glutamic acid has been researched along with threonine in 226 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (9.29) | 18.7374 |
| 1990's | 67 (29.65) | 18.2507 |
| 2000's | 108 (47.79) | 29.6817 |
| 2010's | 24 (10.62) | 24.3611 |
| 2020's | 6 (2.65) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Hatano, M; Hiroya, K; Ishigooka, M; Shimizu, T | 1 |
| Caraceni, T; Fetoni, V; Girotti, F; Testa, D | 1 |
| Aulak, K; Bissler, J; Davis, AE; Eldering, E; Hack, CE; Kramer, J; Parad, RB; Rosen, FS; Stecklein, HP; Strunk, RC | 1 |
| Bowne, DB; Flores, E; Matthews, RJ; Thomas, ML | 1 |
| Behar, KL; Ogino, T | 1 |
| Bussolati, O; Dall'Asta, V; Gazzola, GC; Laris, PC; Rotoli, BM | 1 |
| Ishii, Y; Nishida, N; Sawai, T; Tachibana, K; Tsukamoto, K; Ujiie, K; Yamazaki, N | 1 |
| Kikura, R; Ohno, R; Sawai, T; Tsukamoto, K | 1 |
| Merz, KM | 1 |
| Sotiroudis, TG; Xenakis, A | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Cohen, FS; Cramer, WA; Nakazawa, A; Peterson, AA; Shirabe, K; Shiver, JW; Xu, S | 1 |
| Daly, MP; Demediuk, P; Faden, AI | 1 |
| Beale, D; Coadwell, J | 1 |
| Baine, RM; Benson, JM; Hine, TK; Johnson, MH; Jue, DL; Moo-Penn, WF; Swan, DC; Virshup, DM; Zinkham, WH | 1 |
| Christoph, G; Siman, R | 1 |
| Askanazi, J; Elwyn, DH; Gil, KM; Gump, FE; Kinney, JM; Starker, PM | 1 |
| Enomoto, T; Fukao, K; Ishikawa, A; Ishiyama, H; Iwasaki, Y; Okamura, T; Ozaki, A; Yamamoto, H | 1 |
| Kemp, BE; Michnoff, CH; Stull, JT | 1 |
| Bradford, HF; Young, AM | 1 |
| Mora, F; Peinado, JM | 1 |
| Rechsteiner, M; Rogers, S; Wells, R | 1 |
| Rechsteiner, M | 1 |
| Bradford, HF; Dhaliwal, DK; Druce, DP; Norris, PJ | 1 |
| Miller, RD; Morse, SA; Tesh, MJ | 1 |
| Jackson, S; Potter, LM; Stas, RJ | 1 |
| Bhatnagar, R; Chauhan, BS; Desai, NC; Garg, SP | 1 |
| Mora, F; Myers, RD; Peinado, JM | 1 |
| Coy, DH; Hirst, BH | 1 |
| Le Floc'h, N; Obled, C; Sève, B | 1 |
| Ferrer-Montiel, AV; Montal, M; Patten, CD; Planells-Cases, R | 1 |
| Haque, A; Khan, JK; Kuo, YH; Lambein, F | 1 |
| Li, ML; Stollar, V | 1 |
| Bolívar, M; Delgado, AV; Salcedo, J; Vera, P | 1 |
| Jetten, MS; Sinskey, AJ | 1 |
| Jonsson, BH; Liljas, A; Lindskog, S; Xue, Y | 1 |
| Castagné, V; Finot, PA; Maire, JC | 1 |
| Agarwalla, S; Balaram, P; Francis, VS; Gokhale, RS; Santi, DV | 1 |
| Barlow, JW; Curtis, AJ; George, PM; Scrimshaw, BJ; Stockigt, JR; Topliss, DJ | 1 |
| Bagley, CJ; Barry, SC; Cambareri, B; D'Andrea, R; Dottore, M; Goodall, GJ; Moretti, P; Phillips, J; Shannon, MF; Vadas, MA | 1 |
| Hatano, M; Murakami, Y; Shimizu, T | 1 |
| Hatano, M; Hiroya, K; Murakami, Y; Ortiz de Montellano, PR; Shimizu, T | 1 |
| Ahlman, B; Andersson, K; Hedenborg, L; Leijonmarck, CE; Ljungqvist, O; Wernerman, J | 1 |
| Ahrens, F; Mosenthin, R; Sauer, WC | 1 |
| Henry, Y; le Floc'h, N; Sève, B | 1 |
| Fersht, AR; Jackson, SE | 1 |
| Curran, TP; Riordan, JF; Shapiro, R | 1 |
| Hatano, M; Hiroya, K; Ortiz de Montellano, PR; Shimizu, T; Tuck, SF | 1 |
| Fedele, E; Foster, AC | 1 |
| Chevaillier, P | 1 |
| Aleshin, AE; Fromm, HJ; Honzatko, RB; Shyur, LF | 1 |
| Barnes, JA; Gomes, AV | 1 |
| Frank, JS; Hryshko, LV; Matsuoka, S; Nicoll, DA; Philipson, KD | 1 |
| Bullock, R; Harms, JF; Tsuchida, E; Woodward, JJ | 1 |
| Rechsteiner, M; Rogers, SW | 1 |
| Kawabata, S; Kohara, A; Nakanishi, S; Okada, M; Tsutsumi, R; Yamaguchi, T | 1 |
| Cheng, CC; Egashira, Y; Manabe, A; Ohta, T; Sanada, H | 1 |
| Franklin, RM; Graeser, R; Kappes, B | 1 |
| Silveira, LA; Smith, JL; Spudich, JA | 1 |
| Bellet, PS; Harris, BV; Keilson, LM; Simbartl, LA; Sprecher, DL; Stein, EA | 1 |
| Moriwaka, F | 1 |
| Hanscombe, O; O'Hare, P; O'Reilly, D | 1 |
| Moitra, J; Szilák, L; Vinson, C | 1 |
| Couvineau, A; Du, K; Laburthe, M; Nicole, P | 1 |
| Li, J; Lu, H; Sun, J | 1 |
| Belloni, E; Gaudenz, K; Muenke, M; Roessler, E; Scherer, SW; Tsui, LC; Vargas, F | 1 |
| Aman, MJ; Henkart, PA; Leonard, WJ; Nakajima, H; Noguchi, M; Sarin, A; Shores, EW | 1 |
| Bruneau, N; Fisher, EA; Lombardo, D; Nganga, A | 1 |
| Jordan, P; Karess, R | 1 |
| Hunter, T; Potter, LR | 3 |
| Cross, FR; Levine, K | 1 |
| Prüss, BM | 1 |
| Edara, S; Goodtzova, K; Kanugula, S; Pegg, AE | 1 |
| Kim, JJ; Kuroda, Y; Saijo, T; Tanaka, K | 1 |
| De Luca, V; Monda, M; Sullo, A; Viggiano, A | 1 |
| Clarke, SM; Eaton-Rye, JJ; Morgan, TR; Shand, JA | 1 |
| Bonn, G; Fiechtner, B; Glossmann, H; Huck, CW; Moebius, FF; Soellner, KE | 1 |
| Flor, PJ; Gasparini, F; Kuhn, R; Litschig, S; Pin, JP; Prézeau, L; Rueegg, D; Stoehr, N; Thomsen, C; Vranesic, I | 1 |
| Elsliger, MA; Hanson, GT; Kallio, K; Remington, SJ; Wachter, RM | 1 |
| Hurley, TD; Weiner, H | 1 |
| Carvalho, AL; Huganir, RL; Kameyama, K | 1 |
| Beachy, RN; Hosokawa, D; Kawakami, S; Okada, Y; Padgett, HS; Watanabe, Y | 1 |
| Hughes, MG; McAdoo, DJ; Robak, G; Xu, GY | 1 |
| Gromet-Elhanan, Z; Nathanson, L | 1 |
| Christian, FA; Jackson, RN; Tate, TM | 1 |
| Myers, MP; Stampe, P | 1 |
| Lacount, MW; Lebioda, L; Lewinski, K; Ortlund, E | 1 |
| Corzo, N; del Castillo, MD; Olano, A; Sanz, ML | 1 |
| Palmer, TM; Stiles, GL | 1 |
| Barrientes, S; Cooke, C; Goodrich, DW | 1 |
| Lallès, JP; Montagne, L; Toullec, R | 1 |
| Eswar, N; Ramakrishnan, C | 1 |
| Hiratake, J; Inoue, M; Kumagai, H; Sakata, K; Suzuki, H | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Fujii, Y; Furuichi, M; Nakabeppu, Y; Sekiguchi, M; Shimokawa, H | 1 |
| Balashov, SP; Ebrey, TG; Gennis, RB; Kandori, H; Maeda, A; Tomson, FL | 1 |
| Brandt, R; Eidenmüller, J; Fath, T; Hellwig, A; Reed, J; Sontag, E | 1 |
| Darden, TA; Gorokhov, A; Negishi, M; Pedersen, LC; Pedersen, LG; Perera, L | 1 |
| Bandyopadhyay, G; Farese, RV; Kanoh, Y; Sajan, MP; Standaert, ML | 1 |
| Caserta, MT; Wyrwicz, AM; Yao, FS | 1 |
| Agrawal, A; Greenhough, TJ; Shrive, AK; Volanakis, JE | 1 |
| Hisatomi, O; Imamoto, Y; Kataoka, M; Koshimizu, H; Mihara, K; Mizukami, T; Tokunaga, F; Tsujimoto, K | 1 |
| Eikmanns, BJ; Katsoulidis, E; Möckel, B; Peters-Wendisch, PG; Sahm, H; Schiel, B; Wendisch, VF | 1 |
| Farrens, DL; Janz, JM | 1 |
| De La Cruz, EM; Ostap, EM; Sweeney, HL | 1 |
| Klonowski, W | 1 |
| Chen, Y; Ghosh, G; Huxford, T; Malek, S | 1 |
| Anders, MW; Blackburn, AC; Board, PG; Coggan, M; Lantum, H; Parker, MW; Polekhina, G; Tzeng, HF | 1 |
| Arinaminpathy, Y; Biggin, PC; Sansom, MS | 1 |
| Sheibani, N; Sorenson, CM | 1 |
| Christensen, B; Jensen, NB; Nielsen, J; Villadsen, J | 1 |
| Bae, CD; Jeon, S; Kim, S; Kim, YS; Park, J; Park, JB; Suh, PG | 1 |
| Chen, H; Dong, LQ; He, H; Liu, F; Quon, MJ; Wick, KR; Wick, MJ | 1 |
| Dahiya, M; Dikshit, KL; Mande, SC; Rajamohan, G | 1 |
| Goto, N; Igarashi, T; Morisaki, H; Yamamoto, A | 1 |
| Barnett, ME; Zolkiewski, M | 1 |
| Chen, EY; Clarke, DM | 1 |
| Hori, M; Kitagawa, K; Kuwabara, K; Mabuchi, T; Matsumoto, M; Omura-Matsuoka, E; Sasaki, T; Sugiura, S; Takasawa, K; Tanaka, S | 1 |
| Amiraslanov, I; Chern, SS; Hsiao, YY; Leu, YJ; Liao, YD; Liaw, YC; Wang, SC | 1 |
| Agerholm-Larsen, B; Chen, W; Linsel-Nitschke, P; Martinez, LO; Silver, DL; Tall, AR; Wang, N | 1 |
| Gross, AK; Oprian, DD; Xie, G | 1 |
| Gross, AK; Oprian, DD; Rao, VR | 1 |
| Laskowski, M; Markley, JL; Qasim, MA; Song, J | 1 |
| Funahashi, HO; Kikuchi, A; Nakagawa, Y; Nakao, A; Sawada, M; Suda, N; Suzuki, M; Takami, Y; Yoshida, S | 1 |
| Galili, G; Zhu, X | 1 |
| Elce, JS; Huynh, KK; Jia, Z; Smith, SD; Wells, A | 1 |
| Clark, S; Leever, JD; Partin, KM; Weeks, AM | 1 |
| Fukui, R; Higashi, H; Matsuyama, S; Nishi, A | 1 |
| FELSING, B; RAVEL, JM; SHIVE, W | 1 |
| BILINSKI, E; MCCONNELL, WB | 1 |
| Bryksa, BC; Tanaka, T; Yada, RY | 1 |
| Dodson, H; Earnshaw, WC; Henzing, AJ; Khaled, W; Wheatley, SP | 1 |
| Bottoni, A; Lanza, CZ; Miscione, GP; Spinelli, D | 1 |
| Fukui, M; Grenier, D; Hinode, D; Mayrand, D; Yoshioka, M | 1 |
| El-Mashtoly, SF; Fujiwara, K; Hamada, N; Imamoto, Y; Kataoka, M; Kumauchi, M; Sasaki, J; Tokunaga, F; Unno, M; Yamauchi, S | 1 |
| Crawford, E; Hendzel, MJ; Lever, MA; Th'ng, JP | 1 |
| Chen, PE; Johnston, AR; Mok, MH; Schoepfer, R; Wyllie, DJ | 1 |
| Du, GG; Guo, X; Khanna, VK; MacLennan, DH | 1 |
| Fujishiro, M; Goshima, Y; Ishii, T; Kitamura, H; Masuda, M; Matsuse, T; Teramoto, S | 1 |
| Kakihana, K; Kurosu, T; Miura, O; Mizuchi, D; Yamamoto, M | 1 |
| Dowling, M; Kao, GD; Liu, F; Yang, XJ | 1 |
| Escovar-Kousen, J; Irwin, DC; Wilson, DB; Zhou, W | 1 |
| Dilmac, N; Hilliard, N; Hockerman, GH | 1 |
| Clarkson, J; Shu, JC; Yudkin, MD | 1 |
| Adachi, M; Hirata, A; Mikami, B; Utsumi, S | 1 |
| Dahlin-Huppe, K; Fukushi, J; Makagiansar, IT; Mustelin, T; Stallcup, WB; Williams, S | 1 |
| Kolb, A; Lacour, S; Landini, P; Leroy, O | 1 |
| Blanco, J; Faehnle, CR; Viola, RE | 1 |
| André, B; Calderon, IL; Tenreiro, S; Velasco, I | 1 |
| Feng, L; Sheppard, K; Söll, D; Tumbula-Hansen, D | 1 |
| Opperdoes, FR; Tielens, AG; van Hellemond, JJ; van Weelden, SW | 1 |
| Bowness, P; di Gleria, K; Jones, EY; Kollnberger, S; McMichael, AJ; Stewart-Jones, GB | 1 |
| Agmon, N | 1 |
| Akana, J; Gerlt, JA; Rayment, I; Wise, EL; Yew, WS | 2 |
| Beck, SR; Bowden, DW; Burdon, KP; Freedman, BI; Langefeld, CD; Liu, Y; Rich, SS; Wagenknecht, LE | 1 |
| Imagawa, T; Kaya, S; Sakaguchi, K; Taniguchi, K; Yamamoto, T | 1 |
| Hosler, JP; Mills, DA | 1 |
| Bonanno, G; Giambelli, R; Musazzi, L; Popoli, M; Racagni, G; Raiteri, L; Raiteri, M; Tiraboschi, E; Zappettini, S | 1 |
| Chen, P; Harcum, SW | 1 |
| Koshland, DE; Kwan, G; Lu, CJ; Radisky, ES | 1 |
| Agarwal, R; Binz, T; Swaminathan, S | 1 |
| Kajikawa, H; Kurihara, M; Mitsumori, M; Tajima, K | 1 |
| Cheifetz, MN; Fridkin, M; Millar, RP; Naor, Z; Pawson, AJ; Shacham, S | 1 |
| Bittar, F; Bonnet, R; Chanal, C; Delmas, J; Robin, F | 1 |
| Biaggioni, I; Byrne, DW; Cascorbi, I; Garland, EM; Harris, PA; Jiang, L; Phillips, JA; Robertson, D; Rüdiger, H; Stanton, K; Williams, SM; Winker, R | 1 |
| Choi, CY; Kim, CH; Kim, EA; Kim, HT; Kim, YH; Lee, C; Lee, SE; Noh, YT; Ryu, MJ | 1 |
| Beau, F; Cuniasse, P; David, A; Devel, L; Dive, V; Makaritis, A; Rogakos, V; Yiotakis, A | 1 |
| Langer, I; Langlet, C; Nachtergael, I; Robberecht, P | 1 |
| Cater, MA; La Fontaine, S; Mercer, JF | 1 |
| Angel, C; Dobrovic, A; Dowling, JP; Kelly, JW; Liu, W; Magee, J; Mason, G; McArthur, GA; Murray, WK; Trivett, M; Wolfe, R | 1 |
| András, IE; Deli, MA; Hayashi, K; Hennig, B; Toborek, M; Veszelka, S | 1 |
| Yan, LX; Zhang, W; Zhu, FM | 1 |
| Colinet, H; Gagneul, D; Kostál, V; Lalouette, L; Renault, D | 1 |
| Burghardt, I; Cederbaum, LS; Gromov, EV; Köppel, H | 1 |
| Adeyeye, EI; Aluko, AO; Asaolu, SS | 1 |
| Alvarez-Arias, DA; Campbell, KS | 1 |
| Anderson, SM; Bass, CE; Cha, JH; Famous, KR; Kumaresan, V; Pierce, RC; Sadri-Vakili, G; Schmidt, HD; Terwilliger, EF | 1 |
| Gauld, JW; Robinet, JJ | 1 |
| Albitar, M; Cortes, J; Giles, F; Kantarjian, H; Lee, TS; Potts, SJ | 1 |
| Baldini, G; Bettati, S; Bosisio, C; Campanini, B; Chirico, G; Collini, M; D'Alfonso, L; Quercioli, V; Raboni, S | 1 |
| Akinshola, BE; Johnson, WD; Onaivi, ES; Parandaman, V; Taylor, RE | 1 |
| Funato, Y; Miki, H; Terabayashi, T | 1 |
| Galocha, B; García-Medel, N; Gómez, P; López de Castro, JA; Mavian, C | 1 |
| Cook, KE; Dall'acqua, WF; Damschroder, MM; Oganesyan, V; Woods, RM; Wu, H | 1 |
| Oja, SS; Saransaari, P | 1 |
| Drago, F; Frasca, A; Fumagalli, F; Pasini, M; Racagni, G; Riva, MA | 1 |
| Nickel, W; Pepperkok, R; Pietro, ES; Ritzerfeld, J; Schafmeier, T; Schulz, J; Smith, DF; Terjung, S; Tournaviti, S; Wegehingel, S | 1 |
| Becchi, M; Francina, A; Joly, P; Préhu, C; Riou, J; Wajcman, H; Zanella-Cleon, I | 1 |
| Bell, SD; Costa, A; Ioannou, C; Mogni, ME | 1 |
| Riemen, AJ; Waters, ML | 1 |
| Ahabrach, H; Boix, J; ElMlili, N; Errami, M; Felipo, V; Rodrigo, R | 1 |
| Bax, A; Bodner, CR; Dobson, CM; Maltsev, AS | 1 |
| Brautaset, T; Degnes, KF; Dillingham, R; Ellingsen, TE; Flickinger, MC; Jakobsen, ØM; Krog, A; Naerdal, I; Netzer, R | 1 |
| Aguilera, J; Barrera, I; Cid, L; Flores-Méndez, M; Hernández-Kelly, LC; Huerta, M; López-Bayghen, E; Ortega, A; Zinker, S | 1 |
| Esaki, N; Honda, A; Kurihara, T; Mihara, H; Omori, T | 1 |
| Busso, CS; Izumi, T; Wedgeworth, CM | 1 |
| Combs, B; Gamblin, TC; Voss, K | 1 |
| Bhowmik, AD; Chaudhuri, K; Mukherjee, S; Mukhopadhyay, K; Ray, JG; Roychoudhury, P | 1 |
| Erdődi, F; Kőszeghy, Á; Lontay, B; Pál, B; Rusznák, Z; Serfőző, Z; Szücs, G | 1 |
| Ehlers, MD; Kunz, PA; Kwon, H; Mabb, AM; Peixoto, RT; Philpot, BD; Sabatini, BL | 1 |
| Eidne, KA; Jaeger, WC; Pfleger, KD; Seeber, RM | 1 |
| Chaen, H; Fukuda, S; Fushinobu, S; Nishimoto, T; Okada, S; Wakagi, T; Watanabe, H; Yamamoto, T | 1 |
| Bahl, M; Barnes, T; Bell, K; Califaretti, N; Campbell, C; DiSebastiano, KM; Dubin, JA; Hanning, R; Mourtzakis, M; Russell, C; Vance, V | 1 |
| Hao, Y; Nair, SK; Ortega, MA; van der Donk, WA; Walker, MC; Zhang, Q | 1 |
| Balaram, H; Balaram, P; Bandyopadhyay, D; Murthy, MR | 1 |
| Barnes, T; Cybulak, K; Mastellar, SL; Urschel, KL | 1 |
| Bhattacharya, A; Bhattacharya, S; Patra, KK | 1 |
| Goonawardane, N; Harris, M; Ross-Thriepland, D | 1 |
| Donovan, MJ; Gietzen, DW; Lindström, SH; Sharp, JW; Teh, PS | 1 |
| Blacque, OE; Fujiwara, M; Hameed, S; Ikegami, K; Ishihara, T; Kaneko, T; Kaplan, OI; Kimura, Y; Konno, A; Setou, M; Teramoto, T; Tsutsumi, K | 1 |
| Jung, JH; Kim, YS; Lee, SM; Seo, JA | 1 |
| Kang, GY; Kim, KP; Lee, JW; Lee, N; Park, SH | 1 |
| Brimble, MA; Harris, PWR; Hermant, Y; Xu, B; Yang, SH | 1 |
| Mi, YY; Song, NH; Wang, ZJ; Yuan, W; Zhang, LF; Zhang, W; Zhu, LJ; Zuo, L | 1 |
| Alqhazo, M; Rashaid, AB | 1 |
| Emami Aleagha, MS; Mohammadi, P; Pashaei, S; Yarani, R | 1 |
| Curtis, GH; Hille, MB; Hirano, MS; Horton, EC; Huang, J; Kupai, A; Lackey, DL; Mathieson, CJ; Murayama, JF; Nakahara, H; Rodriguez, A; Shan, B; Voss, KM | 1 |
| Chen, L; Gu, J; Huang, C; Kong, Q; Lin, D; Lu, R; Wu, W | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Duan, Y; Lai, J; Li, L; Shao, L; Wang, J; Wang, Y; Xing, X; Yang, Z | 1 |
8 review(s) available for glutamic acid and threonine
| Article | Year |
|---|---|
Regulation of enzyme levels by proteolysis: the role of pest regions.
Topics: Amino Acid Sequence; Enzymes; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Proteins; Serine; Threonine | 1988 |
Recent advances in the physiology and genetics of amino acid-producing bacteria.
Topics: Amino Acids; Base Sequence; Cloning, Molecular; Corynebacterium; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Engineering; Glutamic Acid; Isoleucine; Lysine; Molecular Sequence Data; Threonine | 1995 |
Pest sequences in nuclear proteins.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Nuclear Proteins; Proline; Serine; Threonine | 1993 |
Mutagenesis studies of the cardiac Na(+)-Ca2+ exchanger.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Calcium; Carrier Proteins; Dogs; Glutamic Acid; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Serine; Sodium; Sodium-Calcium Exchanger; Structure-Activity Relationship; Threonine | 1996 |
PEST sequences and regulation by proteolysis.
Topics: Amino Acid Sequence; Glutamic Acid; Hydrolysis; Molecular Sequence Data; Proline; Proteins; Serine; Threonine | 1996 |
[Amyotrophic lateral sclerosis].
Topics: Adult; Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Animals; Autoimmunity; Double-Blind Method; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Nerve Growth Factors; Nerve Tissue Proteins; Point Mutation; Randomized Controlled Trials as Topic; Riluzole; Superoxide Dismutase; Thiazoles; Threonine | 1997 |
Non-equilibrium proteins.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cattle; Glutamic Acid; Humans; Macromolecular Substances; Models, Molecular; Models, Theoretical; Nitric Oxide; Prions; Proline; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Folding; Proteins; Rats; Serine; Structure-Activity Relationship; Threonine | 2001 |
The potential roles of amino acids and their major derivatives in the management of multiple sclerosis.
Topics: Amino Acids; Glutamic Acid; Humans; Multiple Sclerosis; Phenylalanine; Threonine; Tryptophan | 2022 |
1 trial(s) available for glutamic acid and threonine
| Article | Year |
|---|---|
Chronic treatment with L-threonine in amyotrophic lateral sclerosis: a pilot study.
Topics: Administration, Oral; Adult; Aged; Amyotrophic Lateral Sclerosis; Drug Administration Schedule; Female; Follow-Up Studies; Glutamates; Glutamic Acid; Glycine; Humans; Male; Middle Aged; Neurologic Examination; Receptors, N-Methyl-D-Aspartate; Threonine | 1992 |
217 other study(ies) available for glutamic acid and threonine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Role of Glu318 and Thr319 in the catalytic function of cytochrome P450d (P4501A2): effects of mutations on the methanol hydroxylation.
Topics: Amino Acid Sequence; Binding Sites; Cytochrome P-450 Enzyme System; Glutamates; Glutamic Acid; Hydroxylation; Kinetics; Methanol; Microsomes; Mutagenesis, Site-Directed; Oxygen Consumption; Recombinant Proteins; Saccharomyces cerevisiae; Threonine | 1992 |
C1 inhibitor hinge region mutations produce dysfunction by different mechanisms.
Topics: Alanine; Amino Acid Sequence; Angioedema; Animals; Base Sequence; Cell Line; Cells, Cultured; Codon; Complement C1 Inactivator Proteins; Complement C1s; Fibroblasts; Glutamates; Glutamic Acid; Heterozygote; Humans; Kallikreins; Molecular Sequence Data; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Threonine; Transfection; Valine | 1992 |
Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Blotting, Northern; Cell Line; Cloning, Molecular; DNA; Glutamates; Glutamic Acid; Hematopoietic Stem Cells; Histocompatibility Antigens; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Leukocyte Common Antigens; Male; Mice; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Organ Specificity; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; RNA; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; Substrate Specificity; Threonine | 1992 |
Assignment of resonance in the 1H spectrum of rat brain by two-dimensional shift correlated and J-resolved NMR spectroscopy.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Chromatography, Ion Exchange; Creatine; Electron Spin Resonance Spectroscopy; Female; Fourier Analysis; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Inositol; Lactates; Magnetic Resonance Spectroscopy; Rats; Rats, Inbred Strains; Taurine; Threonine | 1991 |
The preferential interaction of L-threonine with transport system ASC in cultured human fibroblasts.
Topics: Amino Acids; Arginine; Biological Transport; Cells, Cultured; Fibroblasts; Glutamates; Glutamic Acid; Humans; Kinetics; Male; Models, Biological; Skin; Sodium; Threonine | 1991 |
Role of lysine-67 in the active site of class C beta-lactamase from Citrobacter freundii GN346.
Topics: Amino Acid Sequence; Arginine; Base Sequence; beta-Lactamases; Binding Sites; Cephalosporinase; Citrobacter; Escherichia coli; Genes, Bacterial; Glutamates; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Protein Engineering; Restriction Mapping; RNA, Messenger; Threonine | 1990 |
Substitution of aspartic acid-217 of Citrobacter freundii cephalosporinase and properties of the mutant enzymes.
Topics: Aspartic Acid; beta-Lactamases; Cephalosporinase; Citrobacter; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glutamates; Glutamic Acid; Kinetics; Lysine; Mutation; Substrate Specificity; Threonine | 1990 |
Insights into the function of the zinc hydroxide-Thr199-Glu106 hydrogen bonding network in carbonic anhydrases.
Topics: Binding Sites; Carbonic Anhydrases; Computer Simulation; Glutamates; Glutamic Acid; Humans; Hydrogen Bonding; Hydroxides; Models, Molecular; Protein Conformation; Threonine; Zinc; Zinc Compounds | 1990 |
Pest sequences present in the subunits of phosphorylase kinase.
Topics: Amino Acid Sequence; Animals; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Muscles; Phosphorylase Kinase; Proline; Rabbits; Serine; Threonine | 1990 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Decrease of anion selectivity caused by mutation of Thr501 and Gly502 to Glu in the hydrophobic domain of the colicin E1 channel.
Topics: Amino Acid Sequence; Chlorides; Colicins; Escherichia coli; Glutamates; Glutamic Acid; Glycine; Kinetics; Lipid Bilayers; Membrane Potentials; Molecular Sequence Data; Mutation; Phosphatidylcholines; Phospholipids; Threonine | 1989 |
Effect of impact trauma on neurotransmitter and nonneurotransmitter amino acids in rat spinal cord.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Kinetics; Laminectomy; Male; N-Methylaspartate; Neurotransmitter Agents; Rats; Serine; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine | 1989 |
Some observations on conserved polar side chains in immunoglobulin V-domains.
Topics: Aspartic Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Hydrogen Bonding; Immunoglobulin Variable Region; Protein Conformation; Threonine; Tyrosine | 1989 |
Hb Catonsville (glutamic acid inserted between Pro-37(C2)alpha and Thr-38(C3)alpha). Nonallelic gene conversion in the globin system?
Topics: Alleles; Amino Acid Sequence; Base Sequence; Chromatography, High Pressure Liquid; Gene Conversion; Genes; Genetic Variation; Globins; Glutamates; Glutamic Acid; Hemoglobins, Abnormal; Humans; Molecular Sequence Data; Peptide Fragments; Polymerase Chain Reaction; Proline; Threonine; Trypsin | 1989 |
beta-Amyloid precursor is a PEST protein.
Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Brain Chemistry; Calpain; Glutamates; Glutamic Acid; Molecular Sequence Data; Proline; Protease Inhibitors; Protein Precursors; Rats; Serine; Threonine | 1989 |
Splanchnic substrate balance in malnourished patients during parenteral nutrition.
Topics: Adipose Tissue; Alanine; Amino Acids, Branched-Chain; Cystine; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Glutamates; Glutamic Acid; Glutamine; Glycine; Humans; Lipids; Liver; Male; Mesentery; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Protein Biosynthesis; Protein-Energy Malnutrition; Serine; Splanchnic Circulation; Threonine; Tyrosine | 1985 |
Hepatic coma and amino acids in the nerve endings of the central nervous system.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Glutamates; Glutamic Acid; Glycine; Hepatic Encephalopathy; Humans; In Vitro Techniques; Male; Nerve Endings; Neurotransmitter Agents; Potassium; Rats; Rats, Inbred Strains; Synaptosomes; Threonine | 1985 |
Phosphorylation of synthetic peptides by skeletal muscle myosin light chain kinases.
Topics: Alanine; Amino Acid Sequence; Animals; Chickens; Glutamates; Glutamic Acid; Kinetics; Myosin-Light-Chain Kinase; Oligopeptides; Protein Kinases; Rabbits; Threonine | 1986 |
Excitatory amino acid neurotransmitters in the corticostriate pathway: studies using intracerebral microdialysis in vivo.
Topics: Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Corpus Striatum; Dialysis; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Glycine; Male; Neurotransmitter Agents; Rats; Taurine; Threonine | 1986 |
Glutamic acid as a putative transmitter of the interhemispheric corticocortical connections in the rat.
Topics: Alanine; Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Male; Rats; Rats, Inbred Strains; Serine; Threonine | 1986 |
Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis.
Topics: Amino Acid Sequence; Caseins; Glutamates; Glutamic Acid; Half-Life; HeLa Cells; Humans; Proline; Proteins; Serine; Threonine | 1986 |
The suppression of stimulus-evoked release of amino acid neurotransmitters from synaptosomes by verapamil.
Topics: Amino Acids; Animals; Aspartic Acid; Biological Transport, Active; Calcium; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptosomes; Tetrodotoxin; Threonine; Verapamil; Veratridine | 1983 |
Intermediary metabolism in Legionella pneumophila: utilization of amino acids and other compounds as energy sources.
Topics: Acetates; Amino Acids; Carboxylic Acids; Glucose; Glutamates; Glutamic Acid; Lactates; Lactic Acid; Legionella; Oxygen Consumption; Pentosephosphates; Pyruvates; Pyruvic Acid; Serine; Threonine | 1983 |
Relative deficiencies of amino acids and nitrogen per se in low protein diets for young turkeys.
Topics: Amino Acids; Animals; Body Weight; Dietary Proteins; Female; Glutamates; Glutamic Acid; Lysine; Male; Nitrogen; Threonine; Turkeys; Valine | 1983 |
Study of the relationship between free amino acids and cataract in human lenses.
Topics: Adult; Aged; Alanine; Amino Acids; Cataract; Glutamates; Glutamic Acid; Glycine; Humans; Lens, Crystalline; Leucine; Middle Aged; Serine; Threonine | 1984 |
Symmetrical distribution of amino acid neurotransmitters in the right and left cerebral cortex of the rat.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glucose; Glutamates; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Serine; Threonine; Tissue Distribution | 1984 |
Structure-activity studies with somatostatin: role of lysine in positions 4 and 9 for gastric activity.
Topics: Animals; Cats; Gastric Acid; Gastric Mucosa; Glutamates; Glutamic Acid; Lysine; Somatostatin; Structure-Activity Relationship; Threonine | 1984 |
In vivo threonine oxidation rate is dependent on threonine dietary supply in growing pigs fed low to adequate levels.
Topics: Animals; Blood Glucose; Butyrates; Carbon Radioisotopes; Diet; Dose-Response Relationship, Drug; Eating; Female; Food, Fortified; Glucagon; Glutamic Acid; Glycine; Humans; Infusions, Intravenous; Insulin; Liver; Models, Biological; Oxidation-Reduction; Pancreas; Swine; Threonine | 1995 |
Mutation of conserved negatively charged residues in the S2 and S3 transmembrane segments of a mammalian K+ channel selectively modulates channel gating.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Brain; Conserved Sequence; Female; Glutamic Acid; Ion Channel Gating; Kinetics; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Protein Structure, Secondary; Recombinant Proteins; Threonine; Xenopus laevis | 1995 |
Inhibitory and excitatory amino acids in cerebrospinal fluid of neurolathyrism patients, a highly prevalent motorneurone disease.
Topics: Adolescent; Adult; Aged; Alanine; Aspartic Acid; Eating; Excitatory Amino Acids; Fabaceae; Glutamic Acid; Glycine; Humans; Isoleucine; Middle Aged; Motor Neuron Disease; Neurotoxins; Plants, Medicinal; Taurine; Threonine | 1995 |
A mutant of Sindbis virus which is released efficiently from cells maintained in low ionic strength medium.
Topics: Animals; Cell Membrane; Cells, Cultured; Chick Embryo; Cricetinae; Culture Media; DNA Mutational Analysis; Fibroblasts; Genes, Viral; Glutamic Acid; Osmolar Concentration; Point Mutation; Sindbis Virus; Threonine; Viral Envelope Proteins; Viral Structural Proteins; Virus Cultivation | 1995 |
Effects of different amino acids on the electrical characteristics of pharmaceutical polymers.
Topics: Alanine; Amino Acids; Chemistry, Pharmaceutical; Electrophoresis; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Lysine; Polymers; Threonine | 1995 |
Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II.
Topics: Carbonic Anhydrases; Catalysis; Computer Simulation; Crystallography, X-Ray; Glutamates; Glutamic Acid; Humans; Hydrogen Bonding; Hydroxides; Models, Chemical; Models, Molecular; Mutagenesis; Protein Binding; Threonine; Zinc Compounds | 1993 |
Effects of diet-induced hyperthreoninemia. II). Tissue and extracellular amino acid levels in the brain.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Cerebral Cortex; Diet; Glutamates; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Threonine | 1994 |
Thermal stabilization of thymidylate synthase by engineering two disulfide bridges across the dimer interface.
Topics: Amino Acid Sequence; Circular Dichroism; Computer Graphics; Crystallography, X-Ray; Disulfides; Enzyme Stability; Glutamates; Glutamic Acid; Hot Temperature; Kinetics; Lacticaseibacillus casei; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Protein Engineering; Protein Structure, Secondary; Thermodynamics; Threonine; Thymidylate Synthase | 1994 |
Thyroxine binding by human transthyretin variants: mutations at position 119, but not position 54, increase thyroxine binding affinity.
Topics: Genetic Variation; Glutamates; Glutamic Acid; Glycine; Humans; Infant; Methionine; Methods; Mutation; Prealbumin; Protein Binding; Threonine; Thyroxine | 1994 |
Two contiguous residues in human interleukin-3, Asp21 and Glu22, selectively interact with the alpha- and beta-chains of its receptor and participate in function.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Cell Line; Cloning, Molecular; Glutamates; Glutamic Acid; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Interleukin-5; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Receptors, Interleukin-3; Restriction Mapping; Sequence Homology, Amino Acid; Threonine; Transfection | 1994 |
Glu318 and Thr319 mutations of cytochrome P450 1A2 remarkably enhance homolytic O-O cleavage of alkyl hydroperoxides. An optical absorption spectral study.
Topics: Alcohols; Benzene Derivatives; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Glutamates; Glutamic Acid; Hydrogen Peroxide; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Oxidoreductases; Peroxides; Saccharomyces cerevisiae; Spectrum Analysis; tert-Butylhydroperoxide; Threonine | 1994 |
Differential roles of Glu318 and Thr319 in cytochrome P450 1A2 catalysis supported by NADPH-cytochrome P450 reductase and tert-butyl hydroperoxide.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Glutamates; Glutamic Acid; Kinetics; Microsomes, Liver; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Peroxides; Rats; Recombinant Proteins; Saccharomyces cerevisiae; tert-Butylhydroperoxide; Threonine | 1994 |
Short-term starvation alters the free amino acid content of the human intestinal mucosa.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Asparagine; Colon; Duodenum; Food; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Intestinal Mucosa; Intestine, Large; Male; Starvation; Threonine; Time Factors | 1994 |
Dietary pectin's effect on ileal and fecal amino acid digestibility and exocrine pancreatic secretions in growing pigs.
Topics: alpha-Amylases; Amino Acids; Animals; Aspartic Acid; Dietary Fiber; Digestion; Feces; Glutamates; Glutamic Acid; Glycine; Ileum; Male; Pancreas; Pancreatic Juice; Pectins; Phenylalanine; Proline; Serine; Swine; Threonine; Trypsin; Valine | 1994 |
The addition of glutamic acid or protein to a threonine-deficient diet differentially affects growth performance and threonine dehydrogenase activity in fattening pigs.
Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Body Composition; Dietary Proteins; Eating; Female; Glutamic Acid; Liver; Swine; Threonine | 1994 |
Contribution of residues in the reactive site loop of chymotrypsin inhibitor 2 to protein stability and activity.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Chymotrypsin; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutation; Peptides; Plant Proteins; Protein Denaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Solanum tuberosum; Subtilisins; Thermodynamics; Threonine | 1994 |
Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis.
Topics: Angiogenesis Inducing Agents; Animals; Base Sequence; Chick Embryo; Glutamates; Glutamic Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Proteins; Ribonuclease, Pancreatic; Serine; Substrate Specificity; Threonine | 1993 |
The cytochrome P450 1A2 active site: topology and perturbations caused by glutamic acid-318 and threonine-319 mutations.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Glutamates; Glutamic Acid; Imines; Liver; Mutagenesis, Site-Directed; Oxidoreductases; Protein Conformation; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Threonine | 1993 |
An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum.
Topics: Amino Acids; Animals; Asparagine; Aspartic Acid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Male; Microinjections; Nerve Degeneration; Niacin; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serine; Threonine | 1993 |
Site-directed mutagenesis of residues at subunit interfaces of porcine fructose-1,6-bisphosphatase.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; DNA Primers; Fructose-Bisphosphatase; Glutamic Acid; Kinetics; Macromolecular Substances; Models, Molecular; Models, Theoretical; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Recombinant Proteins; Swine; Thermodynamics; Threonine | 1996 |
Pest sequences in EF-hand calcium-binding proteins.
Topics: Amino Acid Sequence; Calcium-Binding Proteins; Glutamic Acid; Helix-Loop-Helix Motifs; Molecular Sequence Data; Multigene Family; Proline; S100 Proteins; Serine; Threonine | 1995 |
A use-dependent sodium channel antagonist, 619C89, in reduction of ischemic brain damage and glutamate release after acute subdural hematoma in the rat.
Topics: Animals; Aspartic Acid; Brain Ischemia; Dialysis; Disease Models, Animal; Glutamic Acid; Hematoma, Subdural; Male; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Threonine | 1996 |
Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Aspartic Acid; Calcium; Cell Line; Glutamic Acid; GTP-Binding Proteins; Mice; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Threonine; Transfection | 1996 |
Dietary wheat gluten alleviates the elevation of serum transaminase activities in D-galactosamine-injected rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dietary Proteins; Galactosamine; Glutamic Acid; Glutens; Kinetics; Lysine; Male; Rats; Rats, Wistar; Threonine; Triticum; Uracil Nucleotides | 1996 |
Mechanisms of activation of the cdc2-related kinase PfPK5 from Plasmodium falciparum.
Topics: Animals; CDC2 Protein Kinase; Enzyme Activation; Glutamic Acid; Mutagenesis, Site-Directed; Plasmodium falciparum; Protozoan Proteins; Threonine | 1996 |
Activation of Dictyostelium myosin light chain kinase A by phosphorylation of Thr166.
Topics: Amino Acid Sequence; Animals; Concanavalin A; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Myosin-Light-Chain Kinase; Phosphates; Phosphorylation; Phosphothreonine; Recombinant Proteins; Sequence Analysis; Sequence Homology, Amino Acid; Threonine | 1996 |
Higher triglycerides, lower high-density lipoprotein cholesterol, and higher systolic blood pressure in lipoprotein lipase-deficient heterozygotes. A preliminary report.
Topics: Adult; Blood Pressure; Body Mass Index; Cholesterol, LDL; Exons; Genetic Carrier Screening; Glutamic Acid; Glycine; Humans; Hyperlipoproteinemia Type I; Isoleucine; Lipoprotein Lipase; Point Mutation; Systole; Threonine; Triglycerides; Tryptophan | 1996 |
A single serine residue at position 375 of VP16 is critical for complex assembly with Oct-1 and HCF and is a target of phosphorylation by casein kinase II.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Casein Kinase II; Consensus Sequence; COS Cells; DNA-Binding Proteins; Glutamic Acid; HeLa Cells; Herpes Simplex Virus Protein Vmw65; Host Cell Factor C1; Humans; Macromolecular Substances; Molecular Sequence Data; Octamer Transcription Factor-1; Phosphorylation; Protein Serine-Threonine Kinases; Serine; Threonine; Transcription Factors; Transcriptional Activation | 1997 |
Design of a leucine zipper coiled coil stabilized 1.4 kcal mol-1 by phosphorylation of a serine in the e position.
Topics: Amino Acid Sequence; Arginine; Avian Proteins; Basic-Leucine Zipper Transcription Factors; Carrier Proteins; Centrifugation, Isopycnic; Circular Dichroism; Cyclic AMP-Dependent Protein Kinases; DNA Probes; DNA-Binding Proteins; G-Box Binding Factors; Genes, Reporter; Glutamic Acid; Glycine; Hot Temperature; Leucine Zippers; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoproteins; Phosphorylation; Protein Binding; Protein Denaturation; Protein Engineering; Protein Structure, Secondary; Recombinant Proteins; Serine; Threonine; Transcription Factors; Transcriptional Activation; Transfection | 1997 |
[Directed mutagenesis of human recombinant receptors of vasoactive intestinal peptide of VIP1 and VIP2 type. Difference in structure-activity relationship].
Topics: Alanine; Binding Sites; Glutamic Acid; Humans; Isoleucine; Mutagenesis, Site-Directed; Receptors, Vasoactive Intestinal Peptide; Structure-Activity Relationship; Threonine | 1997 |
[Determination of serum free amino acids and ammonia in pregnant women with severe pregnancy induced hypertension].
Topics: Adult; Amino Acids; Ammonia; Eclampsia; Female; Glutamic Acid; Humans; Pre-Eclampsia; Pregnancy; Threonine | 1996 |
Mutations in the C-terminal domain of Sonic Hedgehog cause holoprosencephaly.
Topics: Alanine; Amino Acid Sequence; Animals; Cell Line, Transformed; DNA Mutational Analysis; Exons; Female; Genes, Dominant; Glutamic Acid; Glycine; Hedgehog Proteins; Holoprosencephaly; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Proteins; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Threonine; Trans-Activators; Valine | 1997 |
Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Calpain; CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Primers; Glutamic Acid; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Macromolecular Substances; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Cytokine; Recombinant Proteins; Sequence Alignment; Serine; Signal Transduction; Substrate Specificity; T-Lymphocytes; Threonine | 1997 |
O-Glycosylation of C-terminal tandem-repeated sequences regulates the secretion of rat pancreatic bile salt-dependent lipase.
Topics: Amino Acid Sequence; Animals; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; DNA Probes; Galactose; Glutamic Acid; Glycosylation; Kinetics; Lipase; Monensin; Pancreas; Peptide Fragments; Proline; Rats; Recombinant Proteins; Serine; Sterol Esterase; Threonine; Transfection | 1997 |
Myosin light chain-activating phosphorylation sites are required for oogenesis in Drosophila.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line, Transformed; Drosophila; Female; Gene Deletion; Glutamic Acid; Insect Proteins; Molecular Sequence Data; Myosin Light Chains; Oogenesis; Ovum; Phosphorylation; Serine; Threonine | 1997 |
Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Atrial Natriuretic Factor; Binding Sites; Cell Line; Enzyme Activation; Glutamic Acid; Guanylate Cyclase; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Octoxynol; Peptide Mapping; Phosphopeptides; Phosphorylation; Receptors, Atrial Natriuretic Factor; Sequence Homology, Amino Acid; Serine; Threonine; Transfection | 1998 |
Molecular evolution allows bypass of the requirement for activation loop phosphorylation of the Cdc28 cyclin-dependent kinase.
Topics: CDC28 Protein Kinase, S cerevisiae; Cell Cycle; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; Cyclins; Enzyme Activation; Evolution, Molecular; Fungal Proteins; Glutamic Acid; Mutagenesis; Periodicity; Phosphorylation; Protein Serine-Threonine Kinases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Suppression, Genetic; Threonine | 1998 |
Acetyl phosphate and the phosphorylation of OmpR are involved in the regulation of the cell division rate in Escherichia coli.
Topics: Acetates; Aspartic Acid; Bacterial Proteins; Carbon; Cell Division; Culture Media; Escherichia coli; Flagella; Glutamic Acid; Models, Biological; Mutation; Organophosphates; Phosphate Acetyltransferase; Phosphorylation; Serine; Signal Transduction; Threonine; Trans-Activators | 1998 |
Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
Topics: Alanine; Amino Acid Sequence; DNA Repair; DNA-Binding Proteins; Enzyme Activation; Glutamic Acid; Guanine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Phenylalanine; Protein Conformation; Recombinant Proteins; Threonine; Tyrosine | 1998 |
The roles of threonine-136 and glutamate-137 of human medium chain acyl-CoA dehydrogenase in FAD binding and peptide folding using site-directed mutagenesis: creation of an FAD-dependent mutant, T136D.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Alum Compounds; Amino Acid Substitution; Animals; Aspartic Acid; Chromatography, Gel; Enzyme Activation; Enzyme Stability; Escherichia coli; Flavin-Adenine Dinucleotide; Fractional Precipitation; Gene Expression Regulation, Bacterial; Glutamic Acid; Humans; Mitochondria, Liver; Models, Molecular; Mutagenesis, Site-Directed; Protein Binding; Protein Folding; Protein Processing, Post-Translational; Rats; Riboflavin; Subcellular Fractions; Temperature; Threonine | 1998 |
Nitric oxide reduces hypophagia induced by threonine free diet in the rat.
Topics: Animals; Arginine; Aspartic Acid; Body Weight; Diet; Eating; Feeding Behavior; Glutamic Acid; Injections, Intraventricular; Male; Nitric Oxide; Nitroprusside; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents; Threonine | 1998 |
Specific requirements for cytochrome c-550 and the manganese-stabilizing protein in photoautotrophic strains of Synechocystis sp. PCC 6803 with mutations in the domain Gly-351 to Thr-436 of the chlorophyll-binding protein CP47.
Topics: Amino Acid Sequence; Amino Acid Substitution; Calcium; Chlorides; Chlorophyll; Culture Media, Conditioned; Cyanobacteria; Cytochrome c Group; Glutamic Acid; Glutamine; Glycine; Leucine; Light-Harvesting Protein Complexes; Manganese; Metalloproteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Photosynthesis; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Proteins; Threonine | 1998 |
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Asparagine; Carrier Proteins; Cell Membrane; Glutamic Acid; Histidine; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Threonine; Tryptophan | 1999 |
CPCCOEt, a noncompetitive metabotropic glutamate receptor 1 antagonist, inhibits receptor signaling without affecting glutamate binding.
Topics: Alanine; Amino Acid Sequence; Animals; CHO Cells; Chromones; COS Cells; Cricetinae; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Signal Transduction; Threonine | 1999 |
Structural and spectral response of green fluorescent protein variants to changes in pH.
Topics: Amino Acid Substitution; Animals; Crystallography, X-Ray; Glutamic Acid; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Luminescent Proteins; Mutagenesis, Site-Directed; Pigments, Biological; Protons; Scyphozoa; Serine; Spectrometry, Fluorescence; Structure-Activity Relationship; Threonine | 1999 |
Evaluation of the roles of the conserved residues of aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Amino Acid Sequence; Arginine; Binding Sites; Conserved Sequence; Glutamic Acid; Humans; Kinetics; Mutagenesis; NAD; Recombinant Fusion Proteins; Serine; Threonine | 1999 |
A constitutively "phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization.
Topics: Adenine; Amino Acid Sequence; Amino Acid Substitution; Atrial Natriuretic Factor; Enzyme Inhibitors; Glutamic Acid; Guanylate Cyclase; Humans; Microcystins; Molecular Sequence Data; Mutation; Peptides, Cyclic; Phosphorylation; Receptors, Atrial Natriuretic Factor; Recombinant Proteins; Serine; Threonine | 1999 |
Characterization of phosphorylation sites on the glutamate receptor 4 subunit of the AMPA receptors.
Topics: Amino Acid Sequence; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epithelial Cells; Glutamic Acid; Humans; Kidney; Molecular Sequence Data; Mutagenesis; Phosphorylation; Protein Kinase C; Receptors, AMPA; Synaptic Transmission; Threonine; Transfection | 1999 |
Phosphorylation and/or presence of serine 37 in the movement protein of tomato mosaic tobamovirus is essential for intracellular localization and stability in vivo.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Fluorescence; Glutamic Acid; Green Fluorescent Proteins; Intracellular Fluid; Luminescent Proteins; Molecular Sequence Data; Mutagenesis; Nicotiana; Phosphoamino Acids; Phosphorylation; Plant Viral Movement Proteins; Plants, Toxic; Protoplasts; Recombinant Fusion Proteins; Serine; Solanum lycopersicum; Threonine; Tobamovirus; Viral Proteins | 1999 |
Changes in amino acid concentrations over time and space around an impact injury and their diffusion through the rat spinal cord.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Citrulline; Glutamic Acid; Glycine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Taurine; Threonine; Time Factors | 1999 |
Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Cell Line; Glutamic Acid; Guanylate Cyclase; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphoproteins; Phosphorylation; Receptors, Atrial Natriuretic Factor; Recombinant Proteins; Serine; Threonine | 1999 |
Mutations in the beta-subunit Thr(159) and Glu(184) of the Rhodospirillum rubrum F(0)F(1) ATP synthase reveal differences in ligands for the coupled Mg(2+)- and decoupled Ca(2+)-dependent F(0)F(1) activities.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Calcium; Calcium-Transporting ATPases; Glutamic Acid; Ligands; Magnesium; Magnesium Chloride; Mutagenesis, Site-Directed; Protein Structure, Quaternary; Proton-Translocating ATPases; Recombinant Proteins; Rhodospirillum rubrum; Threonine | 2000 |
Effects of glyphosate and dalapon on total free amino acid profiles of Pseudosuccinea columella snails.
Topics: Alanine; Amino Acids; Animals; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Glyphosate; Herbicides; Propionates; Serine; Snails; Threonine | 2000 |
A point mutation in the maxi-K clone dSlo forms a high affinity site for charybdotoxin.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Charybdotoxin; Cloning, Molecular; COS Cells; Electrophysiology; Glutamic Acid; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Point Mutation; Potassium Channels; Potassium Channels, Calcium-Activated; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Threonine; Transfection | 2000 |
Reactions of Pseudomonas 7A glutaminase-asparaginase with diazo analogues of glutamine and asparagine result in unexpected covalent inhibitions and suggests an unusual catalytic triad Thr-Tyr-Glu.
Topics: Amidohydrolases; Aminolevulinic Acid; Asparagine; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diazooxonorleucine; Electrons; Enzyme Inhibitors; Glutamic Acid; Glutamine; Pseudomonas; Threonine; Tyrosine | 2000 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A(3) adenosine receptor.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; CHO Cells; Cricetinae; Cysteine; Glutamic Acid; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphorylation; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Threonine | 2000 |
Glutamic acid mutagenesis of retinoblastoma protein phosphorylation sites has diverse effects on function.
Topics: Bone Neoplasms; Cell Cycle; Cell Line; Cyclin-Dependent Kinases; Genes, Retinoblastoma; Glutamic Acid; Humans; Kidney; Mutagenesis, Site-Directed; Osteosarcoma; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Retinoblastoma Protein; Serine; Structure-Activity Relationship; Threonine; Transfection; Tumor Cells, Cultured | 2000 |
Calf intestinal mucin: isolation, partial characterization, and measurement in ileal digesta with an enzyme-linked immunosorbent assay.
Topics: Abomasum; Animals; Antibody Specificity; Aspartic Acid; Carbohydrates; Cattle; Centrifugation, Density Gradient; Cesium; Chlorides; Diet; Digestion; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Ileum; Immune Sera; Intestines; Milk; Mucins; Serine; Threonine | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Identification of catalytic nucleophile of Escherichia coli gamma-glutamyltranspeptidase by gamma-monofluorophosphono derivative of glutamic acid: N-terminal thr-391 in small subunit is the nucleophile.
Topics: Aminobutyrates; Catalysis; Enzyme Inhibitors; Escherichia coli; gamma-Glutamyltransferase; Glutamic Acid; Mass Spectrometry; Threonine | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Bacterial Proteins; Base Sequence; Catalytic Domain; Codon; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Glycine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoric Monoester Hydrolases; Pyrophosphatases; Suppression, Genetic; Threonine | 2000 |
Relocation of internal bound water in bacteriorhodopsin during the photoreaction of M at low temperatures: an FTIR study.
Topics: Aspartic Acid; Bacteriorhodopsins; Cell Polarity; Glutamic Acid; Halobacterium; Mutation; Proton Pumps; Retinaldehyde; Schiff Bases; Spectroscopy, Fourier Transform Infrared; Threonine; Valine; Water | 2000 |
Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins.
Topics: Actin Cytoskeleton; Adult; Amino Acid Sequence; Amino Acid Substitution; Glutamic Acid; Humans; Microtubules; Molecular Mimicry; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Phosphorylation; Polymerase Chain Reaction; Protein Conformation; Protein Phosphatase 2; Serine; Structure-Activity Relationship; tau Proteins; Threonine | 2000 |
Heparan sulfate biosynthesis: a theoretical study of the initial sulfation step by N-deacetylase/N-sulfotransferase.
Topics: Amidohydrolases; Amino Acid Sequence; Catalytic Domain; Crystallography, X-Ray; Glutamic Acid; Heparitin Sulfate; Kinetics; Lysine; Molecular Sequence Data; Sequence Alignment; Sequence Homology, Amino Acid; Sulfotransferases; Threonine | 2000 |
Insulin and PIP3 activate PKC-zeta by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adipocytes; Amino Acid Substitution; Animals; Enzyme Activation; Glutamic Acid; Insulin; Isoenzymes; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sequence Deletion; Substrate Specificity; Threonine; Transfection | 2001 |
In vitro 1H and 31P NMR spectroscopic evidence of multiple aberrant biochemical pathways in murine trisomy 16 brain development.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Choline; Creatine; Disease Models, Animal; Down Syndrome; Female; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phosphorus Isotopes; Protons; Taurine; Threonine | 2000 |
Topology and structure of the C1q-binding site on C-reactive protein.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; C-Reactive Protein; Complement Activation; Complement C1q; Glutamic Acid; Histidine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylcholine; Polysaccharides, Bacterial; Serum Albumin, Bovine; Streptococcus pneumoniae; Threonine; Tyrosine | 2001 |
Roles of amino acid residues near the chromophore of photoactive yellow protein.
Topics: Amino Acids; Bacterial Proteins; Glutamic Acid; Halorhodospira halophila; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Photolysis; Photoreceptors, Microbial; Protons; Spectrophotometry; Threonine; Titrimetry; Tyrosine | 2001 |
Pyruvate carboxylase is a major bottleneck for glutamate and lysine production by Corynebacterium glutamicum.
Topics: Corynebacterium; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Phosphoenolpyruvate Carboxylase; Plasmids; Pyruvate Carboxylase; Recombinant Proteins; Restriction Mapping; Species Specificity; Threonine | 2001 |
Engineering a functional blue-wavelength-shifted rhodopsin mutant.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; COS Cells; Glutamic Acid; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Photochemistry; Retinaldehyde; Rhodopsin; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thermodynamics; Threonine; Transducin | 2001 |
Kinetic mechanism and regulation of myosin VI.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Substitution; Animals; Glutamic Acid; Kinetics; Myosin Heavy Chains; Protein Binding; Pyrenes; Spectrometry, Fluorescence; Swine; Threonine | 2001 |
IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells.
Topics: Animals; Binding, Competitive; Cell Line; Cell Nucleus; Cloning, Molecular; Cytoplasm; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glutamic Acid; HeLa Cells; Humans; I-kappa B Proteins; Kinetics; Mice; Microscopy, Fluorescence; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Localization Signals; Plasmids; Proline; Protein Binding; Serine; Signal Transduction; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2001 |
GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase.
Topics: Adolescent; Adult; Aged; Alleles; Amino Acid Substitution; Arginine; cis-trans-Isomerases; Female; Glutamic Acid; Glutathione Transferase; Glycine; Humans; Leucine; Lysine; Male; Methionine; Middle Aged; Proline; Threonine | 2001 |
Molecular dynamics simulations of the ligand-binding domain of the ionotropic glutamate receptor GluR2.
Topics: Algorithms; Apolipoprotein A-II; Binding Sites; Computer Simulation; Crystallography, X-Ray; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Kainic Acid; Ligands; Models, Molecular; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, AMPA; Threonine; Time Factors | 2002 |
Altered regulation of SHP-2 and PTP 1B tyrosine phosphatases in cystic kidneys from bcl-2 -/- mice.
Topics: Animals; Cell Differentiation; Cytoskeletal Proteins; Epithelial Cells; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Enzymologic; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Kidney Diseases, Cystic; Leukemia, B-Cell; Lymphoma, B-Cell; Male; Mice; Mice, Mutant Strains; Paxillin; Phosphoproteins; Phosphorylation; Pregnancy; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-bcl-2; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Threonine | 2002 |
The simultaneous biosynthesis and uptake of amino acids by Lactococcus lactis studied by (13)C-labeling experiments.
Topics: Alanine; Amino Acids; Aspartic Acid; Biomass; Cell Membrane; Computer Simulation; Culture Media; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Isotope Labeling; Lactococcus lactis; Models, Biological; Models, Chemical; Phenylalanine; Threonine | 2002 |
RhoA and Rho kinase-dependent phosphorylation of moesin at Thr-558 in hippocampal neuronal cells by glutamate.
Topics: Animals; Brain; cdc42 GTP-Binding Protein; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Electroshock; Glutamic Acid; Hippocampus; Immunoblotting; Intracellular Signaling Peptides and Proteins; Male; Microfilament Proteins; Neurons; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Recombinant Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subcellular Fractions; Threonine; Time Factors; Transfection | 2002 |
Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Binding Sites; Blotting, Western; Cell Line; CHO Cells; Cricetinae; DNA, Complementary; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Insulin; Mice; Mutagenesis, Site-Directed; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Serine; Threonine; Transfection | 2002 |
Function of the 90-loop (Thr90-Glu100) region of staphylokinase in plasminogen activation probed through site-directed mutagenesis and loop deletion.
Topics: Base Sequence; Catalysis; DNA Primers; Glutamic Acid; Humans; Metalloendopeptidases; Models, Molecular; Molecular Probes; Mutagenesis, Site-Directed; Plasminogen; Threonine | 2002 |
An essential amino acid residue for catalytic activity of the dextranase of Streptococcus mutans.
Topics: Amino Acid Sequence; Amino Acids, Essential; Asparagine; Aspartic Acid; Binding Sites; Dextranase; Glucosyltransferases; Glutamic Acid; Humans; Molecular Biology; Mutagenesis, Site-Directed; Sequence Analysis, Protein; Streptococcus; Streptococcus mutans; Streptococcus sobrinus; Threonine; Valine | 2002 |
Site-directed mutagenesis of conserved charged amino acid residues in ClpB from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Acidic; Amino Acids, Basic; Arginine; Conserved Sequence; Endopeptidase Clp; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Threonine | 2002 |
The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator.
Topics: Amino Acid Sequence; Amino Acids; Animals; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cystic Fibrosis Transmembrane Conductance Regulator; Glutamic Acid; Humans; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; Mutation; Plasmids; Proline; Proteasome Endopeptidase Complex; Protein Folding; Serine; Threonine; Transfection | 2002 |
Differential Akt phosphorylation at Ser473 and Thr308 in cultured neurons after exposure to glutamate in rats.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Glutamic Acid; Glycogen Synthase Kinase 3; In Vitro Techniques; Morpholines; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Threonine; Time Factors | 2002 |
Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography.
Topics: Amino Acid Sequence; Animals; Catalysis; Cell Survival; Circular Dichroism; Crystallography, X-Ray; DNA, Complementary; Genetic Vectors; Glutamic Acid; Guanine; Humans; Hydrogen; Kinetics; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Protein Structure, Tertiary; Rana catesbeiana; Recombinant Proteins; Ribonuclease, Pancreatic; Ribonucleases; RNA; Sequence Homology, Amino Acid; Substrate Specificity; Threonine | 2003 |
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I.
Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Calpain; Cell Line; Cell Membrane; Cells, Cultured; Chickens; Cholesterol; Cross-Linking Reagents; Dipeptides; DNA; Dose-Response Relationship, Drug; Endopeptidases; Glutamic Acid; Hepatocytes; Humans; Ligands; Lipid Metabolism; Macrophages; Mice; Molecular Sequence Data; Phospholipids; Plasmids; Proline; Serine; Threonine; Time Factors; Transfection; Up-Regulation | 2003 |
Slow binding of retinal to rhodopsin mutants G90D and T94D.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Glutamic Acid; Glutamine; Glycine; Humans; Molecular Sequence Data; Mutagenesis, Insertional; Night Blindness; Protein Binding; Protein Denaturation; Retinaldehyde; Rhodopsin; Schiff Bases; Spectrophotometry, Ultraviolet; Threonine | 2003 |
Characterization of rhodopsin congenital night blindness mutant T94I.
Topics: Amino Acid Sequence; Animals; Cattle; COS Cells; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Light; Molecular Sequence Data; Mutagenesis, Insertional; Night Blindness; Rhodopsin; Schiff Bases; Threonine; Transducin; Transfection | 2003 |
NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Genetic Variation; Glutamic Acid; Glycine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Ovomucin; Protein Conformation; Protein Structure, Tertiary; Serine Proteinase Inhibitors; Thermodynamics; Threonine; Titrimetry; Turkeys | 2003 |
Function of the loop residue Thr792 in human DNA topoisomerase II alpha.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Catalysis; Cell Division; Cysteine; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Fungal Proteins; Genetic Complementation Test; Glutamic Acid; Glycine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Poly-ADP-Ribose Binding Proteins; Saccharomyces cerevisiae; Serine; Threonine; Valine | 2003 |
Increased lysine synthesis coupled with a knockout of its catabolism synergistically boosts lysine content and also transregulates the metabolism of other amino acids in Arabidopsis seeds.
Topics: Amino Acids; Arabidopsis; Asparagine; Aspartic Acid; Bacteria; Bacterial Proteins; Gene Expression Regulation, Plant; Germination; Glutamic Acid; Glutamine; Hydro-Lyases; Lysine; Methionine; Mutation; Plants, Genetically Modified; Pterocarpans; Seeds; Signal Transduction; Threonine | 2003 |
Glutamate substitutions at a PKA consensus site are consistent with inactivation of calpain by phosphorylation.
Topics: Amino Acid Substitution; Animals; Calcium; Calpain; Consensus Sequence; Cyclic AMP-Dependent Protein Kinases; Enzyme Stability; Glutamic Acid; Mutation; Phosphorylation; Rats; Serine; Threonine | 2003 |
Identification of a site in GluR1 and GluR2 that is important for modulation of deactivation and desensitization.
Topics: Amino Acid Substitution; Animals; Benzothiadiazines; Binding Sites; Dioxoles; Glutamic Acid; Kinetics; Models, Molecular; Oocytes; Piperidines; Point Mutation; Receptors, AMPA; Serine; Threonine; Transfection; Xenopus laevis | 2003 |
Regulation of DARPP-32 Thr75 phosphorylation by neurotensin in neostriatal neurons: involvement of glutamate signalling.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Benzazepines; Dizocilpine Maleate; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Glutamic Acid; Histamine H1 Antagonists; Immunoblotting; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Neostriatum; Nerve Tissue Proteins; Neurons; Neurotensin; Phosphoproteins; Piperidines; Pyrazoles; Quinolines; Raclopride; Receptors, Neurotensin; Signal Transduction; Tetrodotoxin; Threonine; Time Factors | 2003 |
Glutamic acid inhibition of aspartic acid utilization in threonine biosynthesis.
Topics: Aspartic Acid; Glutamates; Glutamic Acid; Leuconostoc; Threonine | 1954 |
Studies on wheat plants using C14 compounds. IV. Distribution of C14 in glutamic acid, aspartic acid, and threonine arising from acetate-1-C14 and -2-C14.
Topics: Acetates; Aspartic Acid; Carbon; Dietary Fats, Unsaturated; Glutamic Acid; Metabolism; Plant Oils; Threonine; Triticum | 1957 |
N-terminal modifications increase the neutral-pH stability of pepsin.
Topics: Alanine; Amino Acid Substitution; Animals; Catalysis; Circular Dichroism; Enzyme Activation; Enzyme Stability; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Lysine; Mutagenesis, Site-Directed; Pepsin A; Pepsinogen A; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Swine; Threonine | 2003 |
Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo.
Topics: Amino Acid Sequence; Animals; Aurora Kinase B; Aurora Kinases; Cells, Cultured; Chromosomal Proteins, Non-Histone; Glutamic Acid; Glutathione Transferase; HeLa Cells; Humans; In Vitro Techniques; Inhibitor of Apoptosis Proteins; Mass Spectrometry; Metaphase; Microtubule-Associated Proteins; Molecular Sequence Data; Mutation; Neoplasm Proteins; Peptides; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Survivin; Threonine; Transfection | 2004 |
New model for a theoretical density functional theory investigation of the mechanism of the carbonic anhydrase: how does the internal bicarbonate rearrangement occur?
Topics: Bicarbonates; Carbonic Anhydrase II; Glutamic Acid; Models, Chemical; Models, Molecular; Thermodynamics; Threonine; Water; Zinc | 2004 |
Antigenic cross-reactivity and sequence homology between Actinobacillus actinomycetemcomitans GroEL protein and human fibronectin.
Topics: Aggregatibacter actinomycetemcomitans; Antibodies, Bacterial; Antibodies, Bispecific; Antibody Specificity; Antigens, Bacterial; Chaperonin 60; Collagen Type IV; Cross Reactions; Epitopes; Escherichia coli; Fibronectins; Glutamic Acid; Glutamine; Glycine; Humans; Isoleucine; Leucine; Sequence Homology, Amino Acid; Threonine | 2004 |
Resonance Raman spectroscopy reveals the origin of an intermediate wavelength form in photoactive yellow protein.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Deuterium Exchange Measurement; Glutamic Acid; Glutamine; Kinetics; Phenylalanine; Photoreceptors, Microbial; Quantum Theory; Recombinant Proteins; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Thermodynamics; Thiocyanates; Threonine; Tyrosine; Valine | 2004 |
The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatin; Gene Deletion; Glutamic Acid; Green Fluorescent Proteins; Histones; Humans; Kinetics; Luminescent Proteins; Lysine; Mice; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2004 |
Influence of a threonine residue in the S2 ligand binding domain in determining agonist potency and deactivation rate of recombinant NR1a/NR2D NMDA receptors.
Topics: Animals; Binding Sites; Glutamic Acid; Ion Channel Gating; Ligands; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Rats; Receptors, N-Methyl-D-Aspartate; Threonine; Xenopus laevis | 2004 |
Central core disease mutations R4892W, I4897T and G4898E in the ryanodine receptor isoform 1 reduce the Ca2+ sensitivity and amplitude of Ca2+-dependent Ca2+ release.
Topics: Adenosine Triphosphate; Arginine; Calcium; Calcium Isotopes; Calcium-Transporting ATPases; Cell Line; Glutamic Acid; Glycine; Humans; Isoleucine; Kidney; Microsomes; Mutagenesis, Site-Directed; Mutation, Missense; Myopathy, Central Core; Oxalates; Photometry; Protein Isoforms; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Threonine; Tryptophan | 2004 |
Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells.
Topics: Adenocarcinoma; Amino Acid Substitution; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Cytoplasm; Enzyme Inhibitors; Glutamic Acid; Humans; Lung Neoplasms; Phosphorylation; Serine; Threonine; Tissue Distribution; Tumor Suppressor Proteins | 2004 |
The two major imatinib resistance mutations E255K and T315I enhance the activity of BCR/ABL fusion kinase.
Topics: Animals; Antineoplastic Agents; Benzamides; Chlorocebus aethiops; COS Cells; DNA-Binding Proteins; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Glutamic Acid; Humans; Imatinib Mesylate; Leukemia; Milk Proteins; Mutation; Phosphorylation; Piperazines; Protein Structure, Tertiary; Pyrimidines; STAT5 Transcription Factor; Threonine; Trans-Activators | 2004 |
Caspase-mediated specific cleavage of human histone deacetylase 4.
Topics: Amino Acid Motifs; Animals; Apoptosis; Aspartic Acid; Binding Sites; Biological Transport; Caspase 3; Caspases; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Survival; CHO Cells; Cricetinae; Cycloheximide; Cysteine Endopeptidases; Dactinomycin; Doxycycline; Genetic Vectors; Glutamic Acid; HeLa Cells; Histone Deacetylases; Humans; Models, Biological; Multienzyme Complexes; Mutagenesis, Site-Directed; Proline; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Threonine; Time Factors; Ultraviolet Rays | 2004 |
Kinetic studies of Thermobifida fusca Cel9A active site mutant enzymes.
Topics: Actinomycetales; Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Carboxymethylcellulose Sodium; Cellulase; Enzyme Activation; Fibronectins; Glutamic Acid; Kinetics; Leucine; Lysine; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Deletion; Substrate Specificity; Threonine; Tyrosine | 2004 |
Molecular determinants of frequency dependence and Ca2+ potentiation of verapamil block in the pore region of Cav1.2.
Topics: Alanine; Amino Acid Substitution; Barium; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Drug Synergism; Glutamic Acid; Glutamine; Glycine; Humans; Kinetics; Mutation; Permeability; Phenylalanine; Threonine; Verapamil | 2004 |
Studies of SpoIIAB mutant proteins elucidate the mechanisms that regulate the developmental transcription factor sigmaF in Bacillus subtilis.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; Arginine; Bacillus subtilis; Bacterial Proteins; Glutamic Acid; Kinetics; Lysine; Multiprotein Complexes; Mutation; Nucleotides; Phenotype; Phosphorylation; Sigma Factor; Threonine | 2004 |
Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type.
Topics: Asparagine; Bacillus cereus; Bacterial Proteins; beta-Amylase; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Glutamic Acid; Glycine max; Hydrogen-Ion Concentration; Kinetics; Maltose; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Plant Proteins; Threonine; Tyrosine | 2004 |
Phosphorylation of NG2 proteoglycan by protein kinase C-alpha regulates polarized membrane distribution and cell motility.
Topics: Animals; Antigens; Binding Sites; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cytoplasm; Cytoskeletal Proteins; Glutamic Acid; Humans; Microscopy, Electron; Microscopy, Fluorescence; Mutation; Phorbol Esters; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Protein Structure, Tertiary; Proteoglycans; Rats; Threonine; Valine | 2004 |
Substitutions in region 2.4 of sigma70 allow recognition of the sigmaS-dependent aidB promoter.
Topics: Binding, Competitive; Deoxyribonuclease I; DNA; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Escherichia coli Proteins; Genetic Vectors; Glutamic Acid; Glutamine; Heparin; Mutation; Plasmids; Potassium Permanganate; Promoter Regions, Genetic; Protein Binding; Sigma Factor; Threonine; Transcription, Genetic | 2004 |
Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Topics: Anions; Arsenates; Aspartate-Semialdehyde Dehydrogenase; Binding Sites; Binding, Competitive; Catalysis; Glutamic Acid; Haemophilus influenzae; Hydrogen Bonding; Ions; Ligands; Models, Chemical; Models, Molecular; Oxygen; Periodic Acid; Protein Binding; Protein Conformation; Substrate Specificity; Threonine | 2004 |
Saccharomyces cerevisiae Aqr1 is an internal-membrane transporter involved in excretion of amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; beta-Galactosidase; Biological Transport; Cell Membrane; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endocytosis; Exocytosis; Gene Expression Regulation, Fungal; Genotype; Glutamic Acid; Green Fluorescent Proteins; Homoserine; Membrane Transport Proteins; Methylamines; Microscopy, Fluorescence; Models, Biological; Monocarboxylic Acid Transporters; Mutation; Oligonucleotides; Plasmids; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Threonine; Time Factors | 2004 |
Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase.
Topics: Adenosine Triphosphate; Ammonium Chloride; Archaea; Asparaginase; Aspartic Acid; Binding Sites; Chromatography, Thin Layer; Cloning, Molecular; Enzyme Activation; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hydrolysis; Lysine; Methanobacteriaceae; Models, Chemical; Mutation; Phosphorylation; Protein Biosynthesis; Protein Kinases; Pyrrolidonecarboxylic Acid; RNA, Transfer; RNA, Transfer, Gln; Threonine | 2005 |
New functions for parts of the Krebs cycle in procyclic Trypanosoma brucei, a cycle not operating as a cycle.
Topics: Adenosine Triphosphate; Animals; Biochemistry; Cell Line; Chromatography, High Pressure Liquid; Citric Acid Cycle; Cytosol; Energy Metabolism; Fatty Acids; Fermentation; Glucose; Glutamic Acid; Glycerol; Glycolysis; Models, Biological; Models, Chemical; Oxidation-Reduction; Oxygen; Proline; Substrate Specificity; Succinic Acid; Threonine; Time Factors; Trypanosoma brucei brucei | 2005 |
Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B*2705.
Topics: Arginine; Glutamic Acid; HLA-B27 Antigen; Humans; Immunodominant Epitopes; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Receptors, Immunologic; Receptors, KIR; Receptors, KIR3DL1; Threonine; Viral Proteins | 2005 |
Proton pathways in green fluorescence protein.
Topics: Animals; Aspartic Acid; Binding Sites; Biophysics; Crystallography, X-Ray; Cytoplasm; Databases, Protein; Glutamic Acid; Glutamine; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Light; Lysine; Models, Chemical; Models, Molecular; Mutation; Nitrogen; Point Mutation; Protein Conformation; Protons; Scyphozoa; Solvents; Spectrophotometry; Threonine; Time Factors; Tyrosine; Water; X-Rays | 2005 |
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
Topics: Alanine; Aldehyde-Lyases; Aldehydes; Amino Acid Substitution; Arginine; Aspartic Acid; Carboxy-Lyases; Catalysis; Decarboxylation; Enzyme Stability; Escherichia coli Proteins; Evolution, Molecular; Formaldehyde; Glutamic Acid; Histidine; Ketoses; Methylomonas; Orotidine-5'-Phosphate Decarboxylase; Ribulosephosphates; Stereoisomerism; Threonine; Valine | 2005 |
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Crystallography, X-Ray; Enzyme Activation; Escherichia coli Proteins; Evolution, Molecular; Glutamic Acid; Mutagenesis, Site-Directed; Orotidine-5'-Phosphate Decarboxylase; Ribulosephosphates; Substrate Specificity; Threonine | 2005 |
T-786C polymorphism of the endothelial nitric oxide synthase gene is associated with albuminuria in the diabetes heart study.
Topics: Aged; Albuminuria; Aspartic Acid; Creatinine; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exons; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Homozygote; Humans; Linkage Disequilibrium; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Odds Ratio; Polymorphism, Genetic; Promoter Regions, Genetic; Threonine | 2005 |
Thr-774 (transmembrane segment M5), Val-920 (M8), and Glu-954 (M9) are involved in Na+ transport, and Gln-923 (M8) is essential for Na,K-ATPase activity.
Topics: 4-Nitrophenylphosphatase; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Cations; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Glutamine; Green Fluorescent Proteins; HeLa Cells; Humans; Kinetics; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Ouabain; Oxygen; Phosphorylation; Potassium; Protein Conformation; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Threonine; Transfection; Valine | 2005 |
Slow proton transfer through the pathways for pumped protons in cytochrome c oxidase induces suicide inactivation of the enzyme.
Topics: Animals; Arachidonic Acid; Binding Sites; Catalysis; Electron Transport Complex IV; Enzyme Activation; Glutamic Acid; Horses; Hydrogen-Ion Concentration; Oxidation-Reduction; Protein Subunits; Proton Pumps; Rhodobacter sphaeroides; Surface Properties; Threonine | 2005 |
Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus.
Topics: Animals; Antidepressive Agents; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunoprecipitation; Ionomycin; Ionophores; Male; Munc18 Proteins; Phosphorylation; Potassium Chloride; Rats; Rats, Sprague-Dawley; SNARE Proteins; Synaptosomes; Syntaxin 1; Threonine; Time Factors | 2005 |
Effects of amino acid additions on ammonium stressed CHO cells.
Topics: Amino Acids; Animals; Cell Culture Techniques; Cell Size; CHO Cells; Cricetinae; Cricetulus; Culture Media; Glutamic Acid; Glycine; Glycosylation; Hydrogen-Ion Concentration; Lactic Acid; Proline; Quaternary Ammonium Compounds; Recombinant Proteins; Threonine; Tissue Plasminogen Activator | 2005 |
Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2.
Topics: Arginine; Bacillus; Crystallization; Crystallography, X-Ray; Glutamic Acid; Hordeum; Hydrogen Bonding; Hydrolysis; Methionine; Mutagenesis, Site-Directed; Peptides; Plant Proteins; Protein Binding; Serine; Serine Proteinase Inhibitors; Solvents; Structure-Activity Relationship; Subtilisins; Threonine | 2005 |
Analysis of active site residues of botulinum neurotoxin E by mutational, functional, and structural studies: Glu335Gln is an apoenzyme.
Topics: Alanine; Apoenzymes; Arginine; Asparagine; Binding Sites; Botulinum Toxins; Catalysis; Crystallization; Enzyme Activation; Glutamic Acid; Glutamine; Kinetics; Mutagenesis, Site-Directed; Neprilysin; Neurotoxins; Protease Inhibitors; Substrate Specificity; Thermolysin; Threonine; Tyrosine | 2005 |
Short communication: Amino acids antagonistic to the amino acids inhibitory for growth rate of mixed ruminal bacteria.
Topics: Amino Acids; Animals; Bacteria; Cattle; Diet; Feedback, Physiological; Female; Fermentation; Glutamic Acid; Isoleucine; Leucine; Nitrogen; Phenylalanine; Rumen; Threonine; Tryptophan; Tyrosine; Valine | 2005 |
Identification of Ser153 in ICL2 of the gonadotropin-releasing hormone (GnRH) receptor as a phosphorylation-independent site for inhibition of Gq coupling.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; COS Cells; DNA Primers; Epitopes; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gq-G11; Hydrolysis; Immunoblotting; Inositol Phosphates; Kinetics; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphorylation; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Receptors, LHRH; Serine; Threonine; Time Factors; Transfection | 2005 |
Unexpected enzyme TEM-126: role of mutation Asp179Glu.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Binding Sites; Ceftazidime; Conjugation, Genetic; Drug Resistance, Bacterial; Escherichia coli; Glutamic Acid; Hydrolysis; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Molecular Weight; Protein Binding; Protein Conformation; Protein Structure, Secondary; Sequence Analysis, DNA; Threonine | 2005 |
Endothelial NO synthase polymorphisms and postural tachycardia syndrome.
Topics: Adolescent; Adult; Alleles; Aspartic Acid; Case-Control Studies; Cysteine; Female; Genotype; Glutamic Acid; Heart Rate; Homozygote; Humans; Male; Middle Aged; Nitric Oxide Synthase Type III; Norepinephrine; Polymorphism, Genetic; Posture; Severity of Illness Index; Syndrome; Tachycardia; Threonine | 2005 |
Phosphorylation and transactivation of Pax6 by homeodomain-interacting protein kinase 2.
Topics: Alanine; Animals; Binding Sites; Carrier Proteins; Cell Line; Cell Line, Tumor; DNA Mutational Analysis; Eye Proteins; Glucagon; Glutamic Acid; Green Fluorescent Proteins; Homeodomain Proteins; Humans; Immunohistochemistry; Luciferases; Mass Spectrometry; Mice; Mutagenesis, Site-Directed; Mutation; p300-CBP Transcription Factors; Paired Box Transcription Factors; PAX6 Transcription Factor; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Transcription, Genetic; Transcriptional Activation; Transfection | 2006 |
Development of selective inhibitors and substrate of matrix metalloproteinase-12.
Topics: Drug Design; Enzyme Inhibitors; Glutamic Acid; Humans; Kinetics; Lysine; Matrix Metalloproteinase 12; Matrix Metalloproteinases; Metalloendopeptidases; Models, Chemical; Models, Molecular; Peptide Library; Peptides; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity; Threonine; Time Factors | 2006 |
Mutation of the phosphorylatable residue Thr429 in Glu of the human VPAC1 led to a constitutively desensitized receptor.
Topics: Adenylyl Cyclases; Animals; CHO Cells; Cricetinae; Glutamic Acid; Humans; Mutation; Peptides; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Receptors, Vasoactive Intestinal Polypeptide, Type I; Threonine | 2006 |
Copper binding to the N-terminal metal-binding sites or the CPC motif is not essential for copper-induced trafficking of the human Wilson protein (ATP7B).
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Binding Sites; Cation Transport Proteins; Copper; Copper-Transporting ATPases; Cysteine; DNA Primers; Glutamic Acid; Glycine; Hepatolenticular Degeneration; Humans; Models, Molecular; Oligopeptides; Polymerase Chain Reaction; Protein Conformation; Threonine | 2007 |
Distinct clinical and pathological features are associated with the BRAF(T1799A(V600E)) mutation in primary melanoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Child; Female; Gene Frequency; Glutamic Acid; Humans; Male; Melanoma; Middle Aged; Multivariate Analysis; Mutation; Pigmentation; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Threonine; Valine | 2007 |
The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells.
Topics: Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Dizocilpine Maleate; Endothelial Cells; Excitatory Amino Acid Antagonists; Glutamic Acid; Membrane Proteins; Occludin; Phosphorylation; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Threonine; Tyrosine | 2007 |
Sequence analysis of the novel allele HLA-B*5522 in the Chinese population.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Asian People; Base Sequence; Glutamic Acid; HLA-B Antigens; Humans; Living Donors; Molecular Sequence Data; Sequence Analysis, DNA; Threonine | 2007 |
Cold exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes.
Topics: Acclimatization; Alanine; Amino Acids; Amino Acids, Essential; Animals; Arginine; Body Temperature; Cold Temperature; Glucose; Glutamic Acid; Glutamine; Glycerol; Inositol; Lysine; Proline; Ribitol; Sorbitol; Survival Analysis; Temperature; Tenebrio; Threonine; Trehalose; Tropical Climate; Valine | 2007 |
Electronic structure of the PYP chromophore in its native protein environment.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cysteine; Glutamic Acid; Models, Molecular; Phenylalanine; Photoreceptors, Microbial; Threonine; Tyrosine; Valine | 2007 |
Amino acid composition of two masticatory nuts (Cola acuminata and Garcinia kola) and a snack nut (Anacardium occidentale).
Topics: Amino Acids; Amino Acids, Acidic; Amino Acids, Essential; Anacardium; Arginine; Aspartic Acid; Cola; Cystine; Garcinia kola; Glutamic Acid; Isoelectric Point; Nuts; Threonine; Valine | 2007 |
Protein kinase C regulates expression and function of inhibitory killer cell Ig-like receptors in NK cells.
Topics: Amino Acid Substitution; Casein Kinase II; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cytotoxicity, Immunologic; Down-Regulation; Glutamic Acid; Humans; Killer Cells, Natural; Phosphorylation; Protein Kinase C; Receptors, KIR; Receptors, KIR3DL1; Serine; Substrate Specificity; Threonine | 2007 |
CaMKII: a biochemical bridge linking accumbens dopamine and glutamate systems in cocaine seeking.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Cocaine-Related Disorders; Diltiazem; Dopamine; Dopamine Agonists; Dopamine Uptake Inhibitors; Glutamic Acid; Male; Nucleus Accumbens; Phosphorylation; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Synaptic Transmission; Threonine | 2008 |
DFT investigation on the mechanism of the deacetylation reaction catalyzed by LpxC.
Topics: Amidohydrolases; Binding Sites; Carbon; Catalysis; Computational Biology; Glutamic Acid; Histidine; Hydrogen Bonding; Hydroxylation; Models, Chemical; Nitrogen; Oxygen; Protons; Substrate Specificity; Thermodynamics; Threonine; Water; Zinc | 2008 |
Molecular basis explanation for imatinib resistance of BCR-ABL due to T315I and P-loop mutations from molecular dynamics simulations.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Benzamides; Computer Simulation; Crystallography; Drug Resistance, Neoplasm; Genes, abl; Glutamic Acid; Humans; Imatinib Mesylate; Isoleucine; Methionine; Models, Molecular; Molecular Biology; Mutation; Piperazines; Protein Kinase Inhibitors; Protein Structure, Secondary; Protein-Tyrosine Kinases; Pyrimidines; Static Electricity; Threonine | 2008 |
Protonation and conformational dynamics of GFP mutants by two-photon excitation fluorescence correlation spectroscopy.
Topics: Computer Simulation; Glutamic Acid; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Luminescent Agents; Mutation; Photons; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Threonine | 2008 |
Disruption of agonist and ligand activity in an AMPA glutamate receptor splice-variable domain deletion mutant.
Topics: Alanine; Amino Acid Sequence; Animals; Asparagine; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Larva; Leucine; Ligands; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Receptors, AMPA; Sequence Deletion; Threonine; Xenopus | 2008 |
Dishevelled-induced phosphorylation regulates membrane localization of Par1b.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cell Membrane; Dishevelled Proteins; Glutamic Acid; Humans; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Threonine | 2008 |
Presentation of cytosolically stable peptides by HLA-B27 is not dependent on the canonic interactions of N-terminal basic residues in the A pocket.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antigen Presentation; Cell Line, Tumor; Cytosol; Gene Expression Regulation; Glutamic Acid; HLA-B Antigens; HLA-B27 Antigen; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ligands; Peptide Fragments; Protein Binding; Serine; Signal Transduction; Thermodynamics; Threonine; Tryptophan | 2009 |
Structural characterization of a human Fc fragment engineered for extended serum half-life.
Topics: Animals; Cells, Cultured; Crystallography, X-Ray; Glutamic Acid; Half-Life; Histocompatibility Antigens Class I; Humans; Immunoglobulin Fc Fragments; Immunoglobulin G; Models, Molecular; Protein Conformation; Protein Engineering; Protein Stability; Rats; Receptors, Fc; Threonine; Tyrosine | 2009 |
Release of endogenous amino acids from the hippocampus and brain stem from developing and adult mice in ischemia.
Topics: Aging; Alanine; Animals; Aspartic Acid; Brain Ischemia; Brain Stem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Male; Mice; Potassium; Serine; Taurine; Threonine | 2009 |
Prenatal stress alters glutamatergic system responsiveness in adult rat prefrontal cortex.
Topics: Analysis of Variance; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Female; Glutamic Acid; Hippocampus; Male; Phosphorylation; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Restraint, Physical; Serine; Sex Factors; Stress, Psychological; Swimming; Threonine | 2009 |
Reversible phosphorylation as a molecular switch to regulate plasma membrane targeting of acylated SH4 domain proteins.
Topics: Animals; Antigens, Protozoan; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Endosomes; Enzyme Inhibitors; Glutamic Acid; Golgi Apparatus; Leishmania; Marine Toxins; Mutation; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins c-yes; Protozoan Proteins; Recombinant Fusion Proteins; RNA Interference; Threonine | 2009 |
Strategy for identification by mass spectrometry of a new human hemoglobin variant with two mutations in Cis in the beta-globin chain: Hb S-Clichy [beta6(A3)Glu-->Val; beta8(A5)Lys-->Thr].
Topics: Anemia, Sickle Cell; beta-Globins; Chromatography, Liquid; Female; Glutamic Acid; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Lysine; Mass Spectrometry; Middle Aged; Mutation; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Valine | 2009 |
The glutamate switch is present in all seven clades of AAA+ protein.
Topics: Adenosine Triphosphate; Amino Acid Motifs; Archaeal Proteins; Catalytic Domain; DnaB Helicases; Glutamic Acid; Minichromosome Maintenance 1 Protein; Multigene Family; Structural Homology, Protein; Substrate Specificity; Sulfolobus solfataricus; Threonine | 2009 |
Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan.
Topics: Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phosphorylation; Phosphoserine; Protein Folding; Protein Processing, Post-Translational; Serine; Threonine; Tryptophan; Tyrosine | 2009 |
Chronic hyperammonemia induces tonic activation of NMDA receptors in cerebellum.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebellum; Cyclic GMP; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperammonemia; In Vitro Techniques; Male; Microdialysis; Nitrates; Nitric Oxide Synthase Type I; Nitrites; Phosphorylation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine; Statistics, Nonparametric; Subcellular Fractions; Threonine | 2010 |
Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy.
Topics: Alanine; alpha-Synuclein; Genetic Variation; Glutamic Acid; Humans; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Parkinson Disease; Peptide Fragments; Phospholipids; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Solutions; Threonine | 2010 |
Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for L-lysine production from methanol at 50 degrees C.
Topics: Bacillus; Bacterial Proteins; Cloning, Molecular; Fermentation; Glutamic Acid; Homoserine Dehydrogenase; Hot Temperature; Lysine; Methanol; Methionine; Molecular Sequence Data; Mutation; Pyruvate Carboxylase; Threonine | 2010 |
Glutamate regulates eEF1A phosphorylation and ribosomal transit time in Bergmann glial cells.
Topics: Animals; Cell Communication; Cells, Cultured; Chick Embryo; Glutamic Acid; Neuroglia; Peptide Elongation Factor 1; Phosphorylation; Protein Biosynthesis; Protein Transport; Rats; Receptors, Glutamate; Ribosomes; Signal Transduction; Threonine; Time Factors; Tumor Cells, Cultured | 2010 |
Identification of novel mammalian phospholipids containing threonine, aspartate, and glutamate as the base moiety.
Topics: Animals; Aspartic Acid; Cerebrum; Chromatography, High Pressure Liquid; Glutamic Acid; Glycerophospholipids; Liver; Rats; Spectrometry, Mass, Electrospray Ionization; Swine; Tandem Mass Spectrometry; Threonine | 2011 |
Ubiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5.
Topics: Amino Acid Substitution; Animals; Cell Line; Cell Line, Tumor; Cyclin-Dependent Kinase 5; DNA-(Apurinic or Apyrimidinic Site) Lyase; Glutamic Acid; Humans; Lysine; Mice; Proto-Oncogene Proteins c-mdm2; Threonine; Ubiquitination | 2011 |
Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms.
Topics: Amino Acid Substitution; Arachidonic Acid; Aspartic Acid; Biopolymers; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mutagenesis, Site-Directed; Phosphorylation; Protein Isoforms; Serine; tau Proteins; Tauopathies; Threonine | 2011 |
Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population.
Topics: Adult; Areca; Arginine; Arylamine N-Acetyltransferase; Case-Control Studies; Codon; DNA Repair; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Glycine; Heterozygote; Homozygote; Humans; India; Lysine; Male; Methionine; Multifactor Dimensionality Reduction; Oral Submucous Fibrosis; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Tobacco, Smokeless; Tryptophan; X-ray Repair Cross Complementing Protein 1 | 2012 |
Protein phosphatase-1M and Rho-kinase affect exocytosis from cortical synaptosomes and influence neurotransmission at a glutamatergic giant synapse of the rat auditory system.
Topics: Animals; Animals, Newborn; Calcium; Cardiac Myosins; Cerebral Cortex; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Exocytosis; Female; Glutamic Acid; Immunoprecipitation; In Vitro Techniques; Male; Mass Spectrometry; Microscopy, Electron, Transmission; Myosin Light Chains; Patch-Clamp Techniques; Phosphorylation; Protein Binding; Protein Phosphatase 1; Qa-SNARE Proteins; Rats; Rats, Wistar; rho-Associated Kinases; Serine; Synapses; Synapsins; Synaptic Transmission; Synaptosomes; Threonine | 2012 |
Transsynaptic signaling by activity-dependent cleavage of neuroligin-1.
Topics: Animals; Animals, Newborn; Biotinylation; Calcium-Binding Proteins; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Dark Adaptation; Dendrites; Disease Models, Animal; Electric Stimulation; Electroporation; Enzyme Inhibitors; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; Luminescent Proteins; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Muscarinic Agonists; Mutation; Neural Cell Adhesion Molecules; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Photons; Pilocarpine; Plant Lectins; Potassium Chloride; Pregnancy; Pyridinium Compounds; Quaternary Ammonium Compounds; Red Fluorescent Protein; Signal Transduction; Status Epilepticus; Synaptic Transmission; Threonine; Transfection; Vesicular Glutamate Transport Protein 1 | 2012 |
Molecular determinants of orexin receptor-arrestin-ubiquitin complex formation.
Topics: Amino Acid Sequence; Arrestin; DNA, Complementary; Glutamic Acid; HEK293 Cells; Humans; Inositol Phosphates; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Mutagenesis; Neuropeptides; Orexin Receptors; Orexins; Serine; Threonine; Ubiquitin | 2014 |
Structural and mutational analysis of substrate recognition in kojibiose phosphorylase.
Topics: Amino Acid Substitution; Bacterial Proteins; Catalytic Domain; Disaccharides; Glucose; Glucosyltransferases; Glutamic Acid; Glycoside Hydrolases; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Phosphates; Protein Conformation; Recombinant Proteins; Substrate Specificity; Sulfates; Thermoanaerobacter; Threonine; Tryptophan; X-Ray Diffraction | 2014 |
Plasma amino acid profiles of breast cancer patients early in the trajectory of the disease differ from healthy comparison groups.
Topics: Adolescent; Adult; Amino Acids; Body Composition; Breast Neoplasms; Case-Control Studies; Energy Intake; Female; Glutamic Acid; Glutamine; Histidine; Humans; Leucine; Middle Aged; Threonine | 2014 |
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB.
Topics: Bacterial Proteins; Bacteriocins; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Hydro-Lyases; Lactococcus lactis; Membrane Proteins; Models, Molecular; Nisin; Phylogeny; Protein Structure, Tertiary; RNA, Transfer, Glu; Serine; Threonine | 2015 |
Probing the role of highly conserved residues in triosephosphate isomerase--analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzyme.
Topics: Amino Acid Sequence; Amino Acid Substitution; Biocatalysis; Conserved Sequence; Databases, Protein; Dimerization; Enzyme Stability; Glutamic Acid; Glutamine; Hot Temperature; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Plasmodium falciparum; Protein Conformation; Protozoan Proteins; Recombinant Proteins; Threonine; Triose-Phosphate Isomerase | 2015 |
Splanchnic extraction of phenylalanine in mature mares was not affected by threonine supplementation.
Topics: Animals; Dietary Supplements; Female; Glutamic Acid; Horses; Phenylalanine; Threonine; Viscera | 2016 |
Uncovering allostery and regulation in SAMHD1 through molecular dynamics simulations.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Substitution; Deoxyadenine Nucleotides; Glutamic Acid; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Molecular Dynamics Simulation; Monomeric GTP-Binding Proteins; Mutation; Phosphorylation; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Structure, Tertiary; SAM Domain and HD Domain-Containing Protein 1; Substrate Specificity; Threonine | 2017 |
Regulation of hepatitis C virus replication via threonine phosphorylation of the NS5A protein.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line, Tumor; Gene Expression Regulation, Viral; Glutamic Acid; HEK293 Cells; Hepacivirus; Hepatocytes; Host-Pathogen Interactions; Humans; Molecular Mimicry; Mutation; Phosphorylation; Plasmids; Threonine; Transfection; Viral Nonstructural Proteins; Virus Replication | 2018 |
Indispensable Amino Acid-Deficient Diets Induce Seizures in Ketogenic Diet-Fed Rodents, Demonstrating a Role for Amino Acid Balance in Dietary Treatments for Epilepsy.
Topics: Amino Acids, Essential; Animals; Brain; Deficiency Diseases; Diet, Ketogenic; Dietary Proteins; Epilepsy; Feeding Behavior; Female; Gerbillinae; Glutamic Acid; Male; Nutritional Requirements; Rats, Sprague-Dawley; Seizures; Threonine | 2018 |
Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Environment; Glutamic Acid; MAP Kinase Signaling System; Olfactory Receptor Neurons; p38 Mitogen-Activated Protein Kinases; Peptide Synthases; Phosphorylation; Protein Processing, Post-Translational; Threonine; Tubulin | 2018 |
Bioformation of Volatile and Nonvolatile Metabolites by
Topics: Acetates; Alanine; Carbon; Glutamic Acid; Glycine; Isoleucine; Mannitol; Mannose; Phenylacetates; Phenylalanine; Phenylethyl Alcohol; Proline; Saccharomycopsis; Serine; Sugar Alcohols; Threonine; Time Factors | 2018 |
Quantification of the Dynamic Phosphorylation Process of ERK Using Stable Isotope Dilution Selective Reaction Monitoring Mass Spectrometry.
Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; HeLa Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Mutation; PC12 Cells; Phosphorylation; Rats; Signal Transduction; Threonine; Tyrosine | 2019 |
A Versatile Boc Solid Phase Synthesis of Daptomycin and Analogues Using Site Specific, On-Resin Ozonolysis to Install the Kynurenine Residue.
Topics: Anti-Infective Agents; Daptomycin; Drug Evaluation, Preclinical; Glutamates; Glutamic Acid; Kynurenine; Ozone; Solid-Phase Synthesis Techniques; Staphylococcus aureus; Threonine | 2019 |
MMP-8 C-799 T, Lys460Thr, and Lys87Glu variants are not related to risk of cancer.
Topics: Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Matrix Metalloproteinase 8; Neoplasms; Polymorphism, Single Nucleotide; Threonine | 2019 |
Amino acids profiles of children who stutter compared to their fluent sibling.
Topics: Case-Control Studies; Child; Child, Preschool; Female; Glutamic Acid; Hair; Histidine; Humans; Isoleucine; Male; Siblings; Stuttering; Threonine; Tyrosine | 2020 |
Phosphorylation of serine residues S252, S268/S269, and S879 in p120 catenin activates migration of presomitic mesoderm in gastrulating zebrafish embryos.
Topics: Animals; Cadherins; Catenins; Glutamic Acid; Mesoderm; Mice; Phosphorylation; Serine; Threonine; Zebrafish | 2022 |
NMR-Based Metabolomic Analysis of Cardiac Tissues Clarifies Molecular Mechanisms of CVB3-Induced Viral Myocarditis and Dilated Cardiomyopathy.
Topics: Alanine; Animals; Aspartic Acid; Biomarkers; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Glutamic Acid; Glutamine; Glycine; Mice; Mice, Inbred BALB C; Myocarditis; Niacin; Niacinamide; Serine; Taurine; Threonine | 2022 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
The Association between Macrosomia and Amino Acids' Levels in Maternal and Cord Sera: A Case-Control Study.
Topics: Alanine; Amino Acids; Arginine; Case-Control Studies; Chromatography, Liquid; Female; Fetal Macrosomia; Glutamic Acid; Glutamine; Histidine; Humans; Infant, Newborn; Leucine; Methionine; Tandem Mass Spectrometry; Threonine; Tryptophan; Valine | 2023 |