glutamic acid and theanine

glutamic acid has been researched along with theanine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.86)18.2507
2000's11 (31.43)29.6817
2010's14 (40.00)24.3611
2020's9 (25.71)2.80

Authors

AuthorsStudies
Kobayashi, M; Yokogoshi, H1
Kakuda, T; Kataoka, K; Nozawa, A; Unno, T; Utsunomiya, K; Yanase, H1
Sadzuka, Y; Sonobe, T; Sugiyama, T; Tanaka, K1
Sadzuka, Y; Sonobe, T; Sugiyama, T; Suzuki, T1
Hayakawa, T; Kakuda, T; Sano, S; Tsuge, H; Unno, T1
Aoki, H; Fujimoto, S; Nagai, K; Nagasawa, K; Shimohama, S; Yasuda, E1
Sadzuka, Y; Sugiyama, T1
Juneja, LR; Okubo, T; Terashima, T; Yamada, T; Yokogoshi, H1
Juneja, LR; Kimura, K; Ohira, H; Ozeki, M1
Tachiki, T; Wakayama, M; Yamamoto, S1
Dimpfel, W; Kler, A; Kriesl, E; Lehnfeld, R1
Akiyama, Y; Arisaka, H; Kurihara, S; Shibahara, S1
Jiao, QC; Liu, JZ; Zhang, F; Zhao, GH; Zheng, QZ2
Chang, Y; Di, X; Shi, Z; Yan, J; Zhang, J; Zhao, B; Zhao, Y1
Loyens, E; Massie, A; Michotte, Y; Schallier, A; Smolders, I; Van Liefferinge, J; Vermoesen, K1
Hattori, K; Hori, H; Kunugi, H; Okubo, T; Ota, M; Ozawa, H; Sato, N; Teraishi, T; Wakabayashi, C1
Inoue, K; Min, JZ; Miyazaki, Y; Todoroki, K; Toyo'oka, T; Unno, K1
Kubota, Y; Shimazu, Y; Takeda, M; Takehana, S; Uotsu, N; Yui, K1
Bindal, S; Gupta, R; Sharma, S; Singh, TP1
Braidy, N; Daglia, M; Di Lorenzo, A; Khanjani, S; Moghaddam, AH; Nabavi, SF; Nabavi, SM; Sureda, A1
Abouazza, M; Barbanel, G; Bellahouel, S; Cens, T; Charnet, P; Cohen-Solal, C; de Jesus Ferreira, MC; Gratuze, M; Guiramand, J; Meusnier, C; Rolland, M; Rolland, V; Rousset, M; Sebih, F; Tassou, A; Vignes, M1
Cheng, S; Dong, F; Fu, X; Liao, Y; Wang, X; Yang, Z; Zeng, L1
Chen, Y; Gao, XB; Yang, W; Zhang, Y; Zhou, YF1
Cheng, S; Fu, X; Lai, J; Li, J; Liao, Y; Tang, J; Xu, X; Yang, Z; Zeng, L1
Bhattacharya, P; Borah, A; Deb, S; Dutta, A; Justin Thenmozhi, A; Manivasagam, T; Paul, R; Phukan, BC1
Cai, N; Chen, N; Fan, X; Li, Y; Ma, H; Ma, Q; Su, R; Wang, T; Xie, X; Xu, Q; Yuan, M; Zhang, C; Zhang, D; Zhao, G1
Jin, JM; Li, J; Qiu, Y; Shi, G; Tang, SY; Tao, Y; Xiong, D; Yao, J1
Kawada, K; Kuramoto, N; Mimori, S1
Cheng, S; Dong, F; Fu, X; Hao, X; Liao, Y; Wang, X; Xu, P; Xu, X; Yang, Z1
Chen, Y; Ferreira, JFDS; Gu, M; Huang, J; Liu, S; Liu, Z; Luo, Y; Tian, N; Xiao, L; Zhang, T; Zhang, X1
Cheng, S; Deng, R; Fu, X; Liao, Y; Yang, Z1
Chang, M; Chen, Q; Li, P; Li, Y; Li, Z; Liu, L; Peng, A; She, G; Shi, C; Sun, J; Wan, X; Yu, S; Zhao, J1
Akiyoshi, S; Harata, K; Kikuchi, H; Kuribayashi, F; Madhyastha, H; Sagara, T1
Awasthi, A; Kumar, S; Raj, K; Singh, S1

Reviews

2 review(s) available for glutamic acid and theanine

ArticleYear
Neuroprotective attributes of L-theanine, a bioactive amino acid of tea, and its potential role in Parkinson's disease therapeutics.
    Neurochemistry international, 2019, Volume: 129

    Topics: Animals; Brain; Glutamates; Glutamic Acid; Humans; Neuroprotective Agents; Neurotransmitter Agents; Parkinson Disease; Tea

2019
Possibility that the Onset of Autism Spectrum Disorder is Induced by Failure of the Glutamine-Glutamate Cycle.
    Current molecular pharmacology, 2021, Volume: 14, Issue:2

    Topics: Autism Spectrum Disorder; Brain; Endoplasmic Reticulum Stress; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Humans; Neurogenesis; Neuroglia; Neurons; Plant Extracts; Tea

2021

Trials

2 trial(s) available for glutamic acid and theanine

ArticleYear
L-Theanine reduces psychological and physiological stress responses.
    Biological psychology, 2007, Volume: 74, Issue:1

    Topics: Acute Disease; Adult; Brain; Cognition; Double-Blind Method; Electrocardiography; Female; Glutamates; Glutamic Acid; Heart Rate; Humans; Immunoglobulin A; Male; Neural Inhibition; Psychoneuroimmunology; Receptors, Glutamate; Saliva; Stress, Psychological; Sympathetic Nervous System

2007
Effect of L-theanine on glutamatergic function in patients with schizophrenia.
    Acta neuropsychiatrica, 2015, Volume: 27, Issue:5

    Topics: Adult; Antipsychotic Agents; Brain; Case-Control Studies; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Schizophrenia; Sleep; Treatment Outcome

2015

Other Studies

31 other study(ies) available for glutamic acid and theanine

ArticleYear
Hypotensive effect of gamma-glutamylmethylamide in spontaneously hypertensive rats.
    Life sciences, 1998, Volume: 62, Issue:12

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hypertension; Male; Rats; Rats, Inbred SHR; Tea

1998
Protective effect of gamma-glutamylethylamide (theanine) on ischemic delayed neuronal death in gerbils.
    Neuroscience letters, 2000, Aug-11, Volume: 289, Issue:3

    Topics: Animals; Brain Ischemia; Cell Count; Cell Death; Excitatory Amino Acid Antagonists; Gerbillinae; Glutamates; Glutamic Acid; Hippocampus; Nerve Degeneration; Neurons; Neuroprotective Agents; Reperfusion Injury

2000
Inhibition of glutamate transporter by theanine enhances the therapeutic efficacy of doxorubicin.
    Toxicology letters, 2001, Apr-30, Volume: 121, Issue:2

    Topics: 2-Aminoadipic Acid; Amino Acid Transport System X-AG; Antineoplastic Agents; ATP-Binding Cassette Transporters; Carbon Radioisotopes; Cell Membrane; Doxorubicin; Drug Synergism; Enzyme Inhibitors; Glutamates; Glutamic Acid; Humans; Kainic Acid; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

2001
Enhancement of the activity of doxorubicin by inhibition of glutamate transporter.
    Toxicology letters, 2001, Sep-15, Volume: 123, Issue:2-3

    Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Female; Glutamates; Glutamic Acid; Glutathione; Ketoprofen; Male; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Neoplasm Transplantation; Neoplasms, Experimental; RNA, Messenger; Sodium; Temperature; Tumor Cells, Cultured

2001
Theanine, gamma-glutamylethylamide, is metabolized by renal phosphate-independent glutaminase.
    Biochimica et biophysica acta, 2003, Mar-17, Volume: 1620, Issue:1-3

    Topics: Animals; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Ethylamines; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Glutaminase; Glycylglycine; Isoenzymes; Kidney; Phosphates; Rats; Rats, Wistar; Substrate Specificity

2003
Possible involvement of group I mGluRs in neuroprotective effect of theanine.
    Biochemical and biophysical research communications, 2004, Jul-16, Volume: 320, Issue:1

    Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Isoenzymes; Methoxyhydroxyphenylglycol; Neurons; Neuroprotective Agents; Phospholipase C beta; Phospholipase C gamma; Rats; Receptors, Metabotropic Glutamate; Type C Phospholipases

2004
Theanine, a specific glutamate derivative in green tea, reduces the adverse reactions of doxorubicin by changing the glutathione level.
    Cancer letters, 2004, Aug-30, Volume: 212, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Female; Glutamates; Glutamic Acid; Glutathione; Glutathione Peroxidase; Humans; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Models, Biological; Models, Chemical; Myocardium; Neoplasm Transplantation; Oxidative Stress; Oxygen; Tea; Temperature; Time Factors

2004
Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission.
    Nutritional neuroscience, 2005, Volume: 8, Issue:4

    Topics: Animals; Aspartic Acid; Brain; Dicarboxylic Acids; Dopamine; Glutamates; Glutamic Acid; Glycine; Male; Microdialysis; Neurotransmitter Agents; Neurotransmitter Uptake Inhibitors; Pyrrolidines; Rats; Rats, Wistar

2005
Characterization of theanine-forming enzyme from Methylovorus mays no. 9 in respect to utilization of theanine production.
    Bioscience, biotechnology, and biochemistry, 2007, Volume: 71, Issue:2

    Topics: Adenosine Triphosphate; Ammonium Sulfate; Cations, Divalent; Cell Membrane Permeability; Chromatography, DEAE-Cellulose; Culture Media; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Energy Transfer; Ethylamines; Fermentation; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Indicators and Reagents; Methanobacteriaceae; Reverse Transcriptase Polymerase Chain Reaction

2007
Theogallin and L-theanine as active ingredients in decaffeinated green tea extract: I. electrophysiological characterization in the rat hippocampus in-vitro.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:8

    Topics: Amino Acids; Animals; Electrophysiology; Gallic Acid; Glutamates; Glutamic Acid; Hippocampus; Lethal Dose 50; Male; Memory; Plant Extracts; Plant Leaves; Pyramidal Cells; Quinic Acid; Rats; Rats, Sprague-Dawley; Tea

2007
Enhancement of antigen-specific immunoglobulin G production in mice by co-administration of L-cystine and L-theanine.
    The Journal of veterinary medical science, 2007, Volume: 69, Issue:12

    Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Antibody Specificity; Cystine; Dextrans; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Glutathione; Hemocyanins; Immunoglobulin E; Immunoglobulin G; Interferon-gamma; Interleukin-10; Liver; Mice; Mice, Inbred BALB C

2007
Enzymatic synthesis of theanine from glutamic acid γ-methyl ester and ethylamine by immobilized Escherichia coli cells with γ-glutamyltranspeptidase activity.
    Amino acids, 2010, Volume: 39, Issue:5

    Topics: Biocatalysis; Cells, Immobilized; Escherichia coli; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Methyl Ethers; Molecular Conformation; Substrate Specificity; Temperature

2010
Synthesis of theanine from glutamic acid gamma-methyl ester and ethylamine catalyzed by Escherichia coli having gamma-glutamyltranspeptidase activity.
    Biotechnology letters, 2010, Volume: 32, Issue:8

    Topics: Catalysis; Escherichia coli; Ethylamines; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Methyl Ethers; Substrate Specificity; Temperature

2010
L-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced excitotoxicity via inhibition of the NMDA receptor pathway.
    Neuroscience, 2010, Jul-14, Volume: 168, Issue:3

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Apoptosis; Calcium; Caspase 3; Cell Line, Tumor; Cell Survival; Dizocilpine Maleate; Glutamates; Glutamic Acid; Humans; JNK Mitogen-Activated Protein Kinases; Mutation; Neurons; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peptide Fragments; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Transgenes

2010
L-Theanine intake increases threshold for limbic seizures but decreases threshold for generalized seizures.
    Nutritional neuroscience, 2013, Volume: 16, Issue:2

    Topics: Animals; Disease Models, Animal; GABA Agents; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Male; Mice; Mice, Inbred Strains; Microdialysis; Pentylenetetrazole; Pilocarpine; Seizures; Tea

2013
Stable isotope dilution HILIC-MS/MS method for accurate quantification of glutamic acid, glutamine, pyroglutamic acid, GABA and theanine in mouse brain tissues.
    Biomedical chromatography : BMC, 2016, Volume: 30, Issue:1

    Topics: Animals; Brain; Chromatography, Liquid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Hydrophobic and Hydrophilic Interactions; Male; Mice; Pyrrolidonecarboxylic Acid; Tandem Mass Spectrometry

2016
Acute intravenous administration of dietary constituent theanine suppresses noxious neuronal transmission of trigeminal spinal nucleus caudalis in rats.
    Brain research bulletin, 2017, Volume: 131

    Topics: Action Potentials; Administration, Intravenous; Animals; Electrophysiology; Glutamates; Glutamic Acid; Male; Neurons; Nociceptive Pain; Nociceptors; Physical Stimulation; Rats; Rats, Wistar; Synaptic Transmission; Trigeminal Nucleus, Spinal

2017
Evolving transpeptidase and hydrolytic variants of γ-glutamyl transpeptidase from Bacillus licheniformis by targeted mutations of conserved residue Arg109 and their biotechnological relevance.
    Journal of biotechnology, 2017, May-10, Volume: 249

    Topics: Arginine; Bacillus licheniformis; Bacterial Proteins; Enzyme Stability; Escherichia coli; gamma-Glutamyltransferase; Glutamates; Glutamic Acid; Hydrolysis; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Sodium Chloride

2017
Improvement of Antioxidant Defences and Mood Status by Oral GABA Tea Administration in a Mouse Model of Post-Stroke Depression.
    Nutrients, 2017, Apr-29, Volume: 9, Issue:5

    Topics: Affect; Animals; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Polyphenols; Reproducibility of Results; Stroke; Tea

2017
Characterization of l-Theanine Excitatory Actions on Hippocampal Neurons: Toward the Generation of Novel N-Methyl-d-aspartate Receptor Modulators Based on Its Backbone.
    ACS chemical neuroscience, 2017, 08-16, Volume: 8, Issue:8

    Topics: Animals; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; Mice; Neurons; Oocytes; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Xenopus

2017
Studies on the Biochemical Formation Pathway of the Amino Acid l-Theanine in Tea (Camellia sinensis) and Other Plants.
    Journal of agricultural and food chemistry, 2017, Aug-23, Volume: 65, Issue:33

    Topics: Amide Synthases; Biosynthetic Pathways; Camellia sinensis; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Plant Proteins

2017
Effects of introducing theanine or glutamic acid core to tralopyril on systemicity and insecticidal activity.
    Pesticide biochemistry and physiology, 2017, Volume: 141

    Topics: Animals; Glutamates; Glutamic Acid; Insecticides; Larva; Phloem; Pyrethrins; Pyrroles; Ricinus; Seedlings; Structure-Activity Relationship

2017
Differential accumulation of specialized metabolite l-theanine in green and albino-induced yellow tea (Camellia sinensis) leaves.
    Food chemistry, 2019, Mar-15, Volume: 276

    Topics: Camellia sinensis; Ethylamines; Glutamates; Glutamic Acid; Hydrolases; Plant Leaves

2019
Efficient fermentative production of L-theanine by Corynebacterium glutamicum.
    Applied microbiology and biotechnology, 2020, Volume: 104, Issue:1

    Topics: Adenosine Triphosphate; Carbon-Nitrogen Ligases; Corynebacterium glutamicum; Ethylamines; Fermentation; Glutamates; Glutamic Acid; Industrial Microbiology; Metabolic Engineering

2020
Development of a highly efficient and specific L-theanine synthase.
    Applied microbiology and biotechnology, 2020, Volume: 104, Issue:8

    Topics: Adenosine Triphosphate; Amide Synthases; Catalysis; Directed Molecular Evolution; Escherichia coli; Ethylamines; Glutamate-Cysteine Ligase; Glutamates; Glutamic Acid; High-Throughput Screening Assays; Industrial Microbiology; Protein Engineering

2020
Characterization of l-Theanine Hydrolase
    Journal of agricultural and food chemistry, 2020, Sep-30, Volume: 68, Issue:39

    Topics: Amino Acid Sequence; Camellia sinensis; Ethylamines; Glutamates; Glutamic Acid; Hydrolases; Plant Leaves; Plant Proteins; Protein Transport; Sequence Alignment

2020
Development and Application of a Fast Gas Chromatographic Method Offer New Insights into l-theanine Production Regulation in
    Journal of agricultural and food chemistry, 2021, Sep-22, Volume: 69, Issue:37

    Topics: Camellia sinensis; Glutamates; Glutamic Acid; Plant Leaves; Plant Proteins; Tea

2021
Stable Isotope-Labeled Precursor Tracing Reveals that l-Alanine is Converted to l-Theanine
    Journal of agricultural and food chemistry, 2021, Dec-22, Volume: 69, Issue:50

    Topics: Alanine; Camellia sinensis; Ethylamines; Glutamates; Glutamic Acid; Isotopes; Plant Leaves; Tea

2021
Characterization of
    Journal of agricultural and food chemistry, 2022, Jan-26, Volume: 70, Issue:3

    Topics: Camellia sinensis; Glutamates; Glutamic Acid; Plant Leaves; Plant Proteins; Tea

2022
Potential role of green tea amino acid l-theanine in the activation of innate immune response by enhancing expression of cytochrome b
    Microbiology and immunology, 2022, Volume: 66, Issue:6

    Topics: Amino Acids; Cytochromes b; Glutamates; Glutamic Acid; Glutamine; Humans; Immunity, Innate; Leukocytes; NADPH Oxidases; Neutrophils; Phosphoproteins; Reactive Oxygen Species; Superoxides; Tea; Tretinoin

2022
L-theanine attenuates LPS-induced motor deficit in experimental rat model of Parkinson's disease: emphasis on mitochondrial activity, neuroinflammation, and neurotransmitters.
    Psychopharmacology, 2023, Volume: 240, Issue:7

    Topics: Animals; Disease Models, Animal; Glutamic Acid; Lipopolysaccharides; Mitochondria; Neuroinflammatory Diseases; Neuroprotective Agents; Neurotransmitter Agents; Parkinson Disease; Rats

2023