Compounds > glutathione disulfide
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glutathione disulfide and nov 002

glutathione disulfide has been researched along with nov 002 in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Findlay, VL; Tew, KD; Townsend, DM1
Antonov, VG; Burova, EB; Nikol'skiĭ, NN; Vasilenko, KP1
Garrett, TE; He, L; Hutchens, S; Pazoles, CJ; Tew, KD; Townsend, DM1
Pazoles, CJ; Tew, KD; Townsend, DM1
Antonov, VG; Krutestkaia, ZI; Kurilova, LS; Lebedev, OE1
Tew, KD; Townsend, DM1
Garrett, T; Jenderny, S; Lin, H; Tew, KD; Townsend, DM1
Devane, LC; Garret, TE; He, L; Manevich, Y; Pazoles, CJ; Tew, KD; Townsend, DM; Uys, JD1
Antonov, VG; Butov, SN; Krutetskaia, ZI; Lebedev, OE; Mel'nitskaia, AV1
Avisar, E; Deutsch, YE; Diaz-Montero, CM; Garret-Mayer, E; Glück, S; Hurley, J; Jorda, M; Koniaris, LG; Montero, AJ; Pegram, MD; Rumboldt, T; Schuhwerk, K; Seo, P; Silva, O; Slingerland, J; Welsh, C; Yasir, S1
Diaz-Montero, CM; Feng, W; Montero, AJ; Pazoles, CJ; Shao, L; Wang, Y; Zhou, D; Zidan, AA1
Coker, WJ; Grek, CL; Manevich, Y; Pazoles, CJ; Tew, KD; Townsend, DM; Uys, JD1
Beste, C; Saft, C1
Montaser, SA; Salama, SF1

Reviews

1 review(s) available for glutathione disulfide and nov 002

ArticleYear
Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets.
    Methods in enzymology, 2005, Volume: 401

    Topics: 4-Aminobenzoic Acid; Animals; Antineoplastic Agents; Azo Compounds; Cisplatin; Cytotoxins; Drug Combinations; Glutathione; Glutathione Disulfide; Glutathione Transferase; Humans; Molecular Structure; Neoplasms; Oxidative Stress; para-Aminobenzoates; Prodrugs; Protein Kinases; Signal Transduction

2005

Trials

1 trial(s) available for glutathione disulfide and nov 002

ArticleYear
Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer.
    Breast cancer research and treatment, 2012, Volume: 132, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Disease-Free Survival; Docetaxel; Doxorubicin; Drug Combinations; Female; Glutathione Disulfide; Humans; Immunity, Cellular; Kaplan-Meier Estimate; Mastectomy; Middle Aged; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Staging; Receptor, ErbB-2; Taxoids; Treatment Outcome; Young Adult

2012

Other Studies

12 other study(ies) available for glutathione disulfide and nov 002

ArticleYear
[Oxidized glutathione induces activation of the epidermal growth factor receptor and MAP kinases ERK 1,2].
    Tsitologiia, 2006, Volume: 48, Issue:6

    Topics: Animals; Cell Line, Tumor; Enzyme Activation; ErbB Receptors; Glutathione Disulfide; Humans; Mice; Mitogen-Activated Protein Kinase 1; NIH 3T3 Cells; Oligopeptides; Quinazolines; Transcriptional Activation; Tyrphostins

2006
NOV-002, a glutathione disulfide mimetic, as a modulator of cellular redox balance.
    Cancer research, 2008, Apr-15, Volume: 68, Issue:8

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Physiological Phenomena; Cell Survival; Cisplatin; Drug Combinations; Glutathione; Glutathione Disulfide; Humans; Lung Neoplasms; Oxidation-Reduction

2008
NOV-002, a mimetic of glutathione disulfide.
    Expert opinion on investigational drugs, 2008, Volume: 17, Issue:7

    Topics: Animals; Cisplatin; Drug Combinations; Drug Tolerance; Glutathione Disulfide; Humans; Molecular Mimicry; Molecular Structure

2008
[The effect of oxidized glutathione and its pharmacological analogue, glutoxim, on intracellular Ca2+ concentration in macrophages].
    Tsitologiia, 2008, Volume: 50, Issue:5

    Topics: Animals; Calcium; Cells, Cultured; Cytoplasm; Glutathione Disulfide; Macrophages, Peritoneal; Oligopeptides; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Signal Transduction

2008
Pharmacology of a mimetic of glutathione disulfide, NOV-002.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cisplatin; Clinical Trials as Topic; Drug Combinations; Glutathione Disulfide; Humans; Lung Neoplasms; Oxidation-Reduction; Signal Transduction; Survival Rate

2009
Protective effects of a glutathione disulfide mimetic (NOV-002) against cisplatin induced kidney toxicity.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:1

    Topics: Animals; Antineoplastic Agents; Cisplatin; Creatinine; Drug Combinations; Female; gamma-Glutamyltransferase; Glutathione Disulfide; Kidney Diseases; Kidney Tubules, Proximal; Mice; Mice, Inbred C57BL

2010
Preclinical pharmacokinetic analysis of NOV-002, a glutathione disulfide mimetic.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:7

    Topics: Animals; Cisplatin; Drug Combinations; Glutathione; Glutathione Disulfide; Glutathione Reductase; Mice; Mice, Inbred C57BL; Nonlinear Dynamics; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds; Tissue Distribution

2010
[The involvement of tyrosine kinases and phosphatidylinositol kinases in the effect of oxidized glutathione and glutoxim on Na+ transport in frog skin].
    Tsitologiia, 2010, Volume: 52, Issue:4

    Topics: Androstadienes; Animals; Chromones; Genistein; Glutathione Disulfide; Ion Transport; Male; Minor Histocompatibility Antigens; Morpholines; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rana temporaria; Skin; Sodium; Wortmannin

2010
The glutathione disulfide mimetic NOV-002 inhibits cyclophosphamide-induced hematopoietic and immune suppression by reducing oxidative stress.
    Free radical biology & medicine, 2012, May-01, Volume: 52, Issue:9

    Topics: Animals; Base Sequence; Bone Marrow Cells; Cisplatin; Cyclophosphamide; DNA Primers; Drug Combinations; Flow Cytometry; Glutathione Disulfide; Glutathione Peroxidase; Hematopoiesis; Immune System; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Superoxide Dismutase

2012
S-glutathionylated serine proteinase inhibitors as plasma biomarkers in assessing response to redox-modulating drugs.
    Cancer research, 2012, May-01, Volume: 72, Issue:9

    Topics: alpha 1-Antichymotrypsin; alpha 1-Antitrypsin; Animals; Biomarkers, Tumor; Cisplatin; Dose-Response Relationship, Drug; Drug Combinations; Glutathione; Glutathione Disulfide; Humans; Immunoprecipitation; Mice; Neoplasms; Oxidation-Reduction; Serpins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry

2012
Action selection in a possible model of striatal medium spiny neuron dysfunction: behavioral and EEG data in a patient with benign hereditary chorea.
    Brain structure & function, 2015, Volume: 220, Issue:1

    Topics: Acoustic Stimulation; Adult; Brain Mapping; Case-Control Studies; Chorea; Cisplatin; Computer Simulation; Corpus Striatum; Drug Combinations; Electroencephalography; Evoked Potentials; Glutathione Disulfide; Humans; Models, Neurological; Neurons; Photic Stimulation; Reaction Time; Time Factors; Young Adult

2015
Possible modulating impact of glutathione disulfide mimetic on physiological changes in irradiated rats.
    Human & experimental toxicology, 2015, Volume: 34, Issue:4

    Topics: Animals; Cell Count; Cisplatin; DNA Fragmentation; Drug Combinations; Gamma Rays; Glutathione Disulfide; Hematocrit; Hemoglobins; Male; Oxidative Stress; Radiation-Protective Agents; Rats; Spleen; Whole-Body Irradiation

2015