glutamic acid has been researched along with paclitaxel in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (8.82) | 18.2507 |
| 2000's | 15 (44.12) | 29.6817 |
| 2010's | 13 (38.24) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Mattson, MP | 1 |
| Audebert, S; Denoulet, P; Desbruyères, E; Eddé, B; Gros, F; Gruszczynski, C; Koulakoff, A | 1 |
| Boyle, FM; Shenfield, GM; Wheeler, HR | 1 |
| Cushman, M; Hamel, E; Mohanakrishnan, AK; Verdier-Pinard, P; Wang, Z | 1 |
| Keith, CH; Kisaalita, WS; Wilson, MT | 1 |
| Buchmiller, LM; Charnsangavej, C; Hunter, N; Ke, S; Li, C; Milas, L; Tansey, W; Wallace, S; Wu, QP | 1 |
| Gundersen, GG; Lin, SX; Maxfield, FR | 1 |
| Buck, KB; Zheng, JQ | 1 |
| Kawasaki, K; Nishijima, M; Nogawa, H | 1 |
| Arce, CA; Barra, HS; Bisig, CG; Contín, MA; Purro, SA | 1 |
| Arce, CA; Barra, HS; Casale, CH; Previtali, G; Serafino, JJ | 1 |
| Aravindan, N; Cata, JP; Chen, JH; Dougherty, PM; Shaw, AD; Weng, HR | 1 |
| Fallon, JR; Taylor, AB | 1 |
| Annable, T; Greenberger, LM; Hari, M; Loganzo, F; Morilla, DB; Musto, S; Nettles, JH; Snyder, JP; Tan, X | 1 |
| Curran, DP; Cushman, M; Day, BW; Ghosh, AK; Hamel, E; Jung, MK; Miller, JH; Nicolaou, KC; Northcote, PT; Paterson, I; Sorensen, EJ | 1 |
| Horwitz, SB; Wiesen, KM; Xia, S; Yang, CP | 1 |
| Furusawa, K; Kobayashi, Y; Mizoguchi, T; Nakamichi, Y; Naramoto, H; Takahashi, M; Takahashi, N; Udagawa, N; Uehara, S; Uematsu, T; Yamaoka, M; Yamashita, T; Yang, S | 1 |
| Andras, M; Dabby, R; Fishman, A; Gadoth, N; Karmon, Y; Levavi, H; Levi, T; Loven, D; Sabach, G; Zart, R | 1 |
| Fujiwara, T; Morimoto, K | 1 |
| Bronich, TK; Cohen, SM; Desale, SS; Kabanov, AV; Zhao, Y | 1 |
| Angeletti, RH; Berezniuk, I; Fricker, LD; Ikegami, K; Lyons, PJ; Setou, M; Sironi, JJ; Xiao, H | 1 |
| Chen, X; Deng, M; Li, M; Liu, H; Lv, S; Song, W; Sun, H; Tang, Z | 1 |
| Chong, Y; Choo, H; Kim, MK | 1 |
| Cao, W; Gao, G; Gu, Y; Li, S; Liu, M; Shan, L; Wu, C; Xu, L; Zhao, L | 1 |
| Deng, C; Meng, F; Wu, J; Zhang, J; Zhong, Z | 1 |
| Kapoor, S; Kumar Santra, M; Naaz, A; Panda, D; Rai, A | 1 |
| Sun, T; Wang, X; Wang, Z; Xie, Z; Zhuang, M | 1 |
| Chang, YC; Chen, HY; Cheng, MY; Chuang, CF; Chung, HW; Fu, CC; Ho, HH; Hsu, YH; Huang, TK; Leong, WC; Yang, WC | 1 |
| Ali, MW; Gao, M; Hooks, SB; Li, F; Maixner, DW; Weng, HR; Yadav, R; Yan, X | 1 |
| Chen, C; Cui, X; Guo, Z; Lin, D; Wang, S; Xie, C; Zhao, Y; Zhao, Z; Zhou, J | 1 |
| Fan, J; Ju, J; Li, H; Qian, Y; Shan, L; Wang, J; Wang, W; Zhu, G | 1 |
| Cheung, CW; Gu, P; Iadarola, M; Saligan, L; Ti, LK; Wang, XM; Wong, SSC | 1 |
| Ba, X; Hao, Y; Huang, Z; Jiang, C; Jin, G; Wang, J; Wu, J; Yang, S | 1 |
1 trial(s) available for glutamic acid and paclitaxel
| Article | Year |
|---|---|
Long-term glutamate supplementation failed to protect against peripheral neurotoxicity of paclitaxel.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Double-Blind Method; Female; Glutamic Acid; Humans; Middle Aged; Neurotoxicity Syndromes; Ovarian Neoplasms; Paclitaxel; Peripheral Nervous System Diseases; Treatment Outcome | 2009 |
33 other study(ies) available for glutamic acid and paclitaxel
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons.
Topics: Alkaloids; Animals; Calcimycin; Calcium; Cells, Cultured; Colchicine; Embryo, Mammalian; Fura-2; Glutamates; Glutamic Acid; Hippocampus; Immunohistochemistry; Kinetics; Microtubules; Neurons; Paclitaxel; Pyramidal Tracts; Rats; tau Proteins | 1992 |
Reversible polyglutamylation of alpha- and beta-tubulin and microtubule dynamics in mouse brain neurons.
Topics: Animals; Antibodies, Monoclonal; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Immunoblotting; Mice; Microtubules; Neurons; Nocodazole; Paclitaxel; Polymers; Stereoisomerism; Tubulin | 1993 |
Amelioration of experimental cisplatin and paclitaxel neuropathy with glutamate.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cisplatin; Female; Gait; Glutamic Acid; Hot Temperature; Mammary Neoplasms, Experimental; Motor Activity; Paclitaxel; Peripheral Nervous System Diseases; Rats; Sensory Thresholds | 1999 |
A steroid derivative with paclitaxel-like effects on tubulin polymerization.
Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents, Phytogenic; Biopolymers; Cattle; Estradiol; Glutamic Acid; Microtubule-Associated Proteins; Paclitaxel; Tubulin; Tubulin Modulators | 2000 |
Glutamate-induced changes in the pattern of hippocampal dendrite outgrowth: a role for calcium-dependent pathways and the microtubule cytoskeleton.
Topics: Antineoplastic Agents; Calcium; Cell Survival; Cells, Cultured; Cysteine Proteinase Inhibitors; Cytoskeleton; Dendrites; Dipeptides; Enzyme Inhibitors; Fluoresceins; Glutamic Acid; Glycoproteins; Growth Cones; Hippocampus; Imidazoles; Microscopy, Fluorescence; Microtubule Proteins; Microtubules; Neurons; Nocodazole; Paclitaxel | 2000 |
Potentiation of ovarian OCa-1 tumor radioresponse by poly (L-glutamic acid)-paclitaxel conjugate.
Topics: Animals; Dose-Response Relationship, Radiation; Drug Combinations; Female; Glutamic Acid; Mice; Ovarian Neoplasms; Paclitaxel; Radiation-Sensitizing Agents; Radiobiology; Radiotherapy Dosage; Time Factors; Tumor Cells, Cultured | 2000 |
Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin.
Topics: Animals; Antibodies; Cell Compartmentation; Cell Line; Cell Membrane; Centrioles; CHO Cells; Cricetinae; Endocytosis; Fluorescent Antibody Technique; Glutamic Acid; HeLa Cells; Humans; Kinesins; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Protein Transport; Transferrin; Transport Vesicles; Tyrosine | 2002 |
Growth cone turning induced by direct local modification of microtubule dynamics.
Topics: Actins; Animals; Antineoplastic Agents, Phytogenic; Cells, Cultured; Cytoskeleton; Diffusion; Extracellular Space; Glutamic Acid; Growth Cones; Microtubules; Nerve Growth Factors; Netrin-1; Paclitaxel; Tumor Suppressor Proteins; Vinblastine; Xenopus | 2002 |
Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 by alanine-scanning mutagenesis.
Topics: Alanine; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antigens, Ly; Aspartic Acid; Cell Line; Cell Membrane; Drosophila Proteins; Glutamic Acid; Humans; Ligands; Lipopolysaccharide Receptors; Lipopolysaccharides; Lymphocyte Antigen 96; Membrane Glycoproteins; Mice; Mutagenesis, Site-Directed; Paclitaxel; Receptors, Cell Surface; Toll-Like Receptor 4; Toll-Like Receptors; Transfection | 2003 |
Inhibitors of protein phosphatase 1 and 2A decrease the level of tubulin carboxypeptidase activity associated with microtubules.
Topics: Animals; Carboxypeptidases; Catalase; COS Cells; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Immunoblotting; Microscopy, Fluorescence; Microtubules; Okadaic Acid; Paclitaxel; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Phosphatase 1; Temperature; Tyrosine | 2003 |
Regulation of acetylated tubulin/Na+,K+-ATPase interaction by L-glutamate in non-neural cells: involvement of microtubules.
Topics: Acetylation; Amino Acid Transport System X-AG; Animals; Cell Line; Glutamic Acid; Humans; Microtubules; Nocodazole; Paclitaxel; Sodium; Sodium-Potassium-Exchanging ATPase; Tubulin | 2005 |
Spinal glial glutamate transporters downregulate in rats with taxol-induced hyperalgesia.
Topics: Amino Acid Transport System X-AG; Animals; Antineoplastic Agents, Phytogenic; Cell Communication; Disease Models, Animal; Down-Regulation; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hyperalgesia; Male; Neuroglia; Nociceptors; Paclitaxel; Peripheral Nervous System Diseases; Posterior Horn Cells; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Symporters; Synaptic Transmission | 2005 |
Dendrites contain a spacing pattern.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cells, Cultured; Cerebellum; Dendrites; Diffusion; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Mice; Microtubule-Associated Proteins; Microtubules; Morphogenesis; Neocortex; Neurons; Nocodazole; Paclitaxel; Potassium Chloride; Pyramidal Cells; Rats; Sodium Channel Blockers; Staining and Labeling; Tetrodotoxin; Valine | 2006 |
Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents, Phytogenic; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Squamous Cell; Cell Line, Tumor; Docetaxel; Drug Resistance, Neoplasm; Epothilones; Glutamic Acid; Humans; Mice; Mice, Nude; Microtubules; Paclitaxel; Point Mutation; Protein Conformation; Taxoids; Tubulin; Verapamil | 2006 |
Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Drug Synergism; Glutamic Acid; Guanosine Triphosphate; Humans; Lactones; Macrolides; Microtubule-Associated Proteins; Models, Molecular; Paclitaxel; Taxoids; Temperature; Tubulin; Tumor Cells, Cultured | 2006 |
Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation.
Topics: Adenocarcinoma; Alkanes; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carbamates; Cell Line, Tumor; Cell Survival; Dimerization; Docetaxel; Drug Resistance, Neoplasm; Epothilones; Fluorescent Antibody Technique, Indirect; Glutamic Acid; Glycine; Humans; Lactones; Models, Molecular; Mutation, Missense; Paclitaxel; Protein Structure, Quaternary; Pyrones; Taxoids; Transfection; Tubulin; Tubulin Modulators | 2007 |
Docetaxel inhibits bone resorption through suppression of osteoclast formation and function in different manners.
Topics: Actins; Animals; Antineoplastic Agents; Bone and Bones; Bone Marrow Cells; Bone Resorption; Calcitriol; Cell Survival; Cells, Cultured; Coculture Techniques; Dinoprostone; Docetaxel; Glutamic Acid; Humans; Macrophages; Male; Mice; Osteoblasts; Osteoclasts; Paclitaxel; RANK Ligand; Taxoids | 2009 |
Inhibition of p53 transactivation functionally interacts with microtubule stabilization to suppress excitotoxicity-induced axon degeneration.
Topics: Animals; Axons; Benzothiazoles; Cells, Cultured; Dynactin Complex; Glutamic Acid; Hippocampus; Microtubule-Associated Proteins; Microtubules; Mitochondria; Mitochondrial Diseases; Nerve Degeneration; Neurotoxins; Paclitaxel; Rats; Rats, Wistar; Toluene; Transcriptional Activation; Tumor Suppressor Protein p53 | 2012 |
Biodegradable hybrid polymer micelles for combination drug therapy in ovarian cancer.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin; Delayed-Action Preparations; Female; Glutamic Acid; Humans; Mice; Mice, Nude; Micelles; Ovarian Neoplasms; Ovary; Paclitaxel; Phenylalanine; Polyethylene Glycols | 2013 |
Cytosolic carboxypeptidase 5 removes α- and γ-linked glutamates from tubulin.
Topics: Animals; Carboxypeptidases; Glutamic Acid; Mice; Microtubules; Paclitaxel; Sf9 Cells; Spodoptera; Tubulin; Tubulin Modulators | 2013 |
Polypeptide-based combination of paclitaxel and cisplatin for enhanced chemotherapy efficacy and reduced side-effects.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Death; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Synergism; Endocytosis; Glutamic Acid; Humans; Immunohistochemistry; Inhibitory Concentration 50; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Micelles; Paclitaxel; Peptides; Polyethylene Glycols; Proton Magnetic Resonance Spectroscopy; Tumor Burden | 2014 |
Water-soluble and cleavable quercetin-amino acid conjugates as safe modulators for P-glycoprotein-based multidrug resistance.
Topics: Alanine; Amino Acids; Antineoplastic Agents; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Glutamic Acid; Humans; Microscopy, Confocal; Models, Chemical; Molecular Structure; Paclitaxel; Quercetin; Verapamil; Vinblastine | 2014 |
Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Arginine; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Drug Carriers; Female; Fluorescein-5-isothiocyanate; Folic Acid; Glutamic Acid; HEK293 Cells; Humans; Lethal Dose 50; Male; Mice; Mice, Nude; Molecular Weight; Neoplasms; Paclitaxel; Prodrugs; Solubility; Toxicity Tests, Acute; Xenograft Model Antitumor Assays | 2015 |
Vitamin E-Oligo(methyl diglycol l-glutamate) as a Biocompatible and Functional Surfactant for Facile Preparation of Active Tumor-Targeting PLGA Nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Breast Neoplasms; Cell Survival; Drug Carriers; Drug Delivery Systems; Female; Glutamic Acid; Glycols; Humans; Lactic Acid; Mice; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents; Tumor Cells, Cultured; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Enhanced stability of microtubules contributes in the development of colchicine resistance in MCF-7 cells.
Topics: Acetylation; Breast Neoplasms; Colchicine; Drug Resistance, Neoplasm; Glutamic Acid; Humans; MCF-7 Cells; Microtubules; Mutation; Paclitaxel; Tubulin | 2017 |
Self-assembly of glutamic acid linked paclitaxel dimers into nanoparticles for chemotherapy.
Topics: Antineoplastic Agents; Cell Survival; Dimerization; Dynamic Light Scattering; Glutamic Acid; HeLa Cells; Humans; MCF-7 Cells; Microscopy, Confocal; Nanoparticles; Paclitaxel; Solubility | 2017 |
A compartmentalized culture device for studying the axons of CNS neurons.
Topics: Animals; Axons; Cell Culture Techniques; Cells, Cultured; Dendrites; Dimethylpolysiloxanes; Embryo, Mammalian; Glutamic Acid; Microfluidic Analytical Techniques; Microscopy, Fluorescence; Microtubules; Neurons; Paclitaxel; Rats | 2017 |
Interleukin-1beta released by microglia initiates the enhanced glutamatergic activity in the spinal dorsal horn during paclitaxel-associated acute pain syndrome.
Topics: Animals; Antineoplastic Agents; Calcium; Excitatory Postsynaptic Potentials; Glutamic Acid; Interleukin-1beta; Male; Mice; Mice, Knockout; Microglia; Miniature Postsynaptic Potentials; Paclitaxel; Pain; Pain Measurement; Rats; Spinal Cord Dorsal Horn | 2019 |
Dual-active targeting liposomes drug delivery system for bone metastatic breast cancer: Synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Breast Neoplasms; Cell Proliferation; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Glutamic Acid; Humans; Ligands; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Oligopeptides; Paclitaxel; Tumor Cells, Cultured | 2019 |
Targeted Prodrug-Based Self-Assembled Nanoparticles for Cancer Therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Drug Delivery Systems; Female; Fluorescein-5-isothiocyanate; Glucosamine; Glutamic Acid; Humans; Mice, Inbred BALB C; Nanoparticles; Paclitaxel; Prodrugs; Xenograft Model Antitumor Assays | 2020 |
Dysregulation of EAAT2 and VGLUT2 Spinal Glutamate Transports via Histone Deacetylase 2 (HDAC2) Contributes to Paclitaxel-induced Painful Neuropathy.
Topics: Animals; Excitatory Amino Acid Transporter 2; Glutamic Acid; Histone Deacetylase 2; Male; Paclitaxel; Pain; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Vesicular Glutamate Transport Protein 2 | 2020 |
Selective activation of metabotropic glutamate receptor 7 blocks paclitaxel-induced acute neuropathic pain and suppresses spinal glial reactivity in rats.
Topics: Acute Pain; Allosteric Regulation; Animals; Benzhydryl Compounds; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Neuralgia; Paclitaxel; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord | 2021 |