glutamine has been researched along with pyruvic acid in 213 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 59 (27.70) | 18.7374 |
| 1990's | 40 (18.78) | 18.2507 |
| 2000's | 47 (22.07) | 29.6817 |
| 2010's | 56 (26.29) | 24.3611 |
| 2020's | 11 (5.16) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Betteridge, KJ; Loskutoff, NM; Rieger, D | 1 |
| Downs, SM; Fagbohun, CF | 1 |
| Greene, LW; Wu, G | 1 |
| Borth, N; Katinger, H; Reiter, M; Steindl, F; Weigang, F | 1 |
| Butterworth, RF; Qureshi, IA; Ratnakumari, L | 1 |
| Grill, V; Jalkanen, P; Ostenson, CG; Sako, Y | 1 |
| Field, CJ; Marliss, EB; Wu, GY | 2 |
| Bavister, BD; McKiernan, SH; Tasca, RJ | 1 |
| Almond, MK; Cohen, RD; Flynn, G; Iles, RA; Smith, A | 1 |
| Ardawi, MS; Kateilah, SM; Majzoub, MF; Newsholme, EA | 1 |
| Kenney, R; Parrish, A; Tomacelli, C; Zikira, M | 1 |
| Dumdey, R; Holzhütter, HG; Müller, M; Rathmann, J | 1 |
| Nissim, I; States, B | 1 |
| Matsuno, T | 2 |
| Baverel, G; Martin, G; Michoudet, C | 1 |
| Eizirik, DL; Sandler, S | 1 |
| González, A; Olamendi, J; Rodríguez, L; Soberón, M | 1 |
| Fischer, B; Holm, E; Jacob, S | 1 |
| Lin, S; Raabe, W | 1 |
| Mercer, JR; Silva, SV | 1 |
| Laycock, M; McInnes, AG; Shapiro, S; Vining, LC; Walter, JA | 1 |
| Allignet, E; Junco, E; Lemieux, C; Lemieux, G; Perez, R | 1 |
| Evered, DF; Masola, B; Peters, TJ | 1 |
| Chomatas, H; Iakovou, D; Linardou, A; Palaiologos, G; Philippidis, H | 1 |
| Grunewald, RW; Jans, AW; Kinne, RK | 1 |
| Thompson, JR; Wu, GY | 1 |
| Carpinelli, AR; Dufrane, SP; Garcia-Morales, P; Malaisse, WJ; Malaisse-Lagae, F; Mathias, PC; Sener, A; Valverde, I | 1 |
| Grootegoed, JA; Jansen, R; Oonk, RB; van der Molen, HJ | 1 |
| Chin, NW; Hitti, IF; Lanks, KW | 1 |
| Brunengraber, H; David, F; Garneau, M; Huot, S; Marsolais, C | 1 |
| González, A; Soberón, M | 1 |
| Guay, P; Rieger, D | 1 |
| Lanks, KW | 2 |
| Atkinson, T; Barstow, DA; Chia, WN; Clarke, AR; Holbrook, JJ; Wigley, DB | 1 |
| Gordon, S; Newsholme, EA; Newsholme, P | 1 |
| Gougoux, A; Noel, J; Tejedor, A; Vinay, P; Zizian, L | 1 |
| Aizawa, C; Endou, H; Nakada, J; Yamada, H | 1 |
| Curi, R; Newsholme, EA; Newsholme, P | 1 |
| Erecinska, M; Wilson, DF; Zaleski, J | 1 |
| Mandel, LJ | 1 |
| Ardawi, MS; Crabtree, B; Newsholme, EA | 1 |
| Marchok, AC; Wasilenko, WJ | 2 |
| Duff, DA; Snell, K | 1 |
| Clegg, JS; Gordon, EP | 1 |
| Amos, H; Gomes, MI; Kim, WJ; Lively, MK | 1 |
| Corthay, J; Dunant, Y; Eder, L; Loctin, F | 1 |
| Coleman, PS; Lavietes, BB | 1 |
| Chomatas, H; Iakovou, D; Linardou, A; Palaiologos, G; Philippides, H | 1 |
| Baverel, G; Martin, G | 1 |
| Häussinger, D; Sies, H | 1 |
| Caldecourt, MA; Palmer, TN; Sugden, MC; Warner, JP | 1 |
| Amos, H; Hochstadt, B; Sens, DA | 1 |
| Aultman, KS; Mapes, JP | 1 |
| Langer, J; Lenzen, S; Panten, U; Zielmann, S; Zünkler, BJ | 1 |
| Dufrane, SP; Malaisse, WJ; Malaisse-Lagae, F; Sener, A | 1 |
| Angielski, S; Rybczyńska, A; Stepiński, J | 1 |
| Chen, KS; Lardy, HA | 1 |
| McKeehan, WL | 1 |
| Christophe, J; Hutton, JC; Malaisse, WJ; Malaisse-Legae, F; Sener, A | 1 |
| Malaisse, WJ; Malaisse-Lagae, F; Sener, A | 1 |
| Kodama, H; Maki, I; Nose, O; Okada, S; Sano, T; Tajiri, H; Yabuuchi, H | 1 |
| Kunin, AS; Tannen, RL | 1 |
| Gill, GN; Hornsby, PJ | 1 |
| Baverel, G; Forissier, M | 1 |
| Behar, KL; Gruetter, R; Mason, GF; Novotny, EJ; Rothman, DL; Shulman, RG | 1 |
| Katz, J; Lee, WN; Wals, P | 1 |
| Erecińska, M; Nelson, D | 1 |
| Bernard, F; Blachier, F; Darcy-Vrillon, B; Duée, PH; Meslin, JC; Morel, MT; Posho, L | 1 |
| Friedman, S; Gao, JP; Lanks, KW | 1 |
| Bond, JA; Calder, PC; Curi, R; Newsholme, EA | 1 |
| Curi, R; Newsholme, EA; Parry-Billings, M; Serrano, MA; Williams, JF | 1 |
| Brackett, BG; Zuelke, KA | 1 |
| Huang, X; McKenna, MC; Sonnewald, U; Stevenson, J; Zielke, HR | 1 |
| Hazen, SA; LaNoue, KF; Lynch, CJ; Sly, WS; Waheed, A | 1 |
| Dwarte, D; Evans, G; Maxwell, WM; O'Brien, JK; Ryan, JP | 1 |
| Bachelard, HS; Jones, P; Schousboe, A; Sonnewald, U; Taylor, A; Westergaard, N | 1 |
| Brosnan, JT; Nissim, I; Yudkoff, M | 1 |
| Huang, X; McKenna, MC; Stevenson, JH; Tildon, JT | 1 |
| Dickson, AJ; Murray, K | 1 |
| Bavister, BD; Kito, S | 1 |
| Berkich, DA; Gamberino, WC; LaNoue, KF; Lynch, CJ; Xu, B | 1 |
| Devreker, F; Hardy, K; Winston, RM | 1 |
| Aasly, J; Bakken, IJ; Håberg, A; Haraldseth, O; Qu, H; Sande, LM; Sonnewald, U; Unsgård, G; White, LR | 1 |
| Dixon, RM; Griffin, JL; Matthews, PM; Radda, GK; Rae, C | 1 |
| Gardner, DK; Steeves, TE | 1 |
| Bacurau, RF; Costa Rosa, LF; Homem De Bittencourt, PI; Newsholme, P | 1 |
| Alcantara, S; Sanchez, S | 1 |
| Biramane, J; Devreker, F; Englert, Y; Hardy, K; Van den Bergh, M; Winston, RL | 1 |
| Amado, CB; Bracht, A; Fedatto Júnior, Z; Ishii-Iwamoto, EL; Kelmer-Bracht, AM; Panerari, AD; Vicentini, GE | 1 |
| Constantin-Teodosiu, D; Greenhaff, PL | 1 |
| Moreno-Sánchez, R; Rodríguez-Enríquez, S; Torres-Márquez, ME | 1 |
| Harano, M; Kawada, N; Ryozo, N; Takakura, N; Tanaka, N; Tsuge, H | 1 |
| O'Regan, MH; Phillis, JW; Ren, J | 1 |
| Gil, M; Kaye, PL; Pantaleon, M; Ryan, JP | 1 |
| Leibfritz, D; Richter-Landsberg, C; Zwingmann, C | 1 |
| Akimoto, LS; Bazotte, RB; Lopes, G; Pedrinho, SR | 1 |
| Gabel, SA; London, RE | 1 |
| Bazotte, RB; Borba-Murad, GR; Ceddia, RB; Curi, R; de Souza, HM; Vardanega-Peicher, M | 1 |
| Jordan, F; Sergienko, EA | 1 |
| Larsson, OM; Schousboe, A; Sonnewald, U; Waagepetersen, HS | 1 |
| Gardner, DK; Lane, M | 1 |
| Chan, ST; Ho, PC; Lee, YL; Xu, JS; Yeung, WS | 1 |
| Battaglia, FC; Meschia, G; Narkewicz, MR; Teng, C; Wilkening, RB | 1 |
| Bormann, CL; Clark, SG; Krisher, RL; Swain, JE; Walters, EM; Wheeler, MB | 1 |
| Balcar, VJ; Bubb, WA; Mitrovic, AD; Moussa, Cel-H; Provis, T; Rae, C; Vandenberg, RJ | 1 |
| Ammatuna, M; Battezzati, A; Caumo, A; Coppa, J; Fattorini, A; Luzi, L; Mazzaferro, V; Regalia, E; Romito, R; Sereni, LP | 1 |
| Chadha, PL; Crandall, SC; Qureshi, T; Sumida, KD | 1 |
| Bouzier-Sore, AK; Canioni, P; Merle, M | 1 |
| Bryła, J; Derlacz, RA; Jagielski, AK; Jarzyna, R; Lietz, T; Winiarska, K; Wohner, D | 1 |
| Cohen, DM; Gao, X; Guthrie, PH; Sakai, R; Taegtmeyer, H | 1 |
| McClure, BG; Thompson, SW; Tubman, TR | 1 |
| Bui, BV; Kalloniatis, M; Vingrys, AJ | 1 |
| Aitken, SM; Kirsch, JF | 1 |
| Andrade, ER; Costa, SH; Ferreira, FV; Figueiredo, JR; Lôbo, RN; Nunes, AP; Silva, JR; van den Hurk, R | 1 |
| Cline, GW; Kibbey, RG; Lepine, RL; Papas, KK; Shulman, GI | 1 |
| BARTLETT, PD; GAEBLER, OH | 1 |
| Hertz, L; Kala, G | 2 |
| Bilodeau-Goeseels, S | 1 |
| Basset, G; Hanson, AD; Nichols, BP; Ravanel, S; Rébeillé, F; Sahr, T | 1 |
| Agascioglu, E; Giroix, MH; Malaisse, WJ; Sener, A | 1 |
| Biener, R; Goudar, C; Konstantinov, K; Michaels, J; Piret, J; Zhang, C | 1 |
| Songsasen, N; Spindler, RE; Wildt, DE | 1 |
| Enblad, P; Hesselager, G; Hillered, L; Kumlien, E; Lewén, A; Marklund, N; Nilsson, P; Ronne-Engström, E; Ryttlefors, M; Salci, K; Samuelsson, C; Zetterling, M | 1 |
| Athanasiou, KA; Johns, DE | 1 |
| Baab, PJ; Zielke, CL; Zielke, HR | 1 |
| Alves, PM; Carinhas, N; Oliveira, R; Santos, SS; Teixeira, AP | 1 |
| Bjerring, PN; Frederiksen, HJ; Hansen, BA; Hauerberg, J; Jorgensen, L; Larsen, FS; Tofteng, F | 1 |
| Seah, SY; Wang, W | 1 |
| Bazotte, RB; Curi, R; Felisberto-Junior, AM; Garcia, RF; Oliveira-Yamashita, F | 1 |
| Baldwin, RL; Bequette, BJ; El-Kadi, SW; McLeod, KR; Sunny, NE | 1 |
| Cline, GW; Kibbey, RG; Kirkpatrick, CL; Pongratz, RL; Pontoglio, M; Shulman, GI; Wollheim, CB; Yaniv, M; Zhao, X | 1 |
| Bresolin, N; Brighina, E; Pardi, G; Rango, M | 1 |
| Cappelli, D; Chu, L; Dong, Z; Lai, Y; Song, L; Su, J; Xu, X | 1 |
| Enblad, P; Hillered, L; Howells, T; Kumlien, E; Ronne-Engström, E; Samuelsson, C | 1 |
| Babu, CS; Ramanathan, M | 1 |
| Barosa, C; Delgado, TC; Diogo, L; Garcia, P; Jones, JG | 1 |
| Acosta, ML; Bui, BV; Donaldson, P; Hu, RG; Kalloniatis, M; Vingrys, AJ | 1 |
| Alwine, JC; Chambers, JW; Maguire, TG | 1 |
| Chen, PM; Chen, YY; Chia, JS; Lai, CH; Sher, S; Yu, SL | 1 |
| GONCALVES, JM; GREENSTEIN, JP | 1 |
| GREENSTEIN, JP; PRICE, VE | 1 |
| ERRERA, M; GONCALVES, JM; GREENSTEIN, JP | 1 |
| Bellance, N; Benard, G; Ježek, P; Plecitá-Hlavatá, L; Rossignol, R; Smolková, K | 1 |
| Cerdan, S; Contreras, L; Garzón, M; Kobayashi, K; Llorente-Folch, I; Pardo, B; Rodrigues, TB; Saheki, T; Satrústegui, J | 1 |
| Isaev, NK; Novikova, SV; Stelmashook, EV | 1 |
| Heinzle, E; Niklas, J; Noll, T; Sandig, V; Schräder, E | 1 |
| Alves, PM; Amaral, AI; Sonnewald, U; Teixeira, AP | 1 |
| Cheng, T; DeBerardinis, RJ; Jin, ES; Matés, JM; Mullen, AR; Sudderth, J; Yang, C | 1 |
| Dafni, H; Ronen, SM | 1 |
| Alwine, JC; Clippinger, AJ; Pierciey, FJ; Yu, Y | 1 |
| Barrett, P; Bolborea, M; Campbell, G; Ebling, FJ; Herwig, A; Mayer, CD; Morgan, PJ; Nilaweera, K | 1 |
| Heinzle, E; Niklas, J; Priesnitz, C; Rose, T; Sandig, V | 1 |
| Li, J; Logothetis, N; Rauch, A; von Pföstl, V; Zaldivar, D; Zhang, X | 1 |
| Brown, PM; Crockett, JC; Hutchison, JD | 1 |
| Heinzle, E; Niklas, J; Noor, F; Strigun, A; Wahrheit, J | 1 |
| Baverel, G; El Hage, M; Ferrier, B; Martin, G | 1 |
| Carpenter, JW; Songsasen, N; Wesselowski, S; Wildt, DE | 1 |
| Bjerring, PN; Clemmesen, JO; Frederiksen, HJ; Hauerberg, J; Larsen, FS; Nielsen, HB | 1 |
| Good, LB; Ma, Q; Malloy, CR; Marin-Valencia, I; Pascual, JM | 1 |
| Behbahan, IS; Christofk, HR; Ferrari, R; Hong, CS; Huang, TW; Kurdistani, SK; Li, K; McBrian, MA; Seligson, DB; Su, T; Vogelauer, M | 1 |
| Allen, BG; Bouchard, B; Chatham, JC; Des Rosiers, C; Dolinsky, VW; Dyck, JR; Gélinas, R; Labarthe, F; Lauzier, B; Merlen, C; Rivard, ME; Vaillant, F | 1 |
| Bazotte, RB; Borba-Murad, GR; da Rocha, AF; de Fatima Silva, F; de Souza, CO; de Souza, HM; Liboni, TF; Miksza, DR; Moreira, CC | 1 |
| Coe, CL; Ennis, K; Georgieff, MK; Lubach, GR; Oz, G; Rao, R | 1 |
| Brekke, E; Brubakk, AM; Håberg, A; Morken, TS; Sonnewald, U; Widerøe, M | 1 |
| Good, LB; Henry, PG; Jeffrey, FM; Malloy, CR; Marin-Valencia, I; Pascual, JM; Shestov, AA | 1 |
| Koblihova, E; Laszikova, E; Pantoflicek, T; Prazak, J; Ryska, M; Ryska, O | 1 |
| Dmitriev, RI; Golubeva, AV; Papkovsky, DB; Waters, AH; Zhdanov, AV | 1 |
| Cipolleschi, MG; D'Amico, M; Dello Sbarba, P; Fredducci, D; Marzi, I; Olivotto, M; Rovida, E; Santini, R; Stecca, B; Stivarou, T; Torre, E; Vinci, MC | 1 |
| Fukuoka, H; Imamura, H; Inagaki, N; Kakizuka, A; Kioka, H; Nagashima, K; Noji, H; Takashima, S; Tanaka, T | 1 |
| Amathieu, R; Bouchemal, N; Dhonneur, G; Haouache, H; Kamoun, W; Le Moyec, L; Nahon, P; Savarin, P; Triba, MN; Trinchet, JC | 1 |
| Nilsen, LH; Sonnewald, U; Witter, MP | 1 |
| Calvaruso, MA; DeBerardinis, RJ; Hensley, CT; Jiang, L; Kim, J; Ko, B; Lumata, L; Merritt, ME; Mitsche, M; Rutter, J; Sudderth, J; Wasti, AT; Yang, C | 1 |
| Ciaraldi, TP; Divakaruni, AS; Green, CR; Henry, RR; Metallo, CM; Murphy, AN; Parker, SJ; Vacanti, NM | 1 |
| Hasan, NM; Kendrick, MA; Longacre, MJ; MacDonald, MJ; Stoker, SW | 1 |
| Bendotti, C; Cantoni, L; Cimini, S; Keun, HC; Rizzardini, M; Siskos, AP; Valbuena, GN | 1 |
| Brown, KS; Burgess, SC; Cox, JE; Dohlman, A; Fu, X; Gray, LR; Lane, EE; Miao, R; Norris, AW; Oonthonpan, L; Pewa, AD; Potthoff, MJ; Rauckhorst, AJ; Rutter, J; Sharma, A; Sultana, MR; Taylor, EB; Tompkins, SC; Xie, J; Zepeda-Orozco, D | 1 |
| Artyomov, MN; Avizonis, D; Blagih, J; Bridon, G; Choinière, L; Coelho, PP; Elder, DJ; Flynn, BR; Gingras, MC; Griss, T; Jones, RG; Loginicheva, E; Ntimbane, T; Pause, A; Raissi, TC; Samborska, B; Sergushichev, A; Tavaré, JM; Thomas, EC; Vincent, EE | 1 |
| Fujita, J; Fukuda, K; Hattori, F; Hirano, A; Hishiki, T; Kanazawa, H; Kishino, Y; Kuroda, T; Matsuura, T; Nakajima, K; Ohno, R; Okada, M; Sano, M; Sato, Y; Seki, T; Suematsu, M; Tohyama, S; Yasuda, S; Yuasa, S | 1 |
| Ferenczi, S; Jády, AG; Kőhidi, T; Madarász, E; Nagy, ÁM; Tretter, L | 1 |
| Lisanti, MP; Martinez-Outschoorn, UE; Peiris-Pagés, M; Pestell, RG; Sotgia, F | 1 |
| Ammar, Z; Herzig, S; Hörl, M; Krznar, P; Martinou, JC; Montessuit, S; Pierredon, S; Vanderperre, B; Zamboni, N | 1 |
| Chen, Y; Hertz, L; Peng, L; Song, D | 1 |
| Cebeci, A; Cetinbas, NM; DeBerardinis, RJ; Harris, RC; Negri, GL; Sorensen, PH; Sudderth, J; Yılmaz, ÖH | 1 |
| Bartnik-Olson, BL; Ghavim, SS; Harris, NG; Shijo, K; Sutton, RL | 1 |
| Athanasiadis, A; Bletsou, AA; Gika, HG; Makrydimas, G; Raikos, N; Theodoridis, GA; Thomaidis, NS; Virgiliou, C; Witting, M; Zafrakas, M | 1 |
| Basu, A; Bloch, W; Geiger, H; Kochanek, S; Krug, L; Maity, P; Meyer, P; Scharffetter-Kochanek, K; Singh, K; Treiber, N; Vander Beken, S; Wlaschek, M | 1 |
| Bertilsson, S; Dinasquet, J; Logares, R; Richert, I; Riemann, L; Yager, P | 1 |
| Board, M; Callaghan, R; Carr, C; Clarke, K; Lopez, C; van den Bos, C | 1 |
| Cararo-Lopes, E; Carvalho, AS; Da Poian, AT; Dias, MH; Fernandes-Siqueira, LO; Galina, A; Ketzer, LA; Zeidler, JD | 1 |
| Chitnis, NB; Gupta, SK; Kushwaha, H; Nalage, VHH; Salvi, D; Sharma, A; Shukla, P; Srivastava, SK | 1 |
| Neale, SA; Salt, TE; Sathyasaikumar, KV; Schwarcz, R; Tararina, M; Weisz, F; Wu, HQ | 1 |
| Bilz, NC; Claus, C; Geyer, H; Hübner, D; Hübschen, JM; Jahn, K; Liebert, UG; Lorenz, M; Lüdtke, A; Mankertz, A | 1 |
| Bizjak, M; Malavašič, P; Pavlin, M; Pirkmajer, S | 1 |
| Bader, DA; Bankson, JA; Chen, R; Coarfa, C; Foley, C; Hamilton, MP; Hartig, SM; Ittmann, MM; Martini-Stoica, H; McGuire, SE; Mitsiades, N; O'Malley, BW; Panigrahi, A; Putluri, N; Putluri, V; Rajapakshe, K; Saha, PK; Smith, EA; Sreekumar, A; Walker, C; Zong, L | 1 |
| Baldi, R; Chang, CY; Liu, J; Liu, W; Liu, X; Locasale, JW; McDonnell, DP; Park, S; Safi, R | 1 |
| Buchanan, JL; Dupuy, AJ; Gray, LR; Mapuskar, KA; Noterman, MF; Oonthonpan, L; Pewa, AD; Rauckhorst, AJ; Scerbo, DA; Sharma, A; Sheldon, RD; Solst, SR; Spitz, DR; Taylor, EB; Tompkins, SC | 1 |
| Chen, J; Chen, X; Gao, W; Hao, B; Huang, M; Huang, W; Li, K; Liu, J; Liu, Q; Liu, R; Shao, Y; Wang, J; Wang, Q; Wei, Z; Xu, P; Xu, Y; Ye, S; Zeng, S; Zhang, H; Zhang, Q; Zhong, Z | 1 |
| Baguley, BC; Dechaume, AL; Katt, WP; Leung, EY; Murray, PM; Singleton, DC | 1 |
| Alherz, M; Alshangiti, A; Barry, D; Lee, D; O'Keeffe, G; Roddy, D; White, R | 1 |
| Bergers, G; Fendt, SM | 1 |
| Fang, DM; Lenchine, RV; Proud, CG; Rao, SR; Wang, X | 1 |
| Bilonoha, OO; Ivasechko, II; Manko, BO; Manko, VV; Voloshyn, DM; Zub, AM | 1 |
| Alahmad, A; Alaqeel, A; Albash, B; Catalina, V; Fang, F; Fu, S; Fu, X; Han, X; Jiang, H; Li, L; Liu, S; Liu, Z; McFarland, R; Prokisch, H; Song, T; Taylor, RW; Wang, J; Xu, M | 1 |
| Abiko, Y; Kobayashi, Y; Liu, S; Otani, H; Sasaki, S; Sato, S; Shinohara, Y; Takahashi, N; Wang, X; Washio, J | 1 |
| Bazer, FW; Burghardt, RC; Cain, JW; Johnson, GA; Kramer, AC; McLendon, BA; Seo, H; Wu, G | 1 |
| Alam, K; Bastani, NE; Chowdhury, A; Grimolizzi, F; Kolan, S; Li, G; Skålhegg, BS; Wik, JA | 1 |
| Bao, MH; Chan, CY; Chen, Y; Lee, D; Tse, AP; Wei, L; Wong, BP; Wong, CC; Yang, C; Yuen, VW; Zhang, MS | 1 |
12 review(s) available for glutamine and pyruvic acid
| Article | Year |
|---|---|
Metabolic substrates, cellular energy production, and the regulation of proximal tubular transport.
Topics: Amino Acids; Animals; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Citric Acid Cycle; Culture Techniques; Energy Metabolism; Fatty Acids; Glucose; Glutamine; Glycogen; Humans; Ketones; Kidney; Kidney Tubules, Proximal; Lactates; Lactic Acid; Lipid Metabolism; Oxidation-Reduction; Perfusion; Pyruvates; Pyruvic Acid | 1985 |
Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance.
Topics: Amino Acids; Animals; Glutaminase; Glutamine; Intestine, Small; Ketoglutarate Dehydrogenase Complex; Kinetics; Lymphocyte Activation; Lymphocytes; Models, Biological; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvates; Pyruvic Acid; Rats | 1985 |
Membrane cholesterol, tumorigenesis, and the biochemical phenotype of neoplasia.
Topics: Acetates; Animals; Asparagine; Aspartic Acid; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cholesterol; Citric Acid Cycle; Electron Spin Resonance Spectroscopy; Glucose; Glutamates; Glutamic Acid; Glutamine; Lipid Bilayers; Liver Neoplasms, Experimental; Membrane Lipids; Mitochondria; Mitochondria, Liver; Models, Biological; Neoplasms; Oxygen Consumption; Phenotype; Purines; Pyrimidines; Pyruvates; Pyruvic Acid; Surface Properties | 1981 |
Glycolysis, glutaminolysis and cell proliferation.
Topics: Animals; Cell Division; Cytosol; Energy Metabolism; Glucose; Glutamine; Glycolysis; Mitochondria; Mutation; Neoplasms, Experimental; Pentoses; Pyruvates; Pyruvic Acid | 1982 |
The tricarboxylic acid cycle in human skeletal muscle: is there a role for nutritional intervention?
Topics: Citric Acid Cycle; Dietary Supplements; Energy Metabolism; Glutamine; Humans; Muscle Contraction; Muscle, Skeletal; Nutritional Physiological Phenomena; Pyruvic Acid | 1999 |
Energy metabolism in brain cells: effects of elevated ammonia concentrations.
Topics: Ammonia; Animals; Astrocytes; Brain; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Glycolysis; Humans; Hyperammonemia; Neurons; Pyruvic Acid | 2007 |
Human fetal brain chemistry as detected by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Fetus; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Acid; Magnetic Resonance Spectroscopy; Protons; Pyruvic Acid | 2009 |
Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells.
Topics: Adaptation, Biological; Cell Hypoxia; Cell Proliferation; Energy Metabolism; Gene Expression Regulation; Genes, myc; Glucose; Glutamine; Humans; Lactic Acid; Metabolic Networks and Pathways; Mitochondria; Neoplasms; Oxidative Phosphorylation; Phosphatidylinositol 3-Kinase; Protein Serine-Threonine Kinases; Pyruvic Acid | 2011 |
Dynamic nuclear polarization in metabolic imaging of metastasis: common sense, hypersense and compressed sensing.
Topics: Bicarbonates; Diagnostic Imaging; Glutamine; Humans; Magnetic Resonance Spectroscopy; Neoplasm Metastasis; Neoplasms; Pyruvic Acid | 2010 |
Cancer metabolism: a therapeutic perspective.
Topics: Acetyl Coenzyme A; Adaptation, Physiological; Amino Acids; Antineoplastic Agents; Antioxidants; Autophagy; Blood Glucose; Energy Metabolism; Epigenomics; Fatty Acids; Genetic Heterogeneity; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Lipids; Mitochondria; Mitochondrial Ribosomes; Neoplasms; Nucleic Acids; Oxidative Stress; Pyruvic Acid; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Microenvironment | 2017 |
Multifactorial Effects on Different Types of Brain Cells Contribute to Ammonia Toxicity.
Topics: Ammonia; Animals; Astrocytes; Brain; Cyclic GMP; Energy Metabolism; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Lactic Acid; Liver Failure, Acute; Potassium; Pyruvic Acid; Sodium-Potassium-Exchanging ATPase; Solute Carrier Family 12, Member 2 | 2017 |
The metabolism of cancer cells during metastasis.
Topics: Acetates; Adenosine Triphosphate; Animals; Cell Plasticity; Fatty Acids; Glutamine; Humans; Lactic Acid; Neoplasm Metastasis; Neoplasms; Neoplastic Cells, Circulating; Pyruvic Acid | 2021 |
3 trial(s) available for glutamine and pyruvic acid
| Article | Year |
|---|---|
Glutamine improves human preimplantation development in vitro.
Topics: Blastocyst; Cell Count; Cell Death; Culture Media; Culture Techniques; Embryonic Development; Female; Fertilization in Vitro; Glutamine; Humans; Lactates; Mitosis; Pregnancy; Prospective Studies; Pyruvic Acid | 1998 |
Effects of taurine on human embryo development in vitro.
Topics: Blastocyst; Cell Count; Cell Death; Culture Media; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Glutamine; Humans; Lactic Acid; Pyruvic Acid; Taurine | 1999 |
A randomized, controlled trial of parenteral glutamine in ill, very low birth-weight neonates.
Topics: Amino Acids; Ammonia; Birth Weight; Enteral Nutrition; Female; Gestational Age; Glutamine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Lactic Acid; Liver Function Tests; Male; Parenteral Nutrition; Pyruvic Acid; Risk Factors; Time Factors; Urea | 2003 |
198 other study(ies) available for glutamine and pyruvic acid
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Developmentally related changes in the uptake and metabolism of glucose, glutamine and pyruvate by cattle embryos produced in vitro.
Topics: Analysis of Variance; Animals; Blastocyst; Cattle; Cells, Cultured; Cleavage Stage, Ovum; Fertilization in Vitro; Glucose; Glutamine; Morula; Pyruvates; Pyruvic Acid | 1992 |
Requirement for glucose in ligand-stimulated meiotic maturation of cumulus cell-enclosed mouse oocytes.
Topics: 3-O-Methylglucose; Animals; Bucladesine; Cell Survival; Concanavalin A; Culture Media; Deoxyglucose; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Glucose; Glutamine; Hexoses; In Vitro Techniques; Ligands; Meiosis; Methylglucosides; Mice; Mice, Inbred C57BL; Oocytes; Oogenesis; Phloretin; Pyruvates; Pyruvic Acid; Time Factors | 1992 |
Glutamine and glucose metabolism in bovine blood lymphocytes.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Blood Glucose; Cattle; Glutamates; Glutamic Acid; Glutamine; Humans; In Vitro Techniques; Lactates; Lactic Acid; Lymphocytes; Male; Pyruvates; Pyruvic Acid; Rats | 1992 |
A continuous multistage roller reactor for animal cell culture: 1. Patterns of growth, production and catabolism of a murine hybridoma.
Topics: Alanine; Animals; Antibodies, Monoclonal; Cell Division; Glucose; Glutamine; Hybridomas; Kinetics; Methods; Mice; Pyruvates; Pyruvic Acid | 1990 |
Effects of congenital hyperammonemia on the cerebral and hepatic levels of the intermediates of energy metabolism in spf mice.
Topics: Adenosine Triphosphate; Ammonia; Animals; Brain; Coenzyme A; Energy Metabolism; Glucose; Glutamine; Ketoglutaric Acids; Liver; Mice; Mice, Mutant Strains; NAD; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Oxidation-Reduction; Pyruvates; Pyruvic Acid; X Chromosome | 1992 |
Multiple abnormalities in insulin responses to nonglucose nutrients in neonatally streptozotocin diabetic rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Caprylates; Diabetes Mellitus, Experimental; Dichloroacetic Acid; Drug Synergism; Fatty Acids, Nonesterified; Female; Glucose; Glutamine; Insulin; Insulin Secretion; Male; Pancreas; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinates; Succinic Acid | 1991 |
Glucose and glutamine metabolism in rat macrophages: enhanced glycolysis and unaltered glutaminolysis in spontaneously diabetic BB rats.
Topics: Adenosine Triphosphate; Ammonia; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; Female; Glucose; Glutamates; Glutamine; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Macrophages; Pentose Phosphate Pathway; Peritoneal Cavity; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred BB | 1991 |
Glutamine and glucose metabolism in thymocytes from normal and spontaneously diabetic BB rats.
Topics: Adenosine Triphosphate; Animals; Cell Count; Diabetes Mellitus, Experimental; Female; Glucose; Glutamine; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred BB; T-Lymphocytes | 1991 |
Energy substrate requirements for in-vitro development of hamster 1- and 2-cell embryos to the blastocyst stage.
Topics: Amino Acids; Animals; Blastocyst; Cleavage Stage, Ovum; Cricetinae; Culture Media; Culture Techniques; Dose-Response Relationship, Drug; Energy Metabolism; Glutamine; Lactates; Lactic Acid; Morula; Pyruvates; Pyruvic Acid | 1991 |
Substrate and pH effects on glutamine synthesis in rat liver. Consequences for acid-base regulation.
Topics: Acid-Base Equilibrium; Ammonia; Ammonium Chloride; Animals; Glucose; Glutamine; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Male; Nitrogen; Ornithine; Portal Vein; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1991 |
Maximal activity of phosphate-dependent glutaminase and glutamine metabolism in septic rats.
Topics: Alanine; Animals; Arteries; Glutaminase; Glutamine; Intestinal Mucosa; Kidney; Lactates; Lactic Acid; Liver; Lymph Nodes; Lymphocytes; Male; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sepsis; Veins | 1991 |
Carbohydrate utilization in exercising muscle in subtotally nephrectomized rabbits.
Topics: Alanine; Animals; Carbohydrate Metabolism; Glutamine; Glycogen; Ketoglutaric Acids; Kidney; Kidney Failure, Chronic; Lactates; Lactic Acid; Muscles; Nephrectomy; Physical Exertion; Pyruvates; Pyruvic Acid; Rabbits | 1990 |
Pyruvate utilization of rabbit reticulocytes--a compartmental study.
Topics: Alanine; Animals; Aspartic Acid; Cell Compartmentation; Citric Acid Cycle; Decarboxylation; Glutamine; Kinetics; Mitochondria; Pyruvates; Pyruvic Acid; Rabbits; Reticulocytes | 1990 |
Ammoniagenesis by cultured human renal cortical epithelial cells: study with 15N.
Topics: Ammonia; Cells, Cultured; Epithelium; Glutamates; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Kidney Cortex; Nitrogen Isotopes; Pyruvates; Pyruvic Acid | 1989 |
End products of glutamine oxidation in MC-29 virus-induced chicken hepatoma mitochondria.
Topics: Animals; Aspartate Aminotransferases; Aspartic Acid; Chickens; Citric Acid Cycle; Glutamates; Glutamic Acid; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria, Liver; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Stimulation of glutamine metabolism by the antiepileptic drug, sodium valproate, in isolated dog kidney tubules.
Topics: Alanine; Ammonia; Animals; Aspartic Acid; Dogs; Female; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Kidney Tubules; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Valproic Acid | 1989 |
Human interleukin-1 beta induced stimulation of insulin release from rat pancreatic islets is accompanied by an increase in mitochondrial oxidative events.
Topics: Animals; Cells, Cultured; Glucose; Glutamine; Glycolysis; Humans; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Leucine; Male; Mitochondria; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Recombinant Proteins | 1989 |
Role of glutamine aminotransferase in glutamine catabolism by Saccharomyces cerevisiae under microaerophilic conditions.
Topics: Aerobiosis; Glutaminase; Glutamine; Glyoxylates; Mutation; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae; Species Specificity; Transaminases | 1989 |
Effects of hyperthermia on the peripheral metabolism of ammonia and glutamine.
Topics: Acid-Base Equilibrium; Alanine; Ammonia; Arteries; Blood Glucose; Body Temperature; Fatty Acids, Nonesterified; Female; Fever; Forearm; Glutamine; Humans; Lactates; Lactic Acid; Male; Middle Aged; Pyruvates; Pyruvic Acid | 1989 |
Oxidation of cytosolic NADH by the malate-aspartate shuttle in MC29 hepatoma cells.
Topics: Aminooxyacetic Acid; Animals; Aspartic Acid; Chickens; Cytosol; Glutamine; Lactates; Lactic Acid; Liver Neoplasms, Experimental; Malates; Mitochondria; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1989 |
Ammonia intoxication: effects on cerebral cortex and spinal cord.
Topics: Acetates; Ammonia; Animals; Blood; Carbon Dioxide; Cats; Cerebral Cortex; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Spinal Cord | 1985 |
Effect of protein intake on amino acid catabolism and gluconeogenesis by isolated hepatocytes from the cat (Felis domestica).
Topics: Alanine; Amino Acids; Animals; Cats; Dietary Proteins; Gluconeogenesis; Glutamine; Kinetics; Liver; Pyruvates; Pyruvic Acid; Threonine; Tryptophan Oxygenase; Tyrosine Transaminase; Urea | 1985 |
Pathway of ammonium assimilation in Streptomyces venezuelae examined by amino acid analyses and 15N nuclear magnetic resonance spectroscopy.
Topics: Alanine; Ammonium Sulfate; Anaerobiosis; Glutamates; Glutamic Acid; Glutamine; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Nitrogen Radioisotopes; Pyruvates; Pyruvic Acid; Species Specificity; Streptomyces | 1985 |
The metabolic response of the kidney to acute sodium lactate alkalosis.
Topics: Alanine; Alanine Transaminase; Alkalosis; Animals; Dogs; Glomerular Filtration Rate; Glutamates; Glutamic Acid; Glutamine; Kidney; Kidney Cortex; Lactates; Lactic Acid; Liver; Muscles; Pyruvates; Pyruvic Acid | 1985 |
Transamination pathways influencing L-glutamine and L-glutamate oxidation by rat enterocyte mitochondria and the subcellular localization of L-alanine aminotransferase and L-aspartate aminotransferase.
Topics: Alanine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Intestinal Mucosa; Intestines; Malates; Male; Mitochondria; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Subcellular Fractions | 1985 |
Effects of branched chain amino acids, pyruvate, or ketone bodies on the free amino acid pool and release from brain cortex slices of normal and streptozotocin-diabetic rats.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Ketone Bodies; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1987 |
Pathways for organic osmolyte synthesis in rabbit renal papillary tissue, a metabolic study using 13C-labeled substrates.
Topics: Alanine; Aldehyde Reductase; Animals; Citric Acid Cycle; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycerylphosphorylcholine; Glycolysis; Inositol; Kidney Medulla; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Pyruvates; Pyruvic Acid; Rabbits; Sorbitol | 1988 |
The effect of ketone bodies on alanine and glutamine metabolism in isolated skeletal muscle from the fasted chick.
Topics: Alanine; Amino Acids, Branched-Chain; Animals; Aspartic Acid; Chickens; Fasting; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Intracellular Fluid; Ketone Bodies; Muscles; Pyruvates; Pyruvic Acid | 1988 |
The coupling of metabolic to secretory events in pancreatic islets. The possible role of glutathione reductase.
Topics: Animals; Calcium; Carmustine; Cyclic AMP; Glutamine; Glutathione; Glutathione Reductase; Insulin; Islets of Langerhans; Lactates; Lactic Acid; Leucine; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1985 |
Metabolism of radiolabelled energy-yielding substrates by rat Sertoli cells.
Topics: Animals; Bucladesine; Cells, Cultured; Energy Metabolism; Follicle Stimulating Hormone; Glucose; Glutamine; Leucine; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Sertoli Cells | 1986 |
Substrate utilization for lactate and energy production by heat-shocked L929 cells.
Topics: Adenosine Triphosphate; Animals; Carbon Dioxide; Cell Line; Citric Acid Cycle; Energy Metabolism; Fibroblasts; Glucose; Glutamine; Heat-Shock Proteins; Lactates; Lactic Acid; Mice; NAD; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Pyruvic Acid; Temperature | 1986 |
Compartmentation of 14CO2 in the perfused rat liver.
Topics: Acetazolamide; Acetoacetates; Animals; Carbon Dioxide; Cell Compartmentation; Formates; Glutamine; Keto Acids; Liver; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1987 |
Physiological role of glutaminase activity in Saccharomyces cerevisiae.
Topics: Glutamates; Glutaminase; Glutamine; Mutation; Pyruvates; Pyruvic Acid; Saccharomyces cerevisiae | 1987 |
Measurement of the metabolism of energy substrates in individual bovine blastocysts.
Topics: Animals; Blastocyst; Cattle; Cells, Cultured; Citric Acid Cycle; Energy Metabolism; Female; Glucose; Glutamine; Pentose Phosphate Pathway; Pyruvates; Pyruvic Acid | 1988 |
Glutamine is responsible for stimulating glycolysis by L929 cells.
Topics: Animals; Energy Metabolism; Glutamine; Glycolysis; Insulin; L Cells; Lactates; Lactic Acid; Mice; Oxidation-Reduction; Pyruvates; Pyruvic Acid | 1986 |
Studies on the mechanism by which glutamine and heat shock increase lactate synthesis by L929 cells in the presence of insulin.
Topics: 3-O-Methylglucose; Aminooxyacetic Acid; Cell Line; Deoxyglucose; Glutamine; Glycolysis; Hot Temperature; Insulin; Kinetics; Lactates; Lactic Acid; Methylglucosides; Pyruvates; Pyruvic Acid; Transaminases | 1986 |
A single amino acid substitution deregulates a bacterial lactate dehydrogenase and stabilizes its tetrameric structure.
Topics: Allosteric Regulation; Allosteric Site; Arginine; Bacterial Proteins; Binding Sites; Fructosediphosphates; Geobacillus stearothermophilus; Glutamine; L-Lactate Dehydrogenase; Mutation; NAD; Protein Binding; Protein Conformation; Pyruvates; Pyruvic Acid | 1987 |
Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Fatty Acids; Female; Glucose; Glutamine; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Macrophages; Mice; Mice, Inbred C57BL; Oxygen Consumption; Pyruvates; Pyruvic Acid | 1987 |
Effect of acetazolamide on renal metabolism and ammoniagenesis in the dog.
Topics: Acetazolamide; Acidosis; Ammonium Chloride; Animals; Chronic Disease; Citrates; Citric Acid; Dogs; Glutamine; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kidney Cortex; Kidney Tubules; Lactates; Lactic Acid; Pyruvates; Pyruvic Acid; Renal Circulation | 1987 |
Intra- and inter-nephron heterogeneity of gluconeogenesis in the rat: effects of chronic metabolic acidosis and potassium depletion.
Topics: Acidosis; Animals; Chronic Disease; Gluconeogenesis; Glutamine; In Vitro Techniques; Kidney Tubules, Proximal; Male; Nephrons; Potassium Deficiency; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1986 |
Intracellular distribution of some enzymes of the glutamine utilisation pathway in rat lymphocytes.
Topics: Animals; Aspartate Aminotransferases; Cell Compartmentation; Cytosol; Glutamine; Lymphocytes; Malate Dehydrogenase; Malates; Mitochondria; NAD; Oxaloacetates; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Carboxylase; Pyruvate Kinase; Pyruvates; Pyruvic Acid; Rats | 1986 |
Glutamine metabolism in rat hepatocytes. Stimulation by a nonmetabolizable analog of leucine.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Amino Acids, Cyclic; Animals; Glucagon; Glutamine; Hydroxybutyrates; Ketoglutaric Acids; Leucine; Liver; Malates; Ornithine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1986 |
Utilization of pyruvate and pyruvate precursors by normal and carcinogen-altered rat tracheal epithelial cells in culture.
Topics: Alanine; Animals; Carbon Radioisotopes; Cells, Cultured; Glucose; Glutamine; Glycolysis; Lactates; Lactic Acid; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Trachea; Tracheal Neoplasms | 1986 |
Effects of the hyperglycaemic agent 3-aminopicolinate on amino acid release by rat muscle in vitro.
Topics: Amino Acids; Animals; Glutamine; Hyperglycemia; In Vitro Techniques; Male; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Malic enzyme and malate dehydrogenase activities in rat tracheal epithelial cells during the progression of neoplasia.
Topics: Animals; Cells, Cultured; Epithelium; Glutamine; Isoenzymes; Malate Dehydrogenase; Pyruvates; Pyruvic Acid; Rats; Trachea; Tracheal Neoplasms | 1985 |
Respiratory metabolism of L-929 cells at different water contents and volumes.
Topics: Animals; Culture Media; Deoxyglucose; Fibroblasts; Glucose; Glutamine; Iodoacetates; Iodoacetic Acid; Mice; Oxygen Consumption; Pyruvates; Pyruvic Acid; Sorbitol; Time Factors; Water | 1985 |
Heat-shock treatment lethal for mammalian cells deprived of glucose and glutamine: protection by alpha-keto acids.
Topics: Animals; Blood; Butyrates; Cell Line; Cell Survival; Cricetinae; Fibroblasts; Glucose; Glutamine; Heat-Shock Proteins; Hot Temperature; Keto Acids; Ketoglutaric Acids; Oxaloacetates; Pyruvates; Pyruvic Acid | 1985 |
Incorporation of acetate into acetylcholine, acetylcarnitine, and amino acids in the Torpedo electric organ.
Topics: Acetates; Acetic Acid; Acetylcarnitine; Acetylcholine; Animals; Carnitine; Choline; Electric Organ; Electric Stimulation; Female; Glutamine; Male; Nerve Endings; Pyruvates; Pyruvic Acid; Synaptosomes; Torpedo | 1985 |
Some aspects on amino acid metabolism in relation to glucose and ketone bodies in brain cortex slices of the rat.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Amino Acids, Branched-Chain; Animals; Cerebral Cortex; Glucose; Glutamates; Glutamic Acid; Glutamine; Hydroxybutyrates; In Vitro Techniques; Ketone Bodies; Pyruvates; Pyruvic Acid; Rats | 1982 |
Lactate, alanine and glutamine metabolism in isolated canine pup liver cells.
Topics: Alanine; Ammonia; Animals; Dogs; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea | 1983 |
Effect of phenylephrine on glutamate and glutamine metabolism in isolated perfused rat liver.
Topics: Animals; Carbon Dioxide; Citric Acid Cycle; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Liver; Male; Perfusion; Phenylephrine; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis.
Topics: Alanine; Animals; Glutamates; Glutamic Acid; Glutamine; In Vitro Techniques; Lactates; Lactic Acid; Male; Muscles; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Starvation; Substrate Specificity | 1984 |
Effects of pyruvate on the growth of normal and transformed hamster embryo fibroblasts.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Glucose; Glutamine; Lactates; Lactic Acid; Polyomavirus; Pyruvates; Pyruvic Acid | 1982 |
Effectors of fatty acid synthesis in hepatoma tissue culture cells.
Topics: Ammonium Chloride; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Fatty Acids; Glucose; Glutamine; Glycolysis; Liver; Liver Neoplasms, Experimental; Male; Oleic Acid; Oleic Acids; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1982 |
Regulation of insulin secretion by energy metabolism in pancreatic B-cell mitochondria. Studies with a non-metabolizable leucine analogue.
Topics: Adenosine Triphosphate; Amino Acids; Amino Acids, Branched-Chain; Amino Acids, Cyclic; Animals; Energy Metabolism; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Malates; Male; Mice; Mice, Obese; Mitochondria; Oxygen Consumption; Pyruvates; Pyruvic Acid; Secretory Rate | 1984 |
The coupling of metabolic to secretory events in pancreatic islets. The cytosolic redox state.
Topics: Animals; Cytosol; Glutamine; In Vitro Techniques; Islets of Langerhans; Isocitrate Dehydrogenase; Leucine; Malate Dehydrogenase; Malates; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1984 |
Inhibition of 2-oxoglutarate metabolism by lithium in the isolated rat kidney cortex tubules.
Topics: Animals; Gluconeogenesis; Glutamine; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kidney Cortex; Lithium; Malates; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1984 |
3-Aminopicolinate inhibits phosphoenolpyruvate carboxykinase in hepatocytes and increases release of gluconeogenic precursors from peripheral tissues.
Topics: Animals; Blood Glucose; Gluconeogenesis; Glutamine; Kidney; Lactates; Lactic Acid; Liver; Male; Phosphoenolpyruvate Carboxykinase (GTP); Picolinic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Succinates | 1984 |
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic interaction of L-glutamine and 2-ketoisocaproate in pancreatic islets.
Topics: Animals; Drug Synergism; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Transaminases | 1981 |
The stimulus-secretion coupling of glucose-induced insulin release: effect of aminooxyacetate upon nutrient-stimulated insulin secretion.
Topics: Acetates; Aminooxyacetic Acid; Animals; Glucose; Glutamine; Insulin; Islets of Langerhans; Keto Acids; Leucine; Malates; Pyruvates; Pyruvic Acid; Rats | 1982 |
Organic acid metabolism in a patient with ornithine transcarbamylase deficiency.
Topics: Ammonia; Ammonium Chloride; Child; Citrates; Citric Acid; Female; Glutamine; Humans; Ketoglutaric Acids; Ornithine Carbamoyltransferase Deficiency Disease; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid | 1982 |
Influence of pyruvate on ammonia metabolism by renal cortical mitochondria.
Topics: Acidosis; Ammonia; Animals; Citrates; Citric Acid; Glutamine; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kidney Cortex; Male; Mitochondria; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1982 |
Regulation of glutamine and pyruvate oxidation in cultured adrenocortical cells by cortisol, antioxidants, and oxygen: effects on cell proliferation.
Topics: Adrenal Cortex; Aminooxyacetic Acid; Animals; Antioxidants; Cattle; Cell Division; Cell Survival; Cells, Cultured; Glutamine; Hydrocortisone; Oxygen; Pyruvates; Pyruvic Acid | 1981 |
The conversion of alanine into glutamine in guinea-pig renal cortex. Essential role of pyruvate carboxylase.
Topics: Alanine; Alanine Transaminase; Animals; Fluoroacetates; Glutamine; Guinea Pigs; In Vitro Techniques; Ketoglutaric Acids; Kidney Cortex; Kidney Tubules; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid | 1981 |
Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.
Topics: Brain; Carbon Isotopes; Citric Acid Cycle; Glucose; Glutamic Acid; Glutamine; Glycolysis; Humans; Ketoglutaric Acids; Ketone Bodies; Kinetics; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Mathematics; Models, Biological; Oxygen Consumption; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid | 1995 |
Isotopomer studies of gluconeogenesis and the Krebs cycle with 13C-labeled lactate.
Topics: Acetyl Coenzyme A; Alanine; Animals; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Gluconeogenesis; Glucose; Glutamates; Glutamic Acid; Glutamine; Isotope Labeling; Lactates; Lactic Acid; Liver; Male; Oxaloacetates; Phosphoenolpyruvate; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Guanosine Diphosphate; Guanosine Triphosphate; Lactates; Lactic Acid; Male; Neurotransmitter Agents; Nitro Compounds; Oxygen Consumption; Phosphocreatine; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes | 1994 |
Glucose, galactose, and glutamine metabolism in pig isolated enterocytes during development.
Topics: Animals; Animals, Newborn; Animals, Suckling; Female; Galactose; Glucose; Glutamine; Glycogen; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Kinetics; Lactates; Lactic Acid; Oxidation-Reduction; Pregnancy; Pyruvates; Pyruvic Acid; Swine | 1994 |
The role of reduced nicotinamide adenine dinucleotide phosphate in glucose- and temperature-dependent doxorubicin cytotoxicity.
Topics: Animals; Cell Survival; Culture Media; DNA Damage; Doxorubicin; Drug Resistance; Glucose; Glutamine; L Cells; Methylene Blue; Mice; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Temperature; Uridine | 1993 |
Propionate regulates lymphocyte proliferation and metabolism.
Topics: Adult; Animals; B-Lymphocytes; Cells, Cultured; DNA; Glucose; Glutamine; Humans; Lactates; Lactic Acid; Lipids; Lymphocyte Activation; Lymphocytes; Male; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; T-Lymphocytes | 1993 |
Effects of glucocorticoids on lymphocyte metabolism.
Topics: Animals; Cells, Cultured; Circadian Rhythm; Decarboxylation; Dexamethasone; Glucose; Glutamine; Lymphocytes; Male; Metyrapone; Mifepristone; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1993 |
Increased glutamine metabolism in bovine cumulus cell-enclosed and denuded oocytes after in vitro maturation with luteinizing hormone.
Topics: Animals; Carbon Dioxide; Cattle; Cell Separation; Culture Media; Female; Glutamine; In Vitro Techniques; Luteinizing Hormone; Oocytes; Pyruvates; Pyruvic Acid | 1993 |
Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes.
Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Biological Transport; Cell Compartmentation; Cells, Cultured; Citric Acid Cycle; Culture Media, Conditioned; Extracellular Space; Glutamic Acid; Glutamine; Lactates; Magnetic Resonance Spectroscopy; Mice; Pyruvates; Pyruvic Acid; Rats | 1996 |
Differentiation-dependent expression of CA V and the role of carbonic anhydrase isozymes in pyruvate carboxylation in adipocytes.
Topics: 3T3 Cells; Adenosine Triphosphate; Adipocytes; Animals; Carbonic Anhydrases; Ethoxzolamide; Glutamine; Male; Mice; Pyruvate Carboxylase; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Rats, Zucker | 1996 |
Developmental capacity, energy metabolism and ultrastructure of mature oocytes from prepubertal and adult sheep.
Topics: Aging; Animals; Blastocyst; Cytoplasm; Cytoplasmic Granules; Energy Metabolism; Female; Glucose; Glutamine; Mitochondria; Oocytes; Organelles; Pyruvic Acid; Sexual Maturation; Sheep | 1996 |
Metabolism of [U-13C5] glutamine in cultured astrocytes studied by NMR spectroscopy: first evidence of astrocytic pyruvate recycling.
Topics: Alanine; Animals; Animals, Newborn; Astrocytes; Carbon Isotopes; Cells, Cultured; Cerebral Cortex; Gas Chromatography-Mass Spectrometry; Glutamine; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Pyruvic Acid | 1996 |
Regulation of [15N]urea synthesis from [5-15N]glutamine. Role of pH, hormones, and pyruvate.
Topics: Amino Acids; Ammonia; Animals; Citric Acid Cycle; Citrulline; Gas Chromatography-Mass Spectrometry; Glucagon; Glutamates; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Insulin; Liver; Male; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Urea | 1996 |
New insights into the compartmentation of glutamate and glutamine in cultured rat brain astrocytes.
Topics: Aminooxyacetic Acid; Animals; Astrocytes; Brain; Carbon Dioxide; Cells, Cultured; Enzymes; Glutamic Acid; Glutamine; Kinetics; Pyruvic Acid; Rats; Tissue Distribution | 1996 |
Dichloroacetate inhibits glutamine oxidation by decreasing pyruvate availability for transamination.
Topics: Alanine; Animals; Cell Line; Cell Survival; Dichloroacetic Acid; Dose-Response Relationship, Drug; Glutamine; Hybridomas; Oxidation-Reduction; Pyruvic Acid; Time Factors | 1997 |
Gonadotropins, serum, and amino acids alter nuclear maturation, cumulus expansion, and oocyte morphology in hamster cumulus-oocyte complexes in vitro.
Topics: Actin Cytoskeleton; Amino Acids; Animals; Blood Proteins; Cattle; Cell Nucleus; Cricetinae; Culture Media; Female; Follicle Stimulating Hormone; Glucose; Glutamine; In Vitro Techniques; Lactic Acid; Luteinizing Hormone; Mesocricetus; Oocytes; Pyruvic Acid | 1997 |
Role of pyruvate carboxylase in facilitation of synthesis of glutamate and glutamine in cultured astrocytes.
Topics: Ammonia; Animals; Astrocytes; Carbon Dioxide; Cells, Cultured; Glutamic Acid; Glutamine; Pyruvate Carboxylase; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 1997 |
In vitro and ex vivo 13C-NMR spectroscopy studies of pyruvate recycling in brain.
Topics: Acetates; Animals; Aspartic Acid; Astrocytes; Brain; Carbon Isotopes; Cells, Cultured; Glutamine; Injections, Intraperitoneal; Injections, Subcutaneous; Magnetic Resonance Spectroscopy; Male; Mice; Pyruvic Acid; Rats; Rats, Wistar | 1998 |
Excitatory amino acid synthesis in hypoxic brain slices: does alanine act as a substrate for glutamate production in hypoxia?
Topics: Alanine; Animals; Brain; Carbon; Excitatory Amino Acids; Glutamic Acid; Glutamine; Guinea Pigs; Hypoxia; In Vitro Techniques; Intracellular Membranes; Osmolar Concentration; Perfusion; Pyruvic Acid; Reference Values; Substrate Specificity | 1998 |
Metabolism of glucose, pyruvate, and glutamine during the maturation of oocytes derived from pre-pubertal and adult cows.
Topics: Animals; Cattle; Cell Nucleus; Cell Size; Energy Metabolism; Female; Glucose; Glutamine; Histocytochemistry; Meiosis; Oocytes; Pyruvic Acid | 1999 |
Metabolic response of macrophages to injury promoted by the activated complement system.
Topics: Acetates; Animals; Cell Death; Cells, Cultured; Cholesterol; Cholesterol Esters; Complement Activation; Complement System Proteins; Glucose; Glutamine; Macrophages, Peritoneal; Male; Mevalonic Acid; Phospholipids; Pyruvic Acid; Rats; Rats, Wistar | 1999 |
Influence of carbon and nitrogen sources on Flavobacteriumgrowth and zeaxanthin biosynthesis.
Topics: Ammonia; Asparagine; beta Carotene; Carbon; Flavobacterium; Glucose; Glutamine; Nitrogen; Oxaloacetic Acid; Pyruvic Acid; Sucrose; Xanthophylls; Zeaxanthins | 1999 |
Gluconeogenesis in the liver of arthritic rats.
Topics: Alanine; Animals; Arthritis, Experimental; Gluconeogenesis; Glucose; Glutamine; Glycerol; Lactic Acid; Liver; Male; Oxygen; Pyruvic Acid; Rats; Rats, Wistar; Xylitol | 1999 |
Substrate oxidation and ATP supply in AS-30D hepatoma cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Division; Cell Respiration; Cytosol; Female; Glucose; Glutamic Acid; Glutamine; Glycogen; Glycolysis; Liver Neoplasms, Experimental; Mitochondria; Oxidation-Reduction; Oxidative Phosphorylation; Pyruvic Acid; Rats; Rats, Wistar; Substrate Specificity; Tumor Cells, Cultured | 2000 |
Hyperammonemia induced by administration of glucose and insulin after hepatopancreatectomy in rats.
Topics: Alanine; Ammonia; Animals; Energy Metabolism; Glucose; Glutamine; Glycolysis; Hepatectomy; Insulin; Lactic Acid; Male; Pancreatectomy; Pyruvic Acid; Rats; Rats, Wistar | 1999 |
Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex.
Topics: Amino Acids; Animals; Biological Transport; Brain Ischemia; Cerebral Cortex; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Energy Metabolism; Ethanolamines; gamma-Aminobutyric Acid; Glucose; Glutamine; Lactic Acid; Male; Pyruvic Acid; Quercetin; Rats; Rats, Sprague-Dawley | 2001 |
An unusual subcellular localization of GLUT1 and link with metabolism in oocytes and preimplantation mouse embryos.
Topics: Animals; Blastocyst; Blotting, Western; Cell Membrane; Cell Nucleus; Cells, Cultured; Embryo, Mammalian; Embryonic Development; Female; Glucose; Glucose Transporter Type 1; Glutamine; Immunohistochemistry; Mice; Microscopy, Confocal; Monosaccharide Transport Proteins; Oligonucleotides, Antisense; Oocytes; Pregnancy; Pyruvic Acid; Zygote | 2001 |
13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes.
Topics: Alanine; Animals; Animals, Newborn; Astrocytes; Brain; Brain Chemistry; Carbon Radioisotopes; Cell Compartmentation; Cell Extracts; Cells, Cultured; Culture Media; Cytosol; Energy Metabolism; Enzymes; Glucose; Glutamic Acid; Glutamine; Hydrogen; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2001 |
Rates of gluconeogenesis in perfused liver of alloxan-diabetic fed rats.
Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Fructose; Gluconeogenesis; Glucose; Glutamine; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Uric Acid | 2000 |
Development and evaluation of a boronate inhibitor of gamma-glutamyl transpeptidase.
Topics: Alanine; Alanine Transaminase; Aminobutyrates; Animals; Aspartate Aminotransferases; Binding Sites; Boron Compounds; Carbon Isotopes; Cell Division; Cell Line; Culture Media; Cysteine; gamma-Glutamyltransferase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Liver; Magnetic Resonance Spectroscopy; Oxaloacetic Acid; Protons; Pyruvic Acid; Rats | 2001 |
Rat liver responsiveness to gluconeogenic substrates during insulin-induced hypoglycemia.
Topics: Alanine; Animals; Blood Glucose; Cryoprotective Agents; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Pyruvic Acid; Rats; Rats, Wistar; Urea | 2001 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 2. Insights into the specific roles of D28 and E477 from the rates and stereospecificity of formation of carboligase side products.
Topics: Acetaldehyde; Acetoin; Acetolactate Synthase; Alanine; Aspartic Acid; Catalytic Domain; Circular Dichroism; Decarboxylation; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kinetics; Lactates; Pyruvate Decarboxylase; Pyruvic Acid; Recombinant Proteins; Saccharomyces cerevisiae; Stereoisomerism; Substrate Specificity | 2001 |
Multiple compartments with different metabolic characteristics are involved in biosynthesis of intracellular and released glutamine and citrate in astrocytes.
Topics: Amino Acids; Animals; Astrocytes; Carbon Radioisotopes; Cell Compartmentation; Cells, Cultured; Cerebellum; Citric Acid; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamic Acid; Glutamine; Intracellular Fluid; Lactic Acid; Mice; Pyruvic Acid | 2001 |
Inhibiting 3-phosphoglycerate kinase by EDTA stimulates the development of the cleavage stage mouse embryo.
Topics: Animals; Blastocyst; Cell Survival; Cells, Cultured; Chelating Agents; Cleavage Stage, Ovum; Edetic Acid; Embryonic and Fetal Development; Enzyme Inhibitors; Female; Glucose; Glutamine; Glycolysis; Magnesium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Phosphoglycerate Kinase; Pregnancy; Pyruvic Acid; Triazines | 2001 |
Vero cells, but not oviductal cells, increase the hatching frequency and total cell count of mouse blastocysts partly by changing energy substrate concentrations in culture medium.
Topics: Animals; Blastocyst; Chlorocebus aethiops; Coculture Techniques; Culture Media, Conditioned; Embryonic and Fetal Development; Fallopian Tubes; Female; Glutamine; Humans; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Pyruvic Acid; Vero Cells | 2001 |
Fetal hepatic and umbilical uptakes of glucogenic substrates during a glucagon-somatostatin infusion.
Topics: Alanine; Animals; Arginine; Blood Glucose; Female; Fetal Blood; Gestational Age; Glucagon; Gluconeogenesis; Glucose; Glutamine; Lactic Acid; Liver; Ornithine; Oxygen Consumption; Placenta; Pregnancy; Pyruvic Acid; Sheep; Somatostatin; Umbilical Veins | 2002 |
Use of energy substrates by various stage preimplantation pig embryos produced in vivo and in vitro.
Topics: Analysis of Variance; Animals; Blastocyst; Cell Survival; Cells, Cultured; Citric Acid Cycle; Female; Fertilization in Vitro; Gestational Age; Glucose; Glutamine; Pregnancy; Pyruvic Acid; Swine | 2002 |
Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1'S,2'R)-2-(carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy.
Topics: Amino Acid Transport System X-AG; Amino Acids, Dicarboxylic; Animals; Carbon Isotopes; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Guinea Pigs; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Molecular Conformation; Oocytes; Pyruvate Carboxylase; Pyruvic Acid; Xenopus laevis | 2002 |
Amino acid kinetics during the anhepatic phase of liver transplantation.
Topics: Alanine; Amino Acids; Blood Glucose; Carbon Dioxide; Carbon Isotopes; Deuterium; Electrolytes; Fatty Acids, Nonesterified; Gluconeogenesis; Glutamine; Glycerol; Hematocrit; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Leucine; Liver; Liver Transplantation; Metabolic Clearance Rate; Middle Aged; Nitrogen; Oxygen; Pyruvic Acid | 2002 |
Hepatic gluconeogenic capacity from various precursors in young versus old rats.
Topics: Aging; Alanine; Animals; Body Weight; Cell Separation; Cell Survival; Dihydroxyacetone; Fasting; Fructose; Gluconeogenesis; Glucose; Glutamine; Glycerol; Glycogen; Hepatocytes; Lactic Acid; Liver; Male; Oxaloacetates; Pyruvic Acid; Rats; Rats, Inbred F344 | 2002 |
Time-dependence of the contribution of pyruvate carboxylase versus pyruvate dehydrogenase to rat brain glutamine labelling from [1-(13) C]glucose metabolism.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Female; Glucose; Glutamine; Infusions, Intravenous; Magnetic Resonance Spectroscopy; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Wistar | 2002 |
Purinergic regulation of glucose and glutamine synthesis in isolated rabbit kidney-cortex tubules.
Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Ammonium Chloride; Animals; Aspartic Acid; Calcium Signaling; Cyclic AMP; Dose-Response Relationship, Drug; Fructose-Bisphosphatase; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hypoxanthine; In Vitro Techniques; Inosine; Kidney Tubules; Ligands; Male; Phosphorylation; Pyruvic Acid; Rabbits; Signal Transduction | 2002 |
Glutamine cycling in isolated working rat heart.
Topics: Adaptation, Physiological; Animals; Cardiac Output; Glucose; Glutamic Acid; Glutamine; Heart; In Vitro Techniques; Insulin; Male; Myocardium; Oxygen Consumption; Propionates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sodium Acetate; Substrate Cycling | 2003 |
Retinal function loss after monocarboxylate transport inhibition.
Topics: Alanine; Animals; Coumaric Acids; Dark Adaptation; Electroretinography; Enzyme Inhibitors; Glutamine; Interneurons; Ketoglutaric Acids; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Rats, Long-Evans; Retina; Succinic Acid; Vision, Ocular | 2004 |
Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Chromatography, Affinity; Cystathionine beta-Synthase; Glutamine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Nickel; Phenylalanine; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 2004 |
Survival and growth of goat primordial follicles after in vitro culture of ovarian cortical slices in media containing coconut water.
Topics: Animals; Cell Division; Cocos; Culture Media; Culture Techniques; Female; Glutamine; Goats; Granulosa Cells; Hypoxanthine; Insulin; Ovarian Follicle; Ovary; Pyruvic Acid; Selenium; Serum Albumin, Bovine; Solutions; Transferrin; Water | 2004 |
13C NMR isotopomer analysis of anaplerotic pathways in INS-1 cells.
Topics: Adenosine Triphosphate; Animals; Carbon; Carbon Isotopes; Cell Line; Citric Acid Cycle; Culture Media; Glucose; Glutamate Dehydrogenase; Glutamic Acid; Glutamine; Glycolysis; Humans; Insulin; Insulin Secretion; Leucine; Magnetic Resonance Spectroscopy; Models, Biological; Oxygen; Perfusion; Protons; Pyruvate Carboxylase; Pyruvic Acid; Rats; Time Factors | 2004 |
Studies on the mechanism of nitrogen storage; the effects of anterior pituitary growth hormone preparations on the pyruvate-activated deamidation of glutamine in liver tissue.
Topics: Glutamine; Growth Hormone; Humans; Liver; Nitrogen; Pituitary Gland; Pituitary Hormones; Pyruvates; Pyruvic Acid | 1949 |
Ammonia effects on pyruvate/lactate production in astrocytes--interaction with glutamate.
Topics: Ammonia; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bucladesine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Energy Metabolism; Glutamic Acid; Glutamine; Glutathione; Glycolysis; Hyperammonemia; Interneurons; Lactic Acid; Malates; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Pyruvic Acid; Up-Regulation | 2005 |
Effects of culture media and energy sources on the inhibition of nuclear maturation in bovine oocytes.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Culture Media; Dose-Response Relationship, Drug; Female; Glucose; Glutamine; Hypoxanthine; Lactic Acid; Meiosis; Oocytes; Pyruvic Acid; Species Specificity | 2006 |
Folate synthesis in plants: purification, kinetic properties, and inhibition of aminodeoxychorismate synthase.
Topics: 4-Aminobenzoic Acid; Arabidopsis Proteins; Carbon-Nitrogen Ligases; Chorismic Acid; Escherichia coli; Folic Acid; Glutamine; Kinetics; Methotrexate; Pyruvic Acid; Recombinant Fusion Proteins; Substrate Specificity; Transaminases | 2006 |
Adenine nucleotide pattern in rat pancreatic islets exposed to nutrient secretagogues.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Female; Galactose; Glucose; Glutamine; Glyceraldehyde; Islets of Langerhans; Keto Acids; Lactic Acid; Leucine; Mannose; Nutritional Physiological Phenomena; Pyruvic Acid; Rats; Rats, Wistar | 2006 |
Towards industrial application of quasi real-time metabolic flux analysis for mammalian cell culture.
Topics: Animals; Bioreactors; Biotechnology; Cell Culture Techniques; CHO Cells; Citrate (si)-Synthase; Citric Acid Cycle; Cricetinae; Cricetulus; Glucose; Glutamine; Ketone Oxidoreductases; Lactic Acid; Models, Biological; Pyruvate Kinase; Pyruvic Acid; Signal Transduction | 2006 |
Requirement for, and patterns of, pyruvate and glutamine metabolism in the domestic dog oocyte in vitro.
Topics: Animals; Cats; Cell Nucleus; Cells, Cultured; Culture Media; Dogs; Energy Metabolism; Female; Glutamine; Humans; Meiosis; Oocytes; Oxidation-Reduction; Pyruvic Acid | 2007 |
Cerebral glutamine and glutamate levels in relation to compromised energy metabolism: a microdialysis study in subarachnoid hemorrhage patients.
Topics: Astrocytes; Brain; Energy Metabolism; Female; Glutamic Acid; Glutamine; Humans; Lactic Acid; Male; Microdialysis; Neurons; Pyruvic Acid; Subarachnoid Hemorrhage | 2007 |
Improving culture conditions for temporomandibular joint disc tissue engineering.
Topics: Animals; Bioreactors; Cattle; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Coculture Techniques; Collagen Type I; Compressive Strength; Culture Media; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation; Glutamine; Glycosaminoglycans; Growth Substances; Hypoglycemic Agents; Insulin; Proline; Pyruvic Acid; Reference Standards; Swine; Temporomandibular Joint Disc; Tensile Strength; Time Factors; Tissue Engineering | 2007 |
Oxidation of (14)C-labeled compounds perfused by microdialysis in the brains of free-moving rats.
Topics: Animals; Behavior, Animal; Brain; Carbon Radioisotopes; Citric Acid Cycle; Coumaric Acids; Glutamic Acid; Glutamine; Lactates; Microdialysis; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Wakefulness | 2007 |
Combining metabolic flux analysis tools and 13C NMR to estimate intracellular fluxes of cultured astrocytes.
Topics: Animals; Astrocytes; Brain; Brain Chemistry; Carbon Isotopes; Cells, Cultured; Citric Acid Cycle; Energy Metabolism; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Intracellular Fluid; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Neurochemistry; Oxidative Phosphorylation; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Pyruvic Acid | 2008 |
Cerebral glutamine concentration and lactate-pyruvate ratio in patients with acute liver failure.
Topics: Adolescent; Adult; Aged; Astrocytes; Brain; Brain Edema; Critical Care; Female; Glutamine; Humans; Hyperammonemia; Intracranial Hypertension; Lactic Acid; Liver Failure, Acute; Male; Microdialysis; Middle Aged; Mitochondria; Pyruvic Acid; Severity of Illness Index | 2008 |
The role of a conserved histidine residue in a pyruvate-specific Class II aldolase.
Topics: Alanine; Aldehyde-Lyases; Amino Acid Sequence; Amino Acid Substitution; Conserved Sequence; Escherichia coli Proteins; Evolution, Molecular; Glutamine; Histidine; Mutation; Protein Conformation; Pyruvic Acid | 2008 |
Evidence that L-glutamine is better than L-alanine as gluconeogenic substrate in perfused liver of weaned fasted rats submitted to short-term insulin-induced hypoglycaemia.
Topics: Alanine; Animals; Fasting; Gluconeogenesis; Glucose; Glutamine; Glycerol; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Time Factors; Weaning | 2009 |
Glutamate is the major anaplerotic substrate in the tricarboxylic acid cycle of isolated rumen epithelial and duodenal mucosal cells from beef cattle.
Topics: Animals; Carbon Isotopes; Cattle; Citric Acid Cycle; Diet; Duodenum; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Glucose; Glutamic Acid; Glutamine; Intestinal Mucosa; Lactic Acid; Leucine; Male; Pyruvic Acid; Rumen; Valine | 2009 |
Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets.
Topics: Adenosine Triphosphate; Animals; Base Sequence; Cell Line; Diabetes Mellitus, Type 2; DNA Primers; Female; Glucose; Glucose Transporter Type 2; Glutamine; Glycolysis; Hepatocyte Nuclear Factor 1-alpha; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Mice; Mice, Knockout; Mitochondria; Mutation; Oxidative Phosphorylation; Pyruvic Acid; Rats; RNA, Messenger | 2009 |
Role of Aggregatibacter actinomycetemcomitans in glutathione catabolism.
Topics: Aggregatibacter actinomycetemcomitans; Ammonia; Bacteroides; Cloning, Molecular; Cystathionine gamma-Lyase; Dipeptidases; Dipeptides; Escherichia coli; Eubacterium; gamma-Glutamyltransferase; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutamine; Glutathione; Humans; Hydrogen Sulfide; Hydrogen-Ion Concentration; Mass Spectrometry; Plasmids; Polymerase Chain Reaction; Porphyromonas gingivalis; Pyruvic Acid; Sequence Analysis, DNA; Sulfhydryl Compounds; Temperature; Time Factors; Treponema denticola | 2009 |
Relationship between intracranial hemodynamics and microdialysis markers of energy metabolism and glutamate-glutamine turnover in patients with subarachnoid hemorrhage. Clinical article.
Topics: Aged; Biomarkers; Blood Pressure; Cerebrovascular Circulation; Critical Care; Energy Metabolism; Female; Glutamic Acid; Glutamine; Hemodynamics; Humans; Intracranial Pressure; Lactic Acid; Male; Microdialysis; Middle Aged; Prospective Studies; Pyruvic Acid; Retrospective Studies; Subarachnoid Hemorrhage | 2009 |
Pre-ischemic treatment with memantine reversed the neurochemical and behavioural parameters but not energy metabolites in middle cerebral artery occluded rats.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Brain; Glutamate-Ammonia Ligase; Glutamine; Glutathione; Lactic Acid; Male; Memantine; Middle Cerebral Artery; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase | 2009 |
Hepatic anaplerotic outflow fluxes are redirected from gluconeogenesis to lactate synthesis in patients with Type 1a glycogen storage disease.
Topics: Acetyl Coenzyme A; Adolescent; Carbon Isotopes; Child; Citric Acid Cycle; Female; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Glutamine; Glycerol; Glycogen Storage Disease Type I; Humans; Lactates; Liver; Male; Pyruvic Acid; Young Adult | 2009 |
Glutamate metabolic pathways and retinal function.
Topics: Animals; Aspartate Aminotransferases; Electroretinography; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Homeostasis; Immunohistochemistry; Ketoglutaric Acids; Lactic Acid; Methionine Sulfoximine; Photoreceptor Cells, Vertebrate; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Succinic Acid; Synaptic Transmission; Vision, Ocular | 2009 |
Glutamine metabolism is essential for human cytomegalovirus infection.
Topics: Adenosine Triphosphate; Ammonia; Cell Survival; Cells, Cultured; Citric Acid Cycle; Cytomegalovirus; Cytomegalovirus Infections; Fibroblasts; Glucose; Glutamate Dehydrogenase; Glutaminase; Glutamine; Glycolysis; Humans; Kinetics; Pyruvic Acid | 2010 |
Role of GlnR in acid-mediated repression of genes encoding proteins involved in glutamine and glutamate metabolism in Streptococcus mutans.
Topics: Acids; Adenosine Triphosphate; Anti-Bacterial Agents; Bacterial Proteins; Citric Acid; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glutamic Acid; Glutamine; Hydrogen; Metabolic Networks and Pathways; Microbial Viability; Multigene Family; Oligonucleotide Array Sequence Analysis; Pyruvic Acid; Regulon; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus mutans | 2010 |
Enzymatic desamidation of glutamine in the presence of pyruvate furnished by concomitant reactions.
Topics: Amino Acids; Enzymes; Glutamine; Pyruvates; Pyruvic Acid | 1947 |
Studies on the effect of pyruvate on the desamidation of glutamine, asparagine, and related compounds.
Topics: Amino Acids; Asparagine; Enzymes; Glutamine; Pyruvates; Pyruvic Acid | 1947 |
Relation between pH and the effect of pyruvate on the desamidation of glutamine and asparagine.
Topics: Amino Acids; Asparagine; Biochemical Phenomena; Glutamine; Hydrogen-Ion Concentration; Pyruvates; Pyruvic Acid | 1947 |
Brain glutamine synthesis requires neuronal-born aspartate as amino donor for glial glutamate formation.
Topics: Alanine; Animals; Aspartic Acid; Astrocytes; Brain Chemistry; Cells, Cultured; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Immunohistochemistry; Lactic Acid; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron; Neurons; Nitrogen; Pyruvic Acid | 2011 |
Glutamine effect on cultured granule neuron death induced by glucose deprivation and chemical hypoxia.
Topics: Animals; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebellum; Glucose; Glutamine; Membrane Potentials; Mitochondria; Neurons; Pyruvic Acid; Rats; Rats, Wistar; Receptors, Ionotropic Glutamate | 2010 |
Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis.
Topics: Biomass; Bioreactors; Brain; Cell Count; Cell Culture Techniques; Cell Line; Citric Acid Cycle; Culture Media; Glucose; Glutamine; Glycolysis; Humans; Kinetics; Models, Biological; Pyruvic Acid | 2011 |
Estimation of intracellular fluxes in cerebellar neurons after hypoglycemia: importance of the pyruvate recycling pathway and glutamine oxidation.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Glucose; Glutamic Acid; Glutamine; Glycolysis; Hypoglycemia; Intracellular Fluid; Lactic Acid; Mice; Neural Pathways; Neurons; Oxidation-Reduction; Pyruvic Acid | 2011 |
Pyruvate carboxylase is required for glutamine-independent growth of tumor cells.
Topics: Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Glioblastoma; Glutaminase; Glutamine; Humans; Pyruvate Carboxylase; Pyruvic Acid | 2011 |
Viruses and metabolism: alterations of glucose and glutamine metabolism mediated by human cytomegalovirus.
Topics: Cell Line, Tumor; Cytomegalovirus; Endoplasmic Reticulum; Fatty Acids; Glucose; Glutamine; Host-Pathogen Interactions; Humans; Ketoglutaric Acids; Pyruvic Acid; Signal Transduction; Tricarboxylic Acids | 2011 |
Photoperiodic regulation of glycogen metabolism, glycolysis, and glutamine synthesis in tanycytes of the Siberian hamster suggests novel roles of tanycytes in hypothalamic function.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Carbohydrate Metabolism; Cloning, Molecular; Cricetinae; DNA, Complementary; Ependyma; Glucose; Glutamic Acid; Glutamine; Glycogen; Glycolysis; Hypothalamus; In Situ Hybridization; Lactic Acid; Male; Microscopy, Electron; Neuropil; Phodopus; Photoperiod; Pyruvic Acid | 2011 |
Primary metabolism in the new human cell line AGE1.HN at various substrate levels: increased metabolic efficiency and α1-antitrypsin production at reduced pyruvate load.
Topics: alpha 1-Antitrypsin; Cell Line; Cell Proliferation; Cell Survival; Culture Media; Glucose; Glutamine; Humans; Neurons; Pyruvic Acid | 2012 |
Measuring multiple neurochemicals and related metabolites in blood and brain of the rhesus monkey by using dual microdialysis sampling and capillary hydrophilic interaction chromatography-mass spectrometry.
Topics: Acetylcholine; Animals; Blood Chemical Analysis; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Macaca mulatta; Mass Spectrometry; Microdialysis; Pyruvic Acid | 2012 |
Absence of glutamine supplementation prevents differentiation of murine calvarial osteoblasts to a mineralizing phenotype.
Topics: Animals; Calcification, Physiologic; Cell Differentiation; Cells, Cultured; Glutamine; Humans; Mice; Mice, Inbred C57BL; Osteoblasts; Osteocalcin; Phenotype; Pyruvic Acid; Skull | 2011 |
Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Antibiotics, Antineoplastic; Carbon Isotopes; Cell Line; Cell Survival; Citric Acid Cycle; Dose-Response Relationship, Drug; Doxorubicin; Energy Metabolism; Glucose; Glutamine; Glycolysis; Lactic Acid; Mice; Myocytes, Cardiac; Oxidation-Reduction; Pyruvic Acid; Time Factors | 2012 |
Rat brain slices oxidize glucose at high rates: a (13)C NMR study.
Topics: Acetates; Anesthesia; Anesthetics; Animals; Aspartic Acid; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Rats; Rats, Wistar | 2011 |
The ability to achieve meiotic maturation in the dog oocyte is linked to glycolysis and glutamine oxidation.
Topics: Animals; Cells, Cultured; Dogs; Female; Glucose; Glutamine; Glycolysis; Meiosis; Oocytes; Oogenesis; Ovarian Follicle; Pyruvic Acid | 2012 |
The effect of fractionated plasma separation and adsorption on cerebral amino acid metabolism and oxidative metabolism during acute liver failure.
Topics: Adult; Amino Acids; Cerebrum; Dialysis Solutions; Extracorporeal Circulation; Female; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Male; Microdialysis; Middle Aged; Pyruvic Acid; Sorption Detoxification; Statistics, Nonparametric | 2012 |
Heptanoate as a neural fuel: energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain.
Topics: Acetyl Coenzyme A; Animals; Anticonvulsants; Brain; Brain Chemistry; Energy Metabolism; Glucose; Glucose Transporter Type 1; Glutamine; Heptanoates; Magnetic Resonance Spectroscopy; Mice; Mice, Transgenic; Pyruvic Acid; Seizures; Triglycerides | 2013 |
Histone acetylation regulates intracellular pH.
Topics: Acetates; Acetylation; Carbohydrate Metabolism; Chromatin; Gene Expression Regulation; Glucose; Glutamine; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydrogen-Ion Concentration; Hydroxamic Acids; Intracellular Fluid; Monocarboxylic Acid Transporters; Niacinamide; Protein Processing, Post-Translational; Pyruvic Acid; Sequence Analysis, RNA; Transcriptome | 2013 |
Metabolic effects of glutamine on the heart: anaplerosis versus the hexosamine biosynthetic pathway.
Topics: Animals; Biosynthetic Pathways; Energy Metabolism; Fatty Acids; Glutamine; Heart; Hexosamines; In Vitro Techniques; Male; Myocardium; Oxidation-Reduction; Pyruvic Acid; Rats | 2013 |
Inhibitory effect of tumor necrosis factor α on gluconeogenesis in perfused rat liver.
Topics: Alanine; Animals; Area Under Curve; Gluconeogenesis; Glucose; Glutamine; Glycerol; Lactic Acid; Liver; Male; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Urea | 2013 |
Metabolomic analysis of cerebrospinal fluid indicates iron deficiency compromises cerebral energy metabolism in the infant monkey.
Topics: Anemia, Iron-Deficiency; Animals; Brain; Citric Acid; Energy Metabolism; Female; Glutamine; Iron Deficiencies; Lactic Acid; Macaca mulatta; Magnetic Resonance Imaging; Metabolomics; Pyruvic Acid | 2013 |
Neuron-astrocyte interactions, pyruvate carboxylation and the pentose phosphate pathway in the neonatal rat brain.
Topics: Animals; Animals, Newborn; Astrocytes; Brain; Glutamic Acid; Glutamine; Neurons; Neurotransmitter Agents; Pentose Phosphate Pathway; Pyruvate Carboxylase; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2014 |
Modeling of brain metabolism and pyruvate compartmentation using (13)C NMR in vivo: caution required.
Topics: Animals; Brain Chemistry; Carbon Radioisotopes; Citric Acid Cycle; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; Models, Statistical; Neuroglia; Neurons; Pyruvic Acid; Rats | 2013 |
Cerebral microdialysis reflects the neuroprotective effect of fractionated plasma separation and adsorption in acute liver failure better and earlier than intracranial pressure: a controlled study in pigs.
Topics: Ammonia; Animals; Brain Edema; Cerebrum; Extracorporeal Circulation; Glucose; Glutamic Acid; Glutamine; Intracranial Hypertension; Intracranial Pressure; Lactic Acid; Liver Failure, Acute; Microdialysis; Pyruvic Acid; Sorption Detoxification; Swine; Time Factors | 2013 |
Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling.
Topics: Animals; Apoptosis; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Respiration; Energy Metabolism; Galactose; Glucose; Glutamine; Glycolysis; HCT116 Cells; Humans; Mice; Mitochondria; Neoplasms; Oxidative Phosphorylation; Oxygen Consumption; PC12 Cells; Pyruvic Acid; Rats; Substrate Specificity | 2014 |
Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Citric Acid Cycle; Glutamine; Humans; Leukemia; Liver Neoplasms, Experimental; Melanoma; Metabolic Networks and Pathways; Mitosis; NADP; Neoplastic Stem Cells; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar; Tetrahydrofolates | 2014 |
Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cell Line, Tumor; Cytosol; Glucose; Glutamine; Islets of Langerhans; Leucine; Membrane Potentials; Mice; Mitochondria; Pyruvic Acid; Sweetening Agents | 2014 |
Serum 1H-NMR metabolomic fingerprints of acute-on-chronic liver failure in intensive care unit patients with alcoholic cirrhosis.
Topics: Biomarkers; Creatinine; Glutamine; Humans; Intensive Care Units; Ketone Bodies; Lactic Acid; Liver Cirrhosis, Alcoholic; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Metabolome; Multivariate Analysis; Phenylalanine; Pyruvic Acid; Tyrosine | 2014 |
Neuronal and astrocytic metabolism in a transgenic rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Astrocytes; Brain; Citric Acid Cycle; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Neurons; Pyruvic Acid; Rats; Rats, Transgenic; Rats, Wistar | 2014 |
Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.
Topics: Acetyl Coenzyme A; Animals; Antineoplastic Agents; Biological Transport; Catechin; Cell Line, Tumor; Cell Survival; Citric Acid; Citric Acid Cycle; Coumaric Acids; Glucose; Glutamine; Humans; Lipid Metabolism; Male; Mice, Nude; Mitochondria; Oxidation-Reduction; Pyruvic Acid; Sugar Alcohol Dehydrogenases; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
Regulation of substrate utilization by the mitochondrial pyruvate carrier.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Fatty Acids; Glutamine; Humans; Lipogenesis; Metabolic Flux Analysis; Mice; Muscle Fibers, Skeletal; Oxidation-Reduction; Proprotein Convertase 1; Proprotein Convertase 2; Pyruvic Acid | 2014 |
Mitochondrial malic enzyme 3 is important for insulin secretion in pancreatic β-cells.
Topics: Animals; Base Sequence; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; Glucose; Glutamine; Immunoblotting; Insulin; Insulin Secretion; Insulin-Secreting Cells; Leucine; Malate Dehydrogenase; Mitochondria; Pyruvic Acid; Rats; RNA, Messenger; RNA, Small Interfering | 2015 |
Metabolomic Analysis Reveals Increased Aerobic Glycolysis and Amino Acid Deficit in a Cellular Model of Amyotrophic Lateral Sclerosis.
Topics: Aerobiosis; Alanine; Amino Acids; Amyotrophic Lateral Sclerosis; Animals; Caspase 3; Caspase 7; Cell Death; Cell Line; Culture Media, Serum-Free; Glucose; Glutamine; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactates; Metabolome; Metabolomics; Mice; Models, Biological; Mutant Proteins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid; Superoxide Dismutase | 2016 |
Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis.
Topics: Acrylates; Animals; Cells, Cultured; Citric Acid Cycle; Diet, High-Fat; Gluconeogenesis; Glucose; Glutamine; Glycogen; Hepatocytes; Hyperglycemia; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; Obesity; Proprotein Convertase 1; Proprotein Convertase 2; Pyruvic Acid; Triglycerides | 2015 |
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth.
Topics: Adaptation, Physiological; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Gene Expression Regulation, Neoplastic; Gluconeogenesis; Glucose; Glutamine; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Mitochondria; Neoplasms; Phosphoenolpyruvate; Phosphoenolpyruvate Carboxykinase (ATP); Purines; Pyruvic Acid; Serine | 2015 |
Glutamine Oxidation Is Indispensable for Survival of Human Pluripotent Stem Cells.
Topics: Adenosine Triphosphate; Cell Line; Cell Survival; Citric Acid Cycle; Glucose; Glutamine; Glycolysis; Humans; Oxidation-Reduction; Pluripotent Stem Cells; Pyruvic Acid | 2016 |
Differentiation-Dependent Energy Production and Metabolite Utilization: A Comparative Study on Neural Stem Cells, Neurons, and Astrocytes.
Topics: 3-Hydroxybutyric Acid; Animals; Astrocytes; Cell Differentiation; Cell Line; Cell Respiration; Energy Metabolism; Glucose; Glutamine; Lactates; Metabolome; Mice; Mitochondria; Neural Stem Cells; Neurons; Oxygen Consumption; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvic Acid | 2016 |
Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.
Topics: Animals; Anion Transport Proteins; Citric Acid Cycle; Diet, Ketogenic; Female; Fibroblasts; Genes, Lethal; Glucose; Glutamine; Mice; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Pregnancy; Pyruvic Acid | 2016 |
Glucose-dependent anaplerosis in cancer cells is required for cellular redox balance in the absence of glutamine.
Topics: Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Citric Acid Cycle; Glucose; Glutamine; Glutathione; Humans; Neoplasms; Oxidation-Reduction; Pyruvic Acid; Reactive Oxygen Species | 2016 |
Metabolic fate of glucose in rats with traumatic brain injury and pyruvate or glucose treatments: A NMR spectroscopy study.
Topics: Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Glucose; Glutamic Acid; Glutamine; Magnetic Resonance Imaging; Male; Pyruvic Acid; Rats, Sprague-Dawley | 2017 |
Amniotic Fluid and Maternal Serum Metabolic Signatures in the Second Trimester Associated with Preterm Delivery.
Topics: Adult; Amniocentesis; Amniotic Fluid; Biomarkers; Case-Control Studies; Female; Gestational Age; Glutamic Acid; Glutamine; Humans; Infant, Newborn; Lipids; Metabolome; Obstetric Labor, Premature; Pregnancy; Pregnancy Trimester, Second; Principal Component Analysis; Prognosis; Pyruvic Acid | 2017 |
Alpha-Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction.
Topics: Adipocytes; Aging; Animals; Animals, Newborn; Cell Death; Cell Differentiation; Chondrocytes; Chromatin; Gene Expression Regulation; Glutamine; Histones; Hypoxia-Inducible Factor 1, alpha Subunit; Ketoglutaric Acids; Mesenchymal Stem Cells; Metabolome; Mice; Mice, Knockout; Mitochondria; Osteoblasts; Primary Cell Culture; Pyruvic Acid; Reactive Oxygen Species; Skin; Superoxide Dismutase | 2017 |
Mixing of water masses caused by a drifting iceberg affects bacterial activity, community composition and substrate utilization capability in the Southern Ocean.
Topics: Acetylglucosamine; Antarctic Regions; Aquatic Organisms; Archaea; Bacteria; Carbon; Ecosystem; Global Warming; Glutamine; Ice Cover; Microbiota; Plankton; Pyruvic Acid; Seasons; Water Microbiology | 2017 |
Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species.
Topics: Acetoacetates; Adenosine Triphosphate; Adipocytes; Aerobiosis; Anaerobiosis; Biomarkers; Cell Differentiation; Chondrocytes; Energy Metabolism; Glucose; Glutamine; Glycolysis; Humans; Iridoids; Mesenchymal Stem Cells; Osteocytes; Oxidation-Reduction; Oxidative Stress; Pyruvic Acid; Reactive Oxygen Species; Uncoupling Protein 2 | 2017 |
Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria.
Topics: Animals; Cell Line; Cell Line, Tumor; Electron-Transferring Flavoproteins; Energy Metabolism; Gene Expression Regulation, Enzymologic; Glucose; Glutamine; Humans; Kinetics; Mice; Mitochondria; Mitochondria, Liver; Mitochondria, Muscle; Organ Specificity; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Palmitic Acid; Pyruvic Acid | 2017 |
Metabolic engineering of CHO cells for the development of a robust protein production platform.
Topics: Animals; Antibodies, Monoclonal; Bioreactors; Carbon; CHO Cells; Citric Acid Cycle; Cricetinae; Cricetulus; Cytoplasm; Cytosol; Energy Metabolism; Gene Dosage; Glucose; Glutamine; Glycosylation; Lactates; Lactic Acid; Metabolic Engineering; Mitochondria; Oligonucleotides; Oxidation-Reduction; Polysaccharides; Pyruvate Carboxylase; Pyruvic Acid; Saccharomyces cerevisiae | 2017 |
Xanthurenic Acid Formation from 3-Hydroxykynurenine in the Mammalian Brain: Neurochemical Characterization and Physiological Effects.
Topics: Aged; Animals; Brain; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fluoroquinolones; Glucose; Glutamine; Humans; In Vitro Techniques; Kynurenine; Male; Mice; Middle Aged; Piperazines; Postmortem Changes; Pyruvic Acid; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tacrolimus; Temperature; Tissue Distribution; Transaminases; Veratridine; Xanthurenates | 2017 |
Rubella Viruses Shift Cellular Bioenergetics to a More Oxidative and Glycolytic Phenotype with a Strain-Specific Requirement for Glutamine.
Topics: A549 Cells; Endothelial Cells; Energy Metabolism; Glucose; Glutamine; Glycolysis; Homeostasis; Humans; Kynurenine; Metabolic Networks and Pathways; Mitochondria; Nucleotides; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Phenotype; Pyruvic Acid; Rubella virus; Virus Replication | 2018 |
Comparison of the effects of metformin on MDA-MB-231 breast cancer cells in a monolayer culture and in tumor spheroids as a function of nutrient concentrations.
Topics: AMP-Activated Protein Kinases; Cell Culture Techniques; Cell Survival; Enzyme Activation; Female; Glucose; Glutamine; Humans; Hypoglycemic Agents; Metformin; Nutrients; Pyruvic Acid; Spheroids, Cellular; Triple Negative Breast Neoplasms; Tumor Microenvironment | 2019 |
Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.
Topics: Animals; Biological Transport; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glutamine; Humans; Male; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Binding; Pyruvic Acid; Receptors, Androgen; Signal Transduction | 2019 |
Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; ERRalpha Estrogen-Related Receptor; Female; Gene Expression Regulation, Neoplastic; Glucosephosphate Dehydrogenase; Glutaminase; Glutamine; Glycolysis; Homeostasis; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvic Acid; Receptors, Estrogen; Tumor Cells, Cultured | 2019 |
Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis.
Topics: Animals; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Citric Acid Cycle; Glutamine; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Mice, Inbred C57BL; Mitochondria; Neoplasm Proteins; Organ Specificity; Pyruvic Acid; Transcriptome | 2019 |
The heterocyclic compound Tempol inhibits the growth of cancer cells by interfering with glutamine metabolism.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cyclic N-Oxides; Female; Glutamine; Glycolysis; Heterocyclic Compounds; Humans; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Docking Simulation; NAD; Neoplasms; Oxidative Phosphorylation; Pyruvic Acid; Reactive Oxygen Species; Serine; Spin Labels; Xenograft Model Antitumor Assays | 2020 |
Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer.
Topics: Benzeneacetamides; Cell Proliferation; Drug Resistance, Neoplasm; Female; Glutaminase; Glutamine; Humans; Pyruvic Acid; Thiadiazoles; Triple Negative Breast Neoplasms; Tumor Cells, Cultured; Tumor Microenvironment | 2020 |
The Growth Response to Beta-Hydroxybutyrate in SH-SY5Y Neuroblastoma Cells is Suppressed by Glucose and Pyruvate Supplementation.
Topics: 3-Hydroxybutyric Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Culture Media; Glucose; Glutamine; Humans; Pyruvic Acid | 2021 |
Elongation factor eEF2 kinase and autophagy jointly promote survival of cancer cells.
Topics: A549 Cells; Autophagy; Cell Line, Tumor; Cell Survival; Elongation Factor 2 Kinase; Energy Metabolism; Gene Expression Regulation, Neoplastic; Glucose; Glutamine; Humans; Macrolides; Microtubule-Associated Proteins; PC-3 Cells; Phosphoproteins; Protein Biosynthesis; Proteome; Proteomics; Pyruvic Acid; Sequestosome-1 Protein; Signal Transduction | 2021 |
Pyruvate and Glutamine Define the Effects of Cholecystokinin and Ethanol on Mitochondrial Oxidation, Necrosis, and Morphology of Rat Pancreatic Acini.
Topics: Acinar Cells; Amylases; Animals; Cell Survival; Cells, Cultured; Cholecystokinin; Ethanol; Glutamine; Male; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria; Necrosis; Oxidation-Reduction; Oxygen Consumption; Pancreas; Pyruvic Acid; Rats, Wistar | 2021 |
Identification and characterization of novel MPC1 gene variants causing mitochondrial pyruvate carrier deficiency.
Topics: Glutamine; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Pyruvic Acid | 2022 |
Rewired Cellular Metabolic Profiles in Response to Metformin under Different Oxygen and Nutrient Conditions.
Topics: Cell Line, Tumor; Cell Proliferation; Culture Media; Glucose; Glutamine; HeLa Cells; Humans; Lactic Acid; Metabolomics; Metformin; NAD; Oxygen; Pyruvic Acid; Tumor Hypoxia | 2022 |
Elongating porcine conceptuses can utilize glutaminolysis as an anaplerotic pathway to maintain the TCA cycle†.
Topics: Animals; Carbon Isotopes; Female; Glucose; Glutamic Acid; Glutamine; Ketoglutaric Acids; Pregnancy; Pyruvic Acid; Swine | 2022 |
Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4+ T-cell proliferation and glycolytic activity under hypoxia and normoxia.
Topics: Amino Acids; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; Cell Proliferation; Glucose; Glutamic Acid; Glutaminase; Glutamine; Humans; Hypoxia; Oxygen; Pyruvic Acid | 2022 |
Genome-Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment.
Topics: Animals; Carcinoma, Hepatocellular; CRISPR-Cas Systems; Early Detection of Cancer; Glutamine; Liver Neoplasms; Mice; Mice, Knockout; Oxidoreductases; Pyruvic Acid | 2022 |