glutamine has been researched along with alpha-hydroxyglutarate in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 13 (81.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Jakobs, C; Roos, B; Struys, EA; Verhoeven, NM | 1 |
| Durán, RV; Hall, MN | 1 |
| Bachoo, R; Choi, C; Deberardinis, R; Dimitrov, I; Ganji, S; Hulsey, K; Kovacs, Z; Madan, A; Maher, E; Malloy, C; Mendelsohn, D; Mickey, B; Pichumani, K; Zhang, S | 1 |
| Ambs, S; Chan, K; Dorsey, TH; Edelman, DC; Hsu, TY; Ioffe, OB; Issaq, HJ; Karoly, ED; Killian, JK; Kittles, RA; Kurley, SJ; Lee, DH; Mathé, EA; Meltzer, PS; Mishra, P; Prieto, D; Putluri, N; Putluri, V; Samanta, S; Schiff, R; Sonavane, R; Sreekumar, A; Starks, AM; Stephens, RM; Stevenson, HS; Terunuma, A; Veenstra, TD; Wallace, TA; Westbrook, TF; Wulff, J; Yang, Y; Yfantis, HG; Yi, M; Zhou, M | 1 |
| Ito, M; Kato, K; Kato, Y; Motomura, A; Motomura, K; Natsume, A; Ohka, F; Ranjit, M; Saito, K; Senga, T; Soga, T; Wakabayashi, T | 1 |
| Bachoo, RM; Baek, HM; DeBerardinis, RJ; Kovacs, Z; Maher, EA; Malloy, CR; Mashimo, T; Mickey, B; Pichumani, K; Ratnakar, J | 1 |
| Bell, PD; Guay-Woodford, LM; Hammock, B; Hwang, VJ; Kim, J; Rand, A; Sturdivant, S; Weiss, RH; Yang, C | 1 |
| Baran, N; Cai, T; Chan, SM; Davis, RE; DiNardo, C; Flores, ER; Gonzalez, D; Haferlach, T; Jacamo, R; Konoplev, S; Konopleva, M; Li, W; Lodi, A; Ma, H; Majeti, R; Matre, P; Qi, Y; Samudio, I; Schimmer, AD; Su, X; Sweeney, SR; Tiziani, S; Velez, J; Wang, T | 1 |
| Asai, A; Colvin, H; Doki, Y; Haraguchi, N; Hata, T; Ishii, H; Kawamoto, K; Konno, M; Koseki, J; Mizushima, T; Mori, M; Nishida, N; Nishimura, J; Satoh, T; Takahashi, H; Tsunekuni, K | 1 |
| Correa, FM; Cross, JR; Di Gialleonardo, V; Granlund, KL; Keshari, KR; Lui, H; Miloushev, VZ; Poot, AJ; Salamanca-Cardona, L; Shah, H; Tee, SS; Thompson, CB | 1 |
| Dutta, T; Ghosh, T; Gonsalves, WI; Hitosugi, T; Jevremovic, D; Kumar, SK; Nair, KS; Petterson, XM; Ramakrishnan, V; Sakrikar, D; Wellik, L | 1 |
| Cai, L; DeBerardinis, RJ; Faubert, B; Gotway, GK; Grishin, NV; Guevara, G; Jiang, L; Ko, B; Li, D; McDonald, JG; McNutt, MC; Morales, NM; Ni, M; Notzon, A; Pan, C; Pascual, JM; Pei, J; Rakheja, D; Solmonson, A; Vale, G; Vu, HS; Yang, C; Zacharias, LG | 1 |
| Batsios, G; Gillespie, AM; Molloy, AR; Najac, C; Pieper, RO; Ronen, SM; Santos, RD; Subramani, E; Viswanath, P | 1 |
| Karpel-Massler, G; Nguyen, TTT; Shang, E; Siegelin, MD | 1 |
| Kery, M; Papandreou, I | 1 |
| Cai, F; Chen, F; DeBerardinis, RJ; Gao, X; Ge, WP; He, F; Lin, H; Liu, W; Luo, B; Sun, W; Vu, HS; Xing, C; Xiong, N; Xu, H; Yao, DX; Yuan, Y; Zacharias, LG; Zhang, FC; Zhao, H | 1 |
1 review(s) available for glutamine and alpha-hydroxyglutarate
| Article | Year |
|---|---|
Emerging strategies to target cancer metabolism and improve radiation therapy outcomes.
Topics: Adaptation, Physiological; Animals; Ataxia Telangiectasia Mutated Proteins; DNA; DNA Damage; DNA Repair; Genomic Instability; Glutamine; Glutarates; Glutathione; Humans; Immunotherapy; Isocitrate Dehydrogenase; Ketoglutaric Acids; Lipid Peroxidation; Mice; Neoplasms; Nucleotides; Oxygen Consumption; Phospholipids; Radiation Tolerance; Radiation-Sensitizing Agents; Reactive Oxygen Species; Stress, Physiological; Treatment Outcome; Tumor Microenvironment | 2020 |
15 other study(ies) available for glutamine and alpha-hydroxyglutarate
| Article | Year |
|---|---|
Disease-related metabolites in culture medium of fibroblasts from patients with D-2-hydroxyglutaric aciduria, L-2-hydroxyglutaric aciduria, and combined D/L-2-hydroxyglutaric aciduria.
Topics: Biomarkers; Cell Line; Culture Media; Fibroblasts; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Glutarates; Humans; Ketoglutaric Acids; Lysine; Metabolic Diseases; Stereoisomerism; Succinic Acid | 2003 |
Glutaminolysis feeds mTORC1.
Topics: Animals; Autophagy; Gene Knock-In Techniques; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Mutation; TOR Serine-Threonine Kinases | 2012 |
A comparative study of short- and long-TE ¹H MRS at 3 T for in vivo detection of 2-hydroxyglutarate in brain tumors.
Topics: Adult; Aspartic Acid; Brain Neoplasms; gamma-Aminobutyric Acid; Glioma; Glutamic Acid; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Middle Aged; Mutation; Phantoms, Imaging; Protons; Young Adult | 2013 |
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.
Topics: Alcohol Oxidoreductases; Apoptosis; Breast Neoplasms; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; MCF-7 Cells; Metabolome; Mitochondria; Mitochondrial Proteins; Prognosis; Proto-Oncogene Proteins c-myc; Receptors, Estrogen; RNA, Small Interfering; Survival Analysis; Transcriptome; Wnt Signaling Pathway | 2014 |
Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation.
Topics: Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Glioma; Glutaminase; Glutamine; Glutarates; HEK293 Cells; Humans; Isocitrate Dehydrogenase; Ketoglutaric Acids; Metabolome; Mutation; Temozolomide | 2014 |
Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas.
Topics: Carbon Isotopes; Glioma; Glutamic Acid; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spectroscopy; Mutation | 2015 |
The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate.
Topics: Animals; Cells, Cultured; Creatine Kinase; Disease Models, Animal; DNA Mutational Analysis; Enzyme Inhibitors; Female; Glutaminase; Glutamine; Glutarates; Humans; Infant; Infant, Newborn; Male; Metabolomics; Mice; Models, Genetic; Polycystic Kidney Diseases | 2015 |
Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes.
Topics: Antineoplastic Agents; Apoptosis; Benzeneacetamides; Cell Differentiation; Cell Proliferation; Energy Metabolism; Enzyme Inhibitors; Glutamate Dehydrogenase; Glutamic Acid; Glutaminase; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Mutation; Protein Isoforms; Sulfides; Thiadiazoles | 2016 |
Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer.
Topics: Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Glutamine; Glutarates; HCT116 Cells; HEK293 Cells; Histones; HT29 Cells; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasm Metastasis; Promoter Regions, Genetic; Zinc Finger E-box-Binding Homeobox 1 | 2016 |
In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors.
Topics: Animals; Biomarkers, Tumor; Bone Neoplasms; Cell Line, Tumor; Chondrosarcoma; Female; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Imaging; Male; Mice, SCID; Mutation; Xenograft Model Antitumor Assays | 2017 |
Glutamine-derived 2-hydroxyglutarate is associated with disease progression in plasma cell malignancies.
Topics: Biomarkers, Tumor; Cell Line, Tumor; Citric Acid Cycle; Disease Progression; DNA-Binding Proteins; Glucose; Glutamine; Glutarates; Glycolysis; Humans; Lactic Acid; Multiple Myeloma; Multivariate Analysis; Neoplasms; Plasma Cells; Transcription Factors | 2018 |
Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans.
Topics: Acidosis, Lactic; Acyltransferases; Animals; Cells, Cultured; Child; Fatty Acids; Female; Fibroblasts; Glutamine; Glutarates; Humans; Lipogenesis; Lipoylation; Loss of Function Mutation; Male; Mice; Oxygen | 2019 |
PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival.
Topics: Adaptor Proteins, Signal Transducing; Animals; Astrocytes; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Transformed; Glioma; Glucose; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Mice; Neoplasm Proteins; Nuclear Magnetic Resonance, Biomolecular; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Quinoxalines; Ribosomal Protein S6 Kinases; Signal Transduction; Sulfonamides; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2019 |
Novel IDH1-Targeted Glioma Therapies.
Topics: Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Glioma; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Mutation; Poly(ADP-ribose) Polymerases; Prognosis | 2019 |
Using arterial-venous analysis to characterize cancer metabolic consumption in patients.
Topics: Acetylcarnitine; Adult; Aged; Agmatine; Biomarkers, Tumor; Blood; Blood Chemical Analysis; Blood Glucose; Blood Vessels; Brain Neoplasms; Female; Glioma; Glucose; Glutamine; Glutarates; Humans; Isocitrate Dehydrogenase; Male; Metabolomics; Middle Aged; Ornithine; Putrescine; Uridine Monophosphate; Young Adult | 2020 |