glutamic acid has been researched along with oxadiazoles in 179 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 139 (77.65) | 18.7374 |
| 1990's | 22 (12.29) | 18.2507 |
| 2000's | 11 (6.15) | 29.6817 |
| 2010's | 7 (3.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johansson, BB; Westergren, I | 1 |
| Lasater, EM | 1 |
| Köhler, M; Seeburg, PH; Sommer, B; Sprengel, R | 1 |
| Cha, JH; Drejer, J; Honoré, T; Nielsen, EO; Young, AB | 1 |
| Cooper, MS; Cornell-Bell, AH; Finkbeiner, SM; Smith, SJ | 1 |
| Jahr, CE; Lester, RA | 1 |
| Glaum, SR; Miller, RJ; Scholz, WK | 1 |
| Cox, JA; Felder, CC; Henneberry, RC | 1 |
| Cha, JH; Makowiec, RL; Penney, JB; Young, AB | 1 |
| Morrow, C; Murphy, S; Pearce, B | 1 |
| Fujiwara, M; Ninomiya, H; Taniguchi, T | 1 |
| Nistri, A; Sivilotti, L; Welsh, DM | 1 |
| Bockaert, J; Dumuis, A; Oomagari, K; Pin, JP; Sebben, M | 1 |
| Jope, RS; Li, XH; Song, L | 1 |
| Alexander, SP; Hill, SJ; Kendall, DA | 1 |
| Albin, RL; Cha, JH; Gilman, S; Makowiec, RL; Young, AB | 1 |
| Dolphin, AC; Huston, E; Scott, RH | 1 |
| Ishida, M; Shinozaki, H | 2 |
| Michl, J; Ujec, E; Vlachová, V; Vyklický, L; Vyskocil, F | 1 |
| Aanonsen, LM; Wilcox, GL | 1 |
| Jordan, W; Sutor, B; Zieglgänsberger, W | 1 |
| Cherubini, E; King, AE; Nistri, A | 1 |
| Dudel, J; Franke, C; Hatt, H; Ramsey, RL; Usherwood, PN | 1 |
| Berry, BW; Boland, LM; Dingledine, R; Hoch, DB | 1 |
| Cull-Candy, SG; Howe, JR; Ogden, DC | 1 |
| Ashford, ML; Boden, P; Ramsey, RL; Usherwood, PN | 1 |
| Cull-Candy, SG; Gallo, V; Usowicz, MM | 1 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Gallo, V; Giovannini, C; Levi, G; Suergiu, R | 2 |
| Grantyn, R; Perouansky, M | 1 |
| Fonnum, F; Syvertsen, C | 1 |
| Araneda, R; Bustos, G | 1 |
| Christensen, BN; O'Dell, TJ | 1 |
| Clow, DW; Jhamandas, K | 1 |
| O'Dell, TJ | 1 |
| Kouvelas, ED; Michalodimitrakis, M; Mitsacos, A; Plaitakis, A; Tsiotos, P; Voukelatou, G | 1 |
| Avola, R; Bruno, V; Condorelli, DF; Ingrao, F; Magri, G; Nicoletti, F | 1 |
| Ogita, K; Yoneda, Y | 2 |
| Cha, JH; Greenamyre, JT; Hollingsworth, ZR; Young, AB | 1 |
| Guiramand, J; Nourigat, A; Recasens, M; Sassetti, I | 1 |
| Abbott, NJ; Hassan, S; Lieberman, EM | 1 |
| Miller, RJ; Murphy, SN | 1 |
| Baba, A; Iwata, H; Kihara, T; Sawada, T | 1 |
| King, AE; Thompson, SW | 1 |
| Facci, L; Guidolin, D; Leon, A; Milani, D; Skaper, SD | 1 |
| Ben-Ari, Y; Represa, A; Tremblay, E | 1 |
| Baba, A; Iwata, H; Koyama, Y | 1 |
| Crépel, F; Hicks, TP; Krupa, M | 1 |
| Guiramand, J; Recasens, M; Sassetti, I | 1 |
| Gallo, V; Levi, G; Patrizio, M | 1 |
| Herranz, AS; Herreras, O; Martín del Río, R; Menéndez, N; Solis, JM | 1 |
| Anis, NA; Eldefrawi, AT; Eldefrawi, ME; Gant, DB; Konno, K; Miledi, R; Ragsdale, D | 1 |
| Aldinio, C; Leon, A; Nicoletti, F; Seren, MS; Zanoni, R | 1 |
| Dye, J; Heiligenberg, W; Kawasaki, M; Keller, CH | 1 |
| Bredt, DS; Snyder, SH | 1 |
| Akerman, KE; Enkvist, MO; Holopainen, I | 2 |
| Hornfeldt, CS; Larson, AA | 1 |
| Anwyl, R | 1 |
| Furuya, S; Ohmori, H; Shigemoto, T; Sugiyama, H | 1 |
| Coyle, JT; Miyamoto, M; Murphy, TH; Sastre, A; Schnaar, RL | 1 |
| Sato, H; Yamamoto, C | 1 |
| Arenson, MS; Nistri, A | 1 |
| Arenson, MS; King, A; Nistri, A | 1 |
| Harrison, NL; Simmonds, MA | 1 |
| Ishida, AT; Neyton, J | 1 |
| Kawai, N; Saito, M | 1 |
| King, AE; Nistri, A; Rovira, C | 1 |
| Christensen, BN; Hals, G; Shingai, R | 1 |
| Collins, JF; Meldrum, BS; Turski, L | 1 |
| Sawada, S; Yamamoto, C | 2 |
| Homma, S | 1 |
| Higashima, M; Sawada, S; Yamamoto, C | 1 |
| Coyle, JT; Koller, KJ | 1 |
| Goldberg, O; Teichberg, VI | 2 |
| Davies, J; Quinlan, JE | 1 |
| Chuang, DM; Costa, E; Iadarola, MJ; Meek, JL; Nicoletti, F; Roth, BL | 1 |
| Dubas, F; Florey, E; Hanlon, RT | 1 |
| Hablitz, JJ | 1 |
| Baudry, M; Cummins, JT; Kessler, M; Lynch, G; Way, S | 1 |
| Kiskin, NI; Krishtal, OA | 1 |
| Costa, E; Iadarola, MJ; Nicoletti, F; Wroblewski, JT | 1 |
| Drejer, J; Honoré, T; Meier, E; Schousboe, A | 1 |
| Cha, JH; Dowling, JE; O'Brien, DR | 1 |
| Jürgens, U; Richter, K | 1 |
| Carpenter, DO; ffrench-Mullen, JM; Hori, N | 1 |
| Crepel, F; Gardette, R | 1 |
| Bobbin, RP; Jenison, GL; Winbery, S | 1 |
| Blakely, RD; Coyle, JT; Ory-Lavollée, L; Thompson, RC | 1 |
| Gullak, MF; Mena, EE; Pagnozzi, MJ | 1 |
| Cuenod, M; Do, KQ; Herrling, PL; Streit, P; Turski, WA | 1 |
| Choi, DW; Koh, JY; Peters, S | 2 |
| Cross, A; Skan, W; Slater, P | 1 |
| Quinn, MR; Spraguer, PA | 1 |
| Costa, E; Nicoletti, F; Wroblewski, JT | 1 |
| Mayer, ML; Westbrook, GL | 2 |
| Arqueros, L; Bustos, G; Fiedler, JL | 1 |
| Crepel, F; Dupont, JL; Gardette, R | 2 |
| Akaike, N; Kawai, N; Kiskin, NI; Kljuchko, EM; Krishtal, OA | 1 |
| Gulat-Marnay, C; Lafitte, A; Schwartz, JC; Vargas, F | 1 |
| Murphy, DE; Snowhill, EW; Williams, M | 1 |
| Cotman, CW; Harris, EW; Stevens, DR | 1 |
| Crepel, F; Debono, M; Hamon, B | 1 |
| Grantyn, R; Hablitz, JJ; Lux, HD; Perouansky, M | 1 |
| Greenamyre, JT; Olson, JM; Penney, JB; Young, AB | 1 |
| Alho, H; Costa, E; Eva, C; Fadda, E; Nicoletti, F; Wroblewski, JT | 1 |
| Arlis, S; Balm, M; Coyle, JT; Drucker, H; Zaczek, R | 1 |
| Crepel, F; Gardette, R; Krupa, M | 1 |
| Dryer, SE | 1 |
| Cunningham, JR; Neal, MJ; Stone, S; Witkovsky, P | 1 |
| Cowburn, RF; Hardy, JA; Roberts, PJ | 1 |
| Engberg, I; Flatman, JA; Nedergaard, S | 1 |
| Kihara, M; Kubo, T | 1 |
| Cha, JH; Greenamyre, JT; Nielsen, EO; Penney, JB; Young, AB | 1 |
| Errami, M; Nieoullon, A | 1 |
| Kaneko, A; Tachibana, M | 1 |
| Canonico, PL; Catania, MV; Favit, A; Nicoletti, F | 1 |
| King, AE; Thompson, SW; Urban, L; Woolf, CJ | 1 |
| Astier, H; Tapia-Arancibia, L | 1 |
| Raigorodsky, G; Urca, G | 1 |
| Benavides, J; Claustre, Y; Scatton, B | 1 |
| Johnson, BG; Schoepp, DD | 1 |
| Lovinger, DM; Weight, FF | 1 |
| Davidoff, RA; Hackman, JC; Wohlberg, CJ | 1 |
| Davidson, N; Fong, TM; Lester, HA | 1 |
| Hirono, C; Ito, I; Sugiyama, H; Yamagishi, S | 1 |
| Carpenter, DO; Hori, N | 1 |
| Coyle, JT; Murphy, TH; Sastre, A; Schnaar, RL | 1 |
| Backus, KH; Kettenmann, H; Schachner, M; Sontheimer, H | 1 |
| Gration, KA; Lambert, JJ; Ramsey, RL; Rand, RP; Usherwood, PN | 1 |
| Shinozaki, H | 1 |
| Evans, RH; Smith, DA | 1 |
| McNamara, JO; Nadler, JV; Savage, DD; Werling, LL | 2 |
| Donaldson, PL; Duce, IR; Usherwood, PN | 1 |
| Cotman, CW; Fagg, GE; Foster, AC; Mena, EE | 1 |
| Doman, KA; Nadler, JV; Werling, LL | 1 |
| Donzanti, BA; Uretsky, NJ | 1 |
| Nadler, JV; Werling, LL | 1 |
| Kamp, CW; Morgan, WW | 1 |
| Collingridge, GL; Kehl, SJ; Loo, R; McLennan, H | 1 |
| Kerkut, GA; Mat Jais, AM; Walker, RJ | 1 |
| Ariel, M; Dowling, JE; Lasater, EM; Mangel, SC | 1 |
| Agnati, LF; Celani, MF; Fuxe, K; Martire, M; Zini, I; Zoli, M | 1 |
| Crepel, F; Dupont, JL; Fournier, E; Gardette, R | 1 |
| Arenson, MS; Berti, C; King, AE; Nistri, A | 1 |
| Fagg, GE; Matus, A | 1 |
| Joëls, M; Urban, IJ | 1 |
| Maura, G; Raiteri, M | 1 |
| Carvalho, AP; Carvalho, CM; Sequeira, SM | 1 |
| Marcoli, M; Maura, G; Munari, C; Raiteri, M; Ruelle, A | 1 |
| Bechtel, WD; Brambilla, A; Brenner, M; Ceci, A; Ensinger, HA; Palluk, R; Sagrada, A; Weiser, T; Wienrich, M | 1 |
| Kawamata, T; Omote, K | 1 |
| Anraku, M; Ichinose, M; Sawada, M | 1 |
| Akiba, I; Barsoumian, E; Brenner, M; Iizuka, M; Nishimura, S; Palluk, R; Steinhäuser, C; Weiser, T; Wienrich, M; Zhou, M | 1 |
| Hamon, M; Laguzzi, R; Maisonneuve, B; Sévoz-Couche, C | 1 |
| Fowler, L; Pearce, B; Watts, J; Whitton, PS | 1 |
| Bennett, VJ; Papaconstandinou, NA; Reynolds, IJ; Rintoul, GL | 1 |
| Amatore, C; Arbault, S; Cauli, B; Geoffroy, H; Guille, M; Hamel, E; Rancillac, A; Rossier, J; Tong, XK | 1 |
| Kasparov, S; Paton, JF; Wang, S | 1 |
| Bassilana, F; Cortes-Cros, M; Craveiro, LM; Dev, KK; Guerini, D; Mullershausen, F; Osinde, M; Schwab, ME; Seuwen, K; Shin, Y; Sivasankaran, R; Thallmair, M; Wishart, WL | 1 |
| Corrêa, FM; Resstel, LB; Tavares, RF | 1 |
| Alves, PM; Queiroga, CS; Vieira, HL | 1 |
| Bradley, SJ; Challiss, RA; Watson, JM | 1 |
| Amir, A; Contreras-Sanz, A; Foti, A; Fruttero, R; Gasco, A; Giordano, C; Hansen, KB; Johansen, TN; Lolli, ML; Nielsen, B; Pickering, DS; Rolando, B | 1 |
| Busnardo, C; Correa, FM; Crestani, CC; Resstel, LB; Tavares, RF | 1 |
| Ding, K; Duan, L; Li, H; Li, Y; Liu, X; Peng, L; Shen, M; Yan, J | 1 |
| Jardemark, K; Malmerfelt, A; Marcus, MM; Shahid, M; Svensson, TH | 1 |
| Grunnet, M; Grupe, M; Jensen, AA; Paolone, G; Sandager-Nielsen, K; Sarter, M | 1 |
| Bannen, LC; Betageri, R; Chan, DS; DiSalvo, D; Fletcher, K; Harcken, C; Hickey, E; Hill-Drzewi, M; Hopkins, TD; Horan, JC; Kemper, RA; Kuzmich, D; Lemieux, RM; Levin, JI; Linehan, B; Liu, P; Lord, J; Mac, MB; Mao, C; Miller, C; Modis, LK; Ng, S; Patel, M; Patenaude, L; Smith, D; Studwell, D; Terenzzio, D; Wang, Y; Xia, H; Xu, W; Yu, H | 1 |
| Dalley, JW; Isherwood, SN; Pekcec, A; Robbins, TW | 1 |
1 review(s) available for glutamic acid and oxadiazoles
| Article | Year |
|---|---|
The physiology of excitatory amino acids in the vertebrate central nervous system.
Topics: Amino Acids; Animals; Aspartic Acid; Central Nervous System; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Vertebrates | 1987 |
178 other study(ies) available for glutamic acid and oxadiazoles
| Article | Year |
|---|---|
NBQX, an AMPA antagonist, reduces glutamate-mediated brain edema.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Brain; Brain Edema; Glutamates; Glutamic Acid; Hematocrit; Male; Oxadiazoles; Protamines; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Serum Albumin | 1992 |
Properties of non-NMDA excitatory amino acid-activated channels in isolated retinal horizontal cells.
Topics: Animals; Cell Separation; Electric Conductivity; Fishes; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Oxadiazoles; Quisqualic Acid; Retina; Time Factors | 1990 |
RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Codon; Exons; Genomic Library; Glutamates; Glutamic Acid; Glutamine; Ion Channel Gating; Kainic Acid; Liver; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Oligodeoxyribonucleotides; Oxadiazoles; Polymerase Chain Reaction; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA; RNA, Messenger | 1991 |
Autoradiographic characterization and localization of quisqualate binding sites in rat brain using the antagonist [3H]6-cyano-7-nitroquinoxaline-2,3-dione: comparison with (R,S)-[3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Oxadiazoles; Oxazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling.
Topics: Aniline Compounds; Astrocytes; Calcium; Cells, Cultured; Cytoplasm; Fluorescent Dyes; Glutamates; Glutamic Acid; Hippocampus; Intercellular Junctions; Kainic Acid; Oxadiazoles; Periodicity; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Xanthenes | 1990 |
Quisqualate receptor-mediated depression of calcium currents in hippocampal neurons.
Topics: Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Electric Conductivity; Glutamates; Glutamic Acid; GTP-Binding Proteins; Hippocampus; Humans; Membrane Potentials; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Second Messenger Systems; Virulence Factors, Bordetella | 1990 |
Acute- and long-term glutamate-mediated regulation of [Ca++]i in rat hippocampal pyramidal neurons in vitro.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
L-[3H]glutamate labels the metabotropic excitatory amino acid receptor in rodent brain.
Topics: Animals; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Further characterisation of excitatory amino acid receptors coupled to phosphoinositide metabolism in astrocytes.
Topics: Astrocytes; Cells, Cultured; Glutamates; Glutamic Acid; Ibotenic Acid; Neurotransmitter Agents; Oxadiazoles; Oxazoles; Phosphatidylinositols; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Phosphoinositide breakdown in rat hippocampal slices: sensitivity to glutamate induced by in vitro anoxia.
Topics: Animals; Calcium; Glutamates; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Oxadiazoles; Oxygen; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
An electrophysiological study of the action of N-methyl-D-aspartate on excitatory synaptic transmission in the optic tectum of the frog in vitro.
Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Electrophysiology; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rana temporaria; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Synapses; Synaptic Transmission | 1990 |
Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1990 |
Modulation of phosphoinositide metabolism in rat brain slices by excitatory amino acids, arachidonic acid, and GABA.
Topics: Amino Acids; Animals; Arachidonic Acid; Arachidonic Acids; Brain; Calcium; Carbachol; Egtazic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydrolysis; Kinetics; Male; Manganese; Norepinephrine; Oxadiazoles; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Quisqualic Acid; Rats; Rats, Inbred Strains; Verapamil | 1990 |
Excitatory amino acid-induced formation of inositol phosphates in guinea-pig cerebral cortical slices: involvement of ionotropic or metabotropic receptors?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium Chloride; Carbachol; Cerebral Cortex; Cycloleucine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Oxadiazoles; Oxazoles; Potassium Chloride; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Cerebellar Cortex; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Olivopontocerebellar Atrophies; Oxadiazoles; Receptors, AMPA; Receptors, Neurotransmitter; Reference Values; Spinocerebellar Degenerations; Tritium | 1990 |
A comparison of the effect of calcium channel ligands and GABAB agonists and antagonists on transmitter release and somatic calcium channel currents in cultured neurons.
Topics: Animals; Baclofen; Calcium Channel Agonists; Calcium Channels; Cells, Cultured; Cerebellum; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Glutamates; Glutamic Acid; Neurons; Neurotransmitter Agents; Nicotinic Acids; Oxadiazoles; Stereoisomerism; Virulence Factors, Bordetella | 1990 |
TI-233 as a glutamate channel blocker at the crayfish neuromuscular junction.
Topics: Animals; Arginine; Astacoidea; Evoked Potentials; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1985 |
Evidence that excitatory amino acids not only activate the receptor channel complex but also lead to use-dependent block.
Topics: Amino Acids; Animals; Aspartic Acid; Chick Embryo; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Neurotransmitter; Spinal Cord | 1986 |
Phencyclidine selectively blocks a spinal action of N-methyl-D-aspartate in mice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Dipeptides; Drug Interactions; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Glutamates; Glutamic Acid; Injections, Spinal; Kainic Acid; Male; Mice; N-Methylaspartate; Norepinephrine; Oxadiazoles; Phencyclidine; Quisqualic Acid; Spinal Cord; Substance P; Tetrazoles; Valine | 1986 |
Evidence for a magnesium-insensitive membrane resistance increase during NMDA-induced depolarizations in rat neocortical neurons in vitro.
Topics: Animals; Aspartic Acid; Cell Membrane; Electric Conductivity; Frontal Lobe; Glutamates; Glutamic Acid; Ion Channels; Magnesium; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1987 |
A study of amino acid-activated currents recorded from frog motoneurones in vitro.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anterior Horn Cells; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neural Conduction; Oxadiazoles; Quisqualic Acid; Rana temporaria; Valine | 1987 |
Rapid activation and desensitization by glutamate of excitatory, cation-selective channels in locust muscle.
Topics: Animals; Aspartic Acid; Cations; Glutamates; Glutamic Acid; Grasshoppers; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscles; Oxadiazoles; Quisqualic Acid | 1988 |
L-glutamate binding site on N18-RE-105 neuroblastoma hybrid cells is not coupled to an ion channel.
Topics: Aminobutyrates; Animals; Binding, Competitive; Calcium; Chlorides; Cystine; Electric Conductivity; Fluorescent Antibody Technique; Glutamates; Glutamic Acid; Hybrid Cells; Intermediate Filament Proteins; Ion Channels; Mice; Neuroblastoma; Neurofilament Proteins; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium; Tumor Cells, Cultured | 1988 |
Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter | 1988 |
Enhancement of desensitization of quisqualate-type glutamate receptor by the dissociative anaesthetic ketamine.
Topics: Action Potentials; Animals; Concanavalin A; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Grasshoppers; Ion Channels; Ketamine; Kinetics; Membrane Potentials; Muscle Contraction; Muscles; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Multiple conductance channels in type-2 cerebellar astrocytes activated by excitatory amino acids.
Topics: Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Cerebellum; Convulsants; Electric Conductivity; Evoked Potentials; Glutamates; Glutamic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Synaptic Transmission | 1989 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
Expression of excitatory amino acid receptors by cerebellar cells of the type-2 astrocyte cell lineage.
Topics: Animals; Aspartic Acid; Astrocytes; Autoradiography; Cell Line; Cerebellum; Drug Interactions; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Separation of quisqualate- and kainate-selective glutamate receptors in cultured neurons from the rat superior colliculus.
Topics: Animals; Cells, Cultured; Electrolytes; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Kainic Acid; Neurons; Osmolar Concentration; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Superior Colliculi; Time Factors | 1989 |
L-[3H]glutamate binding to a membrane preparation from crayfish muscle.
Topics: Animals; Aspartic Acid; Astacoidea; Binding, Competitive; Calcium; Cell Membrane; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Muscles; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Stereoisomerism | 1989 |
Modulation of dendritic release of dopamine by N-methyl-D-aspartate receptors in rat substantia nigra.
Topics: Amino Acids; Animals; Aspartic Acid; Calcium; Dendrites; Dopamine; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Kinetics; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substantia Nigra; Tetrodotoxin | 1989 |
A voltage-clamp study of isolated stingray horizontal cell non-NMDA excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Separation; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Fishes; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Osmolar Concentration; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1989 |
Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Dopamine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Oxadiazoles; Phenazocine; Potassium; Putamen; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Pharmacological characterization of voltage-clamped catfish rod horizontal cell responses to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Catfishes; Convulsants; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid | 1989 |
L-glutamate binding sites of normal and atrophic human cerebellum.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Binding, Competitive; Cerebellum; Child; Child, Preschool; Glutamates; Glutamic Acid; Humans; Infant; Infant, Newborn; Kinetics; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Activation of excitatory amino acid receptors reduces thymidine incorporation and cell proliferation rate in primary cultures of astrocytes.
Topics: Animals; Astrocytes; Brain; Cell Division; Cells, Cultured; Glutamates; Glutamic Acid; Ibotenic Acid; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Thymidine | 1989 |
Solubilization of quisqualate-sensitive [3H]glutamate binding activity from rat retina.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Octoxynol; Oxadiazoles; Polyethylene Glycols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Solubility | 1989 |
Contamination of commercially available quisqualic acid by glutamate-like and aspartate-like substances.
Topics: Aspartic Acid; Chromatography, High Pressure Liquid; Drug Contamination; Glutamates; Glutamic Acid; Oxadiazoles; Quisqualic Acid | 1989 |
K+ differentially affects the excitatory amino acids- and carbachol-elicited inositol phosphate formation in rat brain synaptoneurosomes.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Carbachol; Frontal Lobe; Glutamates; Glutamic Acid; Inositol Phosphates; N-Methylaspartate; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Sugar Phosphates; Synaptosomes | 1989 |
Evidence that glutamate mediates axon-to-Schwann cell signaling in the squid.
Topics: Action Potentials; Animals; Aspartic Acid; Axons; Cell Communication; Convulsants; Decapodiformes; Electric Stimulation; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Oxadiazoles; Quisqualic Acid; Schwann Cells | 1989 |
Two distinct quisqualate receptors regulate Ca2+ homeostasis in hippocampal neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Calcium Channels; Glutamates; Glutamic Acid; Hippocampus; Homeostasis; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Oxadiazoles; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter; Synapses | 1989 |
Excitatory amino acids enhance dissociation of zinc from soluble protein in cytosol of rat hippocampus.
Topics: Amino Acids; Animals; Aspartic Acid; Cytosol; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Nerve Tissue Proteins; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Zinc | 1989 |
Characterization of deep dorsal horn neurones in the rat spinal cord in vitro: synaptic and excitatory amino acid induced excitations.
Topics: Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Synapses | 1989 |
Activation of polyphosphoinositide metabolism as a signal-transducing system coupled to excitatory amino acid receptors in astroglial cells.
Topics: Animals; Astrocytes; Calcium; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Glutamates; Glutamic Acid; Inositol Phosphates; Kainic Acid; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Second Messenger Systems; Sugar Phosphates | 1989 |
Transient increase of NMDA-binding sites in human hippocampus during development.
Topics: Adult; Aging; Aspartic Acid; Fetus; Glutamates; Glutamic Acid; Hippocampus; Humans; Infant; Infant, Newborn; Middle Aged; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
L-[35S]cysteic acid selectively detects chloride-dependent L-glutamate transporters in synaptic membrane.
Topics: Amino Acids, Sulfur; Animals; Calcium; Carrier Proteins; Cerebral Cortex; Chlorides; Cysteic Acid; Glutamates; Glutamic Acid; Male; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptosomes | 1989 |
Selective effects of serotonin upon excitatory amino acid-induced depolarizations of Purkinje cells in cerebellar slices from young rats.
Topics: Action Potentials; Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Serotonin | 1989 |
Developmental changes in the chemosensitivity of rat brain synaptoneurosomes to excitatory amino acids, estimated by inositol phosphate formation.
Topics: Aging; Animals; Aspartic Acid; Carbachol; Female; Frontal Lobe; Glutamates; Glutamic Acid; Inositol Phosphates; Male; N-Methylaspartate; Norepinephrine; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Synaptosomes | 1989 |
Measurement of amino acid release from cultured cerebellar granule cells by an improved high performance liquid chromatography procedure.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Taurine | 1989 |
Extracellular taurine increase in rat hippocampus evoked by specific glutamate receptor activation is related to the excitatory potency of glutamate agonists.
Topics: Action Potentials; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kainic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Inhibition of rat brain glutamate receptors by philanthotoxin.
Topics: Animals; Aspartic Acid; Bee Venoms; Brain; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Wasp Venoms; Xenopus | 1989 |
Stimulation of inositol phospholipid hydrolysis by excitatory amino acids is enhanced in brain slices from vulnerable regions after transient global ischemia.
Topics: Animals; Brain; Carbachol; Cerebral Cortex; Corpus Striatum; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Ischemic Attack, Transient; Kinetics; Male; Norepinephrine; Organ Specificity; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Reperfusion | 1989 |
Different classes of glutamate receptors mediate distinct behaviors in a single brainstem nucleus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Avoidance Learning; Brain Stem; Electric Fish; Electric Organ; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; N-Methylaspartate; Oxadiazoles; Pipecolic Acids; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.
Topics: Animals; Arginine; Aspartic Acid; Cerebellum; Citrulline; Cyclic GMP; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Glutamate receptor-linked changes in membrane potential and intracellular Ca2+ in primary rat astrocytes.
Topics: Animals; Astrocytes; Brain; Calcium; Cells, Cultured; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1989 |
Selective inhibition of excitatory amino acids by divalent cations. A novel means for distinguishing N-methyl-D-aspartic acid-, kainate- and quisqualate-mediated actions in the mouse spinal cord.
Topics: Animals; Aspartic Acid; Behavior, Animal; Calcium; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; Male; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Spinal Cord; Zinc | 1989 |
Early warning for LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Synapses; Time Factors | 1989 |
Intracellular calcium mobilization triggered by a glutamate receptor in rat cultured hippocampal cells.
Topics: Animals; Animals, Newborn; Calcium; Cells, Cultured; Glutamates; Glutamic Acid; Hippocampus; Intracellular Membranes; Oxadiazoles; Pertussis Toxin; Potassium; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Virulence Factors, Bordetella | 1989 |
Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress.
Topics: Animals; Biological Transport; Calcium; Cell Survival; Cystine; Depression, Chemical; Glutamates; Glutamic Acid; Glutathione; Hippocampus; Hybridomas; Mice; Neurons; Oxadiazoles; Oxidation-Reduction; Peroxides; Quisqualic Acid; Rats | 1989 |
Some properties of ionic channels activated by excitatory amino acids in hippocampal neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Electric Conductivity; Electric Stimulation; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Homocysteine; In Vitro Techniques; Ion Channels; Manganese; Oxadiazoles; Quisqualic Acid | 1985 |
The effects of potassium channel blocking agents on the responses of in vitro frog motoneurones to glutamate and other excitatory amino acids: an intracellular study.
Topics: Amino Acids; Animals; Aspartic Acid; Cell Membrane; Glutamates; Glutamic Acid; Homocysteine; In Vitro Techniques; Ion Channels; N-Methylaspartate; Oxadiazoles; Potassium; Quisqualic Acid; Rana temporaria; Spinal Cord | 1985 |
Excitatory amino acid-induced responses of frog motoneurones bathed in low Na+ media: an intracellular study.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Ion Channels; Membrane Potentials; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana temporaria; Sodium; Spinal Cord | 1985 |
Quantitative studies on some antagonists of N-methyl D-aspartate in slices of rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; Corpus Callosum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Ketamine; Male; Muscimol; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1985 |
Quisqualate and L-glutamate inhibit retinal horizontal-cell responses to kainate.
Topics: Animals; Drug Interactions; Electrophysiology; Glutamates; Glutamic Acid; Goldfish; In Vitro Techniques; Kainic Acid; Oxadiazoles; Pyrrolidines; Quisqualic Acid; Retina | 1985 |
Developmental changes in the glutamate receptor at the insect neuromuscular synapse.
Topics: Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Larva; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission; Tenebrio | 1985 |
The excitation of frog motoneurones in vitro by the glutamate analogue, DI-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), and the effect of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Membrane Potentials; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Rana temporaria; Receptors, AMPA; Receptors, Drug; Spinal Cord; Synapses; Synaptic Transmission; Valine | 1985 |
Excitatory effects of L-glutamate and some analogs on isolated horizontal cells from the catfish retina.
Topics: Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Retina | 1985 |
Anticonvulsant action of beta-kainic acid in mice. Is beta-kainic acid an N-methyl-D-aspartate antagonist?
Topics: Animals; Anticonvulsants; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Homocysteine; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Pyrrolidines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid; Seizures; Stereoisomerism | 1985 |
Blocking action of pentobarbital on receptors for excitatory amino acids in the guinea pig hippocampus.
Topics: Amino Acids; Animals; Convulsants; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Kainic Acid; Neurons; Oxadiazoles; Pentobarbital; Quisqualic Acid; Receptors, Neurotransmitter; Synapses | 1985 |
Effects of bath-applied excitatory amino acids and their analogs on spinal interneurons of the lamprey.
Topics: Amino Acids; Animals; Aspartic Acid; Fishes; Glutamates; Glutamic Acid; Glycine; Homocysteine; In Vitro Techniques; Interneurons; Kainic Acid; Lampreys; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Spinal Cord | 1985 |
Inhibitors of high-affinity uptake augment depolarizations of hippocampal neurons induced by glutamate, kainate and related compounds.
Topics: Animals; Aspartic Acid; Drug Synergism; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Homocysteine; In Vitro Techniques; Kainic Acid; Oxadiazoles; Quisqualic Acid; Synaptic Transmission | 1985 |
The characterization of the specific binding of [3H]-N-acetylaspartylglutamate to rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; Calcium; Dipeptides; Glutamates; Glutamic Acid; Guanine Nucleotides; Ibotenic Acid; Kinetics; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Serine; Sodium; Synaptosomes; Tissue Distribution | 1985 |
Peptides derived from kainic acid as antagonists of N-methyl-D-aspartate-induced neuroexcitation in rat brain.
Topics: Animals; Aspartic Acid; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1985 |
Excitatory and inhibitory responses of Purkinje cells, in the rat cerebellum in vivo, induced by excitatory amino acids.
Topics: Amino Acids; Animals; Aspartic Acid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Coupling of inositol phospholipid metabolism with excitatory amino acid recognition sites in rat hippocampus.
Topics: Animals; Aspartic Acid; Calcium; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Male; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord | 1986 |
A dipeptide derived from kainic and L-glutamic acids: a selective antagonist of amino acid induced neuroexcitation with anticonvulsant properties.
Topics: Animals; Aspartic Acid; Cell Membrane Permeability; Corpus Striatum; Dipeptides; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Oxadiazoles; Picrotoxin; Quisqualic Acid; Rats; Seizures; Sodium | 1985 |
Evidence for L-glutamate as a transmitter substance of motoneurons innervating squid chromatophore muscles.
Topics: Animals; Chromatophores; Decapodiformes; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Motor Neurons; Muscle Contraction; Muscles; Neuromuscular Depolarizing Agents; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid | 1985 |
Action of excitatory amino acids and their antagonists on hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Excitatory Amino Acid Antagonists; Glutamic Acid; Guinea Pigs; Hippocampus; Iontophoresis; Manganese; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Tetrodotoxin; Valine | 1985 |
Induction of glutamate binding sites in hippocampal membranes by transient exposure to high concentrations of glutamate or glutamate analogs.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Aminobutyrates; Animals; Aspartic Acid; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Saponins; Sodium; Valine | 1986 |
Excitatory amino acid receptors in hippocampal neurons: kainate fails to desensitize them.
Topics: Animals; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1986 |
Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors.
Topics: Age Factors; Aminobutyrates; Animals; Aspartic Acid; Drug Interactions; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Norepinephrine; Oxadiazoles; Oxazoles; Phosphatidylinositols; Phosphoserine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Amino Acid; Receptors, Cell Surface | 1986 |
Pharmacologically distinct glutamate receptors on cerebellar granule cells.
Topics: 2-Aminoadipic Acid; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1986 |
Effects of D-aspartate on excitatory amino acid-induced release of [3H]GABA from goldfish retina.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Goldfish; Kainic Acid; Oxadiazoles; Quisqualic Acid; Retina; Tritium | 1986 |
A comparative study on the elicitability of vocalization by electrical brain stimulation, glutamate, aspartate and quisqualate in the squirrel monkey.
Topics: Animals; Aspartic Acid; Brain Mapping; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Reaction Time; Saimiri; Vocalization, Animal | 1986 |
Receptors for excitatory amino acids on neurons in rat pyriform cortex.
Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Limbic System; N-Methylaspartate; Olfactory Pathways; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Neurotransmitter; Synaptic Transmission | 1986 |
Chemoresponsiveness of intracellular nuclei neurones to L-aspartate, L-glutamate and related derivatives in rat cerebellar slices maintained in vitro.
Topics: Animals; Aspartic Acid; Cerebellar Nuclei; Convulsants; Glutamates; Glutamic Acid; In Vitro Techniques; Injections; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Comparative actions of quisqualate and N-methyl-D-aspartate, excitatory amino acid agonists, on guinea-pig cochlear potentials.
Topics: Action Potentials; Animals; Aspartic Acid; Cochlea; Dose-Response Relationship, Drug; Evoked Potentials; Glutamates; Glutamic Acid; Guinea Pigs; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Vestibulocochlear Nerve | 1986 |
Synaptosomal transport of radiolabel from N-acetyl-aspartyl-[3H]glutamate suggests a mechanism of inactivation of an excitatory neuropeptide.
Topics: Amino Acids; Animals; Biological Transport; Brain; Dipeptides; Glutamates; Glutamic Acid; Kinetics; Male; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Sodium; Synaptosomes; Tritium | 1986 |
Characterization of L-glutamate binding sites in rat spinal cord synaptic membranes: evidence for multiple chloride ion-dependent sites.
Topics: Aminobutyrates; Animals; Anions; Brain; Calcium; Cations; Chlorides; Diencephalon; Glutamates; Glutamic Acid; Kinetics; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium; Spinal Cord; Synaptic Membranes; Telencephalon | 1986 |
In vitro release and electrophysiological effects in situ of homocysteic acid, an endogenous N-methyl-(D)-aspartic acid agonist, in the mammalian striatum.
Topics: Animals; Aspartic Acid; Calcium; Cats; Caudate Nucleus; Chromatography, High Pressure Liquid; Corpus Striatum; Drug Synergism; Electric Stimulation; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Homocysteine; Iontophoresis; Oxadiazoles; Potassium; Quisqualic Acid; Rana temporaria; Rats; Veratrine | 1986 |
Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity.
Topics: Animals; Aspartic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Kainic Acid; Mice; N-Methylaspartate; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; Neurons; Oxadiazoles; Pyridines; Quinolinic Acid; Quinolinic Acids; Quisqualic Acid | 1986 |
Binding sites for [3H]glutamate and [3H]aspartate in human cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aspartic Acid; Binding Sites; Calcium Chloride; Cerebellum; Dicarboxylic Acids; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Oxadiazoles; Quisqualic Acid | 1986 |
Chloride-dependent binding sites for L-[3H]glutamate on dendrodendritic synaptosomal membranes of rat olfactory bulb.
Topics: Aminobutyrates; Animals; Chlorides; Dendrites; Glutamates; Glutamic Acid; Male; Olfactory Bulb; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Membranes | 1986 |
Localization of [3H]glutamate binding sites in rat adrenal medulla.
Topics: Acetates; Acetic Acid; Adrenal Medulla; Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Cerebral Cortex; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Organ Specificity; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1986 |
Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Drug Synergism; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; Kainic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Sugar Phosphates; Valine; Veratridine | 1987 |
Specific binding of L-[3H]-glutamic acid to rat substantia nigra synaptic membranes.
Topics: 2-Aminoadipic Acid; Aminobutyrates; Animals; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Kinetics; Male; Oxadiazoles; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Substantia Nigra; Synaptic Membranes | 1986 |
Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Cerebellar Cortex; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Reaction Time; Valine | 1987 |
Spider toxin blocks excitatory amino acid responses in isolated hippocampal pyramidal neurons.
Topics: Animals; Arthropod Venoms; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurotoxins; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spider Venoms; Time Factors | 1987 |
Formation and utilization of the active sulfate donor [35S]3'-phosphoadenosine 5'-phosphosulfate in brain slices: effects of depolarizing agents.
Topics: Adenine Nucleotides; Animals; Aspartic Acid; Cerebral Cortex; Glutamates; Glutamic Acid; Kinetics; Male; Naphthols; Nitrophenols; Oxadiazoles; Phosphoadenosine Phosphosulfate; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Sulfates; Sulfur Radioisotopes; Veratridine; Veratrine | 1987 |
Characterization of quisqualate recognition sites in rat brain tissue using DL-[3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) and a filtration assay.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chemical Phenomena; Chemistry; Filtration; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Oxadiazoles; Oxazoles; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Thiocyanates | 1987 |
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Aminocaproates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Norleucine; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1987 |
Voltage-dependency of the responses of cerebellar Purkinje cells to excitatory amino acids.
Topics: Action Potentials; Animals; Aspartic Acid; Cadmium; Glutamates; Glutamic Acid; Membrane Potentials; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Rats, Inbred Strains; Tetrodotoxin | 1987 |
Glutamate-induced ionic currents in cultured neurons from the rat superior colliculus.
Topics: Animals; Aspartic Acid; Calcium; Cells, Cultured; Glutamates; Glutamic Acid; Magnesium; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Superior Colliculi | 1987 |
Glutamate receptor subtypes in cultured cerebellar neurons: modulation of glutamate and gamma-aminobutyric acid release.
Topics: Animals; Aspartic Acid; Calcium; Cations; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Kinetics; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium | 1987 |
Autoradiographic localization of cerebellar excitatory amino acid binding sites in the mouse.
Topics: Animals; Aspartic Acid; Autoradiography; Binding Sites; Cerebellum; Glutamates; Glutamic Acid; Kainic Acid; Mice; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Colchicine; Corpus Striatum; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Isomerism; Kainic Acid; Mice; N-Methylaspartate; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Valine | 1988 |
Quisqualate-sensitive, chloride-dependent transport of glutamate into rat brain synaptosomes.
Topics: Aging; Animals; Anions; Brain; Corpus Striatum; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Male; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Sodium Chloride; Synaptosomes | 1987 |
Differential effects of serotonin on the spontaneous discharge and on the excitatory amino acid-induced responses of deep cerebellar nuclei neurons in rat cerebellar slices.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Calcium; Cerebellar Nuclei; Drug Interactions; Glutamates; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Serotonin | 1987 |
Excitatory amino acid-evoked membrane currents and excitatory synaptic transmission in lamprey reticulospinal neurons.
Topics: Amino Acids; Animals; Aspartic Acid; Brain Stem; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Lampreys; N-Methylaspartate; Neurons; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Spinal Cord; Synapses; Synaptic Transmission | 1988 |
GABA release from Xenopus retina does not correlate with horizontal cell membrane potential.
Topics: Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; Oxadiazoles; Potassium; Quisqualic Acid; Retina; Xenopus laevis | 1988 |
Characterisation of Na+-independent L-[3H]glutamate binding sites in human temporal cortex.
Topics: 2-Amino-5-phosphonovalerate; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Cell Membrane; Chlorides; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Temporal Lobe | 1988 |
The modulation of excitatory amino acid responses by serotonin in the cat neocortex in vitro.
Topics: Animals; Aspartic Acid; Cats; Cerebral Cortex; Cinanserin; Electric Stimulation; Evoked Potentials; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Methysergide; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Serotonin; Tetraethylammonium Compounds; Tetrodotoxin | 1987 |
Evidence of N-methyl-D-aspartate receptor-mediated modulation of the aortic baroreceptor reflex in the rat nucleus tractus solitarii.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aorta; Blood Pressure; Glutamates; Glutamic Acid; Heart Rate; Kainic Acid; Male; Medulla Oblongata; Oxadiazoles; Pressoreceptors; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Properties of quisqualate-sensitive L-[3H]glutamate binding sites in rat brain as determined by quantitative autoradiography.
Topics: Animals; Autoradiography; Binding Sites; Brain; Calcium; Chlorides; Glutamates; Glutamic Acid; Male; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1988 |
alpha-[3H]Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding to rat striatal membranes: effects of selective brain lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Denervation; Dopamine; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Ibotenic Acid; Membranes; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1988 |
L-glutamate-induced depolarization in solitary photoreceptors: a process that may contribute to the interaction between photoreceptors in situ.
Topics: Animals; Aspartic Acid; Axons; Dose-Response Relationship, Drug; Electric Conductivity; Glutamates; Glutamic Acid; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid; Sodium; Turtles | 1988 |
Phorbol esters attenuate glutamate-stimulated inositol phospholipid hydrolysis in neuronal cultures.
Topics: Animals; Aspartic Acid; Carbachol; Cerebellum; Diglycerides; Glutamates; Glutamic Acid; Hydrolysis; Inositol Phosphates; N-Methylaspartate; Neurons; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Sphingosine; Tetradecanoylphorbol Acetate | 1988 |
An intracellular analysis of amino acid induced excitations of deep dorsal horn neurones in the rat spinal cord slice.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; In Vitro Techniques; Intracellular Membranes; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Spinal Cord; Tetrodotoxin; Valine | 1988 |
Glutamate stimulates somatostatin release from diencephalic neurons in primary culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Cells, Cultured; Diencephalon; Glutamates; Glutamic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Oxadiazoles; Phencyclidine; Potassium; Quisqualic Acid; Rats; Somatostatin; Tetrodotoxin; Valine; Veratridine | 1988 |
The effect of K+ and glutamate receptor agonists on the membrane potential of suspensions of primary cultures of rat astrocytes as measured with a cyanine dye, DiS-C2-(5).
Topics: Animals; Astrocytes; Benzothiazoles; Brain; Carbocyanines; Cells, Cultured; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; Oxadiazoles; Potassium; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Thiazoles; Veratridine | 1988 |
Behavioral classification of excitatory amino acid receptors in mouse spinal cord.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Behavior, Animal; Glutamates; Glutamic Acid; Glutamine; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Spinal Cord; Valine | 1988 |
L-glutamate increases internal free calcium levels in synaptoneurosomes from immature rat brain via quisqualate receptors.
Topics: Animals; Brain; Calcimycin; Calcium; Egtazic Acid; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Isradipine; Male; Osmolar Concentration; Oxadiazoles; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Neurotransmitter; Stereoisomerism; Synaptosomes; Tetrodotoxin; Veratridine | 1988 |
Selective inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by activation of protein kinase C.
Topics: Alkaloids; Amino Acids; Animals; Carbachol; Enzyme Activation; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Ibotenic Acid; Male; Norepinephrine; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Quisqualic Acid; Rats; Rats, Inbred Strains; Staurosporine | 1988 |
Glutamate induces a depolarization of adult rat dorsal root ganglion neurons that is mediated predominantly by NMDA receptors.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Ganglia, Spinal; Glutamates; Glutamic Acid; Glycine; Kainic Acid; Magnesium; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine | 1988 |
Epinephrine and norepinephrine modulate neuronal responses to excitatory amino acids and agonists in frog spinal cord.
Topics: Amino Acids; Animals; Aspartic Acid; Epinephrine; Glutamates; Glutamic Acid; In Vitro Techniques; Isoproterenol; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Norepinephrine; Oxadiazoles; Quisqualic Acid; Rana pipiens; Reference Values; Spinal Cord; Yohimbine | 1987 |
Properties of two classes of rat brain acidic amino acid receptors induced by distinct mRNA populations in Xenopus oocytes.
Topics: Amino Acids; Animals; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Kainic Acid; N-Methylaspartate; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; RNA, Messenger; Xenopus laevis | 1988 |
Characterization of glutamate receptors induced in Xenopus oocytes after injection of rat brain mRNA.
Topics: Animals; Brain; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; Oocytes; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis | 1988 |
Excitatory amino acid receptors in piriform cortex do not show receptor desensitization.
Topics: Animals; Cerebral Cortex; Glutamates; Glutamic Acid; Kainic Acid; Oxadiazoles; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1988 |
Glutamate cytotoxicity in a neuronal cell line is blocked by membrane depolarization.
Topics: Animals; Cell Line; Glutamates; Glutamic Acid; Hybrid Cells; Ibotenic Acid; Membrane Potentials; Neuroblastoma; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Retina | 1988 |
Glutamate opens Na+/K+ channels in cultured astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Glutamates; Glutamic Acid; Kainic Acid; Membrane Potentials; Oxadiazoles; Potassium Channels; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Sodium Channels | 1988 |
Agonist potency determination by patch clamp analysis of single glutamate receptors.
Topics: Animals; Cysteine; Electric Stimulation; Glutamates; Glutamic Acid; Grasshoppers; Ion Channels; Membrane Potentials; Neural Conduction; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Cell Surface; Receptors, Glutamate; Stimulation, Chemical | 1981 |
[Pharmacology of glutamate sensitive synapses (I). Glutamate agonists (author's transl)].
Topics: Action Potentials; Animals; Astacoidea; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Models, Neurological; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Synapses; Synaptic Transmission | 1982 |
Effect of urethane on synaptic and amino acid-induced excitation in isolated spinal cord preparations.
Topics: Animals; Aspartic Acid; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Ranidae; Rats; Spinal Cord; Synapses; Urethane | 1982 |
Selective increase in L-[3H]glutamate binding to a quisqualate-sensitive site on hippocampal synaptic membranes after angular bundle kindling.
Topics: Animals; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Membranes; Tritium | 1982 |
Investigations into the mechanism of excitant amino acid cytotoxicity using a well-characterized glutamatergic system.
Topics: Animals; Aspartic Acid; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Grasshoppers; Kainic Acid; Nerve Degeneration; Neuromuscular Junction; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Receptors, Cell Surface; Receptors, Glutamate; Synaptic Transmission | 1983 |
Chloride and calcium ions separate L-glutamate receptor populations in synaptic membranes.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Calcium; Chlorides; Glutamates; Glutamic Acid; In Vitro Techniques; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Cell Surface; Receptors, Glutamate; Synaptic Membranes | 1983 |
L-[3H]Glutamate binding to hippocampal synaptic membranes: two binding sites discriminated by their differing affinities for quisqualate.
Topics: Animals; Binding, Competitive; Female; Glutamates; Glutamic Acid; Hippocampus; Kinetics; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Cell Surface; Receptors, Drug; Receptors, Glutamate; Synaptic Membranes | 1983 |
Effects of excitatory amino acids on locomotor activity after bilateral microinjection into the rat nucleus accumbens: possible dependence on dopaminergic mechanisms.
Topics: Amino Acids; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Kainic Acid; Male; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Seizures; Septal Nuclei; Synaptic Transmission | 1983 |
Evidence for differential localization of two binding sites for L-[3H]glutamate in rat fascia dentata.
Topics: Animals; Binding Sites; Brain Mapping; Female; Glutamates; Glutamic Acid; Hippocampus; Neural Pathways; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1983 |
Effects of excitatory amino acids on dopamine synthesis in the rat retina.
Topics: Amino Acids; Animals; Aspartic Acid; Dopamine; Glutamates; Glutamic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Retina | 1983 |
Voltage clamp analysis of the effect of excitatory amino acids and derivatives on Purkinje cell dendrites in rat cerebellar slices maintained in vitro.
Topics: Amino Acids; Animals; Aspartic Acid; Culture Techniques; Dendrites; Glutamates; Glutamic Acid; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Synaptic Transmission | 1983 |
Effects of kainic and other amino acids on synaptic excitation in rat hippocampal slices: 1. Extracellular analysis.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Evoked Potentials; Folic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Oxadiazoles; Pyrrolidines; Quisqualic Acid; Rats | 1983 |
The ionic mechanisms associated with the excitatory response of kainate, L-glutamate, quisqualate, ibotenate, AMPA and methyltetrahydrofolate on leech Retzius cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Ganglia; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Leeches; Membrane Potentials; Neurons; Osmolar Concentration; Oxadiazoles; Oxazoles; Pyrrolidines; Quisqualic Acid; Sodium; Tetrahydrofolates | 1984 |
On the sensitivity of H1 horizontal cells of the carp retina to glutamate, aspartate and their agonists.
Topics: Animals; Aspartic Acid; Carps; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Retina | 1984 |
l-Glutamate reduces the affinity of [3H]N-propylnorapomorphine binding sites in striatal membranes.
Topics: Animals; Antiparkinson Agents; Apomorphine; Aspartic Acid; Binding Sites; Cell Membrane; Corpus Striatum; Glutamates; Glutamic Acid; Male; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Spiperone | 1984 |
Glutamate inhibitory action of matrine at the crayfish neuromuscular junction.
Topics: Action Potentials; Alkaloids; Animals; Astacoidea; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Matrines; Muscles; Neuromuscular Junction; Oxadiazoles; Quinolizines; Quisqualic Acid | 1984 |
Effect of excitatory amino acids on Purkinje cell dendrites in cerebellar slices from normal and staggerer mice.
Topics: Amino Acids; Animals; Aspartic Acid; Crosses, Genetic; Dendrites; Glutamates; Glutamic Acid; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Neurologic Mutants; N-Methylaspartate; Oxadiazoles; Purkinje Cells; Quisqualic Acid | 1984 |
Selective and reversible increase in the number of quisqualate-sensitive glutamate binding sites on hippocampal synaptic membranes after angular bundle kindling.
Topics: Animals; Calcium; Glutamates; Glutamic Acid; Hippocampus; Kindling, Neurologic; Male; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptic Transmission | 1984 |
Mixed-agonist action of excitatory amino acids on mouse spinal cord neurones under voltage clamp.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Culture Techniques; Electric Conductivity; Glutamates; Glutamic Acid; Homocysteine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Spinal Cord; Valine | 1984 |
The effect of D-alpha-aminoadipate on excitatory amino acid responses recorded intracellularly from motoneurones of the frog spinal cord.
Topics: 2-Aminoadipic Acid; Amino Acids; Amino Acids, Dicarboxylic; Animals; Anterior Horn Cells; Aspartic Acid; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rana temporaria; Spinal Nerve Roots | 1984 |
Selective association of N-methyl aspartate and quisqualate types of L-glutamate receptor with brain postsynaptic densities.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Chlorides; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Membranes | 1984 |
Arginine-vasopressin enhances the responses of lateral septal neurons in the rat to excitatory amino acids and fimbria-fornix stimuli.
Topics: Amino Acids; Animals; Arginine Vasopressin; Aspartic Acid; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Muscimol; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Synapses | 1984 |
Fast and slow depolarizing potentials induced by short pulses of kainic acid in hippocampal neurons.
Topics: Acetates; Acetic Acid; Animals; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Kainic Acid; Manganese; Membrane Potentials; Oxadiazoles; Pyrrolidines; Quisqualic Acid; Synapses; Synaptic Transmission | 1984 |
Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Glutamic Acid; Male; N-Methylaspartate; Oxadiazoles; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Signal Transduction; Sumatriptan; Synapses; Synaptic Transmission | 1996 |
Both protein kinase G dependent and independent mechanisms are involved in the modulation of glutamate release by nitric oxide in rat hippocampal nerve terminals.
Topics: 4-Aminopyridine; Animals; Calcium; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hippocampus; Nitric Oxide; Nitroprusside; Oxadiazoles; Presynaptic Terminals; Protein Kinases; Quinoxalines; Rats; Sulfhydryl Reagents; Synaptosomes; Thionucleotides | 1999 |
Pharmacological diversity between native human 5-HT1B and 5-HT1D receptors sited on different neurons and involved in different functions.
Topics: Adult; Aged; Binding Sites; Biphenyl Compounds; Cerebral Cortex; Female; Glutamic Acid; Humans; Male; Middle Aged; Neurons; Oxadiazoles; Piperazines; Piperidones; Potassium Chloride; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiro Compounds; Synaptosomes; Tritium | 1999 |
BIIR 561 CL: a novel combined antagonist of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors and voltage-dependent sodium channels with anticonvulsive and neuroprotective properties.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Batrachotoxins; Benzodiazepines; Cell Membrane; Cells, Cultured; Cerebral Cortex; Electroshock; Embryo, Mammalian; Glutamic Acid; In Vitro Techniques; Ischemic Attack, Transient; Male; Mexiletine; Mice; Neurons; Neuroprotective Agents; Oxadiazoles; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sodium Channel Blockers; Sodium Channels; Synaptosomes; Veratridine | 1999 |
Activation of spinal N-methyl-D-aspartate receptors stimulates a nitric oxide/cyclic guanosine 3,5-monophosphate/glutamate release cascade in nociceptive signaling.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanylate Cyclase; Male; Microdialysis; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; Synaptic Transmission | 1999 |
Inhibition of the glutamate-induced K(+) current in identified Onchidium neurons by nitric oxide donors.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Membrane; Cyclic GMP; Enzyme Inhibitors; Ganglia, Invertebrate; Glutamic Acid; Hydrazines; Mollusca; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Potassium Channels; Quinoxalines; Vasodilator Agents | 2000 |
Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: effects on native and recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.
Topics: Animals; Anticonvulsants; Benzodiazepines; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Neuroprotective Agents; Oxadiazoles; Rats; Receptors, AMPA; Recombinant Proteins | 2000 |
Glutamate and NO mediation of the pressor response to 5-HT3 receptor stimulation in the nucleus tractus solitarii.
Topics: Animals; Biguanides; Blood Pressure; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanylate Cyclase; Indazoles; Male; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reflex; Serotonin; Serotonin Receptor Agonists; Solitary Nucleus; Synaptic Transmission | 2002 |
Release of arginine, glutamate and glutamine in the hippocampus of freely moving rats: Involvement of nitric oxide.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Glutamine; Hippocampus; Indazoles; Male; Microdialysis; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Wakefulness | 2005 |
Nitric oxide inhibits mitochondrial movement in forebrain neurons associated with disruption of mitochondrial membrane potential.
Topics: Animals; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Glutamic Acid; Hydrazines; Membrane Potentials; Mitochondria; Movement; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Prosencephalon; Quinoxalines; Rats; Time Factors | 2006 |
Glutamatergic Control of Microvascular Tone by Distinct GABA Neurons in the Cerebellum.
Topics: Animals; Cerebellum; Cerebrovascular Circulation; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Hydrazines; In Vitro Techniques; Male; Microcirculation; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Oxadiazoles; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation | 2006 |
Differential sensitivity of excitatory and inhibitory synaptic transmission to modulation by nitric oxide in rat nucleus tractus solitarii.
Topics: Animals; Animals, Newborn; Diethylamines; Dose-Response Relationship, Drug; Electrochemistry; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glutamic Acid; Guanylate Cyclase; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neural Inhibition; Neurons; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Patch-Clamp Techniques; Presynaptic Terminals; Pyrazoles; Pyridines; Quinoxalines; Rats; Rats, Wistar; Solitary Nucleus; Synaptic Transmission; Time Factors | 2007 |
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Astrocytes; beta-Alanine; Calcium Signaling; Cell Movement; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Dose-Response Relationship, Drug; Embryo, Mammalian; Fingolimod Hydrochloride; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Immunosuppressive Agents; Inositol Phosphates; Organ Culture Techniques; Oxadiazoles; Propylene Glycols; Rats; Receptors, Lysosphingolipid; Sphingosine; Thiophenes | 2007 |
Interaction between glutamatergic and nitrergic mechanisms mediating cardiovascular responses to L-glutamate injection in the diagonal band of Broca in anesthetized rats.
Topics: Anesthesia; Animals; Arginine; Benzoates; Blood Pressure; Diagonal Band of Broca; Dose-Response Relationship, Drug; Glutamic Acid; Heart Rate; Imidazoles; Isoquinolines; Male; Microinjections; Nitrergic Neurons; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate | 2007 |
Pre-conditioning induced by carbon monoxide provides neuronal protection against apoptosis.
Topics: Animals; Animals, Newborn; Apoptosis; Carbon Monoxide; Cells, Cultured; Cerebellum; Decanoic Acids; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Hydroxy Acids; Metalloporphyrins; Mice; Neurons; NG-Nitroarginine Methyl Ester; Oxadiazoles; Oxidative Stress; Quinoxalines; Reactive Oxygen Species; tert-Butylhydroperoxide; Time Factors | 2008 |
Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor.
Topics: Allosteric Regulation; Animals; Benzamides; Calcium Compounds; Calcium Signaling; Cerebral Cortex; CHO Cells; Cricetinae; Cricetulus; Glutamic Acid; Hydrazines; Oxadiazoles; Oxides; Phthalimides; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2009 |
4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues.
Topics: Amino Acids, Acidic; Animals; Brain; Cell Line; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; In Vitro Techniques; Male; Oocytes; Oxadiazoles; Patch-Clamp Techniques; Potentiometry; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis | 2010 |
Cardiovascular responses to L-glutamate microinjection into the hypothalamic paraventricular nucleus are mediated by a local nitric oxide-guanylate cyclase mechanism.
Topics: Animals; Benzoates; Blood Pressure; Cardiovascular System; Drug Interactions; Glutamic Acid; Guanylate Cyclase; Heart Rate; Imidazoles; Male; Microinjections; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Paraventricular Hypothalamic Nucleus; Quinoxalines; Rats; Rats, Wistar; Time Factors; Wakefulness | 2010 |
Structure-activity study on a series of α-glutamic acid scaffold based compounds as new ADAMTS inhibitors.
Topics: ADAM Proteins; ADAMTS4 Protein; ADAMTS5 Protein; Binding Sites; Computer Simulation; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Oxadiazoles; Procollagen N-Endopeptidase; Protease Inhibitors; Structure-Activity Relationship | 2011 |
Differential effects of AMPA receptor potentiators and glycine reuptake inhibitors on antipsychotic efficacy and prefrontal glutamatergic transmission.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Catalepsy; Drug Synergism; Glutamic Acid; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Membrane Potentials; Olanzapine; Oxadiazoles; Piperidines; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, AMPA; Risperidone; Synaptic Transmission; Tetrahydronaphthalenes | 2012 |
Selective potentiation of (α4)3(β2)2 nicotinic acetylcholine receptors augments amplitudes of prefrontal acetylcholine- and nicotine-evoked glutamatergic transients in rats.
Topics: Acetylcholine; Allosteric Regulation; Animals; Glutamic Acid; HEK293 Cells; Humans; Microelectrodes; Nicotine; Nicotinic Agonists; Oxadiazoles; Prefrontal Cortex; Pyridines; Rats; Receptors, Nicotinic | 2013 |
Late-stage optimization of a tercyclic class of S1P3-sparing, S1P1 receptor agonists.
Topics: Animals; Brain; Glutamic Acid; Hep G2 Cells; Humans; Hydrogen Bonding; Kinetics; Oxadiazoles; Rats; Receptors, Lysosphingolipid; Solubility; Structure-Activity Relationship; Thiadiazoles | 2016 |
Bidirectional variation in glutamate efflux in the medial prefrontal cortex induced by selective positive and negative allosteric mGluR5 modulators.
Topics: Allosteric Regulation; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Imidazoles; Male; Oxadiazoles; Piperidines; Prefrontal Cortex; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate | 2018 |