Compounds > glutamine

glutamine and cb-839

glutamine has been researched along with cb-839 in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's19 (63.33)24.3611
2020's11 (36.67)2.80

Authors

AuthorsStudies
Birsen, R; Bouscary, D; Chapuis, N; Decroocq, J; Demo, S; Hospital, MA; Jacque, N; Joseph, L; Lacombe, C; Lambert, M; Larrue, C; Maciel, TT; Mayeux, P; Meunier, G; Moura, IC; Poulain, L; Recher, C; Ronchetti, AM; Saland, E; Sarry, JE; Sujobert, P; Tamburini, J; Willems, L1
Chen, G; Guo, E; Guo, L; Liu, Z; Lu, H; Shan, W; Wang, C; Xia, M; Xu, Y; Zhou, B1
Alt, J; Chen, B; Elgogary, A; Fu, J; Hanes, J; Hartung, T; Le, A; Lee, R; Liu, Y; Neisser, M; Nguyen, C; Park, JK; Poore, B; Rais, R; Reyes, J; Rojas, C; Semenza, GL; Slusher, BS; Tsukamoto, T; Xia, S; Xu, Q; Zhao, L; Zimmermann, SC1
Baran, N; Cai, T; Chan, SM; Davis, RE; DiNardo, C; Flores, ER; Gonzalez, D; Haferlach, T; Jacamo, R; Konoplev, S; Konopleva, M; Li, W; Lodi, A; Ma, H; Majeti, R; Matre, P; Qi, Y; Samudio, I; Schimmer, AD; Su, X; Sweeney, SR; Tiziani, S; Velez, J; Wang, T1
Bailey, ST; Braas, D; Christofk, HR; Czernin, J; Demo, S; Dubinett, SM; Emberley, E; Fishbein, MC; Garon, E; Graeber, T; Gross, M; Jackson, NJ; Janes, J; Krysan, K; Lee, JT; Mackinnon, A; Magyar, C; Momcilovic, M; Pan, A; Parlati, F; Rodriguez, M; Sadeghi, S; Shackelford, DB; Walser, TC; Works, M; Zhang, W1
D'Alessandro, A; DeGregori, J; Gregory, MA; Hansen, KC; Nemkov, T; Reisz, JA; Zaberezhnyy, V1
Banerjee, S; Barnes, S; Cui, H; Dubey, S; Ge, J; Guo, S; Liu, G; Xie, N1
Abu Aboud, O; Chaudhari, AJ; Habib, SL; Liang, S; Stewart, B; Sutcliffe, J; Trott, J; Weiss, RH1
Bhattacharya, PK; Dutta, P; Jones, LW; Lee, J; Lee, Y; McCullough, C; McHenry, J; Nguyen, L; Norton, W; Shanmugavelandy, S; Zacharias, NM1
Cerione, RA; Huang, Q; Iyer, P; Katt, WP; McDermott, LA; O'Neill, J; Reimer, S; Stalnecker, C; Zhang, C1
Diggs, L; Hatzivassiliou, G; Kimmelman, AC; Li, Z; Parker, SJ; Rais, R; Skolnik, EY; Slusher, BS; Somlo, S; Soomro, I; Sun, Y; Thomas, AG1
Braun, AL; Huang, Y; Li, Y; Liu, J; Peer, J; Tong, Z; Wang, Y; Wu, B; Zhao, L; Zhao, R; Zheng, JC1
Addie, RD; Bovée, JVMG; Cleton-Jansen, AM; Cleven, AHG; de Jong, Y; Kruisselbrink, AB; Molenaar, RJ; Niessen, B; Peterse, EFP; van den Akker, BEWM1
Badran, K; Bailey, ST; Bernthal, NM; Braas, D; Christofk, HR; Demo, S; Dubinett, SM; Federman, N; Fishbein, MC; Fridman, D; Go, J; Graeber, TG; Gricowski, M; Ibarra, J; Lee, JT; Li, R; Momcilovic, M; Parlati, F; Phelps, ME; Sadeghi, S; Shackelford, DB; Shuman, R; St John, M; Walser, TC; Yanagawa, J1
Boysen, G; Davis, MA; Dings, RPM; Griffin, RJ; Jamshidi-Parsian, A; Kore, RA; Siegel, ER; Simecka, CM1
Bass, AJ; Beeson, CC; Beeson, GC; Diehl, JA; Ogretmen, B; Oleinik, N; Parnham, S; Qie, S; Rustgi, AK; Wong, KK; Yoshida, A1
Adamoski, D; Consonni, SR; Corrêa-da-Silva, F; Dias, SMG; Malta de Sá Patroni, F; Meira Dias, M; Mendes de Moraes-Vieira, PM; Ornitz Oliveira Souza, R; Reis, LMD; Rodrigues Ascenção, CF; Silber, AM; Sousa de Oliveira, KR1
Binici, A; Brand, S; Ceballos, J; Choidas, A; Karageorgis, G; Knauer, L; Nowacki, J; Reckzeh, ES; Schwalfenberg, M; Stroet, MCM; Strohmann, C; Waldmann, H; Ziegler, S1
Hong, SE; Hong, YJ; Jang, SK; Jin, HO; Kim, H; Kim, JY; Kim, YS; Lee, JK; Oh, AC; Park, IC; Sim, JH1
Cerione, RA; Erickson, JW; Li, Y; Nguyen, TT; Ramachandran, S; Stalnecker, CA1
Burrows, M; Finan, JM; Gade, TPF; Gong, YY; Huangyang, P; Khare, S; Lee, P; Malik, D; Nissim, I; Perkons, N; Rhoades, S; Simon, MC; Weljie, AM1
Baguley, BC; Dechaume, AL; Katt, WP; Leung, EY; Murray, PM; Singleton, DC1
Asaka, R; Asaka, S; Attarwala, N; Chen, X; Chen, YW; Chuang, CM; Davidson, B; DeMarzo, AM; Gaillard, S; Hong, J; Hsu, FC; Jung, JG; Le, A; Shen, YA; Shih, IM; Suryo Rahmanto, Y; Tomaszewski, A; Wang, TL; Yen, TT; Zhang, C1
Bajor, DL; Chen, Y; Selfridge, JE; Wang, Z; Zhao, Y1
Beijersbergen, R; Berkers, CR; Bernards, R; Bosma, A; Isima, N; Jin, G; Jin, H; Jochems, F; Lieftink, C; Qin, W; Wang, C; Wang, S; Wu, H; Zaal, EA1
Janowitz, T; Lukey, MJ; Qiu, Y; Stamatatos, O; Yang, WH1
Chen, J; Dang, R; Emberley, E; Gross, M; Huang, T; Li, W; MacKinnon, A; Pan, A; Parlati, F; Singh, D; Sotirovska, N; Steggerda, SM; Wang, T1
Baek, GH; Choi, YJ; Jeon, JS; Kang, KW; Kim, S; Kim, SK1
Adhikary, G; Chen, X; Eckert, RL; Emadi, A; Friedberg, JS; Naselsky, W; Newland, JJ; Shrestha, S; Xu, W1
Bader, JE; Chi, C; Fisher, EL; Hathaway, ES; Karijolich, J; Landis, MD; Madden, MZ; Muka, JE; Needle, GA; O'Neil, RT; Patterson, AR; Philip, M; Rathmell, JC; Reinfeld, BI; Wolf, MM; Ye, X1

Reviews

1 review(s) available for glutamine and cb-839

ArticleYear
Enhancing the Efficacy of Glutamine Metabolism Inhibitors in Cancer Therapy.
    Trends in cancer, 2021, Volume: 7, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Clinical Trials as Topic; Disease Models, Animal; Drug Resistance, Neoplasm; Glutaminase; Glutamine; Humans; Neoplasms; NF-E2-Related Factor 2; Oxidative Stress; Thiadiazoles; Tumor Escape; Tumor Microenvironment

2021

Other Studies

29 other study(ies) available for glutamine and cb-839

ArticleYear
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
    Blood, 2015, Sep-10, Volume: 126, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzeneacetamides; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Enzyme Inhibitors; Gene Knockdown Techniques; Glutaminase; Glutamine; Humans; Leukemia, Myeloid, Acute; Mice; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Thiadiazoles; Xenograft Model Antitumor Assays

2015
Blockage of glutaminolysis enhances the sensitivity of ovarian cancer cells to PI3K/mTOR inhibition involvement of STAT3 signaling.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Benzeneacetamides; Blotting, Western; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Flow Cytometry; Gene Knockdown Techniques; Glutaminase; Glutamine; Humans; Indoles; Ovarian Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Purines; Real-Time Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Thiadiazoles; TOR Serine-Threonine Kinases

2016
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2016, 09-06, Volume: 113, Issue:36

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Cell Line, Tumor; Glutaminase; Glutamine; Humans; Metformin; Mice; Nanoparticles; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Sulfides; Thiadiazoles; Xenograft Model Antitumor Assays

2016
Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
    Oncotarget, 2016, Nov-29, Volume: 7, Issue:48

    Topics: Antineoplastic Agents; Apoptosis; Benzeneacetamides; Cell Differentiation; Cell Proliferation; Energy Metabolism; Enzyme Inhibitors; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Mutation; Protein Isoforms; Sulfides; Thiadiazoles

2016
Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer.
    Cell reports, 2017, 01-17, Volume: 18, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Benzeneacetamides; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; ErbB Receptors; Erlotinib Hydrochloride; Fluorodeoxyglucose F18; Glutaminase; Glutamine; Humans; Lung Neoplasms; Mice; Mice, SCID; Mutation; Radiopharmaceuticals; RNA Interference; Thiadiazoles; Transplantation, Heterologous

2017
Glutaminase inhibition improves FLT3 inhibitor therapy for acute myeloid leukemia.
    Experimental hematology, 2018, Volume: 58

    Topics: Animals; Benzeneacetamides; Benzothiazoles; Cell Line, Tumor; Female; fms-Like Tyrosine Kinase 3; Glutamic Acid; Glutaminase; Glutamine; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, Transgenic; Phenylurea Compounds; Thiadiazoles; Xenograft Model Antitumor Assays

2018
Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.
    American journal of respiratory cell and molecular biology, 2018, Volume: 58, Issue:3

    Topics: Actins; Animals; Benzeneacetamides; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Enzyme Activation; Fibronectins; Glutaminase; Glutamine; Humans; Hydroxylation; Ketoglutaric Acids; Mice; Mice, Inbred C57BL; Myofibroblasts; Proline; Pulmonary Fibrosis; RNA Interference; RNA, Small Interfering; Sulfides; Thiadiazoles; TOR Serine-Threonine Kinases

2018
Glutamine Addiction in Kidney Cancer Suppresses Oxidative Stress and Can Be Exploited for Real-Time Imaging.
    Cancer research, 2017, 12-01, Volume: 77, Issue:23

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Benzeneacetamides; Carcinoma, Renal Cell; Deoxyguanosine; Glutaminase; Glutamine; Humans; Kidney Neoplasms; Mice; NF-E2 Transcription Factor; Oxidative Stress; Reactive Oxygen Species; Thiadiazoles; Xenograft Model Antitumor Assays

2017
Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer.
    Scientific reports, 2017, 11-23, Volume: 7, Issue:1

    Topics: Benzeneacetamides; Cell Line, Tumor; Glutaminase; Glutamine; Humans; Male; Nuclear Magnetic Resonance, Biomolecular; Prostatic Neoplasms; Thiadiazoles

2017
Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism.
    The Journal of biological chemistry, 2018, 03-09, Volume: 293, Issue:10

    Topics: Allosteric Site; Amino Acid Substitution; Antineoplastic Agents; Benzeneacetamides; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glutaminase; Glutamine; Humans; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Mutation; Neoplasm Proteins; Recombinant Proteins; Sulfides; Thiadiazoles; Triple Negative Breast Neoplasms

2018
Glutamine metabolism via glutaminase 1 in autosomal-dominant polycystic kidney disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018, 08-01, Volume: 33, Issue:8

    Topics: Animals; Aquaporin 2; Benzeneacetamides; Cell Proliferation; Cells, Cultured; Female; Glutaminase; Glutamine; Humans; Male; Mice; Mice, Knockout; Polycystic Kidney, Autosomal Dominant; Receptors, Cell Surface; Signal Transduction; Thiadiazoles

2018
Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate.
    Journal of neuroinflammation, 2018, Mar-14, Volume: 15, Issue:1

    Topics: Aniline Compounds; Benzeneacetamides; Benzylidene Compounds; Brain; Calcium-Binding Proteins; Cell Cycle Proteins; Cells, Cultured; Central Nervous System; Ceramides; Dose-Response Relationship, Drug; Endosomal Sorting Complexes Required for Transport; Enzyme Inhibitors; Extracellular Vesicles; Glutamates; Glutaminase; Glutamine; HIV Infections; Humans; Lipopolysaccharides; Macrophages; Membrane Proteins; Microglia; Sulfides; Thiadiazoles

2018
Targeting glutaminolysis in chondrosarcoma in context of the IDH1/2 mutation.
    British journal of cancer, 2018, Volume: 118, Issue:8

    Topics: Antineoplastic Agents; Benzeneacetamides; Bone Neoplasms; Chloroquine; Chondrosarcoma; Drug Screening Assays, Antitumor; Glutaminase; Glutamine; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Metabolic Networks and Pathways; Metformin; Molecular Targeted Therapy; Mutation; Neoplasm Grading; Thiadiazoles; Tumor Cells, Cultured

2018
The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.
    Cancer cell, 2018, 05-14, Volume: 33, Issue:5

    Topics: Animals; Benzeneacetamides; Boron Compounds; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glutamine; Glycine; Glycogen Synthase Kinase 3; Glycolysis; Humans; Ki-67 Antigen; Lung Neoplasms; Mice; Neoplasm Transplantation; Signal Transduction; Thiadiazoles

2018
Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice.
    International journal of radiation biology, 2019, Volume: 95, Issue:4

    Topics: Animals; Benzeneacetamides; Cell Line, Tumor; Female; Glutaminase; Glutamine; Glutathione; Humans; Lung Neoplasms; Male; Mice; Radiation Tolerance; Thiadiazoles; Xenograft Model Antitumor Assays

2019
Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma.
    Nature communications, 2019, 03-21, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzeneacetamides; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Drug Resistance, Neoplasm; Drug Synergism; Energy Metabolism; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; F-Box Proteins; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Humans; Hypoglycemic Agents; Male; Mechanistic Target of Rapamycin Complex 1; Metformin; Mice; Molecular Targeted Therapy; Phenformin; Protein Kinase Inhibitors; Retinoblastoma Protein; Signal Transduction; Thiadiazoles; Xenograft Model Antitumor Assays

2019
Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition-resistant triple-negative breast cancer cells.
    The Journal of biological chemistry, 2019, 06-14, Volume: 294, Issue:24

    Topics: Benzeneacetamides; Carnitine O-Palmitoyltransferase; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Female; Glutaminase; Glutamine; Humans; Oxidation-Reduction; Thiadiazoles; Triple Negative Breast Neoplasms; Tumor Cells, Cultured

2019
Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth.
    Cell chemical biology, 2019, 09-19, Volume: 26, Issue:9

    Topics: Benzeneacetamides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; Female; Glucose; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Glutaminase; Glutamine; Glycolysis; Humans; Male; Neoplasms; Thiadiazoles

2019
Knock-down of PSAT1 Enhances Sensitivity of NSCLC Cells to Glutamine-limiting Conditions.
    Anticancer research, 2019, Volume: 39, Issue:12

    Topics: Activating Transcription Factor 4; Benzeneacetamides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Gene Knock-In Techniques; Glutaminase; Glutamine; Humans; Lung; Lung Neoplasms; Radiation Tolerance; RNA, Messenger; Thiadiazoles; Transaminases

2019
The activation loop and substrate-binding cleft of glutaminase C are allosterically coupled.
    The Journal of biological chemistry, 2020, 01-31, Volume: 295, Issue:5

    Topics: Allosteric Regulation; Allosteric Site; Amino Acid Substitution; Animals; Benzeneacetamides; Biomedical Engineering; Catalytic Domain; Glutaminase; Glutamine; Kinetics; Mice; Mitochondria; Models, Molecular; Mutation; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Sulfides; Thiadiazoles

2020
Targeting glutamine metabolism slows soft tissue sarcoma growth.
    Nature communications, 2020, 01-24, Volume: 11, Issue:1

    Topics: Allografts; Animals; Benzeneacetamides; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Glutaminase; Glutamine; Mice; Nucleosides; RNA, Messenger; Sarcoma; Thiadiazoles; Tomography, X-Ray Computed

2020
Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer.
    BMC cancer, 2020, May-25, Volume: 20, Issue:1

    Topics: Benzeneacetamides; Cell Proliferation; Drug Resistance, Neoplasm; Female; Glutaminase; Glutamine; Humans; Pyruvic Acid; Thiadiazoles; Triple Negative Breast Neoplasms; Tumor Cells, Cultured; Tumor Microenvironment

2020
Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers.
    Cancer research, 2020, 10-15, Volume: 80, Issue:20

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Glutaminase; Glutamine; Glutathione; Humans; Mice, Nude; Ovarian Neoplasms; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-myc; Thiadiazoles; Xenograft Model Antitumor Assays

2020
A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues.
    Journal of genetics and genomics = Yi chuan xue bao, 2020, 07-20, Volume: 47, Issue:7

    Topics: Animals; Benzeneacetamides; Cell Line, Tumor; Colonic Neoplasms; Glutaminase; Glutamine; Heterografts; Humans; Mice; Thiadiazoles

2020
A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer.
    eLife, 2020, 10-05, Volume: 9

    Topics: Amino Acid Transport System ASC; Animals; Antineoplastic Agents; Apoptosis; Benzeneacetamides; Carrier Proteins; Cell Line, Tumor; Drug Synergism; Glutaminase; Glutamine; Humans; Liver Neoplasms; Mice; Minor Histocompatibility Antigens; Reactive Oxygen Species; Thiadiazoles; Xenograft Model Antitumor Assays

2020
The glutaminase inhibitor telaglenastat enhances the antitumor activity of signal transduction inhibitors everolimus and cabozantinib in models of renal cell carcinoma.
    PloS one, 2021, Volume: 16, Issue:11

    Topics: Anilides; Animals; Benzeneacetamides; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Everolimus; Female; Gene Expression Regulation, Neoplastic; Glucose; Glutaminase; Glutamine; Humans; Kidney Neoplasms; Mice; Pyridines; Signal Transduction; Thiadiazoles; Xenograft Model Antitumor Assays

2021
Heterogeneity of glutamine metabolism in acquired-EGFR-TKI-resistant lung cancer.
    Life sciences, 2022, Feb-15, Volume: 291

    Topics: Apoptosis; Benzeneacetamides; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Drug Resistance, Neoplasm; ErbB Receptors; Glutamine; Humans; Lung Neoplasms; Mutation; Protein Kinase Inhibitors; Tandem Mass Spectrometry; Thiadiazoles; Xenograft Model Antitumor Assays

2022
Mesothelioma cancer cells are glutamine addicted and glutamine restriction reduces YAP1 signaling to attenuate tumor formation.
    Molecular carcinogenesis, 2023, Volume: 62, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Amino Acid Transport System ASC; Cell Line, Tumor; Cell Proliferation; Glutamine; Humans; Mesothelioma; Mesothelioma, Malignant; Minor Histocompatibility Antigens; Transcription Factors; YAP-Signaling Proteins

2023
Differential Effects of Glutamine Inhibition Strategies on Antitumor CD8 T Cells.
    Journal of immunology (Baltimore, Md. : 1950), 2023, 08-15, Volume: 211, Issue:4

    Topics: Animals; CD8-Positive T-Lymphocytes; Diazooxonorleucine; Glutamine; Mice; Neoplasms

2023