glutamine and deoxyglucose

glutamine has been researched along with deoxyglucose in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199015 (33.33)18.7374
1990's7 (15.56)18.2507
2000's6 (13.33)29.6817
2010's14 (31.11)24.3611
2020's3 (6.67)2.80

Authors

AuthorsStudies
Campbell, JA; Edwards, JG; Robson, RT; Vicker, MG1
Christopher, CW; Kalckar, HM; Ullrey, D1
Armour, R; Baldwin, JH; Holley, RW1
Chang, TW; Goldberg, AL1
Prouty, WF1
Downs, SM; Fagbohun, CF1
Brookes, N1
DeJoseph, MR; Hawkins, RA1
Kagawa, S; Matsuoka, A; Nakao-Yamashita, K; Wakabayashi, S1
Brkljac, O; Jerance, D; Kovacević, Z1
Lanks, KW1
Murnane, JM; Ritter, S1
Clegg, JS; Gordon, EP1
Bailey, A; Steigerwalt, RW; Williams, JA1
Goldstein, G; Guskey, LE1
Faik, P; Morgan, MJ1
Jha, B; Kagawa, S; Matsuoka, A; Nakao, K; Shimizu, S; Wakabayashi, S; Yoshida, K1
Hussain, AA; Oraedu, AC; Taj, M; Voaden, MJ1
Hashiramoto, M; Kasuga, M; Kazumi, T; Kishimoto, M; Shii, K; Yonezawa, K1
Grdisa, M; Johnstone, RM; Mathew, A; Robbins, PJ; White, MK1
Beguinot, F; Beguinot, L; Di Finizio, B; Ferrara, A; Formisano, P; Miele, C; Petruzziello, A; Riccardi, G1
Blekkenhorst, GH; Hunter, AJ1
Fukatsu, K; Furukawa, S; Han, I; Hidemura, A; Ikeda, S; Inoue, T; Matsuda, T; Muto, T; Saito, H1
Chan, BS; Endo, S; Kanai, N; Schuster, VL1
Healy, DA; Newsholme, P; Watson, RW1
Gibbs, ME; Hertz, L; Lloyd, HG; Santa, T1
Drozdov, I; Gustafsson, BI; Hauso, O; Kidd, M; Modlin, IM; Pfragner, R1
Bachoo, RG; Bachoo, RM; Dang, T; DeBerardinis, RJ; McDonald, JG; Sudderth, J; Yang, C1
Acuña, AI; Angulo, C; Beltrán, FA; Castro, MA; Concha, II; Miró, MP1
Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G1
Baloh, RH; Milbrandt, J; Misko, AL; Sasaki, Y; Tuck, E1
Akulov, AE; Koptug, IV; Moshkin, MP; Petrovskiĭ, DV; Petrovskiĭ, ED; Saĭk, OV; Savelov, AA1
Adamik, J; Auron, PE; Beasley, FC; Bernard, NJ; Caffrey, BE; Clish, C; Corr, SC; Cummins, E; Curtis, AM; Foley, NH; Frezza, C; Gardet, A; Goel, G; Gottlieb, E; Haneklaus, M; Jany, SS; Kelly, B; Kelly, VP; Lin, H; Masters, SL; McGettrick, AF; Nizet, V; O'Neill, LA; Palsson-McDermott, EM; Pierce, K; Tannahill, GM; Taylor, CT; Tong, Z; Walmsley, S; Whyte, M; Xavier, RJ; Zheng, L1
Fan, Y; Li, Z; Wu, H; Yang, P; Zhang, L1
López-Villegas, EO; Moreno-Altamirano, MM; Rodríguez-Espinosa, O; Rojas-Espinosa, O; Sánchez-García, FJ1
Andrade-Oliveira, V; Bowman, CE; Brandacher, G; Cheng, CH; Furtmüller, GJ; Lee, CF; Lo, YC; Oh, B; Powell, JD; Slusher, BS; Thomas, AG; Wolfgang, MJ1
Baudy, AR; Daemen, A; Evangelista, M; Gao, M; Haley, B; Hatzivassiliou, G; Pusapati, RV; Sandoval, W; Settleman, J; Wilson, C1
Chen, H; Hu, M; Ni, S; Shen, N; Sun, L; Wang, J; Yang, X; Zhang, T; Zheng, K1
Asmis, R; Downs, K; Goins, B; Jerabek, PA; Lai, Y; Nguyen, HN; Sadeghi, MM; Short, JD; Tavakoli, S; Toczek, J1
Kitamura, J; Morishima, H; Shinohara, Y; Takahashi, N; Takahashi, T; Washio, J1
Alsady, M; Baumgarten, R; Bekkenkamp-Grovenstein, M; Carmone, C; de Groot, T; Deen, PMT; Engelke, U; Korstanje, R; Kortenoeven, MLA; Neijman, K; Wevers, R1
Mathews, EH; Mathews, GE; Meyer, AA1
Huang, H; Li, S; Liu, Y; Luo, Z; Ma, W; Pardeshi, A; Sun, J; Wan, Z; Xu, J; Zhang, Z1
Chevet, E; Eldering, E; Favaro, F; Iurlaro, R; Lucendo, E; Majem, B; Marchetti, S; Muñoz-Pinedo, C; Nadal, E; Püschel, F; Redondo-Pedraza, J; Ricci, JE1
Becker, M; Bedke, J; Büttner, FA; Fend, F; Haag, M; Hennenlotter, J; Hofmann, U; Klumpp, V; Leuthold, P; Menig, LS; Rausch, S; Reustle, A; Schaeffeler, E; Scharpf, M; Schmees, C; Schwab, M; Stenzl, A; Stühler, V; Winter, S1

Reviews

1 review(s) available for glutamine and deoxyglucose

ArticleYear
Carbohydrate metabolism in cultured animal cells.
    Bioscience reports, 1981, Volume: 1, Issue:9

    Topics: 3-O-Methylglucose; Animals; Biological Transport; Carbohydrate Metabolism; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Viral; Cells, Cultured; Citric Acid Cycle; Deoxyglucose; Energy Metabolism; Glucose; Glutamine; Glycolysis; Hexokinase; Hexoses; Humans; Methylglucosides; Mutation; Oxygen Consumption; Pentosephosphates; Phosphofructokinase-1; Phosphorylation; Pyruvate Kinase; Teratoma

1981

Other Studies

44 other study(ies) available for glutamine and deoxyglucose

ArticleYear
Trypsinized BHK21 cells aggregate in the presence of metabolic inhibitors and in the absence of divalent cations.
    Journal of cell science, 1975, Volume: 19, Issue:3

    Topics: 4-Chloromercuribenzenesulfonate; Azaserine; Bucladesine; Cations, Divalent; Cell Adhesion; Cell Aggregation; Cell Line; Cobalt; Cyanides; Cycloheximide; Cytochalasin B; Deoxyglucose; Electron Transport; Fluorides; Glucose; Glutamine; Glycolysis; Hexosamines; Manganese; Protein Biosynthesis; Rotenone; Sodium; Temperature; Trypsin

1975
Neoplastic potentials and regulation of uptake and nutrients. II. Inverse regulation of uptake of hexose and amino acid analogues in the neoplastic GIV line.
    Journal of cellular physiology, 1976, Volume: 89, Issue:4

    Topics: Amino Acids; Animals; Biological Transport, Active; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cycloleucine; Deoxyglucose; Galactose; Genetic Variation; Glucose; Glutamine; Hexoses; Polyomavirus; Stereoisomerism

1976
Density-dependent regulation of growth of BSC-1 cells in cell culture: control of growth by low molecular weight nutrients.
    Proceedings of the National Academy of Sciences of the United States of America, 1978, Volume: 75, Issue:1

    Topics: Biological Transport; Cell Division; Cells, Cultured; Contact Inhibition; Culture Media; Deoxyglucose; Epithelium; Glucose; Glutamine; Methylglucosides

1978
The origin of alanine produced in skeletal muscle.
    The Journal of biological chemistry, 1978, May-25, Volume: 253, Issue:10

    Topics: Alanine; Amino Acids; Ammonia; Animals; Deoxyglucose; Diaphragm; Glucose; Glutamine; Male; Muscles; Pyruvates; Rats

1978
Ornithine decarboxylase inactivation in HeLa cells.
    Journal of cellular physiology, 1976, Volume: 89, Issue:1

    Topics: Carboxy-Lyases; Cyanides; Cycloheximide; Deoxyglucose; Dinitrophenols; Enzyme Induction; Glutamine; HeLa Cells; Insulin; Kinetics; Ornithine Decarboxylase; Puromycin; Tosylphenylalanyl Chloromethyl Ketone

1976
Requirement for glucose in ligand-stimulated meiotic maturation of cumulus cell-enclosed mouse oocytes.
    Journal of reproduction and fertility, 1992, Volume: 96, Issue:2

    Topics: 3-O-Methylglucose; Animals; Bucladesine; Cell Survival; Concanavalin A; Culture Media; Deoxyglucose; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Glucose; Glutamine; Hexoses; In Vitro Techniques; Ligands; Meiosis; Methylglucosides; Mice; Mice, Inbred C57BL; Oocytes; Oogenesis; Phloretin; Pyruvates; Pyruvic Acid; Time Factors

1992
In vitro evidence for the role of glutamate in the CNS toxicity of mercury.
    Toxicology, 1992, Dec-04, Volume: 76, Issue:3

    Topics: Animals; Astrocytes; Cell Survival; Cells, Cultured; Central Nervous System Diseases; Deoxyglucose; Extracellular Space; Glutamates; Glutamic Acid; Glutamine; Mercury; Mice; Models, Biological; Neurons; Photomicrography; Silver Staining; Spinal Cord; Tritium

1992
Glucose consumption decreases throughout the brain only hours after portacaval shunting.
    The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 1

    Topics: Animals; Autoradiography; Blood Glucose; Body Weight; Brain; Carbon Radioisotopes; Deoxyglucose; Glucose; Glutamine; Liver; Organ Size; Organ Specificity; Portacaval Shunt, Surgical; Rats; Reference Values

1991
Maintenance of pancreatic endocrine cells of the neonatal rat: Part XIII--Effect of 2-deoxyglucose and iodoacetic acid on the functional maturation of neonatal rat B cells.
    Indian journal of biochemistry & biophysics, 1988, Volume: 25, Issue:5

    Topics: Animals; Animals, Newborn; Deoxy Sugars; Deoxyglucose; Glucose; Glutamine; Insulin; Insulin Secretion; Iodoacetates; Iodoacetic Acid; Islets of Langerhans; Oxidation-Reduction; Rats

1988
The role of glutamine oxidation and the purine nucleotide cycle for adaptation of tumour energetics to the transition from the anaerobic to the aerobic state.
    The Biochemical journal, 1988, Jun-01, Volume: 252, Issue:2

    Topics: Adenine Nucleotides; Aerobiosis; Anaerobiosis; Animals; Carcinoma, Ehrlich Tumor; Deoxyglucose; Energy Metabolism; Glutamine; Glycine; Inosine; Purine Nucleotides; Rotenone; Tumor Cells, Cultured

1988
Studies on the mechanism by which glutamine and heat shock increase lactate synthesis by L929 cells in the presence of insulin.
    Journal of cellular physiology, 1986, Volume: 129, Issue:3

    Topics: 3-O-Methylglucose; Aminooxyacetic Acid; Cell Line; Deoxyglucose; Glutamine; Glycolysis; Hot Temperature; Insulin; Kinetics; Lactates; Lactic Acid; Methylglucosides; Pyruvates; Pyruvic Acid; Transaminases

1986
Alloxan-induced glucoprivic feeding deficits are blocked by D-glucose and amygdalin.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:3

    Topics: Alloxan; Amygdalin; Animals; Blood Glucose; Body Weight; Deoxy Sugars; Deoxyglucose; Feeding Behavior; Glucose; Glutamine; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Time Factors

1985
Respiratory metabolism of L-929 cells at different water contents and volumes.
    Journal of cellular physiology, 1985, Volume: 124, Issue:2

    Topics: Animals; Culture Media; Deoxyglucose; Fibroblasts; Glucose; Glutamine; Iodoacetates; Iodoacetic Acid; Mice; Oxygen Consumption; Pyruvates; Pyruvic Acid; Sorbitol; Time Factors; Water

1985
Effects of proglumide on pancreatic acinar cell function.
    Digestion, 1983, Volume: 27, Issue:4

    Topics: Amylases; Animals; Cholecystokinin; Deoxyglucose; Glutamine; Islets of Langerhans; Male; Mice; Proglumide; Receptor, Insulin; Receptors, Cell Surface; Receptors, Cholecystokinin

1983
Poliovirus and vesicular stomatitis virus replication in the presence of 6-diazo-5-oxo-L-norleucine or 2-deoxy-D-glucose.
    Journal of medical virology, 1984, Volume: 14, Issue:2

    Topics: Animals; Azo Compounds; Cell Line; Chlorocebus aethiops; Deoxy Sugars; Deoxyglucose; Diazooxonorleucine; Glutamine; Humans; Kinetics; Nucleotides; Poliovirus; RNA; RNA, Viral; Tunicamycin; Uridine; Vesicular stomatitis Indiana virus; Viral Plaque Assay; Virus Replication

1984
The effect of 2-deoxy-D-glucose on insulin release by neonatal rat B cells in culture.
    Endocrinologia japonica, 1983, Volume: 30, Issue:2

    Topics: Animals; Animals, Newborn; Cells, Cultured; Deoxy Sugars; Deoxyglucose; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Rats; Rats, Inbred Strains; Valine

1983
Light and retinal metabolism.
    Biochemical Society transactions, 1983, Volume: 11, Issue:6

    Topics: Aminocaproates; Animals; Dark Adaptation; Deoxyglucose; Female; Glutamine; Light; Rats; Rats, Inbred Strains; Retina; Vigabatrin

1983
Substitution of glutamine for arginine 1131. A newly identified mutation in the catalytic loop of the tyrosine kinase domain of the human insulin receptor.
    The Journal of biological chemistry, 1994, Apr-15, Volume: 269, Issue:15

    Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Cell Division; CHO Cells; Cricetinae; Deoxyglucose; DNA; DNA Primers; Down-Regulation; Exons; Female; Glutamine; Humans; Insulin; Kinetics; Male; Middle Aged; Molecular Sequence Data; Myelin Basic Protein; Pedigree; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Polymerase Chain Reaction; Receptor, Insulin; Thymidine; Transfection

1994
Loss of glucose transporters is an early event in differentiation of HD3 cells.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: 3-O-Methylglucose; Affinity Labels; Animals; Biological Transport, Active; Blood Proteins; Carrier Proteins; Cell Differentiation; Cell Division; Cell Line; Chickens; Deoxyglucose; Erythroblasts; Gene Expression; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Glutamine; Kinetics; Membrane Proteins; Methylglucosides; Monosaccharide Transport Proteins; Nerve Tissue Proteins; Nucleoside Transport Proteins; Reticulocytes; RNA, Messenger; Sheep; Thioinosine; Time Factors

1994
Defective insulin action in fibroblasts from noninsulin-dependent diabetes mellitus patients with Gln1152 insulin receptor mutation.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 77, Issue:2

    Topics: Adult; Aminobutyrates; Cells, Cultured; Cytochalasin B; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Fibroblasts; Glucose; Glutamine; Glycogen Synthase; Humans; Insulin; Male; Middle Aged; Phosphorylation; Phosphotransferases; Point Mutation; Receptor, Insulin; Tetradecanoylphorbol Acetate

1993
The effects of 2-deoxyglucose and amino-oxyacetic acid on the radiation response of mammalian cells in vitro.
    International journal of radiation biology, 1998, Volume: 73, Issue:3

    Topics: Aminooxyacetic Acid; Animals; Antimetabolites; Cell Survival; CHO Cells; Cricetinae; Culture Media; Deoxyglucose; DNA Repair; Energy Metabolism; Enzyme Inhibitors; Glucose; Glutamine; Glycolysis; Lactates; Time Factors

1998
Relative effects of glucose and glutamine on reactive oxygen intermediate production by neutrophils.
    Shock (Augusta, Ga.), 2000, Volume: 13, Issue:4

    Topics: Cells, Cultured; Deoxyglucose; Diploidy; Glucose; Glutamine; Humans; Kinetics; Neutrophils; Reactive Oxygen Species; Reference Values

2000
Identification of lactate as a driving force for prostanoid transport by prostaglandin transporter PGT.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:6

    Topics: Antiporters; Biological Transport; Deoxyglucose; Dinoprostone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression; Glucose; Glutamine; Glycolysis; HeLa Cells; Humans; Lactic Acid; Organic Anion Transporters; Oxidative Phosphorylation; Prostaglandins; Transfection

2002
Glucose, but not glutamine, protects against spontaneous and anti-Fas antibody-induced apoptosis in human neutrophils.
    Clinical science (London, England : 1979), 2002, Volume: 103, Issue:2

    Topics: Adenosine Triphosphate; Analysis of Variance; Apoptosis; Cells, Cultured; Deoxyglucose; fas Receptor; Glucose; Glutamine; Humans; Intracellular Fluid; Neutrophils

2002
Glycogen is a preferred glutamate precursor during learning in 1-day-old chick: biochemical and behavioral evidence.
    Journal of neuroscience research, 2007, Nov-15, Volume: 85, Issue:15

    Topics: Animals; Animals, Newborn; Arabinose; Aspartic Acid; Astrocytes; Behavior, Animal; Brain; Brain Chemistry; Chickens; Chromatography, High Pressure Liquid; Deoxyglucose; Glutamic Acid; Glutamine; Glycogen; Imino Furanoses; Learning; Neurons; Sugar Alcohols

2007
Luminal regulation of normal and neoplastic human EC cell serotonin release is mediated by bile salts, amines, tastants, and olfactants.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 295, Issue:2

    Topics: Amino Acid Transport System A; Bile Acids and Salts; Caffeine; Carcinoid Tumor; Cell Line, Tumor; Deoxycholic Acid; Deoxyglucose; Enterochromaffin Cells; Extracellular Signal-Regulated MAP Kinases; Glucose Transport Proteins, Facilitative; Glutamine; Humans; Intestinal Neoplasms; Intestine, Small; Organic Anion Transporters, Sodium-Dependent; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate; Receptors, Odorant; Serotonin; Sodium-Glucose Transporter 1; Somatostatin; Sucrose; Symporters; Tyrosine

2008
Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling.
    Cancer research, 2009, Oct-15, Volume: 69, Issue:20

    Topics: Animals; Blotting, Western; Cell Line, Transformed; Cell Line, Tumor; Cell Survival; Citric Acid Cycle; Deoxyglucose; Gas Chromatography-Mass Spectrometry; Glioblastoma; Glucose; Glutamate Dehydrogenase; Glutamine; Glycolysis; Humans; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Mice; Mitochondria; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; RNA, Small Interfering; Signal Transduction

2009
Ascorbic acid-dependent GLUT3 inhibition is a critical step for switching neuronal metabolism.
    Journal of cellular physiology, 2011, Volume: 226, Issue:12

    Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Ascorbic Acid; Astrocytes; Cell Line, Tumor; Cerebral Cortex; Deoxyglucose; Dose-Response Relationship, Drug; Glioma; Glucose Transporter Type 3; Glutamine; Kinetics; Microscopy, Confocal; Neurons; Rats; Rats, Wistar; Recombinant Proteins; RNA Interference; Transfection

2011
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells.
    Cancer, 2011, Jul-01, Volume: 117, Issue:13

    Topics: Adenosine Triphosphate; Carcinoma; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Deoxyglucose; Disease Progression; Genes, p53; Glucose; Glutamine; Head and Neck Neoplasms; Humans; Lactic Acid; Mass Spectrometry; Metabolomics; Metformin; Neoplasms, Squamous Cell; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Tumor Suppressor Protein p53

2011
Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Mar-21, Volume: 32, Issue:12

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Arginine; Axons; Calcium; Deoxyglucose; Embryo, Mammalian; Fluoresceins; Ganglia, Spinal; Gene Expression Regulation; Glutamine; Green Fluorescent Proteins; GTP Phosphohydrolases; Humans; Mitochondria; Mitochondrial Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Point Mutation; Rats; Reactive Oxygen Species; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Transfection

2012
[Magnetic resonance spectroscopy of metabolic changes in mice brain after 2-deoxy-D-glucose injection].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2012, Volume: 98, Issue:10

    Topics: Animals; Aspartic Acid; Brain; Choline; Deoxyglucose; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycolysis; Humans; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Male; Mice; Neurodegenerative Diseases; Radiography

2012
Succinate is an inflammatory signal that induces IL-1β through HIF-1α.
    Nature, 2013, Apr-11, Volume: 496, Issue:7444

    Topics: Animals; Bone Marrow Cells; Citric Acid Cycle; Deoxyglucose; Down-Regulation; gamma-Aminobutyric Acid; Genes, Mitochondrial; Glutamine; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunity, Innate; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Signal Transduction; Succinic Acid; Up-Regulation

2013
PKM2 depletion induces the compensation of glutaminolysis through β-catenin/c-Myc pathway in tumor cells.
    Cellular signalling, 2014, Volume: 26, Issue:11

    Topics: Antimetabolites; beta Catenin; Carrier Proteins; Cell Survival; Colonic Neoplasms; Deoxyglucose; Glutamine; Glycolysis; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Membrane Proteins; MicroRNAs; Proto-Oncogene Proteins c-myc; Pyruvate Kinase; RNA, Neoplasm; Signal Transduction; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2014
Metabolic requirements for neutrophil extracellular traps formation.
    Immunology, 2015, Volume: 145, Issue:2

    Topics: Carcinogens; Deoxyglucose; Enzyme Inhibitors; Extracellular Traps; Glucose; Glucose Transporter Type 1; Glutamine; Glycolysis; Humans; Neutrophils; Tetradecanoylphorbol Acetate

2015
Preventing Allograft Rejection by Targeting Immune Metabolism.
    Cell reports, 2015, Oct-27, Volume: 13, Issue:4

    Topics: Allografts; Animals; CD8-Positive T-Lymphocytes; Cells, Cultured; Deoxyglucose; Diazooxonorleucine; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glutamine; Glycolysis; Graft Rejection; Heart Transplantation; Metformin; Mice; Mice, Inbred BALB C; Mice, Transgenic; Phosphorylation; T-Lymphocytes, Regulatory

2015
mTORC1-Dependent Metabolic Reprogramming Underlies Escape from Glycolysis Addiction in Cancer Cells.
    Cancer cell, 2016, Apr-11, Volume: 29, Issue:4

    Topics: Adenosine Triphosphate; Animals; Carcinoma; Cell Line, Tumor; Citric Acid Cycle; Combined Modality Therapy; Cytokines; Deoxyglucose; Drug Resistance, Neoplasm; Drug Synergism; Energy Metabolism; Everolimus; Female; Glucose-6-Phosphate Isomerase; Glutaminase; Glutamine; Glycolysis; Hep G2 Cells; Humans; Mechanistic Target of Rapamycin Complex 1; Metabolomics; Mice; Mice, Nude; Molecular Targeted Therapy; Multiprotein Complexes; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Pentose Phosphate Pathway; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; RNA, Small Interfering; TOR Serine-Threonine Kinases; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2016
Global and targeted metabolomics of synovial fluid discovers special osteoarthritis metabolites.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017, Volume: 35, Issue:9

    Topics: Arthritis, Rheumatoid; Case-Control Studies; Deoxyglucose; Female; Gluconates; Glutamine; Humans; Lactones; Male; Metabolome; Metabolomics; Middle Aged; Osteoarthritis, Knee; Synovial Fluid

2017
Characterization of Macrophage Polarization States Using Combined Measurement of 2-Deoxyglucose and Glutamine Accumulation: Implications for Imaging of Atherosclerosis.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:10

    Topics: Animals; Aorta; Atherosclerosis; Autoradiography; Deoxyglucose; Fluorodeoxyglucose F18; Glutamine; Macrophages; Mice; Plaque, Atherosclerotic; Positron-Emission Tomography

2017
Real-time monitoring system for evaluating the acid-producing activity of oral squamous cell carcinoma cells at different environmental pH.
    Scientific reports, 2017, 08-30, Volume: 7, Issue:1

    Topics: Acids; Ammonia; Antimetabolites; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Deoxyglucose; Glucose; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Monitoring, Physiologic; Mouth Neoplasms

2017
Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells.
    American journal of physiology. Renal physiology, 2018, 02-01, Volume: 314, Issue:2

    Topics: Acetazolamide; Animals; Antimanic Agents; Aquaporin 2; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line; Deoxyglucose; Diabetes Insipidus, Nephrogenic; Epithelial Sodium Channels; Female; Glutamine; Glycolysis; Kidney Tubules, Collecting; Lactic Acid; Lithium Chloride; Male; Mice; Mice, Inbred C57BL; Mice, Knockout

2018
A hypothetical method for controlling highly glycolytic cancers and metastases.
    Medical hypotheses, 2018, Volume: 118

    Topics: Blood Glucose; Cell Proliferation; Cerebrovascular Circulation; Deoxyglucose; Diet, Ketogenic; Glutamine; Glycolysis; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Models, Theoretical; Neoplasm Metastasis; Neoplasms

2018
Co-delivery of 2-Deoxyglucose and a glutamine metabolism inhibitor V9302 via a prodrug micellar formulation for synergistic targeting of metabolism in cancer.
    Acta biomaterialia, 2020, 03-15, Volume: 105

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Drug Liberation; Drug Synergism; Female; Glucose; Glutamine; Humans; Mice, Inbred BALB C; Micelles; Neoplasms; Polyethylene Glycols; Prodrugs; Tissue Distribution

2020
Starvation and antimetabolic therapy promote cytokine release and recruitment of immune cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 05-05, Volume: 117, Issue:18

    Topics: Activating Transcription Factor 4; Antimetabolites; Cell Death; Deoxyglucose; Epithelial Cells; Gene Expression Regulation; Glucose; Glutamine; HeLa Cells; Humans; Inflammation; Interleukin-6; Interleukin-8; Macrophages; Metformin; Neoplasms; NF-kappa B; Promoter Regions, Genetic; Starvation; Stress, Physiological

2020
Nicotinamide-N-methyltransferase is a promising metabolic drug target for primary and metastatic clear cell renal cell carcinoma.
    Clinical and translational medicine, 2022, Volume: 12, Issue:6

    Topics: Carcinoma, Renal Cell; Deoxyglucose; Glucose; Glutamine; Humans; Kidney Neoplasms; Niacinamide; Tumor Microenvironment

2022