glutamic acid and phenobarbital sodium

glutamic acid has been researched along with phenobarbital sodium in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's7 (50.00)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barinka, C; Hlouchová, K; Konvalinka, J; Lubkowski, J; Majer, P; Mlcochová, P; Plechanovová, A; Rovenská, M; Slusher, BS; Tsukamoto, T1
Bhardwaj, A; Britton, P; Harukuni, I; Hurn, PD; Jackson, PF; Lu, XC; Potter, BM; Robinson, MB; Slusher, BS; Thomas, AG; Tortella, FC; Traystman, RJ; Vornov, JJ; Wozniak, KM; Yudkoff, M1
Jackson, P; Lu, M; Slusher, B; Tsukamoto, T; Vornov, JJ; Wang, E; Wozniak, K1
Dave, JR; Lin, Y; Slusher, BS; Tortella, FC; Ved, H1
Gafurov, B; Grossfeld, RM; Lieberman, EM; Urazaev, AK1
Chen, SR; Pan, HL; Slusher, BS; Wozniak, KM1
Bilak, MM; Coccia, CF; Corse, AM; Rothstein, JD; Slusher, BS; Thomas, AG1
Long, JB; Meyerhoff, JL; Robinson, MB; Slusher, BS; Yourick, DL1
Calvin, D; Rojas, C; Slusher, BS; Thomas, AG; Tsukamoto, T; Vornov, J; Wozniak, KM; Wu, Y1
Ashby, CR; Chun, L; Gardner, EL; Li, J; Li, X; Peng, XQ; Slusher, BS; Thomas, AG; Xi, ZX1
Raffa, RB; Rawls, SM; Song, K; Tallarida, C1
Cheong, YH; Jo, SA; Kim, H; Kim, MJ; Lee, SK; Park, SI; Youn, HS1
Ahn, G; Bing, SJ; Cho, IH; Cho, J; Ha, D; Herath, KH; Jee, Y; Jo, SA; Kim, A; Kim, J; Yu, HS1
Ishimura, T; Moffett, JR; Neale, JH; Nonaka, T; Yamada, T; Yamamoto, T; Zuo, D1

Reviews

1 review(s) available for glutamic acid and phenobarbital sodium

ArticleYear
Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy.
    Advances in experimental medicine and biology, 2006, Volume: 576

    Topics: Analgesics; Animals; Aspartic Acid; Dipeptides; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Molecular Structure; Neurons; Neuroprotective Agents; Organophosphorus Compounds

2006

Other Studies

13 other study(ies) available for glutamic acid and phenobarbital sodium

ArticleYear
Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II.
    Journal of medicinal chemistry, 2007, Jul-12, Volume: 50, Issue:14

    Topics: Crystallography, X-Ray; Glutamate Carboxypeptidase II; Humans; Models, Molecular; Molecular Mimicry; Protein Conformation; Recombinant Proteins

2007
Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury.
    Nature medicine, 1999, Volume: 5, Issue:12

    Topics: Animals; Brain Ischemia; Carboxypeptidases; Culture Techniques; Dipeptides; Disease Models, Animal; Drug Tolerance; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Glutamic Acid; Ischemic Attack, Transient; Mice; Mice, Inbred ICR; Neuroprotective Agents; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Stroke

1999
Blockade of NAALADase: a novel neuroprotective strategy based on limiting glutamate and elevating NAAG.
    Annals of the New York Academy of Sciences, 1999, Volume: 890

    Topics: Animals; Carboxypeptidases; Dipeptides; Glutamate Carboxypeptidase II; Glutamic Acid; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Organophosphorus Compounds; Rats; Reperfusion Injury

1999
Neuroprotection produced by the NAALADase inhibitor 2-PMPA in rat cerebellar neurons.
    European journal of pharmacology, 2000, Aug-18, Volume: 402, Issue:1-2

    Topics: Animals; Carboxypeptidases; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebellum; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamate Carboxypeptidase II; Glutamic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Veratridine

2000
N-acetylaspartylglutamate (NAAG) is the probable mediator of axon-to-glia signaling in the crayfish medial giant nerve fiber.
    Neuroscience, 2001, Volume: 106, Issue:1

    Topics: Animals; Aspartic Acid; Astacoidea; Axons; Carboxypeptidases; Cell Communication; Cysteic Acid; Dipeptides; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamate Carboxypeptidase II; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Nervous System; Neuroglia; Organophosphorus Compounds; Receptors, Glutamate; Signal Transduction; Time Factors

2001
Effect of 2-(phosphono-methyl)-pentanedioic acid on allodynia and afferent ectopic discharges in a rat model of neuropathic pain.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:2

    Topics: Animals; Behavior, Animal; Carboxypeptidases; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Glutamic Acid; Injections, Intravenous; Male; Neurons, Afferent; Neuroprotective Agents; Organophosphorus Compounds; Pain; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy

2002
NAALADase inhibition protects motor neurons against chronic glutamate toxicity.
    European journal of pharmacology, 2003, Jun-27, Volume: 471, Issue:3

    Topics: Animals; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Glutamic Acid; Motor Neurons; Neuroprotective Agents; Organ Culture Techniques; Organophosphorus Compounds; Rats

2003
Inhibition of glutamate carboxypeptidase II (NAALADase) protects against dynorphin A-induced ischemic spinal cord injury in rats.
    European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3

    Topics: Animals; Anterior Horn Cells; Cell Count; Dose-Response Relationship, Drug; Dynorphins; Glutamate Carboxypeptidase II; Glutamic Acid; Ischemia; Male; Motor Activity; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Spinal Cord; Time Factors

2005
Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism.
    Journal of neurochemistry, 2010, Volume: 112, Issue:2

    Topics: Amino Acids; Analysis of Variance; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Dipeptides; Dopamine; Dose-Response Relationship, Drug; Extinction, Psychological; Glutamate Carboxypeptidase II; Glutamic Acid; Male; Microdialysis; Microinjections; Neuroprotective Agents; Nucleus Accumbens; Organophosphorus Compounds; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Reinforcement Schedule; Self Administration; Sucrose; Sweetening Agents

2010
Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay.
    Amino acids, 2012, Volume: 42, Issue:6

    Topics: Animals; Cocaine; Glutamate Carboxypeptidase II; Glutamic Acid; Models, Animal; N-Methylaspartate; Organophosphorus Compounds; Pilocarpine; Planarians; Stereotyped Behavior

2012
S1 pocket of glutamate carboxypeptidase II: a new binding site for amyloid-β degradation.
    Biochemical and biophysical research communications, 2013, Sep-06, Volume: 438, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Binding Sites; Cell Line, Tumor; Dipeptides; Enzyme Inhibitors; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Mice; Mice, Transgenic; Molecular Docking Simulation; Mutagenesis, Site-Directed; Organophosphorus Compounds; Proteolysis

2013
Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis.
    The FEBS journal, 2016, Volume: 283, Issue:18

    Topics: Amino Acids; Animals; Astrocytes; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Organophosphorus Compounds; Protease Inhibitors; Rats, Inbred Lew; Receptors, Metabotropic Glutamate; Spinal Cord; Th1 Cells; Xanthenes

2016
A role for the locus coeruleus in the analgesic efficacy of N-acetylaspartylglutamate peptidase (GCPII) inhibitors ZJ43 and 2-PMPA.
    Molecular pain, 2017, Volume: 13

    Topics: Analgesics; Animals; Disease Models, Animal; Dopamine beta-Hydroxylase; Excitatory Amino Acid Agents; Formaldehyde; Glutamate Carboxypeptidase II; Glutamic Acid; Locus Coeruleus; Male; Norepinephrine; Organophosphorus Compounds; Pain; Rats; Rats, Sprague-Dawley; Urea

2017