glutamic acid and propofol

glutamic acid has been researched along with propofol in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (18.46)18.2507
2000's27 (41.54)29.6817
2010's22 (33.85)24.3611
2020's4 (6.15)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Battistin, T; Bianchi, M; Galzigna, L1
Albert, A; Bonhomme, V; Collette, J; Hans, P; Moonen, G1
Lambert, DG; Nicol, B; Rowbotham, DJ2
Bullock, R; Rafferty, C; Stewart, L; Teasdale, GM1
Bickler, PE; Buck, LT; Feiner, JR1
Hemmings, HC; Ratnakumari, L1
Cottrell, JE; Kass, IS; Zhu, H1
Kitamura, R; Miyawaki, I; Mori, K; Nakamura, K; Yokubol, B1
Bonicalzi, V; Canavero, S1
Cechetto, DF; Gelb, A; Hanifi-Moghaddam, P; Sitar, SM; Siushansian, R; Wilson, JX1
Carlo, D; Chang, J; Gillenwater, G; Hendler, S; Khoh-Reiter, S; Sagara, Y; Schubert, D1
Buggy, DJ; Lambert, DG; Nicol, B; Rowbotham, DJ1
Nakayama, R; Ushijima, K; Yano, T1
Gelb, AW; Korcok, J; Peters, CE; Wilson, JX1
Blackbeer, J; Giunta, AL; Harrison, NL; Hemmings, HC; Jenkins, A; Krasowski, MD; Lingamaneni, R; MacIver, MB; Truong, T1
Jevtovic-Todorovic, V; Olney, JW; Powell, S; Wozniak, DF1
Daskalopoulos, R; Farhangkhgoee, P; Gelb, AW; Karmazyn, M; Korcok, J; Wilson, JX1
Birch, ML; Hemmings, HC; Lingamaneni, R1
Do, SH; Ham, BM; Zuo, Z1
Bruder, NJ; Gouin, FM; Guillet, BA; Masmejean, FM; Nieoullon, AL; Pisano, PM; Velly, LJ1
Chen, HZ; Wang, ZJ; Xia, M; Xue, QS; Yu, BW1
Blobner, M; Engelhard, K; Hoffman, WE; Kochs, E; Matthes, B; Werner, C1
Kiddoo, CE; Lukatch, HS; Maciver, MB1
Goiny, M; Grasshoff, C; Herrera-Marschitz, M; Kretschmer, BD1
Bufler, J; Cordes, AL; Krampfl, K; Schlesinger, F; Wolfes, H1
Kempski, OS; Stover, JF1
Abbas, SY; Goldstein, PA; Harrison, NL; Ying, SW1
Cao, J; Liu, H; Shang, Y; Yao, S; Zeng, Y1
Arora, A; Fibuch, EE; Kozinn, J; Mao, L; Wang, JQ; Yang, L1
Allritz, C; Engele, J; Figiel, M; Lehmann, C1
Aoe, H; Kobayashi, M; Morita, K; Takata, K; Takeda, Y; Taninishi, H1
Galdi, S; Hemmings, HC; Hendrick, JP; Snyder, GL1
Delphin, E; Li, KY; Xiao, C; Xiong, M; Ye, JH1
Hang, YN; Jing, W; Wang, L1
Chiang, HS; Lin, TY; Lu, CW; Wang, SJ1
Gao, W; Ge, Y; Wang, W; Wu, S; Xu, L; Zhang, H; Zhang, J1
Chai, CY; Wu, WC; Yang, CY1
Cao, J; Dong, J; Li, P; Li, Y; Min, S; Wei, K1
Shang, Y1
Cai, J; Hu, Y; Li, L; Li, Q; Li, S; Li, W; Zhang, M1
Andrada, J; Jinks, SL1
Bleichner, JP; Laviolle, B; Malledant, Y; Morandi, X; Seguin, P; Tanguy, M1
Dong, J; Li, P; Liu, C; Liu, D; Liu, XB; Luo, J; Min, S; Wei, K1
Fu, JQ; Huang, DD; Wang, DF; Zhou, XF1
Davies, PA; Deeb, TZ; Frost, GD; Moss, SJ; Nakamura, Y1
Akaike, N; Kotani, N; Nonaka, K; Shin, MC; Wakita, M1
Liu, C; Liu, D; Min, S; Zhang, XN1
Hao, X; Luo, J; Min, S; Xie, F; Zhang, F; Zhu, X1
Ding, HZ; Jiang, S; Tang, QF; Zeng, YM; Zhang, DX1
Liu, C; Liu, G; Zhang, XN1
Akaike, N; Kotani, N; Shoudai, K; Wakita, M; Yamaga, T1
Liu, C; Liu, WF1
Fu, S; Jin, J; Li, W; Wei, Y; Yang, W; Yao, J; Yue, Z; Zhang, L1
Wang, BA; Wang, MY; Zhang, HH; Zheng, C1
Bao, M; Guan, Y; Li, X; Shi, R; Wang, Y; Xie, F; Yue, Y1
Chen, YM; Gao, YT; Guo, D; Li, T; Li, YL; Wang, GL; Wang, HY; Wang, XY; Yang, CY; Yang, Z; Zhu, M1
Dong, HL; Franks, NP; Gelegen, C; Harding, EC; Hawkins, ED; Houston, CM; Miracca, G; Ran, MZ; Tossell, K; Vyssotski, AL; Wisden, W; Ye, Z; Yu, X; Yustos, R1
Duan, Z; Fu, B; Li, J; Shi, F; Yu, T; Zhang, Y1
Baik, HJ; Moon, S1
Jiang, Q; Li, A; Xin, W; Yu, S1
Chen, L; Chen, Y; Cui, J; Li, Y; Qin, W; Zhu, D1
Feng, Y; Liu, J; Zhang, WS1
Chang, P; Feng, Y; Kang, Y; Li, CY; Liao, P; Liu, J; Zhang, WS1

Reviews

1 review(s) available for glutamic acid and propofol

ArticleYear
The neurochemistry of central pain: evidence from clinical studies, hypothesis and therapeutic implications.
    Pain, 1998, Volume: 74, Issue:2-3

    Topics: Anesthetics, Intravenous; Baclofen; Cerebral Cortex; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Midazolam; Middle Aged; Pain; Propofol; Thalamus

1998

Trials

3 trial(s) available for glutamic acid and propofol

ArticleYear
Continuous monitoring of jugular bulb oxygen saturation and the effect of drugs acting on cerebral metabolism.
    Acta neurochirurgica. Supplementum, 1993, Volume: 59

    Topics: Adolescent; Adult; Aged; Brain; Brain Injuries; Child; Child, Preschool; Dose-Response Relationship, Drug; Energy Metabolism; Excitatory Amino Acid Antagonists; Female; Follow-Up Studies; Glutamic Acid; Hemodynamics; Humans; Infusions, Intravenous; Intracranial Pressure; Male; Middle Aged; Monitoring, Physiologic; Neurologic Examination; Oximetry; Oxygen Consumption; Propofol

1993
Anesthesia increases circulating glutamate in neurosurgical patients.
    Acta neurochirurgica, 2005, Volume: 147, Issue:8

    Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Craniotomy; Diskectomy; Female; Glutamic Acid; Humans; Isoflurane; Male; Middle Aged; Propofol; Prospective Studies

2005
Cerebral microdialysis effects of propofol versus midazolam in severe traumatic brain injury.
    Journal of neurotrauma, 2012, Apr-10, Volume: 29, Issue:6

    Topics: Adult; Biomarkers; Brain Chemistry; Brain Injuries; Cerebral Cortex; Female; Glucose; Glutamic Acid; Glycerol; Humans; Hypnotics and Sedatives; Lactic Acid; Male; Microdialysis; Midazolam; Neuroprotective Agents; Propofol; Pyruvic Acid; Single-Blind Method

2012

Other Studies

61 other study(ies) available for glutamic acid and propofol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
2,6-diisopropylphenol, a general anesthetic, inhibits glutamate action on rat synaptosomes.
    Neurochemical research, 1991, Volume: 16, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Brain; Calcium; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kinetics; Male; Ouabain; Propofol; Rats; Rats, Inbred Strains; Synaptosomes

1991
Propofol protects cultured rat hippocampal neurons against N-methyl-D-aspartate receptor-mediated glutamate toxicity.
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Phosphopyruvate Hydratase; Propofol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Time Factors

1994
Glutamate uptake is not a major target site for anaesthetic agents.
    British journal of anaesthesia, 1995, Volume: 75, Issue:1

    Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Animals; Brain; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glutamic Acid; Kinetics; Morphine; Propofol; Rats; Rats, Wistar; Synaptosomes; Thiopental

1995
Comparison of the uptake of [3H]glutamate into rat cerebrocortical and cerebellar synaptosomes. Effects of anaesthetic agents.
    Biochemical Society transactions, 1994, Volume: 22, Issue:4

    Topics: Anesthetics; Animals; Biological Transport; Cerebellum; Cerebral Cortex; Female; Glutamic Acid; Ketamine; Kinetics; Propofol; Rats; Synaptosomes; Thiopental; Tritium

1994
Volatile and intravenous anesthetics decrease glutamate release from cortical brain slices during anoxia.
    Anesthesiology, 1995, Volume: 83, Issue:6

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cerebral Cortex; Enflurane; Glutamic Acid; Halothane; Hypoxia; In Vitro Techniques; Propofol; Rats; Rats, Sprague-Dawley; Thiopental

1995
Effects of propofol on sodium channel-dependent sodium influx and glutamate release in rat cerebrocortical synaptosomes.
    Anesthesiology, 1997, Volume: 86, Issue:2

    Topics: 4-Aminopyridine; Anesthetics, Intravenous; Animals; Calcium Channels; Cerebral Cortex; Glutamic Acid; Male; Potassium Chloride; Propofol; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Synaptosomes; Veratridine

1997
The effect of thiopental and propofol on NMDA- and AMPA-mediated glutamate excitotoxicity.
    Anesthesiology, 1997, Volume: 87, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthetics, Intravenous; Animals; Dimethyl Sulfoxide; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Propofol; Rats; Rats, Sprague-Dawley; Thiopental

1997
Suppression of cyclic guanosine monophosphate formation in rat cerebellar slices by propofol, ketamine and midazolam.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:12

    Topics: Anesthetics, Intravenous; Animals; Cerebellum; Cyclic GMP; Depression, Chemical; Glutamic Acid; In Vitro Techniques; Ketamine; Midazolam; N-Methylaspartate; Nitroprusside; Propofol; Rats; Rats, Wistar; Vasodilator Agents

1997
Propofol prevents peroxide-induced inhibition of glutamate transport in cultured astrocytes.
    Anesthesiology, 1999, Volume: 90, Issue:5

    Topics: Anesthetics, Intravenous; Animals; Astrocytes; Biological Transport; Cells, Cultured; Glutamic Acid; Lipid Peroxidation; Mitochondria; Neuroprotective Agents; Propofol; Rats; Rats, Wistar; tert-Butylhydroperoxide

1999
Propofol hemisuccinate protects neuronal cells from oxidative injury.
    Journal of neurochemistry, 1999, Volume: 73, Issue:6

    Topics: Animals; Apoptosis; Buthionine Sulfoximine; Glutamic Acid; Hippocampus; Homocysteine; Hydrogen Peroxide; Methylprednisolone; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Propofol; Rats; Reactive Oxygen Species; Tocopherols; Vitamin E

1999
Effects of intravenous anesthetic agents on glutamate release: a role for GABAA receptor-mediated inhibition.
    Anesthesiology, 2000, Volume: 92, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Bicuculline; Cerebral Cortex; Female; GABA Antagonists; GABA-A Receptor Antagonists; Glutamic Acid; In Vitro Techniques; Ketamine; Neurons; Potassium; Propofol; Rats; Rats, Wistar; Receptors, GABA-A; Thiopental

2000
Intracerebroventricular propofol is neuroprotective against transient global ischemia in rats: extracellular glutamate level is not a major determinant.
    Brain research, 2000, Nov-10, Volume: 883, Issue:1

    Topics: Animals; Cell Count; Extracellular Space; Glutamic Acid; Hippocampus; Injections, Intraventricular; Ischemic Attack, Transient; Male; Neuroprotective Agents; Propofol; Pyramidal Cells; Rats; Rats, Wistar

2000
Anesthetic concentrations of propofol protect against oxidative stress in primary astrocyte cultures: comparison with hypothermia.
    Anesthesiology, 2001, Volume: 94, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Astrocytes; Glutamic Acid; Hypothermia, Induced; Oxidative Stress; Propofol; Rats; Rats, Wistar

2001
Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia.
    Anesthesiology, 2001, Volume: 94, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Behavior, Animal; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Humans; Hypnotics and Sedatives; In Vitro Techniques; Male; Mice; Neurotransmitter Agents; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Synaptosomes; Xenopus laevis

2001
Propofol and sodium thiopental protect against MK-801-induced neuronal necrosis in the posterior cingulate/retrosplenial cortex.
    Brain research, 2001, Sep-21, Volume: 913, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; Necrosis; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Thiopental

2001
Propofol protection of sodium-hydrogen exchange activity sustains glutamate uptake during oxidative stress.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:5

    Topics: Amiloride; Anesthetics, Intravenous; Animals; Astrocytes; Bicarbonates; Cells, Cultured; Free Radical Scavengers; Glutamic Acid; Glutathione; Hydrogen-Ion Concentration; Microscopy, Fluorescence; Neuroprotective Agents; Oxidative Stress; Propofol; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; tert-Butylhydroperoxide; Tritium; Vitamin E

2001
Widespread inhibition of sodium channel-dependent glutamate release from isolated nerve terminals by isoflurane and propofol.
    Anesthesiology, 2001, Volume: 95, Issue:6

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cerebral Cortex; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Isoflurane; Mice; Neostriatum; Nerve Endings; Propofol; Rats; Receptors, GABA-A; Sodium Channel Blockers; Sodium Channels; Species Specificity; Synaptosomes

2001
Effects of propofol on the activity of rat glutamate transporter type 3 expressed in Xenopus oocytes: the role of protein kinase C.
    Neuroscience letters, 2003, Jun-05, Volume: 343, Issue:2

    Topics: Amino Acid Transport System X-AG; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Extracellular Space; Gene Expression; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Membrane Potentials; Oocytes; Propofol; Protein Kinase C; Rats; Symporters; Tetradecanoylphorbol Acetate; Xenopus

2003
Neuroprotective effects of propofol in a model of ischemic cortical cell cultures: role of glutamate and its transporters.
    Anesthesiology, 2003, Volume: 99, Issue:2

    Topics: Amino Acid Transport System X-AG; Amino Acids; Anesthetics, Intravenous; Animals; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Gangliosides; Glucose; Glutamic Acid; Immunohistochemistry; L-Lactate Dehydrogenase; Microscopy, Phase-Contrast; Neurons; Neuroprotective Agents; Oxygen; Pregnancy; Propofol; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles

2003
[The influences of propofol on different kinds of brain injuries in rat brain slices].
    Zhonghua yi xue za zhi, 2003, Jul-10, Volume: 83, Issue:13

    Topics: Animals; Brain; Brain Injuries; Cerebral Cortex; Dose-Response Relationship, Drug; Free Radical Scavengers; Glucose; Glutamic Acid; Hippocampus; Hydrogen Peroxide; Hypoxia, Brain; In Vitro Techniques; Male; Neuroprotective Agents; Propofol; Rats; Rats, Sprague-Dawley; Time Factors

2003
The effect of sevoflurane and propofol on cerebral neurotransmitter concentrations during cerebral ischemia in rats.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:4

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Ischemia; Catecholamines; Chromatography, High Pressure Liquid; Electroencephalography; Epinephrine; Glutamic Acid; Hypotension; Male; Methyl Ethers; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Propofol; Rats; Rats, Sprague-Dawley; Reperfusion; Sevoflurane

2003
Anesthetic-induced burst suppression EEG activity requires glutamate-mediated excitatory synaptic transmission.
    Cerebral cortex (New York, N.Y. : 1991), 2005, Volume: 15, Issue:9

    Topics: Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bicuculline; Carbachol; Electroencephalography; Electrophysiology; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Isoflurane; Kinetics; Male; Patch-Clamp Techniques; Propofol; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synaptic Transmission; Thiopental

2005
Modulation of ventral pallidal dopamine and glutamate release by the intravenous anesthetic propofol studied by in vivo microdialysis.
    Amino acids, 2005, Volume: 28, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Behavior, Animal; Bicuculline; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Dopamine; GABA Antagonists; Glutamic Acid; Hallucinations; Male; Neurons; Propofol; Rats; Rats, Sprague-Dawley; Sexual Dysfunctions, Psychological; Telencephalon

2005
Effects of propofol on recombinant AMPA receptor channels.
    European journal of pharmacology, 2005, Mar-21, Volume: 511, Issue:1

    Topics: Cell Line; DNA, Recombinant; Glutamic Acid; Humans; Membrane Potentials; Propofol; Receptors, AMPA; Transfection

2005
Propofol block of I(h) contributes to the suppression of neuronal excitability and rhythmic burst firing in thalamocortical neurons.
    The European journal of neuroscience, 2006, Volume: 23, Issue:2

    Topics: Action Potentials; Analysis of Variance; Animals; Bicuculline; Cell Count; Cyclic AMP; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Free Radical Scavengers; GABA Antagonists; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Immunohistochemistry; In Vitro Techniques; Ion Channels; Membrane Potentials; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periodicity; Potassium Channels; Propofol; Pyrimidines; Thalamus; Transfection

2006
Effect of propofol on glutamate and gamma-aminobutyric acid release from rat hippocampal synaptosomes.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Calcium; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Propofol; Rats; Rats, Sprague-Dawley; Synaptosomes

2005
Inhibition of glutamatergic activation of extracellular signal-regulated protein kinases in hippocampal neurons by the intravenous anesthetic propofol.
    Anesthesiology, 2006, Volume: 105, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Blotting, Western; Calcium; Cell Survival; Cells, Cultured; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Neurons; Phosphorylation; Pregnancy; Propofol; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Transmission

2006
Gap junctional control of glial glutamate transporter expression.
    Molecular and cellular neurosciences, 2007, Volume: 35, Issue:1

    Topics: Animals; Anticonvulsants; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Connexin 43; Excitatory Amino Acid Transporter 2; Female; Gap Junctions; Glutamic Acid; Liver Neoplasms; Luciferases; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligodendroglia; Pregnancy; Propofol; Rats; Rats, Sprague-Dawley; RNA Interference; Stem Cells

2007
Quantitative evaluation of the neuroprotective effects of thiopental sodium, propofol, and halothane on brain ischemia in the gerbil: effects of the anesthetics on ischemic depolarization and extracellular glutamate concentration.
    Journal of neurosurgical anesthesiology, 2007, Volume: 19, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Brain Ischemia; Electroencephalography; Extracellular Space; Gerbillinae; Glutamic Acid; Halothane; Male; Microdialysis; Neurons; Neuroprotective Agents; Propofol; Thiopental; Time Factors

2007
General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo.
    Neuropharmacology, 2007, Volume: 53, Issue:5

    Topics: Anesthetics, Dissociative; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Blotting, Western; Cerebral Cortex; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Isoflurane; Ketamine; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Nerve Tissue Proteins; Neuroprotective Agents; Phosphorylation; Propofol; Receptors, Glutamate; Signal Transduction; Tyrosine 3-Monooxygenase

2007
Nanomolar propofol stimulates glutamate transmission to dopamine neurons: a possible mechanism of abuse potential?
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:1

    Topics: Animals; Dopamine; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Neurons; Presynaptic Terminals; Propofol; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Substance-Related Disorders; Synaptic Transmission; Ventral Tegmental Area

2008
Glutamate-induced c-Jun expression in neuronal PC12 cells: the effects of ketamine and propofol.
    Journal of neurosurgical anesthesiology, 2008, Volume: 20, Issue:2

    Topics: Analgesics; Anesthetics, Intravenous; Animals; Blotting, Western; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression; Glutamic Acid; In Situ Nick-End Labeling; Ketamine; Neurons; Neuroprotective Agents; PC12 Cells; Propofol; Proto-Oncogene Proteins c-jun; Rats

2008
Facilitation of glutamate release from rat cerebral cortex nerve terminal by subanesthetic concentration propofol.
    Synapse (New York, N.Y.), 2009, Volume: 63, Issue:9

    Topics: 4-Aminopyridine; Anesthetics, Intravenous; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Glutamic Acid; Male; Membrane Potentials; Potassium Channel Blockers; Presynaptic Terminals; Propofol; Protein Kinase C; Rats; Rats, Sprague-Dawley; Seizures; Signal Transduction; Synaptic Transmission; Synaptosomes; Vesicular Glutamate Transport Proteins

2009
Effect of propofol on the levels of neurotransmitters in normal human brain: a magnetic resonance spectroscopy study.
    Neuroscience letters, 2009, Dec-31, Volume: 467, Issue:3

    Topics: Acetylcholine; Adult; Anesthetics, Intravenous; Aspartic Acid; Brain; Brain Chemistry; Choline; Consciousness; Creatine; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance Spectroscopy; Male; Neural Inhibition; Neurotransmitter Agents; Propofol; Young Adult

2009
Modulation of propofol on the effects of blood pressure and firing activity of related neurons in the medulla.
    The Chinese journal of physiology, 2009, Nov-30, Volume: 52, Issue:5 Suppl

    Topics: Animals; Bicuculline; Blood Pressure; Cats; Female; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Medulla Oblongata; Neurons; Propofol

2009
Effects of electroconvulsive therapy and propofol on spatial memory and glutamatergic system in hippocampus of depressed rats.
    The journal of ECT, 2010, Volume: 26, Issue:2

    Topics: Animals; Combined Modality Therapy; Depression; Disease Models, Animal; Electroconvulsive Therapy; Glutamic Acid; Hippocampus; Hypnotics and Sedatives; Male; Memory; Propofol; Rats; Rats, Sprague-Dawley; Reference Standards

2010
[Effect of propofol on glutamate, ascorbic acid release in hippocampus during global cerebral ischemia/reperfusion in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2006, Volume: 22, Issue:1

    Topics: Animals; Ascorbic Acid; Brain Ischemia; Glutamic Acid; Hippocampus; Male; Propofol; Rats; Rats, Wistar; Reperfusion Injury

2006
The neuroprotective effect of propofol against brain ischemia mediated by the glutamatergic signaling pathway in rats.
    Neurochemical research, 2011, Volume: 36, Issue:10

    Topics: Anesthetics, Intravenous; Animals; Brain Ischemia; Glutamic Acid; Male; Neurons; Neuroprotective Agents; Propofol; Random Allocation; Rats; Rats, Wistar; Signal Transduction

2011
Validation and insights of anesthetic action in an early vertebrate network: the isolated lamprey spinal cord.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:5

    Topics: Algorithms; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Electric Stimulation; GABA-A Receptor Antagonists; Glutamic Acid; In Vitro Techniques; Isoflurane; Lampreys; Locomotion; Motor Activity; Nerve Net; Physical Stimulation; Picrotoxin; Propofol; Spinal Cord; Spinal Nerve Roots; Strychnine; Swimming

2011
Effects of propofol and dizocilpine maleate on the cognitive abilities and the hyperphosphorylation of Tau protein of rats after the electroconvulsive therapy.
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2012, Volume: 34, Issue:4

    Topics: Animals; Depression; Disease Models, Animal; Dizocilpine Maleate; Electroconvulsive Therapy; Glutamic Acid; Hippocampus; Male; Maze Learning; Memory; Phosphorylation; Propofol; Rats; Rats, Sprague-Dawley; tau Proteins

2012
[The protective effect of propofol pretreatment on glutamate injury of neonatal rat brain slices].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2012, Volume: 24, Issue:12

    Topics: Animals; Brain; Glutamic Acid; L-Lactate Dehydrogenase; Neurons; Propofol; Rats; Rats, Sprague-Dawley; Tissue Culture Techniques

2012
Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states.
    The European journal of neuroscience, 2013, Volume: 38, Issue:3

    Topics: Animals; Cells, Cultured; Chlorides; Diazepam; Furosemide; GABA Modulators; Glutamic Acid; Homeostasis; K Cl- Cotransporters; Muscimol; Neural Inhibition; Propofol; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sodium Potassium Chloride Symporter Inhibitors; Symporters

2013
Effects of propofol on GABAergic and glutamatergic transmission in isolated hippocampal single nerve-synapse preparations.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Animals; Calcium; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neurons; Propofol; Rats; Rats, Wistar; Sodium; Synapses; Synaptic Transmission; Time Factors

2013
Effects of propofol, ginsenoside Rg-1, protein phosphatase-2a, and lithium on the learning and memory in rats and the content of glutamic acid in hippocampus after the electroconvulsive therapy.
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2014, Volume: 36, Issue:3

    Topics: Animals; Electroshock; Ginsenosides; Glutamic Acid; Hippocampus; Lithium; Male; Maze Learning; Memory; Propofol; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley

2014
Propofol inhibits inflammatory cytokine-mediated glutamate uptake dysfunction to alleviate learning/memory impairment in depressed rats undergoing electroconvulsive shock.
    Brain research, 2015, Jan-21, Volume: 1595

    Topics: Analysis of Variance; Animals; Cytokines; Depression; Disease Models, Animal; Food Deprivation; Food Preferences; Gene Expression Regulation; Glutamic Acid; Hypnotics and Sedatives; Learning Disabilities; Male; Maze Learning; Propofol; Rats; Rats, Sprague-Dawley; Water Deprivation

2015
An in vitro study of the neuroprotective effect of propofol on hypoxic hippocampal slice.
    Brain injury, 2014, Volume: 28, Issue:13-14

    Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Neuroprotective Agents; Propofol; Rats; Rats, Sprague-Dawley

2014
Comparison of the neuropsychological mechanisms of 2,6-diisopropylphenol and N-methyl-D-aspartate receptor antagonist against electroconvulsive therapy-induced learning and memory impairment in depressed rats.
    Molecular medicine reports, 2015, Volume: 12, Issue:3

    Topics: Animals; Depressive Disorder; Dizocilpine Maleate; Electroconvulsive Therapy; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Learning Disabilities; Male; Maze Learning; Memory Disorders; Propofol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2015
Modulation of inhibitory and excitatory fast neurotransmission in the rat CNS by heavy water (D2O).
    Journal of neurophysiology, 2015, Volume: 114, Issue:2

    Topics: Animals; CA3 Region, Hippocampal; Central Nervous System Agents; Deuterium Oxide; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Inhibitory Postsynaptic Potentials; Neurons; Nitrous Oxide; Presynaptic Terminals; Propofol; Rats, Wistar; Receptors, GABA-A; Tissue Culture Techniques

2015
Propofol can Protect Against the Impairment of Learning-memory Induced by Electroconvulsive Shock via Tau Protein Hyperphosphorylation in Depressed Rats.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2015, Volume: 30, Issue:2

    Topics: Animals; Depression; Dizocilpine Maleate; Electroshock; Glutamic Acid; Learning Disabilities; Male; Memory Disorders; Phosphorylation; Propofol; Rats; Rats, Sprague-Dawley; tau Proteins

2015
Effects of Propofol on Excitatory and Inhibitory Amino Acid Neurotransmitter Balance in Rats with Neurogenic Pulmonary Edema Induced by Subarachnoid Hemorrhage.
    Neurocritical care, 2016, Volume: 24, Issue:3

    Topics: Animals; Brain; Brain Edema; Disease Models, Animal; Excitatory Amino Acids; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neuroprotective Agents; Neurotransmitter Agents; Propofol; Pulmonary Edema; Rats; Rats, Wistar; Subarachnoid Hemorrhage

2016
Inhibitory effects of propofol on excitatory synaptic transmission in supraoptic nucleus neurons in vitro.
    Sheng li xue bao : [Acta physiologica Sinica], 2015, Dec-25, Volume: 67, Issue:6

    Topics: Anesthetics, Intravenous; Animals; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Glutamic Acid; In Vitro Techniques; Neurons; Propofol; Rats; Receptors, Glutamate; Supraoptic Nucleus

2015
Anesthetic propofol normalized the increased release of glutamate and γ-amino butyric acid in hippocampus after paradoxical sleep deprivation in rats.
    Neurological research, 2015, Volume: 37, Issue:12

    Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Hypnotics and Sedatives; Male; Microdialysis; Propofol; Rats; Rats, Sprague-Dawley; Sleep Deprivation; Time Factors

2015
Propofol inhibits invasion and proliferation of C6 glioma cells by regulating the Ca
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 44

    Topics: Anesthetics, Intravenous; Animals; Antineoplastic Agents; Calcium; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Glioma; Glutamic Acid; Glutathione; Propofol; Rats; Receptors, AMPA

2017
Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation.
    Current biology : CB, 2018, 02-19, Volume: 28, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Glutamic Acid; Habenula; HEK293 Cells; Humans; Hypnotics and Sedatives; Male; Mice; Neural Pathways; Propofol

2018
Involvement of Ventral Periaqueductal Gray Dopaminergic Neurons in Propofol Anesthesia.
    Neurochemical research, 2018, Volume: 43, Issue:4

    Topics: Anesthetics, Intravenous; Animals; Dopaminergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Male; Periaqueductal Gray; Propofol; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, GABA-B

2018
Aminophylline and Ephedrine, but Not Flumazenil, Inhibit the Activity of the Excitatory Amino Acid Transporter 3 Expressed in
    BioMed research international, 2018, Volume: 2018

    Topics: Aminophylline; Animals; Ephedrine; Excitatory Amino Acid Transporter 3; Flumazenil; Gene Expression Regulation, Developmental; Glutamic Acid; Oocytes; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Propofol; Protein Kinase C; Protein Kinase Inhibitors; Xenopus laevis

2018
Propofol exerts neuroprotective functions by down-regulating microRNA-19a in glutamic acid-induced PC12 cells.
    BioFactors (Oxford, England), 2020, Volume: 46, Issue:6

    Topics: Animals; Cell Survival; Cells, Cultured; Down-Regulation; Glutamic Acid; Hypnotics and Sedatives; MicroRNAs; Neuroprotection; PC12 Cells; Propofol; Rats

2020
Propofol downregulates the activity of glutamatergic neurons in the basal forebrain via affecting intrinsic membrane properties and postsynaptic GABAARs.
    Neuroreport, 2020, 12-09, Volume: 31, Issue:17

    Topics: Animals; Basal Forebrain; Down-Regulation; Excitatory Postsynaptic Potentials; Glutamic Acid; Hypnotics and Sedatives; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Propofol; Receptors, GABA-A

2020
Etomidate-induced myoclonus correlates with the dysfunction of astrocytes and glutamate transporters in the neocortex of Sprague-Dawley rats.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:17

    Topics: Amino Acid Transport System X-AG; Animals; Anticonvulsants; Astrocytes; Etomidate; Glutamic Acid; Hypnotics and Sedatives; Lidocaine; Male; Myoclonus; Neocortex; Propofol; Rats; Rats, Sprague-Dawley

2022
Etomidate-Induced Myoclonus in Sprague-Dawley Rats Involves Neocortical Glutamate Accumulation and N -Methyl- d -Aspartate Receptor Activity.
    Anesthesia and analgesia, 2023, 07-01, Volume: 137, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Etomidate; Glutamic Acid; Lidocaine; Male; Myoclonus; Neocortex; Propofol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2023