glutamic acid has been researched along with pd 98059 in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 23 (74.19) | 29.6817 |
| 2010's | 7 (22.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kelly, A; Lynch, MA; Maguire, C; McGahon, B | 1 |
| Bar-Peled, O; Bristol, LA; Coccia, C; Griffin, JW; Ho, TW; Jin, L; Johnson, E; Li, Y; Milbrandt, J; Rothstein, JD | 1 |
| Gu, Z; Jiang, Q; Jing, G; Zhang, G | 1 |
| Czernik, AJ; Fienberg, AA; Greengard, P; Jovanovic, JN; Sihra, TS | 1 |
| Akaike, A; Honda, K; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Kubo, Y; Miyashita, T | 1 |
| Maher, P | 1 |
| Adamchik, Y; Baskys, A | 1 |
| Gu, Z; Jiang, Q; Zhang, G | 1 |
| Franco, R; Pasantes-Morales, H; Torres-Márquez, ME | 1 |
| Goodchild, AK; Pilowsky, PM; Seyedabadi, M | 1 |
| Carvalho, AP; Duarte, CB; Pereira, DB | 1 |
| Elliott-Hunt, CR; Grammatopoulos, DK; Hillhouse, EW; Kazlauskaite, J; Wilde, GJ | 1 |
| Ajima, R; K-Tsuzuku, J; Nakamura, T; Suzuki, T; Yamamoto, T; Yoshida, Y | 1 |
| Aoki, K; Badr, A; Tibbs, R; Yin, W; Zhang, J | 1 |
| Dorsa, DM; Mize, AL; Shapiro, RA | 1 |
| Lim, G; Mao, J; Sung, B | 1 |
| Benfenati, F; Bonanno, G; Giovedì, S; Raiteri, L; Raiteri, M | 1 |
| Abe, K; Misawa, M | 1 |
| Eisinger, DA; Schulz, R | 1 |
| Guirland, C; Kojima, M; Lu, B; Suzuki, S; Zheng, JQ | 1 |
| Papp, L; Sperlágh, B; Vizi, ES | 1 |
| Duan, XL; Kuang, F; Wang, BR; Xu, Z; Yan, H; Zhou, RH | 1 |
| Choi, HW; Choi, SM; Jung, JS; Kim, YW; Kwon, MS; Lee, JK; Park, SH; Seo, YJ; Suh, HW | 1 |
| Kondo, A; Matsuda, T; Togari, A; Tsunashima, Y | 1 |
| Bottum, KM; Karmarkar, SW; Krager, SL; Tischkau, SA | 1 |
| Fan, J; Ren, Y; Yin, G; Zhang, Z; Zhou, W | 1 |
| Cheng, Y; Ge, W; Geng, D; Geng, R; Li, J; Zhang, C; Zhang, M; Zhou, Y | 1 |
| Liu, Y; Lu, J; Meng, Q; Teng, L; Wang, D; Wang, Z; Xie, J | 1 |
| Guo, TQ; Liu, DP; Liu, Y; Lu, JH; Meng, QF; Teng, LS; Wang, D; Wang, ZY; Xie, J; Zhang, XL | 1 |
| Darvish-Ghane, S; Tian, Z; Yamanaka, M; Zhuo, M | 1 |
31 other study(ies) available for glutamic acid and pd 98059
| Article | Year |
|---|---|
Activation of p42 mitogen-activated protein kinase by arachidonic acid and trans-1-amino-cyclopentyl-1,3- dicarboxylate impacts on long-term potentiation in the dentate gyrus in the rat: analysis of age-related changes.
Topics: Aging; Animals; Arachidonic Acid; Cycloleucine; Dentate Gyrus; Drug Synergism; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Long-Term Potentiation; Male; Mitogen-Activated Protein Kinase 1; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1999 |
TGFbeta trophic factors differentially modulate motor axon outgrowth and protection from excitotoxicity.
Topics: Androstadienes; Animals; Axons; Chromones; Cloning, Molecular; Enzyme Inhibitors; Flavonoids; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Humans; Kinetics; Morpholines; Motor Neurons; Nerve Growth Factors; Nerve Tissue Proteins; Neurturin; Nodal Protein; Organ Culture Techniques; Rats; Recombinant Proteins; Spinal Cord; Transforming Growth Factor beta; Wortmannin | 2000 |
Diphosphorylation and involvement of extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons.
Topics: Animals; Apoptosis; Cell Culture Techniques; Cerebral Cortex; Chelating Agents; Dizocilpine Maleate; Egtazic Acid; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Glutamic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Neurotoxins; Phosphorylation; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Synapsins as mediators of BDNF-enhanced neurotransmitter release.
Topics: Animals; Brain-Derived Neurotrophic Factor; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Glutamic Acid; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Synapsins; Synaptic Transmission; Synaptosomes | 2000 |
Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Excitatory Amino Acid Antagonists; Flavonoids; Fulvestrant; Glutamic Acid; Morpholines; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley | 2000 |
Extracellular Ca2+ sensitivity of mGluR1alpha induces an increase in the basal cAMP level by direct coupling with Gs protein in transfected CHO cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium; Cell Size; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Fluorescent Dyes; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Isoquinolines; MAP Kinase Signaling System; Protein Kinase C; Receptors, Metabotropic Glutamate; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 2000 |
How protein kinase C activation protects nerve cells from oxidative stress-induced cell death.
Topics: Animals; Buthionine Sulfoximine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Homocysteine; Isoenzymes; Mice; Mitogen-Activated Protein Kinases; Neurons; Oxidative Stress; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Rats; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2001 |
Neuroprotective effects of extracellular glutamate are absent in hippocampal organotypic cultures treated with the amyloid peptide Abeta(25-35).
Topics: Alzheimer Disease; Amyloid beta-Peptides; Androstadienes; Animals; Cell Death; Culture Media, Serum-Free; Dentate Gyrus; Enzyme Inhibitors; Extracellular Space; Flavonoids; Fluorescent Dyes; Glutamic Acid; Hippocampus; MAP Kinase Signaling System; Microscopy, Confocal; Neuroprotective Agents; Organ Culture Techniques; Peptide Fragments; Phosphoinositide-3 Kinase Inhibitors; Propidium; Rats; Rats, Wistar; Receptors, Glutamate; Wortmannin | 2001 |
Nuclear translocation of extracellular signal-regulated kinases in neuronal excitotoxicity.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Cytoplasm; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Genistein; Glutamic Acid; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Neurotoxins; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sphingosine; Sulfonamides; Vanadates | 2001 |
Evidence for two mechanisms of amino acid osmolyte release from hippocampal slices.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Androstadienes; Angiogenesis Inhibitors; Animals; Aspartic Acid; Cyclooxygenase Inhibitors; Cytochalasins; Enzyme Inhibitors; Flavonoids; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Imidazoles; In Vitro Techniques; Mitogen-Activated Protein Kinases; Niflumic Acid; Nitrobenzoates; Osmolar Concentration; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyridines; Rats; Taurine; Tritium; Tyrphostins; Wortmannin | 2001 |
Differential role of kinases in brain stem of hypertensive and normotensive rats.
Topics: Androstadienes; Angiotensin II; Animals; Apnea; Blood Pressure; Brain Stem; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Hypertension; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Wortmannin | 2001 |
Non-specific effects of the MEK inhibitors PD098,059 and U0126 on glutamate release from hippocampal synaptosomes.
Topics: Animals; Butadienes; Calcium; Calcium Channel Blockers; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Hippocampus; Immunoblotting; In Vitro Techniques; Ionomycin; Ionophores; Male; Mitogen-Activated Protein Kinases; Nerve Endings; Nitriles; Potassium Chloride; Rats; Synaptosomes | 2002 |
Potential signalling pathways underlying corticotrophin-releasing hormone-mediated neuroprotection from excitotoxicity in rat hippocampus.
Topics: Animals; Cell Death; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Hippocampus; In Situ Hybridization, Fluorescence; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Neurotoxins; Organ Culture Techniques; Proto-Oncogene Proteins c-jun; Rats | 2002 |
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation.
Topics: 3T3 Cells; Alanine; Animals; Carrier Proteins; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cyclin D1; Enzyme Inhibitors; Flavonoids; G1 Phase; Glutamic Acid; Glutamine; Glutathione Transferase; Intracellular Signaling Peptides and Proteins; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Mapping; Phosphorylation; Phosphoserine; Plasmids; Protein Structure, Tertiary; ras Proteins; Resting Phase, Cell Cycle; S Phase; Serine; Time Factors; Transfection | 2002 |
Metabolic alterations in cerebrospinal fluid from double hemorrhage model of dogs.
Topics: Analysis of Variance; Animals; Caspase Inhibitors; Cerebral Hemorrhage; Disease Models, Animal; Dogs; Enzyme Inhibitors; Female; Flavonoids; Glucose; Glutamic Acid; Lactates; Male; Mitogen-Activated Protein Kinases; Pyruvic Acid; Time Factors; Vasospasm, Intracranial | 2002 |
Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway.
Topics: Animals; Cell Line; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Flavonoids; Fulvestrant; Glutamic Acid; Hippocampus; Humans; Mitogen-Activated Protein Kinases; Mutation; Neuroprotective Agents; Oxidative Stress; Rats; Receptors, Estrogen; Transfection | 2003 |
Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats.
Topics: Amino Acid Transport System X-AG; Animals; Behavior, Animal; Biological Transport; Carbazoles; Constriction; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Transporter 2; Flavonoids; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hyperalgesia; Indole Alkaloids; Kinetics; Male; Mitogen-Activated Protein Kinases; Neuralgia; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Riluzole; Spinal Cord; Symporters; Up-Regulation | 2003 |
Cellular mechanisms of the acute increase of glutamate release induced by nerve growth factor in rat cerebral cortex.
Topics: Animals; Animals, Newborn; Anticoagulants; Benzylamines; Blotting, Western; Caffeine; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Central Nervous System Stimulants; Cerebral Cortex; Clonazepam; Dantrolene; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Fura-2; Glutamic Acid; Heparin; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Mitogen-Activated Protein Kinase Kinases; Muscle Relaxants, Central; Nerve Growth Factor; Peptide Fragments; Phosphoprotein Phosphatases; Phosphorylation; Potassium; Proto-Oncogenes; Rats; Rats, Sprague-Dawley; Receptor, trkA; Sulfonamides; Synapsins; Synaptosomes; Thiazepines | 2003 |
The extracellular signal-regulated kinase cascade suppresses amyloid beta protein-induced promotion of glutamate clearance in cultured rat cortical astrocytes.
Topics: Adenosine Monophosphate; Amino Acid Transport System X-AG; Amyloid beta-Peptides; Animals; Animals, Newborn; Antioxidants; Astrocytes; Blotting, Western; Butadienes; Cells, Cultured; Cerebral Cortex; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Extracellular Space; Flavonoids; Glutamic Acid; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Protein Synthesis Inhibitors; Rats | 2003 |
Extracellular signal-regulated kinase/mitogen-activated protein kinases block internalization of delta-opioid receptors.
Topics: Arrestins; Biological Transport; Cells, Cultured; Drug Interactions; Endocytosis; Enzyme Activation; Etorphine; Flavonoids; Glutamic Acid; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morphine; Naphthalenes; Phosphoproteins; Phosphorylation; Receptors, Opioid, delta; Tyrphostins | 2004 |
Lipid rafts mediate chemotropic guidance of nerve growth cones.
Topics: Animals; Antibodies; Antigens; Blotting, Western; Brain Stem; Brain-Derived Neurotrophic Factor; Cell Adhesion Molecules; Cells, Cultured; Cholera Toxin; Cholesterol; Cytoskeletal Proteins; DCC Receptor; Drug Interactions; Filipin; Flavonoids; Fluorescent Antibody Technique; Glutamic Acid; Growth Cones; Image Processing, Computer-Assisted; Membrane Microdomains; Mucin-5B; Mucins; Nerve Growth Factors; Netrin-1; Neurons; Neuropilin-1; Peptides; Receptor, trkB; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Semaphorins; Signal Transduction; Statistics, Nonparametric; Tumor Suppressor Proteins; Xenopus | 2004 |
P2X7 receptor mediated phosphorylation of p38MAP kinase in the hippocampus.
Topics: Animals; Blotting, Western; Flavonoids; Glutamic Acid; Hippocampus; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Purinergic P2 Receptor Agonists; Pyridines; Receptors, Purinergic P2; Receptors, Purinergic P2X7 | 2007 |
Role of extracellular signal-regulated kinase in glutamate-stimulated apoptosis of rat retinal ganglion cells.
Topics: Animals; Apoptosis; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fluorescent Antibody Technique, Indirect; Glutamic Acid; Immunoenzyme Techniques; In Situ Nick-End Labeling; Injections; Phosphorylation; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Signal Transduction; Vitreous Body | 2007 |
Differential expression of phosphorylated Ca2+/calmodulin-dependent protein kinase II and phosphorylated extracellular signal-regulated protein in the mouse hippocampus induced by various nociceptive stimuli.
Topics: Acetic Acid; Analysis of Variance; Animals; Behavior, Animal; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Formaldehyde; Gene Expression Regulation, Enzymologic; Glutamic Acid; Hippocampus; Interleukin-1beta; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Phosphorylation; Protein Kinase Inhibitors; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha | 2008 |
Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts.
Topics: Adult; Anticoagulants; Bone Neoplasms; Cell Line; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Humans; Imidazoles; Interleukin-1; Interleukin-1beta; Male; Mitogen-Activated Protein Kinase Kinases; Nitrobenzenes; Osteoblasts; Osteocalcin; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Pregnane X Receptor; Protein Kinase Inhibitors; Pyridines; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Sulfonamides; Vitamin K; Vitamins; Warfarin; Young Adult | 2010 |
ERK/MAPK is essential for endogenous neuroprotection in SCN2.2 cells.
Topics: Animals; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Caspase 3; Cell Line; Dizocilpine Maleate; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Glutamic Acid; GPI-Linked Proteins; Immunohistochemistry; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Models, Neurological; Neurons; Neuropeptides; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; Suprachiasmatic Nucleus | 2011 |
The release of glutamate from cortical neurons regulated by BDNF via the TrkB/Src/PLC-γ1 pathway.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cerebral Cortex; Chromones; Embryo, Mammalian; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Glutamic Acid; Indole Alkaloids; Morpholines; Neurons; Phospholipase C gamma; Phosphorylation; Primary Cell Culture; Pyrimidines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, trkB; Signal Transduction; src-Family Kinases | 2013 |
The inhibition of ERK activation mediates the protection of necrostatin-1 on glutamate toxicity in HT-22 cells.
Topics: Animals; Butadienes; Cell Death; Cell Line; Cell Survival; Excitatory Amino Acid Antagonists; Flavonoids; Glutamic Acid; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors | 2013 |
Liquiritin modulates ERK‑ and AKT/GSK‑3β‑dependent pathways to protect against glutamate‑induced cell damage in differentiated PC12 cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cytochromes c; Extracellular Signal-Regulated MAP Kinases; Flavanones; Flavonoids; Glucosides; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Membrane Potential, Mitochondrial; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction | 2014 |
ERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Differentiation; Cell Survival; Chromones; Cytochromes c; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Glycyrrhizic Acid; MAP Kinase Signaling System; Mitochondria; Morpholines; Neuroprotective Agents; PC12 Cells; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction | 2014 |
Pre-LTP requires extracellular signal-regulated kinase in the ACC.
Topics: Animals; Butadienes; Excitatory Postsynaptic Potentials; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutamic Acid; Gyrus Cinguli; Long-Term Potentiation; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Nitriles; Protein Biosynthesis; Protein Kinase Inhibitors; Synapses; Transcription, Genetic | 2016 |