; Insulin; Metformin; Middle Aged; Nateglinide; Obesity; Patient Compliance; Phenylalanine; Pioglitazone; Piperidines; Practice Guidelines as Topic; Risk Factors; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Time Factors | 2003 |
Tolerability profile of metformin/glibenclamide combination tablets (Glucovance): a new treatment for the management of type 2 diabetes mellitus.
Topics: Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Glyburide; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Lipids; Metformin; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Tablets; Time Factors; Treatment Outcome | 2004 |
Pharmacological management of gestational diabetes: an overview.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Metformin; Pregnancy | 2007 |
Diagnosis and new approaches in the therapy of gestational diabetes mellitus.
Topics: Blood Glucose; Diabetes, Gestational; Female; Fetal Development; Fetus; Glyburide; Humans; Hypoglycemic Agents; Metformin; Polycystic Ovary Syndrome; Pregnancy | 2006 |
Benefits and risks of oral diabetes agents compared with insulin in women with gestational diabetes: a systematic review.
Topics: Acarbose; Administration, Oral; Birth Weight; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy | 2009 |
The management of gestational diabetes.
Topics: Administration, Oral; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes, Gestational; Drug Administration Schedule; Exercise; Female; Fetus; Glyburide; Humans; Hypoglycemic Agents; Injections; Insulin; Metformin; Postpartum Period; Pregnancy; Pregnancy Outcome; Treatment Outcome | 2009 |
The use of oral antidiabetic medications in gestational diabetes mellitus.
Topics: Administration, Oral; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Metformin; Pregnancy | 2009 |
Selecting among ADA/EASD tier 1 and tier 2 treatment options.
Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Glyburide; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Male; Metformin; Practice Guidelines as Topic; Prognosis; Risk Assessment; Rosiglitazone; Severity of Illness Index; Thiazolidinediones; Treatment Outcome | 2009 |
Oral hypoglycemic agents vs insulin in management of gestational diabetes: a systematic review and metaanalysis.
Topics: Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy Outcome; Randomized Controlled Trials as Topic | 2010 |
Oral hypoglycemic agents for gestational diabetes mellitus?
Topics: Administration, Oral; Animals; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Quality of Life | 2011 |
Oral hypoglycaemic agents during pregnancy: The evidence for effectiveness and safety.
Topics: Acarbose; Administration, Oral; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy; Pregnancy Outcome; Randomized Controlled Trials as Topic; Treatment Outcome | 2011 |
Linagliptin for the treatment of type 2 diabetes (pharmacokinetic evaluation).
Topics: Area Under Curve; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Glyburide; Humans; Hypoglycemic Agents; Linagliptin; Metformin; Pioglitazone; Purines; Quinazolines; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiazolidinediones | 2011 |
Management of diabetes in pregnancy.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Mass Screening; Metformin; Practice Guidelines as Topic; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome | 2012 |
[Drug therapy for diabetes mellitus during pregnancy and breastfeeding in the beginning of 21 century: status quo and new challenges].
Topics: Breast Feeding; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulins; Metformin; Pregnancy | 2012 |
Abnormal glucose metabolism: diagnosis and management in the ambulatory setting.
Topics: Ambulatory Care; Blood Glucose Self-Monitoring; Diabetes, Gestational; Diet Therapy; Exercise Therapy; Female; Glucose Intolerance; Glucose Tolerance Test; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy Complications; Pregnancy in Diabetics; Prenatal Care; Risk Factors | 2012 |
Momordica charantia for type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Metformin; Momordica charantia; Phytotherapy; Plant Extracts; Randomized Controlled Trials as Topic | 2012 |
Combination of glibenclamide-metformin HCl for the treatment of type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Drug Combinations; Glyburide; Humans; Hypoglycemic Agents; Metformin; Treatment Outcome | 2012 |
Clinically relevant reductions in HbA1c without hypoglycaemia: results across four studies of saxagliptin.
Topics: Adamantane; Area Under Curve; Controlled Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptides; Drug Therapy, Combination; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Treatment Outcome | 2013 |
Oral agents for the management of gestational diabetes.
Topics: Administration, Oral; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Metformin; Pregnancy | 2013 |
Unresolved controversies in gestational diabetes: implications on maternal and infant health.
Topics: Caloric Restriction; Diabetes, Gestational; Diet, Carbohydrate-Restricted; Diet, Diabetic; Female; Fetal Development; Gene Expression Regulation, Developmental; Glyburide; Humans; Hypoglycemic Agents; Infant; Infant, Newborn; Maternal-Child Health Centers; Maternal-Fetal Exchange; Metformin; Pregnancy; Pregnancy Outcome; United States | 2014 |
Efficacy and safety of oral antidiabetic drugs in comparison to insulin in treating gestational diabetes mellitus: a meta-analysis.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Treatment Outcome | 2014 |
Gestational diabetes mellitus management with oral hypoglycemic agents.
Topics: Administration, Oral; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy Outcome | 2014 |
Screening and management of gestational diabetes.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 2; Diabetes, Gestational; Diet, Diabetic; Disease Management; Exercise Therapy; Female; Glucose Tolerance Test; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy in Diabetics; Prenatal Diagnosis | 2015 |
Safety considerations with pharmacological treatment of gestational diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Life Style; Metformin; Pregnancy; Randomized Controlled Trials as Topic | 2015 |
Glibenclamide, metformin, and insulin for the treatment of gestational diabetes: a systematic review and meta-analysis.
Topics: Adult; Birth Weight; Diabetes, Gestational; Female; Fetal Macrosomia; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy; Pregnancy Outcome; Randomized Controlled Trials as Topic; Regression Analysis | 2015 |
Using oral agents to manage gestational diabetes: what have we learned?
Topics: Acarbose; Administration, Oral; Birth Weight; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Metformin; Practice Guidelines as Topic; Pregnancy; Treatment Outcome | 2015 |
Comparative efficacy and safety of OADs in management of GDM: network meta-analysis of randomized controlled trials.
Topics: Administration, Oral; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy Outcome; Randomized Controlled Trials as Topic; Treatment Outcome | 2015 |
Comparison of glyburide with metformin in treating gestational diabetes mellitus: a systematic review and meta-analysis.
Topics: Adult; Birth Weight; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Metformin; Pregnancy | 2015 |
Systematic review and meta-analysis of the efficacy and hypoglycemic safety of gliclazide versus other insulinotropic agents.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Gliclazide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Middle Aged; Randomized Controlled Trials as Topic; Sulfonylurea Compounds; Treatment Outcome; Young Adult | 2015 |
Is it worth treating gestational diabetes: if so, when and how?
Topics: Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Metformin; Pregnancy; Pregnancy Complications | 2016 |
Pharmacological Management of Gestational Diabetes Mellitus.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2016 |
Oral anti-diabetic pharmacological therapies for the treatment of women with gestational diabetes.
Topics: Acarbose; Administration, Oral; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Pregnancy; Randomized Controlled Trials as Topic; Tolbutamide | 2017 |
Enemies or weapons in hands: investigational anti-diabetic drug glibenclamide and cancer risk.
Topics: Animals; ATP-Binding Cassette Transporters; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; KATP Channels; Metformin; Neoplasms; Risk | 2017 |
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia.
Topics: Carbamates; Cause of Death; Cognition Disorders; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Memory Disorders; Metformin; Piperidines; Randomized Controlled Trials as Topic; Rosiglitazone; Thiazolidinediones | 2017 |
Treatments for gestational diabetes: a systematic review and meta-analysis.
Topics: Bayes Theorem; Cesarean Section; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy Outcome; Randomized Controlled Trials as Topic | 2017 |
The care of pregestational and gestational diabetes and drug metabolism considerations.
Topics: Animals; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy in Diabetics | 2017 |
Pharmacological Management of Gestational Diabetes Mellitus.
Topics: Acarbose; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2017 |
Comparative efficacy and safety of oral antidiabetic drugs and insulin in treating gestational diabetes mellitus: An updated PRISMA-compliant network meta-analysis.
Topics: Administration, Oral; Adult; Blood Glucose; Comparative Effectiveness Research; Diabetes, Gestational; Female; Fetal Macrosomia; Glyburide; Humans; Hypoglycemic Agents; Incidence; Infant, Newborn; Insulin; Metformin; Pregnancy; Randomized Controlled Trials as Topic | 2017 |
Metformin for prevention of hypertensive disorders of pregnancy in women with gestational diabetes or obesity: systematic review and meta-analysis of randomized trials.
Topics: Bayes Theorem; Diabetes, Gestational; Female; Glyburide; Humans; Hypertension, Pregnancy-Induced; Incidence; Metformin; Obesity; Pre-Eclampsia; Pregnancy; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Efficacy of different antidiabetic drugs based on metformin in the treatment of type 2 diabetes mellitus: A network meta-analysis involving eight eligible randomized-controlled trials.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Drug Combinations; Exenatide; Female; Glyburide; Humans; Male; Metformin; Network Meta-Analysis; Pioglitazone; Randomized Controlled Trials as Topic; Rosiglitazone; Sulfonylurea Compounds; Vildagliptin | 2019 |
Oral Agents for the Treatment of Gestational Diabetes.
Topics: Administration, Oral; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2018 |
Reflections on the sulphonylurea story: A drug class at risk of extinction or a drug class worth reviving?
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Gliclazide; Glipizide; Glucagon-Like Peptide-1 Receptor; Glyburide; History, 20th Century; History, 21st Century; Humans; Hypoglycemic Agents; Insulin Secretion; Insulin-Secreting Cells; Metformin; Sodium-Glucose Transporter 2 Inhibitors; Sulfonylurea Compounds; Treatment Failure | 2019 |
Pharmacologic Treatment of Diabetes in Pregnancy.
Topics: Diabetes, Gestational; Exercise; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy in Diabetics; Prenatal Care | 2019 |
Comparative Efficacy and Safety of Metformin, Glyburide, and Insulin in Treating Gestational Diabetes Mellitus: A Meta-Analysis.
Topics: Adult; Biomarkers; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Patient Safety; Pregnancy; Randomized Controlled Trials as Topic; Risk Assessment; Treatment Outcome; Young Adult | 2019 |
The Use of Non-insulin Agents in Gestational Diabetes: Clinical Considerations in Tailoring Therapy.
Topics: Acarbose; Diabetes, Gestational; Female; Glyburide; Healthy Lifestyle; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Prenatal Exposure Delayed Effects | 2019 |
Gestational Diabetes Mellitus Pharmacological Prevention and Treatment.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2021 |
Metformin is comparable to insulin for pharmacotherapy in gestational diabetes mellitus: A network meta-analysis evaluating 6046 women.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Treatment Outcome | 2021 |
Comparison of Insulin, Metformin, and Glyburide on Perinatal Complications of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis.
Topics: Cesarean Section; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy | 2021 |
Effectiveness of antidiabetic agents for treatment of gestational diabetes: A methodological quality assessment of meta-analyses and network meta-analysis.
Topics: Adult; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Meta-Analysis as Topic; Metformin; Network Meta-Analysis; Pregnancy; Pregnancy Outcome; Reproducibility of Results; Research Design; Treatment Outcome | 2021 |
Gestational diabetes: Implications for fetal growth, intervention timing, and treatment options.
Topics: Diabetes, Gestational; Female; Fetal Development; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy | 2021 |
Glycemic control and neonatal outcomes in women with gestational diabetes mellitus treated using glyburide, metformin, or insulin: a pairwise and network meta-analysis.
Topics: Adult; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Glycemic Control; Humans; Hypoglycemic Agents; Infant, Newborn; Infant, Newborn, Diseases; Insulin; Male; Matched-Pair Analysis; Metformin; Network Meta-Analysis; Pregnancy; Pregnancy Outcome; Randomized Controlled Trials as Topic | 2021 |
Comparison of the effectiveness and safety of insulin and oral hypoglycemic drugs in the treatment of gestational diabetes mellitus: a meta-analysis of 26 randomized controlled trials.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy; Randomized Controlled Trials as Topic | 2022 |
Creatine Supplementation in Type 2 Diabetic Patients: A Systematic Review of Randomized Clinical Trials.
Topics: Blood Glucose; Creatine; Diabetes Mellitus, Type 2; Dietary Supplements; Glyburide; Humans; Hypoglycemic Agents; Metformin; Randomized Controlled Trials as Topic | 2022 |
Metformin versus glyburide in treatment and control of gestational diabetes mellitus: a systematic review with meta-analysis.
Topics: Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy | 2022 |
Incretins as a Potential Treatment Option for Gestational Diabetes Mellitus.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Diabetes, Gestational; Dipeptidyl-Peptidase IV Inhibitors; Female; Glucagon-Like Peptide 1; Glyburide; Humans; Hypoglycemic Agents; Incretins; Metformin; Pregnancy | 2022 |
Availability and affordability of essential medicines and diagnostic tests for diabetes mellitus in Africa.
Topics: Costs and Cost Analysis; Diabetes Mellitus; Diagnostic Tests, Routine; Drugs, Essential; Glyburide; Glycated Hemoglobin; Health Services Accessibility; Humans; Insulin; Insulin, Short-Acting; Lipids; Metformin | 2022 |
Medications for Managing Preexisting and Gestational Diabetes in Pregnancy.
Topics: Child; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2023 |
131 trial(s) available for glyburide and metformin
| Article | Year |
|---|---|
Insulin, glibenclamide or metformin treatment for non insulin dependent diabetes: heterogenous responses of standard measures of insulin action and insulin secretion before and after differing hypoglycaemic therapy.
Topics: Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Glucose Clamp Technique; Glyburide; Glycated Hemoglobin; Glycosuria; Humans; Insulin; Insulin Resistance; Insulin Secretion; Metabolic Clearance Rate; Metformin; Middle Aged; Radioisotope Dilution Technique; Tritium | 1992 |
Comparison of combined therapies in treatment of secondary failure to glyburide.
Topics: Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; Eating; Fasting; Glyburide; Glycated Hemoglobin; Humans; Insulin, Isophane; Metformin; Middle Aged; Obesity | 1992 |
[Evaluation of the efficacy of metformin-glibenclamide treatment in overweight non-insulin dependent diabetics].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Humans; Insulin; Metformin; Middle Aged; Obesity; Time Factors | 1992 |
Effectiveness of glibenclamide on myocardial ischemic ventricular arrhythmias in non-insulin-dependent diabetes mellitus.
Topics: Adult; Angina Pectoris; Blood Glucose; Cardiac Complexes, Premature; Coronary Disease; Diabetes Mellitus, Type 2; Electrocardiography, Ambulatory; Glyburide; Heart Rate; Humans; Male; Metformin; Middle Aged; Myocardial Infarction; Placebos; Tachycardia; Time Factors; Ventricular Function | 1991 |
Metformin causes a reduction in basal and post-venous occlusion plasminogen activator inhibitor-1 in type 2 diabetic patients.
Topics: alpha-Macroglobulins; Blood Glucose; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Drug Therapy, Combination; Fibrinolysin; Fibrinolysis; Glyburide; Glycated Hemoglobin; Hemostasis; Humans; Metformin; Middle Aged; Plasminogen Inactivators; Veins | 1991 |
Prospective comparative study in NIDDM patients of metformin and glibenclamide with special reference to lipid profiles.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Cholesterol; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Insulin; Insulin Secretion; Lipids; Lipoproteins; Male; Metformin; Middle Aged; Prospective Studies; Triglycerides | 1991 |
Effects of metformin and glibenclamide alone and in combination on serum lipids and lipoproteins in patients with non-insulin-dependent diabetes mellitus.
Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Humans; Lipids; Lipoproteins; Male; Metformin; Middle Aged | 1991 |
The effects of oral hypoglycaemic drugs on serum lipids and lipoproteins in non-insulin-dependent diabetes (NIDDM).
Topics: Administration, Oral; Blood Glucose; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Lipids; Lipoproteins; Longitudinal Studies; Male; Metformin; Triglycerides | 1991 |
Comparative efficacy of metformin and glibenclamide in patients with non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Humans; Male; Metformin; Middle Aged | 1991 |
Treatment of NIDDM patients with secondary failure to glyburide: comparison of the addition of either metformin or bed-time NPH insulin to glyburide.
Topics: Adult; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Humans; Insulin; Metformin; Middle Aged; Time Factors | 1991 |
Insulin and sulphonylurea in the therapy of type 2 diabetes.
Topics: Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Insulin; Lipids; Male; Metformin; Middle Aged; Placebos; Random Allocation; Sulfonylurea Compounds | 1990 |
Different effects of insulin and oral antidiabetic agents on glucose and energy metabolism in type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Blood Glucose; Blood Glucose Self-Monitoring; Body Weight; Cholesterol; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Energy Metabolism; Female; Glucose; Glucose Clamp Technique; Glyburide; Humans; Insulin; Insulin Infusion Systems; Liver; Male; Metformin; Middle Aged; Random Allocation; Reference Values | 1989 |
U.K. prospective diabetes study. II. Reduction in HbA1c with basal insulin supplement, sulfonylurea, or biguanide therapy in maturity-onset diabetes. A multicenter study.
Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin, Long-Acting; Male; Metformin; Middle Aged; Obesity; Random Allocation | 1985 |
The effect of glibenclamide and metformin on serum lipoproteins in type 2 diabetes.
Topics: Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Glyburide; Humans; Lipoproteins; Metformin; Random Allocation; Triglycerides | 1988 |
Platelet behaviour in non-insulin-dependent diabetes--influence of vascular complications, treatment and metabolic control.
Topics: Adenosine Diphosphate; Blood Platelets; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Epinephrine; Female; Glyburide; Humans; In Vitro Techniques; Insulin; Male; Metformin; Middle Aged; Serotonin | 1986 |
Serum C-peptide after 6 months on glibenclamide remains higher than during insulin treatment.
Topics: Adult; Aged; C-Peptide; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Insulin; Male; Metformin; Middle Aged; Time Factors | 1987 |
The difficult choice of treatment for poorly controlled maturity onset diabetes: tablets or insulin?
Topics: Adult; Aged; Attitude to Health; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Insulin, Long-Acting; Male; Metformin; Middle Aged; Prospective Studies; Random Allocation; Tablets | 1984 |
Comparison of insulin with or without continuation of oral hypoglycemic agents in the treatment of secondary failure in NIDDM patients.
Topics: Analysis of Variance; Biomarkers; Blood Glucose; Body Mass Index; C-Peptide; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Fructosamine; Gliclazide; Glipizide; Glyburide; Glycated Hemoglobin; Hexosamines; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Treatment Failure; Triglycerides | 1995 |
Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group.
Topics: Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Fasting; Female; Folic Acid; Glucose Tolerance Test; Glyburide; Glycated Hemoglobin; Humans; Insulin; Lactates; Lactic Acid; Male; Metformin; Middle Aged; Obesity; Treatment Failure; Vitamin B 12 | 1995 |
Therapeutic comparison of metformin and sulfonylurea, alone and in various combinations. A double-blind controlled study.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Insulin; Lipids; Male; Metformin; Middle Aged | 1994 |
United Kingdom Prospective Diabetes Study (UKPDS). 13: Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years.
Topics: Adult; Aged; Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glyburide; Glycated Hemoglobin; Humans; Insulin; Male; Metformin; Middle Aged; Obesity; Patient Compliance; Sulfonylurea Compounds | 1995 |
Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glyburide; Humans; Hyperglycemia; Male; Metformin; Middle Aged | 1994 |
Metabolic and hemodynamic effects of metformin and glibenclamide in normotensive NIDDM patients.
Topics: Biomarkers; Blood Glucose; Blood Pressure; Cardiac Output; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Fructosamine; Glyburide; Glycated Hemoglobin; Heart Rate; Hemodynamics; Hexosamines; Humans; Male; Metformin; Middle Aged; Posture; Triglycerides; Vascular Resistance | 1993 |
Daytime glibenclamide and bedtime NPH insulin compared to intensive insulin treatment in secondary sulphonylurea failure: a 1-year follow-up.
Topics: Aged; Albuminuria; Analysis of Variance; Blood Glucose; Body Mass Index; C-Peptide; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin, Isophane; Insulin, Regular, Pork; Male; Metformin; Middle Aged; Sulfonylurea Compounds; Treatment Failure; Triglycerides | 1996 |
Therapeutic effect of glibenclamide in a fixed combination with metformin or phenformin in NIDDM patients.
Topics: Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Lipids; Male; Metformin; Middle Aged; Phenformin; Prospective Studies | 1996 |
Comparative effects of glibenclamide and metformin on ambulatory blood pressure and cardiovascular reactivity in NIDDM.
Topics: Acetylcholine; Adult; Aged; Angiotensin II; Blood Glucose; Blood Pressure; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Diazoxide; Double-Blind Method; Female; Forearm; Glyburide; Heart Rate; Hemodynamics; Humans; Hypoglycemic Agents; Infusions, Intra-Arterial; Lipoproteins; Male; Metformin; Middle Aged; Nitroprusside; Norepinephrine; Regional Blood Flow; Vascular Resistance | 1997 |
Meformin, plasma glucose and free fatty acids in type II diabetic out-patients: results of a clinical study.
Topics: Blood Glucose; Body Constitution; Body Mass Index; C-Peptide; Cholesterol; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Fatty Acids, Nonesterified; Female; Gliclazide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipoprotein(a); Male; Metformin; Middle Aged; Regression Analysis; Sex Characteristics | 1997 |
UKPDS 28: a randomized trial of efficacy of early addition of metformin in sulfonylurea-treated type 2 diabetes. U.K. Prospective Diabetes Study Group.
Topics: Blood Glucose; Blood Pressure; Chlorpropamide; Cholesterol; Clinical Protocols; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Patient Compliance; Sulfonylurea Compounds; Triglycerides; United Kingdom | 1998 |
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group.
Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Obesity; Prospective Studies; Risk Factors | 1998 |
Efficacy of combined treatments in NIDDM patients with secondary failure to sulphonylureas. Is it predictable?
Topics: Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Resistance; Drug Therapy, Combination; Fasting; Female; Food; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Sulfonylurea Compounds | 1998 |
Comparison of bedtime insulin regimens in patients with type 2 diabetes mellitus. A randomized, controlled trial.
Topics: Albuminuria; Blood Glucose; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Lipids; Metformin; Middle Aged; Weight Gain | 1999 |
Comparison of bedtime NPH insulin or metformin combined with glibenclamide in secondary sulphonylurea failure in obese type II (NIDDM) patients.
Topics: Adult; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Prospective Studies; Treatment Outcome | 1998 |
Effect of oral antidiabetic agents on plasma amylin level in patients with non-insulin-dependent diabetes mellitus (type 2).
Topics: Adult; Amyloid; Blood Glucose; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Male; Metformin | 1999 |
A comparison of preconstituted, fixed combinations of low-dose glyburide plus metformin versus high-dose glyburide alone in the treatment of type 2 diabetic patients.
Topics: Blood Glucose; Body Weight; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Postprandial Period; Time Factors | 1999 |
Poorly controlled elderly Type 2 diabetic patients: the effects of increasing sulphonylurea dosages or adding metformin.
Topics: Aged; Aging; Antithrombin III; Blood Glucose; Blood Platelets; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Fibrinolysis; Gliclazide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Thrombin | 1999 |
Free radical scavenging activity of sulfonylureas: a clinical assessment of the effect of gliclazide.
Topics: Adult; Aged; Blood Platelets; Collagen; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Free Radical Scavengers; Gliclazide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Oxidation-Reduction; Sulfonylurea Compounds | 2000 |
Improved control of mealtime glucose excursions with coadministration of nateglinide and metformin.
Topics: Adult; Aged; Blood Glucose; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; Eating; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Nateglinide; Phenylalanine; Postprandial Period | 2000 |
In-vitro in-vivo correlation models for glibenclamide after administration of metformin/glibenclamide tablets to healthy human volunteers.
Topics: Adult; Cross-Over Studies; Drug Interactions; Glyburide; Humans; Hypoglycemic Agents; Metformin; Models, Biological; Tablets | 2000 |
Pharmacokinetics and bioavailability of a metformin/glyburide tablet administered alone and with food.
Topics: Adolescent; Adult; Biological Availability; Cross-Over Studies; Female; Food-Drug Interactions; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Tablets | 2000 |
Effects of antihyperglycaemic therapies on proinsulin and relation between proinsulin and cardiovascular risk factors in type 2 diabetes.
Topics: Biomarkers; Blood Glucose; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet, Diabetic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Observer Variation; Proinsulin; Risk Factors; Triglycerides | 1999 |
Improved glycaemic control with miglitol in inadequately-controlled type 2 diabetics.
Topics: 1-Deoxynojirimycin; Analysis of Variance; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Drug Therapy, Combination; Female; Glucosamine; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Imino Pyranoses; Male; Metformin; Middle Aged; Placebos | 2001 |
Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia.
Topics: Aged; Aged, 80 and over; Blood Pressure; Brachial Artery; Diabetes Mellitus, Type 2; Diet, Diabetic; Female; Forearm; Gliclazide; Glyburide; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Ischemia; Male; Metformin; Middle Aged; Reference Values; Regional Blood Flow; Sulfonylurea Compounds; Ultrasonography | 2001 |
Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients.
Topics: Acetylcholine; Adult; Aged; Blood Flow Velocity; Blood Pressure; Body Mass Index; Body Weight; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Diazoxide; Dipyridamole; Double-Blind Method; Female; Forearm; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Sulfonylurea Compounds; Vasodilation | 2002 |
Differential effects of metformin and troglitazone on cardiovascular risk factors in patients with type 2 diabetes.
Topics: Blood Glucose; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Chromans; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipids; Lipoproteins, LDL; Male; Metformin; Middle Aged; Plasminogen Activator Inhibitor 1; Risk Factors; Thiazoles; Thiazolidinediones; Troglitazone | 2002 |
Simultaneous glyburide/metformin therapy is superior to component monotherapy as an initial pharmacological treatment for type 2 diabetes.
Topics: Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Placebos; Postprandial Period; Racial Groups; Safety; United States | 2002 |
Improved glycaemic control with metformin-glibenclamide combined tablet therapy (Glucovance) in Type 2 diabetic patients inadequately controlled on metformin.
Topics: Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Fructosamine; Gastrointestinal Diseases; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Tablets; Treatment Outcome | 2002 |
A diabetes outcome progression trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes.
Topics: Albuminuria; Blood Glucose; Diabetes Mellitus, Type 2; Disease Progression; Double-Blind Method; Glyburide; Humans; Hypoglycemic Agents; Metformin; Research Design; Rosiglitazone; Safety; Thiazoles; Thiazolidinediones; Time Factors; Treatment Failure; Treatment Outcome | 2002 |
Glyburide/metformin combination product is safe and efficacious in patients with type 2 diabetes failing sulphonylurea therapy.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Treatment Failure | 2002 |
Differential effect of glyburide (glibenclamide) and metformin on QT dispersion: a potential adenosine triphosphate sensitive K+ channel effect.
Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Diabetes Mellitus, Type 2; Electrocardiography; Glyburide; Glycated Hemoglobin; Heart Conduction System; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Treatment Outcome | 2002 |
Metformin plus glyburide combination as initial therapy in type 2 diabetes: one month follow-up.
Topics: Adult; Aged; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Drug Combinations; Exercise Therapy; Female; Follow-Up Studies; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged | 2002 |
Metformin plus glyburide combination as therapy in failure to monotherapy in type 2 diabetic patients: one month follow-up.
Topics: Adult; Aged; Blood Glucose; Combined Modality Therapy; Diabetes Mellitus, Type 2; Drug Combinations; Exercise Therapy; Female; Follow-Up Studies; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged | 2002 |
Beneficial effects of a glyburide/metformin combination preparation in type 2 diabetes mellitus.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Drug Combinations; Glyburide; Hemoglobin A; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin | 2003 |
Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Adult; Aged; Biopsy; Chromans; Culture Media, Conditioned; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Metformin; Middle Aged; Molecular Weight; Obesity; Proteins; Thiazoles; Thiazolidinediones; Tissue Distribution; Troglitazone | 2003 |
Leptin and body fat in type 2 diabetes and monodrug therapy.
Topics: Adipose Tissue; Body Composition; Body Mass Index; Cholesterol, HDL; Cross-Over Studies; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Leptin; Male; Metformin; Middle Aged | 2003 |
Effect of metformin and sulfonylurea on C-reactive protein level in well-controlled type 2 diabetics with metabolic syndrome.
Topics: Blood Glucose; Body Mass Index; C-Reactive Protein; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hyperlipidemias; Hypertension; Hypoglycemic Agents; Male; Metabolic Syndrome; Metformin; Middle Aged; Sex Characteristics; Sulfonylurea Compounds | 2003 |
Elevated concentrations of C-reactive protein in subjects with type 2 diabetes mellitus are moderately influenced by glycemic control.
Topics: Adult; Aged; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Lipids; Male; Metformin; Middle Aged; Osmolar Concentration | 2003 |
Combination treatment with metformin and glibenclamide versus single-drug therapies in type 2 diabetes mellitus: a randomized, double-blind, comparative study.
Topics: Blood Glucose; Body Mass Index; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Fasting; Female; Glyburide; Glycated Hemoglobin; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Islets of Langerhans; Male; Metformin; Middle Aged | 2003 |
Efficacy of glyburide/metformin tablets compared with initial monotherapy in type 2 diabetes.
Topics: Adult; Aged; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Fructosamine; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Postprandial Period | 2003 |
Comparative bioavailability of two oral formulations manufactured in Mexico containing glyburide and metformin in diabetic patients.
Topics: Aged; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Half-Life; Humans; Hypoglycemic Agents; Metformin; Mexico; Spectrophotometry, Ultraviolet; Tablets | 2003 |
Glycemic control with glyburide/metformin tablets in combination with rosiglitazone in patients with type 2 diabetes: a randomized, double-blind trial.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Rosiglitazone; Thiazolidinediones | 2004 |
Beneficial effects of addition of oral spray insulin (Oralin) on insulin secretion and metabolic control in subjects with type 2 diabetes mellitus suboptimally controlled on oral hypoglycemic agents.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Metformin; Middle Aged; Prospective Studies; Statistics, Nonparametric | 2004 |
Durable efficacy of metformin/glibenclamide combination tablets (Glucovance) during 52 weeks of open-label treatment in type 2 diabetic patients with hyperglycaemia despite previous sulphonylurea monotherapy.
Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Tablets; Treatment Outcome | 2004 |
Adiponectin and C-reactive protein in obesity, type 2 diabetes, and monodrug therapy.
Topics: Adiponectin; Blood Glucose; Body Composition; C-Reactive Protein; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Leptin; Linear Models; Lipids; Male; Metformin; Middle Aged; Obesity; Sex Factors | 2004 |
Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes.
Topics: Carotid Arteries; Carotid Artery Diseases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Follow-Up Studies; Gliclazide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Multivariate Analysis; Tunica Intima; Tunica Media | 2004 |
Effects of two different glibenclamide dose-strengths in the fixed combination with metformin in patients with poorly controlled T2DM: a double blind, prospective, randomised, cross-over clinical trial.
Topics: Adult; Blood Glucose; Body Mass Index; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Fasting; Female; Food; Glyburide; Glycated Hemoglobin; History, 18th Century; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Middle Aged; Prospective Studies | 2004 |
Investigation of the pharmacokinetic and pharmacodynamic interactions between memantine and glyburide/metformin in healthy young subjects: a single-center, multiple-dose, open-label study.
Topics: Adult; Alzheimer Disease; Diabetes Mellitus, Type 2; Drug Combinations; Drug Interactions; Female; Glyburide; Humans; Male; Memantine; Metformin | 2005 |
Biphasic insulin aspart 30 plus metformin: an effective combination in type 2 diabetes.
Topics: Biphasic Insulins; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Aspart; Insulin, Isophane; Male; Metformin; Middle Aged; Treatment Outcome | 2006 |
Improving metabolic control leads to better working memory in adults with type 2 diabetes.
Topics: Adult; Aged; Blood Glucose; Cognition; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Memory; Metformin; Middle Aged; Psychological Tests; Rosiglitazone; Stress, Psychological; Thiazolidinediones | 2006 |
Metformin-glibenclamide versus metformin plus rosiglitazone in patients with type 2 diabetes inadequately controlled on metformin monotherapy.
Topics: Adult; Aged; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Lipid Metabolism; Male; Metformin; Middle Aged; Rosiglitazone; Tablets; Thiazolidinediones; Treatment Outcome | 2006 |
The Pro12Ala variant of the PPARG gene is a risk factor for peroxisome proliferator-activated receptor-gamma/alpha agonist-induced edema in type 2 diabetic patients.
Topics: Diabetes Mellitus, Type 2; DNA; Edema; Female; Genetic Predisposition to Disease; Genotype; Glyburide; Haplotypes; Humans; Hypoglycemic Agents; Logistic Models; Male; Metformin; Oxazines; Phenylpropionates; Polymorphism, Single Nucleotide; PPAR alpha; PPAR gamma; Proportional Hazards Models | 2006 |
Beta-cell response to metformin-glibenclamide combination tablets (Glucovance) in patients with type 2 diabetes.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Glucose Tolerance Test; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Tablets; Treatment Outcome | 2006 |
Glycemic control and treatment failure with pioglitazone versus glibenclamide in type 2 diabetes mellitus: a 42-month, open-label, observational, primary care study.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Pioglitazone; Primary Health Care; Prospective Studies; Thiazolidinediones; Treatment Outcome | 2006 |
An open, randomized, parallel-group study to compare the efficacy and safety profile of inhaled human insulin (Exubera) with glibenclamide as adjunctive therapy in patients with type 2 diabetes poorly controlled on metformin.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Insulin; Male; Metformin; Middle Aged; Treatment Outcome | 2006 |
Glycaemic and nonglycaemic effects of pioglitazone in triple oral therapy of patients with type 2 diabetes.
Topics: Adiponectin; Administration, Oral; Aged; Biomarkers; Blood Glucose; Case-Control Studies; Cystatin C; Cystatins; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Pioglitazone; Proinsulin; Prospective Studies; Statistics, Nonparametric; Thiazolidinediones | 2006 |
Rosiglitazone reduces microalbuminuria and blood pressure independently of glycemia in type 2 diabetes patients with microalbuminuria.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Blood Pressure; Cohort Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Rosiglitazone; Thiazolidinediones | 2006 |
A Diabetes Outcome Progression Trial (ADOPT): baseline characteristics of Type 2 diabetic patients in North America and Europe.
Topics: Adult; Age Distribution; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Europe; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Metabolic Syndrome; Metformin; Middle Aged; North America; Racial Groups; Rosiglitazone; Sex Distribution; Thiazolidinediones | 2006 |
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.
Topics: Cardiovascular Diseases; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Kaplan-Meier Estimate; Male; Metformin; Middle Aged; Proportional Hazards Models; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Waist-Hip Ratio; Weight Gain | 2006 |
Lowering effect on postprandial glycemic response of nopales added to Mexican breakfasts.
Topics: Aged; Blood Glucose; Cactaceae; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Eating; Glyburide; Humans; Hypoglycemic Agents; Metformin; Mexico; Middle Aged; Phytotherapy; Plant Extracts; Postprandial Period | 2007 |
[ADOPT study: which first-line glucose-lowering oral medication in type 2 diabetes?].
Topics: Administration, Oral; Belgium; Canada; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Double-Blind Method; European Union; Glyburide; Humans; Hypoglycemic Agents; Metformin; Middle Aged; Quality of Life; Rosiglitazone; Thiazolidinediones; Treatment Outcome; United States | 2007 |
Simultaneous assay of metformin and glibenclamide in human plasma based on extraction-less sample preparation procedure and LC/(APCI)MS.
Topics: Adult; Chromatography, Liquid; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Mass Spectrometry; Metformin; Sensitivity and Specificity; Therapeutic Equivalency | 2007 |
Comparison of extended-release metformin in combination with a sulfonylurea (glyburide) to sulfonylurea monotherapy in adult patients with type 2 diabetes: a multicenter, double-blind, randomized, controlled, phase III study.
Topics: Adolescent; Adult; Aged; Body Mass Index; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged | 2007 |
Effects of pioglitazone in combination with metformin or a sulfonylurea compared to a fixed-dose combination of metformin and glibenclamide in patients with type 2 diabetes.
Topics: Adult; C-Peptide; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Metformin; Pioglitazone; Safety; Thiazolidinediones | 2007 |
The effect of pioglitazone as add-on therapy to metformin or sulphonylurea compared to a fixed-dose combination of metformin and glibenclamide on diabetic dyslipidaemia.
Topics: Aged; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Combinations; Drug Therapy, Combination; Dyslipidemias; Female; Glyburide; Humans; Hypoglycemic Agents; Italy; Male; Metformin; Middle Aged; Pioglitazone; Sulfonylurea Compounds; Thiazolidinediones; Treatment Outcome; Triglycerides | 2008 |
Nateglinide, alone or in combination with metformin, is effective and well tolerated in treatment-naïve elderly patients with type 2 diabetes.
Topics: Aged; Aged, 80 and over; Blood Glucose; Body Mass Index; Cyclohexanes; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nateglinide; Phenylalanine; Treatment Outcome | 2008 |
Effects of nateglinide and glibenclamide on prothrombotic factors in naïve type 2 diabetic patients treated with metformin: a 1-year, double-blind, randomized clinical trial.
Topics: Adult; Cyclohexanes; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nateglinide; Phenylalanine; Plasminogen Activator Inhibitor 1; Tissue Plasminogen Activator | 2007 |
Rosiglitazone improves endothelial function and inflammation but not asymmetric dimethylarginine or oxidative stress in patients with type 2 diabetes mellitus.
Topics: Adult; Aged; Arginine; Biomarkers; Blood Glucose; Blood Pressure; Brachial Artery; C-Reactive Protein; Carotid Arteries; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Elasticity; Endothelium, Vascular; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Insulin; Male; Metformin; Middle Aged; Oxidative Stress; Rosiglitazone; Thiazolidinediones; Treatment Outcome; Vasodilation | 2007 |
Effect of glyburide-metformin combination tablet in patients with type 2 diabetes.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Patient Compliance | 2007 |
Increased hematocrit and reduced blood pressure following control of glycemia in diabetes.
Topics: Blood Glucose; Blood Pressure; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Hematocrit; Humans; Male; Metformin; Salvage Therapy; Weight Loss | 2008 |
Rosiglitazone-associated fractures in type 2 diabetes: an Analysis from A Diabetes Outcome Progression Trial (ADOPT).
Topics: Age of Onset; Aged; Diabetes Mellitus, Type 2; Disease Progression; Female; Fractures, Bone; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Rosiglitazone; Thiazolidinediones; Treatment Outcome | 2008 |
Cardiovascular, metabolic and hormonal responses to the progressive exercise performed to exhaustion in patients with type 2 diabetes treated with metformin or glyburide.
Topics: Blood Glucose; Cardiovascular Physiological Phenomena; Case-Control Studies; Diabetes Mellitus, Type 2; Exercise; Exercise Tolerance; Fatigue; Female; Glyburide; Hormones; Humans; Hypoglycemic Agents; Metformin; Middle Aged | 2008 |
Comparison of glycaemic control in patients with Type 2 diabetes on basal insulin and fixed combination oral antidiabetic treatment: results of a pilot study.
Topics: Administration, Oral; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin, Isophane; Insulin, Long-Acting; Male; Metformin; Middle Aged; Monitoring, Ambulatory; Pilot Projects | 2009 |
Nateglinide and glibenclamide metabolic effects in naïve type 2 diabetic patients treated with metformin.
Topics: Blood Glucose; Body Mass Index; Cyclohexanes; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Hemodynamics; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Lipids; Male; Metformin; Middle Aged; Nateglinide; Phenylalanine | 2009 |
Effect of two starting insulin regimens in patients with type II diabetes not controlled on a combination of oral antihyperglycemic medications.
Topics: Animals; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Lispro; Male; Metformin; Middle Aged; Patient Selection; Postprandial Period | 2009 |
Insulin-based versus triple oral therapy for newly diagnosed type 2 diabetes: which is better?
Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones; Treatment Outcome; Young Adult | 2009 |
Rosiglitazone decreases C-reactive protein to a greater extent relative to glyburide and metformin over 4 years despite greater weight gain: observations from a Diabetes Outcome Progression Trial (ADOPT).
Topics: Adult; Aged; C-Reactive Protein; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Rosiglitazone; Thiazolidinediones; Time; Treatment Outcome; Weight Gain | 2010 |
Effect of rosiglitazone, metformin, and glyburide on bone biomarkers in patients with type 2 diabetes.
Topics: Adult; Aged; Biomarkers; Bone and Bones; Bone Resorption; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Osteogenesis; Rosiglitazone; Thiazolidinediones | 2010 |
Metformin compared with glyburide in gestational diabetes: a randomized controlled trial.
Topics: Adult; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Metformin; Pregnancy; Pregnancy Outcome; Treatment Outcome; Young Adult | 2010 |
Exenatide versus glibenclamide in patients with diabetes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Body Mass Index; Body Weight; C-Reactive Protein; Diabetes Mellitus, Type 2; Exenatide; Female; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Incretins; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Peptides; Proinsulin; Resistin; Retinol-Binding Proteins, Plasma; Venoms; Young Adult | 2010 |
Metformin compared with glyburide for the management of gestational diabetes.
Topics: Birth Weight; Blood Glucose; Diabetes, Gestational; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy; Treatment Outcome | 2010 |
Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects.
Topics: Adamantane; Adolescent; Adult; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones; Young Adult | 2011 |
Effects of rosiglitazone, glyburide, and metformin on β-cell function and insulin sensitivity in ADOPT.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Rosiglitazone; Thiazolidinediones | 2011 |
Renal function in type 2 diabetes with rosiglitazone, metformin, and glyburide monotherapy.
Topics: Adult; Aged; Albuminuria; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Follow-Up Studies; Glomerular Filtration Rate; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Kidney; Male; Metformin; Middle Aged; Rosiglitazone; Thiazolidinediones; Treatment Outcome | 2011 |
Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes.
Topics: Adamantane; Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Thiazolidinediones; United States; Young Adult | 2011 |
Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; E-Selectin; F2-Isoprostanes; Female; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Incretins; Insulin; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Metformin; Middle Aged; Oxidative Stress; Piperidines; Postprandial Period; Time Factors; Treatment Outcome; Wales | 2011 |
Effects of acarbose versus glibenclamide on glycemic excursion and oxidative stress in type 2 diabetic patients inadequately controlled by metformin: a 24-week, randomized, open-label, parallel-group comparison.
Topics: Acarbose; Adult; Aged; Biomarkers; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dinoprost; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Lipids; Lipoproteins, LDL; Male; Medication Adherence; Metformin; Middle Aged; Outpatients; Oxidative Stress; Regression Analysis; Taiwan; Time Factors; Treatment Outcome | 2011 |
Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial.
Topics: Adult; Aloe; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Gels; Glyburide; Humans; Hypercholesterolemia; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Male; Metformin; Middle Aged; Phytotherapy; Placebos; Plant Extracts; Plant Leaves | 2012 |
Perinatal impact of the use of metformin and glyburide for the treatment of gestational diabetes mellitus.
Topics: Adult; Birth Weight; Blood Glucose; Diabetes, Gestational; Female; Glucose Tolerance Test; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Male; Metformin; Pregnancy; Pregnancy Outcome; Weight Gain | 2012 |
The effect of sitagliptin versus glibenclamide on arterial stiffness, blood pressure, lipids, and inflammation in type 2 diabetes mellitus patients.
Topics: Adolescent; Adult; Aged; Blood Glucose; Blood Pressure; C-Reactive Protein; Cross-Over Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipids; Male; Metformin; Middle Aged; Prospective Studies; Pyrazines; Sitagliptin Phosphate; Triazoles; Vascular Stiffness; Young Adult | 2012 |
β-cell function preservation after 3.5 years of intensive diabetes therapy.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Patient Compliance; Pioglitazone; Thiazolidinediones | 2012 |
Effect of insulin versus triple oral therapy on the progression of hepatic steatosis in type 2 diabetes.
Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Disease Progression; Fatty Liver; Female; Follow-Up Studies; Glyburide; Humans; Hypoglycemic Agents; Insulin; Liver; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones; Triglycerides; Young Adult | 2012 |
Lack of the QTc physiologic decrease during cardiac stress test in patients with type 2 diabetes treated with secretagogues.
Topics: Aged; Arrhythmias, Cardiac; Carbamates; Diabetes Mellitus, Type 2; Electrocardiography; Exercise Test; Female; Glyburide; Heart Rate; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Piperidines | 2014 |
A comparison between sitagliptin or glibenclamide in addition to metformin + pioglitazone on glycaemic control and β-cell function: the triple oral therapy.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Fasting; Female; Glucose Clamp Technique; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Pioglitazone; Pyrazines; Sitagliptin Phosphate; Thiazolidinediones; Triazoles | 2013 |
A randomized, double-blind, comparative therapy evaluating sitagliptin versus glibenclamide in type 2 diabetes patients already treated with pioglitazone and metformin: a 3-year study.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Metformin; Obesity; Pioglitazone; Pyrazines; Sitagliptin Phosphate; Thiazolidinediones; Treatment Outcome; Triazoles | 2013 |
Ultrasonography modifications of visceral and subcutaneous adipose tissue after pioglitazone or glibenclamide therapy combined with rosuvastatin in type 2 diabetic patients not well controlled by metformin.
Topics: Adipokines; Aged; Biomarkers; Blood Glucose; Body Mass Index; Body Weight; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Fatty Liver; Female; Fluorobenzenes; Glucose Clamp Technique; Glyburide; Humans; Hypoglycemic Agents; Inflammation Mediators; Insulin; Intra-Abdominal Fat; Italy; Lipids; Male; Metformin; Middle Aged; Pioglitazone; Pyrimidines; Rosuvastatin Calcium; Subcutaneous Fat; Sulfonamides; Thiazolidinediones; Time Factors; Treatment Outcome; Ultrasonography | 2013 |
Tolerability and efficacy of glycemic control with saxagliptin in older patients (aged ≥ 65 years) with inadequately controlled type 2 diabetes mellitus.
Topics: Adamantane; Aged; Aged, 80 and over; Analysis of Variance; Area Under Curve; Diabetes Mellitus, Type 2; Dipeptides; Double-Blind Method; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Incretins; Male; Metformin; Thiazolidinediones; Treatment Outcome | 2013 |
Saxagliptin efficacy and safety in patients with type 2 diabetes mellitus and cardiovascular disease history or cardiovascular risk factors: results of a pooled analysis of phase 3 clinical trials.
Topics: Adamantane; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dipeptides; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Metformin; Risk Factors; Thiazolidinediones | 2013 |
Pharmacokinetic studies of metformin and glibenclamide in normal human volunteers.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Stability; Glyburide; Humans; Hypoglycemic Agents; Male; Metabolic Clearance Rate; Metformin; Middle Aged | 2014 |
Effects of Juglans regia L. leaf extract on hyperglycemia and lipid profiles in type two diabetic patients: a randomized double-blind, placebo-controlled clinical trial.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Iran; Juglans; Lipids; Male; Metformin; Middle Aged; Plant Extracts; Plant Leaves | 2014 |
Comparison of neonatal outcomes in women with gestational diabetes with moderate hyperglycaemia on metformin or glibenclamide--a randomised controlled trial.
Topics: Adult; Birth Injuries; Birth Weight; Diabetes, Gestational; Female; Fetal Macrosomia; Glyburide; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Infant, Newborn; Jaundice, Neonatal; Labor, Induced; Metformin; Obstetric Labor Complications; Perinatal Death; Pregnancy; Premature Birth; Respiratory Distress Syndrome, Newborn; Single-Blind Method; Stillbirth | 2015 |
Glycemic excursions are positively associated with changes in duration of asymptomatic hypoglycemia after treatment intensification in patients with type 2 diabetes.
Topics: Acarbose; Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Monitoring, Ambulatory | 2016 |
Glycemic excursions are positively associated with HbA1c reduction from baseline after treatment with acarbose in patients with type 2 diabetes on metformin monotherapy.
Topics: Acarbose; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Linear Models; Male; Metformin; Middle Aged; Treatment Outcome | 2017 |
Pharmacokinetic and Pharmacodynamic Drug Interaction Study of Piragliatin, a Glucokinase Activator, and Glyburide, a Sulfonylurea, in Type 2 Diabetic Patients.
Topics: Adult; Aged; Benzeneacetamides; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Endpoint Determination; Enzyme Activators; Female; Glucokinase; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Sitagliptin Phosphate | 2016 |
Glyburide Versus Metformin and Their Combination for the Treatment of Gestational Diabetes Mellitus: A Randomized Controlled Study.
Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Diabetes, Gestational; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Israel; Metformin; Middle Aged; Pregnancy; Prospective Studies; Sample Size; Treatment Failure; Treatment Outcome; Young Adult | 2017 |
Effects of Type 2 Diabetes Mellitus in Patients on Treatment With Glibenclamide and Metformin on Carvedilol Enantiomers Metabolism.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Area Under Curve; Carbazoles; Carvedilol; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Hand Strength; Heart Rate; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Propanolamines; Stereoisomerism | 2017 |
Glibenclamide and metfoRmin versus stAndard care in gEstational diabeteS (GRACES): a feasibility open label randomised trial.
Topics: Adult; Blood Glucose; Diabetes, Gestational; Drug Therapy, Combination; Feasibility Studies; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Medication Adherence; Metformin; Patient Selection; Pregnancy | 2017 |
SUGAR-DIP trial: oral medication strategy versus insulin for diabetes in pregnancy, study protocol for a multicentre, open-label, non-inferiority, randomised controlled trial.
Topics: Administration, Oral; Blood Glucose; Cost-Benefit Analysis; Diabetes, Gestational; Drug Therapy, Combination; Equivalence Trials as Topic; Female; Gestational Age; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Multicenter Studies as Topic; Pregnancy; Pregnancy Outcome | 2019 |
Pharmacodynamics of Glyburide, Metformin, and Glyburide/Metformin Combination Therapy in the Treatment of Gestational Diabetes Mellitus.
Topics: Adolescent; Adult; Blood Glucose; Diabetes, Gestational; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Longitudinal Studies; Metformin; Pregnancy; Prospective Studies; Young Adult | 2020 |
Bioequivalence and pharmacokinetic comparison of two fixed dose combination of Metformin/ Glibenclamide formulations in healthy subjects under fed condition.
Topics: Adolescent; Adult; Cross-Over Studies; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Therapeutic Equivalency; Young Adult | 2020 |
Dapagliflozin effect on endothelial dysfunction in diabetic patients with atherosclerotic disease: a randomized active-controlled trial.
Topics: Adult; Aged; Benzhydryl Compounds; Biomarkers; Blood Glucose; Brazil; Carotid Artery Diseases; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Endothelium, Vascular; Female; Glucosides; Glyburide; Glycated Hemoglobin; Humans; Male; Metformin; Middle Aged; Prospective Studies; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome; Vasodilation | 2021 |
Dapagliflozin increases the lean-to total mass ratio in type 2 diabetes mellitus.
Topics: Absorptiometry, Photon; Adult; Aged; Benzhydryl Compounds; Blood Glucose; Body Composition; Body Weight; Carotid Artery Diseases; Diabetes Mellitus, Type 2; Female; Glucosides; Glyburide; Glycated Hemoglobin; Hand Strength; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Treatment Outcome | 2021 |
Pharmacokinetic and Bioequivalence Studies of 2 Metformin Glibenclamide Tablets in Healthy Chinese Subjects Under Fasting and Fed Conditions.
Topics: Cross-Over Studies; Diabetes Mellitus, Type 2; East Asian People; Fasting; Glyburide; Humans; Metformin; Tablets; Therapeutic Equivalency | 2023 |
243 other study(ies) available for glyburide and metformin
| Article | Year |
|---|---|
Antihyperglycemic activity of novel naphthalenyl 3H-1,2,3,5-oxathiadiazole 2-oxides.
Topics: Animals; Blood Glucose; Female; Hypoglycemic Agents; Male; Mice; Mice, Obese; Naphthalenes; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiadiazoles | 1993 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Novel substituted naphthalen-1-yl-methanone derivatives as anti-hyperglycemic agents.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Naphthalenes; Rats; Rats, Sprague-Dawley; Streptozocin | 2006 |
Chalcone based aryloxypropanolamines as potential antihyperglycemic agents.
Topics: Animals; Chalones; Diabetes Mellitus, Experimental; Hyperglycemia; Hypoglycemic Agents; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-3; Sucrose | 2007 |
Synthesis and antihyperglycemic activity of novel N-acyl-2-arylethylamines and N-acyl-3-coumarylamines.
Topics: Acylation; Animals; Blood Glucose; Coumaric Acids; Diabetes Mellitus, Experimental; Ethylamines; Hyperglycemia; Hypoglycemic Agents; Male; Models, Chemical; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Novel 2-aryl-naphtho[1,2-d]oxazole derivatives as potential PTP-1B inhibitors showing antihyperglycemic activities.
Topics: Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Hypoglycemic Agents; Lipids; Mice; Oxazoles; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Structure-Activity Relationship; Triglycerides | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents.
Topics: Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Hypoglycemic Agents; Hypolipidemic Agents; Isoxazoles; Male; Mice; Mice, Inbred C57BL; PPAR gamma; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Rats, Sprague-Dawley; Rats, Wistar; Streptozocin; Sucrose; Triglycerides | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Design and synthesis of 2,4-disubstituted polyhydroquinolines as prospective antihyperglycemic and lipid modulating agents.
Topics: Animals; Diabetes Mellitus, Experimental; Drug Design; Dyslipidemias; Glycogen Phosphorylase; Hypoglycemic Agents; Mice; Mice, Inbred Strains; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Quinolines | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Hypoglycemic diterpenoids from Tinospora crispa.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diterpenes; Hypoglycemic Agents; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Streptozocin; Tinospora | 2012 |
Synthesis of propiophenone derivatives as new class of antidiabetic agents reducing body weight in db/db mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Eating; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Male; Mice; Mice, Inbred C57BL; Propiophenones; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Rats, Sprague-Dawley; Rats, Wistar; Streptozocin; Weight Loss | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Identification of small molecules that bind to the mitochondrial protein mitoNEET.
Topics: Hypoglycemic Agents; Ligands; Mitochondrial Proteins; Protein Binding; Small Molecule Libraries; Thiazolidinediones | 2016 |
New insights into the biological activities of Chrysanthemum morifolium: Natural flavonoids alleviate diabetes by targeting α-glucosidase and the PTP-1B signaling pathway.
Topics: Animals; Cell Line, Tumor; Cholesterol; Chrysanthemum; Cricetulus; Diabetes Mellitus, Experimental; Flavonoids; Glucose; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Male; Mice; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Signal Transduction; Streptozocin; Triglycerides | 2019 |
Diabetes newly diagnosed during pregnancy: A 4-year study at Groote Schuur Hospital.
Topics: Adolescent; Adult; Birth Weight; Black or African American; Black People; Delivery, Obstetric; Diabetes Mellitus; Female; Glucagon; Glucose Tolerance Test; Glyburide; Humans; Infant Mortality; Insulin; Ketones; Labor, Obstetric; Metformin; Pregnancy; Pregnancy in Diabetics; South Africa; White People | 1979 |
Side effects of therapy in diabetes evaluated by a self-administered questionnaire.
Topics: Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Patient Acceptance of Health Care; Phenformin; Surveys and Questionnaires; Tolbutamide | 1977 |
Comparative effects of phenformin, metformin and glibenclamide on metabolic rhythms in maturity-onset diabetics.
Topics: Aged; Alanine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus; Female; Gluconeogenesis; Glyburide; Humans; Insulin; Ketone Bodies; Lactates; Lipids; Male; Metformin; Middle Aged; Phenformin; Pyruvates | 1977 |
[Clinico-statistical studies of the use of oral hypoglycemic agents in the therapy of diabetes: critical evaluation of their effectiveness and tolerance].
Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus; Drug Evaluation; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Phenformin; Tolbutamide | 1977 |
Myocardial infarction in diabetics.
Topics: Administration, Oral; Adult; Aged; Chlorpropamide; Coronary Care Units; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Myocardial Infarction; Phenformin; Sex Factors; Sulfonylurea Compounds; Tolbutamide | 1975 |
Effect of bed time intermediate acting insulin in NIDDM subjects refractory to a combination of sulphonylureas and biguanides.
Topics: Biguanides; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Drug Combinations; Female; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Injections, Subcutaneous; Insulin, Long-Acting; Lipids; Male; Metformin; Middle Aged; Phenformin; Sulfonylurea Compounds; Time Factors | 1992 |
[Median-term (4 months) treatment with glibenclamide + metformin substituting for glibenclamide + fenformin lowers the lacticemia levels in type-2 diabetics (NIDDM)].
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Glyburide; Glycated Hemoglobin; Glycosuria; Humans; Lactates; Lactic Acid; Male; Metformin; Middle Aged; Phenformin | 1992 |
Relationship between blood pressure and in vivo action of insulin in type II (non-insulin-dependent) diabetic subjects.
Topics: Antihypertensive Agents; Blood Pressure; C-Peptide; Diabetes Mellitus, Type 2; Diet, Diabetic; Female; Glucagon; Glucose Clamp Technique; Glyburide; Glycated Hemoglobin; Humans; Hypertension; Infusions, Intravenous; Insulin; Male; Metformin; Middle Aged; Regression Analysis | 1992 |
Co-secretion of amylin and insulin from cultured islet beta-cells: modulation by nutrient secretagogues, islet hormones and hypoglycemic agents.
Topics: Amyloid; Animals; Arginine; Cell Line; Cricetinae; Glucagon; Glucose; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Kinetics; Metformin; Somatostatin; Tolbutamide | 1991 |
Counteraction of nifedipine-induced hyperglycaemia by metformin.
Topics: Animals; Glyburide; Hyperglycemia; Male; Metformin; Nifedipine; Rats | 1990 |
[Sulfonylurea compounds or biguanides in the treatment of type 2 diabetes?].
Topics: Aged; Animals; Biguanides; Cricetinae; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Humans; Metformin; Rats; Sulfonylurea Compounds | 1989 |
Interaction between diazepam and oral antidiabetic agents on serum glucose, insulin and chromium levels in rats.
Topics: Animals; Blood Glucose; Chromium; Diazepam; Drug Interactions; Glyburide; Hypoglycemic Agents; Insulin; Male; Metformin; Rats; Rats, Inbred Strains | 1989 |
Platelet and endothelial function tests during metformin treatment in diabetes mellitus (short communication).
Topics: 6-Ketoprostaglandin F1 alpha; Aged; Antigens; beta-Thromboglobulin; Blood Platelets; Diabetes Mellitus, Type 2; Endothelium; Factor VIII; Female; Glyburide; Humans; Male; Metformin; Middle Aged; Platelet Aggregation; Thromboxane B2; von Willebrand Factor | 1985 |
[Secondary failure of oral antidiabetics. Value of intravenous insulin infusions].
Topics: Administration, Oral; Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Infusion Systems; Male; Metformin; Middle Aged | 1986 |
Effects of metformin and glibenclamide on insulin receptors in fibroblasts and tumor cells in vitro.
Topics: Breast Neoplasms; Colonic Neoplasms; Fibroblasts; Glyburide; Humans; In Vitro Techniques; Insulin; Metformin; Receptor, Insulin; Tumor Cells, Cultured | 1987 |
Metformin and the sulphonylureas: the comparative risk.
Topics: Acidosis; Diabetes Mellitus, Type 2; Drug Interactions; Glyburide; Humans; Hypoglycemia; Metformin; Risk; Sulfonylurea Compounds | 1985 |
Mild familial diabetes with dominant inheritance.
Topics: Acetohexamide; Adolescent; Adult; Aged; Blood Glucose; Carbohydrates; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diet Therapy; Female; Genes, Dominant; Glucose Tolerance Test; Glyburide; Glycosuria; Humans; Insulin; Insulin Secretion; Ketone Bodies; Male; Metformin; Middle Aged; Pregnancy; Pregnancy in Diabetics; Radioimmunoassay; Sulfonylurea Compounds | 1974 |
[Oral antidiabetic therapy with delayed-action glibenclamide and phenformin in fixed combination].
Topics: Adult; Aged; Blood Glucose; Carbutamide; Cholesterol; Delayed-Action Preparations; Diabetes Mellitus; Drug Combinations; Evaluation Studies as Topic; Fatty Acids, Nonesterified; Female; Glyburide; Glycosuria; Humans; Lipids; Male; Metformin; Middle Aged; Phenformin; Tolbutamide; Triglycerides | 1974 |
[Glibenclamide, a new oral antidiabetic].
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; Glyburide; Humans; Insulin; Male; Metformin; Middle Aged; Phenformin; Sulfonylurea Compounds | 1972 |
Oral therapy in diabetes.
Topics: Acetohexamide; Administration, Oral; Animals; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Evaluation Studies as Topic; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Obesity; Phenformin; Pyrimidines; Sulfonamides; Time Factors; Tolbutamide | 1972 |
The effect of biguanides on secretion and biosynthesis of insulin in isolated pancreatic islets of rats.
Topics: Animals; Biguanides; Drug Interactions; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Metformin; Oxygen Consumption; Phenformin; Rats; Rats, Inbred Strains; Tritium | 1972 |
Clinical observations on the mechanism of the antidiuretic action of chlorpropamide in vasopressin-sensitive diabetes insipidus and in normal subjects.
Topics: Adolescent; Adult; Blood Glucose; Child; Child, Preschool; Chlorpropamide; Diabetes Insipidus; Drug Synergism; Ethanol; Glyburide; Humans; Hypoglycemia; Metformin; Middle Aged; Osmolar Concentration; Sodium; Thiazines; Vasopressins; Water | 1972 |
[Diabetes mellitus].
Topics: Adult; Blood Glucose; Diabetes Mellitus; Glyburide; Humans; Insulin; Metformin | 1983 |
[Hypoglycemic effects of the blended Chinese traditional medicines in genetically and chemically diabetic mice].
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic Agents; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Metformin; Mice; Tolbutamide | 1984 |
Metformin and glibenclamide: comparative risks.
Topics: Acidosis; Aged; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemia; Lactates; Metformin; Risk | 1984 |
Lack of effect of glibenclamide, chlorpropamide and metformin on plasma cholesterol and HDL-cholesterol in non-diabetic rats.
Topics: Animals; Chlorpropamide; Cholesterol; Glyburide; Lipoproteins, HDL; Male; Metformin; Rats | 1980 |
Pregnancy in established non-insulin-dependent diabetics. A five-and-a-half year study at Groote Schuur Hospital.
Topics: Diabetes Mellitus; Female; Glyburide; Humans; Infant Mortality; Insulin; Labor, Induced; Metformin; Pregnancy; Pregnancy in Diabetics | 1980 |
Chronic effects of glibenclamide, chlorpropamide and metformin on plasma glucose and insulin in non-diabetic rats.
Topics: Animals; Blood Glucose; Chlorpropamide; Glucose Tolerance Test; Glyburide; Insulin; Male; Metformin; Rats; Rats, Inbred Strains; Time Factors | 1981 |
Plasma high density lipoprotein cholesterol in streptozotocin diabetic and non-diabetic mice after prolonged administration of glibenclamide, chlorpropamide and metformin.
Topics: Animals; Blood Glucose; Body Weight; Chlorpropamide; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Experimental; Glyburide; Kinetics; Lipoproteins, HDL; Male; Metformin; Mice | 1981 |
Pemphigus vulgaris precipitated by glibenclamide therapy.
Topics: Aged; Azathioprine; Candidiasis, Oral; Diabetes Mellitus, Type 2; Drug Hypersensitivity; Fluconazole; Glyburide; Humans; Hyperglycemia; Male; Metformin; Pemphigus; Prednisolone | 1993 |
Studies on pyrazinoylguanidine. 2. Comparative drug and dose effects on glucose and lipid metabolism in streptozotocin-induced diabetic rats.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glyburide; Guanidines; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Metabolism; Male; Metformin; Pyrazinamide; Pyrazines; Rats; Rats, Sprague-Dawley; Streptozocin | 1996 |
Differential inhibitory effects of antidiabetic drugs on arterial smooth muscle cell proliferation.
Topics: Animals; Aorta, Thoracic; Cattle; Cell Division; Cells, Cultured; Fetal Blood; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Metformin; Muscle, Smooth, Vascular; Pioglitazone; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidinediones | 1996 |
[Comparison of two treatment models in type-II diabetic patients with poor metabolic control: Preformed combination of glibenclamide 2,5 mg + metformin 400 mg or mono-therapy with sulfonylurea at maximal doses? An evaluation at six months].
Topics: Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Combinations; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Treatment Outcome | 1996 |
Effects of glibenclamide and metformin (alone or in combination) on insulin release from isolated human pancreatic islets.
Topics: Cell Separation; Centrifugation, Density Gradient; Collagenases; Glyburide; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Metformin | 1997 |
Disparate effects of antidiabetic drugs on arterial contraction.
Topics: Animals; Arteries; Blood Pressure; Glyburide; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Male; Metformin; Muscle Contraction; Muscle, Smooth, Vascular; Pioglitazone; Potassium Chloride; Rats; Rats, Wistar; Tail; Thiazoles; Thiazolidinediones | 1997 |
A retrospective analysis of the efficacy and safety of metformin in the African-American patient.
Topics: Adult; Aged; Aged, 80 and over; Black People; Body Weight; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin, Isophane; Male; Metformin; Middle Aged; Prognosis; Retrospective Studies | 1997 |
Action of metformin on erythrocyte membrane fluidity in vitro and in vivo.
Topics: Adult; Diabetes Mellitus, Type 2; Erythrocyte Membrane; Fluorescent Dyes; Glyburide; Humans; Hypoglycemic Agents; In Vitro Techniques; Male; Membrane Fluidity; Metformin | 1997 |
Effects of glycosylation of hypoglycaemic drug binding to serum albumin.
Topics: Acetohexamide; Binding Sites; Binding, Competitive; Gliclazide; Glyburide; Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Humans; Hypoglycemic Agents; Metformin; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Tolbutamide | 1997 |
Lactic acidosis with therapeutic metformin blood level in a low-risk diabetic patient.
Topics: Acidosis, Lactic; Adult; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Lisinopril; Metformin | 1998 |
Chorea in hyperglycemia.
Topics: Aged; Aged, 80 and over; Brain; Chorea; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburide; Humans; Hyperglycemia; Hypertension; Hypoglycemic Agents; Magnetic Resonance Imaging; Metformin | 1998 |
The biguanide compound metformin prevents desensitization of human pancreatic islets induced by high glucose.
Topics: Adolescent; Adult; Arginine; Biguanides; Cadaver; Dose-Response Relationship, Drug; Female; Glucose; Glyburide; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Metformin; Middle Aged | 1999 |
Review of management of type 2 diabetes mellitus.
Topics: Aged; Body Weight; Contraindications; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Outcome Assessment, Health Care; Retrospective Studies | 1998 |
A short term cost-effectiveness model for oral antidiabetic medicines in Europe.
Topics: Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Europe; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Models, Economic | 1998 |
[Impact of intensive blood glucose control with hypoglycemic sulfamides, metformin or insulin on complications of non-insulin dependent diabetes].
Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Risk Factors | 1999 |
Troglitazone and metformin, but not glibenclamide, decrease blood pressure in Otsuka Long Evans Tokushima Fatty rats.
Topics: Animals; Blood Glucose; Blood Pressure; Catecholamines; Chromans; Diabetes Mellitus, Type 2; Glucose Transporter Type 4; Glyburide; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Metformin; Monosaccharide Transport Proteins; Muscle Proteins; Rats; Rats, Inbred OLETF; Thiazoles; Thiazolidinediones; Troglitazone | 1999 |
Metformin but not glyburide prevents high glucose-induced abnormalities in relaxation and intracellular Ca2+ transients in adult rat ventricular myocytes.
Topics: Animals; Blood Glucose; Calcium; Enzyme Inhibitors; Genistein; Glyburide; Heart; Hypoglycemic Agents; Insulin; Male; Metformin; Myocardium; Protein Kinases; Rats; Rats, Sprague-Dawley | 1999 |
Increased glucose intolerance related to digoxin treatment in patients with type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Blood Glucose; Cardiotonic Agents; Diabetes Mellitus, Type 2; Digoxin; Fatal Outcome; Female; Glucose Intolerance; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin | 1999 |
Sensitivity to sulphonylureas in patients with hepatocyte nuclear factor-1alpha gene mutations: evidence for pharmacogenetics in diabetes.
Topics: Adult; Amino Acid Substitution; Chlorpropamide; Diabetes Mellitus, Type 2; DNA Transposable Elements; DNA-Binding Proteins; Female; Glyburide; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Hypoglycemic Agents; Insulin; Metformin; Middle Aged; Nuclear Proteins; Point Mutation; Sulfonylurea Compounds; Transcription Factors | 2000 |
Inhibition of leptin secretion by insulin and metformin in cultured rat adipose tissue.
Topics: Adipose Tissue; Animals; Cells, Cultured; Culture Media; Culture Techniques; Dexamethasone; Glyburide; Hydrocortisone; Hypoglycemic Agents; Insulin; Leptin; Metformin; Rats; Rats, Sprague-Dawley | 2000 |
Glyburide/metformin (Glucovance) for type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Glyburide; Hypoglycemic Agents; Metformin | 2000 |
Oral antidiabetic treatment in patients with coronary disease: time-related increased mortality on combined glyburide/metformin therapy over a 7.7-year follow-up.
Topics: Administration, Oral; Coronary Disease; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Survival Analysis; Time Factors | 2001 |
Transitioning patients with type 2 diabetes to a fixed combination > glyburide/metformin tablet.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Drug Combinations; Glyburide; Humans; Hypoglycemic Agents; Metformin; Tablets | 2000 |
Management of type 2 diabetes: long-awaited evidence of benefits after blood sugar control.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Metformin; Prospective Studies; Treatment Outcome; United Kingdom | 1999 |
A comparison of glyburide and insulin in women with gestational diabetes mellitus.
Topics: Adult; Diabetes, Gestational; Female; Glucose Intolerance; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Placenta; Pregnancy | 2001 |
Roundtable. Blueprint for conversion of patients on metformin and sulfonylurea to Glucovance.
Topics: Counseling; Diabetes Mellitus, Type 2; Drug Combinations; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Metformin; Patient Compliance; Patient Education as Topic; Sulfonylurea Compounds; United States | 2001 |
Lipotoxicity in human pancreatic islets and the protective effect of metformin.
Topics: Arginine; Fatty Acids, Nonesterified; Glucose; Glyburide; Humans; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Metformin; Oleic Acid; Palmitates | 2002 |
Effects of glibenclamide, metformin and insulin on the incidence and latency of death by oubain-induced arrhythmias in mice.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Glucose; Cardiotonic Agents; Female; Glyburide; Insulin; Male; Metformin; Mice; Ouabain | 2002 |
Adherence to oral antidiabetic therapy in a managed care organization: a comparison of monotherapy, combination therapy, and fixed-dose combination therapy.
Topics: Administration, Oral; Aged; Databases, Factual; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Managed Care Programs; Metformin; Middle Aged; Patient Compliance; Retrospective Studies | 2002 |
[Effective reduction of the HbA1c level, fewer side effects. First fixed combination for type 2 diabetic patients].
Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Glycated Hemoglobin; Humans; Metformin | 2002 |
Durability of efficacy and long-term safety profile of glyburide/metformin tablets in patients with type 2 diabetes mellitus: an open-label extension study.
Topics: Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Longitudinal Studies; Male; Metformin; Middle Aged; Postprandial Period; Tablets | 2002 |
Lipid effects of glyburide/metformin tablets in patients with type 2 diabetes mellitus with poor glycemic control and dyslipidemia in an open-label extension study.
Topics: Blood Glucose; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hyperlipidemias; Hypoglycemic Agents; Longitudinal Studies; Male; Metformin; Middle Aged; Risk Factors; Triglycerides | 2002 |
[Severe hypoglycemia caused by sulfonylureas and biguanides in a patient with obstructive anuria: resolution with ureteral stent].
Topics: Aged; Anuria; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Remission Induction; Severity of Illness Index; Stents; Ureteral Obstruction | 2002 |
Treatment of type 2 diabetes: inadequate assessment of oral antidiabetic combinations.
Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Metformin; Randomized Controlled Trials as Topic | 2003 |
Slow response to loss of glycemic control in type 2 diabetes mellitus.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Disease Management; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Health Maintenance Organizations; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Northwestern United States; Registries; Retrospective Studies; United States | 2003 |
The development of an oral antidiabetic combination tablet: design, evaluation and clinical benefits for patients with type 2 diabetes.
Topics: Administration, Oral; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Combinations; Glyburide; Humans; Hypoglycemic Agents; Metformin; Tablets | 2003 |
Urinary PC-1 and N-acetyl-beta-D-glucosaminidase activity in patients with type 2 diabetes treated with metformin, gliclazide or glibenclamide.
Topics: Acetylglucosaminidase; Administration, Oral; Adult; Aged; Creatinine; Diabetes Mellitus, Type 2; Female; Gliclazide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Obesity; Phosphoric Diester Hydrolases; Pyrophosphatases | 2003 |
Economic model of first-line drug strategies to achieve recommended glycaemic control in newly diagnosed type 2 diabetes mellitus.
Topics: Carbamates; Cohort Studies; Decision Trees; Diabetes Mellitus, Type 2; Direct Service Costs; Drug Costs; Drug Therapy, Combination; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Managed Care Programs; Markov Chains; Metformin; Models, Economic; Piperidines; Rosiglitazone; Thiazoles; Thiazolidinediones; United States | 2003 |
A comparison of costs for four oral antidiabetic regimens within a managed care population.
Topics: Administration, Oral; Adolescent; Adult; Aged; California; Carbamates; Cohort Studies; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Health Care Costs; Humans; Hypoglycemic Agents; Insulin; Insurance Claim Review; Male; Managed Care Programs; Metformin; Middle Aged; Piperidines; Retrospective Studies | 2003 |
Nitric oxide generation mediated by beta-adrenoceptors is impaired in platelets from patients with Type 2 diabetes mellitus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Platelets; Cholesterol; Cyclic GMP; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Receptors, Adrenergic, beta; Regression Analysis; Triglycerides | 2003 |
Greater reductions in A1C in type 2 diabetic patients new to therapy with glyburide/metformin tablets as compared to glyburide co-administered with metformin.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Drug Combinations; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Patient Compliance; Regression Analysis; Retrospective Studies; Tablets | 2003 |
Optimal glycemic control in type 2 diabetes mellitus: fasting and postprandial glucose in context.
Topics: Antihypertensive Agents; Blood Glucose; Blood Glucose Self-Monitoring; Carbamates; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Progression; Drug Therapy, Combination; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Metformin; Piperidines; Postprandial Period | 2004 |
Glibenclamide-induced acute haemolytic anaemia revealing a G6PD-deficiency.
Topics: Anemia, Hemolytic; Black People; Blood Glucose; Diabetes Mellitus, Type 2; Drug Administration Schedule; Female; France; Glucosephosphate Dehydrogenase Deficiency; Glyburide; Glycated Hemoglobin; Homozygote; Humans; Insulin; Metformin; Middle Aged; Time Factors | 2004 |
Metformin attenuates progression of carotid arterial wall thickness in patients with type 2 diabetes.
Topics: Arteriosclerosis; Carotid Arteries; Carotid Artery Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Diet Therapy; Drug Administration Schedule; Female; Gliclazide; Glyburide; Glycated Hemoglobin; Humans; Japan; Male; Metformin; Middle Aged; Prospective Studies; Sulfonylurea Compounds; Time Factors; Tunica Intima; Tunica Media | 2004 |
Beneficial effects of triple drug combination of pioglitazone with glibenclamide and metformin in type 2 diabetes mellitus patients on insulin therapy.
Topics: Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones | 2003 |
Reduced serum dipeptidyl peptidase-IV after metformin and pioglitazone treatments.
Topics: Aging; Animals; Blood Glucose; Cell Membrane; Dipeptidyl Peptidase 4; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Glyburide; Hemoglobins; Hypoglycemic Agents; Insulin; Kidney; Liver; Male; Metformin; Peptide Fragments; Pioglitazone; PPAR gamma; Protein Precursors; Rats; Rats, Zucker; Thiazolidinediones | 2004 |
The development and validation of liquid chromatography method for the simultaneous determination of metformin and glipizide, gliclazide, glibenclamide or glimperide in plasma.
Topics: Chromatography, High Pressure Liquid; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Metformin; Reference Standards; Sensitivity and Specificity | 2005 |
Diabetes mellitus in a domesticated Spanish mustang.
Topics: Animals; Area Under Curve; Blood Glucose; Diabetes Mellitus; Female; Glyburide; Horse Diseases; Horses; Hypoglycemic Agents; Islets of Langerhans; Metformin; Treatment Outcome | 2005 |
[Nothing here follows protocol F. Elderly diabetic patients are not "DMP qualified"].
Topics: Aged; Blood Glucose; Comorbidity; Contraindications; Diabetes Mellitus, Type 2; Diabetic Foot; Diabetic Nephropathies; Disease Management; Female; Germany; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Practice Guidelines as Topic; Treatment Refusal | 2005 |
[Use of oral lipid-lowering drugs in patients with type-2 diabetes mellitus].
Topics: Administration, Oral; Aged; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Metformin; Middle Aged | 2005 |
Hypoglycemic effect of Malmea depressa root on streptozotocin diabetic rats.
Topics: Animals; Annonaceae; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Ethanol; Glyburide; Hypoglycemic Agents; Male; Medicine, Traditional; Metformin; Mexico; Plant Extracts; Plant Roots; Rats; Rats, Wistar; Solvents; Water | 2005 |
Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium.
Topics: Adenosine; Adrenergic alpha-Agonists; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diazoxide; Enzyme Activation; Glyburide; Heart Atria; Humans; Hypoglycemic Agents; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Membrane Potentials; Metformin; Mitochondria, Heart; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Potassium Channels; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2006 |
Willingness to pay for inhaled insulin: a contingent valuation approach.
Topics: Administration, Inhalation; Administration, Oral; Adult; Canada; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Financing, Personal; Glyburide; Health Care Surveys; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Patient Satisfaction; Reproducibility of Results; Time Factors | 2005 |
Apparent resolution of type 2 diabetes mellitus after initiation of potent antiretroviral therapy in a man from Africa with HIV infection.
Topics: Antiretroviral Therapy, Highly Active; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; HIV Infections; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged | 2006 |
Insulin secretion and sensitivity as determinants of HbA1c in type 2 diabetes.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Homeostasis; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Male; Metformin; Middle Aged; Regression Analysis | 2006 |
Patient characteristics not described.
Topics: Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Metformin; Patient Selection; Sulfonylurea Compounds | 2006 |
Solid phase extraction--non-aqueous capillary electrophoresis for determination of metformin, phenformin and glyburide in human plasma.
Topics: Electrophoresis, Capillary; Glyburide; Humans; Hypoglycemic Agents; Metformin; Phenformin; Reference Standards; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2006 |
Total cellular calcium and magnesium content of cultured human peripheral blood mononuclear cells following exposure to antidiabetic drugs.
Topics: Adult; Calcium; Cells, Cultured; Diazoxide; Glyburide; Humans; Hypoglycemic Agents; Leukocytes; Magnesium; Metformin; Middle Aged; Potassium Channels; Rosiglitazone; Thiazolidinediones | 2006 |
Improvement in coronary vascular dysfunction produced with euglycaemic control in patients with type 2 diabetes.
Topics: Blood Glucose; Blood Pressure; Case-Control Studies; Coronary Circulation; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburide; Heart Rate; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged | 2007 |
Thiazolidinediones for initial treatment of type 2 diabetes?
Topics: Algorithms; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Thiazolidinediones; Weight Gain | 2006 |
An open, randomized, parallel-group study to compare the efficacy and safety profile of inhaled human insulin (Exubera) with glibenclamide as adjunctive therapy in patients with type 2 diabetes poorly controlled on metformin: response to Barnett et al.
Topics: Administration, Inhalation; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Randomized Controlled Trials as Topic | 2007 |
A comparative study of the effects of hypoglycemic agents on serum electrolytes in the diabetic patients.
Topics: Administration, Oral; Blood Glucose; Calcium; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Electrolytes; Glyburide; Humans; Hypoglycemic Agents; Metformin; Potassium; Sodium; Treatment Outcome | 2007 |
The effects of metformin and glibenclamide on glucose metabolism, counter-regulatory hormones and cardiovascular responses in women with Type 2 diabetes during exercise of moderate intensity.
Topics: Adult; Blood Glucose; Blood Pressure; Brazil; Case-Control Studies; Cholesterol; Diabetes Mellitus, Type 2; Exercise; Female; Glyburide; Hormones; Humans; Hypoglycemic Agents; Metformin; Middle Aged; Postprandial Period | 2007 |
Glycemic durability of monotherapy for diabetes.
Topics: Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Metformin; Rosiglitazone; Thiazolidinediones | 2007 |
[Status of glitazones in treatment of type 2 diabetes mellitus].
Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Disease Management; Drug Costs; Drug Therapy, Combination; Germany; Glyburide; Humans; Hypoglycemic Agents; Long-Term Care; Metformin; Pioglitazone; Practice Guidelines as Topic; Survival Analysis; Thiazolidinediones | 2007 |
[ADOPT study. Glitazone controls diabetes progression].
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Disease Progression; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Long-Term Care; Metformin; Middle Aged; Randomized Controlled Trials as Topic; Rosiglitazone; Thiazolidinediones | 2007 |
Liquid chromatography tandem mass spectrometry method for simultaneous determination of antidiabetic drugs metformin and glyburide in human plasma.
Topics: Chromatography, High Pressure Liquid; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tandem Mass Spectrometry | 2007 |
[ADOPT study: Reevaluation of antidiabetic drugs. Control of diabetes].
Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Disease Progression; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Thiazolidinediones; Treatment Outcome | 2007 |
[Consulting Prof. Dr. Stephan Matthaei. Quakenbrück diabetes center. Prescription relevant conclusions].
Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Long-Term Care; Metformin; Rosiglitazone; Thiazolidinediones; Treatment Outcome | 2007 |
Effect of chronic rosiglitazone, metformin and glyburide treatment on beta-cell mass, function and insulin sensitivity in mZDF rats.
Topics: Animals; Apoptosis; Blood Glucose; Glyburide; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Metformin; Models, Biological; Random Allocation; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones | 2008 |
Insulin as a first-line therapy in type 2 diabetes: should the use of sulfonylureas be halted?
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Sulfonylurea Compounds; Thiazolidinediones | 2008 |
Choosing first-line therapy for management of type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Metformin; Rosiglitazone; Thiazolidinediones | 2008 |
Impact of fixed-dose combination drugs on adherence to prescription medications.
Topics: Adolescent; Adult; Aged; Diabetes Mellitus; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Patient Compliance | 2008 |
Sitagliptin: new drug. Type 2 diabetes: limited efficacy, too many unknown risks.
Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Europe; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Metformin; Pyrazines; Triazoles | 2008 |
Hypoglycaemia in patients with type 2 diabetes treated with a combination of metformin and sulphonylurea therapy in France.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; France; Glipizide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Male; Metformin; Middle Aged; Quality of Life; Stress, Psychological; Sulfonylurea Compounds | 2008 |
Physicochemical interactions of metformin hydrochloride and glibenclamide with several health foods.
Topics: Food-Drug Interactions; Food, Organic; Glyburide; Hypoglycemic Agents; Metformin | 2008 |
Risk of coronary artery disease associated with initial sulphonylurea treatment of patients with type 2 diabetes: a matched case-control study.
Topics: Adult; Case-Control Studies; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Metformin; Middle Aged; Risk; Sulfonylurea Compounds | 2008 |
Sulphonylureas and cancer: a case-control study.
Topics: Aged; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Gliclazide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Neoplasms; Risk Factors; Sulfonylurea Compounds | 2009 |
Use of a claims-based active drug safety surveillance system to assess the risk of acute pancreatitis with exenatide or sitagliptin compared to metformin or glyburide.
Topics: Adolescent; Adult; Databases, Factual; Exenatide; Female; Glyburide; Humans; Hypoglycemic Agents; Insurance, Health; Male; Metformin; Middle Aged; Pancreatitis; Peptides; Pyrazines; Risk Assessment; Safety; Sitagliptin Phosphate; Triazoles; United States; Venoms; Young Adult | 2009 |
Antihyperglycaemic medication modifies factors of postprandial satiety in type 2 diabetes.
Topics: Aged; Amino Acids; Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipeptides; Fasting; Gastric Emptying; Glucagon-Like Peptide 1; Glyburide; Humans; Hunger; Hypoglycemic Agents; Insulin; Leptin; Male; Metformin; Middle Aged; Postprandial Period; Satiation; Thiazolidinediones | 2009 |
[Oral blood glucose-lowering medication as a monotherapy in gestational diabetes: a hotly debated topic].
Topics: Administration, Oral; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Randomized Controlled Trials as Topic; Treatment Outcome | 2009 |
Saxagliptin.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Glucagon-Like Peptide 1; Glyburide; Humans; Metformin; Randomized Controlled Trials as Topic; Treatment Outcome | 2009 |
Hypoglycemic effects of Cecropia pachystachya in normal and alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Cecropia Plant; Diabetes Mellitus; Diabetes Mellitus, Type 2; Flavonoids; Free Radical Scavengers; Glucose Tolerance Test; Glucosides; Glyburide; Hypoglycemic Agents; Male; Medicine, Traditional; Metformin; Phenols; Plant Extracts; Rats; Rats, Wistar | 2010 |
Role of human placental apical membrane transporters in the efflux of glyburide, rosiglitazone, and metformin.
Topics: Adenosine Triphosphate; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cell Polarity; Diabetes, Gestational; Drug Interactions; Female; Glyburide; Humans; Hypoglycemic Agents; Maternal-Fetal Exchange; Metformin; Microvilli; Placenta; Pregnancy; Rosiglitazone; Thiazolidinediones; Tritium | 2010 |
Type 2 diabetes mellitus with pancreatic beta cell dysfunction in 3 horses confirmed with minimal model analysis.
Topics: Animal Feed; Animals; Diabetes Mellitus, Type 2; Diet; Diet Therapy; Female; Glucose Tolerance Test; Glyburide; Horse Diseases; Horses; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Metformin | 2009 |
Antioxidant protective effect of glibenclamide and metformin in combination with honey in pancreas of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Gene Expression Regulation, Enzymologic; Glyburide; Honey; Hypoglycemic Agents; Male; Metformin; Oxidative Stress; Oxidoreductases; Pancreas; Rats; Rats, Sprague-Dawley | 2010 |
Relationships between daily acute glucose fluctuations and cognitive performance among aged type 2 diabetic patients.
Topics: Aged; Aged, 80 and over; Blood Glucose; Cognition; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Thiazolidinediones | 2010 |
Effect of Cyclea peltata Lam. roots aqueous extract on glucose levels, lipid profile, insulin, TNF-alpha and skeletal muscle glycogen in type 2 diabetic rats.
Topics: Animals; Blood Glucose; Cyclea; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Female; Glyburide; Glycogen; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipids; Male; Medicine, Ayurvedic; Metformin; Mice; Muscle, Skeletal; Phytotherapy; Plant Extracts; Plant Roots; Plants, Medicinal; Random Allocation; Rats; Rats, Wistar; Solvents; Tumor Necrosis Factor-alpha; Water | 2010 |
Impaired renal function modifies the risk of severe hypoglycaemia among users of insulin but not glyburide: a population-based nested case-control study.
Topics: Aged; Aged, 80 and over; Canada; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glomerular Filtration Rate; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Kidney Failure, Chronic; Kidney Function Tests; Male; Metformin; Prognosis; Risk Factors; Survival Rate | 2011 |
Effects of metformin on BRIN-BD11 beta-cell insulin secretory desensitization induced by prolonged exposure to sulphonylureas.
Topics: Cell Line; Culture Media; Glyburide; Humans; Insulin-Secreting Cells; Metformin; Sulfonylurea Compounds; Tolbutamide | 2010 |
Interaction of glibenclamide and metformin at the level of translation in pancreatic β cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cell Survival; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Glucose; Glyburide; Hypoglycemic Agents; Insulin-Secreting Cells; Intracellular Signaling Peptides and Proteins; Male; Metformin; Phosphoproteins; Protein Biosynthesis; Proteins; Rats; Rats, Wistar; Ribosomal Protein S6; Signal Transduction; Thionucleotides; TOR Serine-Threonine Kinases | 2011 |
Can modeling of health outcomes facilitate regulatory decision making? The benefit-risk tradeoff for rosiglitazone in 1999 vs. 2007.
Topics: Decision Making, Organizational; Diabetes Mellitus, Type 2; Drug Approval; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Models, Theoretical; Outcome Assessment, Health Care; Quality-Adjusted Life Years; Rosiglitazone; Thiazolidinediones; United States; United States Food and Drug Administration | 2011 |
Influence of CYP2C9 gene polymorphisms on response to glibenclamide in type 2 diabetes mellitus patients.
Topics: Alleles; Amplified Fragment Length Polymorphism Analysis; Aryl Hydrocarbon Hydroxylases; Cohort Studies; Cytochrome P-450 CYP2C9; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Genetic Association Studies; Glyburide; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; India; Male; Metabolic Detoxication, Phase I; Metformin; Middle Aged; Polymorphism, Genetic; Severity of Illness Index | 2011 |
Comparison of antioxidant effects of honey, glibenclamide, metformin, and their combinations in the kidneys of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Glutathione Reductase; Glyburide; Honey; Hypoglycemic Agents; Kidney; Male; Metformin; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2011 |
Glibenclamide or metformin combined with honey improves glycemic control in streptozotocin-induced diabetic rats.
Topics: Animals; Bilirubin; Blood Glucose; Body Weight; Creatinine; Diabetes Mellitus, Experimental; Eating; Fructosamine; Glyburide; Honey; Hypoglycemic Agents; Insulin; Male; Metformin; Rats; Rats, Sprague-Dawley | 2011 |
Pectin from Passiflora edulis shows anti-inflammatory action as well as hypoglycemic and hypotriglyceridemic properties in diabetic rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Biomarkers; Carrageenan; Cells, Cultured; Diabetes Mellitus, Experimental; Edema; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Neutrophils; Nitric Oxide Synthase Type II; Passiflora; Pectins; Peroxidase; Plant Extracts; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2011 |
Oral hypoglycemic agents in pregnancy.
Topics: Administration, Oral; Breast Feeding; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Treatment Outcome | 2011 |
Metformin: an effective attenuator of risperidone-induced insulin resistance hyperglycemia and dyslipidemia in rats.
Topics: Animals; Antipsychotic Agents; Blood Glucose; Disease Models, Animal; Dyslipidemias; Glyburide; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Lipids; Male; Metformin; Rats; Rats, Wistar; Risperidone; Weight Gain | 2011 |
Effects of co-administration of methanol leaf extract of Catharanthus roseus on the hypoglycemic activity of metformin and glibenclamide in rats.
Topics: Animals; Blood Glucose; Catharanthus; Female; Glyburide; Hypoglycemic Agents; Male; Metformin; Mice; Plant Extracts; Plant Leaves; Rats | 2011 |
Simultaneous spectrophotometric determination of metformin hydrochloride and glibenclamide in binary mixtures using combined discrete and continuous wavelet transforms.
Topics: Complex Mixtures; Glyburide; Metformin; Spectrophotometry, Ultraviolet; Wavelet Analysis | 2011 |
Fixed dose combination diabetes medicines - usage in the Australian veteran population.
Topics: Aged; Aged, 80 and over; Australia; Diabetes Mellitus, Type 2; Drug Combinations; Drug Prescriptions; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Practice Patterns, Physicians'; Rosiglitazone; Thiazolidinediones; Veterans | 2011 |
Postmarketing pharmacovigilance of adverse drug reactions: the case of rosiglitazone in Mexico.
Topics: Administration, Oral; Adult; Aged; Diabetes Mellitus, Type 2; Drug Combinations; Edema; Female; Follow-Up Studies; Glyburide; Humans; Hypoglycemic Agents; Male; Medication Adherence; Metformin; Mexico; Middle Aged; Pharmacovigilance; Prospective Studies; Rosiglitazone; Thiazoles; Thiazolidinediones; Weight Gain | 2012 |
Economic evaluation of outpatients with type 2 diabetes mellitus assisted by a pharmaceutical care service.
Topics: Aged; Case-Control Studies; Diabetes Mellitus, Type 2; Family Practice; Female; Glyburide; Health Care Costs; Humans; Hypoglycemic Agents; Insulin; Male; Medication Therapy Management; Metformin; Middle Aged; Prospective Studies | 2011 |
The risk of overall mortality in patients with Type 2 diabetes receiving different combinations of sulfonylureas and metformin: a retrospective analysis.
Topics: Aged; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Retrospective Studies; Risk Factors; Sulfonylurea Compounds | 2012 |
Lactic acidosis, hypotension, and sensorineural hearing loss following intentional metformin overdose.
Topics: Acidosis, Lactic; Drug Overdose; Glyburide; Hearing Loss, Sensorineural; Humans; Hypoglycemia; Hypoglycemic Agents; Hypotension; Male; Metformin; Middle Aged; Respiratory Insufficiency; Suicide, Attempted | 2011 |
High-performance liquid chromatography quadrupole time-of-flight mass spectrometry method for the analysis of antidiabetic drugs in aqueous environmental samples.
Topics: Chromatography, High Pressure Liquid; Drinking Water; Glyburide; Hydrogen-Ion Concentration; Hypoglycemic Agents; Mass Spectrometry; Metformin; Pioglitazone; Reproducibility of Results; Rivers; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Solid Phase Extraction; Thiazolidinediones; Water Pollutants, Chemical | 2012 |
Increase in overall mortality risk in patients with type 2 diabetes receiving glipizide, glyburide or glimepiride monotherapy versus metformin: a retrospective analysis.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Kaplan-Meier Estimate; Male; Metformin; Middle Aged; Propensity Score; Retrospective Studies; Sulfonylurea Compounds; Young Adult | 2012 |
Bioassay-guided antidiabetic study of Phaleria macrocarpa fruit extract.
Topics: Animals; Biological Assay; Biological Transport; Blood Glucose; Chemical Fractionation; Diabetes Mellitus, Experimental; Female; Fruit; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; Insulin; Jejunum; Male; Metformin; Methanol; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Solvents; Thymelaeaceae | 2012 |
Glycaemic control and cost analysis when changing from gliclazide co-administered with metformin to pre-combined glibenclamide-metformin tablets in type 2 diabetes mellitus.
Topics: Blood Glucose; Costs and Cost Analysis; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gliclazide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Retrospective Studies; Tablets | 2012 |
Prescription patterns for diabetes mellitus and therapeutic implications: a population-based analysis.
Topics: Administration, Oral; Analysis of Variance; Brazil; Delivery of Health Care; Diabetes Mellitus; Drug Prescriptions; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Population Surveillance | 2012 |
Differential effects of 3 classes of antidiabetic drugs on olanzapine-induced glucose dysregulation and insulin resistance in female rats.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Female; Glucose Intolerance; Glyburide; Hypoglycemic Agents; Insulin Resistance; Metformin; Olanzapine; Rats; Rosiglitazone; Thiazolidinediones | 2012 |
Glibenclamide-pregnenolone derivative has greater hypoglycemic effects and biodistribution than glibenclamide-OH in alloxan-rats.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Drug Combinations; Female; Glyburide; Hypoglycemic Agents; Metformin; Pregnenolone; Rats; Rats, Wistar; Tissue Distribution | 2012 |
Treatment persistence, hypoglycaemia and clinical outcomes in type 2 diabetes patients with dipeptidyl peptidase-4 inhibitors and sulphonylureas: a primary care database analysis.
Topics: Blood Glucose; Databases, Factual; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Germany; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Medication Adherence; Metformin; Middle Aged; Primary Health Care; Retrospective Studies; Sulfonylurea Compounds | 2013 |
Rapid extraction, identification and quantification of oral hypoglycaemic drugs in serum and hair using LC-MS/MS.
Topics: Acetonitriles; Chromatography, Liquid; Female; Forensic Toxicology; Gliclazide; Glipizide; Glyburide; Hair; Humans; Hypoglycemic Agents; Limit of Detection; Male; Mass Spectrometry; Metformin; Methanol; Middle Aged; Molecular Structure; Solvents; Sulfonylurea Compounds | 2012 |
Fast and environmentally friendly quantitative analysis of active agents in anti-diabetic tablets by an alternative laser-induced breakdown spectroscopy (LIBS) method and comparison to a validated reversed-phase high-performance liquid chromatography (RP-
Topics: Analysis of Variance; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Glyburide; Hypoglycemic Agents; Linear Models; Metformin; Reproducibility of Results; Spectrum Analysis; Tablets | 2012 |
Medication dyes as a source of drug allergy.
Topics: Adolescent; Aged; Coloring Agents; Dermatitis, Atopic; Drug Hypersensitivity; Excipients; Female; Food Coloring Agents; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Pharmaceutical Preparations; Pruritus; Skin | 2013 |
Octreotide: a novel therapy for refractory sulfonylurea-induced hypoglycemia.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Middle Aged; Octreotide | 2013 |
Evaluation of toxic effects of metformin hydrochloride and glibenclamide on some organs of male rats.
Topics: Animals; Antioxidants; Down-Regulation; Glyburide; Hypoglycemic Agents; Kidney; Lipid Peroxidation; Liver; Male; Metformin; Random Allocation; Rats; Testis; Up-Regulation | 2012 |
Mortality outcomes of different sulphonylurea drugs: the results of a 14-year cohort study of type 2 diabetic patients.
Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Confounding Factors, Epidemiologic; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Follow-Up Studies; Gliclazide; Glyburide; Humans; Hypoglycemic Agents; Insulin; Kaplan-Meier Estimate; Male; Metformin; Middle Aged; Neoplasms; Odds Ratio; Proportional Hazards Models; Research Design; Retrospective Studies; Risk Assessment; Risk Factors; Sulfonylurea Compounds; Tolbutamide | 2013 |
[Diabetes treatment in patients with chronic kidney disease].
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Substitution; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Kidney Failure, Chronic; Kidney Function Tests; Male; Metformin; Pyrazines; Sitagliptin Phosphate; Triazoles | 2013 |
Inflammation and cognitive dysfunction in type 2 diabetic carotid endarterectomy patients.
Topics: Aged; Cognition Disorders; Diabetes Mellitus, Type 2; Endarterectomy, Carotid; Glyburide; Humans; Hypoglycemic Agents; Inflammation; Logistic Models; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Sulfonylurea Compounds; Triazoles | 2013 |
The influence on DNA damage of glycaemic parameters, oral antidiabetic drugs and polymorphisms of genes involved in the DNA repair system.
Topics: Administration, Oral; Adult; Aged; Comet Assay; Cross-Sectional Studies; Diabetes Mellitus, Type 2; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Micronucleus Tests; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; X-ray Repair Cross Complementing Protein 1 | 2013 |
Mortality among veterans with type 2 diabetes initiating metformin, sulfonylurea or rosiglitazone monotherapy.
Topics: Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Proportional Hazards Models; Retrospective Studies; Risk Factors; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Time Factors; United States; Veterans | 2013 |
Vildagliptin monotherapy. To be avoided, like other DPP-4 inhibitors.
Topics: Adamantane; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glyburide; Humans; Hypoglycemic Agents; Metformin; Nitriles; Pyrrolidines; Vildagliptin | 2013 |
Oral hypoglycaemic agents and the development of non-fatal cardiovascular events in patients with type 2 diabetes mellitus.
Topics: Administration, Oral; Adult; Aged; Cardiovascular Diseases; Cohort Studies; Comorbidity; Coronary Disease; Diabetes Mellitus, Type 2; Dyslipidemias; Female; Glyburide; Humans; Hypertension; Hypoglycemic Agents; Incidence; Male; Metformin; Middle Aged; Retrospective Studies; Sulfonylurea Compounds; Taiwan | 2013 |
Antidiabetic-drug combination treatment for glucose intolerance in adult female rats treated acutely with olanzapine.
Topics: Animals; Benzodiazepines; Disease Models, Animal; Drug Therapy, Combination; Fasting; Female; Glucose Intolerance; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; Insulin; Metformin; Olanzapine; Rats; Rats, Sprague-Dawley; Rosiglitazone; Selective Serotonin Reuptake Inhibitors; Thiazolidinediones; Time Factors | 2014 |
Glibenclamide reduces pro-inflammatory cytokine production by neutrophils of diabetes patients in response to bacterial infection.
Topics: Burkholderia pseudomallei; Diabetes Mellitus, Type 2; Disease Susceptibility; Glyburide; Humans; Hypoglycemic Agents; Interleukin-1beta; Interleukin-8; Melioidosis; Metformin; Neutrophils; Thailand | 2013 |
Metformin/glibenclamide-related interstitial lung disease: a case report.
Topics: Administration, Oral; Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Drug Substitution; Female; Glyburide; Humans; Hypoglycemic Agents; Iatrogenic Disease; Insulin; Lung Diseases, Interstitial; Metformin; Respiratory Function Tests; Risk Factors; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
Quantitative determination of metformin, glyburide and its metabolites in plasma and urine of pregnant patients by LC-MS/MS.
Topics: Adult; Chromatography, High Pressure Liquid; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Metformin; Pregnancy; Sensitivity and Specificity; Tandem Mass Spectrometry | 2015 |
Evaluation approach can significantly influence oral glucose-lowering drugs total mortality risks in retrospective cohorts of type 2 diabetes mellitus patients.
Topics: Diabetes Mellitus, Type 2; Gliclazide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Metformin; Registries; Retrospective Studies; Risk Factors; Treatment Outcome; Ukraine | 2014 |
Fast and Simultaneous Analysis of Combined Anti-Diabetic Drugs by Capillary Zone Electrophoresis.
Topics: Drug Combinations; Electrophoresis, Capillary; Gliclazide; Glyburide; Hypoglycemic Agents; Limit of Detection; Linear Models; Metformin; Reproducibility of Results; Tablets | 2015 |
Metformin promotes irisin release from murine skeletal muscle independently of AMP-activated protein kinase activation.
Topics: AMP-Activated Protein Kinases; Animals; Biomarkers; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Activation; Fibronectins; Glyburide; Hypoglycemic Agents; Male; Metformin; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Protein Kinase Inhibitors; RNA Interference; RNA, Messenger; Signal Transduction; Transfection; Up-Regulation | 2015 |
Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study.
Topics: Aged; Carbamates; Cardiovascular Diseases; Denmark; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Morbidity; Myocardial Infarction; Piperidines; Registries; Retrospective Studies; Risk Factors; Stroke; Sulfonylurea Compounds; Tolbutamide | 2015 |
Trends in prevalence, incidence and pharmacologic management of diabetes mellitus among seniors newly admitted to long-term care facilities in Saskatchewan between 2003 and 2011.
Topics: Aged; Aged, 80 and over; Diabetes Mellitus; Female; Glyburide; Homes for the Aged; Humans; Hypoglycemic Agents; Incidence; Insulin; Long-Term Care; Male; Metformin; Prevalence; Retrospective Studies; Saskatchewan | 2015 |
Which oral hypoglycaemic for gestational diabetes?
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2015 |
Time to and factors associated with insulin initiation in patients with type 2 diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Colombia; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Kaplan-Meier Estimate; Male; Metformin; Middle Aged; Retrospective Studies; Socioeconomic Factors; Time Factors; Time-to-Treatment; Young Adult | 2015 |
Estimating kidney function and use of oral antidiabetic drugs in elderly.
Topics: Administration, Oral; Age Factors; Aged; Aged, 80 and over; Biomarkers; Creatinine; Cross-Sectional Studies; Diabetes Mellitus; Diabetic Nephropathies; Female; Germany; Glomerular Filtration Rate; Glyburide; Humans; Hypoglycemic Agents; Kidney; Male; Metformin; Models, Biological; Predictive Value of Tests; Prevalence; Renal Elimination; Renal Insufficiency, Chronic; Risk Factors | 2015 |
Endoplasmic reticulum stress is increased in adipose tissue of women with gestational diabetes.
Topics: Adipose Tissue; Adult; Biomarkers; Caspase 1; Connexins; Diabetes, Gestational; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Female; Glyburide; Humans; Inflammasomes; Interleukin-1alpha; Interleukin-1beta; Lipopolysaccharides; Male; Metformin; Mothers; Nerve Tissue Proteins; Obesity; Poly I-C; Pregnancy; Thapsigargin; Tumor Necrosis Factor-alpha | 2015 |
Diabetes: Therapy for gestational diabetes mellitus--time for a change?
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2015 |
In women with gestational diabetes requiring drug treatment, glibenclamide may be inferior to insulin and metformin: metformin (plus insulin when required) performs better than insulin.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2015 |
Changing Patterns of Glucose-Lowering Medication Use in VA Nursing Home Residents With Diabetes, 2005 to 2011.
Topics: Aged; Aged, 80 and over; Cohort Studies; Diabetes Mellitus; Drug Utilization; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Nursing Homes; Practice Patterns, Physicians'; Retrospective Studies; Sulfonylurea Compounds; Thiazolidinediones; United States; United States Department of Veterans Affairs | 2015 |
Comparative Study of the Antioxidant Effects of Metformin, Glibenclamide, and Repaglinide in Alloxan-Induced Diabetic Rats.
Topics: Alloxan; Animals; Antioxidants; Biomarkers; Blood Glucose; Carbamates; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Glutathione; Glyburide; Hypoglycemic Agents; Lipid Peroxidation; Male; Malondialdehyde; Metformin; Oxidative Stress; Piperidines; Rats; Superoxide Dismutase | 2016 |
Role of the antidiabetic drugs: Glibenclamide and metformin on the contractility of isolated rat uteri.
Topics: Animals; Female; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Metformin; Rats; Uterine Contraction | 2016 |
Combination Therapy of Nifedipine and Sulphonylureas Exhibits a Mutual Antagonistic Effect on the Endothelial Cell Dysfunction Induced by Hyperglycemia Linked to Vascular Disease.
Topics: Antihypertensive Agents; Biphenyl Compounds; Cell Movement; Diabetic Angiopathies; Drug Synergism; Endothelial Cells; Glucose; Glyburide; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Hypoglycemic Agents; Irbesartan; Metformin; Nifedipine; Oxygen; Sulfonylurea Compounds; Tetrazoles | 2016 |
Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats.
Topics: Administration, Intravenous; Animals; Biotransformation; Canagliflozin; Chromans; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Glyburide; Hepatocytes; Humans; Hypoglycemic Agents; Liver; Male; Metformin; Rats, Sprague-Dawley; Rats, Zucker; Rosiglitazone; Species Specificity; Substrate Specificity; Sulfotransferases; Thiazolidinediones; Troglitazone | 2016 |
Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemia; Hypoglycemic Agents; Incidence; Male; Metformin; Middle Aged; Myocardial Infarction; Proportional Hazards Models; Risk Factors; Sulfonylurea Compounds; Sweden | 2016 |
Non-insulin pharmacological therapy in pregnancy.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome | 2016 |
Evaluation, efficacy and tolerability of GlucoNovax tablet in type 2 diabetic patients.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Quality of Life; Sulfonylurea Compounds; Tablets; Treatment Outcome | 2016 |
Metformin Ameliorates Dysfunctional Traits of Glibenclamide- and Glucose-Induced Insulin Secretion by Suppression of Imposed Overactivity of the Islet Nitric Oxide Synthase-NO System.
Topics: Animals; Dose-Response Relationship, Drug; Female; Glucose; Glyburide; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Metformin; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Up-Regulation | 2016 |
All-Cause and Cardiovascular Mortality following Treatment with Metformin or Glyburide in Patients with Type 2 Diabetes Mellitus.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Coronary Angiography; Coronary Artery Bypass; Coronary Artery Disease; Coronary Care Units; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Iran; Male; Metformin; Middle Aged; Myocardial Infarction; Protective Factors; Retrospective Studies; Risk Factors; Stroke | 2017 |
Population pharmacokinetics of carvedilol enantiomers and their metabolites in healthy subjects and type-2 diabetes patients.
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Carbazoles; Carvedilol; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP2D6; Diabetes Mellitus, Type 2; Female; Glyburide; Healthy Volunteers; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Propanolamines; Stereoisomerism | 2017 |
Effectiveness and clinical inertia in patients with antidiabetic therapy.
Topics: Adult; Aged; Colombia; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Glargine; Male; Metformin; Middle Aged; Practice Patterns, Physicians'; Retrospective Studies | 2017 |
Comment on Nachum et al. Glyburide Versus Metformin and Their Combination for the Treatment of Gestational Diabetes Mellitus: A Randomized Controlled Study. Diabetes Care 2017;40:332-337.
Topics: Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2017 |
Response to Comment on Nachum et al. Glyburide Versus Metformin and Their Combination for the Treatment of Gestational Diabetes Mellitus: A Randomized Controlled Study. Diabetes Care 2017;40:332-337.
Topics: Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy | 2017 |
Murraya paniculata (L.) (Orange Jasmine): Potential Nutraceuticals with Ameliorative Effect in Alloxan-Induced Diabetic Rats.
Topics: Alloxan; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dietary Supplements; Glyburide; Hypoglycemic Agents; India; Liver; Male; Medicine, Traditional; Metformin; Murraya; Pancreas; Plant Extracts; Rats; Rats, Wistar; Triglycerides | 2017 |
Glibenclamide Mimics Metabolic Effects of Metformin in H9c2 Cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cell Line; Electron Transport Chain Complex Proteins; Energy Metabolism; Glyburide; Glycolysis; Hypoglycemic Agents; L-Lactate Dehydrogenase; Metformin; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation; Oxygen Consumption; Phosphofructokinase-1; Phosphorylation; Pyruvate Kinase; Rats | 2017 |
Combination of Rheum ribes and Metformin Against Diabetes, Thermal Hyperalgesia, and Tactile Allodynia in a Mice Model.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Glyburide; Hyperalgesia; Hypoglycemic Agents; Male; Metformin; Mice; Pain Threshold; Phytotherapy; Plant Extracts; Plants, Medicinal; Rheum; Ribes | 2018 |
Pulse pressure and diabetes treatments: Blood pressure and pulse pressure difference among glucose lowering modality groups in type 2 diabetes.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Cohort Studies; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucose; Glyburide; Humans; Hypoglycemic Agents; Insulin; Iran; Male; Metformin; Middle Aged; Outcome and Process Assessment, Health Care; Retrospective Studies | 2018 |
Pharmacological treatment of gestational diabetes mellitus: point/counterpoint.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Pregnancy; Pregnancy Outcome; Treatment Outcome | 2018 |
CYP2C9*3 gene variant contributes independently to glycaemic control in patients with type 2 diabetes treated with glibenclamide.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Cross-Sectional Studies; Cytochrome P-450 CYP2C9; Diabetes Mellitus, Type 2; Female; Genetic Variation; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Logistic Models; Male; Metformin; Mexico; Middle Aged; Multivariate Analysis; Polymorphism, Genetic; Time Factors; Treatment Outcome | 2018 |
A herbal treatment for type 2 diabetes adulterated with undisclosed drugs.
Topics: Diabetes Mellitus, Type 2; Drug Contamination; Female; Glyburide; Humans; Hypoalbuminemia; Hypoglycemia; Hypoglycemic Agents; Metformin; Middle Aged; Plant Preparations | 2018 |
Side effects of frequently used oral antidiabetics on wound healing in vitro.
Topics: Administration, Oral; Apoptosis; Carbamates; Caspases; Cell Line; Endopeptidases; Fibroblasts; Gelatinases; Glyburide; Humans; Hypoglycemic Agents; Keratinocytes; Membrane Proteins; Metformin; Piperidines; Receptors, CXCR4; Serine Endopeptidases; Sitagliptin Phosphate; Wound Healing | 2019 |
Multi-target antidiabetic mechanisms of mexicanolides from Swietenia humilis.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; Limonins; Liver; Male; Meliaceae; Metformin; Mexico; Mice, Inbred ICR; Pancreas; Plants, Medicinal | 2019 |
Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms.
Topics: Analgesics; Animals; Disease Models, Animal; Female; Glyburide; Hyperalgesia; Metformin; Mice; Naltrexone; Neuralgia; Nociception; Psychomotor Performance; Receptors, Opioid | 2019 |
The influence of drug solubility and sampling frequency on metformin and glibenclamide release from double-layered particles: experimental analysis and mathematical modelling.
Topics: Drug Carriers; Glyburide; Metformin; Organosilicon Compounds; Polymers; Solubility | 2019 |
A Sensitive HPTLC Method for the Estimation of Glibenclamide, Rosiglitazone Maleate and Metformin Hydrochloride from a Multicomponent Dosage Form.
Topics: Calibration; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glyburide; Limit of Detection; Metformin; Reproducibility of Results; Rosiglitazone; Tablets | 2020 |
Time to modification of antidiabetic therapy in patients over the age of 65 years with newly diagnosed diabetes mellitus.
Topics: Administration, Oral; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Combination; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Prognosis; Retrospective Studies; Sodium-Glucose Transporter 2 Inhibitors; Sulfonylurea Compounds; Survival Rate; Time Factors | 2020 |
Metformin-induced suppression of IFN-α via mTORC1 signalling following seasonal vaccination is associated with impaired antibody responses in type 2 diabetes.
Topics: Aged; Antibodies, Viral; Antibody Affinity; Antibody Formation; Diabetes Mellitus, Type 2; Female; Glyburide; Hemagglutination Inhibition Tests; Humans; Immunoglobulin G; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza Vaccines; Interferon-alpha; Male; Mechanistic Target of Rapamycin Complex 1; Metformin; Monocytes; Seasons; Signal Transduction; Vaccination; Virion | 2020 |
Comparative effects of glibenclamide, metformin and insulin on fetal pancreatic histology and maternal blood glucose in pregnant streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes, Gestational; Female; Fetal Development; Glyburide; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Metformin; Pancreas; Pregnancy; Rats; Rats, Sprague-Dawley; Streptozocin | 2019 |
Retinoprotection by BGP-15, a Hydroximic Acid Derivative, in a Type II Diabetic Rat Model Compared to Glibenclamide, Metformin, and Pioglitazone.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Models, Animal; Electroretinography; Glyburide; Humans; Hydroxamic Acids; Hypoglycemic Agents; Insulin; Male; Metformin; Molecular Structure; Oximes; Pioglitazone; Piperidines; Protective Agents; Rats; Rats, Wistar; Retina | 2020 |
Development and characterization of metformin hydrochloride- and glyburide-containing orally disintegrating tablets.
Topics: Administration, Oral; Caco-2 Cells; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Freeze Drying; Glyburide; Hardness; Humans; Metformin; Permeability; Powders; Solubility; Tablets | 2020 |
Characterization of women with gestational diabetes who failed to achieve glycemic control by lifestyle modifications.
Topics: Adult; Blood Glucose; Body Mass Index; Diabetes, Gestational; Female; Glucose Tolerance Test; Glyburide; Glycemic Control; Humans; Hypoglycemic Agents; Insulin; Life Style; Metformin; Pregnancy; Retrospective Studies; Treatment Outcome | 2021 |
Sensitive detection of antidiabetic compounds and one degradation product in wastewater samples by a new SPE-LC-MS/MS method.
Topics: Chromatography, Liquid; Environmental Monitoring; Gliclazide; Glipizide; Glyburide; Hypoglycemic Agents; Metformin; Reproducibility of Results; Solid Phase Extraction; Sulfonylurea Compounds; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2021 |
Angiotensin-Converting Enzyme Inhibitors Used Concomitantly with Insulin Secretagogues and the Risk of Serious Hypoglycemia.
Topics: Administrative Claims, Healthcare; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Carbamates; Databases, Factual; Diabetes Mellitus, Type 2; Drug Interactions; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Medicaid; Metformin; Middle Aged; Nateglinide; Pharmacoepidemiology; Piperidines; Secretagogues; Sulfonylurea Compounds; United States | 2022 |
Changing patterns in medication prescription for gestational diabetes during a time of guideline change in the USA: a cross-sectional study.
Topics: Adolescent; Adult; Cross-Sectional Studies; Diabetes, Gestational; Drug Prescriptions; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Metformin; Middle Aged; Practice Patterns, Physicians'; Pregnancy; Prenatal Care; United States; Young Adult | 2022 |
Correlates of Insulin Selection as a First-Line Pharmacological Treatment for Gestational Diabetes.
Topics: Administration, Oral; Adult; Analysis of Variance; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Healthcare Disparities; Hispanic or Latino; Humans; Hypoglycemic Agents; Insulin; Medically Uninsured; Metformin; Practice Patterns, Physicians'; Pregnancy; Retrospective Studies | 2022 |
Bridelia ferruginea Benth. (Euphorbiaceae) mitigates oxidative imbalance and lipotoxicity, with concomitant modulation of insulin signaling pathways via GLUT4 upregulation in hepatic tissues of diabetic rats.
Topics: Animals; Catalytic Domain; Diabetes Mellitus, Type 2; Euphorbiaceae; Gene Expression Regulation; Glucose Transporter Type 4; Glyburide; Insulin; Lipid Peroxidation; Liver; Male; Metformin; Models, Molecular; Molecular Docking Simulation; Oxidative Stress; Phytotherapy; Plant Extracts; Plant Leaves; Protein Conformation; Rats; Rats, Sprague-Dawley; Signal Transduction; Up-Regulation | 2022 |
Synergistic antidiabetic activity of Taraxacum officinale (L.) Weber ex F.H.Wigg and Momordica charantia L. polyherbal combination.
Topics: Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Synergism; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; Male; Metformin; Momordica charantia; Myoblasts; Plant Extracts; Rats; Rats, Sprague-Dawley; Rats, Wistar; Streptozocin; Taraxacum | 2022 |
Spectroscopic interactions of non-insulin-dependent diabetes mellitus with levocetirizine.
Topics: Cetirizine; Drug Interactions; Glyburide; Hypoglycemic Agents; Metformin; Molecular Structure; Solutions; Spectrophotometry, Ultraviolet | 2021 |
Comparative efficacy and safety of glyburide, metformin, and insulin in treatment of gestational diabetes mellitus: A protocol for systematic review and meta-analysis.
Topics: Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Meta-Analysis as Topic; Metformin; Pregnancy; Systematic Reviews as Topic | 2022 |
Effects of Combined
Topics: Animals; Aryldialkylphosphatase; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Garcinia kola; Glyburide; Hypoglycemic Agents; Insulin; Male; Metformin; Niacinamide; Plant Extracts; Rats; Rats, Wistar; Streptozocin | 2022 |
Effects of antidiabetic agents on Alzheimer's disease biomarkers in experimentally induced hyperglycemic rat model by streptozocin.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Biomarkers; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Donepezil; Glucose; Glyburide; Glycated Hemoglobin; Hypoglycemic Agents; Insulin Glargine; Male; Malondialdehyde; Metformin; Microtubule-Associated Proteins; Nitric Oxide; Rats; Rats, Wistar; Streptozocin; Triglycerides; Tumor Necrosis Factor-alpha | 2022 |
Efficacy and safety of hypoglycemic agents on gestational diabetes mellitus in women: A Bayesian network analysis of randomized controlled trials.
Topics: Birth Weight; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Infant, Newborn; Insulin; Metformin; Pregnancy; Randomized Controlled Trials as Topic | 2022 |
Crude extract from
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Euphorbia; Gliclazide; Glyburide; Hypoglycemic Agents; Insulin; Metformin; Plant Extracts; Rats | 2023 |
Signal Suppression in LC-ESI-MS/MS from Concomitant Medications and Its Impact on Quantitative Studies: An Example Using Metformin and Glyburide.
Topics: Chromatography, Liquid; Glyburide; Isotopes; Metformin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2023 |
Co-administration of metformin and/or glibenclamide with losartan reverse N
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Esters; Glyburide; Hypertension; Hypoglycemic Agents; Losartan; Metformin; NG-Nitroarginine Methyl Ester; Rats; Streptozocin; Water | 2023 |
Idealistic, realistic, and unrealistic expectations of pharmacological treatment in persons with type 2 diabetes in primary care.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Glyburide; Humans; Insulin; Metformin; Motivation; Primary Health Care | 2023 |
Analytical Method Capable of Quantifying Eight Nitrosamine Impurities from Five Different Commercially Available Metformin Formulations with Glipizide, Glibenclamide, Gliclazide, Evogliptin, and Glimepiride by Ultra High Performance Liquid Chromatography
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Diabetes Mellitus, Type 2; Gliclazide; Glipizide; Glyburide; Humans; Metformin; Nitrosamines; Pharmaceutical Preparations; Tandem Mass Spectrometry | 2023 |
[Cost-effectiveness of treatment of type 2 diabetes mellitus in México].
Topics: Cost-Benefit Analysis; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Insulin, Isophane; Metformin; Mexico | 2023 |
Single versus Double Coffee-Ring Effect Patterns in Thin-Layer Chromatography Coupled with Surface-Enhanced Raman Spectroscopic Analysis of Anti-Diabetic Drugs Adulterated in Herbal Products.
Topics: Chromatography, Thin Layer; Glyburide; Metal Nanoparticles; Metformin; Silver; Spectrum Analysis, Raman | 2023 |
[Characteristics of purchases of hypoglycemic agents in pharmacy retail sector in 2016-2020 years dynamics].
Topics: Dipeptidyl Peptidase 4; Gliclazide; Glyburide; Humans; Hypoglycemic Agents; Metformin; Pharmacies; Pharmacy | 2023 |