glutamine and proglumide

glutamine has been researched along with proglumide in 166 studies

Research

Studies (166)

TimeframeStudies, this research(%)All Research%
pre-1990146 (87.95)18.7374
1990's19 (11.45)18.2507
2000's1 (0.60)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bouletreau, P; Motin, J; Petit, P1
Bignamini, AA; Cacioli, D; Casula, PL; Ferrante, F; Galeone, M; Moise, G1
Vasilevskaia, LS1
Lada-Jagas, R1
Fossati, C1
Kutz, K; Lindstaedt, H; Mayershofer, R; Miederer, SE1
Bennani, A1
Bignamini, AA; Casula, PL; Rovati, AL1
Sambin, P; Trepo, C1
Bali, JP; Balmes, JL; Boucard, M; Cayrol, B; Marignan, R; Pham, TN; Tubiana, M1
Kutz, K; Lindstaedt, H; Miederer, SE; Wuttke, H1
Pipitone, V1
Rovati, AL1
Bleichner, G1
Desvigne, A; Desvigne, C; Faivre, M; Vagne, M1
Suh, HH; Tseng, LF1
Bodnar, RJ; Pasternak, GW; Paul, D1
Baba, S; Fujii, M; Fujisawa, T; Hasegawa, H; Koide, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S1
Nagy, I; Pap, A; Takács, T; Varró, V2
Biliotti, D; Bontempo, I; Corazziari, E; De Medici, A; Pallotta, N; Ricci, R; Torsoli, A1
Douglas, BR; Jansen, JB; Lamers, CB; Rovati, LC; Woutersen, RA1
Hashimoto, T; MacLellan, DG; Poston, GJ; Thompson, JC; Townsend, CM; Upp, JR1
Beglinger, C; Gyr, K; Hildebrand, P; Jansen, JB; Lamers, CB; Rovati, LC; Setnikar, I; Stalder, GA; Zuercher, M1
Bonato, C; De Fazio, C; Festorazzi, S; Malesci, A; Rovati, L; Setnikar, I; Tacconi, M; Valentini, A1
Baba, H; Fujimura, M; Toda, N1
Fujii, M; Itoh, H; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S1
Douglas, BR; Jansen, JB; Jebbink, MC; Lamers, CB1
Kellstein, DE; Mayer, DJ1
Liu, Y; Xu, QZ; Zhang, J2
Jansen, JB; Jebbink, MC; Lamers, CB; Masclee, AA1
Bastié, MJ; Pradayrol, L; Scemama, JL; Seva, C; Vaysse, N1
Gabryelewicz, A; Konturek, SJ; Kulesza, E1
Beauchamp, RD; Gomez, G; Greeley, GH; Nealon, WH; Thompson, JC; Townsend, CM1
Fanali, S; Farina, A; Nardi, A; Quaglia, MG1
Chayvialle, JA; Guillaume, P; Hahne, W; Loizeau, E; Miazza, BM; Turberg, Y1
Grendell, JH; Niederau, C; Rothman, SS1
Gardner, JD; Howard, JM; Jensen, RT; Jones, SW; Murphy, RB; Schneider, LH; Trampota, M1
Johnson, LR; Tabata, K; Yamaguchi, T1
Grendell, JH; Niederau, C; Niederau, M; Williams, JA1
Gardner, JD; Jensen, RT; Jones, SW; Murphy, RB; Rovati, LA; Setnikar, I; Zhou, ZC1
Iwamoto, Y; Kuzuya, T; Yamamoto, R1
Grendell, JH; Liddle, RA; Niederau, C; Williams, JA1
Ihse, I; Larsson, L; Lilja, I; Tarpila, E1
Dobronyi, I; Papp, M; Scarpignato, C; Varga, G1
Baba, S; Fujii, M; Fujisawa, T; Koide, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S3
Chang, JH; Moriyoshi, Y; Shimizu, K; Shiratori, K; Takeuchi, T; Watanabe, S1
Baba, S; Fujii, M; Fujisawa, T; Itoh, H; Nakamura, T; Okabayshi, Y; Otsuki, M; Tani, S1
Papp, M; Scarpignato, C; Varga, G1
Abe, M; Funakoshi, A; Shinozaki, H; Wakasugi, H1
Fang, XC1
Schusdziarra, V1
Csernansky, JG; Hicks, PB; Riney, SJ; Su, K; Vinogradov, S1
Adler, G; Beglinger, C; Dill, S; Meyer, B; Werth, B1
Baba, S; Inui, A; Sakatani, N1
Allescher, HD; Daniel, EE; Fox, JE; Kostolanska, F; Rovati, LA1
Dembinski, A; Jaworek, J; Konturek, PK; Konturek, SJ; Warzecha, Z1
Chisté, R; Giacovelli, G; Rovati, LC; Setnikar, I1
Fujii, K; Kishimoto, M; Miyoshi, A1
Arabatsis, P; Lehmann, KA; Schlüsener, M1
Adler, G; Arnold, R; Göke, B; Koop, I; Reinshagen, M; Rovati, LC; Schafmayer, A1
Ahrén, B; Karlsson, S1
Dionne, RA; Hargreaves, KM; Lavigne, GJ; Schmidt, EA1
Brailski, Kh; Dimitrov, B; Koparanova, A; Mendizova, A; Vladimirov, B1
Matsukura, S; Mitsukawa, T; Nakatsuru, K; Nishizono, F; Ohgo, S; Takemura, J1
Burt, S; Kerwin, JF; Kopecka, H; Lin, CW; Miller, T; Nadzan, AM; Witte, D1
de Jong, AJ; Douglas, BR; Jansen, JB; Lamers, CB; Rovati, LC; Woutersen, RA2
Brailski, Kh; Dimitrov, B; Koparandova, O; Mendizova, A; Vladimirov, B1
Crone, C; Eggstein, S; Farthmann, EH; Imdahl, A1
Bogdal, J; Konturek, JW; Konturek, SJ; Kurek, A; Oleksy, J; Rovati, L1
Bunney, BS; Chiodo, LA; Freeman, AS2
Gardiner, J; Grider, JR; Loewe, CJ; Vlahcevic, ZR1
Fukuoka, S; Fushiki, T; Iwai, K; Kondoh, M1
Ageel, AM; Parmar, NS; Tariq, M2
Smith, JP; Solomon, TE1
Vaccarino, AL; Vaccarino, FJ1
de Jong, AJ; Jansen, JB; Lamers, CB1
Ferrell, LD; Grendell, JH; Niederau, C1
Beauchamp, RD; Glass, EJ; Singh, P; Thompson, JC; Townsend, CM1
Ammon, HP; Goldfine, ID; Verspohl, EJ; Williams, JA; Wunderle, G1
Rezvani, A; Rhoads, DL; Stokes, KB; Way, EL1
Aitken, PG; Jaffe, DB; Nadler, JV1
Massei, R; Songa, V; Trazzi, R1
McCann, SM; Vijayan, E2
Goriacheva, TV; Ignatenko, LG; Karepova, ME; Vasilevskaia, LS1
Csernansky, JG; Glick, S; Mellentin, J1
Itoh, S; Katsuura, G1
Konturek, P; Konturek, SJ; Laskiewicz, J; Thor, P1
Jiang, LH; Kasser, RJ; Wang, RY1
Ammon, HP; Verspohl, EJ; Wunderle, G1
Ortalli, G; Pagnoni, B; Rovati, LC; Tiengo, M1
Funakoshi, A; Kitani, K; Miyasaka, K; Nakamura, R1
Tani, S1
Crawley, JN1
Ito, K; Iuchi, K; Nitta, M; Shimohara, K; Tsukamoto, G1
Baba, S; Inoue, T; Inui, A; Morioka, H; Oya, M; Sakatani, N2
Funakoshi, A; Ibayashi, H; Miyazaki, K; Nakano, I; Shinozaki, H1
Cieszkowski, M; Hladij, M; Konturek, SJ; Szewczyk, K; Tasler, J1
Iwasaki, A; Matsuo, Y1
Chisté, R; Makovec, F; Rovati, LC; Setnikar, I; Warrington, SJ1
Bani, M; Cereda, R; Chisté, R; Makovec, F; Pacini, MA; Revel, L; Setnikar, I2
Bani, M; Cereda, R; Chisté, R; Makovec, F; Pacini, MA; Revel, L; Rovati, LA; Rovati, LC; Setnikar, I2
Beglinger, C; Gyr, K; Hildebrand, P; Köhler, E; Setnikar, I1
Hansky, J; Smith, GC; Willis, GL1
Bani, M; Chistè, R; Makovec, F; Revel, L; Rovati, LC; Setnikar, I1
Kimura, I; Kimura, M; Kondoh, T1
Bani, M; Cereda, R; Chistè, R; Makovec, F; Pacini, MA; Revel, L; Rovati, LC1
Barthó, L; Holzer, P; Lembeck, F; Lippe, IT; Setnikar, I1
Beauchamp, RD; Le, S; Singh, P; Thompson, JC; Townsend, CM1
Kitani, K; Kurosawa, H; Miyasaka, K1
Kajiyama, G; Kishimoto, S; Kobayashi, H; Konemori, R; Kunita, T; Miyoshi, A; Okamoto, K; Shimizu, S; Takaba, N1
Hisamitsu, T; Okada, M1
Pfaus, JG; Phillips, AG1
Bareggi, SR; Bianchi, M; Mantegazza, P; Panerai, AE; Rovati, LC1
Eran, M; Faber, J; Freier, S1
Deupree, D; Hsiao, S1
Bunney, BS; Charney, DS; Glazer, WM; Heninger, GR; Innis, RB; Price, LH; Rubin, AL; Sternberg, DE1
Beauchamp, RD; Nealon, WH; Thompson, JC; Townsend, CM1
Davison, JS; Shillabeer, G3
Itoh, Z; Nakamura, T; Nakaya, M; Suzuki, T1
Kinscheck, IB; Mayer, DJ; Watkins, LR2
Miller, J; Price, C; Price, DD; Rafii, A; von der Gruen, A1
Schneider, LH1
Ambrose, FG; Autry, WL; Barbaz, BS; Gerber, R; Liebman, JM1
Baldy, WJ; Bean, AJ; Martin, GE1
Gardner, JD; Hahne, WF; Jensen, RT; Lemp, GF1
Bailey, A; Steigerwalt, RW; Williams, JA1
Akanuma, Y; Iwamoto, Y; Nakamura, R1
Asshauer, E; Rehner, M1
Baile, CA; McLaughlin, CL; Peikin, SR1
Bali, JP; Magous, R1
Guthrie, PD; Johnson, LR1
Ben-Horin, E; Ben-Horin, N; Frenk, H1
Chou, J; Costa, E; Iadarola, M; Tang, J; Yang, HY1
Caspari, J; Erckenbrecht, JF; Wienbeck, M1
Kaplita, PV; Roebuck, BD1
Caspary, WF; Lembcke, B; Lembcke, C1
Buéno, L; Fioramonti, J; Hondé, C1
Hsiao, S; Itoh, S; Katsuura, G1
Beglinger, C; Fried, M; Gyr, K; Koehler, E; Varga, L; Whitehouse, I1
Nakagawa, H; Nishimura, M; Park, JH; Urakawa, N1
Bunney, BS; Chiodo, LA1
Jansen, JB; Lamers, CB1
Belbeck, L; Collins, S; Forsyth, P; Walker, D1
Dellepiane, F; Michetti, P; Testa, R; Volpi, C1
Marunaka, T; Matsushima, E; Minami, Y; Umeno, Y1
Bignamini, AA; Casula, PL; Galeone, M; Moise, G1
Bergemann, W; Braun, HE; Consentius, K; Hirschmann, H; Marowski, B; Munck, A; Rehs, HU; Stopik, D; Wilke, G1
Di Frazzio, S; Mandalà, ML; Mazzone, O; Monello, S; Trovato, GM1
Blasi, A; Brogna, A; Catalano, F; Daniele, S; Mangiameli, A; Marletta, F; Scollo, L1
Aono, M; Moriga, M; Murakami, M; Uchino, H1
Iwaki, K; Kimura, K; Sanai, K; Umetsu, T1

Trials

21 trial(s) available for glutamine and proglumide

ArticleYear
[Stress ulcer and acute postoperative renal insufficiency. An attempt at preventive treatment with Solcoseryl and proglumide].
    Annales de l'anesthesiologie francaise, 1976, Volume: 17, Issue:5

    Topics: Actihaemyl; Acute Kidney Injury; Adult; Aged; Female; Glutamine; Humans; Male; Middle Aged; Peptic Ulcer; Postoperative Complications; Proglumide; Stress, Physiological; Tissue Extracts

1976
Double-blind clinical comparison between a gastrin-receptor antagonist, proglumide, and a histamine H2-blocker, cimetidine.
    Current medical research and opinion, 1978, Volume: 5, Issue:5

    Topics: Adult; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Female; Gastric Juice; Gastrins; Glutamine; Guanidines; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Proglumide; Stomach Ulcer; Time Factors

1978
[Controlled clinical evaluation of the therapeutic activity of 3 antiulcer agents in peptic ulcer: carbenoxolone, proglumide and zolimidine].
    La Clinica terapeutica, 1979, Mar-31, Volume: 88, Issue:6

    Topics: Aged; Carbenoxolone; Clinical Trials as Topic; Drug Evaluation; Female; Glutamine; Glycyrrhetinic Acid; Humans; Male; Middle Aged; Peptic Ulcer; Proglumide; Pyridines; Random Allocation

1979
Efficient treatment of gastric ulcer with proglumide (Milid) in outpatients (double blind trial).
    Acta hepato-gastroenterologica, 1979, Volume: 26, Issue:4

    Topics: Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Female; Glutamine; Humans; Male; Middle Aged; Proglumide; Prospective Studies; Stomach Ulcer

1979
[Effective out-patient treatment of gastric ulcer with proglumide: preliminary results (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1979, Mar-02, Volume: 104, Issue:9

    Topics: Adult; Aged; Ambulatory Care; Double-Blind Method; Duodenal Ulcer; Female; Gastric Acidity Determination; Gastrins; Gastroscopy; Glutamine; Humans; Male; Middle Aged; Placebos; Proglumide; Stomach Ulcer

1979
Double-blind comparison of the antirheumatic activity and gastric side-effects of indomethacin used alone or in combination with a gastro-protective agent, proglumide.
    Current medical research and opinion, 1976, Volume: 4, Issue:4

    Topics: Adult; Clinical Trials as Topic; Female; Glutamine; Humans; Indomethacin; Male; Middle Aged; Pepsinogens; Proglumide; Rheumatic Diseases

1976
Inhibition of gastric secretion by anti-gastrinic and H2-blocking agents.
    Scandinavian journal of gastroenterology. Supplement, 1976, Volume: 42

    Topics: Animals; Atropine; Benzamides; Clinical Trials as Topic; Depression, Chemical; Gastric Juice; Glutamine; Guinea Pigs; Histamine Antagonists; Humans; Metiamide; Pentagastrin; Peptic Ulcer; Proglumide; Rats; Secretory Rate; Tryptophan

1976
[Controlled study of the prevention of digestive hemorrhage caused by stress with proglumide].
    Medecine & chirurgie digestives, 1976, Volume: 5, Issue:8

    Topics: Clinical Trials as Topic; Drug Evaluation; Glutamine; Humans; Peptic Ulcer Hemorrhage; Proglumide; Stress, Physiological

1976
Oral administration of loxiglumide (CCK antagonist) inhibits postprandial gallbladder contraction without affecting gastric emptying.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:1

    Topics: Administration, Oral; Adult; Cholecystokinin; Double-Blind Method; Female; Food; Gallbladder; Gastric Emptying; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Random Allocation

1990
Lack of effect of the specific cholecystokinin receptor antagonist loxiglumide on cholecystokinin clearance from plasma in man.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:6

    Topics: Adult; Cholecystokinin; Female; Glutamine; Half-Life; Humans; Male; Proglumide

1990
A preliminary dose-ranging trial of proglumide for the treatment of refractory schizophrenics.
    Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:3

    Topics: Antipsychotic Agents; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Glutamine; Humans; Proglumide; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1989
Failure of proglumide, a cholecystokinin antagonist, to potentiate clinical morphine analgesia. A randomized double-blind postoperative study using patient-controlled analgesia (PCA).
    Anesthesia and analgesia, 1989, Volume: 68, Issue:1

    Topics: Adult; Cholecystokinin; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Glutamine; Humans; Male; Middle Aged; Morphine; Pain, Postoperative; Proglumide; Random Allocation; Self Administration

1989
Proglumide potentiates morphine analgesia for acute postsurgical pain.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:6

    Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Synergism; Female; Glutamine; Humans; Male; Molar, Third; Morphine; Pain Measurement; Pain, Postoperative; Proglumide

1989
[Treatment of peptic ulcer with milide (proglumide)].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:3

    Topics: Adult; Clinical Trials as Topic; Female; Glutamine; Humans; Male; Middle Aged; Peptic Ulcer; Proglumide; Wound Healing

1989
[Potentiation of opiates by administration of baclofen and proglumide during the intraoperative period].
    Minerva anestesiologica, 1988, Volume: 54, Issue:4

    Topics: Adult; Baclofen; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Female; Fentanyl; Glutamine; Humans; Intraoperative Period; Male; Middle Aged; Nitric Oxide; Proglumide; Random Allocation

1988
Does the cholecystokinin antagonist proglumide possess antipsychotic activity?
    Psychiatry research, 1986, Volume: 18, Issue:1

    Topics: Adult; Cholecystokinin; Female; Glutamine; Humans; Pilot Projects; Proglumide; Schizophrenia

1986
Pentagastrin induced motility pattern in the human upper gastrointestinal tract is reversed by proglumide.
    Gut, 1984, Volume: 25, Issue:9

    Topics: Duodenum; Gastrointestinal Motility; Glutamine; Humans; Jejunum; Male; Pentagastrin; Proglumide

1984
The effect of a gastrin-receptor antagonist on gastric acid secretion and serum gastrin in the Zollinger-Ellison syndrome.
    Journal of clinical gastroenterology, 1983, Volume: 5, Issue:1

    Topics: Adult; Cimetidine; Female; Gastric Acid; Gastrins; Glutamine; Humans; Male; Middle Aged; Proglumide; Zollinger-Ellison Syndrome

1983
[Controlled and double-blind study of the treatment of peptic ulcer with cimetidine and proglumide].
    La Clinica terapeutica, 1980, May-31, Volume: 93, Issue:4

    Topics: Adult; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Glutamine; Guanidines; Humans; Male; Middle Aged; Peptic Ulcer; Proglumide

1980
[Two-year study on incidence of ulcer recurrence following proglumide therapy. A comparative study].
    Die Medizinische Welt, 1981, Jan-30, Volume: 32, Issue:5

    Topics: Cimetidine; Duodenal Ulcer; Female; Follow-Up Studies; Glutamine; Humans; Male; Middle Aged; Proglumide; Recurrence

1981
[Duodenal ulcer - multicenter double-blind study with proglumide].
    Medizinische Klinik, 1981, Apr-10, Volume: 76, Issue:8

    Topics: Adult; Aged; Double-Blind Method; Duodenal Ulcer; Duodenoscopy; Female; Glutamine; Humans; Magnesium; Magnesium Silicates; Male; Middle Aged; Proglumide; Silicic Acid; Wound Healing

1981

Other Studies

145 other study(ies) available for glutamine and proglumide

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
[Several new inhibitors of gastric secretion].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1978, Volume: 64, Issue:6

    Topics: Animals; Benzodiazepinones; Depression, Chemical; Dogs; Gastric Juice; Gastric Mucosa; Glutamine; Glycopeptides; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Peptide Hydrolases; Piperazines; Proglumide

1978
[Occupational acne in carpentry workshops].
    Przeglad dermatologiczny, 1976, Issue:6 Suppl

    Topics: Acne Vulgaris; Glutamine; Humans; Male; Occupational Diseases; Proglumide

1976
[Proglumide in peptic ulcer and in gastroduodenal pathology. Clinical, biological and endoscopic study].
    Medecine & chirurgie digestives, 1979, Volume: 8, Issue:4

    Topics: Adult; Aged; Drug Evaluation; Duodenitis; Female; Gastritis; Gastrointestinal Diseases; Glutamine; Hernia, Hiatal; Humans; Male; Middle Aged; Peptic Ulcer; Proglumide

1979
Pharmacokinetic approach to proglumide long-term activity.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:4

    Topics: Animals; Female; Glutamine; Half-Life; Kinetics; Models, Biological; Proglumide; Rats; Time Factors

1979
[Therapeutic value of an antigastrin nonatropinic antisecretory drug in esogastroduodenal pathology].
    Medecine & chirurgie digestives, 1978, Volume: 7, Issue:5

    Topics: Adult; Aged; Esophagitis; Female; Gastrins; Gastrointestinal Diseases; Glutamine; Humans; Male; Middle Aged; Proglumide

1978
[Experimental study of the gastric inhibitory effect of proglumide in the rat (author's transl)].
    Gastroenterologie clinique et biologique, 1978, Volume: 2, Issue:12

    Topics: Animals; Depression, Chemical; Gastric Juice; Gastrins; Glutamine; Male; Proglumide; Rats; Secretory Rate

1978
[Action of proglumide on gastric acid secretion and motricity stimulated by pentagastrin in the non-anesthetized cat (author's transl)].
    Gastroenterologie clinique et biologique, 1977, Volume: 1, Issue:5

    Topics: Animals; Cats; Female; Gastric Mucosa; Gastrointestinal Motility; Glutamine; Male; Pentagastrin; Proglumide

1977
Differential effects of sulfated cholecystokinin octapeptide and proglumide injected intrathecally on antinociception induced by beta-endorphin and morphine administered intracerebroventricularly in mice.
    European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3

    Topics: Analgesics; Animals; beta-Endorphin; Glutamine; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Proglumide; Reaction Time; Sincalide

1990
Proglumide selectively potentiates supraspinal mu 1 opioid analgesia in mice.
    Neuropharmacology, 1990, Volume: 29, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glutamine; Male; Mice; Morphine; Morphine Dependence; Narcotics; Proglumide; Reaction Time; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu

1990
Proglumide analogues CR 1409 and CR 1392 inhibit cholecystokinin-stimulated insulin release more potently than exocrine secretion from the isolated perfused rat pancreas.
    Pancreas, 1990, Volume: 5, Issue:3

    Topics: Animals; Cholecystokinin; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Proglumide; Radioimmunoassay; Rats; Rats, Inbred Strains

1990
The effect of CR 1409, a potent CCK receptor antagonist, on basal and stimulated pancreatic secretion in rat.
    Pancreas, 1990, Volume: 5, Issue:1

    Topics: Animals; Bicarbonates; Dose-Response Relationship, Drug; Glutamine; Male; Pancreas; Pancreatic Juice; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Secretory Rate; Sincalide

1990
Comparison of the effect of lorglumide on pancreatic growth stimulated by camostate in rat and hamster.
    Life sciences, 1990, Volume: 46, Issue:4

    Topics: Animals; Cholecystokinin; Cricetinae; DNA; Esters; Gabexate; Gelatin; Glutamine; Guanidines; Male; Mesocricetus; Organ Size; Pancreas; Proglumide; Proteins; Rats; Rats, Inbred Strains; Stimulation, Chemical; Trypsin Inhibitors

1990
In vivo comparison of inhibition with proglumide and CR-1409 of cholecystokinin-induced pressure in the biliary tract of the guinea pig.
    Surgery, gynecology & obstetrics, 1990, Volume: 170, Issue:3

    Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Gallbladder; Glutamine; Guinea Pigs; Male; Muscle Contraction; Pressure; Proglumide; Time Factors; Transducers

1990
Effects of a cholecystokinin receptor antagonist on intestinal phase of pancreatic and biliary responses in man.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:3

    Topics: Adult; Bile Acids and Salts; Cholecystokinin; Food; Glutamine; Humans; Intestines; Male; Pancreas; Pancreatic Polypeptide; Proglumide; Receptors, Cholecystokinin

1990
Effect of loxiglumide on gallbladder contractile response to cerulein and food in humans.
    Gastroenterology, 1990, Volume: 98, Issue:5 Pt 1

    Topics: Adult; Ceruletide; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Feeding Behavior; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Reference Values; Time Factors

1990
Mechanism of inhibitory action of peptide YY on cholecystokinin-induced contractions of isolated dog ileum.
    Regulatory peptides, 1990, Feb-04, Volume: 27, Issue:2

    Topics: Animals; Cholecystokinin; Dogs; Female; Gallbladder; Glutamine; Ileum; Isometric Contraction; Male; Muscle Contraction; Peptide YY; Peptides; Proglumide; Sincalide

1990
Effect of a new cholecystokinin receptor antagonist loxiglumide on acute pancreatitis in two experimental animal models.
    Pancreas, 1990, Volume: 5, Issue:3

    Topics: Acute Disease; Animals; Ceruletide; Cholecystokinin; Disease Models, Animal; Glutamine; Male; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Taurocholic Acid

1990
Effect of loxiglumide (CR-1505) on bombesin- and meal-stimulated plasma cholecystokinin in man.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:4

    Topics: Adult; Bombesin; Cholecystokinin; Female; Food; Glutamine; Humans; Male; Proglumide; Receptors, Cholecystokinin

1990
Chronic administration of cholecystokinin antagonists reverses the enhancement of spinal morphine analgesia induced by acute pretreatment.
    Brain research, 1990, May-21, Volume: 516, Issue:2

    Topics: Analgesia; Animals; Cholecystokinin; Glutamine; Injections, Spinal; Male; Morphine; Proglumide; Rats; Rats, Inbred Strains; Spinal Cord

1990
[Effects of cholecystokinin, gastrin and proglumide on bile secretion in rats].
    Sheng li xue bao : [Acta physiologica Sinica], 1990, Volume: 42, Issue:2

    Topics: Animals; Bile; Cholecystokinin; Female; Glutamine; Male; Pentagastrin; Proglumide; Rats; Rats, Inbred Strains; Secretory Rate

1990
Lorglumide and loxiglumide inhibit gastrin-stimulated DNA synthesis in a rat tumoral acinar pancreatic cell line (AR42J).
    Cancer research, 1990, Sep-15, Volume: 50, Issue:18

    Topics: Animals; DNA, Neoplasm; Gastrins; Glutamine; Ornithine Decarboxylase; Pancreatic Neoplasms; Proglumide; Rats; Receptors, Cholecystokinin; Thymidine; Tumor Cells, Cultured

1990
Comparison of loxiglumide, a cholecystokinin receptor antagonist, and atropine on hormonal and meal-stimulated pancreatic secretion in man.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:7

    Topics: Adult; Atropine; Bicarbonates; Cholecystokinin; Duodenum; Eating; Food, Formulated; Glutamine; Humans; Infusions, Intravenous; Pancreas; Proglumide; Receptors, Cholecystokinin; Secretin; Secretory Rate

1990
Proglumide inhibits cholecystokinin and meal-stimulated pancreatic secretion and release of pancreatic polypeptide.
    Surgery, 1990, Volume: 108, Issue:3

    Topics: Amino Acids; Animals; Cholecystokinin; Dogs; Female; Gastrins; Glutamine; Male; Neurotensin; Oleic Acid; Oleic Acids; Pancreas; Pancreatic Polypeptide; Proglumide

1990
Determination of loxiglumide in pharmaceutical preparations by using capillary zone electrophoresis.
    Farmaco (Societa chimica italiana : 1989), 1990, Volume: 45, Issue:6 Suppl

    Topics: Electrophoresis; Glutamine; Proglumide; Tablets

1990
Mechanism of pancreatic growth induced by pancreatico-biliary diversion in the rat. Inhibition by proglumide, benzotript, and ranitidine.
    Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 112

    Topics: Adaptation, Physiological; Animals; Benzamides; Biliary Tract; Cholecystokinin; DNA; Gastrins; Glutamine; Male; Organ Size; Pancreas; Pancreatic Polypeptide; Proglumide; Proteins; Ranitidine; Rats; RNA; Secretin

1985
Effects of proglumide on ductal and basolateral secretion of pancreatic digestive enzymes.
    The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 1

    Topics: Amylases; Animals; Cholecystokinin; Chymotrypsinogen; Glutamine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Pancreas; Pancreatic Ducts; Proglumide; Proteins; Rabbits; Regression Analysis

1985
Proglumide analogues: potent cholecystokinin receptor antagonists.
    The American journal of physiology, 1985, Volume: 249, Issue:2 Pt 1

    Topics: Amylases; Animals; Glutamine; Guinea Pigs; In Vitro Techniques; Male; Mice; Pancreas; Proglumide; Rats; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship

1985
Effect of proglumide on rat pancreatic growth.
    The American journal of physiology, 1985, Volume: 249, Issue:2 Pt 1

    Topics: Animals; Cholecystokinin; DNA; Gastrins; Glutamine; Male; Organ Size; Pancreas; Proglumide; Proteins; Rats; Rats, Inbred Strains; RNA; Sincalide

1985
New proglumide-analogue CCK receptor antagonists: very potent and selective for peripheral tissues.
    The American journal of physiology, 1986, Volume: 250, Issue:6 Pt 1

    Topics: Amylases; Animals; Biological Assay; Cerebral Cortex; Cholecystokinin; Glutamine; Male; Mice; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide

1986
Structural features of various proglumide-related cholecystokinin receptor antagonists.
    The American journal of physiology, 1986, Volume: 251, Issue:6 Pt 1

    Topics: Amylases; Animals; Cholecystokinin; Glutamine; Guinea Pigs; Kinetics; Male; Mice; Pancreas; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship

1986
CR-1409: a potent inhibitor of cholecystokinin-stimulated amylase release and cholecystokinin binding in rat pancreatic acini.
    Pancreas, 1987, Volume: 2, Issue:1

    Topics: Amylases; Animals; Dose-Response Relationship, Drug; Glutamine; Male; N-Methylscopolamine; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Scopolamine Derivatives; Sincalide

1987
Pancreatic growth: interaction of exogenous cholecystokinin, a protease inhibitor, and a cholecystokinin receptor antagonist in mice.
    Gut, 1987, Volume: 28 Suppl

    Topics: Amylases; Animals; Cholecystokinin; Chymotrypsinogen; Esters; Gabexate; Glutamine; Guanidines; Male; Mice; Organ Size; Pancreas; Proglumide; Protease Inhibitors; Sincalide

1987
Proglumide treatment in bile-induced acute experimental pancreatitis.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1988, Volume: 3, Issue:2-3

    Topics: Acute Disease; Amylases; Animals; Bile; Glutamine; Male; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains

1988
Effect of a new potent CCK antagonist, lorglumide, on caerulein- and bombesin-induced pancreatic secretion and growth in the rat.
    British journal of pharmacology, 1989, Volume: 96, Issue:3

    Topics: Amylases; Anesthesia; Animals; Body Weight; Bombesin; Ceruletide; Cholecystokinin; DNA; Glutamine; In Vitro Techniques; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Trypsin

1989
Loxiglumide. A new proglumide analog with potent cholecystokinin antagonistic activity in the rat pancreas.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:6

    Topics: Amylases; Animals; Binding, Competitive; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; Pancreas; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide

1989
[Inhibitory effect of CR 1409 (cholecystokinin antagonist) on pancreatic exocrine secretion in rats].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1989, Volume: 86, Issue:1

    Topics: Amylases; Animals; Cholecystokinin; Glutamine; Male; Pancreas; Pancreatic Juice; Proglumide; Rats; Rats, Inbred Strains; Sincalide

1989
[Inhibitory effect of a new proglumide derivative, loxiglumide, on CCK action in isolated rat pancreatic acini].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1989, Volume: 86, Issue:1

    Topics: Amylases; Animals; Cholecystokinin; Glutamine; In Vitro Techniques; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Sincalide

1989
Effect of a new cholecystokinin receptor antagonist CR 1392 on caerulein-induced acute pancreatitis in rats.
    Pancreas, 1989, Volume: 4, Issue:2

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Glutamine; Humans; Male; Organ Size; Pancreas; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin

1989
Effects of a new proglumide analogue CR 1392 on pancreatic exocrine secretion in the rat.
    Digestion, 1989, Volume: 42, Issue:2

    Topics: Amylases; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide

1989
Pancreatic secretory and trophic response to caerulein in rats: effect of proglumide and lorglumide.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:3

    Topics: Amylases; Animals; Body Weight; Ceruletide; DNA; Glutamine; In Vitro Techniques; Organ Size; Pancreas; Pancreatic Juice; Proglumide; Proteins; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Trypsin

1989
The inhibitory effect of CR-1409 on amylase secretion and intracellular Ca2+ mobilization in rat pancreatic acini in vitro.
    The Japanese journal of physiology, 1989, Volume: 39, Issue:4

    Topics: Amylases; Animals; Benzofurans; Calcium; Carbachol; Ceruletide; Cytoplasm; Fluorescent Dyes; Fura-2; Gastrin-Releasing Peptide; Glutamine; In Vitro Techniques; Male; Pancreas; Peptides; Perfusion; Proglumide; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence

1989
[Effect of proglumide (PGM) on bile flow and contents in humans and animals].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1989, Volume: 11, Issue:4

    Topics: Adult; Aged; Animals; Bile; Cholagogues and Choleretics; Dogs; Female; Glutamine; Humans; Male; Middle Aged; Proglumide; Rats

1989
[Gastrointestinal hormones and cancers of the gastrointestinal tract].
    Zeitschrift fur Gastroenterologie, 1989, Volume: 27, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Colonic Neoplasms; DNA Replication; Gastrins; Glutamine; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Proglumide; Somatostatin; Tumor Cells, Cultured

1989
Treatment of biliary colic with loxiglumide.
    Lancet (London, England), 1989, Jul-15, Volume: 2, Issue:8655

    Topics: Biliary Tract Diseases; Cholecystokinin; Colic; Female; Glutamine; Humans; Male; Proglumide; Time Factors

1989
[The effect of cholecystokinin antagonists on satiety induced by cholecystokinin octapeptide in dogs].
    Nihon Naibunpi Gakkai zasshi, 1989, Oct-20, Volume: 65, Issue:10

    Topics: Animals; Blood-Brain Barrier; Cholecystokinin; Dogs; Eating; Glutamine; Injections, Intravenous; Injections, Intraventricular; Proglumide; Receptors, Cholecystokinin; Sincalide

1989
Effect of the novel cholecystokinin receptor antagonist CR-1392 on cholecystokinin-induced antroduodenal and pyloric motor activity in vivo.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3

    Topics: Animals; Cholecystokinin; Dogs; Duodenum; Electric Stimulation; Female; Gastrointestinal Motility; Glutamine; Male; Proglumide; Pyloric Antrum; Pylorus; Receptors, Cholecystokinin; Tetrodotoxin

1989
Cholecystokinin receptor antagonism by peptidergic and non-peptidergic agents in rat pancreas.
    The Journal of physiology, 1989, Volume: 411

    Topics: Animals; Benzodiazepinones; Bombesin; Ceruletide; Cholecystokinin; Devazepide; DNA; Esters; Gabexate; Glutamine; Guanidines; Pancreas; Pentagastrin; Proglumide; Protease Inhibitors; Proteins; Rats; Receptors, Cholecystokinin

1989
Pharmacokinetics and tolerance of repeated oral doses of loxiglumide.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:11

    Topics: Adult; Biotransformation; Cholecystokinin; Female; Glutamine; Humans; Male; Patient Compliance; Proglumide

1989
[Effect of CCK on the large intestine].
    Nihon Heikatsukin Gakkai zasshi, 1989, Volume: 25, Issue:5

    Topics: Animals; Cholecystokinin; Gastrointestinal Motility; Glutamine; Intestine, Large; Male; Muscle Contraction; Muscle, Smooth; Proglumide; Rats; Rats, Inbred Strains

1989
Differential effects of atropine and a cholecystokinin receptor antagonist on pancreatic secretion.
    Gastroenterology, 1989, Volume: 96, Issue:4

    Topics: Adult; Atropine; Cholecystokinin; Dose-Response Relationship, Drug; Esters; Feedback; Gabexate; Glutamine; Guanidines; Humans; Male; Pancreas; Peptide Hydrolases; Proglumide; Protease Inhibitors; Pulse; Reference Values

1989
Effects of three different cholecystokinin receptor antagonists on basal and stimulated insulin and glucagon secretion in mice.
    Acta physiologica Scandinavica, 1989, Volume: 135, Issue:3

    Topics: Animals; Benzodiazepinones; Blood Glucose; Devazepide; Female; Glucagon; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; Proglumide; Receptors, Cholecystokinin

1989
Effects of atropine, proglumide, and somatostatin analogue (SMS 201-995) on bombesin-induced gallbladder contraction and CCK secretion in humans.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:11

    Topics: Adult; Atropine; Bombesin; Cholecystokinin; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; Octreotide; Proglumide; Radioimmunoassay; Reference Values; Ultrasonography

1989
Hybrid cholecystokinin (CCK) antagonists: new implications in the design and modification of CCK antagonists.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Benzodiazepines; Benzodiazepinones; Chemical Phenomena; Chemistry; Cholecystokinin; Devazepide; Drug Design; Glutamine; Molecular Conformation; Proglumide; Receptors, Cholecystokinin; Stereoisomerism; Structure-Activity Relationship

1989
Modulation by CR-1409 (lorglumide), a cholecystokinin receptor antagonist, of trypsin inhibitor-enhanced growth of azaserine-induced putative preneoplastic lesions in rat pancreas.
    Cancer research, 1989, May-01, Volume: 49, Issue:9

    Topics: Animals; Azaserine; Cholecystokinin; Esters; Gabexate; Glutamine; Guanidines; Male; Pancreatic Neoplasms; Precancerous Conditions; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide; Trypsin Inhibitors

1989
[Treatment of peptic ulcer using proglumide (Milid)].
    Vutreshni bolesti, 1989, Volume: 28, Issue:1

    Topics: Adult; Chronic Disease; Drug Evaluation; Duodenal Ulcer; Female; Gastric Juice; Gastric Mucosa; Gastroscopy; Glutamine; Humans; Male; Middle Aged; Pentagastrin; Proglumide; Stomach Ulcer

1989
Growth of colorectal carcinoma cells: regulation in vitro by gastrin, pentagastrin and the gastrin-receptor antagonist proglumide.
    Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:4

    Topics: Animals; Carcinoembryonic Antigen; Carcinoma; Cell Division; Colorectal Neoplasms; Gastrins; Glutamine; Humans; Mice; Pentagastrin; Proglumide; Receptors, Cholecystokinin; Tumor Cells, Cultured

1989
CCK receptor antagonism by loxiglumide and gall bladder contractions in response to cholecystokinin, sham feeding and ordinary feeding in man.
    Gut, 1989, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Cholecystokinin; Food; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Receptors, Cholecystokinin; Sincalide

1989
[Effect of proglumide on choleresis in rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:2

    Topics: Animals; Bile; Cholagogues and Choleretics; Cholic Acids; Dehydrocholic Acid; Female; Glutamine; Male; Proglumide; Rats; Taurocholic Acid

1989
Further studies on the specificity of proglumide as a selective cholecystokinin antagonist in the central nervous system.
    Annals of the New York Academy of Sciences, 1985, Volume: 448

    Topics: Animals; Anorexia Nervosa; Antipsychotic Agents; Apomorphine; Brain; Cholecystokinin; Glutamine; Humans; Mesencephalon; Neurons; Proglumide; Receptors, Dopamine; Schizophrenia

1985
Selective inhibition of pentagastrin- and cholecystokinin-stimulated exocrine secretion by proglumide.
    Gastroenterology, 1985, Volume: 89, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cholecystokinin; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Glutamine; Histamine; Male; Pancreas; Pentagastrin; Proglumide; Rats; Secretin

1985
Influence of neural blockages and proglumide on rat pancreatic enzyme secretion in response to intraluminal fatty acid.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 186, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nerve Block; Cholecystokinin; Drug Interactions; Glutamine; Hexamethonium; Hexamethonium Compounds; Male; Oleic Acid; Oleic Acids; Pancreas; Pancreatic Juice; Parasympatholytics; Proglumide; Rats; Rats, Inbred Strains; Secretory Rate; Trypsin

1987
Proglumide, a cholecystokinin receptor antagonist, exacerbates alloxan-induced diabetes mellitus in Swiss mice.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:12

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glutamine; Insulin; Male; Mice; Proglumide; Time Factors

1987
Effects of gastrin, proglumide, and somatostatin on growth of human colon cancer.
    Gastroenterology, 1988, Volume: 95, Issue:6

    Topics: Adenocarcinoma; Animals; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Gastrins; Glutamine; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Proglumide; Somatostatin; Tumor Cells, Cultured

1988
Influence of cholecystokinin antagonist on the effects of cholecystokinin and bombesin on azaserine-induced lesions in rat pancreas.
    Gastroenterology, 1989, Volume: 96, Issue:2 Pt 1

    Topics: Animals; Azaserine; Bombesin; Cholecystokinin; Glutamine; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains

1989
Antagonism of cholecystokinin function in the rostral and caudal nucleus accumbens: differential effects on brain stimulation reward.
    Neuroscience letters, 1989, Feb-13, Volume: 97, Issue:1-2

    Topics: Animals; Brain; Cholecystokinin; Glutamine; Male; Nucleus Accumbens; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Reward; Septal Nuclei

1989
The cholecystokinin receptor antagonist CR1409 increases plasma cholecystokinin in rats.
    Regulatory peptides, 1989, Volume: 24, Issue:2

    Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; Male; Proglumide; Rats; Rats, Inbred Strains

1989
Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin.
    Gastroenterology, 1985, Volume: 88, Issue:5 Pt 1

    Topics: Acute Disease; Animals; Benzamides; Ceruletide; Dose-Response Relationship, Drug; Glutamine; Male; Mice; Necrosis; Pancreas; Pancreatitis; Proglumide; Receptors, Cell Surface; Receptors, Cholecystokinin; Secretin; Time Factors

1985
Proglumide, a gastrin receptor antagonist, inhibits growth of colon cancer and enhances survival in mice.
    Annals of surgery, 1985, Volume: 202, Issue:3

    Topics: Adenocarcinoma; Animals; Body Weight; Cell Division; Cell Line; Colon; Colonic Neoplasms; Gastric Fundus; Gastrins; Glutamine; Mice; Organ Size; Pancreas; Proglumide; Receptors, Cell Surface

1985
Proglumide (gastrin and cholecystokinin receptor antagonist) inhibits insulin secretion in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:3

    Topics: Animals; Cholecystokinin; Culture Techniques; Depression, Chemical; Female; Gastric Inhibitory Polypeptide; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Male; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide

1986
Proglumide exhibits delta opioid agonist properties.
    Alcohol and drug research, 1987, Volume: 7, Issue:3

    Topics: Animals; Binding, Competitive; Electric Stimulation; Enkephalin, Leucine; Enzyme Inhibitors; Glutamine; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Naloxone; Norepinephrine; Proglumide; Receptors, Opioid; Receptors, Opioid, delta; Synaptosomes

1987
Electrophysiological studies on the specificity of the cholecystokinin antagonist proglumide.
    Brain research, 1987, May-05, Volume: 410, Issue:2

    Topics: Action Potentials; Animals; Apomorphine; Brain; Cerebral Cortex; Cholecystokinin; Dopamine; Enkephalin, Methionine; gamma-Aminobutyric Acid; Glutamine; Male; Neurotensin; Proglumide; Rats; Receptors, Neurotransmitter; Sodium Glutamate; Substantia Nigra

1987
The effects of cholecystokinin and cholecystokinin antagonists on synaptic function in the CA1 region of the rat hippocampal slice.
    Brain research, 1987, Jul-07, Volume: 415, Issue:1

    Topics: Action Potentials; Animals; Benzamides; Female; Glutamine; Hippocampus; In Vitro Techniques; Proglumide; Rats; Rats, Inbred Strains; Sincalide; Sulfates; Synapses; Synaptic Transmission

1987
The effects of the cholecystokinin antagonist, proglumide, on gonadotropin release in the rat.
    Brain research bulletin, 1986, Volume: 16, Issue:4

    Topics: Animals; Castration; Cholecystokinin; Female; Follicle Stimulating Hormone; Glutamine; Gonadotropins, Pituitary; Injections, Intravenous; Injections, Intraventricular; Luteinizing Hormone; Male; Proglumide; Rats; Rats, Inbred Strains

1986
[Mechanism of the action of amino acids on gastric secretion].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:1

    Topics: Amino Acids; Animals; Dogs; Drug Interactions; Gastric Mucosa; Gastrins; Glutamine; Lysine; Proglumide; Secretin

1987
Differential effects of proglumide on mesolimbic and nigrostriatal dopamine function.
    Psychopharmacology, 1987, Volume: 91, Issue:4

    Topics: Animals; Apomorphine; Corpus Striatum; Dopamine; Glutamine; Haloperidol; Kainic Acid; Kinetics; Limbic System; Male; Proglumide; Rats; Receptors, Dopamine; Spiperone; Stereotyped Behavior; Substantia Nigra

1987
Potentiation of beta-endorphin effects by proglumide in rats.
    European journal of pharmacology, 1985, Jan-08, Volume: 107, Issue:3

    Topics: Analgesia; Animals; beta-Endorphin; Catalepsy; Dose-Response Relationship, Drug; Drug Synergism; Endorphins; Glutamine; Humans; Male; Proglumide; Rats; Rats, Inbred Strains; Sincalide

1985
The anti-CCK effect of glutaramic acid derivatives in anesthetized and conscious rats.
    Pancreas, 1988, Volume: 3, Issue:4

    Topics: Anesthesia; Animals; Cholecystokinin; Glutamine; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains

1988
Cholecystokinin in the regulation of intestinal motility and pancreatic secretion in dogs.
    The American journal of physiology, 1988, Volume: 255, Issue:4 Pt 1

    Topics: Animals; Benzodiazepinones; Bethanechol Compounds; Bicarbonates; Bombesin; Cholecystokinin; Devazepide; Dogs; Eating; Gastrins; Gastrointestinal Motility; Glutamine; Pancreatic Juice; Proglumide; Proteins; Reference Values

1988
Cholecystokinin antagonist lorglumide reverses chronic haloperidol-induced effects on dopamine neurons.
    Brain research, 1988, Nov-08, Volume: 473, Issue:1

    Topics: Action Potentials; Animals; Dopamine; Glutamine; Haloperidol; Male; Nucleus Accumbens; Proglumide; Rats; Rats, Inbred Strains; Septal Nuclei; Sincalide; Substantia Nigra

1988
Proglumide antagonizes cholecystokinin effects on plasma glucose and insulin in rats in vivo.
    European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2

    Topics: Animals; Blood Glucose; Cholecystokinin; Esters; Female; Gabexate; Glucose Tolerance Test; Glutamine; Guanidines; Insulin Antagonists; Male; Proglumide; Protease Inhibitors; Rats; Rats, Inbred Strains

1988
[Possible potentiation of morphine analgesia by proglumide].
    Minerva anestesiologica, 1988, Volume: 54, Issue:4

    Topics: Adolescent; Adult; Drug Synergism; Drug Therapy, Combination; Female; Glutamine; Humans; Middle Aged; Morphine; Pain, Postoperative; Proglumide

1988
Inhibitory effect of CR-1409, a competitive inhibitor of cholecystokinin, on pancreatic exocrine secretion in the conscious rat.
    The Tohoku journal of experimental medicine, 1988, Volume: 155, Issue:2

    Topics: Animals; Bicarbonates; Cholecystokinin; Dose-Response Relationship, Drug; Female; Glutamine; Male; Pancreatic Juice; Proglumide; Proteins; Rats; Rats, Inbred Strains; Reference Values; Sincalide

1988
Experimental acute pancreatitis induced by excessive doses of caerulein in rats; protective and therapeutic effects of trypsin inhibitor urinastatin and CCK receptor antagonist CR1392.
    The Kobe journal of medical sciences, 1988, Volume: 34, Issue:2

    Topics: Acute Disease; Animals; Ceruletide; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamine; Glycoproteins; Kinetics; Male; Microscopy, Electron; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Trypsin Inhibitors

1988
Attenuation of dark-induced hyperlocomotion by a cholecystokinin antagonist in the nucleus accumbens.
    Brain research, 1988, Nov-15, Volume: 473, Issue:2

    Topics: Animals; Cholecystokinin; Darkness; Exploratory Behavior; Glutamine; Light; Male; Motor Activity; Nucleus Accumbens; Proglumide; Rats; Rats, Inbred Strains; Reference Values; Septal Nuclei

1988
Synthesis and effect on gastric secretion of several di- or tripeptides related to proglumide.
    Chemical & pharmaceutical bulletin, 1988, Volume: 36, Issue:10

    Topics: Animals; Dipeptides; Gastric Acid; Glutamine; Male; Peptides; Proglumide; Rats; Rats, Inbred Strains

1988
Comparison of effects of proglumide and CR 1409, a new glutaramic acid derivative, on CCK-8-induced pancreatic polypeptide and insulin secretion in the dog.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1988, Volume: 20, Issue:1

    Topics: Animals; Cholecystokinin; Dogs; Glutamine; Insulin; Insulin Secretion; Pancreatic Polypeptide; Proglumide

1988
Effects of proglumide on pancreatic endocrine and exocrine function in healthy humans.
    Regulatory peptides, 1987, Volume: 17, Issue:6

    Topics: Adult; Food; Glutamine; Humans; Islets of Langerhans; Middle Aged; Pancreas; Pancreatic Function Tests; Pancreatic Polypeptide; Proglumide

1987
Effect of cholecystokinin receptor antagonist on pancreatic responses to exogenous gastrin and cholecystokinin and to meal stimuli.
    Gastroenterology, 1988, Volume: 94, Issue:4

    Topics: Animals; Cholecystokinin; Dogs; Food; Gastric Fistula; Gastrins; Glutamine; Pancreas; Pancreatic Fistula; Pancreatic Polypeptide; Proglumide; Receptors, Cholecystokinin

1988
[Recent developments in drugs antagonistic to factors causing peptic ulcer--clinical efficacy and problems; gastrin receptor blockaders].
    Nihon rinsho. Japanese journal of clinical medicine, 1988, Volume: 46, Issue:1

    Topics: Animals; Binding, Competitive; Cimetidine; Drug Therapy, Combination; Gastric Acid; Gastrins; Glutamine; Peptic Ulcer; Proglumide; Rats; Receptors, Gastrointestinal Hormone

1988
Pharmacokinetics of loxiglumide after single intravenous or oral doses in man.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:5

    Topics: Administration, Oral; Adult; Cholecystokinin; Chromatography, High Pressure Liquid; Glutamine; Humans; Infusions, Intravenous; Injections, Intravenous; Proglumide

1988
Anticholecystokinin activities of loxiglumide.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:10

    Topics: Anesthesia; Animals; Ceruletide; Cholecystokinin; Dogs; Female; Gallbladder; Gastrointestinal Motility; Glutamine; Guinea Pigs; In Vitro Techniques; Male; Mice; Pancreas; Proglumide; Rabbits; Rats; Rats, Inbred Strains; Species Specificity

1987
Loxiglumide protects against experimental pancreatitis.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:10

    Topics: Animals; Ceruletide; Diet; Female; Glutamine; Male; Mice; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Taurocholic Acid

1987
Pharmacological properties of lorglumide as a member of a new class of cholecystokinin antagonists.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:11

    Topics: Animals; Cholecystokinin; Dogs; Gallbladder; Glutamine; Guinea Pigs; Ileum; In Vitro Techniques; Mice; Muscle Contraction; Pancreas; Proglumide; Rats; Receptors, Cholecystokinin

1987
Biological effects of a proglumide derivative as cholecystokinin antagonist in conscious dogs.
    Regulatory peptides, 1987, Aug-17, Volume: 18, Issue:3-4

    Topics: Animals; Cholecystokinin; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Glutamine; Infusions, Intravenous; Pancreatic Juice; Pancreatic Polypeptide; Pentagastrin; Proglumide; Sincalide

1987
Central and peripheral proglumide administration and cholecystokinin-induced satiety.
    Regulatory peptides, 1986, Volume: 15, Issue:1

    Topics: Animals; Catheterization; Cerebral Ventricles; Cholecystokinin; Drinking Behavior; Feeding Behavior; Glutamine; Hypothalamus; Injections, Intraperitoneal; Male; Organ Specificity; Proglumide; Rats; Rats, Inbred Strains; Satiation; Stereotaxic Techniques

1986
Different peripheral and central antagonistic activity of new glutaramic acid derivatives on satiety induced by cholecystokinin in rats.
    Regulatory peptides, 1986, Dec-30, Volume: 16, Issue:3-4

    Topics: Animals; Dose-Response Relationship, Drug; Glutamine; Male; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Satiation; Sincalide

1986
Proglumide peptides and CCK antagonistic action in hog duodenal circular muscle.
    European journal of pharmacology, 1987, Feb-10, Volume: 134, Issue:2

    Topics: Animals; Cholecystokinin; Duodenum; Female; Glutamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Peptide Fragments; Proglumide; Receptors, Cholecystokinin; Structure-Activity Relationship; Swine

1987
Gastric and duodenal antiulcer and cytoprotective effects of proglumide in rats.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: Animals; Cell Survival; Cimetidine; Cysteamine; Duodenal Ulcer; Female; Gastric Acid; Gastric Mucosa; Glutamine; Indomethacin; Ligation; Male; Proglumide; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer

1987
Antispasmodic activity on the gallbladder of the mouse of CR 1409 (lorglumide) a potent antagonist of peripheral CCK.
    Pharmacological research communications, 1987, Volume: 19, Issue:1

    Topics: Animals; Atropine; Cholecystokinin; Dose-Response Relationship, Drug; Female; Gallbladder; Glutamine; Mice; Mice, Inbred Strains; Nifedipine; Papaverine; Parasympatholytics; Proglumide

1987
Evaluation of a new and potent cholecystokinin antagonist on motor responses of the guinea-pig intestine.
    British journal of pharmacology, 1987, Volume: 90, Issue:4

    Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Electric Stimulation; Female; Glutamine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Proglumide; Receptors, Cholecystokinin; Reflex

1987
Inhibition of pentagastrin-stimulated up-regulation of gastrin receptors and growth of mouse colon tumor in vivo by proglumide, a gastrin receptor antagonist.
    Cancer research, 1987, Oct-01, Volume: 47, Issue:19

    Topics: Animals; Colon; Colonic Neoplasms; Gastrins; Glutamine; Male; Mice; Pentagastrin; Proglumide; Receptors, Cholecystokinin

1987
Proglumide has access to brain and antagonizes the central satiety effect of cholecystokinin octapeptide in the dog.
    Brain research, 1987, Aug-11, Volume: 417, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain; Dogs; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Glutamine; Infusions, Intravenous; Injections, Intraventricular; Proglumide; Satiation; Satiety Response; Sincalide; Time Factors

1987
Proglumide stimulates basal pancreatic secretion in the conscious rat.
    Digestion, 1987, Volume: 37, Issue:3

    Topics: Animals; Bile; Consciousness; Feedback; Glutamine; Male; Pancreas; Pancreatic Juice; Proglumide; Rats; Rats, Inbred Strains

1987
Preventive effect of proglumide on erosive gastritis in the rat.
    Hiroshima journal of medical sciences, 1987, Volume: 36, Issue:2

    Topics: Animals; Gastric Mucosa; Gastrins; Gastritis; Glutamine; Male; Proglumide; Rats; Rats, Inbred Strains; Taurocholic Acid

1987
[Cholecystokinin antagonist (proglumide) potentiates the inhibitory effect of morphine on micturition reflex].
    Masui. The Japanese journal of anesthesiology, 1987, Volume: 36, Issue:6

    Topics: Animals; Cholecystokinin; Depression, Chemical; Drug Synergism; Female; Glutamine; Morphine; Proglumide; Rats; Rats, Inbred Strains; Reflex; Urination

1987
Pharmacological characterisation of a new potent and specific nonpolypeptidic cholecystokinin antagonist.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:6

    Topics: Animals; Cerebral Cortex; Cholecystokinin; Female; Gallbladder; Glutamine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Species Specificity

1987
Cholecystokinin facilitates ejaculation in male rats: blockade with proglumide and apomorphine.
    European journal of pharmacology, 1987, Sep-23, Volume: 141, Issue:3

    Topics: Animals; Apomorphine; Cholecystokinin; Copulation; Dose-Response Relationship, Drug; Ejaculation; Glutamine; Male; Proglumide; Rats; Sexual Behavior, Animal

1987
Effect of a cholecystokinin antagonist on some effects of diazepam.
    Neuropharmacology, 1987, Volume: 26, Issue:9

    Topics: Animals; Cholecystokinin; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Glutamine; Male; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Proglumide; Seizures

1987
Effect of cholecystokinin and of its antagonist, of atropine, and of food on the release of immunoglobulin A and immunoglobulin G specific antibodies in the rat intestine.
    Gastroenterology, 1987, Volume: 93, Issue:6

    Topics: Animals; Antibody Specificity; Atropine; Cholecystokinin; Food, Formulated; Glutamine; Immunoglobulin A; Immunoglobulin G; Intestinal Mucosa; Proglumide; Rats

1987
Cholecystokinin octapeptide, proglumide, and conditioned taste avoidance in rats.
    Physiology & behavior, 1987, Volume: 41, Issue:2

    Topics: Animals; Avoidance Learning; Conditioning, Psychological; Female; Glutamine; Proglumide; Rats; Sincalide; Sucrose; Taste

1987
Role of cholecystokinin in canine pancreatic exocrine response to bombesin stimulation.
    American journal of surgery, 1987, Volume: 153, Issue:1

    Topics: Animals; Bombesin; Cholecystokinin; Dogs; Drug Interactions; Glutamine; Infusions, Intravenous; Pancreas; Proglumide

1987
The effects of the cholecystokinin antagonist, proglumide, on prolactin secretion in the rat.
    Life sciences, 1987, Feb-16, Volume: 40, Issue:7

    Topics: Animals; Cholecystokinin; Female; Glutamine; Injections, Intravenous; Injections, Intraventricular; Male; Proglumide; Prolactin; Rats; Rats, Inbred Strains

1987
Proglumide, a cholecystokinin antagonist, increases gastric emptying in rats.
    The American journal of physiology, 1987, Volume: 252, Issue:2 Pt 2

    Topics: Administration, Oral; Animals; Cholecystokinin; Eating; Gastric Acid; Gastric Emptying; Glutamine; Injections, Intraperitoneal; Injections, Intravenous; Male; Mathematics; Proglumide; Rats; Rats, Inbred Strains; Time Factors

1987
[Effect of proglumide on gastrointestinal motility and gastric secretion in the conscious state].
    Nihon Heikatsukin Gakkai zasshi, 1985, Volume: 21, Issue:6

    Topics: Animals; Dogs; Gastric Acid; Gastrointestinal Motility; Glutamine; Muscle Contraction; Pentagastrin; Proglumide

1985
Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide.
    Brain research, 1985, Feb-18, Volume: 327, Issue:1-2

    Topics: Analgesia; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Drug Synergism; Glutamine; Injections, Spinal; Male; Microinjections; Morphine; Pain; Periaqueductal Gray; Proglumide; Rats; Rats, Inbred Strains; Reaction Time; Time Factors

1985
Potentiation of systemic morphine analgesia in humans by proglumide, a cholecystokinin antagonist.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:8

    Topics: Adult; Cholecystokinin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Glutamine; Humans; Injections, Intravenous; Morphine; Pain; Proglumide; Random Allocation

1985
The effect of vagotomy on the increase in food intake induced by the cholecystokinin antagonist, proglumide.
    Regulatory peptides, 1985, Volume: 12, Issue:2

    Topics: Animals; Appetite; Body Weight; Cholecystokinin; Energy Intake; Glutamine; Male; Proglumide; Rats; Rats, Inbred Strains; Vagotomy

1985
Cholecystokinin-8 and proglumide modulation of electrically elicited eating.
    Progress in clinical and biological research, 1985, Volume: 192

    Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Feeding Behavior; Glutamine; Hypothalamic Area, Lateral; Male; Proglumide; Rats; Rats, Inbred Strains; Sincalide

1985
Differential antagonism by proglumide of various CCK-mediated effects in mice.
    Progress in clinical and biological research, 1985, Volume: 192

    Topics: Animals; Body Temperature; Cerebral Ventricles; Glutamine; Injections, Intraventricular; Male; Mice; Motor Activity; Naloxone; Proglumide; Sincalide

1985
Chronic proglumide increases [3H]spiperone binding in the rat brain.
    European journal of pharmacology, 1985, Oct-29, Volume: 117, Issue:1

    Topics: Animals; Brain Chemistry; Butyrophenones; Cholecystokinin; Corpus Striatum; Glutamine; In Vitro Techniques; Kinetics; Male; Proglumide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone

1985
Proglumide and benzotript: members of a different class of cholecystokinin receptor antagonists.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:10

    Topics: Amylases; Animals; Benzamides; Carbachol; Cholecystokinin; Dibutyryl Cyclic GMP; Glutamine; Guinea Pigs; Kinetics; Male; Pancreas; Proglumide; Receptors, Cell Surface; Receptors, Cholecystokinin

1981
Effects of proglumide on pancreatic acinar cell function.
    Digestion, 1983, Volume: 27, Issue:4

    Topics: Amylases; Animals; Cholecystokinin; Deoxyglucose; Glutamine; Islets of Langerhans; Male; Mice; Proglumide; Receptor, Insulin; Receptors, Cell Surface; Receptors, Cholecystokinin

1983
In vitro and in vivo effect of proglumide on cholecystokinin-stimulated amylase release in mouse pancreatic acini.
    Gastroenterologia Japonica, 1984, Volume: 19, Issue:1

    Topics: Amylases; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Pancreas; Proglumide; Sincalide; Tetragastrin

1984
[Ulcer therapy with the gastrin receptor antagonist proglumide. Results of the field study].
    Die Medizinische Welt, 1981, May-15, Volume: 32, Issue:20

    Topics: Drug Tolerance; Duodenal Ulcer; Gastrins; Glutamine; Humans; Patient Compliance; Proglumide; Receptors, Cell Surface; Stomach Ulcer

1981
Feeding behavior response of Zucker rats to proglumide, a CCK receptor antagonist.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:6

    Topics: Animals; Feeding Behavior; Glutamine; Male; Proglumide; Rats; Rats, Zucker; Receptors, Cell Surface; Receptors, Cholecystokinin

1983
Evidence that proglumide and benzotript antagonize secretagogue stimulation of isolated gastric parietal cells.
    Regulatory peptides, 1983, Volume: 7, Issue:3

    Topics: Aminopyrine; Animals; Benzamides; Gastric Juice; Gastrins; Glutamine; In Vitro Techniques; Proglumide; Rabbits; Receptors, Cell Surface; Receptors, Cholecystokinin

1983
Proglumide inhibition of trophic action of pentagastrin.
    The American journal of physiology, 1984, Volume: 246, Issue:1 Pt 1

    Topics: Animals; DNA Replication; Drug Antagonism; Gastric Mucosa; Gastrins; Glutamine; Intestinal Mucosa; Kinetics; Male; Pancreas; Pentagastrin; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholecystokinin; Sebaceous Glands

1984
The effects of proglumide on morphine induced motility changes.
    Psychopharmacology, 1984, Volume: 84, Issue:4

    Topics: Animals; Glutamine; Male; Morphine; Motor Activity; Proglumide; Rats; Rats, Inbred Strains

1984
Proglumide prevents and curtails acute tolerance to morphine in rats.
    Neuropharmacology, 1984, Volume: 23, Issue:6

    Topics: Animals; Cholecystokinin; Drug Tolerance; Glutamine; Male; Morphine; Proglumide; Rats; Rats, Inbred Strains

1984
The cholecystokinin antagonist, proglumide, increases food intake in the rat.
    Regulatory peptides, 1984, Volume: 8, Issue:3

    Topics: Animals; Appetite; Cholecystokinin; Energy Intake; Fasting; Glutamine; Hunger; Male; Proglumide; Rats; Rats, Inbred Strains

1984
Proglumide antagonizes the stimulation of rabbit gallbladder by cholecystokinin.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 269, Issue:2

    Topics: Acetylcholine; Animals; Cholecystokinin; Female; Gallbladder; Glutamine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Proglumide; Rabbits; Serotonin

1984
Potentiation of opiate analgesia and apparent reversal of morphine tolerance by proglumide.
    Science (New York, N.Y.), 1984, Apr-27, Volume: 224, Issue:4647

    Topics: Analgesia; Animals; Brain; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Endorphins; Enkephalin, Methionine; Glutamine; Humans; Injections, Spinal; Morphine; Proglumide; Rats; Spinal Cord

1984
[Transmural gastric potential difference (PD) and intragastric diurnal pH profile with proglumide].
    Zeitschrift fur Gastroenterologie, 1983, Volume: 21, Issue:7

    Topics: Adult; Aspirin; Cimetidine; Circadian Rhythm; Double-Blind Method; Female; Gastric Acidity Determination; Gastric Mucosa; Glutamine; Humans; Male; Membrane Potentials; Proglumide

1983
Proglumide: selective antagonism of the rumination but not gastric motor effects induced by pentagastrin in sheep.
    Life sciences, 1984, Jan-30, Volume: 34, Issue:5

    Topics: Abomasum; Animals; Electromyography; Female; Gastroesophageal Reflux; Gastrointestinal Motility; Glutamine; Infusions, Parenteral; Injections, Intravenous; Injections, Intraventricular; Pentagastrin; Proglumide; Sheep; Stomach, Ruminant

1984
Cholecystokinin tetrapeptide, proglumide and open-field behavior in rats.
    Life sciences, 1984, May-28, Volume: 34, Issue:22

    Topics: Animals; Behavior, Animal; Defecation; Drug Synergism; Gastrins; Glutamine; Male; Motor Activity; Proglumide; Rats; Rats, Inbred Strains; Tetragastrin

1984
Effect of proglumide, a cholecystokinin receptor antagonist, on caerulein-stimulated pancreatic enzyme secretion and pancreatic polypeptide release in the dog.
    Regulatory peptides, 1984, Volume: 8, Issue:2

    Topics: Animals; Ceruletide; Cholecystokinin; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Glutamine; Pancreas; Pancreatic Juice; Pancreatic Polypeptide; Proglumide

1984
Effects of proglumide and metiamide on vagally stimulated gastric acid secretion in chickens.
    Nihon juigaku zasshi. The Japanese journal of veterinary science, 1982, Volume: 44, Issue:2

    Topics: Animals; Chickens; Gastric Acid; Glutamine; Male; Metiamide; Proglumide; Thiourea; Vagotomy; Vagus Nerve

1982
Proglumide: selective antagonism of excitatory effects of cholecystokinin in central nervous system.
    Science (New York, N.Y.), 1983, Mar-25, Volume: 219, Issue:4591

    Topics: Animals; Brain; Cerebral Cortex; Cholecystokinin; Drug Antagonism; Glutamine; Male; Mesencephalon; Neurons; Proglumide; Rats

1983
The effects of proglumide on cholecystokinin-, bombesin-, and glucagon-induced satiety in the rat.
    Life sciences, 1983, May-09, Volume: 32, Issue:19

    Topics: Animals; Appetite; Bombesin; Cholecystokinin; Dose-Response Relationship, Drug; Food Deprivation; Glucagon; Glutamine; Male; Peptides; Proglumide; Rats; Rats, Inbred Strains; Time Factors

1983
High-performance liquid chromatographic determination of proglumide in plasma.
    Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:8

    Topics: Chromatography, High Pressure Liquid; Glutamine; Humans; Male; Proglumide; Time Factors

1982
[Effects of proglumide on gastric motility].
    La Clinica terapeutica, 1981, Jan-15, Volume: 96, Issue:1

    Topics: Adult; Aged; Dyspepsia; Female; Gastric Emptying; Gastric Juice; Gastrointestinal Motility; Glutamine; Humans; Male; Middle Aged; Proglumide

1981
[Effect of acute administration of proglumide on serum gastrin and basal gastric acid secretion in normal subjects and patients with duodenal ulcer].
    La Clinica terapeutica, 1981, Apr-15, Volume: 97, Issue:1

    Topics: Adult; Duodenal Ulcer; Gastric Acid; Gastrins; Glutamine; Humans; Middle Aged; Proglumide

1981
The role of gastric mucosal hexosamine in aspirin-induced ulcers.
    Gastroenterologia Japonica, 1980, Volume: 15, Issue:1

    Topics: Animals; Aspirin; Gastric Mucosa; Glutamine; Hexosamines; Male; Proglumide; Rats; Stomach Ulcer; Wound Healing

1980
Effect of proglumide on glycoprotein synthesis in aspirin-induced gastric erosions in rats.
    European journal of pharmacology, 1980, May-30, Volume: 64, Issue:1

    Topics: Acetylglucosamine; Animals; Aspirin; Fasting; Gastric Mucosa; Glutamine; Glycoproteins; Male; Proglumide; Rats; Species Specificity; Stomach Ulcer

1980