glutamine has been researched along with nadp in 103 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (41.75) | 18.7374 |
| 1990's | 13 (12.62) | 18.2507 |
| 2000's | 15 (14.56) | 29.6817 |
| 2010's | 22 (21.36) | 24.3611 |
| 2020's | 10 (9.71) | 2.80 |
| Authors | Studies |
|---|---|
| Mäntsälä, P; Zalkin, H | 1 |
| Geary, LE; Meister, A | 1 |
| Schaeffer, F; Stanier, RY | 1 |
| Lea, PJ; Miflin, BJ | 1 |
| Coudert, M; Lemal, J; Vandecasteele, JP | 1 |
| Kotre, AM; Sakamoto, N; Savageau, MA | 1 |
| Curti, B; Edmondson, DE; Rescigno, M; Vanoni, MA; Zanetti, G | 1 |
| Curti, B; Nuzzi, L; Rescigno, M; Vanoni, MA; Zanetti, G | 1 |
| Chen, GJ; Russell, JB | 1 |
| Blachier, F; Malaisse, WJ; Sener, A | 1 |
| Kanamori, K; Roberts, JD; Weiss, RL | 1 |
| Eizirik, DL; Malaisse, WJ; Sandler, S; Sener, A | 1 |
| Capito, K; Hedeskov, CJ; Thams, P | 1 |
| Coulton, JW; Kapoor, M | 1 |
| van de Poll, KW | 1 |
| Brown, CM; Burn, VJ; Johnson, B | 1 |
| Dougall, DK | 1 |
| Folkes, BF; Sims, AP | 1 |
| Miller, RE | 1 |
| Fowler, MW; Jessup, W; Sarkissian, GS | 1 |
| Dubois, EL; Grenson, M | 1 |
| Al-Gharawi, A; Moore, D | 1 |
| Buniatian, GKh | 1 |
| Dennen, DW; Niederpruem, DJ | 1 |
| Chamalaun, RA; Tager, JM | 1 |
| Folkes, BF | 1 |
| Kajinami, S; Smith, EC | 1 |
| Johnstone, RM; Trachewsky, D | 1 |
| Langer, BW; Smith, WJ; Theodorides, VJ | 1 |
| Bart, C; Hudock, GA | 1 |
| Kovacević, Z; Morris, HP | 1 |
| Kovacević, Z | 1 |
| Elmerich, C | 1 |
| Araújo, EF; Caldas, RA; Felix, CR; Roitman, I | 1 |
| Lehninger, AL; Moreadith, RW | 1 |
| Nicklas, WJ | 1 |
| Dufrane, SP; Malaisse, WJ; Malaisse-Lagae, F; Sener, A | 1 |
| Hummelt, G; Mora, J | 1 |
| Christophe, J; Hutton, JC; Malaisse, WJ; Malaisse-Legae, F; Sener, A | 1 |
| Garcia-Morales, P; Malaisse, WJ; Malaisse-Lagae, F; Sener, A; Valverde, I | 1 |
| Malaisse, WJ; Malaisse-Lagae, F; Sener, A | 1 |
| Bier, DM; Hellerström, C; Malaisse, WJ; Malaisse-Lagae, F; Matthews, DE; Sener, A; Welsh, M | 1 |
| Costa Rosa, LF; Curi, R; Murphy, C; Newsholme, P | 1 |
| Carper, DA; Hohman, TC; Old, SE | 1 |
| Nordlund, S; Norén, A | 1 |
| Accornero, P; Carrera, G; Curti, B; Vanoni, MA | 1 |
| Friedman, S; Gao, JP; Lanks, KW | 1 |
| Cabacungan, EB; Fox, RE; Hopkins, IB; Tildon, JT | 1 |
| Fontecilla-Camps, JC; Frey, M; Gomez-Moreno, C; Medina, M; Serre, L; Vellieux, F | 1 |
| Murphy, C; Newsholme, P | 1 |
| Sligar, SG; Yeom, H | 1 |
| Bradrick, TD; Howell, EE; Park, H | 1 |
| Dodzin, ME; Vinogradova, KA | 1 |
| MacLeish, PR; Poitry, S; Poitry-Yamate, C; Tsacopoulos, M; Ueberfeld, J | 1 |
| Daff, S; Sagami, I; Sato, Y; Shimizu, T | 1 |
| Adams, MJ; Ciccone, T; Cosgrove, MS; Davino, MH; Fairbairn, L; Levy, HR; Lin, Y; Vought, V | 1 |
| Haynes, TE; Li, H; Meininger, CJ; Wu, G; Yan, W | 1 |
| Colman, RF; Huang, YC | 1 |
| Curti, B; Dossena, L; Florencio, FJ; Martin-Figueroa, E; Mattevi, A; Morandi, P; Ravasio, S; Vanoni, MA | 1 |
| Howell, EE; Saxton, AM; Smiley, RD; Stinnett, LG | 1 |
| Cotton, NP; Jackson, JB; Quirk, PG; van Boxel, GI; White, SA | 1 |
| HOLZER, H; SCHNEIDER, S | 1 |
| POMEROY, LR; ROACH, MK; SIEGEL, FL | 1 |
| DEMOSS, JA | 1 |
| Birch, DJ; Evans, ND; Gnudi, L; Pickup, JC; Rolinski, OJ | 1 |
| Bergamini, CM; Cervellati, C; Cook, PF; Dallocchio, F | 1 |
| Finazzi, G; Hippler, M; Sommer, F | 1 |
| Chang, GG; Hsieh, JY; Hung, HC; Liu, GY | 1 |
| Bartnik, BL; Hovda, DA; Lee, SM; Sutton, RL | 1 |
| Ames, B; Bland, DA; Hagar, W; Klings, ES; Kuypers, FA; Larkin, S; Morris, CR; Shigenaga, M; Steinberg, MH; Suh, JH; Vichinsky, EP | 1 |
| Chandel, NS; Weinberg, F | 1 |
| Becker, TC; Ilkayeva, O; Jensen, MV; Joseph, JW; Lu, D; Newgard, CB; Odegaard, ML; Ronnebaum, SM | 1 |
| Thompson, CB; Wise, DR | 1 |
| Levine, AJ; Puzio-Kuter, AM | 1 |
| Barkhouse, DA; Castegna, A; Curtis, MT; Fabis-Pedrini, MJ; Hooper, DC; Kean, RB; Palmieri, F; Palmieri, L; Porcelli, V; Spera, I | 1 |
| Chandel, NS; Chen, PH; Cheng, T; DeBerardinis, RJ; Jin, ES; Linehan, WM; Mullen, AR; Sullivan, LB; Wheaton, WW; Yang, Y | 1 |
| Di Nardo, G; Gilardi, G; Goyal, A; Sideri, A; Tsotsou, GE | 1 |
| Galeffi, F; Turner, DA | 1 |
| Du, W; Jiang, P; Mancuso, A; Wellen, KE; Yang, X | 1 |
| Cantley, LC; Kimmelman, AC; Lyssiotis, CA; Son, J | 1 |
| Asara, JM; Cantley, LC; Lyssiotis, CA; Paik, JH; Yeo, H; Ying, H; Zhang, Y | 1 |
| Cipolleschi, MG; D'Amico, M; Dello Sbarba, P; Fredducci, D; Marzi, I; Olivotto, M; Rovida, E; Santini, R; Stecca, B; Stivarou, T; Torre, E; Vinci, MC | 1 |
| Alberghina, L; Gaglio, D | 1 |
| Chakrabarti, G | 1 |
| Dinamarca, J; Falkowski, PG; Gorbunov, MY; Levitan, O; Zelzion, E | 1 |
| Blair, IA; Glickson, JD; Guo, L; Leeper, DB; Nath, K; Nelson, DS; Shestov, AA; Worth, AJ | 1 |
| Kim, BM; Kim, YJ; Lee, G; Lee, KH; Lee, YM; Lim, BO; Lim, JH; Oh, TI; Shim, DW | 1 |
| Adams, ND; DeBerardinis, RJ; Dranka, BP; Jiang, L; McCabe, MT; Metallo, CM; Parker, SJ; Pietrak, B; Schmidt, S; Schwartz, B; Shestov, AA; Swain, P; Terada, LS; Wang, QA; Yang, C | 1 |
| Cavallini, L; Chiarugi, P; Giannoni, E; Ippolito, L; Marini, A; Morandi, A; Pietrovito, L; Pintus, G; Puhr, M; Schrader, T; Taddei, ML | 1 |
| Cheng, JK; Gao, X; Huang, X; Lei, QY; Liu, YB; Wang, J; Wang, TS; Wang, YP; Xu, YY; Zhou, W; Zou, SW; Zuo, Y | 1 |
| Andreo, CS; Drincovich, MF; Martinatto, A; Moreno, S; Tronconi, MA; Valacco, MP; Zubimendi, JP | 1 |
| Baldi, R; Chang, CY; Liu, J; Liu, W; Liu, X; Locasale, JW; McDonnell, DP; Park, S; Safi, R | 1 |
| Alam, MT; Correia-Melo, C; Haas, R; Herrera-Dominguez, L; Kamrad, S; Méndez-Lucio, O; Miller-Fleming, L; Mülleder, M; Olin-Sandoval, V; Peña Navarro, DA; Ralser, M; Segal, J; Vowinckel, J; Yu, JSL | 1 |
| Almeida, MM; Curi, R; Domenech, P; Gorjão, R; Gritte, RB; Levada-Pires, AC; Newsholme, P; Pithon-Curi, TC; Poma, SO; Silva, EBD; Souza-Siqueira, T; Zambonatto, RF | 1 |
| Chang, HW; Han, MW; Kim, MR; Kim, SH; Kim, SW; Kim, SY; Lee, JC; Lee, M; Lee, YS; Nam, HY; Park, JJ | 1 |
| Lien, EC; Vander Heiden, MG | 1 |
| Fang, J; Guo, D; Jiang, Y; Li, L; Li, M; Liang, J; Lin, SH; Lu, Z; Ma, C; Shao, F; Tong, Y; Yang, D; Yu, Q; Yu, R | 1 |
| Cai, L; Hu, X; Ying, M; You, D; Zeng, S; Zhu, X | 1 |
| Clasquin, MF; Rabinowitz, JD; TeSlaa, T; Tesz, GJ; Xing, G; Xu, X; Yang, L; Zeng, X; Zhang, Z | 1 |
| Aurora, AB; Bezwada, D; DeBerardinis, RJ; Gill, JG; Gu, W; Kasitinon, SY; Khivansara, V; Leach, A; Martin-Sandoval, M; Mathews, TP; Morrison, SJ; Tasdogan, A; Yang, C; Zhao, Z | 1 |
| Cui, X; Huang, S; Jiang, C; Li, W; Lin, R; Liu, K; Liu, Y; Ma, J; Miao, H; Qiu, S; Wang, Z; Wu, W; Zhang, Y; Zou, L | 1 |
| Fan, S; Huang, Q; Peng, X; Su, S; Wei, Y; Wu, D; Xia, L; Yang, G; Yang, Y; Zha, X | 1 |
| Chen, S; He, P; Hu, S; Wang, X; Zhang, Y; Zhao, C | 1 |
9 review(s) available for glutamine and nadp
| Article | Year |
|---|---|
[Mechanisms of ammonia formation in the brain].
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Oxidoreductases; Amino Acids; Ammonia; Animals; Aspartic Acid; Brain; Brain Chemistry; Deamination; Dogs; Flavin-Adenine Dinucleotide; Fumarates; Glutamate Dehydrogenase; Glutaminase; Glutamine; Guanosine Triphosphate; Inosine Nucleotides; Mitochondria; Monoamine Oxidase; NAD; NADP; Nerve Tissue Proteins; Niacinamide; Oxidation-Reduction; Oxygen Consumption; Rats | 1973 |
Amino acid metabolism in the central nervous system: role of glutamate dehydrogenase.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Central Nervous System; Cerebellar Ataxia; Enzyme Activation; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Glutamate Synthase; Glutamates; Glutamic Acid; Glutamine; Humans; Leucine; Mitochondria; NADP; Nerve Endings; Neuroglia; Rats; Syndrome | 1984 |
[Streptomyces L-glutamate oxidase: use in clinical and fundamental medicine].
Topics: Amino Acid Oxidoreductases; Ammonia; Animals; Aspartate Aminotransferases; Biosensing Techniques; Central Nervous System; Creatinine; Glutamic Acid; Glutamine; Humans; Magnesium; Mammals; NAD; NADP; Streptomyces; Urea | 1999 |
Mitochondrial metabolism and cancer.
Topics: Adenosine Triphosphate; Animals; Citric Acid Cycle; Glutamine; Glycolysis; Humans; Mitochondria; Models, Biological; NADP; Neoplasms; Reactive Oxygen Species | 2009 |
Glutamine addiction: a new therapeutic target in cancer.
Topics: Animals; Glutamine; Humans; Mitochondria; Molecular Targeted Therapy; NADP; Neoplasms; Nucleotides; Protein Biosynthesis; TOR Serine-Threonine Kinases | 2010 |
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes.
Topics: Adenosine Triphosphate; Cell Division; Citric Acid Cycle; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glucose; Glutamine; Glycolysis; Humans; NADP; Neoplasms; Oncogenes; Pentose Phosphate Pathway; Signal Transduction | 2010 |
Exploiting metabolic differences in glioma therapy.
Topics: Brain Neoplasms; Glioma; Glutamic Acid; Glutamine; Humans; Hypoxia-Inducible Factor 1; NAD; NADP; Signal Transduction | 2012 |
Redox control of glutamine utilization in cancer.
Topics: Amino Acids; Antineoplastic Agents; Glutamine; Glycolysis; Humans; Lipids; Mitochondria; Mitochondrial Proteins; NAD; NADP; NADP Transhydrogenase, AB-Specific; Neoplasms; Oxidation-Reduction; Pentose Phosphate Pathway; Reactive Oxygen Species | 2014 |
The Critical Role of Cell Metabolism for Essential Neutrophil Functions.
Topics: Animals; Cell Hypoxia; Cytokines; Fatty Acids; Glucose; Glutamine; Hormones; Humans; Mitochondria; NADP; NADPH Oxidases; Neutrophils; Physical Conditioning, Animal; Reactive Oxygen Species; Superoxides | 2020 |
94 other study(ies) available for glutamine and nadp
| Article | Year |
|---|---|
Glutamate synthase. Properties of the glutamine-dependent activity.
Topics: Binding Sites; Escherichia coli; Glutamate Synthase; Glutamine; Immunodiffusion; Iodoacetamide; Ketones; Kinetics; NADP; Protein Binding; Transaminases | 1976 |
On the mechanism of glutamine-dependent reductive amination of alpha-ketoglutarate catalyzed by glutamate synthase.
Topics: Ammonia; Apoenzymes; Dithionite; Enterobacter; Enterobacteriaceae; Escherichia coli; Flavins; Glutamate Synthase; Glutamates; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Iron; Ketoglutaric Acids; NADP; Transaminases; Water | 1977 |
Glucose-6-phosphate dehydrogenase of Anabaena sp. Kinetic and molecular properties.
Topics: Adenosine Triphosphate; Cyanobacteria; Glucosephosphate Dehydrogenase; Glucosephosphates; Glutamine; Kinetics; Molecular Weight; NADP; Ribulosephosphates | 1978 |
Glutamate synthase in blue-green algae.
Topics: Ammonia; Cyanobacteria; Dithionite; Ferredoxins; Glutamate Synthase; Glutamates; Glutamine; Ketoglutaric Acids; NAD; NADP; Nitrogen; Transaminases | 1975 |
Pathways and regulation of glutamate synthesis in a Corynebacterium sp. overproducing glutamate.
Topics: Ammonium Sulfate; Cell-Free System; Corynebacterium; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Ketoglutaric Acids; Lysine; NAD; NADP; Nitrates; Soil Microbiology | 1975 |
Glutamate dehydrogenase from Escherichia coli: purification and properties.
Topics: Ammonia; Ammonium Sulfate; Cell-Free System; Chemical Precipitation; Chromatography, Gel; Escherichia coli; Glutamate Dehydrogenase; Glutamate Synthase; Glutamates; Glutamine; Hot Temperature; Ketoglutaric Acids; Kinetics; Molecular Weight; NADP; Peptides | 1975 |
Mechanistic studies on Azospirillum brasilense glutamate synthase.
Topics: Ammonia; Azospirillum brasilense; Glutamate Synthase; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; NADP; Oxidation-Reduction; Pyridines | 1991 |
The kinetic mechanism of the reactions catalyzed by the glutamate synthase from Azospirillum brasilense.
Topics: Ammonia; Azospirillum brasilense; Glutamate Synthase; Glutamine; Ketoglutaric Acids; Kinetics; NADP; Oxidation-Reduction; Spectrophotometry; Substrate Specificity; Tritium | 1991 |
Transport of glutamine by Streptococcus bovis and conversion of glutamine to pyroglutamic acid and ammonia.
Topics: Ammonia; Biological Transport, Active; Glutamates; Glutamine; Ketoglutaric Acids; NADP; Pyrrolidonecarboxylic Acid; Streptococcus | 1989 |
Crabtree effect in tumoral pancreatic islet cells.
Topics: Adenine Nucleotides; Adenoma, Islet Cell; Animals; Glucose; Glutamine; Lactates; Lactic Acid; Lipids; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Pancreatic Neoplasms; Tumor Cells, Cultured | 1988 |
Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies.
Topics: Alanine; Alanine Dehydrogenase; Alanine Transaminase; Amino Acid Oxidoreductases; Ammonia; Bacillus; Glutamate Dehydrogenase; Glutamate Synthase; Glutamates; Glutamic Acid; Glutamine; Magnetic Resonance Spectroscopy; NADP; Nitrates; Nitrogen Fixation | 1987 |
Defective catabolism of D-glucose and L-glutamine in mouse pancreatic islets maintained in culture after streptozotocin exposure.
Topics: Animals; Aspartate Aminotransferases; Cells, Cultured; Cytosol; Diabetes Mellitus, Experimental; Glucokinase; Glucose; Glutamate Dehydrogenase; Glutamine; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexokinase; Islets of Langerhans; Male; Mice; Mitochondria; NAD; NADP; Streptozocin | 1988 |
Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion.
Topics: Animals; Carboxylic Acids; Cytosol; Fructose; Glucose; Glutamine; Insulin; Islets of Langerhans; Leucine; Male; Mice; NAD; NADP | 1987 |
Studies on the kinetics and regulation of glutamate dehydrogenase of Salmonella typhimurium.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amination; Ammonia; Deamination; Electrophoresis, Polyacrylamide Gel; Glutamate Dehydrogenase; Glutamates; Glutamine; Ketoglutaric Acids; Kinetics; Malates; NADP; Salmonella typhimurium; Stereoisomerism | 1973 |
Ammonium repression in a mutant of Saccharomyces carlsbergensis lacking NADP dependent glutamate dehydrogenase activity.
Topics: Allantoin; Amidohydrolases; Ammonium Sulfate; Asparagine; Diploidy; Genes, Regulator; Genotype; Glutamate Dehydrogenase; Glutamine; Mutation; NADP; Saccharomyces | 1973 |
Presence of glutamate synthase in fission yeasts and its possible role in ammonia assimilation.
Topics: Ammonia; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Ketoglutaric Acids; NAD; NADP; Saccharomyces; Transaminases | 1973 |
Evidence for the presence of glutamate synthase in extracts of carrot cell cultures.
Topics: Ammonium Chloride; Asparagine; Cells, Cultured; Chromatography, Gel; Dialysis; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Kinetics; NAD; NADP; Nitrates; Oxidation-Reduction; Plants; Spectrophotometry, Ultraviolet; Transaminases | 1974 |
The significance of amino acid inhibition of NADP-linked glutamate dehydrogenase in the physiological control of glutamate synthesis in Candida utilis.
Topics: Amino Acids; Ammonia; Candida; Cell Count; Cell Division; Culture Media; DNA Replication; Feedback; Fungal Proteins; Glutamate Dehydrogenase; Glutamates; Glutamine; Isotope Labeling; Kinetics; NADP; Nitrogen; Nitrogen Isotopes; RNA; Temperature | 1974 |
Glutamate synthase from Escherichia coli--an iron-sulfur flavoprotein. Separation and analysis of non-identical subunits.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Chromatography, Gel; Chromatography, Thin Layer; Dansyl Compounds; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamine; Ketoglutaric Acids; Macromolecular Substances; Molecular Weight; NADP; Protein Binding; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Transaminases | 1974 |
Glutamate synthetase type activity in higher plants.
Topics: Asparagine; Cells, Cultured; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Isoenzymes; Ketoglutaric Acids; Kinetics; NAD; NADP; Oxaloacetates; Oxidation-Reduction; Plants; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors; Transaminases | 1974 |
Absence of involvement of glutamine synthetase and of NAD-linked glutamate dehydrogenase in the nitrogen catabolite repression of arginase and other enzymes in Saccharomyces cerevisiae.
Topics: Allantoin; Alleles; Amidohydrolases; Ammonia; Arginase; Enzyme Repression; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Mutation; NAD; NADP; Nitrogen; Saccharomyces cerevisiae; Species Specificity | 1974 |
Effects of D-glutamate on mycelial growth and glutamate dehydrogenase enzymes of Coprinus lagopus.
Topics: Acetates; Basidiomycota; Cell-Free System; Glucose; Glutamate Dehydrogenase; Glutamates; Glutamine; Isoenzymes; Ketoglutaric Acids; Kinetics; NAD; NADP; Quaternary Ammonium Compounds; Spectrophotometry; Stereoisomerism; Urea | 1974 |
Regulation of glutamate dehydrogenases during morphogenesis of Schizophyllum commune.
Topics: Ammonia; Basidiomycota; Cell Differentiation; Glutamate Dehydrogenase; Glutamine; Guanine Nucleotides; NAD; NADP; Spores | 1967 |
Nitrogen metabolism in the perfused rat liver.
Topics: Alanine; Ammonia; Ammonium Chloride; Animals; Aspartic Acid; Glutamate Dehydrogenase; Glutamates; Glutamine; Hydroxybutyrate Dehydrogenase; Liver; NAD; NADP; Nitrogen; Perfusion; Rats; Stimulation, Chemical; Urea | 1970 |
The physiology of the synthesis of amino acids and their movement into the seed proteins of plants.
Topics: Amino Acids; Asparagine; Carbon Isotopes; Edible Grain; Glutamine; NADP; Nitrogen; Photosynthesis; Plant Proteins; Seeds | 1970 |
Glutamine synthetase from Nocardia corallina.
Topics: Amino Acids; Carbamates; Feedback; Glucosamine; Glutamine; Ligases; NAD; NADP; Nocardia; Nucleotides | 1971 |
Utilization of ammonium ions for purine precursor synthesis in soluble extracts of Ehrlich ascites cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell Line; Cell-Free System; Deoxyribonucleotides; Diazooxonorleucine; Formates; Glucose; Glutamine; Glycine; Hydrogen-Ion Concentration; Mice; NADP; Neoplasms, Experimental; Nucleic Acids; Nucleotides; Protein Biosynthesis; Purines; Pyrimidines; Quaternary Ammonium Compounds; Ribonucleotides; Serine; Sodium | 1969 |
Conversion of the alpha-hydroxy and alpha-keto analogues of methionine to methionine by cell-free extracts of adult female Ascaris suum.
Topics: Ascaris; Asparagine; Aspartic Acid; Butyrates; Cell-Free System; Female; Glutamates; Glutamine; Methionine; NAD; NADP; Oxidation-Reduction; Proteins | 1971 |
Synthesis of NADP-dependent triosephosphate dehydrogenase independent of illumination in Chlorella variegata.
Topics: Amino Acids; Ammonium Chloride; Chlorella; Chlorophyll; Chlorophyta; Chloroplasts; Culture Media; Darkness; Glutamine; Glyceraldehyde-3-Phosphate Dehydrogenases; Light; NADP; Photochemistry; Radiation Effects; Urea | 1972 |
The role of glutamine in the oxidative metabolism of malignant cells.
Topics: Ammonia; Animals; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cyanides; Glutamates; Glutaminase; Glutamine; Hydrazones; In Vitro Techniques; Ketoglutaric Acids; Kinetics; Liver Neoplasms; Mice; Mitochondria; NADP; Neoplasms, Experimental; Oxygen Consumption; Pyruvates; Rats; Rotenone | 1972 |
The pathway of glutamine and glutamate oxidation in isolated mitochondria from mammalian cells.
Topics: Acetates; Animals; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamate Dehydrogenase; Glutamates; Glutaminase; Glutamine; In Vitro Techniques; Kidney; Mice; Mitochondria; Mitochondria, Liver; NADP; Oxygen Consumption; Permeability; Pyruvates; Rats; Transaminases | 1971 |
[Glutamate cycle, first step of nitrogen metabolism in Bacillus megaterium].
Topics: Alanine; Allosteric Regulation; Amino Acid Oxidoreductases; Ammonia; Aspartic Acid; Bacillus megaterium; Enzyme Repression; Glucose; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Ketoglutaric Acids; Lyases; Mutation; NAD; NADP; Nitrogen; Oxaloacetates; Oxidoreductases; Pyruvates; Transaminases | 1972 |
Incorporation of ammonium in amino acids by Trypanosoma cruzi.
Topics: Ammonia; Animals; Glutamate Dehydrogenase; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kinetics; NAD; NADP; Trypanosoma cruzi | 1980 |
The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme.
Topics: Animals; Carcinoma, Ehrlich Tumor; Female; Glutamates; Glutamic Acid; Glutamine; Kidney; Kinetics; Leukemia L1210; Liver Neoplasms, Experimental; Malate Dehydrogenase; Male; Mice; Mice, Inbred Strains; Mitochondria; Mitochondria, Liver; NAD; NADP; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thymoma; Thymus Neoplasms | 1984 |
The coupling of metabolic to secretory events in pancreatic islets. The cytosolic redox state.
Topics: Animals; Cytosol; Glutamine; In Vitro Techniques; Islets of Langerhans; Isocitrate Dehydrogenase; Leucine; Malate Dehydrogenase; Malates; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats | 1984 |
Regulation and function of glutamate synthase in Neurospora crassa.
Topics: Ammonia; Glutamate Synthase; Glutamates; Glutamine; Kinetics; Mutation; NAD; NADP; Neurospora; Neurospora crassa; Species Specificity; Transaminases | 1980 |
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic interaction of L-glutamine and 2-ketoisocaproate in pancreatic islets.
Topics: Animals; Drug Synergism; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Transaminases | 1981 |
The stimulus-secretion coupling of amino acid-induced insulin release. Influence of a nonmetabolized analog of leucine on the metabolism of glutamine in pancreatic islets.
Topics: Adenine Nucleotides; Amino Acids; Amino Acids, Cyclic; Animals; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; NAD; NADP; Oxidation-Reduction; Rats | 1982 |
Noncarbohydrate nutrients protect against alloxan-induced inhibition of insulin release.
Topics: Alloxan; Amino Acids; Animals; Glucose; Glutamine; Insulin; Islets of Langerhans; Keto Acids; Leucine; NAD; NADP; Rats; Time Factors | 1982 |
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine.
Topics: Animals; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Models, Biological; NAD; NADP; Rats | 1982 |
Effect of adrenaline and phorbol myristate acetate or bacterial lipopolysaccharide on stimulation of pathways of macrophage glucose, glutamine and O2 metabolism. Evidence for cyclic AMP-dependent protein kinase mediated inhibition of glucose-6-phosphate d
Topics: Animals; Bucladesine; Cell Membrane Permeability; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Digitonin; Epinephrine; Glucose; Glucosephosphate Dehydrogenase; Glutamine; Glycerol; Hydrogen Peroxide; In Vitro Techniques; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Malate Dehydrogenase; Male; Mycobacterium bovis; N-Formylmethionine Leucyl-Phenylalanine; NADP; Oxygen Consumption; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1995 |
Residues affecting the catalysis and inhibition of rat lens aldose reductase.
Topics: Aldehyde Reductase; Animals; Binding Sites; Blotting, Western; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lens, Crystalline; Mutagenesis, Site-Directed; NADP; Rats; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 1995 |
Changes in the NAD(P)H concentration caused by addition of nitrogenase 'switch-off' effectors in Rhodospirillum rubrum G-9, as measured by fluorescence.
Topics: Ammonia; Darkness; Glutamine; Light; NAD; NADP; Nitrogen Fixation; Nitrogenase; Oxidation-Reduction; Oxygen; Rhodospirillum rubrum; Spectrometry, Fluorescence | 1994 |
The pH-dependent behavior of catalytic activities of Azospirillum brasilense glutamate synthase and iodoacetamide modification of the enzyme provide evidence for a catalytic Cys-His ion pair.
Topics: Amino Acid Sequence; Ammonia; Azospirillum brasilense; Catalysis; Cysteine; Glutamate Synthase; Glutamine; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Ketoglutaric Acids; Kinetics; Molecular Sequence Data; NADP; Sequence Analysis | 1994 |
The role of reduced nicotinamide adenine dinucleotide phosphate in glucose- and temperature-dependent doxorubicin cytotoxicity.
Topics: Animals; Cell Survival; Culture Media; DNA Damage; Doxorubicin; Drug Resistance; Glucose; Glutamine; L Cells; Methylene Blue; Mice; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Temperature; Uridine | 1993 |
The role of glutamine as an energy source in the developing rat lung.
Topics: Animals; Female; Fibroblasts; Glutamine; Lung; NADP; Oxidation-Reduction; Pregnancy; Rats; Rats, Sprague-Dawley | 1996 |
Crystal structures of a ferredoxin: NADP+ reductase and of a complex with NADP+.
Topics: Anabaena; Arginine; Binding Sites; Crystallography, X-Ray; Ferredoxin-NADP Reductase; Glutamine; Lysine; Models, Structural; NADP; Protein Conformation; Protein Folding; Protein Structure, Secondary | 1996 |
Evidence for murine macrophage nitric oxide synthesis in the absence of exogenous L-arginine.
Topics: Animals; Arginine; Glucose; Glutamine; In Vitro Techniques; Islets of Langerhans; Macrophages; Mice; NADP; Nitric Oxide | 1996 |
Oxygen activation by cytochrome P450BM-3: effects of mutating an active site acidic residue.
Topics: Bacterial Proteins; Binding Sites; Cytochrome P-450 Enzyme System; Enzyme Activation; Glutamic Acid; Glutamine; Hydroxylation; Laurates; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Myristates; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxygen Consumption; Palmitates; Protein Structure, Secondary; Substrate Specificity | 1997 |
A glutamine 67--> histidine mutation in homotetrameric R67 dihydrofolate reductase results in four mutations per single active site pore and causes substantial substrate and cofactor inhibition.
Topics: Binding Sites; Calorimetry; Catalysis; Enzyme Inhibitors; Escherichia coli; Folic Acid; Glutamine; Histamine; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; NADP; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thermodynamics | 1997 |
Mechanisms of glutamate metabolic signaling in retinal glial (Müller) cells.
Topics: Ambystoma; Animals; Biosensing Techniques; Citric Acid Cycle; Flavin-Adenine Dinucleotide; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glycolysis; Lactic Acid; Microscopy, Fluorescence; NADP; Neuroglia; Neurons, Afferent; Quaternary Ammonium Compounds; Retina; Signal Transduction | 2000 |
Aromatic residues and neighboring Arg414 in the (6R)-5,6,7, 8-tetrahydro-L-biopterin binding site of full-length neuronal nitric-oxide synthase are crucial in catalysis and heme reduction with NADPH.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Binding Sites; Biopterins; Catalysis; Dimerization; Drosophila; Glutamine; Heme; Humans; Hydrogen Bonding; Leucine; Mice; Models, Molecular; Molecular Sequence Data; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Phenylalanine; Rats; Spectrophotometry, Atomic; Structure-Activity Relationship; Tryptophan | 2000 |
Delineation of the roles of amino acids involved in the catalytic functions of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase.
Topics: Arginine; Binding Sites; Catalysis; Conserved Sequence; Dimerization; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glutamine; Kinetics; Leuconostoc; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; NAD; NADP; Proline; Thermodynamics | 2000 |
Glutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesis.
Topics: Animals; Calcium; Cattle; Cells, Cultured; Endothelium, Vascular; Glucosamine; Glutamine; Models, Chemical; NADP; Nitric Oxide; Nitric Oxide Synthase; Pentose Phosphate Pathway | 2001 |
Evaluation by mutagenesis of the roles of His309, His315, and His319 in the coenzyme site of pig heart NADP-dependent isocitrate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Circular Dichroism; Escherichia coli; Ferrous Compounds; Glutamine; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Isocitrate Dehydrogenase; Isocitrates; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; NADP; Phenylalanine; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Swine | 2002 |
Properties of the recombinant ferredoxin-dependent glutamate synthase of Synechocystis PCC6803. Comparison with the Azospirillum brasilense NADPH-dependent enzyme and its isolated alpha subunit.
Topics: Amino Acid Oxidoreductases; Azospirillum brasilense; Catalysis; Cyanobacteria; Dithionite; Ferredoxins; Glutamic Acid; Glutaminase; Glutamine; Ketoglutaric Acids; NADP; Oxidation-Reduction; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry; Sulfites; Tetrazolium Salts; Titrimetry | 2002 |
Breaking symmetry: mutations engineered into R67 dihydrofolate reductase, a D2 symmetric homotetramer possessing a single active site pore.
Topics: Amino Acid Substitution; Binding Sites; Circular Dichroism; Gene Dosage; Genes, Bacterial; Genes, Synthetic; Glutamine; Histidine; Kinetics; Molecular Mimicry; Mutagenesis, Site-Directed; NADP; R Factors; Tandem Repeat Sequences; Tetrahydrofolate Dehydrogenase | 2002 |
Glutamine 132 in the NAD(H)-binding component of proton-translocating transhydrogenase tethers the nucleotides before hydride transfer.
Topics: Amino Acid Substitution; Asparagine; Bacterial Proteins; Binding Sites; Crystallization; Crystallography, X-Ray; Electron Transport; Glutamine; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; NADP Transhydrogenases; Protons; Recombinant Proteins; Rhodospirillum rubrum | 2003 |
[Enrichment and separation of a diphosphopyridine nucleotide specific and a triphosphopyridine nucleotide specific glutamine acid dehydrogenase from yeast].
Topics: Glutamine; NAD; NADP; Oxidoreductases; Rare Diseases; Retinal Degeneration; Retinal Detachment; Saccharomyces cerevisiae; Yeast, Dried | 1957 |
PLASMA AMINO ACID PATTERNS IN ALCOHOLISM: THE EFFECTS OF ETHANOL LOADING.
Topics: Alanine; Alcoholism; Amino Acids; Autoanalysis; Biomedical Research; Blood; Ethanol; Genetics, Medical; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Methionine; NAD; NADP; Proline; Proteins; Serine; Toxicology; Valine | 1964 |
THE CONVERSION OF SHIKIMIC ACID TO ANTHRANILIC ACID BY EXTRACTS OF NEUROSPORA CRASSA.
Topics: Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Escherichia coli; Glutamine; Ligases; Magnesium; NADP; Neurospora; Neurospora crassa; ortho-Aminobenzoates; Pyruvates; Research; Shikimic Acid; Spectrum Analysis | 1965 |
Non-invasive glucose monitoring by NAD(P)H autofluorescence spectroscopy in fibroblasts and adipocytes: a model for skin glucose sensing.
Topics: 3-Hydroxybutyric Acid; 3T3-L1 Cells; Adipocytes; Animals; Biosensing Techniques; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Fibroblasts; Glucose; Glutamine; Islets of Langerhans; Mice; Mitochondria; NADP; Palmitic Acid; Rhodamine 123; Sensitivity and Specificity; Spectrometry, Fluorescence | 2003 |
Role of methionine-13 in the catalytic mechanism of 6-phosphogluconate dehydrogenase from sheep liver.
Topics: Amino Acid Sequence; Animals; Catalysis; Circular Dichroism; Cysteine; Deuterium Exchange Measurement; Glutamine; Kinetics; Liver; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Phenylalanine; Phosphogluconate Dehydrogenase; Sheep | 2005 |
Release of oxidized plastocyanin from photosystem I limits electron transfer between photosystem I and cytochrome b6f complex in vivo.
Topics: Animals; Binding Sites; Chlamydomonas; Cytochrome b6f Complex; Dose-Response Relationship, Drug; Electrons; Glutamic Acid; Glutamine; Kinetics; Mutation; NADP; Oxygen; Phenotype; Photosynthesis; Photosystem I Protein Complex; Plastocyanin; Protein Binding; Serine; Spectrophotometry; Time Factors; Tryptophan | 2005 |
Determinants of the dual cofactor specificity and substrate cooperativity of the human mitochondrial NAD(P)+-dependent malic enzyme: functional roles of glutamine 362.
Topics: Adenosine Triphosphate; Allosteric Site; Catalysis; Fumarates; Glutamine; Humans; Kinetics; Lysine; Malate Dehydrogenase; Mitochondria; NADP; Protein Binding; Substrate Specificity; Thermodynamics | 2006 |
The fate of glucose during the period of decreased metabolism after fluid percussion injury: a 13C NMR study.
Topics: Animals; Brain Injuries; Carbon Isotopes; Cerebral Cortex; Down-Regulation; Free Radicals; Glucose; Glutamine; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Male; NADP; Oxidative Phosphorylation; Oxidative Stress; Pentose Phosphate Pathway; Rats; Rats, Sprague-Dawley; Time Factors; Wounds, Nonpenetrating | 2007 |
Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Echinococcosis, Pulmonary; Erythrocytes; Female; Glutamic Acid; Glutamine; Hemolysis; Humans; Hydrogen-Ion Concentration; Male; NADP; Nitric Oxide; Oxidation-Reduction; Tricuspid Valve Insufficiency | 2008 |
The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion.
Topics: Animals; Cytosol; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Ketoglutaric Acids; Membrane Transport Proteins; Mitochondria; Models, Biological; NADP; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
Topics: Analysis of Variance; Animals; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Guinea Pigs; Mice; Myelin Basic Protein; NAD; NADP; Nitric Oxide Synthase Type II; Oxidative Stress; Tandem Mass Spectrometry | 2011 |
Reductive carboxylation supports growth in tumour cells with defective mitochondria.
Topics: Acetyl Coenzyme A; Animals; Carcinoma, Renal Cell; Cell Hypoxia; Cell Line, Tumor; Citric Acid; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Fumarate Hydratase; Glucose; Glutamine; Humans; Isocitrate Dehydrogenase; Kidney Neoplasms; Mice; Mitochondria; NADP; Neoplasms | 2011 |
Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide.
Topics: Asparagine; Bacillus megaterium; Catalysis; Cytochrome P-450 Enzyme System; Diclofenac; Drug Discovery; Escherichia coli; Glutamine; Glycine; Histidine; Humans; Hydroxylation; Ibuprofen; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Tolbutamide | 2012 |
Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence.
Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Cell Line; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Doxorubicin; Gene Expression Regulation; Gene Knockdown Techniques; Gene Silencing; Glucose; Glutamine; HCT116 Cells; Humans; Lipids; Malate Dehydrogenase; Malate Dehydrogenase (NADP+); Mice; NADP; Protein Binding; Tumor Suppressor Protein p53 | 2013 |
Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance.
Topics: Cell Proliferation; Glutamine; Humans; Metabolic Networks and Pathways; NADP; Oxidation-Reduction; Pancreatic Neoplasms | 2013 |
FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells.
Topics: Animals; Animals, Newborn; Cells, Cultured; Forkhead Box Protein O3; Forkhead Transcription Factors; Glucose; Glutamine; Metabolic Networks and Pathways; Mice; Mice, Transgenic; NADP; Neural Stem Cells; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Reactive Oxygen Species; TOR Serine-Threonine Kinases | 2013 |
Hypoxia-resistant profile implies vulnerability of cancer stem cells to physiological agents, which suggests new therapeutic targets.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Citric Acid Cycle; Glutamine; Humans; Leukemia; Liver Neoplasms, Experimental; Melanoma; Metabolic Networks and Pathways; Mitosis; NADP; Neoplastic Stem Cells; Oxidation-Reduction; Pyruvic Acid; Rats; Rats, Wistar; Tetrahydrofolates | 2014 |
Mutant KRAS associated malic enzyme 1 expression is a predictive marker for radiation therapy response in non-small cell lung cancer.
Topics: Animals; Aspartate Aminotransferase, Cytoplasmic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Databases, Factual; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Glutamine; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Malate Dehydrogenase; Mice; Mice, Transgenic; Mutation, Missense; NADP; Neoplasm Proteins; Oxidation-Reduction; Point Mutation; Prognosis; Radiation Tolerance; Recombinant Fusion Proteins; RNA Interference; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering; Tumor Stem Cell Assay; Up-Regulation | 2015 |
An RNA interference knock-down of nitrate reductase enhances lipid biosynthesis in the diatom Phaeodactylum tricornutum.
Topics: Carbon; Diatoms; Gene Expression Profiling; Gene Expression Regulation; Gene Knockdown Techniques; Glutamic Acid; Glutamine; Lipid Metabolism; Malonyl Coenzyme A; Metabolic Networks and Pathways; NADP; Nitrate Reductase; Nitrates; Nitrogen; Oxidation-Reduction; Photosynthesis; RNA Interference; Stress, Physiological | 2015 |
Inhibition of Mitochondrial Complex II by the Anticancer Agent Lonidamine.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Citric Acid Cycle; Diacetyl; Electron Transport Complex II; Fumarates; Glutamine; Glutathione; Humans; Indazoles; Malates; Melanoma; Metabolic Flux Analysis; Mitochondria; Models, Biological; NADP; Naphthalenes; Oxidation-Reduction; Pentose Phosphate Pathway; Reactive Oxygen Species; Succinic Acid | 2016 |
Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress.
Topics: Animals; Apigenin; Apoptosis; Benzophenanthridines; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Glutamine; Humans; Lung Neoplasms; Mice; NADP; Oxidative Stress; Reactive Oxygen Species | 2016 |
Reductive carboxylation supports redox homeostasis during anchorage-independent growth.
Topics: Cell Adhesion; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Citric Acid; Contact Inhibition; Cytosol; Extracellular Matrix; Glucose; Glutamic Acid; Glutamine; Homeostasis; Humans; Isocitrate Dehydrogenase; Isocitrates; Mitochondria; NADP; Neoplasms; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Spheroids, Cellular | 2016 |
Metabolic shift toward oxidative phosphorylation in docetaxel resistant prostate cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Coculture Techniques; Docetaxel; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Fibroblasts; Glucose; Glutamine; Glycolysis; Humans; Male; Mitochondria; NADP; Oxidative Phosphorylation; Phenotype; Prostate; Prostatic Neoplasms; Reactive Oxygen Species; Taxoids | 2016 |
Arginine Methylation of MDH1 by CARM1 Inhibits Glutamine Metabolism and Suppresses Pancreatic Cancer.
Topics: Arginine; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glutamine; HEK293 Cells; Humans; Malate Dehydrogenase (NADP+); Methylation; Mitochondria; Models, Molecular; NADP; Oxidation-Reduction; Pancreatic Neoplasms; Protein Multimerization; Protein Structure, Secondary; Protein-Arginine N-Methyltransferases; RNA, Small Interfering; Signal Transduction | 2016 |
The complex allosteric and redox regulation of the fumarate hydratase and malate dehydratase reactions of Arabidopsis thaliana Fumarase 1 and 2 gives clues for understanding the massive accumulation of fumarate.
Topics: Allosteric Regulation; Arabidopsis; Arabidopsis Proteins; Asparagine; Binding Sites; Evolution, Molecular; Fumarate Hydratase; Fumarates; Gene Expression; Gene Expression Regulation, Plant; Glutamine; Hydrogen-Ion Concentration; Kinetics; Malate Dehydrogenase; Models, Molecular; NADP; Oxaloacetic Acid; Oxidation-Reduction; Phylogeny; Protein Aggregates; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Recombinant Proteins; Substrate Specificity | 2018 |
Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; ERRalpha Estrogen-Related Receptor; Female; Gene Expression Regulation, Neoplastic; Glucosephosphate Dehydrogenase; Glutaminase; Glutamine; Glycolysis; Homeostasis; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; NADP; Oxidation-Reduction; Pentose Phosphate Pathway; Pyruvic Acid; Receptors, Estrogen; Tumor Cells, Cultured | 2019 |
Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism.
Topics: Antioxidants; Antiporters; Cadaverine; Glutamine; Glutathione; Lysine; NADP; Organic Cation Transport Proteins; Ornithine Decarboxylase; Oxidants; Polyamines; Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2019 |
p53-dependent glutamine usage determines susceptibility to oxidative stress in radioresistant head and neck cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Glucose; Glutaminase; Glutamine; Glutathione; Glycolysis; Head and Neck Neoplasms; Humans; NADP; Oxidation-Reduction; Oxidative Stress; Radiation Tolerance; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53 | 2021 |
Pancreatic β cells put the glutamine engine in reverse.
Topics: Glucose; Glutamine; Insulin Secretion; Insulin-Secreting Cells; NADP | 2021 |
SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Glutathione; Heterografts; Humans; Male; Mice; Mice, Nude; NADP; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Prognosis; Protein Processing, Post-Translational; Signal Transduction; Succinate-CoA Ligases; Succinic Acid; Survival Analysis | 2021 |
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions.
Topics: Animals; Glucose; Glutamine; Lactic Acid; Mice; NADP; Neoplasms; Pentose Phosphate Pathway | 2021 |
Serine catabolism generates liver NADPH and supports hepatic lipogenesis.
Topics: Acetyl Coenzyme A; Adipose Tissue; Aminohydrolases; Animals; Fatty Acids; Female; Folic Acid; Formate-Tetrahydrofolate Ligase; Glutamine; Glycine Hydroxymethyltransferase; Hepatocytes; Lipid Metabolism; Lipogenesis; Liver; Male; Metabolic Networks and Pathways; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Multienzyme Complexes; NADP; Oxidative Phosphorylation; Oxidoreductases Acting on CH-NH Group Donors; Serine | 2021 |
Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells.
Topics: Animals; Glucosephosphate Dehydrogenase; Glutamine; Humans; Melanoma; Mice; Mice, Inbred NOD; NADP; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Reactive Oxygen Species | 2022 |
Lithocholic acid inhibits gallbladder cancer proliferation through interfering glutaminase-mediated glutamine metabolism.
Topics: Bile Acids and Salts; Cell Line, Tumor; Cell Proliferation; Gallbladder Neoplasms; Glutaminase; Glutamine; Glutathione Disulfide; Humans; Lipids; Lithocholic Acid; NADP; Reactive Oxygen Species | 2022 |
Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic mice.
Topics: Animals; Glucosephosphate Dehydrogenase; Glutamine; Goblet Cells; Mice; Mucus; NADP | 2023 |
Construct a synthetic Entner-Doudoroff pathway in Bacillus licheniformis for enhancing lichenysin production.
Topics: Aspartic Acid; Bacillus licheniformis; Fatty Acids; Glutamine; Leucine; NADP; Peptides, Cyclic; Pyruvates; Valine | 2023 |