glutamine and 2-piperidone

glutamine has been researched along with 2-piperidone in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (25.81)18.2507
2000's7 (22.58)29.6817
2010's13 (41.94)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Blom, W; Hierck, L; Huijmans, JG; Kelholt-Dijkman, HH; Polder-Mol, AC1
Hara, H; Hirohata, M; Maruiwa, H; Shigemori, M; Sugita, Y; Tsuda, H1
Burzynski, SR2
Eriguchi, N; Hara, H; Kumabe, T; Nishida, H; Sugita, Y; Tsuda, H; Yoshida, H1
Hara, H; Iemura, A; Sata, M; Tsuda, H; Uchida, M; Yamana, K1
D'Avignon, DA; Revelle, LK; Wilson, JA1
Ames, MM; Buckner, JC; Cascino, TL; Figg, WD; Lim, S; Malkin, MG; Reed, E; Reid, JM; Tong, WP1
Axler, ML; Bestak, M; Burzynski, SR; Janicki, TJ; Jurida, GF; Khan, MI; Lewy, RI; Paszkowiak, JK; Szymkowski, BG; Weaver, RA1
Matono, K; Ogata, Y; Shirouzu, K1
Hammer, MR; Jonas, WB1
Burzynski, SR; Janicki, T; Jurida, G; Khan, M; Larisma, CB; Lewy, RI; Paszkowiak, J; Szymkowski, B; Weaver, R1
Bestak, M; Burzynski, SR; Janicki, TJ; Jurida, GF; Khan, MI; Lewy, RI; Szymkowski, BG; Weaver, RA1
Burzynski, SR; Dolgopolov, V; Janicki, T; Jurida, G; Khan, M; Szymkowski, B; Weaver, RA1
Burzynski, B; Burzynski, SR; Janicki, TJ; Weaver, RA1
Ackerley, DF; Copp, JN; Owen, JG1
Grzetic, J; Oomens, J1
Burzynski, GS; Burzynski, SR; Janicki, TJ; Marszalek, A2
Clerici, CA; Massimino, M1
Di Rocco, C1
Wong, TT1
Blaskiewicz, R1
Perilongo, G1
Akagi, Y; Matono, K; Ogata, Y; Shirouzu, K; Tsuda, H; Uchida, S; Ushijima, M1
Gage, D; Xu, F; Zhan, J1
Ackerley, DF; Brown, AS; Robins, KJ1
Asa, M; Ikeda, H; Iwai, T; Kitani, S; Kurniawan, YN; Nihira, T; Pait, IGU1
Ackerley, DF; Brown, AS; Calcott, MJ; Collins, VM; Owen, JG1
Guan, Y; Liu, B; Lv, D; Sun, Y; Wang, L; Yu, D1
Friedrich, MG; Schey, KL; Truscott, RJW; Wang, Z1

Reviews

1 review(s) available for glutamine and 2-piperidone

ArticleYear
Potential of antineoplastons in diseases of old age.
    Drugs & aging, 1995, Volume: 7, Issue:3

    Topics: Aged; Aging; Animals; Antineoplastic Agents; Benzeneacetamides; Drug Combinations; Glutamine; Growth Inhibitors; Humans; Neoplasms; Peptides; Phenylacetates; Piperidones

1995

Trials

10 trial(s) available for glutamine and 2-piperidone

ArticleYear
Toxicological study on antineoplastons A-10 and AS2-1 in cancer patients.
    The Kurume medical journal, 1995, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Child; Drug Combinations; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Phenylacetates; Piperidones

1995
Phase II study of antineoplastons A10 (NSC 648539) and AS2-1 (NSC 620261) in patients with recurrent glioma.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:2

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Benzeneacetamides; Brain Neoplasms; Confusion; Disorders of Excessive Somnolence; Drug Administration Schedule; Drug Combinations; Female; Glioblastoma; Glutamine; Humans; Injections, Intravenous; Male; Middle Aged; Patient Selection; Phenylacetates; Piperidones; Seizures; Severity of Illness Index; Treatment Outcome

1999
Phase II study of antineoplaston A10 and AS2-1 in patients with recurrent diffuse intrinsic brain stem glioma: a preliminary report.
    Drugs in R&D, 2003, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Cerebral Angiography; Child; Drug Combinations; Glioma; Glutamine; Humans; Karnofsky Performance Status; Phenylacetates; Piperidones; Risk Assessment; Time Factors

2003
Phase II study of antineoplaston A10 and AS2-1 in children with recurrent and progressive multicentric glioma : a preliminary report.
    Drugs in R&D, 2004, Volume: 5, Issue:6

    Topics: Adolescent; Antineoplastic Agents; Astrocytoma; Benzeneacetamides; Brain Neoplasms; Child; Child, Preschool; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Glioma; Glutamine; Humans; Infant; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome

2004
Long-term survival of high-risk pediatric patients with primitive neuroectodermal tumors treated with antineoplastons A10 and AS2-1.
    Integrative cancer therapies, 2005, Volume: 4, Issue:2

    Topics: Antineoplastic Agents; Benzeneacetamides; Brain Neoplasms; Child, Preschool; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Glutamine; Humans; Infant; Male; Neoplasm Recurrence, Local; Neuroectodermal Tumors, Primitive; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome

2005
Targeted therapy with antineoplastons A10 and AS2-1 of high-grade, recurrent, and progressive brainstem glioma.
    Integrative cancer therapies, 2006, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Benzeneacetamides; Brain Stem Neoplasms; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Glioma; Glutamine; Humans; Injections, Intravenous; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Neoplasm Recurrence, Local; Neoplasm Staging; Phenylacetates; Piperidones; Risk Assessment; Survival Analysis; Treatment Outcome

2006
The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Child; Child, Preschool; Disease Progression; Drug Combinations; Female; Glioma; Glutamine; Humans; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons; Survival Rate

2014
Commentary: The response and survival of children with recurrent diffuse intrisic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma, by Burzynski G, et al.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Biomedical Research; Brain Stem Neoplasms; Child; Child, Preschool; Disease Progression; Drug Combinations; Female; Glioma; Glutamine; Humans; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons; Prognosis; Survival Rate; Treatment Outcome

2014
Main editor's comment to the paper: the response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma. Stanislaw R. Burzynski, Tomasz J. Janicki
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Child; Child, Preschool; Disease Progression; Drug Combinations; Female; Glioma; Glutamine; Humans; Infusions, Intravenous; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons; Survival Rate; Treatment Outcome

2014
Randomized phase II study of 5-fluorouracil hepatic arterial infusion with or without antineoplastons as an adjuvant therapy after hepatectomy for liver metastases from colorectal cancer.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Chemotherapy, Adjuvant; Colorectal Neoplasms; Drug Combinations; Fluorouracil; Glutamine; Hepatectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Middle Aged; Phenylacetates; Piperidones; Survival Analysis; Treatment Outcome

2015

Other Studies

20 other study(ies) available for glutamine and 2-piperidone

ArticleYear
The detection of abnormal metabolites in MCAD deficiency: a new method.
    Journal of inherited metabolic disease, 1990, Volume: 13, Issue:3

    Topics: Acyl-CoA Dehydrogenase; Amino Acids; Chromatography, Gas; Fatty Acid Desaturases; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Mass Spectrometry; Piperidones

1990
The effect of Antineoplaston, a new antitumor agent on malignant brain tumors.
    The Kurume medical journal, 1995, Volume: 42, Issue:3

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Benzeneacetamides; Brain Neoplasms; Child; Drug Combinations; Female; Glioblastoma; Glioma; Glutamine; Humans; Male; Medulloblastoma; Middle Aged; Phenylacetates; Piperidones

1995
Inhibitory effect of antineoplaston A10 and AS2-1 on human hepatocellular carcinoma.
    The Kurume medical journal, 1996, Volume: 43, Issue:2

    Topics: Antineoplastic Agents; Benzeneacetamides; Carcinoma, Hepatocellular; Drug Combinations; Glutamine; Humans; Liver Neoplasms; Phenylacetates; Piperidones; Tumor Cells, Cultured

1996
3-[(Phenylacetyl)amino]-2,6-piperidinedione hydrolysis studies with improved synthesis and characterization of hydrolysates.
    Journal of pharmaceutical sciences, 1996, Volume: 85, Issue:10

    Topics: Antineoplastic Agents; Benzeneacetamides; Chromatography, High Pressure Liquid; Glutamic Acid; Glutamine; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Piperidones; Reference Standards

1996
Efficacy of antineoplastons A10 and AS2-1.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:6

    Topics: Antineoplastic Agents; Benzeneacetamides; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Glioma; Glutamine; Humans; National Institutes of Health (U.S.); Phenylacetates; Piperidones; Treatment Failure; United States

1999
[Anti-proliferative effects of biochemical defense modifier antineoplaston in colorectal carcinoma].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 7

    Topics: Animals; Apoptosis; Benzeneacetamides; Cell Cycle; Cell Cycle Proteins; Colorectal Neoplasms; Depression, Chemical; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutamine; Humans; Lung Neoplasms; Mice; Mice, Nude; Phenylacetates; Piperidones; Tumor Cells, Cultured

2003
Managing social conflict in complementary and alternative medicine research: the case of antineoplastons.
    Integrative cancer therapies, 2004, Volume: 3, Issue:1

    Topics: Benzeneacetamides; Brain Neoplasms; Clinical Trials, Phase II as Topic; Communication; Complementary Therapies; Conflict of Interest; Documentation; Drug Combinations; Glutamine; Humans; Interprofessional Relations; Phenylacetates; Physician's Role; Piperidones; Power, Psychological; Problem Solving; Social Conditions; Trust

2004
Long-term survival and complete response of a patient with recurrent diffuse intrinsic brain stem glioblastoma multiforme.
    Integrative cancer therapies, 2004, Volume: 3, Issue:3

    Topics: Adult; Benzeneacetamides; Brain Stem Neoplasms; Disease-Free Survival; Drug Combinations; Glioblastoma; Glutamine; Health Status; Humans; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Survival Analysis; Time Factors; Treatment Outcome

2004
Rapid and flexible biochemical assays for evaluating 4'-phosphopantetheinyl transferase activity.
    The Biochemical journal, 2011, Jun-15, Volume: 436, Issue:3

    Topics: Apoenzymes; Bacillus subtilis; Bacterial Proteins; Carrier Proteins; Coumarins; Escherichia coli; Glutamine; Kinetics; Peptide Synthases; Piperidones; Pseudomonas aeruginosa; Substrate Specificity; Transferases (Other Substituted Phosphate Groups)

2011
Spectroscopic identification of cyclic imide b2-ions from peptides containing Gln and Asn residues.
    Journal of the American Society for Mass Spectrometry, 2013, Volume: 24, Issue:8

    Topics: Amides; Asparagine; Glutamine; Imides; Lasers; Models, Molecular; Nitrogen; Oxazolone; Oxygen; Peptides; Piperazines; Piperidones; Spectrophotometry, Infrared; Succinimides; Tandem Mass Spectrometry

2013
Comment to the paper "The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brain stem glioma" by Burzynski et al.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Female; Glioma; Glutamine; Humans; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons

2014
Comment to the paper: The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma : Stanislaw R. Burzynski, Tomasz J. Janicki, Gregory S.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Female; Glioma; Glutamine; Humans; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons

2014
Commentary on: "The response and survival of children with recurrent diffuse intrinsic pontine glioma based on phase II study of antineoplastons A10 and AS2-1 in patients with brainstem glioma." By Burzynski et al.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2014, Volume: 30, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzeneacetamides; Brain Stem Neoplasms; Female; Glioma; Glutamine; Humans; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Pons

2014
Complete response and long-term survival (>20 years) of a child with tectal glioma: a case report.
    Pediatric neurosurgery, 2015, Volume: 50, Issue:2

    Topics: Adolescent; Benzeneacetamides; Brain Neoplasms; Drug Combinations; Follow-Up Studies; Glioma; Glutamine; Humans; Male; Neoplasm Recurrence, Local; Phenylacetates; Piperidones; Treatment Outcome

2015
Efficient production of indigoidine in Escherichia coli.
    Journal of industrial microbiology & biotechnology, 2015, Volume: 42, Issue:8

    Topics: Ammonium Chloride; Ammonium Sulfate; Bacterial Proteins; Culture Media; Escherichia coli; Fermentation; Glutamate-Ammonia Ligase; Glutamine; Metabolic Engineering; Metalloendopeptidases; Nitrates; Phosphates; Piperidones; Potassium Compounds; Streptomyces

2015
A sensitive single-enzyme assay system using the non-ribosomal peptide synthetase BpsA for measurement of L-glutamine in biological samples.
    Scientific reports, 2017, 01-31, Volume: 7

    Topics: Bacterial Proteins; Biomarkers; Enzyme Assays; Gene Expression; Glutamine; Peptide Synthases; Piperidones; Reproducibility of Results

2017
Identification and characterization of lbpA, an indigoidine biosynthetic gene in the γ-butyrolactone signaling system of Streptomyces lavendulae FRI-5.
    Journal of bioscience and bioengineering, 2017, Volume: 124, Issue:4

    Topics: 4-Butyrolactone; Bacterial Proteins; Gene Expression Regulation, Bacterial; Glutamine; Multigene Family; Peptide Synthases; Piperidones; Signal Transduction; Streptomyces

2017
The indigoidine synthetase BpsA provides a colorimetric ATP assay that can be adapted to quantify the substrate preferences of other NRPS enzymes.
    Biotechnology letters, 2020, Volume: 42, Issue:12

    Topics: Adenosine Triphosphate; Biosensing Techniques; Colorimetry; Glutamine; Peptide Synthases; Piperidones

2020
Protein scaffold optimizes arrangement of constituent enzymes in indigoidine synthetic pathway to improve the pigment production.
    Applied microbiology and biotechnology, 2020, Volume: 104, Issue:24

    Topics: Bacterial Proteins; Glutamic Acid; Glutamine; Piperidones; Streptomyces

2020
Spontaneous protein-protein crosslinking at glutamine and glutamic acid residues in long-lived proteins.
    The Biochemical journal, 2021, 01-29, Volume: 478, Issue:2

    Topics: Cataract; Eye Proteins; Glutamic Acid; Glutamine; Humans; Lens, Crystalline; Lysine; Middle Aged; Piperidones; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Young Adult

2021