glutamine and azaserine

glutamine has been researched along with azaserine in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-199053 (79.10)18.7374
1990's5 (7.46)18.2507
2000's7 (10.45)29.6817
2010's2 (2.99)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Seegmiller, JE; Willis, RC1
Tritz, GJ; Williams, MV1
Campbell, JA; Edwards, JG; Robson, RT; Vicker, MG1
Jones, RA1
Goh, SH; Léjohn, HB1
Rando, RR1
Candau, P; Florencio, FJ; Mérida, A1
Ahmed, A; Low, SY; Pogson, CI; Rennie, MJ; Taylor, PM1
Bacote, V; Marshall, S; Traxinger, RR1
Christopherson, RI; Lyons, SD; Sant, ME1
Prajda, N1
Becker, MA; Kim, M1
de Jong, AJ; Douglas, BR; Jansen, JB; Lamers, CB; Rovati, LC; Woutersen, RA2
Hu, CZ; Li, JD; Yoch, DC1
Kanemoto, RH; Ludden, PW1
Archer, MC; Chan, AM; Zucker, PF1
Kaufman, ER1
Dunn, SD; Klucas, RV1
Chu, SH; Crabtree, GW; Parks, RE; Scholar, EM1
Wyngaarden, JB1
Carter, SK; Cooney, DA; Livingston, RB; Venditti, JM1
Martin, DW; Murphy, B2
Feldman, RI; Taylor, MW1
Oppenheimer, SB1
Jackson, JF; Ong, BL1
Balis, ME; Miller, HK1
Srinivasan, PR; Tamir, H1
Protivinsky, R1
Cooney, DA; Davis, RD; Pittillo, RF; Rosenkrantz, H; Schaeppi, U; Sprague, R1
Chu, SY; Henderson, JF1
Henderson, ES; Leventhal, BG1
Macadam, RF; McCallum, HM1
Appel, SH; Howard, WJ; Kerson, LA1
Canellos, GP; Haskell, CM1
Mountain, IM; Stock, CC; Tarnowski, GS1
Buchanan, JM; Frère, JM; Schroeder, DD1
Gale, GR; Schmidt, GB1
Fridland, A; Scholefield, PG1
Hager, SE; Jones, ME1
Neal, AL; Smulson, ME1
Hsu, BY; Marshall, CM; McNamara, PD; Segal, S1
Karasawa, Y; Kibe, K1
Aharony, D; Dobson, P1
Arakawa, M; Ardalan, B; Cooney, DA; Jayaram, H; Villacorte, D1
DeMoss, JA; Henkin, J; Keesey, J; Paukert, JL1
Jackson, GE; Murray, GJ; Parniak, MA; Viswanatha, T1
Hong, J; Masters, PS1
Levine, RA; Taylor, MW1
Buchanan, JM1
Bertino, JR; Gritsman, H; Li, WW; Tong, WP; Waltham, MC1
Haynes, TE; Li, H; Meininger, CJ; Wu, G1
Chittur, SV; Davisson, VJ; Klem, TJ; Shafer, CM1
Näsholm, T; Persson, J1
BUCHANAN, JM; DAWID, IB; FRENCH, TC1
EHRENFELD, E; MARBLE, SJ; MEISTER, A1
ANDERSON, EP; BROCKMAN, RW1
LEE, KH; YUZURIHA, Y1
BRZOZOWSKI, T; DUFFIELD, PH; KALMAN, SM1
JAFFE, JJ; MOMPARLER, RL1
Dalen, KT; Gnudi, L; Grønning, LM; Hardy, K; Jat, PS; Shepherd, PR; Tingsabadh, R1
Chatham, JC; Liu, J; Marchase, RB1
Huang, Z; Liang, M; Peng, J; Wang, X; Xing, T1
Fukuyama, K; Hiratake, J; Irie, M; Kumagai, H; Okada, T; Suzuki, H; Wada, K; Yamada, C1
Chen, K; Deussen, ZA; Liu, JL; Siswick, MY; Tastan, ÖY; Zhang, J1
Benson, CC; Clish, CB; Gonzalez Herrera, KN; Gorham, JM; Haigis, MC; Ishikawa, Y; Lin, JR; Mulei, S; Ringel, A; Satterstrom, FK; Seidman, JG; Sorger, PK; Souza, A; Spinelli, JB; Yoon, H; Zaganjor, E1

Reviews

4 review(s) available for glutamine and azaserine

ArticleYear
Glutamine phosphoribosylpyrophosphate amidotransferase.
    Current topics in cellular regulation, 1972, Volume: 5

    Topics: Animals; Azaserine; Binding Sites; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Diazooxonorleucine; Glutamine; Iron; Kinetics; Leucine; Liver; Magnesium; Molecular Weight; Multienzyme Complexes; Mutation; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Protein Binding; Protein Conformation; Ribonucleotides; Sulfhydryl Compounds

1972
Glutamine antagonists in chemotherapy.
    Advances in pharmacology and chemotherapy, 1970, Volume: 8

    Topics: Adult; Aminobutyrates; Animals; Asparaginase; Azaserine; Azo Compounds; Child; Diazooxonorleucine; Drug Combinations; Drug Interactions; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Humans; Hydroxylysine; Leukemia; Leukemia L1210; Liver; Methionine Sulfoximine; Mice; Neoplasms; Rats; RNA, Transfer

1970
Azaserine.
    Antibiotics and chemotherapy, 1971, Volume: 17

    Topics: Amino Acids; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Azaserine; Bacteria; Binding, Competitive; Chick Embryo; Glutamine; Humans; Rickettsia; Shikimic Acid; Streptomyces; Viruses

1971
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
    Annual review of biochemistry, 1963, Volume: 32

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil

1963

Other Studies

63 other study(ies) available for glutamine and azaserine

ArticleYear
The inhibition by 6-diazo-5-oxo-l-norleucine of glutamine catabolism of the cultured human lymphoblast.
    Journal of cellular physiology, 1977, Volume: 93, Issue:3

    Topics: Azaserine; Azo Compounds; Cell Line; Diazooxonorleucine; gamma-Glutamyltransferase; Glutaminase; Glutamine; Rotenone

1977
Studies on the modes of action of azaserine inhibition of Escherichia coli. Potentiation of phenylalanine reversal.
    The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:1

    Topics: Alanine; Asparagine; Azaserine; Drug Resistance, Microbial; Drug Synergism; Escherichia coli; Glutamine; Methionine; Mutation; Niacinamide; p-Fluorophenylalanine; Phenylalanine; Stereoisomerism

1977
Trypsinized BHK21 cells aggregate in the presence of metabolic inhibitors and in the absence of divalent cations.
    Journal of cell science, 1975, Volume: 19, Issue:3

    Topics: 4-Chloromercuribenzenesulfonate; Azaserine; Bucladesine; Cations, Divalent; Cell Adhesion; Cell Aggregation; Cell Line; Cobalt; Cyanides; Cycloheximide; Cytochalasin B; Deoxyglucose; Electron Transport; Fluorides; Glucose; Glutamine; Glycolysis; Hexosamines; Manganese; Protein Biosynthesis; Rotenone; Sodium; Temperature; Trypsin

1975
Evidence for cycloheximide acting as a glutamine analogue in plant tissue.
    Biochimica et biophysica acta, 1977, Jan-03, Volume: 474, Issue:1

    Topics: Asparagine; Azaserine; Cycloheximide; Edetic Acid; Glutamine; Plants; Protein Biosynthesis; Puromycin; Zea mays

1977
Genetical and biochemical evidence that a novel dinucleoside polyphosphate coordinates salvage and de novo nucleotide biosynthetic pathways in mammalian cells.
    Biochemical and biophysical research communications, 1977, Jan-10, Volume: 74, Issue:1

    Topics: Azaserine; Cell Line; Fluorouracil; Genes; Glutamine; Guanosine Triphosphate; Methotrexate; Mutation; Oligonucleotides; Oligoribonucleotides; Ribonucleotides

1977
On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors.
    Biochemical pharmacology, 1975, Jun-15, Volume: 24, Issue:11-12

    Topics: Alanine; Anti-Bacterial Agents; Asparagine; Azaserine; Azo Compounds; Carbamates; Catalysis; Cell Wall; Cephalosporins; Cycloserine; Diazooxonorleucine; Enzyme Inhibitors; Glutamine; Models, Chemical; Models, Molecular; Penicillins; Purines; Pyridoxal Phosphate; Pyrimidines; Racemases and Epimerases; Serine

1975
Regulation of glutamine synthetase activity in the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 by the nitrogen source: effect of ammonium.
    Journal of bacteriology, 1991, Volume: 173, Issue:13

    Topics: Ammonia; Azaserine; Culture Media; Cyanobacteria; Enzyme Activation; Glutamate-Ammonia Ligase; Glutamine; Ketoglutaric Acids; Nitrates; Nitrogen

1991
Substrate-specificity of glutamine transporters in membrane vesicles from rat liver and skeletal muscle investigated using amino acid analogues.
    The Biochemical journal, 1991, Aug-15, Volume: 278 ( Pt 1)

    Topics: Amino Acids; Amino Acids, Cyclic; Aminoisobutyric Acids; Animals; Azaserine; Biological Transport; Carrier Proteins; Cell Membrane; Diazooxonorleucine; Female; Glutamine; Kinetics; Lithium; Liver; Muscles; Rats; Rats, Inbred Strains; Sarcolemma; Sodium

1991
Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance.
    The Journal of biological chemistry, 1991, Mar-15, Volume: 266, Issue:8

    Topics: Animals; Azaserine; Biological Transport; Glucosamine; Glucose; Glutamine; Hexosamines; Insulin Resistance; Male; Rats; Rats, Inbred Strains

1991
Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Animals; Azaserine; Azo Compounds; Carbon-Nitrogen Ligases; Cell Line; Chromatography, High Pressure Liquid; Diazooxonorleucine; Glutamine; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Isoxazoles; Leukemia L1210; Ligases; Mice; Nucleotides; Oxazoles; Spectrophotometry, Ultraviolet

1990
Enzyme targets of antiglutamine agents in cancer chemotherapy.
    Advances in enzyme regulation, 1985, Volume: 24

    Topics: Animals; Anthranilate Synthase; Antibiotics, Antineoplastic; Azaserine; Drug Synergism; Glutamine; Isoxazoles; Liver; Liver Neoplasms, Experimental; Nitrogenous Group Transferases; Oxazoles; Phosphoribosyl Pyrophosphate; Rats; Ribonucleotides; Transferases

1985
Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate.
    The Journal of biological chemistry, 1987, Oct-25, Volume: 262, Issue:30

    Topics: Azaserine; Cells, Cultured; Fibroblasts; Glutamine; Humans; Hypoxanthine Phosphoribosyltransferase; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Ribose-Phosphate Pyrophosphokinase

1987
Modulation by CR-1409 (lorglumide), a cholecystokinin receptor antagonist, of trypsin inhibitor-enhanced growth of azaserine-induced putative preneoplastic lesions in rat pancreas.
    Cancer research, 1989, May-01, Volume: 49, Issue:9

    Topics: Animals; Azaserine; Cholecystokinin; Esters; Gabexate; Glutamine; Guanidines; Male; Pancreatic Neoplasms; Precancerous Conditions; Proglumide; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Sincalide; Trypsin Inhibitors

1989
Changes in amino acid and nucleotide pools of Rhodospirillum rubrum during switch-off of nitrogenase activity initiated by NH4+ or darkness.
    Journal of bacteriology, 1987, Volume: 169, Issue:1

    Topics: Amino Acids; Ammonia; Azaserine; Darkness; Glutamates; Glutamic Acid; Glutamine; Kinetics; Nitrogenase; Nucleotides; Rhodospirillum rubrum

1987
Amino acid concentrations in Rhodospirillum rubrum during expression and switch-off of nitrogenase activity.
    Journal of bacteriology, 1987, Volume: 169, Issue:7

    Topics: Amino Acids; Ammonia; Azaserine; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Light; Methionine Sulfoximine; Methylphenazonium Methosulfate; Nitrogen; Nitrogenase; Rhodospirillum

1987
Influence of cholecystokinin antagonist on the effects of cholecystokinin and bombesin on azaserine-induced lesions in rat pancreas.
    Gastroenterology, 1989, Volume: 96, Issue:2 Pt 1

    Topics: Animals; Azaserine; Bombesin; Cholecystokinin; Glutamine; Male; Pancreas; Proglumide; Rats; Rats, Inbred Strains

1989
Cellular toxicity of pancreatic carcinogens.
    Journal of the National Cancer Institute, 1986, Volume: 76, Issue:6

    Topics: Animals; Azaserine; Carcinogens; Cricetinae; Glutamine; Leucine; Male; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Protein Biosynthesis; Rats; Rats, Inbred Strains; Streptozocin; Tritium

1986
Isolation and characterization of a mutant Chinese hamster cell line resistant to the glutamine analog 6-diazo-5-oxo-L-norleucine.
    Somatic cell and molecular genetics, 1985, Volume: 11, Issue:1

    Topics: Animals; Azaserine; Azo Compounds; Carbon-Nitrogen Ligases; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Cell Line; Cricetinae; Cricetulus; Diazooxonorleucine; Drug Resistance; Glutamine; Ligases; Nucleosides; Phenotype; Ribonucleotides

1985
Studies on possible routes of ammonium assimilation in soybean root nodule bacteroids.
    Canadian journal of microbiology, 1973, Volume: 19, Issue:12

    Topics: Alanine; Amino Acid Oxidoreductases; Ammonium Chloride; Azaserine; Carbon Radioisotopes; Cell-Free System; Chloromercuribenzoates; Chromatography, Thin Layer; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamine; Glycine max; Hydrogen-Ion Concentration; Ketoglutaric Acids; NAD; Nitrogen; Plants; Pyruvates; Rhizobium; Spectrophotometry

1973
Inhibition of purine biosynthesis de novo in sarcoma 180 ascites cells by mercapto and seleno purine analogs.
    Biochemical pharmacology, 1973, Jan-15, Volume: 22, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Azaserine; Carbon Radioisotopes; Feedback; Female; Glutamine; Glycine; Mercaptopurine; Mice; Mice, Inbred Strains; Pentosephosphates; Pentosyltransferases; Phosphoric Acids; Purine Nucleosides; Purines; Pyrazoles; Pyrimidinones; Ribonucleosides; Sarcoma 180; Selenium; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1973
Carbamyl phosphate and glutamine stimulation of the gallbladder salt pump.
    The Journal of membrane biology, 1974, Volume: 18, Issue:3-4

    Topics: Acetates; Animals; Asparagine; Aspartic Acid; Azaserine; Bicarbonates; Biological Transport, Active; Carbamates; Gallbladder; Glutamates; Glutamine; Hydrogen-Ion Concentration; Kinetics; Organophosphorus Compounds; Rabbits; Sodium Chloride; Water

1974
Purine mutants of mammalian cell lines. I. Accumulation of formylglycinamide ribotide by purine mutants of Chinese hamster ovary cells.
    Biochemical genetics, 1974, Volume: 12, Issue:5

    Topics: Animals; Azaserine; Cell Line; Clone Cells; Cricetinae; Female; Formates; Glutamine; Glycine; Hypoxanthines; Ligases; Mutation; Ovary; Pentosephosphates; Purines; RNA; Uridine

1974
Utilization of L-glutamine in intercellular adhesion: ascites tumor and embryonic cells.
    Experimental cell research, 1973, Mar-15, Volume: 77, Issue:1

    Topics: Animals; Azaserine; Carcinoma, Ehrlich Tumor; Cell Adhesion; Cell Aggregation; Cells, Cultured; Chick Embryo; Culture Media; Cytological Techniques; Glutamine; Indicators and Reagents; Liver Neoplasms; Mice; Norleucine; Retina; Sarcoma 180; Time Factors; Trypsin

1973
Pyrimidine nucleotide biosynthesis in Phaseolus aureus. Enzymic aspects of the control of carbamoyl phosphate synthesis and utilization.
    The Biochemical journal, 1972, Volume: 129, Issue:3

    Topics: Adenosine Triphosphate; Ammonia; Aspartate Carbamoyltransferase; Azaserine; Carbamates; Carbon Isotopes; Escherichia coli; Glutamine; Magnesium; Nucleotides; Ornithine Carbamoyltransferase; Phosphates; Phosphotransferases; Plants; Purine Nucleotides; Pyrimidine Nucleotides

1972
Carbamyl phosphate synthetase II in the mucosal cells of gall bladders.
    Biochemical and biophysical research communications, 1972, Oct-06, Volume: 49, Issue:1

    Topics: Animals; Azaserine; Carbamates; Carbon Isotopes; Cattle; Chromatography, Ion Exchange; Gallbladder; Glutamine; Mucous Membrane; Oxygen Consumption; Phosphotransferases; Rabbits

1972
Glutaminase activity of L-asparagine amidohydrolase.
    Biochemical pharmacology, 1969, Volume: 18, Issue:9

    Topics: Asparaginase; Asparagine; Azaserine; Carbon Isotopes; Escherichia coli; Glutaminase; Glutamine; Hydrogen-Ion Concentration; Kinetics; Leucine

1969
Purification and properties of anthranilate synthase from Salmonella typhimurium.
    The Journal of biological chemistry, 1969, Dec-10, Volume: 244, Issue:23

    Topics: Ammonia; Azaserine; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Culture Media; Cyclohexanecarboxylic Acids; Drug Stability; Electrophoresis; Feedback; Glutamine; Hydrogen-Ion Concentration; Kinetics; Mercury; Methods; Molecular Weight; ortho-Aminobenzoates; Quaternary Ammonium Compounds; Salmonella typhimurium; Solubility; Transaminases; Tryptophan

1969
The stoichiometric fate of azaserine metabolized in vitro by tissues from azaserine-treated dogs and mice.
    Toxicology and applied pharmacology, 1972, Volume: 22, Issue:4

    Topics: Ammonia; Animals; Azaserine; Azo Compounds; Chromatography, Ion Exchange; Dogs; Female; Glutamine; Glycolates; Kidney; Liver; Male; Mice; Mice, Inbred Strains; Prostate; Pyruvates; Rats; Rats, Inbred Strains; Salivary Glands; Spectrophotometry

1972
Inhibition of the phosphoribosyl-formylglycineamidine synthetase of Ehrlich ascites tumor cells by glutamine analogues.
    Biochemical pharmacology, 1972, Feb-01, Volume: 21, Issue:3

    Topics: Animals; Azaserine; Carcinoma, Ehrlich Tumor; Diazooxonorleucine; Glutamine; Glycine; Kinetics; Ligases; Osmolar Concentration; Parabens; Pentosephosphates; Protein Binding

1972
Therapy of acute leukemia with drug combinations which include asparaginase.
    Cancer, 1971, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Azaserine; Child; Child, Preschool; Cytarabine; Female; Glutamine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Remission, Spontaneous; Vincristine

1971
Fine structure of the GAAN effect and lathyrism in cultured chick cartilage.
    Experimental and molecular pathology, 1969, Volume: 11, Issue:2

    Topics: Animals; Azaserine; Bone Development; Cartilage; Chick Embryo; Glutamates; Glutamine; Hindlimb; In Vitro Techniques; Lathyrism; Microscopy, Electron; Nitriles; Tibia; Transaminases

1969
Synthesis de novo of purines in slices of rat brain and liver.
    Journal of neurochemistry, 1970, Volume: 17, Issue:1

    Topics: Animals; Azaserine; Centrifugation; Cerebral Cortex; Chromatography, DEAE-Cellulose; Chromatography, Paper; Chromatography, Thin Layer; Glucose; Glutamine; Glycine; In Vitro Techniques; Liver; Male; Purines; Rats; Spectrum Analysis

1970
Asparagine biosynthesis in human KB tumor cells: inhibitor studies with asparagine and glutamine antagonists.
    Cancer research, 1970, Volume: 30, Issue:4

    Topics: Amino Acids; Anti-Bacterial Agents; Asparagine; Aspartic Acid; Azaserine; Azo Compounds; Carcinoma; Cell Line; Culture Techniques; Glutamine; Humans; Ligases; Mouth Neoplasms; Puromycin

1970
Combination therapy of animal tumors with L-asparaginase and antagonists of glutamine or glutamic acid.
    Cancer research, 1970, Volume: 30, Issue:4

    Topics: Amino Acids; Aminobutyrates; Animals; Asparaginase; Azaserine; Body Weight; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Drug Synergism; Excitatory Amino Acid Antagonists; Female; Glutamine; Hexoses; Male; Melanoma; Mice; Neoplasms, Experimental; Rats

1970
Biosynthesis of the purines. XXXV. Reversible polymerization of formylglycinamide ribonucleotide amidotransferase.
    The Journal of biological chemistry, 1971, Aug-10, Volume: 246, Issue:15

    Topics: Adenosine Triphosphate; Animals; Azaserine; Binding Sites; Chemical Precipitation; Chickens; Chromatography; Chromatography, Gel; Detergents; Electrophoresis; Formates; Glutamine; Glycine; Ligases; Liver; Macromolecular Substances; Mercaptoethanol; Polymers; Purines; Quaternary Ammonium Compounds; Sulfates; Sulfhydryl Reagents; Sulfides; Sulfuric Acids; Tetroses

1971
Mode of action of alanosine.
    Biochemical pharmacology, 1968, Volume: 17, Issue:3

    Topics: Adenine; Animals; Antifungal Agents; Antiviral Agents; Aspartic Acid; Azaserine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Depression, Chemical; Formates; Glutamine; Glycine; Guanine; Leucine; Nitrosamines; Nucleotides; Propionates; RNA, Neoplasm; Thymidine; Tritium; Uridine

1968
Nucleotide metabolism in Ehrlich ascites carcinoma cells.
    Biochimica et biophysica acta, 1969, Jun-17, Volume: 182, Issue:2

    Topics: Adenine; Animals; Azaserine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cell-Free System; Cytosine Nucleotides; Electrophoresis; Glucose; Glutamine; Nucleosides; Nucleotides; Phosphorus Isotopes; Phosphotransferases; Ribose; RNA, Neoplasm; Uracil; Uridine

1969
Initial steps in pyrimidine synthesis in Ehrlich ascites carcinoma in vitro. 1. Factors affecting the incorporation of 14C-bicarbonate into carbon 2 of the uracil ring of the acid-soluble nucleotides of intact cells.
    The Journal of biological chemistry, 1965, Volume: 240, Issue:12

    Topics: Ammonia; Animals; Azaserine; Bicarbonates; Carbamates; Carcinoma, Ehrlich Tumor; Glucose; Glutamine; In Vitro Techniques; Orotic Acid; Phosphates; Serine; Uracil; Uracil Nucleotides

1965
Comparative effects of glutamine analogues on protein metabolism of 6C3H-ED and Ehrlich ascites carcinoma.
    Archives of biochemistry and biophysics, 1965, Volume: 112, Issue:1

    Topics: Amides; Animals; Azaserine; Azides; Carcinoma, Ehrlich Tumor; Diazooxonorleucine; Glutamine; Hydroxamic Acids; In Vitro Techniques; Isoleucine; Lymphoma, Non-Hodgkin; Methionine; Methionine Sulfoximine; Neoplasm Proteins; Sarcoma, Experimental; Valine

1965
The effect of azaserine on glutamine uptake by rat renal brush-border membranes.
    The Biochemical journal, 1980, Oct-15, Volume: 192, Issue:1

    Topics: Animals; Azaserine; Biological Transport; Cell Membrane; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Glutamine; In Vitro Techniques; Kidney Cortex; Kinetics; Male; Microvilli; Rats

1980
Effects of azaserine treatment on plasma glutamine concentration and uric acid production in chickens fed low and high protein diets.
    The Journal of nutrition, 1982, Volume: 112, Issue:9

    Topics: Acetates; Ammonia; Animals; Azaserine; Chickens; Dietary Proteins; Glutamate-Ammonia Ligase; Glutamine; Liver; Male; Uric Acid

1982
Discriminative effect of gamma-glutamyl transpeptidase inhibitors on metabolism of leukotriene C4 in peritoneal cells.
    Life sciences, 1984, Nov-19, Volume: 35, Issue:21

    Topics: Aniline Compounds; Animals; Ascitic Fluid; Azaserine; Boric Acids; Calcimycin; Cattle; Diazooxonorleucine; gamma-Glutamyltransferase; Glutamates; Glutamine; Kidney; Kinetics; Rats; Serine; SRS-A

1984
Effect of L-glutamine antagonists on 5-phosphoribosyl 1-pyrophosphate levels in P388 leukemia and in murine colon adenocarcinomas in vivo.
    Biochemical pharmacology, 1982, Apr-15, Volume: 31, Issue:8

    Topics: Adenocarcinoma; Animals; Azaserine; Colonic Neoplasms; Diazooxonorleucine; Glutamine; Intestine, Small; Isoxazoles; Leukemia P388; Leukemia, Experimental; Mice; Neoplasms, Experimental; Pentosephosphates; Phosphoribosyl Pyrophosphate

1982
Anthranilate synthase of Neurospora crassa: reaction and labeling with glutamine analogs.
    Archives of biochemistry and biophysics, 1982, Oct-15, Volume: 218, Issue:2

    Topics: Anthranilate Synthase; Azaserine; Diazooxonorleucine; Glutamine; Kinetics; Magnesium; Neurospora; Neurospora crassa

1982
Stimulation by glutamine of the formation of N6-hydroxylysine in a cell-free extract from Aerobacter aerogenes 62-1.
    Journal of cellular biochemistry, 1984, Volume: 24, Issue:4

    Topics: Azaserine; Cell-Free System; Enterobacter; Enterobacteriaceae; Glutamates; Glutamine; Hydroxylation; Hydroxylysine; Lysine; Stimulation, Chemical

1984
Reconstitution of binding protein dependent active transport of glutamine in spheroplasts of Escherichia coli.
    Biochemistry, 1981, Aug-18, Volume: 20, Issue:17

    Topics: Arsenates; Azaserine; Biological Transport, Active; Escherichia coli; Glutamine; Kinetics; Spheroplasts

1981
Regulation of purE transcription in a purE::lac fusion strain of Escherichia coli.
    Journal of bacteriology, 1982, Volume: 149, Issue:3

    Topics: Adenine; Azaserine; DNA, Recombinant; Escherichia coli; Gene Expression Regulation; Genes, Bacterial; Genes, Regulator; Glutamine; Purines; Pyrimidines; Transcription, Genetic

1982
Covalent reaction of substrates and antimetabolites with formylglycinamide ribonucleotide amidotransferase.
    Methods in enzymology, 1982, Volume: 87

    Topics: Alkylating Agents; Animals; Antimetabolites; Azaserine; Binding Sites; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Chickens; Glutamine; Kinetics; Ligases; Substrate Specificity

1982
gamma-Glutamyl hydrolase from human sarcoma HT-1080 cells: characterization and inhibition by glutamine antagonists.
    Molecular pharmacology, 1997, Volume: 51, Issue:5

    Topics: Azaserine; Diazooxonorleucine; Enzyme Inhibitors; gamma-Glutamyl Hydrolase; Glutamine; Humans; Isoxazoles; Kinetics; Methotrexate; Sarcoma; Substrate Specificity; Tumor Cells, Cultured

1997
Glutamine metabolism in endothelial cells: ornithine synthesis from glutamine via pyrroline-5-carboxylate synthase.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2000, Volume: 126, Issue:1

    Topics: Alanine; Ammonia; Animals; Antimetabolites, Antineoplastic; Aorta; Asparagine; Aspartic Acid; Azaserine; Carbon Dioxide; Cattle; Cells, Cultured; Diazooxonorleucine; Endothelium, Vascular; Enzymes; Glutamic Acid; Glutamine; Humans; Microcirculation; Ornithine; Ornithine-Oxo-Acid Transaminase; Umbilical Veins; Venules

2000
Mechanism for acivicin inactivation of triad glutamine amidotransferases.
    Biochemistry, 2001, Jan-30, Volume: 40, Issue:4

    Topics: Amino Acid Sequence; Aminohydrolases; Anthranilate Synthase; Azaserine; Binding, Competitive; Carbon-Nitrogen Ligases; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Diazooxonorleucine; Enzyme Inhibitors; Escherichia coli; Glutamine; Isoxazoles; Kinetics; Molecular Sequence Data; Multienzyme Complexes; Nitrogenous Group Transferases; Ribonucleotides; Saccharomyces cerevisiae; Static Electricity; Stereoisomerism; Substrate Specificity

2001
Regulation of amino acid uptake in conifers by exogenous and endogenous nitrogen.
    Planta, 2002, Volume: 215, Issue:4

    Topics: Adaptation, Physiological; Amino Acids; Aminooxyacetic Acid; Azaserine; Enzyme Inhibitors; Glutamate Synthase; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Methionine Sulfoximine; Nitrate Reductase; Nitrate Reductases; Nitrates; Nitrogen; Plant Roots; Quaternary Ammonium Compounds; Tracheophyta; Transaminases; Tungsten Compounds; Up-Regulation

2002
Azaserine-reactive sulfhydryl group of 2-formamido-N-ribosylacetamide 5'-phosphate: L-glutamine amido-ligase (adenosine diphosphate). II. Degradation of azaserine-C-14-labeled enzyme.
    The Journal of biological chemistry, 1963, Volume: 238

    Topics: Adenosine Diphosphate; Azaserine; Glutamine; Ligases; Phosphates; Salmonella; Sulfhydryl Compounds

1963
ENZYMATIC SYNTHESIS OF GAMMA-GLUTAMYLHYDROXAMIC ACID FROM GLUTAMIC ACID AND HYDROXYLAMINE.
    The Journal of biological chemistry, 1963, Volume: 238

    Topics: Amidohydrolases; Ammonia; Antimetabolites; Asparagine; Azaserine; Azotobacter; Carbon Isotopes; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Hydroxamic Acids; Hydroxylamine; Hydroxylamines; Pharmacology; Proteins; Research; Streptomycin

1963
STUDIES OF CELL GROWTH AND CELL DIVISION. III. ACTION OF AZASERINE ON CELL DIVISION.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Azaserine; Azo Compounds; Cell Cycle; Cell Division; Glutamine; Metabolism; Pharmacology; Phenylalanine; Purines; Research; Tetrahymena

1964
IDENTITY IN ESCHERICHIA COLI OF CARBAMYL PHOSPHOKINASE AND AN ACTIVITY WHICH CATALYZES AMINO GROUP TRANSFER FROM GLUTAMINE TO ORNITHINE IN CITRULLINE SYNTHESIS.
    Biochemical and biophysical research communications, 1965, Feb-17, Volume: 18

    Topics: Amino Acids; Azaserine; Biochemical Phenomena; Biochemistry; Carbamates; Chromatography; Citrulline; Electrophoresis; Escherichia coli; Fluorides; Glutamine; Ketoglutaric Acids; Ornithine; Pharmacology; Phosphotransferases; Phosphotransferases (Carboxyl Group Acceptor); Research; Sulfhydryl Compounds

1965
EFFECT OF AZASERINE ON THE INCORPORATION OF 14-C-LABELED PURINES AND PYRIMIDINES INTO ACID-SOLUBLE AND NUCLEIC ACID FRACTIONS OF TRYPANOSOMA EQUIPERDUM.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Adenine; Amino Acids; Azaserine; Cytosine; Cytosine Nucleotides; DNA; Glutamine; Guanine; Hypoxanthines; Leucine; Metabolism; Nucleic Acids; Orotic Acid; Pharmacology; Purines; Pyrimidines; Research; RNA; Thymine; Trypanosoma; Tryptophan; Tyrosine; Uracil; Uracil Nucleotides

1965
Glucose induces increases in levels of the transcriptional repressor Id2 via the hexosamine pathway.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:4

    Topics: Animals; Azaserine; Enzyme Inhibitors; Gene Expression Regulation; Glucosamine; Glucose; Glutamine; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Hexosamines; Inhibitor of Differentiation Protein 2; Macrophages; Mice; Nitrogenous Group Transferases; Repressor Proteins; Sterol Esterase; Sterol Regulatory Element Binding Protein 1

2006
Glutamine-induced protection of isolated rat heart from ischemia/reperfusion injury is mediated via the hexosamine biosynthesis pathway and increased protein O-GlcNAc levels.
    Journal of molecular and cellular cardiology, 2007, Volume: 42, Issue:1

    Topics: Acetylglucosamine; Adenosine Triphosphate; Alloxan; Animals; Azaserine; Cardiotonic Agents; Glutamine; Glycosylation; Hexosamines; In Vitro Techniques; Male; Myocardial Reperfusion Injury; N-Acetylglucosaminyltransferases; Rats; Rats, Sprague-Dawley; Uridine Diphosphate N-Acetylglucosamine

2007
Exogenous ammonium inhibits petal pigmentation and expansion in Gerbera hybrida.
    Physiologia plantarum, 2008, Volume: 133, Issue:2

    Topics: Anthocyanins; Asteraceae; Azaserine; Cells, Cultured; Flowers; Gene Expression Regulation, Plant; Genes, Plant; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Methionine Sulfoximine; Pigmentation; Quaternary Ammonium Compounds; Time Factors

2008
Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists.
    Journal of molecular biology, 2008, Jul-04, Volume: 380, Issue:2

    Topics: Amino Acid Sequence; Animals; Azaserine; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli Proteins; gamma-Glutamyltransferase; Glutamine; Humans; Isoxazoles; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment

2008
Glutamine analogs promote cytoophidium assembly in human and Drosophila cells.
    Journal of genetics and genomics = Yi chuan xue bao, 2011, Sep-20, Volume: 38, Issue:9

    Topics: Animals; Apoptosis; Azaserine; Carbon-Nitrogen Ligases; Cell Compartmentation; Cell Cycle; Diazooxonorleucine; Drosophila melanogaster; Enzyme Inhibitors; Female; Glutamine; HeLa Cells; Humans; Intracellular Space; Male; Oogenesis; RNA Interference

2011
Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3.
    Cell reports, 2018, 02-20, Volume: 22, Issue:8

    Topics: Amino Acid Sequence; Animals; Azaserine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Fibroblasts; Glutamine; Mechanistic Target of Rapamycin Complex 1; Mice, Knockout; Mice, Nude; Nucleotides; Promoter Regions, Genetic; Signal Transduction; Sirtuin 3; Small Molecule Libraries; Up-Regulation

2018