glutamic acid has been researched along with tryptophan in 204 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (6.37) | 18.7374 |
| 1990's | 44 (21.57) | 18.2507 |
| 2000's | 82 (40.20) | 29.6817 |
| 2010's | 45 (22.06) | 24.3611 |
| 2020's | 20 (9.80) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Anthony, A; Augustyn, E; Bauer, J; Campbell, J; Chien, HC; Colas, C; Finke, K; Flint, A; Fotiadis, D; Giacomini, KM; Hall, C; Hansen, L; Heeren, N; Hernandez, C; Schlessinger, A; Springer, S; Stoner, L; Thomas, AA; Venteicher, B; Zur, AA | 1 |
| Brzović, PS; Dunn, MF; Kayastha, AM; Miles, EW | 1 |
| Butterworth, RF; Szerb, JC | 1 |
| Nomura, Y; Tohda, M; Urushihara, H | 1 |
| Doi, M; Inoue, M; Ishida, T; Iyo, H; Morioka, H; Nishikawa, S; Tanaka, T; Ueda, H; Uesugi, S | 1 |
| Engelhard, M; Hess, B; Kreutz, W; Metz, G; Oesterhelt, D; Siebert, F; Soppa, J | 1 |
| Hurlburt, BK; Yanofsky, C | 1 |
| Hosono, A; Ohta, Y; Zhang, XB | 1 |
| Capiau, C; Feron, C; Locht, C | 1 |
| Bell, EF; Filer, LJ; Stegink, LD; Tephly, TR; Ziegler, EE | 1 |
| Meessen, S; Oesterhelt, D; Otomo, J; Soppa, J; Straub, J; Tittor, J | 1 |
| Carroll, J; Killen, HM | 1 |
| Ahl, PL; Khorana, HG; Mogi, T; Rothschild, KJ; Stern, LJ | 1 |
| Mitchell, CK; Redburn, DA | 1 |
| Jigami, Y; Morikawa, M; Muraki, M; Tanaka, H | 1 |
| Chen, CH; Tabita, FR; Van Baalen, C | 1 |
| Claus, D; Kim, JS; Kornhuber, HH; Schmid-Burgk, W | 1 |
| Engerman, RL; Kern, TS | 1 |
| Glass, JD; Rea, MA; Selim, M; Srkalovic, G | 1 |
| Ishizaki, T; Morii, N; Narumiya, S; Nemoto, Y; Saito, Y; Watanabe, N | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Francois-Bellan, AM; Giraud, P; Hery, F; Hery, M | 1 |
| Delcamp, TJ; Freisheim, JH; Li, H; Meiering, EM; Wagner, G | 1 |
| Borriss, R; Hahn, M; Heinemann, U; Olsen, O; Politz, O | 1 |
| Ladant, D | 1 |
| Haser, R; Kadziola, A; Svensson, B; Søgaard, M | 1 |
| Douglas, FL; Melethil, S; Rakhit, A; Tang, JP; Xu, ZQ | 1 |
| Hartley, BS; Loviny-Anderton, T; Rangarajan, M; Siddiqui, KS | 1 |
| Matsumoto, H; Ohnishi, H; Ohta, T; Sakai, H | 1 |
| Goldberg, EB; Grinius, LL | 1 |
| Ueda, T; Winter, HC | 1 |
| Fuchs, JA; Hanson, C; Li, H; Thomas, GJ; Woodward, C | 1 |
| Sipos, L; von Heijne, G | 1 |
| Berelowitz, M; Bruno, JF; Song, J; Xu, Y | 1 |
| Lee, S; Naime, D; Okubo, Y; Redman, C; Reid, M; Sistonen, P; Son, S; Wu, X | 1 |
| Clausen, IG; Holmquist, M; Hult, K; Martinelle, M; Patkar, S; Svendsen, A | 1 |
| Fisher, HF; Maniscalco, SJ; Saha, SK | 1 |
| Bellet, PS; Harris, BV; Keilson, LM; Simbartl, LA; Sprecher, DL; Stein, EA | 1 |
| Goda, S; Harata, K; Muraki, M; Nagahora, H | 1 |
| Allen, JP; Breton, J; Nabedryk, E; Williams, JC | 1 |
| Fersht, AR; Frisch, C; Schreiber, G | 1 |
| Davidson, VL; Graichen, ME; Hosler, JP; Jones, LH; Mathews, FS | 1 |
| Chaudhri, G; Hunt, NH; Moore, DE; Sanni, LA; Stocker, R; Tattam, BN; Thomas, SR | 1 |
| Baig, SM; Bednar, I; Halawa, A; Parvez, SH; Qureshi, GA | 1 |
| Doctor, BP; Frazier, DS; Kovach, IM; Lockridge, O; Maxwell, DM; Saxena, A; Viragh, C | 1 |
| Blodig, W; Doyle, WA; Piontek, K; Smith, AT; Veitch, NC | 1 |
| Adachi, K; Harrington, DJ; Royer, WE | 1 |
| Kang, HJ; Lee, ES; Lee, JH; Lee, S; Park, KB; Son, IY; Steinert, PM; Yang, JM; Yeo, UC | 1 |
| Bonn, G; Fiechtner, B; Glossmann, H; Huck, CW; Moebius, FF; Soellner, KE | 1 |
| Josse, D; Lockridge, O; Masson, P; Renault, F; Rochu, D; Schopfer, LM; Xie, W | 1 |
| Arrendondo-Vega, FX; Buckley, R; Conley, ME; El Dahr, J; Hershfield, MS; Notarangelo, LD; Roifman, C; Santisteban, I | 1 |
| Brady, K; Denton, G; Matteis, CI; Missailidis, S; Murray, A; Price, MR; Searle, MS; Spencer, DI; Tendler, SJ | 1 |
| Kirley, TL; Lewis Carl, SA; Smith, TM | 1 |
| Arata, Y; Ito, S; Kawaminami, S; Shimada, I; Takahashi, H | 1 |
| Bibikova, M; Breton, J; Nabedryk, E; Oesterhelt, D | 1 |
| Belokrylov, GA; Sorochinskaya, EI | 1 |
| Aoudia, M; Guliaev, AB; Leontis, NB; Rodgers, MA | 1 |
| Imoto, T; Ishibashi, R; Masumoto, K; So, T; Ueda, T | 1 |
| Cavieres, M; dal Borgo, P; Español, T; Estivill, X; Fillat, C; Oset, M; Volpini, V | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Chandra, M; Pearlstone, JR; Smillie, LB; Sorenson, MM | 1 |
| Chen, X; Luo, Q; Ni, J; Wang, H; Zhang, Q; Zou, H | 1 |
| Hagedorn, CH; Hodel, AE; Hodel, MR; Hsu, PC; Taylor, LJ; Thomas, JW | 1 |
| Dittel, BN; Janeway, CA | 1 |
| Pham, HT; Ruediger, R; Walter, G | 1 |
| Antignani, A; Cubellis, MV; D'Alessio, G; Naddeo, M; Russo, A | 1 |
| Liu, Y; Schepartz, A | 1 |
| Kim, C; Mills, SE; Nguyen-Huu, X; Spraggon, G; Yanofsky, C; Yee, MC | 1 |
| Carlsson, M; Groop, LC; Hedenbro, J; Orho-Melander, M | 1 |
| Bigotti, MG; Brunori, M; Cutruzzolà, F; Gianni, S; Travaglini-Allocatelli, C | 1 |
| Baraldi, M; Cannazza, G; Zanoli, P | 1 |
| Adachi, O; Devreese, B; Duine, JA; Hacisalihoglu, A; Iwabuki, H; Jongejan, JA; Kim, JK; Kuroda, S; Okajima, T; Tanizawa, K; Van Beeumen, J; Vandenberghe, I | 1 |
| Mitra, R; Sainis, KB; Suseelan, KN | 1 |
| Christie, GR; Hajduch, E; Hundal, HS; Proud, CG; Taylor, PM | 1 |
| Beyermann, M; Blomenröhr, M; Bogerd, J; Hund, E; Kühne, R; Leurs, R; ter Laak, T | 1 |
| Aquilina, A; Bergelson, JM; Farndale, RW; Humphries, MJ; Korda, M; Tuckwell, D | 1 |
| Palecz, B | 1 |
| Bohác, M; Damborský, J; Koca, J; Monincová, M; Nagata, Y; Prokop, M; Prokop, Z; Tsuda, M | 1 |
| Allison, WS; Bandyopadhyay, S; Huynh, HG; Ren, H; Valder, CR | 1 |
| Bernstein, KE; Gernert, K; Ma, X; Sandberg, EM; Sayeski, PP; VonDerLinden, D | 1 |
| Baik, HS; Cho, HS; Choi, JW; Lee, SY; Paik, SY; Park, HS; Park, YC; Ra, KS; Yun, JW | 1 |
| Abend, J; Dewhurst, S; Koide, A; Koide, S; Miller, M; Richards, J | 1 |
| Watanabe, Y | 2 |
| Morokuma, K; Zuilhof, H | 1 |
| Chae, KS; Han, Y; Kim, H; Park, S; Song, S; Uhm, TB | 1 |
| FEREN, CJ; HEDRICK, LR | 1 |
| Park, C; Shin, D | 1 |
| Baldwin, J; Bollinger, JM; Huynh, BH; Krebs, C; Riggs-Gelasco, P; Saleh, L; Stelling, M | 1 |
| De Lorenzo, C; Del Carmen Polo, M; Iglesias, MT; Martín-Alvarez, PJ; Pueyo, E | 1 |
| Klebe, G; Rauh, D; Stubbs, MT | 1 |
| Chan, NK; Chew, SF; Hiong, KC; Ip, YK; Loong, AM; Tam, WL | 1 |
| HATA, H | 1 |
| de Jong, AS; Glaudemans, DH; Melchers, WJ; van Kuppeveld, FJ; Willems, PH | 1 |
| Bachmann, C; Boulat, O; Braissant, O; Henry, H; Villard, AM | 1 |
| Britton, J; Broadfield, E; Fogarty, A; Lawson, N; Lewis, S | 1 |
| Castro, C; Collinsová, M; Evans, JC; Garrow, TA; Gratson, AA; Jiracek, J; Ludwig, ML | 1 |
| Benevides, JM; Bondre, P; Duda, RL; Hendrix, RW; Thomas, GJ | 1 |
| Du, GG; Guo, X; Khanna, VK; MacLennan, DH | 1 |
| Beauregard, M; Claveau, S; Gagnon, MC; Sasseville, M | 1 |
| Kim, YW; Lee, SS; Warren, RA; Withers, SG | 1 |
| Gittis, AG; Lattman, EE; Leila Reynald, R; Nguyen, DM | 1 |
| Gordillo, R; Guan, L; Kaback, HR; Vázquez-Ibar, JL; Verner, G; Weinglass, AB | 1 |
| Fei, J; Guo, L; Schwarz, W; Vasilets, LA; Zhu, Y | 1 |
| Corbett, K; Davis, BG; Fordham-Skelton, AP; Gatehouse, JA; Hancock, SM | 1 |
| Finazzi, G; Hippler, M; Sommer, F | 1 |
| Kajikawa, H; Kurihara, M; Mitsumori, M; Tajima, K | 1 |
| Fekkes, D; Hoekstra, R; Loonen, AJ; Pepplinkhuizen, L; Tuinier, S; Verhoeven, WM | 1 |
| Hausmann, S; Shuman, S | 1 |
| Kannan, N; Neuwald, AF | 1 |
| Egebjerg, J; Gajhede, M; Geballe, MT; Holm, MM; Kastrup, JS; Naur, P; Traynelis, SF; Vestergaard, B | 1 |
| Beachy, PA; Fuse, N; Maity, T | 1 |
| Huuhka, M; Keränen, T; Leinonen, E; Oja, SS; Palmio, J; Peltola, J; Saransaari, P; Suhonen, J | 1 |
| Li, LY; Rah, JC; Rhee, JS; Rizo, J; Rosenmund, C; Shin, OH; Südhof, TC | 1 |
| Champeil, P; Falson, P; Jaxel, C; le Maire, M; Lenoir, G; Picard, M | 1 |
| Gouda, H; Hirono, S; Iwatsuki, M; Omura, S; Tomoda, H; Uchida, R | 1 |
| Estabrook, RA; Reich, N | 1 |
| Mukai, M; Tischkau, SA | 1 |
| Chan, SS; Copeland, WC; Longley, MJ | 1 |
| Bartolotti, LJ; Burns, CS; Kenward, AG | 1 |
| Dai, XP; Li, HH; Liu, J; Liu, ZQ; Mo, W; Tan, YM; Yang, TL; Zeng, H; Zhang, GG; Zhou, HH | 1 |
| Gbaguidi, B; Hakizimana, P; Ruysschaert, JM; Vandenbussche, G | 1 |
| Engel, PC; Hamza, MA; Martin, SR | 1 |
| Cheng, CY; Kim, C; Saldanha, SA; Taylor, SS | 1 |
| Cheng, KC; Connor, JR; Goodman, SI; Housman, C; Jacobs, RE; LaNoue, K; Lazovic, J; O'Callaghan, JP; Simpson, I; Woontner, M; Zinnanti, WJ | 1 |
| Allhorn, M; Collin, M; Olsén, A | 1 |
| Dong, C; Ernyei, AJ; Flecks, S; Naismith, JH; Patallo, EP; Schneider, A; Seifert, G; van Pée, KH; Zhu, X | 1 |
| Baran, H; Kepplinger, B | 1 |
| Aquilina, JA; Carver, JA; Morris, AM; Treweek, TM; Walker, MJ | 1 |
| Hu, F; Li, HX; Wei, ZG; Wu, JL; Zhao, HY | 1 |
| Galocha, B; García-Medel, N; Gómez, P; López de Castro, JA; Mavian, C | 1 |
| Schuldiner, S | 1 |
| Aikoh, H; Shibahara, T; Yamato, M | 1 |
| Betzel, C; Kaur, P; Perbandt, M; Sharma, P; Sharma, S; Singh, N; Singh, TP; Sinha, M; Srinivasan, A | 1 |
| Fülöp, F; Klivényi, P; Toldi, J; Vámos, E; Vécsei, L; Zádori, D | 1 |
| Riemen, AJ; Waters, ML | 1 |
| Cymer, F; Schneider, D | 1 |
| Appelhans, D; Müller, M; Ouyang, W; Voit, B | 1 |
| Dabrowska, M; Groenendyk, J; Michalak, M | 1 |
| Chen, J; Ghosh, K; Gibb, B; Gupta, K; Sharp, R; Van Duyne, GD | 1 |
| Barre, A; Lasanajak, Y; Proost, P; Rougé, P; Schouppe, D; Smith, DF; Van Damme, EJ | 1 |
| Culka, A; Edwards, HG; Jehlička, J | 1 |
| Davidson, VL; Goblirsch, BR; Wilmot, CM; Yukl, ET | 1 |
| Bernstein, HG; Bielau, H; Bogerts, B; Brisch, R; Gos, T; Guillemin, GJ; Mawrin, C; Meyer zu Schwabedissen, L; Myint, AM; Sarnyai, Z; Steiner, J; Walter, M | 1 |
| Bhowmik, AD; Chaudhuri, K; Mukherjee, S; Mukhopadhyay, K; Ray, JG; Roychoudhury, P | 1 |
| Dinaj, A; Ijzerman, AP; Peeters, MC; Vriend, G; Vroling, B; Wisse, LE | 1 |
| Amachawadi, RG; Elwakeel, EA; Nagaraja, TG; Nasser, ME; Nour, AM; Titgemeyer, EC | 1 |
| Barboni, L; Graham, D; Liao, Z; Nzowa, LK; Tapondjou, LA; Teponno, RB; Verotta, L; Zink, MC | 1 |
| Boehr, DD; Yezdimer, EM; Zaccardi, MJ | 1 |
| Abu Tarboush, N; Davidson, VL; Feng, M; Shin, S; Wilmot, CM; Yukl, ET | 1 |
| Chaen, H; Fukuda, S; Fushinobu, S; Nishimoto, T; Okada, S; Wakagi, T; Watanabe, H; Yamamoto, T | 1 |
| Bahret, E; Mueller, E; Vajda, J | 1 |
| Majláth, Z; Vécsei, L | 1 |
| Campbell, C; Foshag, D; Pawelek, PD | 1 |
| Cintra, AC; Martins, NM; Sampaio, SV; Santos, AC; Santos, NA; Sartim, MA | 1 |
| Bystrowska, B; Gaweł, M; Holst, B; Librowski, T; Młyniec, K; Reczyński, W | 1 |
| Delangle, P; Laporte, FA; Lebrun, C; Oros, S; Sisommay, N; Starck, M | 1 |
| Deng, Z; Lei, G; Li, Y; Luo, W; Ren, W; Wu, G; Xiao, W; Zeng, C | 1 |
| De Picker, L; Dedeurwaerdere, S; Kosten, L; Staelens, S; Stroobants, S; Thomae, D; Van Eetveldt, A; Verhaeghe, J; Verkerk, R; Wyffels, L | 1 |
| Can, A; Chiappelli, J; Du, X; Fuchs, D; Hong, LE; Kochunov, P; Lowry, CA; Postolache, TT; Rowland, LM; Savransky, A; Shukla, DK; Tagamets, M; Wijtenburg, SA | 1 |
| Schwarcz, R | 1 |
| Adochite, RC; Andreev, OA; El-Sayed, NS; Golijanin, J; Moshnikova, A; Parang, K; Reshetnyak, YK; Slaybaugh, G; Tiwari, RK; Weerakkody, D | 1 |
| Bi, K; Chen, X; Gu, L; Hou, C; Shi, H; Xing, H; Zhang, M; Zhao, L | 1 |
| Chen, L; Zeng, AP | 1 |
| Bottrel, N; Corum, DG; Drevets, WC; Fiehn, O; Kaddurah-Daouk, R; Motsinger-Reif, A; Rotroff, DM; Salvadore, G; Singh, J | 1 |
| Baker, GB; Li, XM; Rauw, G; Wang, WQ; Zheng, HF | 1 |
| Dwyer, DS; Peoples, RW; Ren, H; Wu, M; Zhao, Y | 1 |
| Choi, MH; Chung, BC; Hong, J; Lee, W; Park, NH; Shin, HJ | 1 |
| Anderton, RS; Blacker, DJ; Clark, VW; Cross, JL; Edwards, AB; Knuckey, NW; Meloni, BP; Milani, D | 1 |
| Parasram, K | 1 |
| Bermudez, I; Csanova, A; Franklin, M; Hlavacova, N; Jezova, D; Li, Y; Sanchez, C | 1 |
| Caso, JR; García-Bueno, B; Leza, JC; Madrigal, JLM; Martín-Hernández, D; Tendilla-Beltrán, H | 1 |
| Chang, CW; Chiang, CW; Jackson, MB | 1 |
| Baghdoyan, HA; Bellesi, M; Bourdon, AK; Campagna, SR; Cirelli, C; Lydic, R; Marshall, W; Serra, PA; Spano, GM; Tononi, G | 1 |
| Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E | 1 |
| Chen, N; Du, L; Xu, Q; Zhang, Z | 1 |
| Kuusisto, J; Laakso, M; Smith, U; Stancáková, A; Vangipurapu, J | 1 |
| Han, XM; Lu, YN; Qin, YJ; Rang, Y; Wang, NX; Zhai, XJ; Zhang, XL; Zhu, Y | 1 |
| Jin, X; Kim, JK; Kwon, HN; Lee, SK; Park, S; Shin, C; Yoon, DW; Yun, CH | 1 |
| Besseling, P; Cho, M; Goldstein, JM; Lee, KH; Lee, RT; Lewandowski, JP; Messemer, KA; Mills, MJ; Valido, A; Wagers, AJ; Walker, RG; Wattrus, SJ | 1 |
| Ansari, MZ; Swaminathan, R | 1 |
| Cseh, EK; Klivényi, P; Körtési, T; Nánási, N; Párdutz, Á; Polyák, H; Tajti, J; Vécsei, L; Veres, G; Zádori, D | 1 |
| Ayala-Rodríguez, JÁ; de la Cruz, HR; Guevara-García, ÁA; López-Bucio, J; López-Bucio, JS; Pelagio-Flores, R; Ravelo-Ortega, G; Ruiz-Herrera, LF | 1 |
| Corsi-Zuelli, F; da Roza, DL; Del-Ben, CM; Deminice, R; Fachim, HA; Jordão, AA; Loureiro, CM; Louzada-Junior, P; Menezes, PR; Shuhama, R; Simões-Ambrosio, LMC | 1 |
| Fu, J; Han, P; Ma, SR; Pan, LB; Peng, R; Wang, Y; Xu, H; Yu, H; Yu, JB; Zhang, ZW | 1 |
| Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A | 1 |
| Alvarenga, AC; Appel, RM; Arima, EC; Ayache, R; Budib, MA; D'Amora, P; Diaz, RS; Evans, SS; Júnior, SS; Martins, WG; Nagourney, RA; Palma, AM; Pontes, HBD; Salzgeber, MB; Silva, FC; Silva, IDCG; Silva, NLF; Silva, RMS | 1 |
| Chen, L; Gao, M; Guan, F; He, K; Li, J; Liu, M; Lv, Y; Shi, T; Zhang, H; Zhang, M; Zhao, J; Zhao, Y | 1 |
| Bai, M; Chen, C; Chen, X; Chen, Z; Cheng, K; Fang, L; He, Y; Lan, T; Li, Y; Tian, Y; Wang, Y; Wu, Z; Xie, P; Xu, X; Yang, D; Yu, H; Zhao, L | 1 |
| Cai, H; Cao, T; Chen, Q; Jiao, S; Wang, L; Wu, X; Yang, C; Yang, D; Yang, P; Zeng, C; Zhang, S; Zhu, Z | 1 |
| Emami Aleagha, MS; Mohammadi, P; Pashaei, S; Yarani, R | 1 |
| Chai, X; Li, Z; Liu, F; Sun, P; Wang, M; Wei, J; Zhao, S; Zheng, W; Zhu, X | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Ao, R; Deng, J; Li, D; Li, N; Li, X; Liu, S; Long, Y; Ma, Y; Shi, A; Wan, J; Wen, J; Yu, S; Zhang, Y | 1 |
| DI, LQ; Huang, X; Lu, YY; Luo, ZC; Qi, MY; Shan, JJ; Zhang, W | 1 |
| Chen, B; Di, Z; Guo, Q; Hu, R; Jiang, S; Liu, J; Ma, R; Shi, M; Song, Z; Sun, S; Wu, X; Xu, H | 1 |
| Duan, Y; Lai, J; Li, L; Shao, L; Wang, J; Wang, Y; Xing, X; Yang, Z | 1 |
| Liu, Z; Mu, C; Zhu, W | 1 |
| Arakelian, AG; Chernyshov, SV; Mikoulinskaia, GV; Prokhorov, DA; Sitnikova, DS; Uversky, VN | 1 |
| Anstöter, CS; Dessent, CEH; Uleanya, KO | 1 |
13 review(s) available for glutamic acid and tryptophan
| Article | Year |
|---|---|
Effect of ammonium ions on synaptic transmission in the mammalian central nervous system.
Topics: Ammonia; Animals; Astrocytes; Brain; Calcium; Cell Communication; Central Nervous System; Coma; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Liver; Liver Diseases; Mammals; Membrane Potentials; Neurons; Neurotransmitter Agents; Quaternary Ammonium Compounds; Rabbits; Rats; Receptors, Neurotransmitter; Synaptic Transmission; Tryptophan | 1992 |
[Neural and molecular mechanisms of fatigue and recovery from fatigue].
Topics: Acetylcarnitine; Ascorbic Acid; Biopterins; Brain; Cytokines; Fatigue; Glutamic Acid; Humans; Nerve Net; Serotonin; Tomography, Emission-Computed; Tryptophan | 2003 |
Ammonia toxicity to the brain and creatine.
Topics: Ammonia; Animals; Brain Chemistry; Creatine; Culture Media, Serum-Free; Glutamic Acid; Hyperammonemia; Plasma; Rats; Tryptophan | 2004 |
[Molecular/neural mechanisms of fatigue and the way to overcome fatigue].
Topics: Acetylcarnitine; Animals; Brain; Fatigue; Fatigue Syndrome, Chronic; Glucose; Glutamic Acid; Humans; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Tryptophan | 2007 |
EmrE, a model for studying evolution and mechanism of ion-coupled transporters.
Topics: Antiporters; Escherichia coli Proteins; Evolution, Molecular; Glutamic Acid; Glycine; Membrane Transport Proteins; Protein Multimerization; Protein Structure, Tertiary; Tryptophan | 2009 |
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies.
Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenic Acid; Mitochondrial Diseases; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolinic Acid; Tryptophan | 2009 |
Alterations of amino acid metabolism in osteoarthritis: its implications for nutrition and health.
Topics: Arginine; Creatinine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homoarginine; Humans; Hydroxyproline; Immunologic Factors; Inflammation; Nutritional Requirements; Nutritional Status; Osteoarthritis; Proline; Tryptophan | 2016 |
Kynurenines and Glutamate: Multiple Links and Therapeutic Implications.
Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenine; Tryptophan | 2016 |
Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature.
Topics: Amino Acids; Autism Spectrum Disorder; Body Fluids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Serine; Taurine; Tryptophan | 2017 |
Phytochemical treatments target kynurenine pathway induced oxidative stress.
Topics: Animals; Disease Models, Animal; Glutamic Acid; Humans; Kynurenine; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Phytochemicals; Plant Extracts; Quinolinic Acid; Tryptophan | 2018 |
Metabolomics in patients with psychosis: A systematic review.
Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan | 2018 |
The potential roles of amino acids and their major derivatives in the management of multiple sclerosis.
Topics: Amino Acids; Glutamic Acid; Humans; Multiple Sclerosis; Phenylalanine; Threonine; Tryptophan | 2022 |
Tryptophan metabolism: Mechanism-oriented therapy for neurological and psychiatric disorders.
Topics: Dopamine; Glucocorticoids; Glutamic Acid; Humans; Mental Disorders; Receptors, Aryl Hydrocarbon; Receptors, Nicotinic; Tryptophan; Vitamins | 2022 |
191 other study(ies) available for glutamic acid and tryptophan
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis | 2002 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Topics: Amino Acid Transport Systems; Antiporters; Escherichia coli Proteins; HEK293 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Molecular Docking Simulation; Phenylalanine; Stereoisomerism; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2018 |
Substitution of glutamic acid 109 by aspartic acid alters the substrate specificity and catalytic activity of the beta-subunit in the tryptophan synthase bienzyme complex from Salmonella typhimurium.
Topics: Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Glutamates; Glutamic Acid; Hydroxylamines; Molecular Sequence Data; Mutagenesis, Site-Directed; Salmonella typhimurium; Serine; Spectrophotometry; Substrate Specificity; Tryptophan; Tryptophan Synthase | 1992 |
Tryptophan inhibits the [3H]glutamate uptake into Xenopus oocytes injected with rat brain mRNA.
Topics: Amino Acid Transport System X-AG; Animals; Brain; Brain Chemistry; Glutamates; Glutamic Acid; Glycoproteins; Male; Neurotransmitter Uptake Inhibitors; Oocytes; Rats; Rats, Wistar; RNA, Messenger; Sensitivity and Specificity; Tritium; Tryptophan; Xenopus laevis | 1992 |
Combination of Trp and Glu residues for recognition of mRNA cap structure. Analysis of m7G base recognition site of human cap binding protein (IF-4E) by site-directed mutagenesis.
Topics: Amino Acid Sequence; Binding Sites; Carrier Proteins; Glutamates; Glutamic Acid; Guanosine; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Initiation Factors; RNA Cap-Binding Proteins; RNA Caps; Tryptophan | 1991 |
High resolution 13C-solid state NMR of bacteriorhodopsin: assignment of specific aspartic acids and structural implications of single site mutations.
Topics: Aspartic Acid; Bacteriorhodopsins; Carbon Isotopes; Glutamates; Glutamic Acid; Glycine; Halobacterium; Magnetic Resonance Spectroscopy; Mutation; Tryptophan | 1990 |
Enhanced operator binding by trp superrepressors of Escherichia coli.
Topics: Base Sequence; Binding Sites; Collodion; DNA, Bacterial; Escherichia coli; Filtration; Glutamates; Glutamic Acid; Molecular Sequence Data; Molecular Structure; Mutation; Operon; Protein Conformation; Repressor Proteins; Transcription Factors; Tryptophan | 1990 |
Antimutagenicity and binding of lactic acid bacteria from a Chinese cheese to mutagenic pyrolyzates.
Topics: Amino Acids; Cheese; Food Microbiology; Glutamates; Glutamic Acid; Leuconostoc; Mutagenicity Tests; Mutation; Streptococcus; Tryptophan | 1990 |
Identification of amino acid residues essential for the enzymatic activities of pertussis toxin.
Topics: 2-Hydroxy-5-nitrobenzyl Bromide; Adenosine Diphosphate Ribose; Amino Acid Sequence; Amino Acids; Bacteriophages; Base Sequence; Chemical Phenomena; Chemistry; DNA, Recombinant; Epitopes; Escherichia coli; Gene Expression Regulation; Glutamates; Glutamic Acid; GTP-Binding Proteins; Molecular Sequence Data; Mutation; NAD+ Nucleosidase; Pertussis Toxin; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship; Transfection; Tryptophan; Virulence Factors, Bordetella | 1989 |
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine | 1989 |
Bacteriorhodopsin mutants of Halobacterium sp. GRB. II. Characterization of mutants.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Cysteine; Genes, Bacterial; Glutamates; Glutamic Acid; Glycine; Halobacterium; Molecular Sequence Data; Mutation; Protein Conformation; Tryptophan; Tyrosine | 1989 |
The effects of tritium on embryo development: the embryotoxic effects of [3H]tryptophan.
Topics: Age Factors; Animals; Blastocyst; Cell Compartmentation; Chromosomes; Cleavage Stage, Ovum; Embryo Implantation; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Leucine; Mice; Molecular Weight; Nuclear Proteins; Protein Biosynthesis; RNA, Messenger; Tritium; Tryptophan | 1989 |
Substitution of amino acids in helix F of bacteriorhodopsin: effects on the photochemical cycle.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacteriorhodopsins; Glutamates; Glutamic Acid; Glutamine; Glycine; Hydrogen Bonding; Kinetics; Leucine; Molecular Sequence Data; Mutation; Phenylalanine; Photochemistry; Proline; Protons; Serine; Tryptophan | 1989 |
Darkness stimulates rapid synthesis and release of melatonin in rat retina.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dark Adaptation; Diffusion; Glutamates; Glutamic Acid; Light; Melatonin; Rats; Rats, Inbred Strains; Retina; Serotonin; Tryptophan | 1989 |
Engineering of the active site of human lysozyme: conversion of aspartic acid 53 to glutamic acid and tyrosine 63 to tryptophan or phenylalanine.
Topics: Amino Acid Sequence; Aspartic Acid; Chitin; Genetic Engineering; Glutamates; Glutamic Acid; Humans; Micrococcus; Muramidase; Mutation; Phenylalanine; Structure-Activity Relationship; Substrate Specificity; Tryptophan; Tyrosine | 1987 |
DL-7-azatryptophan and citrulline metabolism in the cyanobacterium Anabaena sp. strain 1F.
Topics: Amino Acids; Bicarbonates; Carbon Radioisotopes; Citrulline; Cyanobacteria; Glutamates; Glutamic Acid; Glutamine; Kinetics; Tryptophan | 1987 |
Effects of amitriptyline on serum glutamate and free tryptophan in rats.
Topics: Amitriptyline; Animals; Glutamates; Glutamic Acid; Male; Muridae; Tryptophan | 1982 |
Abnormal amino acid concentrations in plasma and urine of experimentally diabetic dogs.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Arginine; Diabetes Mellitus, Experimental; Dogs; Female; Glutamates; Glutamic Acid; Histidine; Male; Phenylalanine; Renal Aminoacidurias; Tryptophan; Tyrosine | 1983 |
Tryptophan loading modulates light-induced responses in the mammalian circadian system.
Topics: Animals; Circadian Rhythm; Cricetinae; Glutamic Acid; Immunohistochemistry; Light; Male; Mesocricetus; Microdialysis; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Suprachiasmatic Nucleus; Tryptophan | 1995 |
Identification of Glu173 as the critical amino acid residue for the ADP-ribosyltransferase activity of Clostridium botulinum C3 exoenzyme.
Topics: 3T3 Cells; ADP Ribose Transferases; Animals; Base Sequence; Binding Sites; Botulinum Toxins; Glutamic Acid; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship; Tryptophan | 1995 |
Glutamate, GABA, glycine and taurine modulate serotonin synthesis and release in rostral and caudal rhombencephalic raphe cells in primary cultures.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kinetics; Neurons; Quinoxalines; Quisqualic Acid; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Taurine; Tryptophan | 1993 |
Contributions of tryptophan 24 and glutamate 30 to binding long-lived water molecules in the ternary complex of human dihydrofolate reductase with methotrexate and NADPH studied by site-directed mutagenesis and nuclear magnetic resonance spectroscopy.
Topics: Amino Acid Sequence; Glutamic Acid; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Methotrexate; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Recombinant Proteins; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tryptophan; Water | 1995 |
Crystal structure and site-directed mutagenesis of Bacillus macerans endo-1,3-1,4-beta-glucanase.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Base Sequence; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Glycoside Hydrolases; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Tryptophan | 1995 |
Calcium and membrane binding properties of bovine neurocalcin delta expressed in Escherichia coli.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcium; Calcium-Binding Proteins; Cattle; Cell Membrane; DNA Primers; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Myristic Acid; Myristic Acids; Nerve Tissue Proteins; Neurocalcin; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Protein Processing, Post-Translational; Receptors, Calcium-Sensing; Recombinant Proteins; Spectrometry, Fluorescence; Tryptophan | 1995 |
Site-directed mutagenesis of histidine 93, aspartic acid 180, glutamic acid 205, histidine 290, and aspartic acid 291 at the active site and tryptophan 279 at the raw starch binding site in barley alpha-amylase 1.
Topics: alpha-Amylases; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; Glutamates; Glutamic Acid; Histidine; Hordeum; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Tryptophan | 1993 |
Increased blood-brain barrier permeability of amino acids in chronic hypertension.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cell Membrane Permeability; Cerebellum; Cerebral Cortex; Glutamates; Glutamic Acid; Hypertension; Medulla Oblongata; Organ Specificity; Pons; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Tryptophan | 1993 |
Arthrobacter D-xylose isomerase: chemical modification of carboxy groups and protein engineering of pH optimum.
Topics: Aldose-Ketose Isomerases; Amides; Arthrobacter; Base Sequence; Carbohydrate Epimerases; Glutamates; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Engineering; Thermolysin; Tryptophan | 1993 |
Functional roles of Trp337 and Glu632 in Clostridium glucoamylase, as determined by chemical modification, mutagenesis, and the stopped-flow method.
Topics: Acarbose; Amino Acid Sequence; Base Sequence; Bromosuccinimide; Clostridium; Glucan 1,4-alpha-Glucosidase; Glutamates; Glutamic Acid; Hypoglycemic Agents; Kinetics; Mathematics; Models, Theoretical; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Point Mutation; Protein Conformation; Spectrometry, Fluorescence; Substrate Specificity; Trisaccharides; Tryptophan | 1994 |
Bacterial multidrug resistance is due to a single membrane protein which functions as a drug pump.
Topics: Amino Acid Sequence; Antiporters; Aspartic Acid; Bacterial Proteins; Base Sequence; Carrier Proteins; DNA Mutational Analysis; DNA Primers; Drug Resistance, Microbial; Drug Resistance, Multiple; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Membrane Proteins; Molecular Sequence Data; Phenotype; Proteolipids; Staphylococcus; Tryptophan | 1994 |
Glutamate uptake system in the presynaptic vesicle: glutamic acid analogs as inhibitors and alternate substrates.
Topics: Animals; Cattle; Cerebral Cortex; Cycloleucine; Cysteine; Glutamates; Glutamic Acid; Synaptic Vesicles; Tryptophan | 1993 |
Determination of the pKa values of active-center cysteines, cysteines-32 and -35, in Escherichia coli thioredoxin by Raman spectroscopy.
Topics: Amino Acid Sequence; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Cysteine; Escherichia coli; Glutamates; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Solutions; Spectrum Analysis, Raman; Thioredoxins; Tryptophan; Tyrosine | 1993 |
Predicting the topology of eukaryotic membrane proteins.
Topics: Aspartic Acid; Glutamates; Glutamic Acid; Membrane Proteins; Tryptophan; Tyrosine | 1993 |
Regulation of hypothalamic preprogrowth hormone-releasing factor messenger ribonucleic acid expression in food-deprived rats: a role for histaminergic neurotransmission.
Topics: Animals; Dietary Proteins; Food Deprivation; Gene Expression Regulation; Glutamates; Glutamic Acid; Growth Hormone-Releasing Hormone; Histamine; Histidine; Histidine Decarboxylase; Hypothalamus; Male; Methylhistidines; Neurotransmitter Agents; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tryptophan; Tyrosine | 1993 |
Point mutations characterize KEL10, the KEL3, KEL4, and KEL21 alleles, and the KEL17 and KEL11 alleles.
Topics: Alanine; Alleles; Amino Acid Sequence; Arginine; Base Sequence; Codon; DNA; Exons; Glutamic Acid; Glutamine; Humans; Kell Blood-Group System; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Tryptophan; Valine | 1996 |
The role of Glu87 and Trp89 in the lid of Humicola lanuginosa lipase.
Topics: Acylation; Binding Sites; Chemical Phenomena; Chemistry, Physical; Esters; Fungal Proteins; Glutamic Acid; Hydrolysis; Lipase; Mitosporic Fungi; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Fusion Proteins; Substrate Specificity; Triglycerides; Tryptophan | 1996 |
Mechanistic interpretation of tryptophan fluorescence quenching in the time courses of glutamate dehydrogenase catalyzed reactions.
Topics: Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Glutamic Acid; In Vitro Techniques; Isotopes; Kinetics; Models, Molecular; Molecular Structure; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan | 1996 |
Higher triglycerides, lower high-density lipoprotein cholesterol, and higher systolic blood pressure in lipoprotein lipase-deficient heterozygotes. A preliminary report.
Topics: Adult; Blood Pressure; Body Mass Index; Cholesterol, LDL; Exons; Genetic Carrier Screening; Glutamic Acid; Glycine; Humans; Hyperlipoproteinemia Type I; Isoleucine; Lipoprotein Lipase; Point Mutation; Systole; Threonine; Triglycerides; Tryptophan | 1996 |
Importance of van der Waals contact between Glu 35 and Trp 109 to the catalytic action of human lysozyme.
Topics: Catalysis; Glutamic Acid; Humans; Kinetics; Muramidase; Mutagenesis; Tryptophan; X-Ray Diffraction | 1997 |
Electrostatic influence of QA reduction on the IR vibrational mode of the 10a-ester C==O of HA demonstrated by mutations at residues Glu L104 and Trp L100 in reaction centers from Rhodobacter sphaeroides.
Topics: Amino Acid Sequence; Electrochemistry; Esters; Glutamic Acid; Hydrogen Bonding; Mutation; Pheophytins; Photosynthetic Reaction Center Complex Proteins; Quinones; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared; Tryptophan | 1997 |
The role of Glu73 of barnase in catalysis and the binding of barstar.
Topics: Bacterial Proteins; Binding Sites; Enzyme Stability; Glutamic Acid; Guanosine Monophosphate; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Ribonucleases; RNA; Structure-Activity Relationship; Tryptophan | 1997 |
Factors which stabilize the methylamine dehydrogenase-amicyanin electron transfer protein complex revealed by site-directed mutagenesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Bacterial Proteins; Cloning, Molecular; Copper; Escherichia coli; Glutamic Acid; Indolequinones; Lysine; Metalloproteins; Models, Molecular; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Phenylalanine; Protein Conformation; Quinones; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Tryptophan | 1997 |
Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and noncerebral malaria.
Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Female; Glutamic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Malaria; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Osmolar Concentration; Oxidation-Reduction; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 1998 |
The neurochemical markers in cerebrospinal fluid to differentiate between aseptic and tuberculous meningitis.
Topics: Adult; Amino Acids; Aspartic Acid; Biomarkers; Diagnosis, Differential; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Homocysteine; Humans; Male; Meningitis, Aseptic; Middle Aged; Nitrites; Tryptophan; Tuberculosis, Meningeal; Vitamin B 12 | 1998 |
The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism.
Topics: Acetylcholinesterase; Amino Acid Substitution; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Dealkylation; Enzyme Activation; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Mice; Mutagenesis, Site-Directed; Phosphorylation; Recombinant Proteins; Soman; Stereoisomerism; Time Factors; Tryptophan | 1998 |
Two substrate interaction sites in lignin peroxidase revealed by site-directed mutagenesis.
Topics: Basidiomycota; Enzyme Stability; Glutamic Acid; Glycine; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Peroxidases; Phenylalanine; Protein Folding; Recombinant Proteins; Serine; Spectrophotometry; Substrate Specificity; Tryptophan | 1998 |
Crystal structure of deoxy-human hemoglobin beta6 Glu --> Trp. Implications for the structure and formation of the sickle cell fiber.
Topics: Amino Acid Substitution; Crystallography, X-Ray; Glutamic Acid; Hemoglobin, Sickle; Hemoglobins; Humans; Models, Molecular; Molecular Sequence Data; Protein Conformation; Tryptophan | 1998 |
Mutations in the 1A rod domain segment of the keratin 9 gene in epidermolytic palmoplantar keratoderma.
Topics: Arginine; Base Sequence; Child, Preschool; Conserved Sequence; Cysteine; Epidermolysis Bullosa Simplex; Female; Genes, Dominant; Genes, Recessive; Glutamic Acid; Humans; Keratins; Keratoderma, Palmoplantar; Korea; Male; Microscopy, Electron; Pedigree; Point Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA; Tryptophan | 1998 |
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Asparagine; Carrier Proteins; Cell Membrane; Glutamic Acid; Histidine; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Threonine; Tryptophan | 1999 |
Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities.
Topics: Amino Acids; Animals; Aryldialkylphosphatase; Aspartic Acid; Binding Sites; Bromosuccinimide; Calcium Radioisotopes; Cell Line; Dicyclohexylcarbodiimide; Diethyl Pyrocarbonate; Enzyme Activation; Enzyme Inhibitors; Esterases; Glutamic Acid; Glycosylation; Histidine; Humans; Indicators and Reagents; Kidney; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Rabbits; Recombinant Proteins; Spectrometry, Fluorescence; Terbium; Tryptophan | 1999 |
Seven novel mutations in the adenosine deaminase (ADA) gene in patients with severe and delayed onset combined immunodeficiency: G74C, V129M, G140E, R149W, Q199P, 462delG, and E337del. Mutations in brief no. 142. Online.
Topics: Adenosine Deaminase; Adolescent; Adult; Age of Onset; Arginine; Cysteine; Glutamic Acid; Glutamine; Glycine; Humans; Methionine; Mutation; Proline; Sequence Deletion; Severe Combined Immunodeficiency; Tryptophan; Valine | 1998 |
Structure/activity studies of the anti-MUC1 monoclonal antibody C595 and synthetic MUC1 mucin-core-related peptides and glycopeptides.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Aspartic Acid; Binding, Competitive; Circular Dichroism; Epitopes; Glutamic Acid; Glycopeptides; Glycosylation; Humans; Hydrogen-Ion Concentration; Immunoglobulin G; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mucin-1; Peptide Fragments; Protein Denaturation; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Thermodynamics; Titrimetry; Tryptophan; Tyrosine | 1999 |
Mutagenesis of two conserved tryptophan residues of the E-type ATPases: inactivation and conversion of an ecto-apyrase to an ecto-NTPase.
Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Brain; Chymotrypsin; Conserved Sequence; COS Cells; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Humans; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleoside-Triphosphatase; Protein Folding; Sodium Azide; Transfection; Triazines; Tryptophan | 1999 |
A multinuclear NMR study of the active site of an endoglucanase from a strain of Bacillus. Use of Trp residues as structural probes.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Binding Sites; Cellulase; Clostridium; Deuterium; Glutamic Acid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Alignment; Tryptophan | 1999 |
Conformational heterogeneity of the bacteriopheophytin electron acceptor HA in reaction centers from Rhodopseudomonas viridis revealed by Fourier transform infrared spectroscopy and site-directed mutagenesis.
Topics: Amino Acid Substitution; Benzoquinones; Deuterium Oxide; Electron Transport; Glutamic Acid; Glutamine; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Pheophytins; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Protein Conformation; Protons; Rhodopseudomonas; Spectroscopy, Fourier Transform Infrared; Static Electricity; Tryptophan | 1999 |
Immuno-, phagocytosis-modulating and antitoxic properties of dipeptides are defined by the activity of their constituent amino acids.
Topics: Amino Acids; Animals; Antidotes; Aspartic Acid; Benzene; Dipeptides; Glutamic Acid; Granulocytes; Immune System; Male; Methionine; Mice; Mice, Inbred CBA; Phagocytosis; Rabbits; T-Lymphocytes; Tryptophan | 1999 |
Self-assembled complexes of oligopeptides and metalloporphyrins: measurements of the reorganization and electronic interaction energies for photoinduced electron-transfer reactions.
Topics: Electrons; Glutamic Acid; Metalloporphyrins; Models, Molecular; Molecular Conformation; Oligopeptides; Photochemistry; Protein Conformation; Thermodynamics; Tryptophan; Tyrosine | 2000 |
Remarkable thermal stability of doubly intramolecularly cross-linked hen lysozyme.
Topics: Amino Acid Substitution; Animals; Binding Sites; Calorimetry, Differential Scanning; Chickens; Egg White; Enzyme Stability; Glutamic Acid; Histidine; Hot Temperature; Lysine; Muramidase; Mutagenesis, Site-Directed; Protein Folding; Recombinant Proteins; Thermodynamics; Tryptophan | 2000 |
Two novel mutations in the WASP gene in Wiskott-Aldrich patients of Chile origin: W64R and A124E.
Topics: Alanine; Amino Acid Substitution; Arginine; Chile; Glutamic Acid; Humans; Infant; Male; Point Mutation; Proteins; Tryptophan; Wiskott-Aldrich Syndrome; Wiskott-Aldrich Syndrome Protein | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Biological function and site II Ca2+-induced opening of the regulatory domain of skeletal troponin C are impaired by invariant site I or II Glu mutations.
Topics: Alanine; Animals; Calcium; Chickens; Circular Dichroism; Escherichia coli; Glutamic Acid; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutagenesis, Site-Directed; Myocardium; Plasmids; Protein Binding; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Spectrometry, Fluorescence; Troponin C; Tryptophan; Ultraviolet Rays | 2000 |
Synthesis and characteristics of the human serum albumin-triazine chiral stationary phase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atropine; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fenoprofen; Glutamic Acid; Humans; Ibuprofen; Naproxen; Protein Binding; Serum Albumin; Silicon Dioxide; Spectrophotometry, Ultraviolet; Stereoisomerism; Triazines; Tryptophan; Warfarin | 2000 |
Structural requirements for the specific recognition of an m7G mRNA cap.
Topics: Amino Acid Substitution; Circular Dichroism; Eukaryotic Initiation Factor-4E; Flavins; Glutamic Acid; Guanosine; Hydrogen Bonding; Mutagenesis, Site-Directed; Peptide Initiation Factors; Phenylalanine; RNA Caps; RNA, Messenger; Spectrometry, Fluorescence; Static Electricity; Tryptophan; Tyrosine; Vaccinia virus; Viral Proteins | 2000 |
Differential sensitivity to mutations in a single peptide by two TCRs having identical beta-chains and closely related alpha-chains.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cells, Cultured; Conalbumin; Glutamic Acid; Glycine; Growth Inhibitors; Interleukin-4; Isoleucine; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Peptide Fragments; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes; Tryptophan | 2000 |
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan | 2001 |
Antitumor action of seminal ribonuclease, its dimeric structure, and its resistance to the cytosolic ribonuclease inhibitor.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Antineoplastic Agents; Arginine; Cattle; Cytosol; Dimerization; Disulfides; Drug Resistance; Endoribonucleases; Enzyme Inhibitors; Glutamic Acid; Growth Inhibitors; Lysine; Mice; Mutagenesis, Site-Directed; Proteins; Recombinant Proteins; Semen; Serine; Tryptophan; Tumor Cells, Cultured | 2001 |
Kinetic preference for oriented DNA binding by the yeast TATA-binding protein TBP.
Topics: Coumarins; Dimerization; DNA-Binding Proteins; DNA, Fungal; Energy Transfer; Fungal Proteins; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Peptide Chain Initiation, Translational; Protein Binding; Protein Isoforms; Saccharomyces cerevisiae; Spectrometry, Fluorescence; TATA Box; TATA-Box Binding Protein; Transcription Factors; Tryptophan | 2001 |
The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan.
Topics: Amino Acid Sequence; Anthranilate Synthase; Base Sequence; Binding Sites; Chorismic Acid; Crystallography, X-Ray; Cyclohexenes; DNA, Bacterial; Glutamic Acid; Glutamine; Lyases; Molecular Sequence Data; Nitrogenous Group Transferases; Oligopeptides; ortho-Aminobenzoates; Protein Structure, Secondary; Serratia marcescens; Substrate Specificity; Tryptophan | 2001 |
Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes.
Topics: Alleles; Amino Acid Substitution; Arginine; Blood Glucose; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Genetic Variation; Genotype; Glutamic Acid; Glutamine; Homozygote; Humans; Insulin; Male; Middle Aged; Nuclear Family; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Reference Values; Sweden; Triglycerides; Tryptophan; White People | 2001 |
Snapshots of protein folding. A study on the multiple transition state pathway of cytochrome c(551) from Pseudomonas aeruginosa.
Topics: Acids; Bacterial Proteins; Cytochrome c Group; Fluorescence; Glutamic Acid; Guanidine; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Protein Conformation; Protein Denaturation; Protein Folding; Pseudomonas aeruginosa; Static Electricity; Thermodynamics; Tryptophan; Urea | 2001 |
Prenatal exposure to methyl mercury in rats: focus on changes in kynurenine pathway.
Topics: Animals; Aspartic Acid; Female; Fetus; Glutamic Acid; Hippocampus; Kynurenine; Mercury Poisoning, Nervous System; Methylmercury Compounds; Neurons; ortho-Aminobenzoates; Pregnancy; Prenatal Exposure Delayed Effects; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tryptophan | 2001 |
The covalent structure of the small subunit from Pseudomonas putida amine dehydrogenase reveals the presence of three novel types of internal cross-linkages, all involving cysteine in a thioether bond.
Topics: Amino Acid Sequence; Amino Acids; Cloning, Molecular; Cross-Linking Reagents; Cysteine; Glutamic Acid; Heme; Indolequinones; Mass Spectrometry; Models, Chemical; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Peptides; Protein Binding; Protein Processing, Post-Translational; Pseudomonas putida; Quinones; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Sulfides; Tryptophan; X-Rays | 2001 |
Characterization and biological activities of Chenopodium leaf hemagglutinin (CLH).
Topics: Amino Acids; Animals; Aspartic Acid; Cell Aggregation; Chenopodium; Dose-Response Relationship, Drug; Erythrocytes; Glutamic Acid; Glycine; Hemagglutinins; Lysine; Methionine; Mice; Phenylalanine; Plant Leaves; Rabbits; Rats; Spleen; Thymus Gland; Tryptophan | 2001 |
Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner.
Topics: Alanine; Alcohols; Amino Acid Motifs; Amino Acids; Animals; Blotting, Western; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Leucine; Oocytes; Phosphorylation; Protein Binding; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Time Factors; Tryptophan; Xenopus laevis | 2002 |
Chimaeric gonadotropin-releasing hormone (GnRH) peptides with improved affinity for the catfish (Clarias gariepinus) GnRH receptor.
Topics: Alanine; Animals; Aspartic Acid; Binding Sites; Catfishes; Cell Line; Cell Membrane; Chickens; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Gonadotropin-Releasing Hormone; Humans; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Peptides; Protein Binding; Protein Structure, Tertiary; Receptors, LHRH; Recombinant Fusion Proteins; Transfection; Tryptophan; Tyrosine | 2002 |
A novel gain-of-function mutation of the integrin alpha2 VWFA domain.
Topics: Amino Acid Sequence; Antigens, CD; Cadherins; Collagen; Glutamic Acid; Humans; Integrin alpha2; Integrins; Laminin; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Tertiary; Tryptophan; von Willebrand Factor | 2002 |
Enthalpic homogeneous pair interaction coefficients of L-alpha-amino acids as a hydrophobicity parameter of amino acid side chains.
Topics: Amino Acids; Arginine; Asparagine; Calorimetry; Cysteine; Glutamic Acid; Glutamine; Histidine; Solutions; Stereoisomerism; Thermodynamics; Tryptophan; Water | 2002 |
Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis.
Topics: Amino Acids; Anions; Asparagine; Glutamic Acid; Halogens; Histidine; Hydrolases; Isoleucine; Leucine; Mathematical Computing; Models, Chemical; Mutagenesis, Site-Directed; Phenylalanine; Proline; Quantum Theory; Static Electricity; Tryptophan; Valine | 2002 |
The beta G156C substitution in the F1-ATPase from the thermophilic Bacillus PS3 affects catalytic site cooperativity by destabilizing the closed conformation of the catalytic site.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Bacillus; Binding Sites; Catalysis; Catalytic Domain; Cysteine; Dimethylamines; Enzyme Stability; Glutamic Acid; Glycine; Hydrolysis; Magnesium; Mutagenesis, Site-Directed; Protein Conformation; Proton-Translocating ATPases; Sodium Azide; Tryptophan; Tyrosine; Valine | 2002 |
Mutation of glutamic acid residue 1046 abolishes Jak2 tyrosine kinase activity.
Topics: Angiotensin II; Animals; Blotting, Western; Cell Line; DNA-Binding Proteins; Glutamic Acid; Janus Kinase 2; Ligands; Mutagenesis, Site-Directed; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; STAT1 Transcription Factor; Trans-Activators; Transcription, Genetic; Tryptophan | 2002 |
Expression of an artificial polypeptide with a repeated tripeptide glutamyl-tryptophanyl-lysine in Saccharomyces cerevisiae.
Topics: Amino Acids, Essential; Cloning, Molecular; Culture Media; Electrophoresis, Polyacrylamide Gel; Genes, Synthetic; Glutamic Acid; Lysine; Models, Genetic; Oligopeptides; Plasmids; Recombinant Proteins; Repetitive Sequences, Amino Acid; Saccharomyces cerevisiae; Tryptophan | 2003 |
Engineered fibronectin type III domain with a RGDWXE sequence binds with enhanced affinity and specificity to human alphavbeta3 integrin.
Topics: Alanine; Antibodies, Monoclonal; Biotinylation; Cell Adhesion; DNA Primers; Enzyme-Linked Immunosorbent Assay; Fibronectins; Flow Cytometry; Glutamic Acid; Humans; In Vitro Techniques; Integrin alphaVbeta3; Kinetics; Molecular Conformation; Oligopeptides; Peptide Fragments; Peptide Library; Plasmids; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Tryptophan; Tumor Cells, Cultured | 2003 |
Copper(II) diamino acid complexes: quantum chemical computations regarding diastereomeric effects on the energy of complexation.
Topics: Amino Acids, Diamino; Cholesterol; Copper; Glutamic Acid; Hydrogen Bonding; Models, Molecular; Phenylalanine; Quantum Theory; Stereoisomerism; Thermodynamics; Tryptophan | 2003 |
Trp17 and Glu20 residues in conserved WMN(D/E)PN motif are essential for Aspergillus ficuum endoinulinase (EC 3.2.1.7) activity.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Aspergillus; Conserved Sequence; DNA Primers; Glutamic Acid; Glycoside Hydrolases; Mutagenesis, Site-Directed; Recombinant Proteins; Saccharomyces cerevisiae; Tryptophan | 2003 |
EFFECT OF CATIONS UPON HYDROPHOBICITY OF YEASTS GROWN IN AMINO ACID MEDIA.
Topics: Amino Acids; Ammonium Compounds; Cations; Chlorides; Culture Media; Glutamic Acid; Histidine; Hydrophobic and Hydrophilic Interactions; Lysine; Nitrogen; Phenylalanine; Proline; Quaternary Ammonium Compounds; Research; Tryptophan; Tyrosine; Valine; Yeasts | 1963 |
N-terminal extension of canine glutamine synthetase created by splicing alters its enzymatic property.
Topics: Adenosine Triphosphate; Alternative Splicing; Animals; Blotting, Western; Chlorides; Chromatography, Gel; DNA Primers; Dogs; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Exons; Glutamate-Ammonia Ligase; Glutamic Acid; Green Fluorescent Proteins; Humans; Hydroxylamine; Ions; Kinetics; Luminescent Proteins; Metals; Methionine Sulfoximine; Mice; Protein Biosynthesis; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; RNA, Messenger; Spectrometry, Fluorescence; Tissue Distribution; Transcription, Genetic; Tryptophan | 2004 |
Structural characterization of the peroxodiiron(III) intermediate generated during oxygen activation by the W48A/D84E variant of ribonucleotide reductase protein R2 from Escherichia coli.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Escherichia coli Proteins; Ferric Compounds; Ferrous Compounds; Glutamic Acid; Oxygen; Oxygenases; Protein Subunits; Ribonucleotide Reductases; Spectroscopy, Mossbauer; Spectrum Analysis; Tryptophan; X-Rays | 2003 |
Usefulness of amino acid composition to discriminate between honeydew and floral honeys. Application to honeys from a small geographic area.
Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Cucumis; Flowers; Glutamic Acid; Honey; Spain; Tryptophan | 2004 |
Understanding protein-ligand interactions: the price of protein flexibility.
Topics: Animals; Benzamidines; Binding Sites; Catalytic Domain; Cattle; Crystallography, X-Ray; Factor Xa; Glutamic Acid; Kinetics; Ligands; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Protein Conformation; Protein Folding; Structure-Activity Relationship; Trypsin; Trypsin Inhibitors; Tryptophan | 2004 |
Nitrogen metabolism in the African lungfish (Protopterus dolloi) aestivating in a mucus cocoon on land.
Topics: Africa; Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Estivation; Fishes; Glutamic Acid; Time Factors; Tryptophan | 2004 |
Studies on Corynebacterium diphtheriae. V. The attitude of diphtheria bacillus to some growth factors (calcium pantothenate, glutamic acid and tryptophane).
Topics: Bacillus; Corynebacterium diphtheriae; Diphtheria; Glutamic Acid; Intercellular Signaling Peptides and Proteins; Pantothenic Acid; Tryptophan | 1951 |
Mutational analysis of different regions in the coxsackievirus 2B protein: requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication.
Topics: Amino Acid Sequence; Animals; Arginine; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Chlorocebus aethiops; COS Cells; Dimerization; DNA Mutational Analysis; Enterovirus; Glutamic Acid; Hygromycin B; Kinetics; Lysine; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Oligonucleotides, Antisense; Permeability; Protein Structure, Tertiary; RNA; Subcellular Fractions; Time Factors; Transfection; Tryptophan; Two-Hybrid System Techniques; Viral Nonstructural Proteins; Virus Replication | 2004 |
Amino acids and asthma: a case-control study.
Topics: Adolescent; Adult; Aged; Amino Acids; Arginine; Asthma; Case-Control Studies; Cystine; Fasting; Female; Glutamic Acid; Glutamine; Glutathione; Glycine; Humans; Male; Methionine; Middle Aged; Odds Ratio; Phenylalanine; Tryptophan | 2004 |
Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.
Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Enzyme Inhibitors; Glutamic Acid; Homocysteine; Humans; Kinetics; Ligands; Methionine; Methyltransferases; Mutagenesis, Site-Directed; Protein Binding; Sarcosine; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan; Tyrosine | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Central core disease mutations R4892W, I4897T and G4898E in the ryanodine receptor isoform 1 reduce the Ca2+ sensitivity and amplitude of Ca2+-dependent Ca2+ release.
Topics: Adenosine Triphosphate; Arginine; Calcium; Calcium Isotopes; Calcium-Transporting ATPases; Cell Line; Glutamic Acid; Glycine; Humans; Isoleucine; Kidney; Microsomes; Mutagenesis, Site-Directed; Mutation, Missense; Myopathy, Central Core; Oxalates; Photometry; Protein Isoforms; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Threonine; Tryptophan | 2004 |
Single-point mutations at the surface of MB-1Trp lead to important changes in its conformational properties.
Topics: Amino Acid Substitution; Animal Feed; Animals; Cattle; Circular Dichroism; Dietary Proteins; Glutamic Acid; Leucine; Point Mutation; Protein Denaturation; Protein Engineering; Protein Structure, Tertiary; Tryptophan | 2004 |
Directed evolution of a glycosynthase from Agrobacterium sp. increases its catalytic activity dramatically and expands its substrate repertoire.
Topics: beta-Glucosidase; Binding Sites; Biochemical Phenomena; Biochemistry; Directed Molecular Evolution; Dose-Response Relationship, Drug; Doxorubicin; Gene Library; Genetic Vectors; Glutamic Acid; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis; Mutation; Protein Binding; Protein Transport; Rhizobium; Sequence Analysis, DNA; Substrate Specificity; Tryptophan | 2004 |
X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior.
Topics: Crystallography, X-Ray; Fluorescence; Glutamic Acid; Guanidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Micrococcal Nuclease; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Denaturation; Thermodynamics; Tryptophan | 2004 |
Sugar recognition by the lactose permease of Escherichia coli.
Topics: Binding Sites; Biological Transport; Bromosuccinimide; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Hydrogen Bonding; Kinetics; Mass Spectrometry; Membrane Transport Proteins; Models, Biological; Models, Molecular; Mutation; Oxygen; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry; Substrate Specificity; Time Factors; Tryptophan | 2004 |
Different functional roles of arginine residues 39 and 61 and tyrosine residue 98 in transport and channel mode of the glutamate transporter EAAC1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Anions; Arginine; Biological Transport; Chlorine; Electrophysiology; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Mice; Mutation; Nitrates; Oocytes; Patch-Clamp Techniques; Protein Binding; Symporters; Tryptophan; Xenopus | 2004 |
Developing promiscuous glycosidases for glycoside synthesis: residues W433 and E432 in Sulfolobus solfataricus beta-glycosidase are important glucoside- and galactoside-specificity determinants.
Topics: Alkylation; Amino Acid Sequence; Galactose; Glucose; Glucosidases; Glutamic Acid; Glycosylation; Kinetics; Methylation; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Sequence Alignment; Substrate Specificity; Sulfolobus solfataricus; Tryptophan | 2005 |
Release of oxidized plastocyanin from photosystem I limits electron transfer between photosystem I and cytochrome b6f complex in vivo.
Topics: Animals; Binding Sites; Chlamydomonas; Cytochrome b6f Complex; Dose-Response Relationship, Drug; Electrons; Glutamic Acid; Glutamine; Kinetics; Mutation; NADP; Oxygen; Phenotype; Photosynthesis; Photosystem I Protein Complex; Plastocyanin; Protein Binding; Serine; Spectrophotometry; Time Factors; Tryptophan | 2005 |
Short communication: Amino acids antagonistic to the amino acids inhibitory for growth rate of mixed ruminal bacteria.
Topics: Amino Acids; Animals; Bacteria; Cattle; Diet; Feedback, Physiological; Female; Fermentation; Glutamic Acid; Isoleucine; Leucine; Nitrogen; Phenylalanine; Rumen; Threonine; Tryptophan; Tyrosine; Valine | 2005 |
Bipolar mania and plasma amino acids: increased levels of glycine.
Topics: Adult; Aged; Bipolar Disorder; Case-Control Studies; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Tryptophan | 2006 |
Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Catalysis; Centrifugation, Density Gradient; Dose-Response Relationship, Drug; Giardia lamblia; Glutamic Acid; Glycerol; Green Fluorescent Proteins; Guanine; Guanosine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Methylation; Methyltransferases; Molecular Sequence Data; Recombinant Proteins; RNA; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Transfection; tRNA Methyltransferases; Tryptophan | 2005 |
Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?
Topics: Adenosine Diphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Databases, Protein; Evolution, Molecular; Glutamic Acid; Histidine; Humans; Models, Genetic; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Monte Carlo Method; Protein Conformation; Protein Kinases; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tryptophan; Tyrosine; Water | 2005 |
A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.
Topics: Alanine; Animals; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrophysiology; Glutamic Acid; Ions; Kainic Acid; Kinetics; Ligands; Models, Biological; Models, Chemical; Models, Molecular; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, AMPA; RNA, Complementary; Tryptophan; Tyrosine; Xenopus laevis | 2005 |
Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly.
Topics: Amino Acid Sequence; Animals; Cell Line; Glutamic Acid; Glutamine; Glycine; Hedgehog Proteins; Holoprosencephaly; Humans; Mice; Mice, Inbred C3H; Molecular Sequence Data; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Signal Transduction; Temperature; Trans-Activators; Tryptophan | 2005 |
Changes in plasma amino acids after electroconvulsive therapy of depressed patients.
Topics: Adult; Aged; Aspartic Acid; Depressive Disorder, Major; Electroconvulsive Therapy; Electroencephalography; Electromyography; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Time Factors; Tryptophan | 2005 |
Augmenting neurotransmitter release by enhancing the apparent Ca2+ affinity of synaptotagmin 1.
Topics: Animals; Calcium; Cations, Divalent; Cells, Cultured; Glutamic Acid; Mice; Mice, Knockout; Models, Molecular; Mutation; Protein Structure, Tertiary; Synaptotagmin I; Time Factors; Tryptophan | 2005 |
Conformational changes in sarcoplasmic reticulum Ca(2+)-ATPase mutants: effect of mutations either at Ca(2+)-binding site II or at tryptophan 552 in the cytosolic domain.
Topics: Adenosine Triphosphate; Binding Sites; Calcium; Calcium-Transporting ATPases; Cations, Divalent; Chromatography, Affinity; Cytoplasm; Gene Expression; Glutamic Acid; Magnesium; Mutation; Nitrilotriacetic Acid; Organometallic Compounds; Phosphorus; Phosphorylation; Protein Conformation; Saccharomyces cerevisiae; Sarcoplasmic Reticulum; Tryptophan | 2006 |
Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Glutamic Acid; Glycine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Peptides, Cyclic; Proline; Rhodococcus; Tryptophan | 2006 |
Observing an induced-fit mechanism during sequence-specific DNA methylation.
Topics: Binding Sites; DNA; DNA Methylation; Glutamic Acid; Kinetics; Lysine; Microscopy, Fluorescence; Models, Genetic; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutation; Nucleic Acid Conformation; Thermodynamics; Tryptophan | 2006 |
Effects of tryptophan photoproducts in the circadian timing system: searching for a physiological role for aryl hydrocarbon receptor.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carbazoles; Cell Cycle Proteins; Cell Line; Circadian Rhythm; Cryptochromes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Enzyme Induction; Flavoproteins; Glutamic Acid; In Vitro Techniques; Indoles; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Period Circadian Proteins; Photolysis; Proto-Oncogene Proteins c-fos; Rats; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction; Sunlight; Suprachiasmatic Nucleus; Time Factors; Tryptophan | 2007 |
Modulation of the W748S mutation in DNA polymerase gamma by the E1143G polymorphismin mitochondrial disorders.
Topics: Amino Acid Sequence; Amino Acid Substitution; Catalytic Domain; DNA; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Enzyme Stability; Glutamic Acid; Glycine; Humans; Mitochondrial Diseases; Models, Molecular; Molecular Sequence Data; Mutation; Nucleotides; Polymorphism, Genetic; Protein Conformation; Serine; Tryptophan | 2006 |
Copper and zinc promote interactions between membrane-anchored peptides of the metal binding domain of the prion protein.
Topics: Amino Acid Sequence; Binding Sites; Computer Simulation; Copper; Crystallography, X-Ray; Dimyristoylphosphatidylcholine; Glutamic Acid; Liposomes; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptide Fragments; Prions; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Pyrenes; Solvents; Spectrometry, Fluorescence; Static Electricity; Tryptophan; Water; Zinc | 2007 |
The genetic polymorphisms of beta3-adrenergic receptor (AR) Trp64Arg and beta2-AR Gln27Glu are associated with obesity in Chinese male hypertensive patients.
Topics: Aged; Arginine; Base Sequence; DNA Primers; Glutamic Acid; Glycine; Humans; Hypertension; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Adrenergic, beta-3; Tryptophan | 2007 |
Conformational changes in a bacterial multidrug transporter are phosphatidylethanolamine-dependent.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Phosphatidylethanolamines; Protein Conformation; Spectroscopy, Fourier Transform Infrared; Substrate Specificity; Tryptophan | 2007 |
The contribution of tryptophan residues to conformational changes in clostridial glutamate dehydrogenase--W64 and W449 as mediators of the cooperative response to glutamate.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Circular Dichroism; Clostridium symbiosum; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Mutation; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Temperature; Tryptophan | 2007 |
PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.
Topics: Adenine; Amino Acid Motifs; Amino Acid Sequence; Arginine; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Glutamic Acid; Holoenzymes; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Tryptophan; Tyrosine | 2007 |
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan | 2007 |
EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activity.
Topics: Amino Acid Sequence; Bacterial Proteins; Blotting, Western; Cysteine Endopeptidases; Glutamic Acid; Glycoside Hydrolases; Hydrolysis; Immunoglobulin G; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Polysaccharides; Protein Structure, Secondary; Sequence Homology, Amino Acid; Streptococcus pyogenes; Structural Homology, Protein; Structure-Activity Relationship; Tryptophan | 2008 |
New insights into the mechanism of enzymatic chlorination of tryptophan.
Topics: Amino Acid Substitution; Bacterial Proteins; Catalysis; Catalytic Domain; Chlorine; Glutamic Acid; Halogenation; Lysine; Mutation; Oxidoreductases; Protein Structure, Secondary; Pseudomonas fluorescens; Tryptophan | 2008 |
Cerebrolysin lowers kynurenic acid formation--an in vitro study.
Topics: Adult; Amino Acids; Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Glutamic Acid; Humans; In Vitro Techniques; Kynurenic Acid; Liver; Male; Neuroprotective Agents; Postmortem Changes; Rats; Rats, Sprague-Dawley; Time Factors; Transaminases; Tryptophan | 2009 |
Glutamic acid residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity.
Topics: Amino Acid Substitution; Amino Acids; Anilino Naphthalenesulfonates; Animals; Chromatography, Gel; Circular Dichroism; Dithiothreitol; Glutamic Acid; Heat-Shock Proteins; Hot Temperature; Humans; Hydrophobic and Hydrophilic Interactions; Insulin; Mice; Molecular Chaperones; Molecular Weight; Neoplasm Proteins; Oxidation-Reduction; Protein Denaturation; Protein Stability; Protein Structure, Secondary; Recombinant Proteins; Sequence Analysis, Protein; Spectrometry, Fluorescence; Tryptophan | 2008 |
The role of amino acids in the long-distance transport of La and Y in the xylem sap of tomato.
Topics: Amino Acids; Aspartic Acid; Biological Transport; Chromatography, High Pressure Liquid; Glutamic Acid; Histidine; Lanthanum; Solanum lycopersicum; Tryptophan; Xylem; Yttrium | 2009 |
Presentation of cytosolically stable peptides by HLA-B27 is not dependent on the canonic interactions of N-terminal basic residues in the A pocket.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antigen Presentation; Cell Line, Tumor; Cytosol; Gene Expression Regulation; Glutamic Acid; HLA-B Antigens; HLA-B27 Antigen; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ligands; Peptide Fragments; Protein Binding; Serine; Signal Transduction; Thermodynamics; Threonine; Tryptophan | 2009 |
Enhancement of aluminum intake of mice by specific amino acids: long-term dosing.
Topics: Aluminum; Animals; Bone and Bones; Brain; Calcium; Drug Synergism; Female; Glutamic Acid; Glycine; Heart; Kidney; Liver; Lung; Magnesium; Mice; Myocardium; Tissue Distribution; Tryptophan | 2007 |
Tryptophan as a three-way switch in regulating the function of the secretory signalling glycoprotein (SPS-40) from mammary glands: structure of SPS-40 complexed with 2-methylpentane-2,4-diol at 1.6 A resolution.
Topics: Animals; Carbohydrates; Cattle; Crystallography, X-Ray; Female; Glutamic Acid; Glycols; Glycoproteins; Hydrogen Bonding; Isoleucine; Mammary Glands, Animal; Models, Molecular; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tryptophan | 2009 |
Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan.
Topics: Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorylation; Phosphoserine; Protein Folding; Protein Processing, Post-Translational; Serine; Threonine; Tryptophan; Tyrosine | 2009 |
A single glutamate residue controls the oligomerization, function, and stability of the aquaglyceroporin GlpF.
Topics: Aquaglyceroporins; Bacterial Proteins; Cell Membrane; Cloning, Molecular; Crystallography, X-Ray; Drug Stability; Escherichia coli; Gene Amplification; Glutamic Acid; Membrane Proteins; Models, Molecular; Oligopeptides; Plasmids; Polymerase Chain Reaction; Protein Conformation; Tryptophan | 2010 |
In situ ATR-FTIR investigation on the preparation and enantiospecificity of chiral polyelectrolyte multilayers.
Topics: Ascorbic Acid; Electrolytes; Glutamic Acid; Hydrogen-Ion Concentration; Osmolar Concentration; Permeability; Polyelectrolytes; Polylysine; Polymers; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Sulfonic Acids; Tryptophan | 2009 |
Mutational analysis of calnexin.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Calcium; Calnexin; Circular Dichroism; Dose-Response Relationship, Drug; Glutamic Acid; Immunoglobulins; Kinetics; Mice; Mutagenesis, Site-Directed; Mutant Proteins; Mutation; Protein Binding; Protein Conformation; Protein Denaturation; Protein Disulfide-Isomerases; Surface Plasmon Resonance; Temperature; Tryptophan; Zinc | 2011 |
Requirements for catalysis in the Cre recombinase active site.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Biocatalysis; Catalytic Domain; Glutamic Acid; Histidine; Integrases; Lysine; Models, Molecular; Molecular Sequence Data; Recombination, Genetic; Tryptophan; Tyrosine; Vanadates | 2010 |
Mutational analysis of the carbohydrate binding activity of the tobacco lectin.
Topics: Amino Acid Sequence; Carbohydrate Metabolism; Carbohydrate Sequence; Conserved Sequence; DNA Mutational Analysis; Glutamic Acid; Lectins; Models, Molecular; Molecular Sequence Data; Nicotiana; Pichia; Recombinant Proteins; Sequence Alignment; Tryptophan | 2010 |
Acquisition of Raman spectra of amino acids using portable instruments: outdoor measurements and comparison.
Topics: Alanine; Amino Acids; Asparagine; Aspartic Acid; beta-Alanine; Glutamic Acid; Glutamine; Glycine; Methionine; Proline; Research Design; Robotics; Serine; Spectrum Analysis, Raman; Transportation; Tryptophan; Tyrosine; Workplace | 2010 |
Crystal structures of CO and NO adducts of MauG in complex with pre-methylamine dehydrogenase: implications for the mechanism of dioxygen activation.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Carbon Monoxide; Crystallography, X-Ray; Cytochrome-c Peroxidase; Ferrous Compounds; Glutamic Acid; Heme; Hemeproteins; Indolequinones; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nitric Oxide; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Paracoccus denitrificans; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry; Substrate Specificity; Tryptophan | 2011 |
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?
Topics: Adult; Aged; Depressive Disorder, Major; Female; Glutamic Acid; Gyrus Cinguli; Humans; Male; Microglia; Middle Aged; Quinolinic Acid; Serotonin; Synaptic Transmission; Tryptophan | 2011 |
Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population.
Topics: Adult; Areca; Arginine; Arylamine N-Acetyltransferase; Case-Control Studies; Codon; DNA Repair; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Glycine; Heterozygote; Homozygote; Humans; India; Lysine; Male; Methionine; Multifactor Dimensionality Reduction; Oral Submucous Fibrosis; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Tobacco, Smokeless; Tryptophan; X-ray Repair Cross Complementing Protein 1 | 2012 |
The role of the second and third extracellular loops of the adenosine A1 receptor in activation and allosteric modulation.
Topics: Alanine; Allosteric Regulation; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Glutamic Acid; Humans; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptor, Adenosine A1; Saccharomyces cerevisiae; Sequence Alignment; Thiophenes; Tryptophan | 2012 |
In vitro degradation of lysine by ruminal fluid-based fermentations and by Fusobacterium necrophorum.
Topics: Acetic Acid; Alanine; Animals; Cattle; Fermentation; Fusobacterium necrophorum; Gastric Juice; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Lysine; Methionine; Propionates; Rumen; Tryptophan | 2013 |
Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity.
Topics: Acquired Immunodeficiency Syndrome; Brain; Cell Line; Cell Survival; Dopamine; Fabaceae; Glutamic Acid; HIV; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Leukocytes, Mononuclear; Melatonin; Molecular Structure; Plant Extracts; Psychotropic Drugs; Seeds; Serotonin; Tryptophan; Virus Replication | 2013 |
Functional identification of the general acid and base in the dehydration step of indole-3-glycerol phosphate synthase catalysis.
Topics: Anti-Bacterial Agents; Catalysis; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Indole-3-Glycerol-Phosphate Synthase; Lysine; Mutagenesis, Site-Directed; Protein Engineering; Solvents; Tryptophan; Viscosity | 2013 |
Carboxyl group of Glu113 is required for stabilization of the diferrous and bis-Fe(IV) states of MauG.
Topics: Crystallography, X-Ray; Ferric Compounds; Ferrous Compounds; Glutamic Acid; Heme; Hemeproteins; Hydrogen Peroxide; Indolequinones; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Protein Processing, Post-Translational; Tryptophan | 2013 |
Structural and mutational analysis of substrate recognition in kojibiose phosphorylase.
Topics: Amino Acid Substitution; Bacterial Proteins; Catalytic Domain; Disaccharides; Glucose; Glucosyltransferases; Glutamic Acid; Glycoside Hydrolases; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Phosphates; Protein Conformation; Recombinant Proteins; Substrate Specificity; Sulfates; Thermoanaerobacter; Threonine; Tryptophan; X-Ray Diffraction | 2014 |
Dual salt mixtures in mixed mode chromatography with an immobilized tryptophan ligand influence the removal of aggregated monoclonal antibodies.
Topics: Antibodies, Monoclonal; Chromatography, Gel; Chromatography, Ion Exchange; Citrates; Glutamic Acid; Immobilized Proteins; Ligands; Sodium Acetate; Sodium Chloride; Sodium Citrate; Tryptophan | 2014 |
NMDA antagonists as Parkinson's disease therapy: disseminating the evidence.
Topics: Animals; Antiparkinson Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Parkinson Disease; Receptors, N-Methyl-D-Aspartate; Tryptophan | 2014 |
The C-glycosyltransferase IroB from pathogenic Escherichia coli: identification of residues required for efficient catalysis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Biocatalysis; Catalytic Domain; Enterobactin; Escherichia coli Proteins; Glucosyltransferases; Glutamic Acid; Glycosylation; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Siderophores; Structural Homology, Protein; Tryptophan; Uridine Diphosphate Glucose; Uropathogenic Escherichia coli | 2014 |
A tripeptide isolated from Bothrops atrox venom has neuroprotective and neurotrophic effects on a cellular model of Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Bothrops; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dopamine; Dopaminergic Neurons; Glutamic Acid; Mitochondria; Models, Biological; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Peptides; Rats; Tryptophan; Valine; Venoms | 2015 |
Investigation of the GPR39 zinc receptor following inhibition of monoaminergic neurotransmission and potentialization of glutamatergic neurotransmission.
Topics: alpha-Methyltyrosine; Animals; Dopamine; Fenclonine; Frontal Lobe; Glutamic Acid; Hippocampus; Male; Mice; Mice, Knockout; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Receptors, G-Protein-Coupled; Serotonin; Synaptic Transmission; Tryptophan; Tyrosine; Zinc | 2015 |
Preorganized Peptide Scaffolds as Mimics of Phosphorylated Proteins Binding Sites with a High Affinity for Uranyl.
Topics: Amino Acid Sequence; Binding Sites; Calcium; Chelating Agents; Circular Dichroism; Glutamic Acid; Imino Acids; Molecular Mimicry; Osteopontin; Peptides, Cyclic; Phosphopeptides; Phosphoserine; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Tryptophan; Uranyl Nitrate | 2015 |
Multiprobe molecular imaging of an NMDA receptor hypofunction rat model for glutamatergic dysfunction.
Topics: Animals; Brain; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenine; Male; Molecular Imaging; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tryptophan | 2016 |
Tryptophan Metabolism and White Matter Integrity in Schizophrenia.
Topics: Adult; Analysis of Variance; Anisotropy; Diffusion Tensor Imaging; Female; Glutamic Acid; Humans; Kynurenine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan; White Matter; Young Adult | 2016 |
Novel pH-Sensitive Cyclic Peptides.
Topics: Amanitins; Animals; Female; Glutamic Acid; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Mammary Neoplasms, Animal; Mice; Molecular Structure; Peptides, Cyclic; Tryptophan | 2016 |
Investigation of the protective effect of Paeonia lactiflora on Semen Strychni-induced neurotoxicity based on monitoring nine potential neurotoxicity biomarkers in rat serum and brain tissue.
Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Dopamine; Drugs, Chinese Herbal; Glutamic Acid; Male; Nerve Growth Factor; Neuroprotective Agents; Paeonia; Plant Extracts; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 2017 |
Rational design and metabolic analysis of Escherichia coli for effective production of L-tryptophan at high concentration.
Topics: Antidepressive Agents, Second-Generation; Biosynthetic Pathways; Culture Media; Cytosol; Escherichia coli; Fermentation; Glutamic Acid; Metabolic Engineering; Tryptophan | 2017 |
Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants.
Topics: Adult; Arginine; Citrulline; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Indoleacetic Acids; Infusions, Intravenous; Ketamine; Male; Metabolomics; Methionine; Middle Aged; Ornithine; Phenotype; Phospholipids; Tryptophan; Urea | 2016 |
Two adjacent phenylalanines in the NMDA receptor GluN2A subunit M3 domain interactively regulate alcohol sensitivity and ion channel gating.
Topics: Ethanol; Glutamic Acid; HEK293 Cells; Humans; Ion Channel Gating; Mutation; Phenylalanine; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Tryptophan | 2017 |
Metabolic profiling of tyrosine, tryptophan, and glutamate in human urine using gas chromatography-tandem mass spectrometry combined with single SPE cleanup.
Topics: Biomarkers; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Humans; Limit of Detection; Metabolome; Metabolomics; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2017 |
Assessment of the Neuroprotective Effects of Arginine-Rich Protamine Peptides, Poly-Arginine Peptides (R12-Cyclic, R22) and Arginine-Tryptophan-Containing Peptides Following In Vitro Excitotoxicity and/or Permanent Middle Cerebral Artery Occlusion in Rats
Topics: Amino Acids; Animals; Arginine; Astrocytes; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Drug Evaluation, Preclinical; Glutamic Acid; In Vitro Techniques; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Oligopeptides; Peptides, Cyclic; Protamines; Rats; Rats, Sprague-Dawley; Tryptophan | 2017 |
Contrasting effects of vortioxetine and paroxetine on pineal gland biochemistry in a tryptophan-depletion model of depression in female rats.
Topics: Administration, Oral; Animals; Antidepressive Agents, Second-Generation; Depressive Disorder; Disease Models, Animal; Female; Glutamic Acid; Melatonin; Norepinephrine; Paroxetine; Pineal Gland; Piperazines; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA-Binding Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Tryptophan; Vortioxetine | 2017 |
Chronic Mild Stress Alters Kynurenine Pathways Changing the Glutamate Neurotransmission in Frontal Cortex of Rats.
Topics: Animals; Antidepressive Agents; Chronic Disease; Cytokines; Frontal Lobe; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenic Acid; Kynurenine; Male; Metabolic Networks and Pathways; Quinolinic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Stress, Psychological; Synaptic Transmission; Tryptophan | 2019 |
The Transmembrane Domain of Synaptobrevin Influences Neurotransmitter Flux through Synaptic Fusion Pores.
Topics: Amino Acid Substitution; Animals; Biological Transport; Calcium; Computer Simulation; Diffusion; Exocytosis; Female; Gene Knockout Techniques; Glutamic Acid; Hippocampus; Kinetics; Male; Membrane Fusion; Mice; Miniature Postsynaptic Potentials; Models, Biological; Neurons; Patch-Clamp Techniques; Protein Domains; SNARE Proteins; Tryptophan; Vesicle-Associated Membrane Protein 2 | 2018 |
Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep.
Topics: Animals; Glutamic Acid; Homovanillic Acid; Humans; Lactic Acid; Metabolomics; Mice; Motor Cortex; Prefrontal Cortex; Pyruvic Acid; Sleep; Sleep Deprivation; Tryptophan; Uridine; Wakefulness | 2018 |
Central metabolic pathway modification to improve L-tryptophan production in Escherichia coli.
Topics: Acetic Acid; Batch Cell Culture Techniques; Bioreactors; Citric Acid; Citric Acid Cycle; Escherichia coli; Escherichia coli Proteins; Fermentation; Gene Expression Regulation, Bacterial; Glutamic Acid; Humans; Industrial Microbiology; Kinetics; Metabolic Engineering; Phosphoenolpyruvate; Plasmids; Transformation, Bacterial; Tryptophan | 2019 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
Development of an underivatized LC-MS/MS method for quantitation of 14 neurotransmitters in rat hippocampus, plasma and urine: Application to CUMS induced depression rats.
Topics: Animals; Blood Chemical Analysis; Chromatography, Liquid; Depression; Disease Models, Animal; Glutamic Acid; Hippocampus; Kynurenic Acid; Kynurenine; Limit of Detection; Linear Models; Male; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Tryptophan; Urinalysis | 2019 |
Untargeted metabolomics analysis of rat hippocampus subjected to sleep fragmentation.
Topics: Animals; Biomarkers; Chromatography, Liquid; Glutamic Acid; Hippocampus; Male; Mass Spectrometry; Metabolome; Metabolomics; Physical Conditioning, Animal; Rats; Rats, Wistar; Sleep; Sleep Deprivation; Tryptophan | 2019 |
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Topics: Alleles; Animals; Bone Morphogenetic Proteins; CRISPR-Cas Systems; Female; Gene Deletion; Gene Editing; Genes, Reporter; Genetic Engineering; Genome; Glutamic Acid; Green Fluorescent Proteins; Growth Differentiation Factors; Hematopoietic Stem Cells; Homozygote; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Myeloid Cells; Phenotype; Protein Domains; Tryptophan | 2019 |
Structure and dynamics at N- and C-terminal regions of intrinsically disordered human c-Myc PEST degron reveal a pH-induced transition.
Topics: Amino Acid Sequence; Aspartic Acid; Cloning, Molecular; Cysteine; Escherichia coli; Gene Expression; Genetic Vectors; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Indoles; Intrinsically Disordered Proteins; Molecular Dynamics Simulation; Neoplasm Proteins; Phosphatidylcholines; Protein Folding; Protein Structure, Secondary; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Spectrometry, Fluorescence; Staining and Labeling; Tryptophan | 2020 |
Neurotransmitter and tryptophan metabolite concentration changes in the complete Freund's adjuvant model of orofacial pain.
Topics: Animals; Facial Pain; Freund's Adjuvant; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Trigeminal Caudal Nucleus; Tryptophan; Vibrissae | 2020 |
The growth of Arabidopsis primary root is repressed by several and diverse amino acids through auxin-dependent and independent mechanisms and MPK6 kinase activity.
Topics: Amino Acids; Arabidopsis; Arabidopsis Proteins; Glutamic Acid; Indoleacetic Acids; Leucine; Lysine; Mitogen-Activated Protein Kinases; Plant Growth Regulators; Plant Root Cap; Plant Roots; Seedlings; Tryptophan | 2021 |
Plasma amino acids profile in first-episode psychosis, unaffected siblings and community-based controls.
Topics: Adult; Amino Acids; Antipsychotic Agents; Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Glycine; Humans; Linear Models; Male; Proline; Psychotic Disorders; Siblings; Tryptophan; Young Adult | 2020 |
Determination and Application of Nineteen Monoamines in the Gut Microbiota Targeting Phenylalanine, Tryptophan, and Glutamic Acid Metabolic Pathways.
Topics: Animals; Biogenic Monoamines; Gastrointestinal Microbiome; Glutamic Acid; Male; Metabolic Networks and Pathways; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Sprague-Dawley; Tryptophan | 2021 |
Prospective study on the association between serum amino acid profiles and depressive symptoms among the Japanese working population.
Topics: Adult; Aged; Arginine; Chromatography, Liquid; Depression; Employment; Female; Glutamic Acid; Health Surveys; Humans; Japan; Logistic Models; Male; Mass Spectrometry; Middle Aged; Odds Ratio; Prospective Studies; Tryptophan | 2021 |
Towards risk stratification and prediction of disease severity and mortality in COVID-19: Next generation metabolomics for the measurement of host response to COVID-19 infection.
Topics: Adult; Aged; Area Under Curve; Carnitine; Citrulline; COVID-19; Female; Glutamic Acid; Humans; Kynurenine; Male; Metabolome; Metabolomics; Middle Aged; Ornithine; Risk Factors; ROC Curve; SARS-CoV-2; Severity of Illness Index; Tryptophan | 2021 |
Analysis of Serum Metabolomics in Rats with Osteoarthritis by Mass Spectrometry.
Topics: Animals; Biomarkers; Cartilage, Articular; Chromatography, Liquid; Collagenases; Disease Models, Animal; Fatty Acids; Glutamic Acid; Humans; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Nitrogen; Osteoarthritis; Rats; Spermidine; Tryptophan | 2021 |
Pigment epithelium-derived factor may induce antidepressant phenotypes in mice by the prefrontal cortex.
Topics: Adult; Animals; Depression; Down-Regulation; Eye Proteins; Female; Glutamic Acid; Humans; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Phenotype; Prefrontal Cortex; Serpins; Stress, Psychological; Tryptophan | 2022 |
Disturbance of neurotransmitter metabolism in drug-naïve, first-episode major depressive disorder: a comparative study on adult and adolescent cohorts.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Biomarkers; Depressive Disorder, Major; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Methoxyhydroxyphenylglycol; Neurotransmitter Agents; Norepinephrine; Serotonin; Tryptophan; Vanilmandelic Acid | 2022 |
Topics: Animals; Cognition; Diet; Dysbiosis; Gastrointestinal Microbiome; Glutamic Acid; Kynurenine; Lipopolysaccharides; Mice; Mice, Inbred C57BL; RNA, Ribosomal, 16S; Tryptophan | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
[Mechanism of Cordyceps militaris against non-small cell lung cancer: based on serum metabolomics].
Topics: Alanine; Animals; Arginine; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cordyceps; Glutamic Acid; Glutamine; Glyoxylates; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Nitrogen; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine | 2022 |
Involvement of kynurenine pathway between inflammation and glutamate in the underlying etiopathology of CUMS-induced depression mouse model.
Topics: Animals; Depression; Disease Models, Animal; Glutamic Acid; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Mice; Tryptophan | 2022 |
The Association between Macrosomia and Amino Acids' Levels in Maternal and Cord Sera: A Case-Control Study.
Topics: Alanine; Amino Acids; Arginine; Case-Control Studies; Chromatography, Liquid; Female; Fetal Macrosomia; Glutamic Acid; Glutamine; Histidine; Humans; Infant, Newborn; Leucine; Methionine; Tandem Mass Spectrometry; Threonine; Tryptophan; Valine | 2023 |
Metagenomics-based inference of microbial metabolism towards neuroactive amino acids and the response to antibiotics in piglet colon.
Topics: Amino Acids; Animals; Anti-Bacterial Agents; Colon; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenine; Putrescine; Swine; Transaminases; Tryptophan | 2023 |
Conservative Tryptophan Residue in the Vicinity of an Active Site of the M15 Family l,d-Peptidases: A Key Element in the Catalysis.
Topics: Catalysis; Catalytic Domain; Glutamic Acid; Peptide Hydrolases; Tryptophan | 2023 |
Photodissociative decay pathways of the flavin mononucleotide anion and its complexes with tryptophan and glutamic acid.
Topics: Anions; Flavin Mononucleotide; Glutamic Acid; Protons; Tryptophan | 2023 |