glutamine and 2-keto-4-methylvalerate

glutamine has been researched along with 2-keto-4-methylvalerate in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199012 (35.29)18.7374
1990's9 (26.47)18.2507
2000's9 (26.47)29.6817
2010's4 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rideau, N; Simon, J2
Gerok, W; Häussinger, D; Lang, F; Morimoto, Y; Stoll, B1
Lenzen, S; Panten, U; Schmidt, W1
Kagawa, S; Matsuoka, A; Nakao, K; Wakabayashi, S1
Gylfe, E1
Brunengraber, H; David, F; Garneau, M; Huot, S; Marsolais, C1
Brunstedt, J; Hellerström, C; Welsh, M1
Manning, CD; Matschinsky, FM; Meglasson, MD; Najafi, H1
Andersson, A; Hellerström, C; Welsh, M1
Hutton, JC; Malaisse, WJ; Sener, A1
Christophe, J; Hutton, JC; Malaisse, WJ; Malaisse-Legae, F; Sener, A1
Malaisse, WJ; Malaisse-Lagae, F; Sener, A2
Carbonnel, F; Darmaun, D; Desjeux, JF; Koziet, J; Messing, B; Rigal, O; Rimbert, A; Rongier, M; Thuillier, F1
Brillon, DJ; Campbell, RG; Matthews, DE; Zheng, B1
Daikhin, Y; Nissim, I; Pleasure, D; Stern, J; Yudkoff, M1
Thompson, JR; Zhou, X1
Jijakli, H; Kadiata, MM; Kirk, O; Malaisse, WJ; Sener, A1
Baab, PJ; Collins, RM; Huang, Y; Tildon, JT; Zielke, CL; Zielke, HR1
Clark, A; de Koning, EJ; MacArthur, DL; Morris, JF; Verbeek, JS1
Bouteloup-Demange, C; Claeyssens, S; Dechelotte, P; Lavoinne, A; Lerebours, E; Maillot, C1
Hulsewé, KW; Soeters, PB; van Acker, BA; von Meyenfeldt, MF; Wagenmakers, AJ1
Börger, J; Brabant, G; Lange, S; Schöfl, C; von zur Mühlen, A1
Dura, E; Jijakli, H; Malaisse, WJ; Ramirez, R; Sener, A; Zhang, HX1
Buettger, C; Gao, Z; Li, G; Matschinsky, FM; Najafi, H; Sukumvanich, SS; Wolf, BA; Wong, RK; Young, RA1
Agascioglu, E; Giroix, MH; Malaisse, WJ; Sener, A1
Bergsten, P; Fernández-Pascual, S; Hernández-Fisac, I; Martín del Río, R; Ortsäter, H; Pizarro-Delgado, J; Tamarit-Rodriguez, J1
Carpentier, YA; Chardigny, JM; Courtois, P; Louchami, K; Malaisse, WJ; Oguzhan, B; Portois, L; Sener, A; Zhang, Y1
Fex, M; Ling, C; Mulder, H; Nitert, MD; Sundler, F; Wierup, N1
Goshorn, S; Jetton, TL; Lynch, CJ; She, P; Zhou, Y1
Dahanayaka, S; Dai, Z; Feng, D; Lei, J; Li, X; Wang, J; Wu, G; Wu, Z; Yao, K; Zhang, Y1
Gurgul-Convey, E; Kaminski, MT; Lenzen, S1
Asbury, CL; Deng, Y; Hille, B; Jung, SR; Koh, DS; Kushmerick, C1

Trials

1 trial(s) available for glutamine and 2-keto-4-methylvalerate

ArticleYear
Response of glutamine metabolism to glutamine-supplemented parenteral nutrition.
    The American journal of clinical nutrition, 2000, Volume: 72, Issue:3

    Topics: Aged; Glutamine; Humans; Keto Acids; Kinetics; Middle Aged; Parenteral Nutrition, Total

2000

Other Studies

33 other study(ies) available for glutamine and 2-keto-4-methylvalerate

ArticleYear
Specificity of the permissive effect of D-glucose on insulin release in chicken pancreas.
    Comparative biochemistry and physiology. Comparative physiology, 1992, Volume: 103, Issue:4

    Topics: 3-O-Methylglucose; Animals; Asparagine; Chickens; Glucose; Glutamine; Glyceraldehyde; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Mannose; Methylglucosides; Perfusion

1992
Anisoosmostic liver perfusion: redox shifts and modulation of alpha-ketoisocaproate and glycine metabolism.
    Biological chemistry Hoppe-Seyler, 1992, Volume: 373, Issue:8

    Topics: Animals; Cell Size; Glucagon; Glutamine; Glycine; Keto Acids; Ketones; Liver; Male; Mitochondria, Liver; NAD; Osmolar Concentration; Osmosis; Oxidation-Reduction; Perfusion; Rats; Rats, Wistar

1992
L-leucine or its keto acid potentiate but do not initiate insulin release in chicken.
    The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine; Chickens; Drug Synergism; Glucose; Glutamine; Insulin; Insulin Secretion; Keto Acids; Leucine; Male; Pancreas; Potassium

1989
Transamination of neutral amino acids and 2-keto acids in pancreatic B-cell mitochondria.
    The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23

    Topics: Animals; Caproates; Cytoplasm; Glutamates; Glutamic Acid; Glutamine; Hemiterpenes; Islets of Langerhans; Keto Acids; Kinetics; Leucine; Mice; Mice, Obese; Mitochondria; Transaminases; Valine

1985
Maintenance of pancreatic endocrine cells of the neonatal rat: VII. The effect of 3-amino-3-deoxyglucose on insulin secretion from perifused B cells.
    Endocrinologia japonica, 1986, Volume: 33, Issue:5

    Topics: Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Glucosamine; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Rats; Rats, Inbred Strains

1986
Nutrient secretagogues induce bimodal early changes in cytoplasmic calcium of insulin-releasing ob/ob mouse beta-cells.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Amino Acids; Amino Acids, Cyclic; Animals; Arginine; Calcium; Cytoplasm; Dose-Response Relationship, Drug; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Mice; Mice, Obese; Obesity

1988
Compartmentation of 14CO2 in the perfused rat liver.
    The Journal of biological chemistry, 1987, Feb-25, Volume: 262, Issue:6

    Topics: Acetazolamide; Acetoacetates; Animals; Carbon Dioxide; Cell Compartmentation; Formates; Glutamine; Keto Acids; Liver; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Urea

1987
Effects of D-glucose, L-leucine, and 2-ketoisocaproate on insulin mRNA levels in mouse pancreatic islets.
    Diabetes, 1986, Volume: 35, Issue:2

    Topics: Animals; Glucose; Glutamine; Insulin; Islets of Langerhans; Keto Acids; Leucine; Male; Mice; Mice, Inbred Strains; Oxygen Consumption; RNA, Messenger

1986
Fuel-stimulated insulin secretion by clonal hamster beta-cell line HIT T-15.
    Diabetes, 1987, Volume: 36, Issue:4

    Topics: 3-O-Methylglucose; Animals; Cell Line; Cricetinae; Dihydroxyacetone; Energy Metabolism; Glucose; Glutamine; Hemiterpenes; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Lactates; Lactic Acid; Methylglucosides

1987
Respiration and insulin release in mouse pancreatic islets. Effects of L-leucine and 2-ketoisocaproate in combination with D-glucose and L-glutamine.
    Biochimica et biophysica acta, 1982, Oct-11, Volume: 721, Issue:2

    Topics: Animals; Caproates; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Leucine; Male; Mice; Mice, Inbred Strains; Oxygen Consumption

1982
The stimulus-secretion coupling of amino acid-induced insulin release. Synergistic effects of L-glutamine and 2-keto acids upon insulin secretion.
    Biochimica et biophysica acta, 1981, Sep-18, Volume: 677, Issue:1

    Topics: Animals; Caproates; Drug Synergism; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Rats; Valine

1981
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic interaction of L-glutamine and 2-ketoisocaproate in pancreatic islets.
    Biochimica et biophysica acta, 1981, Sep-18, Volume: 677, Issue:1

    Topics: Animals; Drug Synergism; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; NAD; NADP; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Transaminases

1981
Noncarbohydrate nutrients protect against alloxan-induced inhibition of insulin release.
    Endocrinology, 1982, Volume: 110, Issue:6

    Topics: Alloxan; Amino Acids; Animals; Glucose; Glutamine; Insulin; Islets of Langerhans; Keto Acids; Leucine; NAD; NADP; Rats; Time Factors

1982
The stimulus-secretion coupling of glucose-induced insulin release: effect of aminooxyacetate upon nutrient-stimulated insulin secretion.
    Endocrinology, 1982, Volume: 111, Issue:2

    Topics: Acetates; Aminooxyacetic Acid; Animals; Glucose; Glutamine; Insulin; Islets of Langerhans; Keto Acids; Leucine; Malates; Pyruvates; Pyruvic Acid; Rats

1982
Energy and protein metabolism in malnutrition due to nonneoplastic gastrointestinal diseases.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:9

    Topics: Body Mass Index; Body Weight; C-Reactive Protein; Calorimetry, Indirect; Energy Metabolism; Gastrointestinal Diseases; Glutamine; Humans; Keto Acids; Leucine; Nutrition Disorders; Proteins; Retinol-Binding Proteins; Serum Albumin; Skinfold Thickness

1995
Effect of cortisol on energy expenditure and amino acid metabolism in humans.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 1

    Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glutamine; Growth Hormone; Humans; Hydrocortisone; Insulin; Keto Acids; Kinetics; Leucine; Male; Phenylalanine

1995
Inhibition of astrocyte glutamine production by alpha-ketoisocaproic acid.
    Journal of neurochemistry, 1994, Volume: 63, Issue:4

    Topics: Ammonium Chloride; Animals; Animals, Newborn; Astrocytes; Caproates; Cells, Cultured; Glutamate-Ammonia Ligase; Glutaminase; Glutamine; Keto Acids; Kinetics; L-Lactate Dehydrogenase; Nitrogen Isotopes; Prosencephalon; Rats; Rats, Sprague-Dawley

1994
Regulation of glutamate dehydrogenase by branched-chain amino acids in skeletal muscle from rats and chicks.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:7

    Topics: Acidosis; Amino Acids, Branched-Chain; Ammonium Chloride; Animals; Chickens; Glutamate Dehydrogenase; Glutamine; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Mitochondria, Muscle; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Valine

1996
Stimulation of insulin release by alpha-D-glucose pentaacetate.
    Biochemical and biophysical research communications, 1997, Feb-13, Volume: 231, Issue:2

    Topics: 3-O-Methylglucose; Animals; Drug Interactions; Female; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Rats; Rats, Wistar

1997
Effect of alpha-ketoisocaproate and leucine on the in vivo oxidation of glutamate and glutamine in the rat brain.
    Neurochemical research, 1997, Volume: 22, Issue:9

    Topics: Animals; Brain; Caproates; Glutamic Acid; Glutamine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Microdialysis; Oxidation-Reduction; Rats

1997
Amyloid fibril formation is progressive and correlates with beta-cell secretion in transgenic mouse isolated islets.
    Diabetologia, 1999, Volume: 42, Issue:10

    Topics: Amyloid; Animals; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Extracellular Space; Female; Glucose; Glutamine; Humans; Hypoglycemic Agents; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Keto Acids; Leucine; Male; Mice; Mice, Transgenic; Time Factors; Tolbutamide

1999
Effects of enteral glutamine on gut mucosal protein synthesis in healthy humans receiving glucocorticoids.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 278, Issue:5

    Topics: Administration, Oral; Adult; Carbon Isotopes; Duodenum; Enteral Nutrition; Female; Glucocorticoids; Glutamine; Humans; Infusions, Intravenous; Intestinal Absorption; Intestinal Mucosa; Keto Acids; Leucine; Male; Phenylalanine; Prednisolone; Protein Biosynthesis; Tritium

2000
Energetic requirement of carbachol-induced Ca2+ signaling in single mouse beta-cells.
    Endocrinology, 2000, Volume: 141, Issue:11

    Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Culture Media; Energy Metabolism; Female; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Mice; NAD; Pyruvates; Signal Transduction; Type C Phospholipases

2000
Effects of cytochalasin B and D upon insulin release and pancreatic islet cell metabolism.
    International journal of molecular medicine, 2002, Volume: 9, Issue:2

    Topics: 3-O-Methylglucose; Amino Acids; Animals; Carbon Dioxide; Colforsin; Cytochalasin B; Cytochalasin D; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Radioisotopes; Rats; Water

2002
Distinguishing features of leucine and alpha-ketoisocaproate sensing in pancreatic beta-cells.
    Endocrinology, 2003, Volume: 144, Issue:5

    Topics: Aminooxyacetic Acid; Animals; Calcium; Cell Extracts; Cell Line; Chemoreceptor Cells; Culture Techniques; Cytosol; Dose-Response Relationship, Drug; Glucose; Glutamate Dehydrogenase; Glutamine; Insulin; Insulin Secretion; Intracellular Membranes; Islets of Langerhans; Keto Acids; Leucine; Mice; Mice, Inbred Strains; Nucleotides; Osmolar Concentration; Oxidation-Reduction; Rats; Rats, Wistar

2003
Adenine nucleotide pattern in rat pancreatic islets exposed to nutrient secretagogues.
    Endocrine, 2006, Volume: 29, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Female; Galactose; Glucose; Glutamine; Glyceraldehyde; Islets of Langerhans; Keto Acids; Lactic Acid; Leucine; Mannose; Nutritional Physiological Phenomena; Pyruvic Acid; Rats; Rats, Wistar

2006
Oxo-4-methylpentanoic acid directs the metabolism of GABA into the Krebs cycle in rat pancreatic islets.
    The Biochemical journal, 2006, Nov-15, Volume: 400, Issue:1

    Topics: Aldehyde Oxidoreductases; Amino Acids; Animals; Cerebellum; Citric Acid Cycle; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Glucose; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Male; Oxidation-Reduction; Oxygen; Rats; Rats, Wistar; Succinate-Semialdehyde Dehydrogenase; Time Factors; Transaminases

2006
Pancreatic islet function in omega3 fatty acid-depleted rats: Glucose metabolism and nutrient-stimulated insulin release.
    Endocrine, 2006, Volume: 29, Issue:3

    Topics: Animals; Blood Glucose; Carbon Dioxide; Diet; Dietary Fats; Fats; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Female; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Leucine; Liver; Male; Phospholipids; Rats; Triglycerides; Verapamil

2006
Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.
    Diabetologia, 2007, Volume: 50, Issue:1

    Topics: Adaptation, Physiological; Animals; Blood Glucose; Body Weight; Dietary Fats; Female; Glutamine; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Keto Acids; Mice; Mice, Inbred C57BL; Mitochondria; Palmitates; Succinates

2007
Transamination is required for {alpha}-ketoisocaproate but not leucine to stimulate insulin secretion.
    The Journal of biological chemistry, 2010, Oct-29, Volume: 285, Issue:44

    Topics: Adenosine Triphosphate; Animals; Female; Glucose; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Ketoglutaric Acids; Leucine; Mice; Mice, Transgenic; Mitochondria; Oxygen; Transaminases

2010
Regulation of leucine catabolism by metabolic fuels in mammary epithelial cells.
    Amino acids, 2012, Volume: 43, Issue:5

    Topics: 3-Hydroxybutyric Acid; 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Blotting, Western; Carbon Radioisotopes; Cattle; Cells, Cultured; Culture Media; Decarboxylation; Epithelial Cells; Female; Gene Expression; Glucose; Glutamine; Keto Acids; Leucine; Mammary Glands, Animal; Oleic Acid; Phosphorylation; Transaminases

2012
Physiological characterization of the human EndoC-βH1 β-cell line.
    Biochemical and biophysical research communications, 2015, Aug-14, Volume: 464, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Diphosphate; Adenosine Triphosphate; Biological Transport; Calcium Channels; Cell Line; Colforsin; Founder Effect; Gene Expression; Glucokinase; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 2; Glutamine; Glyburide; Humans; Insulin; Insulin-Secreting Cells; Keto Acids; Leucine; Mannoheptulose; Phosphorylation; Potassium Channels, Inwardly Rectifying

2015
Minimizing ATP depletion by oxygen scavengers for single-molecule fluorescence imaging in live cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 06-19, Volume: 115, Issue:25

    Topics: Adenosine Triphosphate; Carbocyanines; Cell Line; Flavin-Adenine Dinucleotide; Fluorescence; Fluorescent Dyes; Glucose Oxidase; Glutamine; HEK293 Cells; Humans; Keto Acids; Microscopy, Fluorescence; Mitochondria; NAD; Oxygen; Phosphatidylinositol 4,5-Diphosphate; Photobleaching; Receptor, PAR-2

2018