glyburide and diclofenac

glyburide has been researched along with diclofenac in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.06)18.2507
2000's21 (63.64)29.6817
2010's10 (30.30)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Darvesh, AS; Geldenhuys, WJ; Leeper, TC; Morris, DL; Sullivan, PG; Yonutas, HM1
Appel, S; Hitzenberger, G; Kalafsky, G; Kallay, Z; Kutz, K; Rüfenacht, T; Tetzloff, W1
Hutri-Kähönen, N; Kähönen, M; Pörsti, I; Sallinen, K; Tolvanen, JP; Wu, X1
Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI; Rosas, R; Vidal-Cantú, GC1
Castañeda-Hernández, G; Granados-Soto, V; Ortiz, MI; Rosas, R; Torres-López, JE; Vidal-Cantú, GC2
Buckelman, A; Hauser, D; Katz, H; Klayman, G; Pollack, A; Rechtman, E1
Mannesse, CK; van der Cammen, TJ1
Alves, DP; Duarte, ID; Leite, R; Tatsuo, MA1
Castañeda-Hernández, G; Granados-Soto, V; Lozano-Cuenca, J1
Fujimoto, S; Kunimatsu, M; Mori, M; Tsushima, H1
Birkenmeier, K; Felix, SB; Janke, I; Krieg, T; Labitzke, C; Landsberger, M; Prange, T; Schunck, WH; Stangl, V; Staudt, A; Trimpert, C1
Berti, F; Del Soldato, P; Manfredi, B; Rossoni, G; Sparatore, A; Tazzari, V1
Cairns, BE; Dong, XD; Mann, MK; Mok, E; Svensson, P1
Castañeda-Hernández, G; León-Reyes, MR; Ortiz, MI2
Cankar, K; Hojs, N; Strucl, M1
Gu, Y; Hu, Y; Huang, K; Ji, Z; Li, X; Pan, S1

Reviews

2 review(s) available for glyburide and diclofenac

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for glyburide and diclofenac

ArticleYear
Lack of interaction between fluvastatin and oral hypoglycemic agents in healthy subjects and in patients with non-insulin-dependent diabetes mellitus.
    The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2

    Topics: Administration, Oral; Anticholesteremic Agents; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Glyburide; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Insulin; Lovastatin; Placebos; Simvastatin; Tolbutamide

1995

Other Studies

30 other study(ies) available for glyburide and diclofenac

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Identification of small molecules that bind to the mitochondrial protein mitoNEET.
    Bioorganic & medicinal chemistry letters, 2016, 11-01, Volume: 26, Issue:21

    Topics: Hypoglycemic Agents; Ligands; Mitochondrial Proteins; Protein Binding; Small Molecule Libraries; Thiazolidinediones

2016
Ramipril therapy improves arterial dilation in experimental hypertension.
    Cardiovascular research, 1997, Volume: 33, Issue:1

    Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Cyclooxygenase Inhibitors; Diclofenac; Endothelium, Vascular; Glyburide; Hypertension; In Vitro Techniques; Isoproterenol; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Potassium Channel Blockers; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation

1997
Evidence for a new mechanism of action of diclofenac: activation of K+ channels.
    Proceedings of the Western Pharmacology Society, 2001, Volume: 44

    Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Behavior, Animal; Diclofenac; Female; Formaldehyde; Glyburide; Hypoglycemic Agents; KATP Channels; Pain Measurement; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar

2001
Pharmacological evidence for the activation of K(+) channels by diclofenac.
    European journal of pharmacology, 2002, Mar-01, Volume: 438, Issue:1-2

    Topics: 4-Aminopyridine; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Female; Formaldehyde; Glyburide; Hindlimb; Morphine; Pain; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide

2002
Role of the nitric oxide-cyclic GMP-K+ channel pathway in the antinociception induced by atrial natriuretic peptide (ANP) and diclofenac.
    Proceedings of the Western Pharmacology Society, 2002, Volume: 45

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Atrial Natriuretic Factor; Charybdotoxin; Cyclic GMP; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pain Measurement; Potassium Channels; Quinoxalines; Rats; Rats, Wistar; Tolbutamide

2002
Keratic precipitates and iris nodules after uneventful phacoemulsification in diabetic patients.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:12

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Corneal Diseases; Diabetes Complications; Diabetes Mellitus; Diclofenac; Glyburide; Humans; Hypoglycemic Agents; Iris Diseases; Male; Phacoemulsification; Postoperative Complications

2002
[Adverse drug reactions in three older patients, even without changes in medication].
    Nederlands tijdschrift voor geneeskunde, 2003, Mar-29, Volume: 147, Issue:13

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diclofenac; Digoxin; Diuretics; Drug Interactions; Female; Furosemide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Hypotension, Orthostatic; Kidney; Male; Quinidine; Urinary Bladder Neoplasms

2003
Diclofenac-induced peripheral antinociception is associated with ATP-sensitive K+ channels activation.
    Life sciences, 2004, Apr-02, Volume: 74, Issue:20

    Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Hyperalgesia; Indomethacin; Male; Naloxone; Narcotic Antagonists; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Tolbutamide

2004
Peripheral and spinal mechanisms of antinociceptive action of lumiracoxib.
    European journal of pharmacology, 2005, Apr-18, Volume: 513, Issue:1-2

    Topics: Analgesics; Animals; Apamin; Behavior, Animal; Charybdotoxin; Diclofenac; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Glyburide; Guanylate Cyclase; Hindlimb; Injections, Spinal; Injections, Subcutaneous; Methiothepin; Naloxone; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organic Chemicals; Oxadiazoles; Pain; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Scorpion Venoms

2005
Capsaicin-induced, capsazepine-insensitive relaxation of the guinea-pig ileum.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: 4-Aminopyridine; Acetylcholine; Animals; Apamin; Barium; Benzopyrans; Caffeine; Calcitonin Gene-Related Peptide; Calcium; Capsaicin; Charybdotoxin; Diclofenac; Dimethyl Sulfoxide; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Guanethidine; Guinea Pigs; Ileum; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle Relaxation; Muscle, Smooth; Myosin Light Chains; Nitroarginine; Papaverine; Peptide Fragments; Phosphodiesterase Inhibitors; Phosphorylation; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Protein Serine-Threonine Kinases; Pyrazoles; Receptor, Cannabinoid, CB1; rho-Associated Kinases; Tetraethylammonium; Vasodilator Agents

2006
COX-2-dependent and potentially cardioprotective effects of negative inotropic substances released after ischemia.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Adenosine Triphosphate; Animals; Calcium Signaling; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Depression, Chemical; Diastole; Diclofenac; Disease Models, Animal; Glyburide; In Vitro Techniques; Indomethacin; Myocardial Contraction; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Nitrobenzenes; Perfusion; Potassium Channel Blockers; Potassium Channels; Rats; Reperfusion Injury; Research Design; Sulfonamides; Systole; Time Factors

2007
The hydrogen sulphide-releasing derivative of diclofenac protects against ischaemia-reperfusion injury in the isolated rabbit heart.
    British journal of pharmacology, 2008, Volume: 153, Issue:1

    Topics: Animals; Creatine Kinase; Diclofenac; Epoprostenol; Glutathione; Glyburide; Heart; Hydrogen Sulfide; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Sulfides; Thiones; Ventricular Function, Left

2008
Diclofenac exerts local anesthetic-like actions on rat masseter muscle afferent fibers.
    Brain research, 2008, Feb-15, Volume: 1194

    Topics: Analysis of Variance; Anesthetics; Animals; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Female; Glyburide; Hypoglycemic Agents; Lidocaine; Male; Masseter Muscle; Muscle Fibers, Skeletal; Physical Stimulation; Pinacidil; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sensory Thresholds

2008
Pharmacokinetics and pharmacodynamics of diclofenac in the presence and absence of glibenclamide in the rat.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2008, Volume: 11, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Female; Glyburide; Hypoglycemic Agents; Pain; Pain Measurement; Rats; Rats, Wistar

2008
The effect of glibenclamide on acetylcholine and sodium nitroprusside induced vasodilatation in human cutaneous microcirculation.
    Clinical physiology and functional imaging, 2009, Volume: 29, Issue:1

    Topics: Acetylcholine; Cyclooxygenase Inhibitors; Diclofenac; Forearm; Glyburide; Humans; Injections, Intradermal; Iontophoresis; KATP Channels; Laser-Doppler Flowmetry; Male; Microcirculation; Microinjections; Nitroprusside; Potassium Channel Blockers; Regional Blood Flow; Skin; Time Factors; Vasodilation; Vasodilator Agents; Young Adult

2009
Pharmacokinetic of diclofenac in the presence and absence of glibenclamide in the rat.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2009, Volume: 12, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Dose-Response Relationship, Drug; Drug Interactions; Female; Glyburide; Hypoglycemic Agents; KATP Channels; Limit of Detection; Pain; Pain Measurement; Potassium Channel Blockers; Rats; Rats, Wistar

2009
Mild hypothermia decreases the total clearance of glibenclamide after low dose administration in rats.
    Neuroscience letters, 2016, Feb-12, Volume: 614

    Topics: Animals; Body Temperature; Cytochrome P-450 CYP2C9; Diclofenac; Dose-Response Relationship, Drug; Glyburide; Hypothermia, Induced; Male; Neuroprotective Agents; Rats, Sprague-Dawley

2016