glyburide has been researched along with carbamates in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.49) | 18.7374 |
| 1990's | 19 (28.36) | 18.2507 |
| 2000's | 28 (41.79) | 29.6817 |
| 2010's | 18 (26.87) | 24.3611 |
| 2020's | 1 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Camerini-Davalos, RA; Ehrenreich, TH; Oppermann, W; Reddi, AS; Strugatz, LH | 1 |
| Ampudia-Blasco, FJ; Bender, R; Berger, M; Heinemann, L; Heise, T; Schmidt, A; Starke, AA | 1 |
| Kruseman, AC; Menheere, PP; Müller, PG; Nijst, L; Sels, JP; Wolffenbuttel, BH | 1 |
| Dissing, S; Frøkjaer-Jensen, J; Gromada, J; Kofod, H | 1 |
| Brasseur, R; Lins, L; Malaisse, WJ | 1 |
| Kikuchi, M | 1 |
| Grell, W; Mark, M | 1 |
| Fuhlendorff, J; Ladrière, L; Malaisse, WJ; Malaisse-Lagae, F | 2 |
| Brand, CL; Carr, RD; Fuhlendorff, J; Kofod, H; MacKay, P; Rolin, B; Rorsman, P; Shymko, R | 1 |
| Balfour, JA; Faulds, D | 1 |
| Grell, W; Griss, G; Hurnaus, R; Luger, P; Mark, M; Müller, P; Nar, H; Rupprecht, E; Sauter, R; Wittneben, H | 1 |
| Mooradian, AD; Thurman, JE | 1 |
| Landgraf, R; Wolffenbuttel, BH | 1 |
| Clauson, P; Damsbo, P; Marbury, TC; Windfeld, K | 1 |
| Huang, WC; Lebovitz, H; Marbury, T; Strange, P | 1 |
| Bilo, HJ; Landgraf, R; Müller, PG | 1 |
| Kwan, HY; Yao, X | 1 |
| Cai, Z; Lansdell, KA; Sheppard, DN | 1 |
| Dunning, BE; Hu, S; Wang, S | 1 |
| Riddle, M | 1 |
| Bell, PA; Boettcher, BR; Dunning, BE; Fanelli, B; Geisse, S; Hu, S; Schmitz, R; Wang, S | 1 |
| Landgraf, R | 1 |
| Rutten, GE | 1 |
| Hu, S; Wang, S | 1 |
| Hu, S | 1 |
| Cozma, LS; Dunseath, GJ; Langendorg, KW; Luzio, SD; Owens, DR; Pieber, T | 1 |
| Mafauzy, M | 1 |
| Ashcroft, SJ; Mikhailov, MV; Mikhailova, EA | 1 |
| Ambrosi, F; Boemi, M; Carle, F; Filipponi, P; Gregorio, F | 1 |
| Bell, CF; Botteman, MF; Braunstein, SN; Devine, ST; Ramsdell, JW; Stephens, JM | 1 |
| Nicklasson, L; Stockl, K; Vanderplas, AM | 1 |
| Carr, RD; Degn, KB; Gall, MA; Rizza, RA; Schmitz, O; Thomsen, MK; Veldhuis, JD; Østergård, T | 1 |
| Haslbeck, M; Jakob, S; Kellerer, M; Linn, T | 1 |
| Abrahamson, MJ | 1 |
| Corll, C; Martin, RJ; Porter, JR; Roane, DS; Zhang, Y; Zhou, J | 1 |
| Esposito, K; Giugliano, D; Marfella, R; Nappo, F | 1 |
| Bae, JH; Cho, CH; Han, J; Jang, BC; Kim, SP; Kim, SS; Lee, HY; Lim, JG; Park, JW; Park, MJ; Song, DK; Suh, SI; Yun, JE | 1 |
| Berney, T; Bosco, D; Carr, RD; Donath, MY; Maedler, K; Zuellig, RA | 1 |
| Abbatecola, AM; Grella, R; Manzella, D; Paolisso, G | 1 |
| Hjemdahl, P; Ostenson, CG; Wallén, NH; Yngen, M | 1 |
| Choudhury, H; Harisudhan, T; Mullangi, R; Srinivas, NR; Venkatesh, P | 1 |
| Kühner, P; Quast, U; Russ, U; Stephan, D; Winkler, M | 1 |
| Fedele, V; Fioravanti, M; Leotta, C; Paolisso, G; Papa, G; Purrello, F; Rizzo, MR; Solerte, SB | 1 |
| Erkent, U; Ertunc, M; Guc, MO; Ilhan, M; Iskit, AB; Onur, R | 1 |
| Jin, SH; Li, ZR; Shi, YQ; Yao, J | 1 |
| Bieger, S; Kühner, P; Quast, U; Stephan, D; Winkler, M; Wolff, F | 1 |
| Gupta, A; Jain, S; Kumar, N; Tiwary, AK | 1 |
| Meneilly, GS | 1 |
| Bain, SC; Bodvarsdottir, TB; Bracken, RM; Deacon, CF; Dunseath, G; Holst, JJ; Lowe, GD; Luzio, S; Prior, SL; Rumley, A; Stephens, JW; Wareham, K | 1 |
| Abdelmoneim, AS; Brocks, DR; Hasenbank, SE; Light, PE; Seubert, JM; Simpson, SH | 1 |
| Bryan, J; Kühner, P; Ortiz, D; Prager, R; Quast, U; Russ, U; Stephan, D; Winkler, M | 1 |
| Amato, S; Baiocco, E; Curione, M; Di Bona, S; Gatti, A; Mandosi, E; Morano, S; Rossetti, M; Salvatore, S; Tarquini, G; Turinese, I; Varrenti, M | 1 |
| Andersson, C; Fosbøl, EL; Gislason, G; Køber, L; Mogensen, UM; Scheller, NM; Schramm, TK; Torp-Pedersen, C; Vaag, A | 1 |
| Abdelmoneim, AS; Huang, Y; Light, P; Qiu, W; Simpson, SH | 1 |
| Benoit-Biancamano, MO; Fortin, JS | 1 |
| Chinwuba Okoye, T; Chukwunonso Obi, B; Nonye Igwe, C; Okpashi, VE; Olisah Alumanah, E | 1 |
| Berggren, PO; Zaitsev, SV; Zaitseva, II | 1 |
| Bilker, WB; Brensinger, CM; Chiang, C; Han, X; Hennessy, S; Leonard, CE; Li, L | 1 |
| Areosa Sastre, A; González-Colaço Harmand, M; Martínez, G; Vernooij, RW | 1 |
| Dehpour, AR; Moradi, A; Nikoui, V; Ostadhadi, S; Zolfaghari, S | 1 |
| Aoyama, S; Fujino, R; Hashizume, K; Ito, K; Lee, W; Maeda, K; Ninomiya, SI; Sugiyama, Y; Toshimoto, K | 1 |
| Bachmann, HS; Besser, M; Koester, V; Severing, AL; Stuermer, EK; Terberger, N | 1 |
| Huang, HK; Yeh, JI | 1 |
| David, LL; Innes, LM; Kandasamy, B; Martin, GM; Shyng, SL; Sung, MW; Yang, Z; Yoshioka, C | 1 |
| Asaumi, R; Imawaka, H; Kusuhara, H; Lee, W; Menzel, K; Nunoya, KI; Sugiyama, Y | 1 |
| Bilker, WB; Brensinger, CM; Flory, JH; Hee Nam, Y; Hennessy, S; Leonard, CE | 1 |
9 review(s) available for glyburide and carbamates
| Article | Year |
|---|---|
Modulation of insulin secretion in non-insulin-dependent diabetes mellitus by two novel oral hypoglycaemic agents, NN623 and A4166.
Topics: Administration, Oral; Biological Availability; Blood Glucose; Carbamates; Cyclohexanes; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Intestinal Absorption; Molecular Structure; Nateglinide; Phenylalanine; Piperidines; Reference Values; Stereoisomerism | 1996 |
Repaglinide.
Topics: Animals; Carbamates; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Islets of Langerhans; Piperidines; Randomized Controlled Trials as Topic; Stereoisomerism | 1998 |
Drug therapy of postprandial hyperglycaemia.
Topics: 1-Deoxynojirimycin; Acarbose; Amyloid; Carbamates; Diabetes Mellitus; Enzyme Inhibitors; Glucosamine; Glyburide; Humans; Hyperglycemia; Hypoglycemic Agents; Imino Pyranoses; Inositol; Insulin; Insulin Lispro; Islet Amyloid Polypeptide; Piperidines; Postprandial Period; Trisaccharides | 1999 |
Combining sulfonylureas and other oral agents.
Topics: Acarbose; Administration, Oral; Carbamates; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemic Agents; Metformin; Piperidines; Sulfonylurea Compounds | 2000 |
Meglitinide analogues in the treatment of type 2 diabetes mellitus.
Topics: Benzamides; Carbamates; Cyclohexanes; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Molecular Structure; Nateglinide; Phenylalanine; Piperidines | 2000 |
[Repaglinide, potentially a therapeutic improvement for diabetes mellitus type 2].
Topics: Carbamates; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Metformin; Piperidines; Therapeutic Equivalency | 2001 |
[Continuation 50. Type 2 diabetes: possibilities and limitations of pharmacological therapy].
Topics: 1-Deoxynojirimycin; Acarbose; Aged; Blood Glucose; Carbamates; Contraindications; Cyclohexanes; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enzyme Inhibitors; Fasting; Follow-Up Studies; Germany; Glucosamine; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemia; Hypoglycemic Agents; Imino Pyranoses; Insulin; Metformin; Middle Aged; Nateglinide; Obesity; Patient Compliance; Phenylalanine; Pioglitazone; Piperidines; Practice Guidelines as Topic; Risk Factors; Rosiglitazone; Sulfonylurea Compounds; Thiazolidinediones; Time Factors | 2003 |
Variations in tissue selectivity amongst insulin secretagogues: a systematic review.
Topics: Animals; ATP-Binding Cassette Transporters; Carbamates; Cardiovascular Diseases; Cricetinae; Cyclohexanes; Diabetes Mellitus, Type 2; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Ischemic Preconditioning, Myocardial; Isoindoles; Mice; Muscle, Smooth, Vascular; Myocytes, Cardiac; Nateglinide; Phenylalanine; Piperidines; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Risk Factors; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide | 2012 |
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia.
Topics: Carbamates; Cause of Death; Cognition Disorders; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Memory Disorders; Metformin; Piperidines; Randomized Controlled Trials as Topic; Rosiglitazone; Thiazolidinediones | 2017 |
17 trial(s) available for glyburide and carbamates
| Article | Year |
|---|---|
Comparative dose-related time-action profiles of glibenclamide and a new non-sulphonylurea drug, AG-EE 623 ZW, during euglycaemic clamp in healthy subjects.
Topics: Administration, Oral; Adult; Blood Glucose; Carbamates; Dose-Response Relationship, Drug; Glucose; Glucose Clamp Technique; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Piperidines; Time Factors | 1994 |
Effects of a new oral hypoglycaemic agent, repaglinide, on metabolic control in sulphonylurea-treated patients with NIDDM.
Topics: Aged; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Female; Fructosamine; Gliclazide; Glyburide; Glycated Hemoglobin; Hexosamines; Humans; Hypoglycemic Agents; Lipids; Male; Middle Aged; Piperidines; Tolbutamide | 1993 |
Modulation of insulin secretion in non-insulin-dependent diabetes mellitus by two novel oral hypoglycaemic agents, NN623 and A4166.
Topics: Administration, Oral; Biological Availability; Blood Glucose; Carbamates; Cyclohexanes; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Intestinal Absorption; Molecular Structure; Nateglinide; Phenylalanine; Piperidines; Reference Values; Stereoisomerism | 1996 |
A 1-year multicenter randomized double-blind comparison of repaglinide and glyburide for the treatment of type 2 diabetes. Dutch and German Repaglinide Study Group.
Topics: Adult; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Double-Blind Method; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Middle Aged; Piperidines | 1999 |
A double-blind randomized comparison of meal-related glycemic control by repaglinide and glyburide in well-controlled type 2 diabetic patients.
Topics: Adult; Aged; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Drug Administration Schedule; Eating; Energy Intake; Fasting; Glyburide; Humans; Hypoglycemic Agents; Middle Aged; Piperidines | 1999 |
Repaglinide versus glyburide: a one-year comparison trial.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Carbamates; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Fibrinogen; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Piperidines; Prospective Studies; Triglycerides; United States; United States Food and Drug Administration | 1999 |
A comparison of repaglinide and glibenclamide in the treatment of type 2 diabetic patients previously treated with sulphonylureas.
Topics: Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Middle Aged; Piperidines; Sulfonylurea Compounds | 1999 |
Comparison of the effects of three insulinotropic drugs on plasma insulin levels after a standard meal.
Topics: Aged; Carbamates; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Eating; Female; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Piperidines | 2002 |
Repaglinide versus glibenclamide treatment of Type 2 diabetes during Ramadan fasting.
Topics: Biomarkers; Carbamates; Diabetes Mellitus, Type 2; Fasting; Feeding Behavior; Female; Fructosamine; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Islam; Malaysia; Male; Middle Aged; Piperidines; Risk Factors; Safety; Time Factors | 2002 |
The insulin secretagogues glibenclamide and repaglinide do not influence growth hormone secretion in humans but stimulate glucagon secretion during profound insulin deficiency.
Topics: Blood Glucose; C-Peptide; Carbamates; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Glucagon; Glucose Clamp Technique; Glyburide; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Piperidines; Placebos; Potassium Channel Blockers; Somatostatin | 2004 |
Regression of carotid atherosclerosis by control of postprandial hyperglycemia in type 2 diabetes mellitus.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Carbamates; Carotid Artery Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fasting; Female; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Inflammation; Insulin; Lipids; Male; Middle Aged; Piperidines; Postprandial Period; Single-Blind Method; Tunica Intima; Tunica Media; Ultrasonography | 2004 |
Repaglinide administration improves brachial reactivity in type 2 diabetic patients.
Topics: Aged; Blood Glucose; Brachial Artery; Carbamates; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Middle Aged; Oxidative Stress; Piperidines | 2005 |
Meal-induced platelet activation in Type 2 diabetes mellitus: effects of treatment with repaglinide and glibenclamide.
Topics: Adenosine Diphosphate; Blood Glucose; C-Reactive Protein; Carbamates; Cross-Over Studies; Diabetes Mellitus, Type 2; Eating; Fasting; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Intercellular Adhesion Molecule-1; Male; Middle Aged; P-Selectin; Piperidines; Platelet Activation; Platelet Function Tests; Postprandial Period; Treatment Outcome; von Willebrand Factor | 2006 |
Safety of type 2 diabetes treatment with repaglinide compared with glibenclamide in elderly people: A randomized, open-label, two-period, cross-over trial.
Topics: Aged; Carbamates; Cross-Over Studies; Diabetes Mellitus, Type 2; Glyburide; Humans; Piperidines | 2006 |
Effect of repaglinide versus glyburide on postprandial glucose and insulin values in elderly patients with type 2 diabetes.
Topics: Aged; Area Under Curve; Blood Glucose; Carbamates; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Insulin; Male; Piperidines; Postprandial Period | 2011 |
Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus.
Topics: Adult; Aged; Analysis of Variance; Biomarkers; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Drug Administration Schedule; Drug Therapy, Combination; E-Selectin; F2-Isoprostanes; Female; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hypoglycemic Agents; Incretins; Insulin; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Metformin; Middle Aged; Oxidative Stress; Piperidines; Postprandial Period; Time Factors; Treatment Outcome; Wales | 2011 |
Lack of the QTc physiologic decrease during cardiac stress test in patients with type 2 diabetes treated with secretagogues.
Topics: Aged; Arrhythmias, Cardiac; Carbamates; Diabetes Mellitus, Type 2; Electrocardiography; Exercise Test; Female; Glyburide; Heart Rate; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Piperidines | 2014 |
42 other study(ies) available for glyburide and carbamates
| Article | Year |
|---|---|
Diabetic glomerulosclerosis in KK mice and its prevention by glyburide and pyridinolcarbamate.
Topics: Animals; Blood Glucose; Carbamates; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glucose Tolerance Test; Glyburide; Kidney; Mice; Mice, Inbred Strains; Pyridinolcarbamate; Species Specificity | 1979 |
Effects of the hypoglycaemic drugs repaglinide and glibenclamide on ATP-sensitive potassium-channels and cytosolic calcium levels in beta TC3 cells and rat pancreatic beta cells.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Calcium; Carbamates; Cell Line; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Glyburide; Hypoglycemic Agents; Ion Channel Gating; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Patch-Clamp Techniques; Piperidines; Potassium Channels; Rats; Serum Albumin; Time Factors; Verapamil | 1995 |
Conformational analysis of non-sulfonylurea hypoglycemic agents of the meglitinide family.
Topics: Benzamides; Carbamates; Cyclohexanes; Drug Design; Glyburide; Hypoglycemic Agents; Indoles; Isoindoles; Molecular Conformation; Nateglinide; Phenylalanine; Piperidines; Stereoisomerism; Structure-Activity Relationship; Sulfonylurea Compounds | 1995 |
Hypoglycaemic effects of the novel antidiabetic agent repaglinide in rats and dogs.
Topics: Animals; Carbamates; Dogs; Female; Glyburide; Hypoglycemic Agents; Piperidines; Rats; Rats, Wistar; Stereoisomerism; Sulfonylurea Compounds | 1997 |
Repaglinide, glibenclamide and glimepiride administration to normal and hereditarily diabetic rats.
Topics: Administration, Oral; Animals; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Fasting; Female; Glyburide; Hypoglycemic Agents; Insulin; Male; Piperidines; Rats; Rats, Wistar; Sulfonylurea Compounds | 1997 |
Effect of antidiabetic agents on the increase in glycemia and insulinemia caused by refeeding in hereditarily diabetic rats.
Topics: Animals; Blood Glucose; Carbamates; Diabetes Mellitus, Experimental; Food; Glyburide; Hypoglycemic Agents; Insulin; Male; Piperidines; Rats; Starvation | 1997 |
Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes.
Topics: Animals; Binding Sites; Binding, Competitive; Blood Glucose; Carbamates; Cohort Studies; Culture Techniques; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Evoked Potentials; Glucose; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Osmolar Concentration; Patch-Clamp Techniques; Perfusion; Piperidines; Rats; Rats, Sprague-Dawley; Time Factors; Tritium | 1998 |
Repaglinide and related hypoglycemic benzoic acid derivatives.
Topics: Administration, Oral; Animals; ATP-Binding Cassette Transporters; Benzoates; Blood Glucose; Carbamates; Crystallography, X-Ray; Female; Glyburide; Hypoglycemic Agents; Models, Molecular; Molecular Conformation; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship; Sulfonylurea Compounds; Sulfonylurea Receptors | 1998 |
Activity of voltage-gated K+ channels is associated with cell proliferation and Ca2+ influx in carcinoma cells of colon cancer.
Topics: 4-Aminopyridine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carbamates; Cell Division; Charybdotoxin; Colonic Neoplasms; Glyburide; Humans; Ion Channel Gating; Nickel; Peptides; Phenylcarbamates; Potassium; Potassium Channel Blockers; Potassium Channels; Quaternary Ammonium Compounds; RNA, Messenger; Tetraethylammonium; Tumor Cells, Cultured | 1999 |
Inhibition of heterologously expressed cystic fibrosis transmembrane conductance regulator Cl- channels by non-sulphonylurea hypoglycaemic agents.
Topics: Adenosine Triphosphate; Animals; Benzamides; Carbamates; Cell Line; Chloride Channels; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Electric Conductivity; Epithelial Cells; Glyburide; Humans; Hypoglycemic Agents; Indoles; Ion Channel Gating; Isoindoles; Kinetics; Mice; Patch-Clamp Techniques; Piperidines; Sulfonylurea Compounds; Transfection | 1999 |
Tissue selectivity of antidiabetic agent nateglinide: study on cardiovascular and beta-cell K(ATP) channels.
Topics: Animals; Aorta, Thoracic; Carbamates; Cardiovascular System; Coronary Vessels; Cyclohexanes; Glyburide; Heart; Hypoglycemic Agents; Islets of Langerhans; Male; Muscle, Smooth, Vascular; Nateglinide; Phenylalanine; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Swine | 1999 |
Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide.
Topics: Animals; ATP-Binding Cassette Transporters; Binding, Competitive; Carbamates; Cell Membrane; Cell Separation; Cells, Cultured; Cyclohexanes; Glucose; Glyburide; Glycosyltransferases; Humans; Hypoglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin; Islets of Langerhans; KATP Channels; Kinetics; Male; Membrane Proteins; Nateglinide; Patch-Clamp Techniques; Phenylalanine; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sulfonylurea Compounds | 2000 |
Effect of insulinotropic agent nateglinide on Kv and Ca(2+) channels in pancreatic beta-cell.
Topics: Animals; Calcium Channels; Carbamates; Cyclohexanes; Dose-Response Relationship, Drug; Electric Stimulation; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Potentials; Nateglinide; Patch-Clamp Techniques; Phenylalanine; Piperidines; Potassium Channels; Rats; Rats, Sprague-Dawley | 2001 |
Interaction of nateglinide with K(ATP) channel in beta-cells underlies its unique insulinotropic action.
Topics: Adenosine Triphosphate; Animals; Carbamates; Cyclohexanes; Dose-Response Relationship, Drug; Glucose; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Membrane Potentials; Nateglinide; Phenylalanine; Piperidines; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Sulfonylurea Compounds; Time Factors | 2002 |
A novel simple method for the investigation of drug binding to the K(ATP) channel sulfonylurea receptor.
Topics: Animals; ATP-Binding Cassette Transporters; Carbamates; Gliclazide; Glyburide; Hypoglycemic Agents; Kinetics; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Rats; Receptors, Drug; Spodoptera; Sulfonylurea Receptors; Tolbutamide | 2002 |
Effects of S 21403 on hormone secretion from isolated rat pancreas at different glucose concentrations.
Topics: Animals; Carbamates; Dose-Response Relationship, Drug; Glucose; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Indoles; Insulin; Insulin Secretion; Isoindoles; Male; Pancreas; Piperidines; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Economic model of first-line drug strategies to achieve recommended glycaemic control in newly diagnosed type 2 diabetes mellitus.
Topics: Carbamates; Cohort Studies; Decision Trees; Diabetes Mellitus, Type 2; Direct Service Costs; Drug Costs; Drug Therapy, Combination; Glipizide; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Managed Care Programs; Markov Chains; Metformin; Models, Economic; Piperidines; Rosiglitazone; Thiazoles; Thiazolidinediones; United States | 2003 |
A comparison of costs for four oral antidiabetic regimens within a managed care population.
Topics: Administration, Oral; Adolescent; Adult; Aged; California; Carbamates; Cohort Studies; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Health Care Costs; Humans; Hypoglycemic Agents; Insulin; Insurance Claim Review; Male; Managed Care Programs; Metformin; Middle Aged; Piperidines; Retrospective Studies | 2003 |
Optimal glycemic control in type 2 diabetes mellitus: fasting and postprandial glucose in context.
Topics: Antihypertensive Agents; Blood Glucose; Blood Glucose Self-Monitoring; Carbamates; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Progression; Drug Therapy, Combination; Glyburide; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Metformin; Piperidines; Postprandial Period | 2004 |
Evidence for hypothalamic K+(ATP) channels in the modulation of glucose homeostasis.
Topics: Animals; Blood Glucose; Carbamates; Chromatography, High Pressure Liquid; Epinephrine; Glucagon; Glyburide; Homeostasis; Hypoglycemic Agents; Hypothalamus; Male; Norepinephrine; Piperidines; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley | 2004 |
Taurine block of cloned ATP-sensitive K+ channels with different sulfonylurea receptor subunits expressed in Xenopus laevis oocytes.
Topics: Animals; ATP-Binding Cassette Transporters; Carbamates; Drug Interactions; Female; Gene Expression; Gliclazide; Glyburide; Hypoglycemic Agents; Membrane Proteins; Mice; Oocytes; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Subunits; Rats; Receptors, Drug; Sulfonylurea Receptors; Taurine; Tolbutamide; Xenopus laevis | 2004 |
Sulfonylurea induced beta-cell apoptosis in cultured human islets.
Topics: Adult; Aged; Apoptosis; Calcium; Carbamates; Cells, Cultured; Cyclohexanes; Dose-Response Relationship, Drug; Glyburide; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Middle Aged; Nateglinide; Phenylalanine; Piperidines | 2005 |
Simultaneous estimation of six anti-diabetic drugs--glibenclamide, gliclazide, glipizide, pioglitazone, repaglinide and rosiglitazone: development of a novel HPLC method for use in the analysis of pharmaceutical formulations and its application to human p
Topics: Carbamates; Chromatography, High Pressure Liquid; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Molecular Structure; Pioglitazone; Piperidines; Reproducibility of Results; Rosiglitazone; Thiazolidinediones | 2006 |
Selectivity of repaglinide and glibenclamide for the pancreatic over the cardiovascular K(ATP) channels.
Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Binding, Competitive; Carbamates; Cardiovascular System; Cell Line; Dose-Response Relationship, Drug; Glyburide; Humans; Hypoglycemic Agents; Membrane Potentials; Molecular Structure; Pancreas; Patch-Clamp Techniques; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors | 2006 |
Glibenclamide attenuates the antiarrhythmic effect of endotoxin with a mechanism not involving K(ATP) channels.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbamates; Cyclohexanes; Disease Models, Animal; Drug Interactions; Endotoxemia; Glyburide; Heart Atria; Heart Conduction System; Lipopolysaccharides; Male; Myocardial Ischemia; Nateglinide; Phenylalanine; Piperidines; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Tachycardia, Ventricular; Tetraethylammonium; Time Factors; Ventricular Fibrillation; Ventricular Premature Complexes | 2007 |
Development of a RP-HPLC method for screening potentially counterfeit anti-diabetic drugs.
Topics: Carbamates; Chromatography, High Pressure Liquid; Gliclazide; Glipizide; Glyburide; Hypoglycemic Agents; Molecular Structure; Piperidines; Reproducibility of Results; Sulfonylurea Compounds | 2007 |
Testing the bipartite model of the sulfonylurea receptor binding site: binding of A-, B-, and A + B-site ligands.
Topics: Amino Acid Substitution; Animals; ATP-Binding Cassette Transporters; Binding Sites; Binding, Competitive; Carbamates; Cell Line; Cyclohexanes; Dose-Response Relationship, Drug; Glyburide; Hypoglycemic Agents; KATP Channels; Ligands; Mice; Molecular Structure; Nateglinide; Phenylalanine; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Radioligand Assay; Rats; Receptors, Drug; Sulfonylurea Compounds; Sulfonylurea Receptors; Transfection | 2007 |
Spermicidal activity of sulfonylureas and meglitinide analogues: role of intrasperm Ca2+ elevation.
Topics: Adult; Benzamides; Calcium; Carbamates; Cross-Over Studies; Dose-Response Relationship, Drug; Gliclazide; Glyburide; Homeostasis; Humans; Hypoglycemic Agents; KATP Channels; Male; Piperidines; Sperm Motility; Spermatocidal Agents; Spermatozoa; Sulfonylurea Compounds; Time Factors | 2008 |
Importance of the Kir6.2 N-terminus for the interaction of glibenclamide and repaglinide with the pancreatic K(ATP) channel.
Topics: Animals; ATP-Binding Cassette Transporters; Binding Sites; Carbamates; Glyburide; HEK293 Cells; Humans; Hypoglycemic Agents; Pancreas; Patch-Clamp Techniques; Piperidines; Potassium Channels, Inwardly Rectifying; Protein Binding; Rats; Receptors, Drug; Sulfonylurea Receptors | 2012 |
Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study.
Topics: Aged; Carbamates; Cardiovascular Diseases; Denmark; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Morbidity; Myocardial Infarction; Piperidines; Registries; Retrospective Studies; Risk Factors; Stroke; Sulfonylurea Compounds; Tolbutamide | 2015 |
Comparative cardiovascular safety of insulin secretagogues following hospitalization for ischemic heart disease among type 2 diabetes patients: a cohort study.
Topics: Aged; Aged, 80 and over; Alberta; Blue Cross Blue Shield Insurance Plans; Carbamates; Cardiovascular Diseases; Cohort Studies; Databases, Factual; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Female; Gliclazide; Glyburide; Hospitalization; Humans; Hypoglycemic Agents; Male; Myocardial Ischemia; Piperidines; Proportional Hazards Models; Retrospective Studies; Risk; Universal Health Insurance | 2015 |
In vitro evaluation of hypoglycemic agents to target human islet amyloid polypeptide: a key protein involved in amyloid deposition and beta-cell loss.
Topics: Amyloid; Amyloidosis; Animals; Carbamates; Cell Survival; Chromans; Circular Dichroism; Glyburide; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Piperidines; Protein Structure, Secondary; Rats; Thiazolidinediones; Troglitazone | 2015 |
Comparative Study of the Antioxidant Effects of Metformin, Glibenclamide, and Repaglinide in Alloxan-Induced Diabetic Rats.
Topics: Alloxan; Animals; Antioxidants; Biomarkers; Blood Glucose; Carbamates; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Glutathione; Glyburide; Hypoglycemic Agents; Lipid Peroxidation; Male; Malondialdehyde; Metformin; Oxidative Stress; Piperidines; Rats; Superoxide Dismutase | 2016 |
Insulinotropic compounds decrease endothelial cell survival.
Topics: Benzofurans; Carbamates; Cell Proliferation; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Glucose; Glyburide; Human Umbilical Vein Endothelial Cells; Humans; Hypoglycemic Agents; Imidazoles; Indoles; Nitric Oxide; Piperidines; Vascular Endothelial Growth Factor A | 2016 |
Biomedical Informatics Approaches to Identifying Drug-Drug Interactions: Application to Insulin Secretagogues.
Topics: Area Under Curve; Carbamates; Cyclohexanes; Databases, Factual; Diabetes Mellitus, Type 2; Drug Interactions; Glipizide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Medical Informatics; Nateglinide; Pharmacoepidemiology; Phenylalanine; Piperidines; Sulfonylurea Compounds | 2017 |
Cromakalim, a Potassium Channel Opener, Ameliorates the Organophosphate and Carbamate-Induced Seizure in Mice.
Topics: Animals; Anticonvulsants; Carbamates; Cromakalim; Dichlorvos; Dose-Response Relationship, Drug; Glyburide; Male; Mice; Organophosphate Poisoning; Physostigmine; Potassium Channels; Seizures | 2018 |
Strategies to improve the prediction accuracy of hepatic intrinsic clearance of three antidiabetic drugs: Application of the extended clearance concept and consideration of the effect of albumin on CYP2C metabolism and OATP1B-mediated hepatic uptake.
Topics: Albumins; Carbamates; Cytochrome P-450 Enzyme System; Glyburide; HEK293 Cells; Hepatocytes; Humans; Hypoglycemic Agents; Liver; Liver-Specific Organic Anion Transporter 1; Metabolic Clearance Rate; Microsomes, Liver; Models, Biological; Nateglinide; Piperidines; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2018 |
Side effects of frequently used oral antidiabetics on wound healing in vitro.
Topics: Administration, Oral; Apoptosis; Carbamates; Caspases; Cell Line; Endopeptidases; Fibroblasts; Gelatinases; Glyburide; Humans; Hypoglycemic Agents; Keratinocytes; Membrane Proteins; Metformin; Piperidines; Receptors, CXCR4; Serine Endopeptidases; Sitagliptin Phosphate; Wound Healing | 2019 |
Comparison of mortality and cardiovascular event risk associated with various insulin secretagogues: A nationwide real-world analysis.
Topics: Aged; Carbamates; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Follow-Up Studies; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Middle Aged; Mortality; Piperidines; Secretagogues; Sulfonylurea Compounds; Taiwan | 2019 |
Mechanism of pharmacochaperoning in a mammalian K
Topics: Animals; Binding Sites; Carbamates; Cell Line; Cricetinae; Cryoelectron Microscopy; Cysteine; Glyburide; Humans; KATP Channels; Mammals; Models, Molecular; Mutation; Pharmaceutical Preparations; Piperidines; Potassium Channels, Inwardly Rectifying; Protein Binding; Rats | 2019 |
Expanded Physiologically-Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction.
Topics: Biomarkers; Carbamates; Computer Simulation; Coproporphyrins; Drug Interactions; Glyburide; Humans; Models, Biological; Organic Anion Transporters; Piperidines; Rifampin | 2019 |
Angiotensin-Converting Enzyme Inhibitors Used Concomitantly with Insulin Secretagogues and the Risk of Serious Hypoglycemia.
Topics: Administrative Claims, Healthcare; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Carbamates; Databases, Factual; Diabetes Mellitus, Type 2; Drug Interactions; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Male; Medicaid; Metformin; Middle Aged; Nateglinide; Pharmacoepidemiology; Piperidines; Secretagogues; Sulfonylurea Compounds; United States | 2022 |