Compounds > glyburide

glyburide and loperamide

glyburide has been researched along with loperamide in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (25.00)	29.6817
2010's	9 (75.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Baamonde, A; García, V; Hidalgo, A; Juárez, L; Menéndez, L	1
Chen, IH; Cheng, JT; Tong, YC; Yu, BC	1
Chen, ZC; Cheng, JT; Chung, HH; Hung, CH; Lin, HJ; Shieh, JP	1
Cheng, JT; Chung, HH; Lee, LM; Lin, CS; Lin, KC	1
Chen, W; Cheng, JT; Chung, HH	1

Reviews

2 review(s) available for glyburide and loperamide

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

10 other study(ies) available for glyburide and loperamide

Article	Year
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
Involvement of nitric oxide in the inhibition of bone cancer-induced hyperalgesia through the activation of peripheral opioid receptors in mice. Neuropharmacology, 2007, Volume: 53, Issue:1 Topics: Analysis of Variance; Animals; Bone Neoplasms; Carbazoles; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Glyburide; Hyperalgesia; Indoles; Loperamide; Mice; Mice, Inbred C3H; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Pain Measurement; Receptors, Opioid	2007
Loperamide-induced rat prostate relaxation through activation of peripheral µ-opioid receptors. Neurourology and urodynamics, 2011, Volume: 30, Issue:3 Topics: Analysis of Variance; Animals; Blotting, Western; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; Loperamide; Male; Muscle Relaxation; Naloxone; Narcotic Antagonists; Potassium; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Prostate; Rats; Rats, Wistar; Receptors, Opioid, mu	2011
Activation of peripheral opioid µ-receptors in blood vessel may lower blood pressure in spontaneously hypertensive rats. Pharmacology, 2011, Volume: 87, Issue:5-6 Topics: Animals; Arteries; Blood Pressure; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium; Glyburide; Hemodynamics; Intracellular Signaling Peptides and Proteins; KATP Channels; Loperamide; Male; Morphinans; Naloxone; Phenylephrine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Opioid, mu; Vasodilation	2011
Urinary bladder relaxation through activation of opioid μ-receptors induced by loperamide is increased in diabetic rats. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2012, Volume: 120, Issue:6 Topics: Animals; Antidiarrheals; Cells, Cultured; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic Agents; Loperamide; Male; Muscle Relaxation; Muscle, Smooth; Naloxone; Narcotic Antagonists; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Opioid, mu; Streptozocin; Urinary Bladder	2012
Opiate-induced constipation related to activation of small intestine opioid μ2-receptors. World journal of gastroenterology, 2012, Mar-28, Volume: 18, Issue:12 Topics: Acetylcholine; Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gastrointestinal Transit; Glyburide; Humans; Intestine, Small; Loperamide; Male; Mice; Mice, Inbred BALB C; Morphinans; Muscle Relaxation; Naloxone; Receptors, Opioid, mu	2012