glutamic acid and melatonin

glutamic acid has been researched along with melatonin in 87 studies

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.30)18.7374
1990's25 (28.74)18.2507
2000's25 (28.74)29.6817
2010's28 (32.18)24.3611
2020's7 (8.05)2.80

Authors

AuthorsStudies
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Kus, L; McNulty, JA; Ottersen, OP1
Mitchell, CK; Redburn, DA1
Redburn, DA1
Exposito, I; Mora, F; Oaknin, S1
Giusti, P; Gusella, M; Lipartiti, M; Manev, H; Milani, D; Vicini, S; Zhu, W1
Handa, RJ; Kus, L; McNulty, JA1
Chen, LD; Manchester, LC; Poeggeler, B; Reiter, RJ; Tan, DX1
Exposito, I; Mora, F; Oaknin, S; Zisapel, N1
Behl, C; Lezoualc'h, F; Skutella, T; Widmann, M1
Furuichi, T; Kozaki, S; Michibata, H; Mikoshiba, K; Morita, M; Moriyama, Y; Takahashi, M; Yamada, H; Yamamoto, A; Yodozawa, S1
Floreani, M; Giusti, P; Gusella, M; Lipartiti, M; Manev, H1
Giusti, P; Manev, H; Uz, T1
Futai, M; Hayashi, M; Ishio, S; Moriyama, Y; Nishi, T; Yamada, H; Yamaguchi, A; Yamamoto, A; Yatsushiro, S1
Behl, C; Lezoualc'h, F; Sparapani, M1
Acuña-Castroviejo, D; Camacho, E; Escames, G; Espinosa, A; Gallo, MA; Gómez, I; León, J; Vives, F1
Acuña-Castroviejo, D; Camacho, E; Crespo, E; Escames, G; Espinosa, A; Gallo, MA; León, J; Vives, F1
Koizumi, S; Moriyama, Y; Ogura, A; Yamada, H; Yamaguchi, A1
Moriyama, Y; Yamada, H1
Hayashi, M; Ishio, S; Moriyama, Y; Noumi, T; Yamada, H; Yamaguchi, A; Yatsushiro, S1
Hastings, MH; McNulty, S; Schurov, IL; Sloper, PJ1
Dehghani, F; Duffield, GE; Hastings, MH; Kopp, MD; Korf, HW; Stehle, JH; von Gall, C1
Korf, HW; Maronde, E; Molina, CA; Pfeffer, M; Stehle, JH1
Haga, M; Hayashi, M; Moriyama, Y; Yamamoto, A; Yatsushiro, S1
Hayashi, M; Ishio, S; Moriyama, Y; Yamada, H; Yamamoto, A; Yatsushiro, S1
Craft, CM; Ishio, S; Moriyama, Y; Yamada, H1
Moriyama, Y1
Castañeda, TR; del Arco, A; Galindo, A; Marquez de Prado, B; Mora, F; Reiter, RJ; Segovia, G1
Bulucu, D; Düzenli, S; Gepdiremen, A; Hacimüftüoglu, A; Süleyman, H1
Gong, YS; Zhang, JT; Zhang, QZ1
Acuña-Castroviejo, D; Escames, G; García, J; Khaldy, H; León, J; Macías, M; Martín, M; Vives, F1
Gao, HX; Zhang, LX1
Gu, J; Li, XJ; Sun, FY1
Burkhardt, S; Hardeland, R; Huo, YS; Kohen, R; Manchester, LC; Mayo, JC; Reiter, RJ; Sainz, RM; Shohami, E; Tan, DX1
Antolín, I; Herrera, F; Martín, V; Mayo, JC; Rodriguez, C; Sainz, RM1
Markus, RP; Reno, LA; Santos, JM; Zago, W1
Van Gelder, RN1
De Mello, FG; Ferreira, ST; Louzada, PR; Paula-Lima, AC1
Buijs, RM; Kalsbeek, A; Perreau-Lenz, S; Pévet, P1
Besson, MT; Birman, S; Iché, M; Rival, T; Soustelle, L; Strambi, C1
Chianelli, M; Goldin, AP; Minces, L; Rosenstein, RE; Sáenz, DA; Sarmiento, MI1
Antolín, I; Fernández-Marí, F; García-Santos, G; Herrera, F; Martín, V; Rodriguez, C; Rodriguez-Blanco, J1
de Zavalía, N; Keller Sarmiento, MI; Marcos, HA; Moreno, MC; Rosenstein, RE; Sande, P1
Huang, H; Lee, SC; Yang, XL1
Buijs, RM; Kalsbeek, A; Perreau-Lenz, S2
Dagci, T; Peker, G; Taskiran, D; Yilmaz, O1
Bach, A; Bähr, M; Bartels, C; Bohn, M; Dietrich, J; Ehrenreich, H; Hardeland, R; Hüther, G; Mertens, N; Nave, KA; Poeggeler, B; Pölking, E; Rohde, G; Schneider, A; Sirén, AL; Sperling, S; Weishaupt, JH1
Antolín, I; García-Santos, G; Herrera, F; Martin, V; Rodriguez, C; Rodriguez-Blanco, J1
Banik, NL; Belagodu, A; Das, A; Ray, SK; Reiter, RJ1
Kennaway, DJ; Varcoe, TJ1
Hille, B; Kim, MH; Koh, DS; Moriyama, Y; Muroyama, A; Uehara, S1
Allen, GC; McMahon, DG; Ruan, GX; Yamazaki, S1
Kaur, C; Ling, EA; Lu, J; Sivakumar, V1
Banik, NL; Das, A; McDowell, M; Pava, MJ; Ray, SK; Reiter, RJ; Smith, JA; Varma, AK; Woodward, JJ1
Carpenter, LL; Philip, NS; Price, LH; Tyrka, AR1
Belforte, NA; Chianelli, MS; de Zavalía, N; Keller Sarmiento, MI; Moreno, MC; Rosenstein, RE; Sande, PH1
Bonanno, G; Bonifacino, T; Gabriel-Gracia, C; Grilli, M; Mallei, A; Milanese, M; Mocaer, E; Musazzi, L; Popoli, M; Racagni, G; Tardito, D1
Lauro Castrucci, AM; Lima, LH; Santos, KP1
Kaur, C; Ling, EA; Viswanathan, S1
Koh, PO1
Barboni, L; Graham, D; Liao, Z; Nzowa, LK; Tapondjou, LA; Teponno, RB; Verotta, L; Zink, MC1
Mykheĭtseva, IM1
Afeche, SC; Atherino, VF; Cipolla-Neto, J; do Amaral, FG; Lima, Lde S; Martins de Lima, T; Moutinho, AA; Peres, R; Scavone, C; Torrão, Ada S; Villela, D1
Chang, CC; Chen, TY; Huang, SY; Hung, YC; Juan, WS; Lee, AC; Lee, AH; Lee, EJ; Lin, YW; Wu, TS1
Delgado Rodrigues, RN; Goulart, LI; Prieto Peres, MF1
Lin, L; Liu, T; Meng, T; Yuan, S; Zheng, Z1
Karsanova, SK; Yasnetsov, VV1
Arunakaran, J; Bavithra, S; Krishnamoorthy, G; Selvakumar, K; Sugantha Priya, E1
Baburamani, A; D'Agostino, I; Ek, J; Favero, G; Ghersi-Egea, JF; Gressens, P; Kratzer, I; La Rocca, MA; Manganozzi, L; Massano, D; Moretti, R; Pansiot, J; Pic, I; Rezzani, R; Rinaldi, VE; Rodella, LF; Spiri, D; Strazielle, N; Titomanlio, L; Vasiljevic, A; Zanin, A1
Antolín, I; Branco-Santos, J; Herrera, F; Letra-Vilela, R; Martin, V; Outeiro, TF; Puente-Moncada, N; Rocha, AM; Rodriguez, C; Sánchez-Sánchez, AM; Santa-Marta, M1
Cacabelos, R; Egea, J; Farré-Alins, V; López, MG; Marco-Contelles, J; Molz, S; Parada, E; Patiño, P; Ramos, E; Romero, A; Tasca, CI1
Chavan, S; Dey, G; Gopalakrishnan, L; Gowda, H; Kumar, M; Madugundu, AK; Mahadevan, A; Mathur, PP; Prasad, TS; Sathe, G; Shankar, SK; Yelamanchi, SD1
Parvez, S; Raisuddin, S; Vishnoi, S1
Bermudez, I; Csanova, A; Franklin, M; Hlavacova, N; Jezova, D; Li, Y; Sanchez, C1
Argueta, J; Benítez-King, G; Cercós, MG; Cruz-Garduño, R; Dorantes-Barrón, AM; Dubocovich, ML; Estrada-Reyes, R; Oikawa-Sala, J; Quero-Chávez, D; Solís-Chagoyán, H; Trueta, C; Valdés-Tovar, M1
Moody, AS; Sharma, B1
Ahn, JH; Chen, BH; Hwang, IK; Kang, IJ; Kim, DW; Kim, YM; Lee, CH; Lee, JC; Lee, TK; Lee, YL; Park, JH; Won, MH; Yan, BC1
Allemandi, DA; Carpentieri, AR; de Barboza, GED; Del Valle Bessone, C; Fajreldines, HD; Quinteros, DA; Tolosa de Talamoni, NG1
Chen, L; Ding, X; Hong, C; Lin, J; Liu, Q; Pang, Y; Wang, X; Xin, H; Zhang, X1
Aguilar, JJ; Carpentieri, AR; Sola, VM; Vazquez Mosquera, AP1
Baldin, SL; Bernardo, HT; de Farias, ACS; de Pieri Pickler, K; Dondossola, ER; Rico, EP1
Aljabali, AAA; Chellappan, DK; Dua, K; Goyal, R; Sarena, P; Sharma, A; Taliyan, R; Tambuwala, MM; Urmera, MT1
Antonenko, AK; Fursova, AZ; Kolosova, NG; Telegina, DV1
Afeche, SC; Cipolla-Neto, J; de Piazza Pimentel, D; Ferro, LF1
An, Y; Ding, L; Li, H; Song, S; Wang, C; Xia, X; Xia, Z; Zhou, X1
Caspi, Y; Hulshoff Pol, H; Kajala, K; Pantazopoulou, CK; Pieterse, CMJ; Prompers, JJ1

Reviews

16 review(s) available for glutamic acid and melatonin

ArticleYear
Neurotransmitter systems in the outer plexiform layer of mammalian retina.
    Neuroscience research. Supplement : the official journal of the Japan Neuroscience Society, 1988, Volume: 8

    Topics: Animals; Glutamates; Glutamic Acid; Melatonin; Neurotransmitter Agents; Rabbits; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Serotonin

1988
Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis.
    Journal of pineal research, 1993, Volume: 14, Issue:4

    Topics: Aging; Animals; Calcium; Free Radical Scavengers; Free Radicals; Glutamates; Glutamic Acid; Humans; Hydroxides; Melatonin; Nerve Degeneration

1993
In vitro and in vivo protective effects of melatonin against glutamate oxidative stress and neurotoxicity.
    Annals of the New York Academy of Sciences, 1997, Oct-15, Volume: 825

    Topics: Animals; Brain; Glutamic Acid; Humans; Melatonin; Neurons; Neuroprotective Agents; Oxidative Stress

1997
Neuroprotective action of the pineal hormone melatonin against excitotoxicity. Receptor abuse-dependent antagonism (RADA).
    Annals of the New York Academy of Sciences, 1997, Oct-15, Volume: 825

    Topics: Animals; Cerebrovascular Disorders; Glutamic Acid; Humans; Kainic Acid; Melatonin; Neuroprotective Agents; Neurotoxins; Pineal Gland; Rats; Receptors, Glutamate

1997
Metabotropic glutamate receptors negatively regulate melatonin synthesis in rat pinealocytes.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Mar-15, Volume: 18, Issue:6

    Topics: Animals; Cells, Cultured; Glutamic Acid; GTP-Binding Proteins; Melatonin; Norepinephrine; Pineal Gland; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Tissue Distribution

1998
[Autonomic regulation of melatonin synthesis through intrinsic glutaminergic systems in mammalian pineal glands].
    Seikagaku. The Journal of Japanese Biochemical Society, 1998, Volume: 70, Issue:5

    Topics: Animals; Circadian Rhythm; Excitatory Amino Acids; Glutamic Acid; Homeostasis; Humans; Melatonin; Pineal Gland

1998
Synaptic-like microvesicles, synaptic vesicle counterparts in endocrine cells, are involved in a novel regulatory mechanism for the synthesis and secretion of hormones.
    The Journal of experimental biology, 2000, Volume: 203, Issue:Pt 1

    Topics: Glutamic Acid; Melatonin; Organelles; Pineal Gland; Proton-Translocating ATPases; Signal Transduction; Synaptic Vesicles; Vacuolar Proton-Translocating ATPases

2000
[Intrinsic glutaminergic systems and its negative regulation of melatonin synthesis in mammalian pineal glands].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000, Volume: 45, Issue:3 Suppl

    Topics: Animals; Asparagine; Glutamic Acid; Melatonin; Pineal Gland; Signal Transduction

2000
Making (a) sense of non-visual ocular photoreception.
    Trends in neurosciences, 2003, Volume: 26, Issue:9

    Topics: Animals; Circadian Rhythm; Cryptochromes; Drosophila Proteins; Eye Proteins; Flavoproteins; Geniculate Bodies; Glutamic Acid; Melatonin; Neuropeptides; Photoreceptor Cells, Invertebrate; Photoreceptor Cells, Vertebrate; Pituitary Adenylate Cyclase-Activating Polypeptide; Pupil; Receptors, G-Protein-Coupled; Reflex; Retinal Ganglion Cells; Rod Opsins; Suprachiasmatic Nucleus

2003
A network of (autonomic) clock outputs.
    Chronobiology international, 2006, Volume: 23, Issue:1-2

    Topics: Adrenal Glands; Animals; Biological Clocks; Circadian Rhythm; Glutamic Acid; Humans; Liver; Melatonin; Models, Biological; Neurons; Oscillometry; Pineal Gland; Receptors, GABA; Suprachiasmatic Nucleus; Vasopressins

2006
A network of (autonomic) clock outputs.
    Chronobiology international, 2006, Volume: 23, Issue:3

    Topics: Animals; Autonomic Nervous System; Biological Clocks; Circadian Rhythm; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Melatonin; Neurons; Suprachiasmatic Nucleus; Vasopressins

2006
Pharmacologic approaches to treatment resistant depression: a re-examination for the modern era.
    Expert opinion on pharmacotherapy, 2010, Volume: 11, Issue:5

    Topics: Acetylcholine; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder, Major; Drug Delivery Systems; Drug Resistance; Glutamic Acid; Humans; Melatonin; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2010
Restless legs syndrome and pain disorders: what's in common?
    Current pain and headache reports, 2014, Volume: 18, Issue:11

    Topics: Calcium Channel Blockers; Diagnosis, Differential; Dopamine Agonists; Fibromyalgia; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypnotics and Sedatives; Iron; Melatonin; Migraine Disorders; Pain; Polyneuropathies; Restless Legs Syndrome; Serotonin; Sleep Deprivation; Vitamin D

2014
Glutamate Excitotoxicity and Oxidative Stress in Epilepsy: Modulatory Role of Melatonin.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2016, Volume: 35, Issue:4

    Topics: Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Melatonin; Neurotoxins; Oxidative Stress; Reactive Oxygen Species

2016
Circadian modulation of neuroplasticity by melatonin: a target in the treatment of depression.
    British journal of pharmacology, 2018, Volume: 175, Issue:16

    Topics: Animals; Circadian Rhythm; Depression; Glutamic Acid; Hippocampus; Humans; Melatonin; Neuronal Plasticity

2018
Why did glutamate, GABA, and melatonin become intercellular signalling molecules in plants?
    eLife, 2023, 06-20, Volume: 12

    Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Melatonin; Plants; Signal Transduction

2023

Trials

1 trial(s) available for glutamic acid and melatonin

ArticleYear
Reduced oxidative damage in ALS by high-dose enteral melatonin treatment.
    Journal of pineal research, 2006, Volume: 41, Issue:4

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Cell Line; Cytoprotection; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glutamic Acid; Humans; Male; Melatonin; Mice; Mice, Transgenic; Middle Aged; Neurons; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Survival Rate; Vitamin E

2006

Other Studies

70 other study(ies) available for glutamic acid and melatonin

ArticleYear
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
Immunocytochemical and circadian biochemical analysis of neuroactive amino acids in the pineal gland of the rat: effect of superior cervical ganglionectomy.
    Cell and tissue research, 1992, Volume: 269, Issue:3

    Topics: Alanine; Analysis of Variance; Animals; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; Circadian Rhythm; Endothelium; Ganglia, Sympathetic; Ganglionectomy; Glutamates; Glutamic Acid; Glutamine; Immunohistochemistry; Male; Melatonin; Neuroglia; Pineal Gland; Rats; Rats, Sprague-Dawley; Serine; Taurine

1992
Darkness stimulates rapid synthesis and release of melatonin in rat retina.
    Visual neuroscience, 1989, Volume: 3, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dark Adaptation; Diffusion; Glutamates; Glutamic Acid; Light; Melatonin; Rats; Rats, Inbred Strains; Retina; Serotonin; Tryptophan

1989
Dopamine-glutamic acid interaction in the anterior hypothalamus: modulatory effect of melatonin.
    Neuroreport, 1995, Mar-07, Volume: 6, Issue:4

    Topics: Animals; Cerebral Cortex; Dopamine; Glutamic Acid; Hypothalamus, Anterior; Male; Melatonin; Neurotransmitter Agents; Rats; Rats, Wistar

1995
Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity.
    Experimental neurology, 1995, Volume: 131, Issue:1

    Topics: Animals; Cerebellum; Excitatory Amino Acids; Glutamic Acid; Kainic Acid; Melatonin; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats

1995
Glutamate inhibition of the adrenergic-stimulated production of melatonin in rat pineal gland in vitro.
    Journal of neurochemistry, 1994, Volume: 62, Issue:6

    Topics: Amino Acids; Animals; Glutamates; Glutamic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Sprague-Dawley; Sympathomimetics

1994
The modulatory effect of melatonin on the dopamine-glutamate interaction in the anterior hypothalamus during ageing.
    Neuroreport, 1995, Nov-27, Volume: 6, Issue:17

    Topics: Aging; Amphetamine; Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Extracellular Space; Glutamic Acid; Hypothalamus, Anterior; Male; Melatonin; Rats; Rats, Wistar

1995
Melatonin prevents oxidative stress-induced cell death in hippocampal cells.
    Neuroreport, 1996, Sep-02, Volume: 7, Issue:13

    Topics: Animals; Benzimidazoles; Cell Death; Cell Survival; Clone Cells; DNA; DNA Damage; Fluorescent Dyes; Glutamic Acid; Hippocampus; Hydrogen Peroxide; Male; Melatonin; Neurons; Organ Culture Techniques; Oxidative Stress; Peroxides; Rats; Rats, Sprague-Dawley

1996
Microvesicle-mediated exocytosis of glutamate is a novel paracrine-like chemical transduction mechanism and inhibits melatonin secretion in rat pinealocytes.
    Journal of pineal research, 1996, Volume: 21, Issue:3

    Topics: Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Calcium; Cells, Cultured; Exocytosis; Glutamic Acid; Melatonin; Molecular Sequence Data; Neurons; Neurotoxins; Norepinephrine; Peptide Fragments; Pineal Gland; Potassium Chloride; Rats; Rats, Wistar; Receptors, Glutamate; Signal Transduction; Synaptic Vesicles

1996
N-acetyl-serotonin (normelatonin) and melatonin protect neurons against oxidative challenges and suppress the activity of the transcription factor NF-kappaB.
    Journal of pineal research, 1998, Volume: 24, Issue:3

    Topics: Animals; Cell Survival; Cerebellar Nuclei; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Hydrogen Peroxide; Melatonin; N-Methylaspartate; Neuroblastoma; Neurons; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Serotonin; Tumor Cells, Cultured

1998
Modulation of rat striatal glutamatergic response in search for new neuroprotective agents: evaluation of melatonin and some kynurenine derivatives.
    Brain research bulletin, 1998, Mar-15, Volume: 45, Issue:5

    Topics: Animals; Corpus Striatum; Electric Stimulation; Electrophysiology; Evoked Potentials; Glutamic Acid; Iontophoresis; Kynurenic Acid; Kynurenine; Male; Melatonin; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Reaction Time; Structure-Activity Relationship

1998
Modification of nitric oxide synthase activity and neuronal response in rat striatum by melatonin and kynurenine derivatives.
    Journal of neuroendocrinology, 1998, Volume: 10, Issue:4

    Topics: Animals; Corpus Striatum; Electric Stimulation; Glutamic Acid; Kynurenine; Melatonin; Neurons; Nitric Oxide Synthase; Rats; Somatosensory Cortex

1998
Acetylcholine triggers L-glutamate exocytosis via nicotinic receptors and inhibits melatonin synthesis in rat pinealocytes.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jul-01, Volume: 18, Issue:13

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Arylamine N-Acetyltransferase; Atropine; Bungarotoxins; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cells, Cultured; Diltiazem; Exocytosis; Glutamic Acid; Melatonin; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nifedipine; Nitrendipine; Oxotremorine; Parasympathetic Nervous System; Pineal Gland; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine; Synaptic Vesicles; Tubocurarine

1998
D-aspartate modulates melatonin synthesis in rat pinealocytes.
    Neuroscience letters, 1998, Jun-19, Volume: 249, Issue:2-3

    Topics: Animals; Arylamine N-Acetyltransferase; Aspartic Acid; Bucladesine; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Conditioned; Cyclic AMP; Dose-Response Relationship, Drug; Glutamic Acid; Melatonin; Organ Culture Techniques; Pineal Gland; Rats; Rats, Wistar; Time Factors

1998
Stimuli which entrain the circadian clock of the neonatal Syrian hamster in vivo regulate the phosphorylation of the transcription factor CREB in the suprachiasmatic nucleus in vitro.
    The European journal of neuroscience, 1998, Volume: 10, Issue:3

    Topics: Animals; Animals, Newborn; Blotting, Western; Cells, Cultured; Circadian Rhythm; Cricetinae; Cyclic AMP Response Element-Binding Protein; Dopamine; Glutamic Acid; Immunohistochemistry; Melatonin; Mesocricetus; Phenotype; Phosphorylation; Rats; Suprachiasmatic Nucleus

1998
CREB in the mouse SCN: a molecular interface coding the phase-adjusting stimuli light, glutamate, PACAP, and melatonin for clockwork access.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Dec-15, Volume: 18, Issue:24

    Topics: Animals; Biological Clocks; Cyclic AMP Response Element-Binding Protein; Glutamic Acid; In Vitro Techniques; Light; Male; Melatonin; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Motor Activity; Neuropeptides; Phosphorylation; Photic Stimulation; Pituitary Adenylate Cyclase-Activating Polypeptide; Suprachiasmatic Nucleus

1998
Inducible cyclic AMP early repressor protein in rat pinealocytes: a highly sensitive natural reporter for regulated gene transcription.
    Molecular pharmacology, 1999, Volume: 56, Issue:2

    Topics: Acetylcholine; Adenosine; Animals; Cyclic AMP Response Element Modulator; DNA-Binding Proteins; Gene Expression Regulation; Glutamic Acid; In Vitro Techniques; Male; Melatonin; Neuropeptides; Pineal Gland; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Repressor Proteins; Transcription, Genetic; Vasoactive Intestinal Peptide

1999
Vesicular monoamine transporter 1 is responsible for storage of 5-hydroxytryptamine in rat pinealocytes.
    Journal of neurochemistry, 1999, Volume: 73, Issue:6

    Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Cells, Cultured; Energy Metabolism; Exocytosis; Glutamic Acid; Macrolides; Melatonin; Membrane Glycoproteins; Membrane Transport Proteins; Neurons; Neuropeptides; Nitriles; Norepinephrine; PC12 Cells; Pineal Gland; Proton-Translocating ATPases; Rats; Rats, Wistar; Reserpine; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Vesicular Biogenic Amine Transport Proteins; Vesicular Monoamine Transport Proteins

1999
Hydroxyindole-O-methyltransferase is another target for L-glutamate-evoked inhibition of melatonin synthesis in rat pinealocytes.
    Brain research, 1999, Dec-11, Volume: 850, Issue:1-2

    Topics: Acetylserotonin O-Methyltransferase; Animals; Arylamine N-Acetyltransferase; Blotting, Northern; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

1999
Melatonin disrupts circadian rhythms of glutamate and GABA in the neostriatum of the aware rat: a microdialysis study.
    Journal of pineal research, 2000, Volume: 29, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antioxidants; Arginine; Chromatography, High Pressure Liquid; Circadian Rhythm; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Male; Melatonin; Microdialysis; Neostriatum; Rats; Rats, Wistar; Taurine; Wakefulness

2000
The effects of melatonin in glutamate-induced neurotoxicity of rat cerebellar granular cell culture.
    Japanese journal of pharmacology, 2000, Volume: 84, Issue:4

    Topics: Animals; Animals, Newborn; Antioxidants; Cell Death; Cerebellum; Glutamic Acid; Melatonin; Neurons; Rats; Rats, Sprague-Dawley

2000
Antagonistic effects of melatonin on glutamate release and neurotoxicity in cerebral cortex.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:9

    Topics: Aging; Animals; Cells, Cultured; Cerebral Cortex; Glutamic Acid; Melatonin; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Synaptosomes

1999
Calcium-dependent effects of melatonin inhibition of glutamatergic response in rat striatum.
    Journal of neuroendocrinology, 2001, Volume: 13, Issue:5

    Topics: Amlodipine; Animals; Anticonvulsants; Biological Transport; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Corpus Striatum; Diltiazem; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; In Vitro Techniques; Ionophores; Iontophoresis; Male; Melatonin; omega-Conotoxins; Rats; Rats, Wistar; Synaptosomes; Tritium

2001
[Antagonistic effects of melatonin on glutamate-induced neurotoxicity in rat hippocampal neurons].
    Sheng li xue bao : [Acta physiologica Sinica], 1999, Volume: 51, Issue:4

    Topics: Animals; Evoked Potentials; Female; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Melatonin; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1999
[Melatonin decreases the release of amino acid transmitters in hypoxic rat cortical slice].
    Sheng li xue bao : [Acta physiologica Sinica], 1999, Volume: 51, Issue:4

    Topics: Animals; Aspartic Acid; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Male; Melatonin; Random Allocation; Rats; Rats, Sprague-Dawley

1999
N1-acetyl-N2-formyl-5-methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyloid beta-Peptides; Animals; Antioxidants; Cell Death; Cells, Cultured; Chelating Agents; Deoxyguanosine; Ferrous Compounds; Free Radicals; Glutamic Acid; Hydrogen Peroxide; Kynuramine; Lipid Peroxidation; Liver; Melatonin; Metals, Heavy; Models, Biological; Neurons; Peptide Fragments; Rats

2001
Glutamate induces oxidative stress not mediated by glutamate receptors or cystine transporters: protective effect of melatonin and other antioxidants.
    Journal of pineal research, 2001, Volume: 31, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Brain; Carrier Proteins; Cystine; Glutamic Acid; Glutathione; Male; Melatonin; Oxidative Stress; Rats; Rats, Wistar; Receptors, Glutamate

2001
Melatonin nocturnal surge modulates nicotinic receptors and nicotine-induced [3H]glutamate release in rat cerebellum slices.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:2

    Topics: Adrenergic beta-Antagonists; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Choline; Circadian Rhythm; Darkness; Glutamic Acid; In Vitro Techniques; Light; Male; Melatonin; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Propranolol; Pyridines; Rats; Rats, Wistar; Receptors, Nicotinic

2003
Neuroprotection against Abeta and glutamate toxicity by melatonin: are GABA receptors involved?
    Neurotoxicity research, 2003, Volume: 5, Issue:5

    Topics: Amyloid beta-Peptides; Animals; Antioxidants; Benzothiazoles; Chick Embryo; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; Glutamic Acid; Light; Melatonin; Neurons; Peptide Fragments; Picrotoxin; Receptors, GABA; Retina; Scattering, Radiation; Thiazoles

2003
Glutamatergic clock output stimulates melatonin synthesis at night.
    The European journal of neuroscience, 2004, Volume: 19, Issue:2

    Topics: Animals; Biological Clocks; Darkness; Glutamic Acid; Male; Melatonin; Pineal Gland; Rats; Rats, Wistar

2004
Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain.
    Current biology : CB, 2004, Apr-06, Volume: 14, Issue:7

    Topics: Animals; Brain; DNA Primers; Drosophila; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Fluorescence; Gene Silencing; Glutamic Acid; Humans; Melatonin; Microscopy, Electron, Scanning; Movement; Nerve Degeneration; Neuropil; Oxidative Stress; Paraquat; Reverse Transcriptase Polymerase Chain Reaction; Riluzole; RNA Interference

2004
Effect of melatonin on the retinal glutamate/glutamine cycle in the golden hamster retina.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:15

    Topics: Animals; Biological Transport; Cricetinae; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Melatonin; Mesocricetus; Models, Biological; Retina

2004
Antioxidant activity and neuroprotective effects of zolpidem and several synthesis intermediates.
    Free radical research, 2004, Volume: 38, Issue:12

    Topics: Animals; Antioxidants; Brain; Cell Death; Cells, Cultured; Chromans; Estradiol; Ferrous Compounds; Glutamic Acid; Hippocampus; Lipid Peroxidation; Liver; Male; Melatonin; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Proteins; Pyridines; Rats; Reactive Oxygen Species; Structure-Activity Relationship; Zolpidem

2004
Effect of glaucoma on the retinal glutamate/glutamine cycle activity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Animals; Glaucoma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hyaluronic Acid; Intraocular Pressure; Male; Melatonin; Rats; Rats, Wistar; Retina

2005
Modulation by melatonin of glutamatergic synaptic transmission in the carp retina.
    The Journal of physiology, 2005, Dec-15, Volume: 569, Issue:Pt 3

    Topics: Animals; Carps; Cyclic GMP; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; Light; Melatonin; Membrane Potentials; Receptor, Melatonin, MT1; Receptors, Glutamate; Retina; Retinal Cone Photoreceptor Cells; Retinal Horizontal Cells; Synaptic Transmission; Tryptamines; Vision, Ocular

2005
Neuroprotective agents: is effective on toxicity in glial cells?
    Cellular and molecular neurobiology, 2007, Volume: 27, Issue:2

    Topics: Animals; Anticonvulsants; Cells, Cultured; Drug Interactions; Glutamic Acid; Indazoles; L-Lactate Dehydrogenase; Melatonin; Neuroglia; Neuroprotective Agents; Nitrates; Rats; Rats, Sprague-Dawley; Riluzole

2007
Melatonin prevents glutamate-induced oxytosis in the HT22 mouse hippocampal cell line through an antioxidant effect specifically targeting mitochondria.
    Journal of neurochemistry, 2007, Volume: 100, Issue:3

    Topics: Animals; Antioxidants; Cell Death; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Hippocampus; Melatonin; Mice; Microscopy, Electron, Transmission; Mitochondria; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Signal Transduction

2007
Cytoprotective effects of melatonin on C6 astroglial cells exposed to glutamate excitotoxicity and oxidative stress.
    Journal of pineal research, 2008, Volume: 45, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Astrocytes; bcl-2-Associated X Protein; Blotting, Western; Calcium; Cell Line, Tumor; Cell Survival; Glutamic Acid; Melatonin; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Reverse Transcriptase Polymerase Chain Reaction

2008
Activation of 5-HT2C receptors acutely induces Per1 gene expression in the rat SCN in vitro.
    Brain research, 2008, May-13, Volume: 1209

    Topics: Animals; Cell Cycle Proteins; Circadian Rhythm; Gene Expression Regulation; Glutamic Acid; Light Signal Transduction; Male; Melatonin; Organ Culture Techniques; Period Circadian Proteins; Proto-Oncogene Proteins c-fos; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Suprachiasmatic Nucleus; Synaptic Transmission

2008
Glutamate transporter-mediated glutamate secretion in the mammalian pineal gland.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Oct-22, Volume: 28, Issue:43

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cesium; Chlorides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exocytosis; Glutamic Acid; In Vitro Techniques; Kainic Acid; Macrolides; Magnesium; Male; Melatonin; Membrane Potentials; Pineal Gland; Potassium Chloride; Rats; Rats, Sprague-Dawley

2008
An autonomous circadian clock in the inner mouse retina regulated by dopamine and GABA.
    PLoS biology, 2008, Oct-14, Volume: 6, Issue:10

    Topics: Acetylcholine; Animals; Cell Cycle Proteins; Chromatography, High Pressure Liquid; Circadian Rhythm; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Immunohistochemistry; In Situ Hybridization; Luciferases; Melatonin; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nuclear Proteins; Period Circadian Proteins; Photoreceptor Cells, Vertebrate; Recombinant Fusion Proteins; Retina; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors

2008
Role of glutamate and its receptors and insulin-like growth factors in hypoxia induced periventricular white matter injury.
    Glia, 2010, Volume: 58, Issue:5

    Topics: Animals; Animals, Newborn; Antioxidants; Brain; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glutamic Acid; Hypoxia; Interleukin-1beta; Melatonin; Microglia; Rats; Receptors, Glutamate; RNA Interference; RNA, Messenger; Somatomedins; Time Factors; Transfection; Tumor Necrosis Factor-alpha

2010
The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors.
    Journal of pineal research, 2010, Volume: 48, Issue:2

    Topics: Animals; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Calcium; Caspase 8; Cells, Cultured; Glutamic Acid; Hydrogen Peroxide; Melatonin; Membrane Potential, Mitochondrial; Mice; Motor Neurons; Oxidative Stress; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; Tryptamines; Tumor Necrosis Factor-alpha

2010
Melatonin: a novel neuroprotectant for the treatment of glaucoma.
    Journal of pineal research, 2010, Volume: 48, Issue:4

    Topics: Animals; Arginine; gamma-Aminobutyric Acid; Glaucoma; Glutamate Decarboxylase; Glutamic Acid; Histocytochemistry; Intraocular Pressure; Kinetics; Male; Melatonin; Neuroprotective Agents; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells

2010
Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways.
    BMC neuroscience, 2010, Jun-03, Volume: 11

    Topics: Acetamides; Analysis of Variance; Animals; Central Nervous System Depressants; Electroshock; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Indoles; Melatonin; Pyridines; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Melatonin; Stress, Physiological; Synaptosomes

2010
Clock genes, melanopsins, melatonin, and dopamine key enzymes and their modulation by light and glutamate in chicken embryonic retinal cells.
    Chronobiology international, 2011, Volume: 28, Issue:2

    Topics: Animals; Biological Clocks; Cell Survival; Cells, Cultured; Chick Embryo; Circadian Rhythm; CLOCK Proteins; Dopamine; Gene Expression; Glutamic Acid; Light; Melatonin; Photoperiod; Retina; Rod Opsins; Tyrosine 3-Monooxygenase

2011
Hypoxia-induced cellular and vascular changes in the nucleus tractus solitarius and ventrolateral medulla.
    Journal of neuropathology and experimental neurology, 2011, Volume: 70, Issue:3

    Topics: Animals; Glutamic Acid; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; Medulla Oblongata; Melatonin; Neurons; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Ionotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Vascular Endothelial Growth Factor A

2011
Melatonin regulates the calcium-buffering proteins, parvalbumin and hippocalcin, in ischemic brain injury.
    Journal of pineal research, 2012, Volume: 53, Issue:4

    Topics: Animals; Calcium; Cell Death; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hippocalcin; Hippocampus; Infarction, Middle Cerebral Artery; Male; Melatonin; Mice; Neurons; Neuroprotective Agents; Parvalbumins; Rats; Rats, Sprague-Dawley

2012
Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity.
    Fitoterapia, 2013, Volume: 87

    Topics: Acquired Immunodeficiency Syndrome; Brain; Cell Line; Cell Survival; Dopamine; Fabaceae; Glutamic Acid; HIV; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Leukocytes, Mononuclear; Melatonin; Molecular Structure; Plant Extracts; Psychotropic Drugs; Seeds; Serotonin; Tryptophan; Virus Replication

2013
[Protective action of melatonin in experimental glaucoma in rats].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2013, Volume: 59, Issue:1

    Topics: Animals; Antioxidants; Aspartic Acid; Chromatography, Ion Exchange; Epinephrine; gamma-Aminobutyric Acid; Glaucoma; Glutamic Acid; Glycine; Intraocular Pressure; Male; Melatonin; Neuroprotective Agents; Neurotransmitter Agents; Rats; Retina; Vitreous Body

2013
Modulation of pineal melatonin synthesis by glutamate involves paracrine interactions between pinealocytes and astrocytes through NF-κB activation.
    BioMed research international, 2013, Volume: 2013

    Topics: Animals; Astrocytes; Calcium; Cell Separation; Cells, Cultured; Electrophoretic Mobility Shift Assay; Glutamic Acid; Immunohistochemistry; Male; Melatonin; Models, Biological; NF-kappa B; Paracrine Communication; Pineal Gland; Proline; Rats; Rats, Wistar; Receptors, Glutamate; Thiocarbamates

2013
Melatonin improves neuroplasticity by upregulating the growth-associated protein-43 (GAP-43) and NMDAR postsynaptic density-95 (PSD-95) proteins in cultured neurons exposed to glutamate excitotoxicity and in rats subjected to transient focal cerebral isch
    Journal of pineal research, 2014, Volume: 56, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; Cells, Cultured; Disks Large Homolog 4 Protein; GAP-43 Protein; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Male; Melatonin; Membrane Proteins; Neuronal Plasticity; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Up-Regulation

2014
Effects of endogenous melatonin on glutamate and GABA rhythms in the striatum of unilateral 6-hydroxydopamine-lesioned rats.
    Neuroscience, 2015, Feb-12, Volume: 286

    Topics: Animals; Chromatography, Liquid; Circadian Rhythm; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Male; Melatonin; Oxidopamine; Rats; Rats, Sprague-Dawley

2015
[A new approach to the search for vestibuloprotectors].
    Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine, 2015, Volume: 49, Issue:1

    Topics: Acetamides; Animals; Drug Design; Glutamic Acid; Humans; Melatonin; Motion Sickness; Picolines; Promethazine; Rats; Receptors, GABA-A; Receptors, Melatonin; Scopolamine

2015
Effect of Melatonin on Glutamate: BDNF Signaling in the Cerebral Cortex of Polychlorinated Biphenyls (PCBs)-Exposed Adult Male Rats.
    Neurochemical research, 2015, Volume: 40, Issue:9

    Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium Channels, N-Type; Calpain; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Male; Melatonin; Polychlorinated Biphenyls; Rats; Receptors, Glutamate; RNA, Messenger; Signal Transduction

2015
Melatonin reduces excitotoxic blood-brain barrier breakdown in neonatal rats.
    Neuroscience, 2015, Dec-17, Volume: 311

    Topics: Animals; Animals, Newborn; Blood-Brain Barrier; Capillary Permeability; Disease Models, Animal; Excitatory Amino Acid Agents; Gene Expression; Glutamic Acid; Immunohistochemistry; Melatonin; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley

2015
Distinct roles of N-acetyl and 5-methoxy groups in the antiproliferative and neuroprotective effects of melatonin.
    Molecular and cellular endocrinology, 2016, 10-15, Volume: 434

    Topics: 5-Methoxytryptamine; Animals; Antioxidants; Autophagy; Cell Line; Cell Proliferation; Cell Survival; Glutamic Acid; HEK293 Cells; Hippocampus; Humans; Melatonin; Mice; Neuroprotective Agents

2016
Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices.
    Neurotoxicology, 2016, Volume: 57

    Topics: Analysis of Variance; Animals; Antioxidants; Cell Death; Deoxyglucose; Dose-Response Relationship, Drug; Extracellular Fluid; Glucose; Glutamic Acid; Glutathione; Hippocampus; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Melatonin; Oxygen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2016
Characterization of human pineal gland proteome.
    Molecular bioSystems, 2016, 11-15, Volume: 12, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Female; Glutamic Acid; Humans; Male; Melatonin; Metabolic Networks and Pathways; Middle Aged; Period Circadian Proteins; Pineal Gland; Proteome; Proteomics; Tandem Mass Spectrometry; Young Adult

2016
Contrasting effects of vortioxetine and paroxetine on pineal gland biochemistry in a tryptophan-depletion model of depression in female rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 10-03, Volume: 79, Issue:Pt B

    Topics: Administration, Oral; Animals; Antidepressive Agents, Second-Generation; Depressive Disorder; Disease Models, Animal; Female; Glutamic Acid; Melatonin; Norepinephrine; Paroxetine; Pineal Gland; Piperazines; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA-Binding Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Tryptophan; Vortioxetine

2017
Multi-metal, Multi-wavelength Surface-Enhanced Raman Spectroscopy Detection of Neurotransmitters.
    ACS chemical neuroscience, 2018, 06-20, Volume: 9, Issue:6

    Topics: Dopamine; Glutamic Acid; Gold; Melatonin; Metal Nanoparticles; Neurotransmitter Agents; Silver; Spectrum Analysis, Raman; Surface Properties

2018
Melatonin improves vascular cognitive impairment induced by ischemic stroke by remyelination via activation of ERK1/2 signaling and restoration of glutamatergic synapses in the gerbil hippocampus.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Animals; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Cell Death; Cognitive Dysfunction; Gerbillinae; Glutamic Acid; Hippocampus; Ischemic Attack, Transient; Male; MAP Kinase Signaling System; Melatonin; Models, Animal; Myelin Sheath; Neurons; Oligodendroglia; Remyelination; Stroke; Synapses

2018
Protective role of melatonin on retinal ganglionar cell: In vitro an in vivo evidences.
    Life sciences, 2019, Feb-01, Volume: 218

    Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Chick Embryo; Glutamic Acid; In Vitro Techniques; Melatonin; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Rabbits; Retinal Degeneration; Retinal Ganglion Cells

2019
Several biological benefits of the low color temperature light-emitting diodes based normal indoor lighting source.
    Scientific reports, 2019, 05-17, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Animals; Cold Temperature; Color; Glutamic Acid; Hair; Household Articles; Humans; Light; Lighting; Male; Melatonin; Mice; Mice, Inbred C57BL; Ocular Physiological Phenomena; Quality of Life; Regeneration; Semiconductors; Wound Healing; Young Adult

2019
Melatonin is an effective protector of gingival cells damaged by the cytotoxic effect of glutamate and DL-buthionine sulfoximine.
    Journal of periodontal research, 2021, Volume: 56, Issue:1

    Topics: Animals; Buthionine Sulfoximine; Glutamic Acid; Glutathione; Melatonin; Rats; Rats, Wistar

2021
Melatonin Pretreatment Protects Against Status epilepticus, Glutamate Transport, and Oxidative Stress Induced by Kainic Acid in Zebrafish.
    Molecular neurobiology, 2022, Volume: 59, Issue:1

    Topics: Amino Acid Transport System X-AG; Animals; Antioxidants; Catalase; Glutamic Acid; Glutathione; Kainic Acid; Melatonin; Neurons; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Status Epilepticus; Superoxide Dismutase; Zebrafish

2022
Chronic Light-Distorted Glutamate-Cortisol Signaling, Behavioral and Histological Markers, and Induced Oxidative Stress and Dementia: An Amelioration by Melatonin.
    ACS chemical neuroscience, 2022, 06-01, Volume: 13, Issue:11

    Topics: Animals; Biomarkers; Circadian Rhythm; Dementia; Dextromethorphan; Glutamic Acid; Hydrocortisone; Light; Melatonin; Mifepristone; N-Methylaspartate; Oxidative Stress; Rats; Rats, Wistar

2022
The glutamate/GABA system in the retina of male rats: effects of aging, neurodegeneration, and supplementation with melatonin and antioxidant SkQ1.
    Biogerontology, 2022, Volume: 23, Issue:5

    Topics: Aging; Aminobutyrates; Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Macular Degeneration; Male; Melatonin; Rats; Rats, Wistar; Retina

2022
Pineal Cells Dissociation and Culture: Isolated Pinealocytes, Isolated Astrocytes, and Co-culture.
    Methods in molecular biology (Clifton, N.J.), 2022, Volume: 2550

    Topics: Angiotensins; Animals; Astrocytes; Cells, Cultured; Coculture Techniques; Glutamic Acid; Mammals; Melatonin; Pineal Gland; Rats; Rats, Wistar

2022
The neuroprotective effect of melatonin in glutamate excitotoxicity of R28 cells and mouse retinal ganglion cells.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Animals; Glaucoma; Glutamic Acid; Melatonin; Mice; N-Methylaspartate; Neuroprotective Agents; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells

2022