glutamine and cholecystokinin

glutamine has been researched along with cholecystokinin in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199070 (78.65)18.7374
1990's17 (19.10)18.2507
2000's1 (1.12)29.6817
2010's0 (0.00)24.3611
2020's1 (1.12)2.80

Authors

AuthorsStudies
Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Storey, E1
Baba, S; Fujii, M; Fujisawa, T; Hasegawa, H; Koide, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S1
Biliotti, D; Bontempo, I; Corazziari, E; De Medici, A; Pallotta, N; Ricci, R; Torsoli, A1
Douglas, BR; Jansen, JB; Lamers, CB; Rovati, LC; Woutersen, RA1
Hashimoto, T; MacLellan, DG; Poston, GJ; Thompson, JC; Townsend, CM; Upp, JR1
Beglinger, C; Gyr, K; Hildebrand, P; Jansen, JB; Lamers, CB; Rovati, LC; Setnikar, I; Stalder, GA; Zuercher, M1
Bonato, C; De Fazio, C; Festorazzi, S; Malesci, A; Rovati, L; Setnikar, I; Tacconi, M; Valentini, A1
Baba, H; Fujimura, M; Toda, N1
Fujii, M; Itoh, H; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S1
Douglas, BR; Jansen, JB; Jebbink, MC; Lamers, CB1
Kellstein, DE; Mayer, DJ1
Liu, Y; Xu, QZ; Zhang, J1
Jansen, JB; Jebbink, MC; Lamers, CB; Masclee, AA1
Gabryelewicz, A; Konturek, SJ; Kulesza, E1
Beauchamp, RD; Gomez, G; Greeley, GH; Nealon, WH; Thompson, JC; Townsend, CM1
Chayvialle, JA; Guillaume, P; Hahne, W; Loizeau, E; Miazza, BM; Turberg, Y1
Grendell, JH; Niederau, C; Rothman, SS1
Johnson, LR; Tabata, K; Yamaguchi, T1
Grendell, JH; Niederau, C; Niederau, M; Williams, JA1
Gardner, JD; Jensen, RT; Jones, SW; Murphy, RB; Rovati, LA; Setnikar, I; Zhou, ZC1
Grendell, JH; Liddle, RA; Niederau, C; Williams, JA1
Dobronyi, I; Papp, M; Scarpignato, C; Varga, G1
Baba, S; Fujii, M; Fujisawa, T; Koide, M; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S3
Chang, JH; Moriyoshi, Y; Shimizu, K; Shiratori, K; Takeuchi, T; Watanabe, S1
Adler, G; Beglinger, C; Dill, S; Meyer, B; Werth, B1
Baba, S; Inui, A; Sakatani, N1
Allescher, HD; Daniel, EE; Fox, JE; Kostolanska, F; Rovati, LA1
Dembinski, A; Jaworek, J; Konturek, PK; Konturek, SJ; Warzecha, Z1
Chisté, R; Giacovelli, G; Rovati, LC; Setnikar, I1
Fujii, K; Kishimoto, M; Miyoshi, A1
Arabatsis, P; Lehmann, KA; Schlüsener, M1
Adler, G; Arnold, R; Göke, B; Koop, I; Reinshagen, M; Rovati, LC; Schafmayer, A1
Matsukura, S; Mitsukawa, T; Nakatsuru, K; Nishizono, F; Ohgo, S; Takemura, J1
Burt, S; Kerwin, JF; Kopecka, H; Lin, CW; Miller, T; Nadzan, AM; Witte, D1
de Jong, AJ; Douglas, BR; Jansen, JB; Lamers, CB; Rovati, LC; Woutersen, RA2
Bogdal, J; Konturek, JW; Konturek, SJ; Kurek, A; Oleksy, J; Rovati, L1
Bunney, BS; Chiodo, LA; Freeman, AS2
Gardiner, J; Grider, JR; Loewe, CJ; Vlahcevic, ZR1
Fukuoka, S; Fushiki, T; Iwai, K; Kondoh, M1
Vaccarino, AL; Vaccarino, FJ1
de Jong, AJ; Jansen, JB; Lamers, CB1
Ammon, HP; Goldfine, ID; Verspohl, EJ; Williams, JA; Wunderle, G1
McCann, SM; Vijayan, E2
Nagy, I; Pap, A; Takács, T; Varró, V1
Konturek, P; Konturek, SJ; Laskiewicz, J; Thor, P1
Ammon, HP; Verspohl, EJ; Wunderle, G1
Funakoshi, A; Kitani, K; Miyasaka, K; Nakamura, R1
Crawley, JN1
Baba, S; Inoue, T; Inui, A; Morioka, H; Oya, M; Sakatani, N1
Cieszkowski, M; Hladij, M; Konturek, SJ; Szewczyk, K; Tasler, J1
Chisté, R; Makovec, F; Rovati, LC; Setnikar, I; Warrington, SJ1
Bani, M; Cereda, R; Chisté, R; Makovec, F; Pacini, MA; Revel, L; Setnikar, I1
Bani, M; Cereda, R; Chisté, R; Makovec, F; Pacini, MA; Revel, L; Rovati, LA; Rovati, LC; Setnikar, I2
Beglinger, C; Gyr, K; Hildebrand, P; Köhler, E; Setnikar, I1
Hansky, J; Smith, GC; Willis, GL1
Kimura, I; Kimura, M; Kondoh, T1
Bani, M; Cereda, R; Chistè, R; Makovec, F; Pacini, MA; Revel, L; Rovati, LC1
Barthó, L; Holzer, P; Lembeck, F; Lippe, IT; Setnikar, I1
Hisamitsu, T; Okada, M1
Pfaus, JG; Phillips, AG1
Bareggi, SR; Bianchi, M; Mantegazza, P; Panerai, AE; Rovati, LC1
Eran, M; Faber, J; Freier, S1
Bunney, BS; Charney, DS; Glazer, WM; Heninger, GR; Innis, RB; Price, LH; Rubin, AL; Sternberg, DE1
Beauchamp, RD; Nealon, WH; Thompson, JC; Townsend, CM1
Davison, JS; Shillabeer, G3
Kinscheck, IB; Mayer, DJ; Watkins, LR1
Miller, J; Price, C; Price, DD; Rafii, A; von der Gruen, A1
Baldy, WJ; Bean, AJ; Martin, GE1
Camus, J; Christophe, J; Deschodt-Lanckman, M; Kutzner, R; Robberecht, P1
Gardner, JD; Hahne, WF; Jensen, RT; Lemp, GF1
Bailey, A; Steigerwalt, RW; Williams, JA1
Akanuma, Y; Iwamoto, Y; Nakamura, R1
Chou, J; Costa, E; Iadarola, M; Tang, J; Yang, HY1
Kaplita, PV; Roebuck, BD1
Beglinger, C; Fried, M; Gyr, K; Koehler, E; Varga, L; Whitehouse, I1
Bunney, BS; Chiodo, LA1
Belbeck, L; Collins, S; Forsyth, P; Walker, D1
Frigerio, S; Giovanetti, R; Letari, O; Makovec, F; Mennuni, L; Peris, W; Revel, L1
Escrieut, C; Fourmy, D; Fréhel, D; Gigoux, V; Gully, D; Kennedy, K; Maigret, B; Martinez, J; Moroder, L; Vaysse, N1
Cui, ZY; Park, HJ; Park, HS; Park, YD; Wu, G1
Bilonoha, OO; Ivasechko, II; Manko, BO; Manko, VV; Voloshyn, DM; Zub, AM1

Trials

4 trial(s) available for glutamine and cholecystokinin

ArticleYear
Oral administration of loxiglumide (CCK antagonist) inhibits postprandial gallbladder contraction without affecting gastric emptying.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:1

    Topics: Administration, Oral; Adult; Cholecystokinin; Double-Blind Method; Female; Food; Gallbladder; Gastric Emptying; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Random Allocation

1990
Lack of effect of the specific cholecystokinin receptor antagonist loxiglumide on cholecystokinin clearance from plasma in man.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:6

    Topics: Adult; Cholecystokinin; Female; Glutamine; Half-Life; Humans; Male; Proglumide

1990
Failure of proglumide, a cholecystokinin antagonist, to potentiate clinical morphine analgesia. A randomized double-blind postoperative study using patient-controlled analgesia (PCA).
    Anesthesia and analgesia, 1989, Volume: 68, Issue:1

    Topics: Adult; Cholecystokinin; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Glutamine; Humans; Male; Middle Aged; Morphine; Pain, Postoperative; Proglumide; Random Allocation; Self Administration

1989
Does the cholecystokinin antagonist proglumide possess antipsychotic activity?
    Psychiatry research, 1986, Volume: 18, Issue:1

    Topics: Adult; Cholecystokinin; Female; Glutamine; Humans; Pilot Projects; Proglumide; Schizophrenia

1986

Other Studies

85 other study(ies) available for glutamine and cholecystokinin

ArticleYear
The cortical lesion of Huntington's disease: further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl-D-aspartate lesions of rat cortex.
    Annals of neurology, 1992, Volume: 32, Issue:4

    Topics: Age Factors; Aged; Animals; Aspartic Acid; Brain Chemistry; Cholecystokinin; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Huntington Disease; Male; Middle Aged; N-Methylaspartate; Neurochemistry; Rats; Rats, Sprague-Dawley; Somatostatin; Substance P

1992
Proglumide analogues CR 1409 and CR 1392 inhibit cholecystokinin-stimulated insulin release more potently than exocrine secretion from the isolated perfused rat pancreas.
    Pancreas, 1990, Volume: 5, Issue:3

    Topics: Animals; Cholecystokinin; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Proglumide; Radioimmunoassay; Rats; Rats, Inbred Strains

1990
Comparison of the effect of lorglumide on pancreatic growth stimulated by camostate in rat and hamster.
    Life sciences, 1990, Volume: 46, Issue:4

    Topics: Animals; Cholecystokinin; Cricetinae; DNA; Esters; Gabexate; Gelatin; Glutamine; Guanidines; Male; Mesocricetus; Organ Size; Pancreas; Proglumide; Proteins; Rats; Rats, Inbred Strains; Stimulation, Chemical; Trypsin Inhibitors

1990
In vivo comparison of inhibition with proglumide and CR-1409 of cholecystokinin-induced pressure in the biliary tract of the guinea pig.
    Surgery, gynecology & obstetrics, 1990, Volume: 170, Issue:3

    Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Gallbladder; Glutamine; Guinea Pigs; Male; Muscle Contraction; Pressure; Proglumide; Time Factors; Transducers

1990
Effects of a cholecystokinin receptor antagonist on intestinal phase of pancreatic and biliary responses in man.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:3

    Topics: Adult; Bile Acids and Salts; Cholecystokinin; Food; Glutamine; Humans; Intestines; Male; Pancreas; Pancreatic Polypeptide; Proglumide; Receptors, Cholecystokinin

1990
Effect of loxiglumide on gallbladder contractile response to cerulein and food in humans.
    Gastroenterology, 1990, Volume: 98, Issue:5 Pt 1

    Topics: Adult; Ceruletide; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Feeding Behavior; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Reference Values; Time Factors

1990
Mechanism of inhibitory action of peptide YY on cholecystokinin-induced contractions of isolated dog ileum.
    Regulatory peptides, 1990, Feb-04, Volume: 27, Issue:2

    Topics: Animals; Cholecystokinin; Dogs; Female; Gallbladder; Glutamine; Ileum; Isometric Contraction; Male; Muscle Contraction; Peptide YY; Peptides; Proglumide; Sincalide

1990
Effect of a new cholecystokinin receptor antagonist loxiglumide on acute pancreatitis in two experimental animal models.
    Pancreas, 1990, Volume: 5, Issue:3

    Topics: Acute Disease; Animals; Ceruletide; Cholecystokinin; Disease Models, Animal; Glutamine; Male; Pancreatitis; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Taurocholic Acid

1990
Effect of loxiglumide (CR-1505) on bombesin- and meal-stimulated plasma cholecystokinin in man.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:4

    Topics: Adult; Bombesin; Cholecystokinin; Female; Food; Glutamine; Humans; Male; Proglumide; Receptors, Cholecystokinin

1990
Chronic administration of cholecystokinin antagonists reverses the enhancement of spinal morphine analgesia induced by acute pretreatment.
    Brain research, 1990, May-21, Volume: 516, Issue:2

    Topics: Analgesia; Animals; Cholecystokinin; Glutamine; Injections, Spinal; Male; Morphine; Proglumide; Rats; Rats, Inbred Strains; Spinal Cord

1990
[Effects of cholecystokinin, gastrin and proglumide on bile secretion in rats].
    Sheng li xue bao : [Acta physiologica Sinica], 1990, Volume: 42, Issue:2

    Topics: Animals; Bile; Cholecystokinin; Female; Glutamine; Male; Pentagastrin; Proglumide; Rats; Rats, Inbred Strains; Secretory Rate

1990
Comparison of loxiglumide, a cholecystokinin receptor antagonist, and atropine on hormonal and meal-stimulated pancreatic secretion in man.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:7

    Topics: Adult; Atropine; Bicarbonates; Cholecystokinin; Duodenum; Eating; Food, Formulated; Glutamine; Humans; Infusions, Intravenous; Pancreas; Proglumide; Receptors, Cholecystokinin; Secretin; Secretory Rate

1990
Proglumide inhibits cholecystokinin and meal-stimulated pancreatic secretion and release of pancreatic polypeptide.
    Surgery, 1990, Volume: 108, Issue:3

    Topics: Amino Acids; Animals; Cholecystokinin; Dogs; Female; Gastrins; Glutamine; Male; Neurotensin; Oleic Acid; Oleic Acids; Pancreas; Pancreatic Polypeptide; Proglumide

1990
Mechanism of pancreatic growth induced by pancreatico-biliary diversion in the rat. Inhibition by proglumide, benzotript, and ranitidine.
    Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 112

    Topics: Adaptation, Physiological; Animals; Benzamides; Biliary Tract; Cholecystokinin; DNA; Gastrins; Glutamine; Male; Organ Size; Pancreas; Pancreatic Polypeptide; Proglumide; Proteins; Ranitidine; Rats; RNA; Secretin

1985
Effects of proglumide on ductal and basolateral secretion of pancreatic digestive enzymes.
    The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 1

    Topics: Amylases; Animals; Cholecystokinin; Chymotrypsinogen; Glutamine; In Vitro Techniques; Male; Methacholine Chloride; Methacholine Compounds; Pancreas; Pancreatic Ducts; Proglumide; Proteins; Rabbits; Regression Analysis

1985
Effect of proglumide on rat pancreatic growth.
    The American journal of physiology, 1985, Volume: 249, Issue:2 Pt 1

    Topics: Animals; Cholecystokinin; DNA; Gastrins; Glutamine; Male; Organ Size; Pancreas; Proglumide; Proteins; Rats; Rats, Inbred Strains; RNA; Sincalide

1985
New proglumide-analogue CCK receptor antagonists: very potent and selective for peripheral tissues.
    The American journal of physiology, 1986, Volume: 250, Issue:6 Pt 1

    Topics: Amylases; Animals; Biological Assay; Cerebral Cortex; Cholecystokinin; Glutamine; Male; Mice; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide

1986
Structural features of various proglumide-related cholecystokinin receptor antagonists.
    The American journal of physiology, 1986, Volume: 251, Issue:6 Pt 1

    Topics: Amylases; Animals; Cholecystokinin; Glutamine; Guinea Pigs; Kinetics; Male; Mice; Pancreas; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide; Structure-Activity Relationship

1986
Pancreatic growth: interaction of exogenous cholecystokinin, a protease inhibitor, and a cholecystokinin receptor antagonist in mice.
    Gut, 1987, Volume: 28 Suppl

    Topics: Amylases; Animals; Cholecystokinin; Chymotrypsinogen; Esters; Gabexate; Glutamine; Guanidines; Male; Mice; Organ Size; Pancreas; Proglumide; Protease Inhibitors; Sincalide

1987
Effect of a new potent CCK antagonist, lorglumide, on caerulein- and bombesin-induced pancreatic secretion and growth in the rat.
    British journal of pharmacology, 1989, Volume: 96, Issue:3

    Topics: Amylases; Anesthesia; Animals; Body Weight; Bombesin; Ceruletide; Cholecystokinin; DNA; Glutamine; In Vitro Techniques; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Trypsin

1989
Loxiglumide. A new proglumide analog with potent cholecystokinin antagonistic activity in the rat pancreas.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:6

    Topics: Amylases; Animals; Binding, Competitive; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; Pancreas; Proglumide; Rats; Receptors, Cholecystokinin; Sincalide

1989
[Inhibitory effect of CR 1409 (cholecystokinin antagonist) on pancreatic exocrine secretion in rats].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1989, Volume: 86, Issue:1

    Topics: Amylases; Animals; Cholecystokinin; Glutamine; Male; Pancreas; Pancreatic Juice; Proglumide; Rats; Rats, Inbred Strains; Sincalide

1989
[Inhibitory effect of a new proglumide derivative, loxiglumide, on CCK action in isolated rat pancreatic acini].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1989, Volume: 86, Issue:1

    Topics: Amylases; Animals; Cholecystokinin; Glutamine; In Vitro Techniques; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Sincalide

1989
Effects of a new proglumide analogue CR 1392 on pancreatic exocrine secretion in the rat.
    Digestion, 1989, Volume: 42, Issue:2

    Topics: Amylases; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide

1989
Treatment of biliary colic with loxiglumide.
    Lancet (London, England), 1989, Jul-15, Volume: 2, Issue:8655

    Topics: Biliary Tract Diseases; Cholecystokinin; Colic; Female; Glutamine; Humans; Male; Proglumide; Time Factors

1989
[The effect of cholecystokinin antagonists on satiety induced by cholecystokinin octapeptide in dogs].
    Nihon Naibunpi Gakkai zasshi, 1989, Oct-20, Volume: 65, Issue:10

    Topics: Animals; Blood-Brain Barrier; Cholecystokinin; Dogs; Eating; Glutamine; Injections, Intravenous; Injections, Intraventricular; Proglumide; Receptors, Cholecystokinin; Sincalide

1989
Effect of the novel cholecystokinin receptor antagonist CR-1392 on cholecystokinin-induced antroduodenal and pyloric motor activity in vivo.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3

    Topics: Animals; Cholecystokinin; Dogs; Duodenum; Electric Stimulation; Female; Gastrointestinal Motility; Glutamine; Male; Proglumide; Pyloric Antrum; Pylorus; Receptors, Cholecystokinin; Tetrodotoxin

1989
Cholecystokinin receptor antagonism by peptidergic and non-peptidergic agents in rat pancreas.
    The Journal of physiology, 1989, Volume: 411

    Topics: Animals; Benzodiazepinones; Bombesin; Ceruletide; Cholecystokinin; Devazepide; DNA; Esters; Gabexate; Glutamine; Guanidines; Pancreas; Pentagastrin; Proglumide; Protease Inhibitors; Proteins; Rats; Receptors, Cholecystokinin

1989
Pharmacokinetics and tolerance of repeated oral doses of loxiglumide.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:11

    Topics: Adult; Biotransformation; Cholecystokinin; Female; Glutamine; Humans; Male; Patient Compliance; Proglumide

1989
[Effect of CCK on the large intestine].
    Nihon Heikatsukin Gakkai zasshi, 1989, Volume: 25, Issue:5

    Topics: Animals; Cholecystokinin; Gastrointestinal Motility; Glutamine; Intestine, Large; Male; Muscle Contraction; Muscle, Smooth; Proglumide; Rats; Rats, Inbred Strains

1989
Differential effects of atropine and a cholecystokinin receptor antagonist on pancreatic secretion.
    Gastroenterology, 1989, Volume: 96, Issue:4

    Topics: Adult; Atropine; Cholecystokinin; Dose-Response Relationship, Drug; Esters; Feedback; Gabexate; Glutamine; Guanidines; Humans; Male; Pancreas; Peptide Hydrolases; Proglumide; Protease Inhibitors; Pulse; Reference Values

1989
Effects of atropine, proglumide, and somatostatin analogue (SMS 201-995) on bombesin-induced gallbladder contraction and CCK secretion in humans.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:11

    Topics: Adult; Atropine; Bombesin; Cholecystokinin; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; Octreotide; Proglumide; Radioimmunoassay; Reference Values; Ultrasonography

1989
Hybrid cholecystokinin (CCK) antagonists: new implications in the design and modification of CCK antagonists.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: Benzodiazepines; Benzodiazepinones; Chemical Phenomena; Chemistry; Cholecystokinin; Devazepide; Drug Design; Glutamine; Molecular Conformation; Proglumide; Receptors, Cholecystokinin; Stereoisomerism; Structure-Activity Relationship

1989
Modulation by CR-1409 (lorglumide), a cholecystokinin receptor antagonist, of trypsin inhibitor-enhanced growth of azaserine-induced putative preneoplastic lesions in rat pancreas.
    Cancer research, 1989, May-01, Volume: 49, Issue:9

    Topics: Animals; Azaserine; Cholecystokinin; Esters; Gabexate; Glutamine; Guanidines; Male; Pancreatic Neoplasms; Precancerous Conditions; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide; Trypsin Inhibitors

1989
CCK receptor antagonism by loxiglumide and gall bladder contractions in response to cholecystokinin, sham feeding and ordinary feeding in man.
    Gut, 1989, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Cholecystokinin; Food; Gallbladder; Glutamine; Humans; Male; Muscle Contraction; Proglumide; Receptors, Cholecystokinin; Sincalide

1989
Further studies on the specificity of proglumide as a selective cholecystokinin antagonist in the central nervous system.
    Annals of the New York Academy of Sciences, 1985, Volume: 448

    Topics: Animals; Anorexia Nervosa; Antipsychotic Agents; Apomorphine; Brain; Cholecystokinin; Glutamine; Humans; Mesencephalon; Neurons; Proglumide; Receptors, Dopamine; Schizophrenia

1985
Selective inhibition of pentagastrin- and cholecystokinin-stimulated exocrine secretion by proglumide.
    Gastroenterology, 1985, Volume: 89, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cholecystokinin; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Glutamine; Histamine; Male; Pancreas; Pentagastrin; Proglumide; Rats; Secretin

1985
Influence of neural blockages and proglumide on rat pancreatic enzyme secretion in response to intraluminal fatty acid.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 186, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nerve Block; Cholecystokinin; Drug Interactions; Glutamine; Hexamethonium; Hexamethonium Compounds; Male; Oleic Acid; Oleic Acids; Pancreas; Pancreatic Juice; Parasympatholytics; Proglumide; Rats; Rats, Inbred Strains; Secretory Rate; Trypsin

1987
Influence of cholecystokinin antagonist on the effects of cholecystokinin and bombesin on azaserine-induced lesions in rat pancreas.
    Gastroenterology, 1989, Volume: 96, Issue:2 Pt 1

    Topics: Animals; Azaserine; Bombesin; Cholecystokinin; Glutamine; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains

1989
Antagonism of cholecystokinin function in the rostral and caudal nucleus accumbens: differential effects on brain stimulation reward.
    Neuroscience letters, 1989, Feb-13, Volume: 97, Issue:1-2

    Topics: Animals; Brain; Cholecystokinin; Glutamine; Male; Nucleus Accumbens; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Reward; Septal Nuclei

1989
The cholecystokinin receptor antagonist CR1409 increases plasma cholecystokinin in rats.
    Regulatory peptides, 1989, Volume: 24, Issue:2

    Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; Male; Proglumide; Rats; Rats, Inbred Strains

1989
Proglumide (gastrin and cholecystokinin receptor antagonist) inhibits insulin secretion in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:3

    Topics: Animals; Cholecystokinin; Culture Techniques; Depression, Chemical; Female; Gastric Inhibitory Polypeptide; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Male; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholecystokinin; Sincalide

1986
Electrophysiological studies on the specificity of the cholecystokinin antagonist proglumide.
    Brain research, 1987, May-05, Volume: 410, Issue:2

    Topics: Action Potentials; Animals; Apomorphine; Brain; Cerebral Cortex; Cholecystokinin; Dopamine; Enkephalin, Methionine; gamma-Aminobutyric Acid; Glutamine; Male; Neurotensin; Proglumide; Rats; Receptors, Neurotransmitter; Sodium Glutamate; Substantia Nigra

1987
The effects of the cholecystokinin antagonist, proglumide, on gonadotropin release in the rat.
    Brain research bulletin, 1986, Volume: 16, Issue:4

    Topics: Animals; Castration; Cholecystokinin; Female; Follicle Stimulating Hormone; Glutamine; Gonadotropins, Pituitary; Injections, Intravenous; Injections, Intraventricular; Luteinizing Hormone; Male; Proglumide; Rats; Rats, Inbred Strains

1986
The anti-CCK effect of glutaramic acid derivatives in anesthetized and conscious rats.
    Pancreas, 1988, Volume: 3, Issue:4

    Topics: Anesthesia; Animals; Cholecystokinin; Glutamine; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains

1988
Cholecystokinin in the regulation of intestinal motility and pancreatic secretion in dogs.
    The American journal of physiology, 1988, Volume: 255, Issue:4 Pt 1

    Topics: Animals; Benzodiazepinones; Bethanechol Compounds; Bicarbonates; Bombesin; Cholecystokinin; Devazepide; Dogs; Eating; Gastrins; Gastrointestinal Motility; Glutamine; Pancreatic Juice; Proglumide; Proteins; Reference Values

1988
Proglumide antagonizes cholecystokinin effects on plasma glucose and insulin in rats in vivo.
    European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2

    Topics: Animals; Blood Glucose; Cholecystokinin; Esters; Female; Gabexate; Glucose Tolerance Test; Glutamine; Guanidines; Insulin Antagonists; Male; Proglumide; Protease Inhibitors; Rats; Rats, Inbred Strains

1988
Inhibitory effect of CR-1409, a competitive inhibitor of cholecystokinin, on pancreatic exocrine secretion in the conscious rat.
    The Tohoku journal of experimental medicine, 1988, Volume: 155, Issue:2

    Topics: Animals; Bicarbonates; Cholecystokinin; Dose-Response Relationship, Drug; Female; Glutamine; Male; Pancreatic Juice; Proglumide; Proteins; Rats; Rats, Inbred Strains; Reference Values; Sincalide

1988
Attenuation of dark-induced hyperlocomotion by a cholecystokinin antagonist in the nucleus accumbens.
    Brain research, 1988, Nov-15, Volume: 473, Issue:2

    Topics: Animals; Cholecystokinin; Darkness; Exploratory Behavior; Glutamine; Light; Male; Motor Activity; Nucleus Accumbens; Proglumide; Rats; Rats, Inbred Strains; Reference Values; Septal Nuclei

1988
Comparison of effects of proglumide and CR 1409, a new glutaramic acid derivative, on CCK-8-induced pancreatic polypeptide and insulin secretion in the dog.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1988, Volume: 20, Issue:1

    Topics: Animals; Cholecystokinin; Dogs; Glutamine; Insulin; Insulin Secretion; Pancreatic Polypeptide; Proglumide

1988
Effect of cholecystokinin receptor antagonist on pancreatic responses to exogenous gastrin and cholecystokinin and to meal stimuli.
    Gastroenterology, 1988, Volume: 94, Issue:4

    Topics: Animals; Cholecystokinin; Dogs; Food; Gastric Fistula; Gastrins; Glutamine; Pancreas; Pancreatic Fistula; Pancreatic Polypeptide; Proglumide; Receptors, Cholecystokinin

1988
Pharmacokinetics of loxiglumide after single intravenous or oral doses in man.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:5

    Topics: Administration, Oral; Adult; Cholecystokinin; Chromatography, High Pressure Liquid; Glutamine; Humans; Infusions, Intravenous; Injections, Intravenous; Proglumide

1988
Anticholecystokinin activities of loxiglumide.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:10

    Topics: Anesthesia; Animals; Ceruletide; Cholecystokinin; Dogs; Female; Gallbladder; Gastrointestinal Motility; Glutamine; Guinea Pigs; In Vitro Techniques; Male; Mice; Pancreas; Proglumide; Rabbits; Rats; Rats, Inbred Strains; Species Specificity

1987
Pharmacological properties of lorglumide as a member of a new class of cholecystokinin antagonists.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:11

    Topics: Animals; Cholecystokinin; Dogs; Gallbladder; Glutamine; Guinea Pigs; Ileum; In Vitro Techniques; Mice; Muscle Contraction; Pancreas; Proglumide; Rats; Receptors, Cholecystokinin

1987
Biological effects of a proglumide derivative as cholecystokinin antagonist in conscious dogs.
    Regulatory peptides, 1987, Aug-17, Volume: 18, Issue:3-4

    Topics: Animals; Cholecystokinin; Dogs; Dose-Response Relationship, Drug; Gastric Acid; Glutamine; Infusions, Intravenous; Pancreatic Juice; Pancreatic Polypeptide; Pentagastrin; Proglumide; Sincalide

1987
Central and peripheral proglumide administration and cholecystokinin-induced satiety.
    Regulatory peptides, 1986, Volume: 15, Issue:1

    Topics: Animals; Catheterization; Cerebral Ventricles; Cholecystokinin; Drinking Behavior; Feeding Behavior; Glutamine; Hypothalamus; Injections, Intraperitoneal; Male; Organ Specificity; Proglumide; Rats; Rats, Inbred Strains; Satiation; Stereotaxic Techniques

1986
Proglumide peptides and CCK antagonistic action in hog duodenal circular muscle.
    European journal of pharmacology, 1987, Feb-10, Volume: 134, Issue:2

    Topics: Animals; Cholecystokinin; Duodenum; Female; Glutamine; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Peptide Fragments; Proglumide; Receptors, Cholecystokinin; Structure-Activity Relationship; Swine

1987
Antispasmodic activity on the gallbladder of the mouse of CR 1409 (lorglumide) a potent antagonist of peripheral CCK.
    Pharmacological research communications, 1987, Volume: 19, Issue:1

    Topics: Animals; Atropine; Cholecystokinin; Dose-Response Relationship, Drug; Female; Gallbladder; Glutamine; Mice; Mice, Inbred Strains; Nifedipine; Papaverine; Parasympatholytics; Proglumide

1987
Evaluation of a new and potent cholecystokinin antagonist on motor responses of the guinea-pig intestine.
    British journal of pharmacology, 1987, Volume: 90, Issue:4

    Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Electric Stimulation; Female; Glutamine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Proglumide; Receptors, Cholecystokinin; Reflex

1987
[Cholecystokinin antagonist (proglumide) potentiates the inhibitory effect of morphine on micturition reflex].
    Masui. The Japanese journal of anesthesiology, 1987, Volume: 36, Issue:6

    Topics: Animals; Cholecystokinin; Depression, Chemical; Drug Synergism; Female; Glutamine; Morphine; Proglumide; Rats; Rats, Inbred Strains; Reflex; Urination

1987
Pharmacological characterisation of a new potent and specific nonpolypeptidic cholecystokinin antagonist.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:6

    Topics: Animals; Cerebral Cortex; Cholecystokinin; Female; Gallbladder; Glutamine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle, Smooth; Pancreas; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Species Specificity

1987
Cholecystokinin facilitates ejaculation in male rats: blockade with proglumide and apomorphine.
    European journal of pharmacology, 1987, Sep-23, Volume: 141, Issue:3

    Topics: Animals; Apomorphine; Cholecystokinin; Copulation; Dose-Response Relationship, Drug; Ejaculation; Glutamine; Male; Proglumide; Rats; Sexual Behavior, Animal

1987
Effect of a cholecystokinin antagonist on some effects of diazepam.
    Neuropharmacology, 1987, Volume: 26, Issue:9

    Topics: Animals; Cholecystokinin; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Glutamine; Male; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Proglumide; Seizures

1987
Effect of cholecystokinin and of its antagonist, of atropine, and of food on the release of immunoglobulin A and immunoglobulin G specific antibodies in the rat intestine.
    Gastroenterology, 1987, Volume: 93, Issue:6

    Topics: Animals; Antibody Specificity; Atropine; Cholecystokinin; Food, Formulated; Glutamine; Immunoglobulin A; Immunoglobulin G; Intestinal Mucosa; Proglumide; Rats

1987
Role of cholecystokinin in canine pancreatic exocrine response to bombesin stimulation.
    American journal of surgery, 1987, Volume: 153, Issue:1

    Topics: Animals; Bombesin; Cholecystokinin; Dogs; Drug Interactions; Glutamine; Infusions, Intravenous; Pancreas; Proglumide

1987
The effects of the cholecystokinin antagonist, proglumide, on prolactin secretion in the rat.
    Life sciences, 1987, Feb-16, Volume: 40, Issue:7

    Topics: Animals; Cholecystokinin; Female; Glutamine; Injections, Intravenous; Injections, Intraventricular; Male; Proglumide; Prolactin; Rats; Rats, Inbred Strains

1987
Proglumide, a cholecystokinin antagonist, increases gastric emptying in rats.
    The American journal of physiology, 1987, Volume: 252, Issue:2 Pt 2

    Topics: Administration, Oral; Animals; Cholecystokinin; Eating; Gastric Acid; Gastric Emptying; Glutamine; Injections, Intraperitoneal; Injections, Intravenous; Male; Mathematics; Proglumide; Rats; Rats, Inbred Strains; Time Factors

1987
Potentiation of morphine analgesia by the cholecystokinin antagonist proglumide.
    Brain research, 1985, Feb-18, Volume: 327, Issue:1-2

    Topics: Analgesia; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Drug Synergism; Glutamine; Injections, Spinal; Male; Microinjections; Morphine; Pain; Periaqueductal Gray; Proglumide; Rats; Rats, Inbred Strains; Reaction Time; Time Factors

1985
Potentiation of systemic morphine analgesia in humans by proglumide, a cholecystokinin antagonist.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:8

    Topics: Adult; Cholecystokinin; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Glutamine; Humans; Injections, Intravenous; Morphine; Pain; Proglumide; Random Allocation

1985
The effect of vagotomy on the increase in food intake induced by the cholecystokinin antagonist, proglumide.
    Regulatory peptides, 1985, Volume: 12, Issue:2

    Topics: Animals; Appetite; Body Weight; Cholecystokinin; Energy Intake; Glutamine; Male; Proglumide; Rats; Rats, Inbred Strains; Vagotomy

1985
Chronic proglumide increases [3H]spiperone binding in the rat brain.
    European journal of pharmacology, 1985, Oct-29, Volume: 117, Issue:1

    Topics: Animals; Brain Chemistry; Butyrophenones; Cholecystokinin; Corpus Striatum; Glutamine; In Vitro Techniques; Kinetics; Male; Proglumide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone

1985
Amino acid levels in rat pancreas after pilocarpine or pancreozymin.
    The American journal of physiology, 1973, Volume: 224, Issue:6

    Topics: Alanine; Amino Acids; Amylases; Animals; Aspartic Acid; Cholecystokinin; Chymotrypsinogen; Female; Glutamates; Glutamine; Injections, Intraperitoneal; Injections, Intravenous; Intestine, Small; Lipase; Liver; Oxidative Phosphorylation; Pancreas; Pilocarpine; Rats; Secretory Rate

1973
Proglumide and benzotript: members of a different class of cholecystokinin receptor antagonists.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:10

    Topics: Amylases; Animals; Benzamides; Carbachol; Cholecystokinin; Dibutyryl Cyclic GMP; Glutamine; Guinea Pigs; Kinetics; Male; Pancreas; Proglumide; Receptors, Cell Surface; Receptors, Cholecystokinin

1981
Effects of proglumide on pancreatic acinar cell function.
    Digestion, 1983, Volume: 27, Issue:4

    Topics: Amylases; Animals; Cholecystokinin; Deoxyglucose; Glutamine; Islets of Langerhans; Male; Mice; Proglumide; Receptor, Insulin; Receptors, Cell Surface; Receptors, Cholecystokinin

1983
In vitro and in vivo effect of proglumide on cholecystokinin-stimulated amylase release in mouse pancreatic acini.
    Gastroenterologia Japonica, 1984, Volume: 19, Issue:1

    Topics: Amylases; Animals; Cholecystokinin; Dose-Response Relationship, Drug; Glutamine; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Pancreas; Proglumide; Sincalide; Tetragastrin

1984
Proglumide prevents and curtails acute tolerance to morphine in rats.
    Neuropharmacology, 1984, Volume: 23, Issue:6

    Topics: Animals; Cholecystokinin; Drug Tolerance; Glutamine; Male; Morphine; Proglumide; Rats; Rats, Inbred Strains

1984
The cholecystokinin antagonist, proglumide, increases food intake in the rat.
    Regulatory peptides, 1984, Volume: 8, Issue:3

    Topics: Animals; Appetite; Cholecystokinin; Energy Intake; Fasting; Glutamine; Hunger; Male; Proglumide; Rats; Rats, Inbred Strains

1984
Proglumide antagonizes the stimulation of rabbit gallbladder by cholecystokinin.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 269, Issue:2

    Topics: Acetylcholine; Animals; Cholecystokinin; Female; Gallbladder; Glutamine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Proglumide; Rabbits; Serotonin

1984
Effect of proglumide, a cholecystokinin receptor antagonist, on caerulein-stimulated pancreatic enzyme secretion and pancreatic polypeptide release in the dog.
    Regulatory peptides, 1984, Volume: 8, Issue:2

    Topics: Animals; Ceruletide; Cholecystokinin; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Glutamine; Pancreas; Pancreatic Juice; Pancreatic Polypeptide; Proglumide

1984
Proglumide: selective antagonism of excitatory effects of cholecystokinin in central nervous system.
    Science (New York, N.Y.), 1983, Mar-25, Volume: 219, Issue:4591

    Topics: Animals; Brain; Cerebral Cortex; Cholecystokinin; Drug Antagonism; Glutamine; Male; Mesencephalon; Neurons; Proglumide; Rats

1983
The effects of proglumide on cholecystokinin-, bombesin-, and glucagon-induced satiety in the rat.
    Life sciences, 1983, May-09, Volume: 32, Issue:19

    Topics: Animals; Appetite; Bombesin; Cholecystokinin; Dose-Response Relationship, Drug; Food Deprivation; Glucagon; Glutamine; Male; Peptides; Proglumide; Rats; Rats, Inbred Strains; Time Factors

1983
Structure-antigastrin activity relationships of new spiroglumide amido acid derivatives.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Binding, Competitive; Brain; Cholecystokinin; Computer-Aided Design; Drug Design; Gastric Mucosa; Gastrins; Glutamine; Guinea Pigs; Molecular Conformation; Molecular Structure; Pancreas; Pentagastrin; Piperidines; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Spiro Compounds; Stomach; Structure-Activity Relationship

1996
Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin.
    The Journal of biological chemistry, 1997, Jan-31, Volume: 272, Issue:5

    Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Cholecystokinin; Computer Simulation; COS Cells; Glutamine; Hormone Antagonists; Humans; Kinetics; Ligands; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Recombinant Fusion Proteins; Sincalide; Transfection; Tryptophan

1997
Gamma-aminobutyric acid secreted from islet beta-cells modulates exocrine secretion in rat pancreas.
    World journal of gastroenterology, 2006, May-21, Volume: 12, Issue:19

    Topics: Animals; Bicuculline; Cholecystokinin; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamine; Insulin-Secreting Cells; Male; Pancreas, Exocrine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2006
Pyruvate and Glutamine Define the Effects of Cholecystokinin and Ethanol on Mitochondrial Oxidation, Necrosis, and Morphology of Rat Pancreatic Acini.
    Pancreas, 2021, 08-01, Volume: 50, Issue:7

    Topics: Acinar Cells; Amylases; Animals; Cell Survival; Cells, Cultured; Cholecystokinin; Ethanol; Glutamine; Male; Membrane Potential, Mitochondrial; Microscopy, Fluorescence; Mitochondria; Necrosis; Oxidation-Reduction; Oxygen Consumption; Pancreas; Pyruvic Acid; Rats, Wistar

2021