glutamic acid has been researched along with lysine in 1098 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (5.28) | 18.7374 |
| 1990's | 265 (24.13) | 18.2507 |
| 2000's | 502 (45.72) | 29.6817 |
| 2010's | 231 (21.04) | 24.3611 |
| 2020's | 42 (3.83) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Bonnemain, JL; Chollet, JF; Delétage, C; Faucher, M; Miginiac, L | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Çakmak, R; Durdagi, S; Ekinci, D; Sentürk, M; Topal, G | 1 |
| Anthony, A; Augustyn, E; Bauer, J; Campbell, J; Chien, HC; Colas, C; Finke, K; Flint, A; Fotiadis, D; Giacomini, KM; Hall, C; Hansen, L; Heeren, N; Hernandez, C; Schlessinger, A; Springer, S; Stoner, L; Thomas, AA; Venteicher, B; Zur, AA | 1 |
| Nehrke, KW; Platt, T; Seifried, SE | 1 |
| Dierks, T; Krämer, R; Salentin, A; Stappen, R | 1 |
| Andersson, H; Bakker, E; von Heijne, G | 1 |
| Dvoráková, M; Kotyk, A | 1 |
| Crespeau, H; Ferri, G; Galliano, M; Minchiotti, L; Porta, F; Rochu, D; Stoppini, M | 1 |
| Colléaux, Y; Henry, Y; Sève, B | 1 |
| Brewer, HB; Lohse, P; Rader, DJ | 1 |
| Knight, BL; McCarthy, SN; Patel, DD; Soutar, AK; Sun, XM; Webb, JC | 1 |
| Dauth, J; Nkhumeleni, FS; Pitout, MJ; Raubenheimer, EJ; Smith, PD; van Heerden, WF | 1 |
| Noll, D; Roberts, MF; Robertson, DE | 1 |
| Banci, L; Cabelli, DE; Fisher, CL; Getzoff, ED; Hallewell, RA; Parge, HE; Viezzoli, MS | 1 |
| Engstrand, C; Forsman, C; Liang, Z; Lindskog, S | 1 |
| Chevallier, MR; Horák, J; Kotyk, A; Sychrová, H | 1 |
| Cohen, GB; Oprian, DD; Robinson, PR; Zhukovsky, EA | 1 |
| Acquila, M; Krepelová, A; Mori, P; Vorlová, Z | 1 |
| Arakawa, F; Arakawa, K; Araki, K; Kaneko, S; Matsunaga, A; Moriyama, K; Sasaki, J; Takada, Y | 1 |
| Burke, GT; Chu, YC; Katsoyannis, PG; Zong, L | 1 |
| Palou, A; Picó, C; Pons, A | 1 |
| Inouhe, M; Ishikawa, Y; Joho, M; Kunikane, M; Murayama, T; Tohoyama, H | 1 |
| Saijo, T; Tanaka, K; Vockley, J; Yokota, I | 1 |
| Adler, SA; Jarvik, JW; Suhan, JP; Taillon, BE | 1 |
| Jeleniewicz, K; Maciejewska-Kozak, H; Szczepaniak, S | 1 |
| Chandy, M; Nagaraj, R; Pillai, VN; Sitaram, N | 1 |
| Hervé, M; Lebourguais, O; Tran-Dinh, S; Wietzerbin, J | 1 |
| Crielaard, W; de Vrij, W; Heyne, RI; Konings, WN | 1 |
| Caprio, J; Wegert, S | 1 |
| Hirose, T; Koga, M; Matsumoto, K; Sato, B | 1 |
| Anglés-Cano, E; Fleury, V | 1 |
| Carter, AJ; Müller, RE | 1 |
| Blouquit, Y; Bursaux, E; Delaunay, J; Driancourt, C; Vasseur, C; Wajcman, H; Yannoukakos, D | 1 |
| Caffrey, MS; Cusanovich, MA | 1 |
| Ji, I; Ji, TH; Yoo, J | 1 |
| Kameyama, M; Sawada, H; Seriu, N; Sugiyama, H; Udaka, F | 1 |
| Large, PJ; Robertson, A | 1 |
| Birckbichler, PJ; Greenberg, CS; Rice, RH | 1 |
| Heiligenberg, W; Kawasaki, M; Keller, CH; Metzner, W | 1 |
| Ball, E; Durston, J; Hennessey, E; Kyrtatas, V; Molloy, J; Reedy, M; Sparrow, J; White, D | 1 |
| Nicholson, BH; Savva, D; Tárnoky, AL | 1 |
| Burgess, WH; Donohue, PJ; Jaye, M; Ravera, M; Shaheen, AM; Winkles, JA | 1 |
| Ishii, Y; Nishida, N; Sawai, T; Tachibana, K; Tsukamoto, K; Ujiie, K; Yamazaki, N | 1 |
| Hartman, FC; Larimer, FW; Mural, RJ; Soper, TS | 1 |
| Collen, D; Lijnen, HR; Nelles, L; Van Hoef, B | 1 |
| Eisensmith, RC; Güttler, F; Okano, Y; Wang, T; Woo, SL | 1 |
| Kikura, R; Ohno, R; Sawai, T; Tsukamoto, K | 1 |
| Fong, YL; Soderling, TR | 1 |
| Ferri, G; Galliano, M; Iadarola, P; Minchiotti, L; Zepponi, E | 1 |
| Friedman, P; High, KA; Jagadeeswaran, P; Lechner, K; Mahr, G; Monroe, DM; Reddy, SV; Roberts, HR; Watzke, HH; Welsch, DJ | 1 |
| Heikinheimo, P; Heinonen, J; Lahti, R; Meyer, P; Pitkäranta, T; Pohjanoksa, K; Salminen, T | 1 |
| Ellerby, LM; Escobar, WA; Fink, AL; Mitchinson, C; Wells, JA | 1 |
| Basu, J; Chakrabarti, P; Kundu, M; Mazumder, C | 1 |
| Birnbaum, D; Bode, R; Schmidt, H | 1 |
| Hamano, S; Morita, K; Oka, M; Teraoka, K | 1 |
| Fujiwara, K; Maita, T; Matsuda, G; Onishi, H | 1 |
| Christensen, H; Gibson, RM; Waley, SG | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Suzuki, F; Yasumoto, K | 1 |
| Felipe, A; Remesar, X; Viñas, O | 1 |
| Sasaki, Y | 1 |
| Bosron, WF; Crabb, DW; Edenberg, HJ; Li, TK | 1 |
| Hardick, CP; Sifers, RN; Woo, SL | 1 |
| Arai, K; Franco, MH; Freitas, MJ; Huss, K; Madison, J; Putnam, FW; Salzano, FM; Santos, SE | 1 |
| Bakken, V; Högh, BT; Jensen, HB | 1 |
| Clore, GM; Dodt, J; Driscoll, PC; Folkers, PJ; Gronenborn, AM; Köhler, S | 1 |
| Kaiser, DA; Pollard, TD; Vandekerckhove, JS | 1 |
| Brew, K; Chin, D | 1 |
| Nagamatsu, A; Ohki, H; Shimeno, H; Soeda, S | 1 |
| Carvounis, CP; Carvounis, G; Wilk, BJ | 1 |
| Harano, K; Harano, T; Imai, K; Ohkushi, T; Ueda, S | 1 |
| Altay, C; Gurgey, A; Huisman, TH; Kilinç, Y; Kumi, M; Kutlar, A; Webber, BB; Wilson, JB | 1 |
| Bowring, MA; Foreman, JW; Lee, J; McNamara, PD; Rea, C; Segal, S | 1 |
| Beasty, AM; Hurle, MR; Manz, JT; Matthews, CR; Onuffer, JJ; Stackhouse, T | 1 |
| Stadtman, TC; Wittwer, AJ | 1 |
| Adams, MB; Harig, JM; Rajendran, VM; Ramaswamy, K | 1 |
| Colanduoni, J; Nissan, R; Villafranca, JJ | 1 |
| Foreman, RC | 1 |
| Makino, Y; Shirahama, S; Sugawara, Y; Takada, A; Takada, Y | 1 |
| Adachi, K; Asakura, T; Harano, T; Kim, J; Travitz, R | 1 |
| Collen, D; Holmes, WE; Lijnen, HR; Nelles, L; Van Hoef, B | 1 |
| Arrieta, A; Bonilla, E; Prasad, AL | 1 |
| Acevedo, M; Armstrong, WM; Corcia, A; Lyall, V | 1 |
| Castellani, AA; Ferri, G; Galliano, M; Iadarola, P; Minchiotti, L; Zapponi, MC | 1 |
| Bubis, J; Neitzel, JJ; Saraswat, LD; Taylor, SS | 1 |
| Bauer, SC; Bild, GS; Borgmeyer, JR; Huynh, QK; Kishore, GM | 1 |
| Arai, K; Huss, K; Ishioka, N; Madison, J; Putnam, FW; Takahashi, N | 1 |
| Adhya, S; Chaudhary, VK; FitzGerald, DJ; Jinno, Y; Kondo, T; Pastan, I | 1 |
| Arwert, F; Bank, RA; Crusius, BC; Meuwissen, SG; Pronk, JC; Zwiers, T | 1 |
| Brantly, M; Courtney, M; Crystal, RG | 1 |
| Soman, J; Suresh, CG; Vijayan, M | 1 |
| Akerblom, HK; Dukes, M; Hekali, R; Käär, ML; Lehmann, H; Puukka, R | 1 |
| Lal, DN; Srivastava, AS | 1 |
| Fujita, S; Kobayashi, Y; Ohta, Y; Saito, S | 1 |
| Takada, A; Takada, Y | 1 |
| Raczyńska-Bojanowska, K; Sawnor-Korszyńska, D | 1 |
| Winkler, HH; Zahorchak, RJ | 1 |
| Ishikawa, Y; Kaiser-Kupfer, MI; Kuwabara, T | 1 |
| Bridges, CD; Chytil, F; Olson, JA; Packer, L; Wolf, G | 1 |
| Jackson, S; Potter, LM; Stas, RJ | 1 |
| Fukui, H; Harano, K; Harano, T; Imai, K; Seki, M; Shibata, S; Tsuneshige, A; Ueda, S; Yamada, H | 1 |
| Anderson, JM; Kagan, HM; Williams, MA; Williamson, PR | 1 |
| Coy, DH; Hirst, BH | 1 |
| Crozier, GL; Freedland, RA; Hicks, BL; Meijer, AJ | 1 |
| Barton, KN; Blachly-Dyson, E; Boucher, PD; Carter, L; Forte, M; Petrak, M; Price, J; Reddy, G; Smith, MD; Verner, K | 1 |
| Gupta, PD; Vijayalakshmi, V | 1 |
| Cai, Y; Ewan, RC; Zimmerman, DR | 1 |
| Eggeling, L; Kronemeyer, W; Sahm, H; Vrljic, M | 1 |
| Baker, PJ; Britton, KL; Engel, PC; Martin, S; Rice, DW; Wang, XG | 1 |
| Bernier, M; Egan, JM; Henderson, TE | 1 |
| Gandbhir, M; Marlière, P; Mutzel, R; Rasched, I | 1 |
| Chang, YF; Charles, AK | 1 |
| Bolívar, M; Delgado, AV; Salcedo, J; Vera, P | 1 |
| Casals, T; Chillón, M; Dörk, T; Estivill, X; Nunes, V; Tümmler, B | 1 |
| Seefeldt, LC | 1 |
| Böhm, G; Jaenicke, R; Tomschy, A | 1 |
| Albert, I; Ewald, G; Leibl, W; Michel, H; Rutherford, AW | 1 |
| Kotyk, A | 1 |
| Knight, BL; Patel, DD; Soutar, AK | 1 |
| Jetten, MS; Sinskey, AJ | 1 |
| Arlaud, GJ; Fontecilla-Camps, JC; Gaboriaud, C; Gagnon, J; Lacroix, M; Rossi, V; Ulrich, J | 1 |
| Hu, B; Mooney, D; Senatorov, V | 1 |
| Angelo, S; Devés, R | 1 |
| Li, F; Owens, N; Verdoorn, TA | 1 |
| Abbruzzese, A; Beninati, S; Jakus, J; Nicolini, L; Passeggio, A | 1 |
| Akeo, K; Kudoh, J; Mashima, Y; Oguchi, Y; Saga, M; Shimizu, N | 1 |
| Gross, KL; Prior, RL | 1 |
| Faraone-Mennella, MR; Farina, B | 1 |
| Lory, S; Lu, HM; Mizushima, S | 1 |
| Galliano, M; Giagnoni, P; Iadarola, P; Madison, J; Minchiotti, L; Putnam, FW; Stoppini, M; Watkins, S | 1 |
| Abdul Jabbar, M; Kasturi, S; Sen, GC; Sen, I | 1 |
| Erijman, L; Lorimer, GH; Paladini, AA; Weber, G | 1 |
| Canters, GW; Ubbink, M | 1 |
| Aubourg, P; Cartier, N; Douar, AM; Mandel, JL; Mosser, J; Sarde, CO | 1 |
| Blouquit, Y; Fucharoen, S; Galacteros, F; Pravatmuang, P; Rosa, J; Srisomsap, C; Surarit, R; Svasti, J; Wasi, P | 1 |
| Capoor, AK; Ramana, D; Sashidhar, RB | 1 |
| Allen, KN; Carlson, SC; Farber, GK; Gerrity, DP; Glasfeld, A; Lavie, A; Petsko, GA; Ringe, D; Tanada, TN | 1 |
| Allende, CC; Allende, JE; Gatica, M; Jedlicki, A | 1 |
| Esmon, CT; Mather, T; Rezaie, AR; Sussman, F | 1 |
| Vergères, G; Waskell, L; Wu, FF | 1 |
| Barth, ML; Fensom, A; Harris, A | 1 |
| de Prat Gay, G; Fersht, AR; Johnson, CM | 1 |
| Kanno, T; Kobayashi, A; Li, SS; Maekawa, M; Sudo, K; Sugiyama, E | 1 |
| Giaume, C; Peusner, KD | 1 |
| Adachi, K; Harada, H; Kimura, A; Koga, Y; Nishi, H; Sasazuki, T; Toshima, H | 1 |
| Cunningham, SJ; Farrés, J; Takahashi, K; Wang, TT; Wang, X; Weiner, H | 1 |
| Escobar, WA; Fink, AL; Lewis, ER; Tan, AK | 1 |
| Bartolone, L; Benvenga, S; Filetti, S; Pontecorvi, A; Regalbuto, C; Trimarchi, F | 1 |
| Gallardo, D; Ribera, A; Simsek, S; von dem Borne, AE | 1 |
| Cody, CW; Huang, PC | 1 |
| Baskova, IP; Kuzina, EV; Zavalova, LL | 1 |
| Alvarsson, M; Efendic, S; Glaser, A; Grill, V; Luthman, H; Wajngot, A | 1 |
| Bustin, M; Friedman, FK; Lehn, DA; Postnikov, YV; Robinson, RC; Shiloach, J | 1 |
| Andresen, BS; Bolund, L; Hansen, AB; Hansen, PS; Jensen, HK; Jensen, LG; Jensen, TG; Kjeldsen, M; Meinertz, H; Nielsen, V | 1 |
| Horovitz, A; Kovalenko, O; Yifrach, O | 1 |
| Fisher, HF; Maniscalco, SJ; Singh, N | 1 |
| Sharrocks, AD; Shaw, PE; von Hesler, F | 1 |
| Liao, M; Lusty, CJ | 1 |
| Blanchard, L; Karst, F | 1 |
| Sternlicht, H; Szasz, J; Yaffe, MB | 1 |
| Eklund, H; Fuchs, JA; Gleason, FK; Nikkola, M | 1 |
| Bosch, D; Struyvé, M; Tommassen, J; Visser, J | 1 |
| Birnbaum, S; Britten, ML; Hixson, JE; Kammerer, CM; Mott, GE; Powers, PK; VandeBerg, JL | 1 |
| Anglés-Cano, E; Fleury, V; Lijnen, HR | 1 |
| Hwang, PP; Lee, JI; Wilson, TH | 1 |
| Andresen, BS; Bolund, L; Bross, P; Ghisla, S; Gregersen, N; Jensen, TG; Kräutle, F; Kølvraa, S; Nandy, A; Winter, V | 1 |
| Imajo, S; Ishiguro, M; Nukaga, M; Sawai, T; Tanimoto, K; Tsukamoto, K | 1 |
| Huang, J; Puett, D | 1 |
| Friedman, JM; Hirsch, RE; Huang, S; Lin, MJ; Nagel, RL; Vidugiris, GJ; Vidugirus, GV | 1 |
| Eiden, MV; Farrell, KB; Wilson, CA | 1 |
| Fisher, HF; Maniscalco, SJ; Saha, SK; Vicedomine, P | 1 |
| Hodges, RS; Monera, OD; Privalov, PL; Yu, Y | 1 |
| Csiszar, K; Kagan, HM; Narasimhan, N; Reddy, VB | 1 |
| Liebert, F | 1 |
| Hodges, RS; Kay, CM; Lavigne, P; Sönnichsen, FD | 1 |
| Rao, VS; Seshadri, K; Vishveshwara, S | 1 |
| Chao, HG; Fairman, R; Lavoie, TB; Matsueda, GR; Novotny, J; Villafranca, JJ | 1 |
| Guo, Q; Krieger, M; Penman, M; Trigatti, BL | 1 |
| Anders, J; Mense, M; Schlegel, R; Sparkowski, J | 1 |
| Castillo-Olivares, JL; Escudero, C; Fernández, P; García-Páez, JM; Jorge-Herrero, E | 1 |
| Eggeling, L; Krämer, R; Kronemeyer, W; Sahm, H; Vrljic, M | 1 |
| Fujiwara, K; Motokawa, Y; Okamura-Ikeda, K | 1 |
| Aurelian, L; Kulka, M; Nelson, JW; Smith, CC; Zhu, J | 1 |
| Coleman, CS; Huang, H; Pegg, AE | 1 |
| Hancock, RE; Sukhan, A | 1 |
| Chang, SL; Chiang, CM; Lin, HJ; Wu, WG | 1 |
| Nakao, T; Ogura, M; Okada, T; Takahashi, H | 1 |
| Eritja, R; Schliebs, W; Thanki, N; Wierenga, R | 1 |
| Cheng, CC; Egashira, Y; Manabe, A; Ohta, T; Sanada, H | 1 |
| Bucossi, G; Eismann, E; Kaupp, UB; Nizzari, M; Seri, M; Sesti, F; Torre, V | 1 |
| Delgado, AV; Gallardo, V; Gonzalez-Caballero, F; Ruiz, MA; Vera, P | 1 |
| Chacko, S; Wang, Z | 1 |
| Akar, E; Akar, N; Cin, S; Taştan, H | 1 |
| Czaplinski, K; Peltz, SW; Weng, Y | 1 |
| Bouchard, C; Després, JP; Dionne, FT; Lupien, PJ; Moorjani, S; Nadeau, A; Prud'homme, D; Tchernof, A; Vohl, MC | 1 |
| Rykke, M; Skjørland, KK; Sønju, T | 1 |
| Izzarelli, DG; Lewis-Higgins, L; Palmer, D; Parker, EM; Shapiro, RA | 1 |
| Hwa, J; Perez, DM; Porter, JE | 1 |
| Arnaud, P; Lowe, CR; Murray, JA; Squirrell, DJ; White, PJ | 1 |
| Kane, KP; Potter, TA; Shen, L | 1 |
| Chevallier, J; Haguenauer-Tsapis, R; Pinson, B; Urban-Grimal, D | 1 |
| Jafri, S; Stauffer, GV; Urbanowski, ML | 1 |
| Hesketh, A; Kawamoto, S; Ochi, K; Okamoto, S; Shima, J | 1 |
| Hann, M; Kanebayashi, Y; Nakao, T; Ogura, M; Okada, T; Shino, T; Takahashi, H | 1 |
| Esaki, N; Hong, SP; Kim, HS; Ro, HS; Seo, HJ; Soda, K; Sung, MH; Yoshimura, T | 1 |
| Hayashi-Iwasaki, Y; Oshima, T; Yaoi, T | 1 |
| Bahinski, A; Mikala, G; Schwartz, A; Tang, S; Yamamoto, S; Yatani, A | 1 |
| Fitzgerald, LM; Szmant, AM | 1 |
| Chen, EC; Cheng, XF; Lorand, L; Parameswaran, KN; Velasco, PT; Wilson, JH | 1 |
| Kovacs, H; Mark, AE; van Gunsteren, WF | 1 |
| Chung, HO; Kato, T; Kato, Y; Tomizawa, K; Wakabayashi, K | 1 |
| Alexander, P; Antosiewicz, J; Bryan, P; Gilson, M; Khare, D; Orban, J | 1 |
| Cosgriff, AJ; Pittard, AJ | 1 |
| Halford, SE; Hancox, EL | 1 |
| Abdel-Ghany, AG; Bross, P; Engst, S; Ghisla, S; Gregersen, N; Kieweg, V; Kräutle, FG; Nandy, A; Rasched, I; Strauss, A; Vock, P | 1 |
| Oettmeier, W; Rutherford, WA; Sopp, G | 1 |
| Ni, L; Sheikh, S; Weiner, H | 1 |
| Reade, RD; Robbins, MA; Rochon, DM | 1 |
| Krieg, T; Labrèze, C; Langbein, L; Leigh, IM; Rogers, MA; Roul, S; Schweizer, J; Stevens, HP; Taieb, A; Winter, H | 1 |
| Krämer, R; Lambert, C; Peter, H; Ruffert, S; Wendisch, VF | 1 |
| Feng, S; Jang, JH; Kan, M; McKeehan, K; McKeehan, WL; Wang, F | 1 |
| Fless, GM; Furbee, J; Meredith, SC; Santiago, JY | 1 |
| Kim, U; McCormick, DA; Sanchez-Vives, MV | 1 |
| Davidson, VL; Graichen, ME; Hosler, JP; Jones, LH; Mathews, FS | 1 |
| Ishioka, N; Kogure, T; Kurosu, Y | 1 |
| Binder, BR; Ecke, S; Geiger, M | 1 |
| Ha, JH; Hellman, U; Johnson, ER; Li, L; McKay, DB; Sousa, MC; Takeda, S; Wernstedt, C; Wilbanks, SM | 1 |
| Corrigan, A; Craig, AG; Gulyas, J; Koerber, SC; Lahrichi, SL; Miranda, A; Rivier, C; Rivier, J; Vale, W | 1 |
| Grünschlag, CR; Haas, HL; Stevens, DR | 1 |
| Boddy, MN; Borden, KL; Duprez, E; Freemont, PS | 1 |
| Aghajanian, S; Engel, PC; Goyal, A; Hayden, BM; Wang, XG | 1 |
| Glanville, RW; Qian, RQ | 1 |
| Blostein, R; Daly, SE; Lane, LK | 1 |
| Chitnis, PR; Chitnis, VP; Ke, A | 1 |
| Laughlin, LT; Reed, GH | 1 |
| Kajita, M; Miyazaki, T; Mizutani, N; Murata, Y; Niwa, T; Ohmori, S; Seo, H | 1 |
| Arkhipova, SF; Artem'ev, IV; Ivanov, VT; Kostetskiĭ, PV; Rodionov, IL; Rodionova, LN | 1 |
| Brown, WT; Ju, W; Kaczmarski, AL; Kaczmarski, W; Liu, B; Mclendon, L; Sklower Brooks, SS; Wisniewski, KE; Xu, WM; Xu, WW; Zhong, N | 1 |
| Conner, R; Fairbanks, VF; Hoyer, JD; Thibodeau, SN; Viker, KA; Wick, MJ | 1 |
| Hassan, F; Hayden, M; Henderson, H; Leisegang, F; Marais, D | 1 |
| Endo, K; Esaki, N; Fuchikami, Y; Kishimoto, K; Liu, L; Manning, JM; Soda, K; Yoshimura, T | 1 |
| Bjork, NS; Deveney, J; Moorhouse, KG; Mulkerrin, MG; Nashabeh, W; Ryskamp, T | 1 |
| Bakillah, A; Hussain, MM; Jamil, H | 1 |
| Cone, RD; Lu, D; Vage, DI | 1 |
| Chang, S; Hsieh, T; Hu, T | 1 |
| Kamm, RD; Lauffenburger, DA; Leon, EJ; Verma, N; Zhang, S | 1 |
| Hausinger, RP; Karplus, PA; Michel, LO; Pearson, MA; Schaller, RA | 1 |
| Eisenberg, E; Greene, L; Rajapandi, T; Wu, C | 1 |
| Debinski, W; Gibo, DM; Kealiher, A; Obiri, NI; Puri, RK | 1 |
| Hara, H; Kaji, A | 1 |
| Cai, LQ; Defillo-Ricart, M; Herrera, C; Imperato-McGinley, J; Katz, MD; Stavrou, SS; Zhu, YS | 1 |
| Binderup, K; Preiss, J | 1 |
| Cederholm-Williams, SA; Cockell, CS; Dawson, KM; Marshall, JM; Ponting, CP | 1 |
| Crnogorac, MM; Ejdebäck, M; Hansson, O; Ivković-Jensen, MM; Kostić, NM; Ullmann, GM; Young, S | 1 |
| Chapalain, V; Labrèze, C; Mercier, M; Rogers, MA; Schweizer, J; Surlève-Bazeille, JE; Taieb, A; Winter, H | 1 |
| Assaraf, YG; Goldman, ID; Zhao, R | 1 |
| Finazzi, G; Joliot, P; Wollman, FA; Zito, F | 1 |
| Lam, JT; Loo, DD; Panayotova-Heiermann, M; Wright, EM | 1 |
| Isralewitz, B; Krammer, A; Lu, H; Schulten, K; Vogel, V | 1 |
| Grahn, S; Hedstrom, L; Hofmann, HJ; Jakubke, HD; Kurth, T; Thormann, M; Ullmann, D | 1 |
| Matsuura, K; Miki, K; Nagashima, KV; Osyczka, A; Shimada, K; Sogabe, S; Yoshida, M | 1 |
| French, G; Granzier, H; Greaser, M; Trombitás, K | 1 |
| Centner, T; Jockusch, H; Kolmerer, B; Labeit, D; Labeit, S; Millevoi, S; Morell, J; Olivieri, N; Pastore, A; Witt, CC | 1 |
| De Meester, I; Harvey, DJ; Opdenakker, G; Polfliet, M; Proost, P; Struyf, S; Van Aelst, I; Van Coillie, E; Van Damme, J | 1 |
| Rezaie, AR | 1 |
| Ghisla, S; Kieweg, V; Mancini-Samuelson, GJ; Sabaj, KM; Stankovich, MT | 1 |
| Agar, NS; Kuchel, PW; Ogawa, E | 1 |
| Brooks, HB; O'Leary, MH; Osterman, AL; Phillips, MA; Swanson, T | 1 |
| David, O; De Paola, M; Ivaldi, G; Rabino-Massa, E; Ricco, G; Scimè-Degani, V | 1 |
| Hodges, RS; Kay, CM; Kohn, WD | 1 |
| Choi, GS; Jung, SY; Kang, HJ; Lee, ES; Park, KB; Steinert, PM; Yang, JM; Yoneda, K | 1 |
| Munagala, NR; Wang, CC | 1 |
| Evans, JN; Helms, GL; Jakeman, DL; Pohl, ME; Shuttleworth, WA | 1 |
| Burgess, BK; Jung, YS; Roberts, VA; Stout, CD | 1 |
| Bizouarn, T; Fjellström, O; Hu, X; Rydström, J; Zhang, J | 1 |
| Andreev, OA; Borejdo, J; Lowey, S; Saraswat, LD; Slaughter, C | 1 |
| Matsuura, K; Nagashima, KV; Osyczka, A; Shimada, K | 1 |
| Anderson, WF; Lukas, TJ; Mirzoeva, S; Shuvalova, L; Watterson, DM; Weigand, S | 1 |
| Overman, SA; Thomas, GJ | 1 |
| Sun, S; Toney, MD | 1 |
| Hashimoto, K; Kikuchi, A; Shirouzu, M; Yokoyama, S | 1 |
| Chen, CP; Chern, SR; Jeng, CJ; Wang, KL; Wang, TY; Wang, W | 1 |
| Hong, YS; Korotchkina, LG; Liu, TC; Patel, MS; Vettakkorumakankav, NN | 1 |
| Ben-Ari, Y; Bernard, C; Esclapez, M; Hirsch, JC | 1 |
| Dingjan, GM; Grosveld, F; Hendriks, RW; Maas, A | 1 |
| Azuma, M; Batanero, E; Kiyono, H; Kweon, MN; McGhee, JR; Otake, S; Takeda, Y; Yamamoto, M; Yamamoto, S | 1 |
| Amin, A; Archambault, J; Brault, K; Cordingley, MG; Pelletier, A; Sauvé, F; Titolo, S; Wardrop, E; White, PW | 1 |
| Bigotti, MG; Brunori, M; Cutruzzolà, F; Staniforth, RA; Travaglini-Allocatelli, C | 1 |
| Clarke, DT; Doig, AJ; Jones, GR; Stapley, BJ | 1 |
| Day, S; Dunn, PP; Fuggle, SV; Lewis, L; Makar, Y; Morrell, G; Ross, J; Stewart, A; Whalley, J | 1 |
| Scheiner-Bobis, G; Schreiber, S | 1 |
| Buse, G; Hellwig, P; Mäntele, W; Soulimane, T | 1 |
| Bautsch, W; Cain, SA; Crass, T; Monk, PN; Pease, JE | 1 |
| Just, L; Meyer, DK; Olenik, C | 1 |
| Arninkhof, MJ; Kersten, MA; Op den Camp, HJ; van der Drift, C; Van Griensven, LJ | 1 |
| Mine, Y; Zhang, JW | 1 |
| Maeda, S; Nagasaka, T; Onaya, T; Shindo, K; Shiozawa, Z; Tawata, M; Togashi, S; Watanabe, H | 1 |
| Kultje, C; Sawase, T; Wennerberg, A | 1 |
| Feng, B; Stemmer, PM | 1 |
| Almeida, A; Bolaños, JP; Heales, SJ; Medina, JM; Vega-Agapito, V | 1 |
| Dammerman, RS; Flint, AC; Kriegstein, AR | 1 |
| Abildgaard, F; Chae, YK; Markley, JL; Royer, CA | 1 |
| Blomlöf, J; Cederlund, A; Lindskog, S | 2 |
| Anderson, RA; Burden, LM; Doughman, SD; Ghirlando, R; Hurley, JH; Murray, D; Rao, VD | 1 |
| Kosa, JL; Sweasy, JB | 1 |
| Ibarra-Molero, B; Loladze, VV; Makhatadze, GI; Sanchez-Ruiz, JM | 1 |
| Bertolini, S; Calandra, S; Cortese, C; Federici, G; Liberatoscioli, L; Motti, C; Rampa, P; Trovatello, G | 1 |
| Lee, JC; Yeh, LC | 1 |
| Harris, TK; Massiah, MA; Mildvan, AS; Wu, G | 1 |
| Austin, CA; Marshall, R; Meczes, EL; Thorn, R; Turnbull, RM; West, KL | 1 |
| Corzo, N; del Castillo, MD; Olano, A; Sanz, ML | 1 |
| Cartailler, JP; Haigler, HT; Luecke, H | 1 |
| Blacklow, SC; North, CL | 1 |
| Banerjee, A; Kidd, EA; Watson, TF | 1 |
| Mark, M; Reinhart, WH; Walter, R | 1 |
| Huang, X; Raushel, FM | 1 |
| Boudaba, C; Daftary, SS; Tasker, JG | 1 |
| Imoto, T; Ishibashi, R; Masumoto, K; So, T; Ueda, T | 1 |
| Attane, F; Beaudry, P; Besson, G; Delasnerie-Lauprêtre, N; Hannequin, D; Laplanche, JL; Manivet, P; Peoc'h, K | 1 |
| Bartell, SM; Faustman, EM; Omenn, GS; Ponce, RA; Takaro, TK; Zerbe, RO | 1 |
| Hinchliffe, SJ; Morgan, BP | 1 |
| Hannig, M | 1 |
| Jeltsch, A; Lanio, T; Pingoud, A | 1 |
| Ando, S; Tadano, J; Takasaki, Y; Tang, D | 1 |
| Bergles, DE; Jahr, CE; Roberts, JD; Somogyi, P | 1 |
| Busby, SJ; Rhodius, VA | 1 |
| Bailey, AJ; de Mari, M; Hickman, D; Koopmans, M; Miles, CA; Sims, TJ | 1 |
| Hayashi, Y; Kitamoto, N; Kitamoto, T; Kutomi, T; Muramoto, T; Sano, C; Tanaka, T; Yutani, C | 1 |
| Augustine, GJ; Pettit, DL | 1 |
| Ilonen, J; Laine, AP; Nejentsev, S; Simell, O | 1 |
| Heise, CT; Leamy, CE; Nicholls, JR; Wallis, R | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Doi, H; Itoh, K; Ozand, PT; Sakuraba, H; Shimmoto, M; Takiguchi, K | 1 |
| Brennan, RG; Goodman, RH; Schumacher, MA | 1 |
| Beeley, JA; Stevenson, AG; Yip, HK | 2 |
| Fujii, Y; Furuichi, M; Nakabeppu, Y; Sekiguchi, M; Shimokawa, H | 1 |
| Bujons, J; Hoffman, BM; Leesch, VW; Mauk, AG | 1 |
| Bella, J; Berman, HM; Brodsky, B; Kramer, RZ; Mayville, P; Venugopal, MG | 1 |
| Nakamoto, RK; Peskova, YB | 1 |
| Weiner, H; Zhou, J | 1 |
| Haak, R; Noack, MJ; Wicht, MJ | 1 |
| Bossi, D; Colombo, S; Gorwa, MF; Lemaire, K; Loïez, A; Ma, P; Thevelein, JM; Van Dijck, P; Versele, M | 1 |
| Brodie, TB; Faro, M; Gómez-Moreno, C; Hazzard, JT; Hurley, JK; Medina, M; Tollin, G | 1 |
| Bock, PE; Boxrud, PD | 1 |
| Davies, PL; Elce, JS; Hosfield, CM; Jia, Z; Moldoveanu, T | 1 |
| Haas, OA; Muhr, D; Niederle, B; Scheuba, C; Schlegl, R; Vierhapper, H; Wagner, T; Weinhaeusel, A | 1 |
| Darden, TA; Gorokhov, A; Negishi, M; Pedersen, LC; Pedersen, LG; Perera, L | 1 |
| Maeshima, M; Nakanishi, Y; Saijo, T; Wada, Y | 1 |
| Berg, K; Darin, N; Kyllerman, M; Martinsson, T; Oldfors, A; Tajsharghi, H; Wahlstrom, J | 1 |
| Benjamin, DC; Gudmundsdóttir, A; Kristjánsdóttir, S | 1 |
| Berg, LJ; Ching, KA; Tsoukas, CD; Yang, WC | 1 |
| Bartleson, C; Biorn, AC; Graves, DJ | 2 |
| Kraynov, VS; Liu, J; Showalter, AK; Tsai, MD; Zhong, X | 1 |
| Blanchard, JS; Zheng, R | 1 |
| Altieri, PI; Escobales, N; Rivera-Correa, M; Rodriguez, JF | 1 |
| Bräuner-Osborne, H; Jensen, AA; Jensen, LB; O'Hara, PJ; Sheppard, PO | 1 |
| Alape-Girón, A; Basak, AK; Carr, FJ; Carter, G; Flores-Díaz, M; Holley, J; Keyte, M; Miller, J; Moss, DS; Naylor, CE; Thelestam, M; Titball, RW; Walker, N | 1 |
| Pielak, GJ; Wang, X | 1 |
| Damjanovich, S; Gáspár, R; Hajdu, P; Horjales, E; Panyi, G; Péter, M; Possani, LD; Varga, Z | 1 |
| Gazzano-Santoro, H; Idusogie, EE; Mulkerrin, MG; Presta, LG; Totpal, K; Ultsch, M; Wong, PY | 1 |
| Aertsen, A; Balzarini, J; Camarasa, MJ; De Clercq, E; Pelemans, H; Pérez-Pérez, MJ; San-Félix, A; Van Laethem, K; Vandamme, AM; Velázquez, S | 1 |
| Arruda, P; Langone, F; Papes, F; Surpili, MJ; Trigo, JR | 1 |
| Arza, B; Collen, D; De Maeyer, M; Félez, J; Lijnen, HR | 1 |
| Azeva, TN; Gilep, AA; Lepesheva, GI; Strushkevich, NV; Usanov, SA | 1 |
| Homma, H; Imai, K; Kamo, N; Lee, JA; Long, Z; Maruyama, T; Nimura, N; Okamoto, T; Oshima, T; Sekine, M; Sumi, M; Yamagishi, A; Yohda, M | 1 |
| Komori, S; Koyama, K; Matsumoto, F; Matsumoto, H; Nakae, K; Okada, Y; Onishi, Y; Sakata, K; Sawai, H; Shima, H; Yoshida, O | 1 |
| Fukuda, K; Liu, MH; Nakahara, H; Shibasaki, Y | 1 |
| Hwang, JJ; Stupp, SI | 1 |
| Hassall, DC; Morrow, LA; Watts, DC; Wilson, NH | 1 |
| Gentry, LR; Sticker, LS; Thompson, DL | 1 |
| Heinzle, E; Wittmann, C | 1 |
| Antignani, A; Cubellis, MV; D'Alessio, G; Naddeo, M; Russo, A | 1 |
| Francky, A; Francky, BM; Gruden, K; Kregar, I; Krizaj, I; Pain, RH; Pungercar, J; Ritonja, A; Strukelj, B | 1 |
| Fontecave, M; Houée-Levin, C; Lombard, M; Nivière, V; Touati, D | 1 |
| Hempel, J; Kuo, I; Lindahl, R; Perozich, J | 1 |
| Goto, G; Hosoya, Y; Kawashita, Y; Marshall, GW | 1 |
| Gakiere, B; Galili, G; Tang, G; Zhu, X | 1 |
| Biorn, AC; Graves, DJ | 1 |
| Canto, P; de la Chesnaye, E; Méndez, JP; Söderlund, D; Ulloa-Aguirre, A | 1 |
| Eikmanns, BJ; Katsoulidis, E; Möckel, B; Peters-Wendisch, PG; Sahm, H; Schiel, B; Wendisch, VF | 1 |
| Bergqvist, S; Ladbury, JE; O'Brien, R | 1 |
| Cho, N; Kötter, R; Luhmann, HJ; Schubert, D; Staiger, JF; Zilles, K | 1 |
| Fairman, R; Robblee, J; Vu, C; Werner, KM | 1 |
| Ennis, IL; French, RJ; Li, RA; Marbán, E; Tomaselli, GF | 1 |
| Han, H; Liu, G; Shangguan, D; Zhao, R; Zhao, Y | 1 |
| Grimsley, GR; Makarov, AA; Pace, CN; Shaw, KL; Yakovlev, GI | 1 |
| Liu, Y; Schepartz, A | 1 |
| Amicosante, M; Arroyo, J; Berretta, F; Colizzi, V; Lechler, R; Lombardi, G; Saltini, C; Sanarico, N | 1 |
| Jezierski, G; Pasenkiewicz-Gierula, M | 1 |
| Hossain, M; Kinoshita, JI; Matsumoto, K; Nakamura, Y; Suzuki, N; Yamada, Y | 1 |
| Bangera, MG; McGuire, KA; Olsen, JG; Siggaard-Andersen, M; von Wettstein-Knowles, P | 1 |
| Bongenhielm, U; Young, C | 1 |
| Dammaschk, T; Kaup, M; Mokrys, K; Ott, KH; Stratmann, U | 1 |
| Ahuja, N; Bhatnagar, R; Kumar, P | 1 |
| Dijkhuizen, L; Dijkstra, BW; Kralj, S; Leemhuis, H; Uitdehaag, JC; van der Veen, BA | 1 |
| Bijnens, AP; Brouwers, E; Declerck, PJ; Gils, A; Knockaert, I; Komissarov, AA; Shore, JD; Stassen, JM | 1 |
| Dickerson, IM; Krajewski, JL; Potter, LT | 1 |
| Dangel, P; Eikmanns, BJ; Möckel, B; Petersen, S; Riedel, C; Rittmann, D; Sahm, H | 1 |
| Hahn, P; Hellwig, E; Maragakis, GM | 1 |
| Hossain, M; Kawanaka, T; Kinoshita, J; Matsumoto, K; Yamada, Y | 1 |
| Ida, K; Matsuura, T; Norioka, S; Sakai, H; Sakiyama, F; Sato, M; Unno, M | 1 |
| Hegde, AM; Munshi, AK; Shetty, PK | 1 |
| Anders, MW; Blackburn, AC; Board, PG; Coggan, M; Lantum, H; Parker, MW; Polekhina, G; Tzeng, HF | 1 |
| Mitra, R; Sainis, KB; Suseelan, KN | 1 |
| Ferkey, DM; Graham, TA; Kimelman, D; Mao, F; Xu, W | 1 |
| Inoue, T; Kirino, Y; Shimozono, S; Watanabe, S | 1 |
| Dammaschke, T; Kaup, M; Mokrys, K; Reiner Ott, KH; Stratmann, U | 1 |
| Hampson, DR; Naples, M; Peltekova, V; Rosemond, E; Thøgersen, H | 1 |
| Bozkurt, N; Isbir, T; Oztürk, O | 1 |
| Powers-Lee, SG; Saeed-Kothe, A | 1 |
| Bolbach, G; Jensen, TR; Kjaer, K; Lahav, M; Leiserowitz, L; Shavit, E; Tang, M; Weissbuch, I; Zepik, H | 2 |
| den Hartog, JA; Liskamp, RM; Rijkers, DT | 1 |
| Arvidsson, A; Sennerby, L; Stirling, C; Wennerberg, A | 1 |
| Gellissen, B; Rosin, M; Splieth, C | 1 |
| Loh, T; Marinus, MG; Wu, TH | 1 |
| Brosius, JL; Colman, RF | 1 |
| Fan, X; Haile, A; Levine, MA; Mullis, PE; Salvatori, R | 1 |
| Naumann, TA; Reznikoff, WS | 1 |
| Drouin, EE; Hansen, U; Schrader, CE; Stavnezer, J | 1 |
| Kiba, N; Koizumi, H; Miwa, T; Tachibana, M; Tani, K | 1 |
| Costagliola, S; Govaerts, C; Nubourgh, I; Pardo, L; Smits, G; Vassart, G | 1 |
| Kamoun, P; Rabier, D; Richard, V; Saudubray, JM | 1 |
| Arnon, S; Dolfin, T; Grinshpan, G; Ozono, K; Regev, R; Reish, O; Yamazaki, M | 1 |
| Fitch, CA; García-Moreno E, B; Karp, DA; Lattman, EE; Lee, KK; Stites, WE | 1 |
| Finazzi, G | 1 |
| Gale, AJ; Griffin, JH; Tsavaler, A | 1 |
| Kobayashi, J; Misawa, Y; Murano, T; Shinomiya, M; Shirai, K; Tashiro, J; Yoshida, T | 1 |
| Adams, A; De Kimpe, N; Demyttenaere, J; Kersiene, M; Obretenov, C; Tehrani, KA | 1 |
| Chowdhury, B; Cordella-Miele, E; Mantile-Selvaggi, G; Miele, L; Mukherjee, AB; Zhang, Z | 1 |
| Burrow, MF; Kubo, S; Sakoolnamarka, R; Tyas, MJ | 1 |
| Arvidsson, A; Milleding, P; Wennerberg, A | 1 |
| Berthomieu, C; Dupeyrat, F; Fontecave, M; Nivière, V; Verméglio, A | 1 |
| Ben-Ari, Y; Diabira, D; Gozlan, H; Hennou, S; Khalilov, I | 1 |
| Barnard, DC; Li, J; Patton, JG | 1 |
| Ayukarn, K; Changtrakun, Y; Fucharoen, G; Fucharoen, S; Sanchaisuriya, K; Siriratmanawong, N | 1 |
| Ananthnarayan, V; Horton, NC; Kohn, J; Lusetti, S; Martin, AM; Otey, C; Perona, JJ; Sam, MD | 1 |
| Brändén, M; Brzezinski, P; Gennis, RB; Tomson, F | 1 |
| Legler, PM; Massiah, MA; Mildvan, AS | 1 |
| Fritsche, A; Häring, H; Holzwarth, M; Machicao, F; Maerker, E; Stumvoll, M; Teigeler, A; Tschritter, O; Weisser, M | 1 |
| Bottger, P; Pedersen, L | 1 |
| Barnett, ME; Zolkiewski, M | 1 |
| Becerra, SP; Meyer, C; Notari, L | 1 |
| Hiasa, H | 1 |
| Azzam, T; Domb, AJ; Ehrenfreund-Kleinman, T; Gazit, D; Gazit, Z; Golenser, J | 1 |
| Crabtree, JW; Isaac, JT | 1 |
| Bossa, F; De Biase, D; John, RA; Tramonti, A | 1 |
| Chaudhury, K; Guha, SK; Jagannathan, NR; Sharma, U | 1 |
| Fairman, R; Horng, JC; Moroz, V; Raleigh, DP; Rigotti, DJ | 1 |
| Fu, TF; Kazanina, G; Scarsdale, JN; Schirch, V; Wright, HT | 1 |
| Arcari, P; Cantiello, P; De Paola, B; Fiengo, A; Masullo, M; Vitagliano, L; Zagari, A | 1 |
| Cachau, R; Cardemil, E; González-Nilo, FD; Krautwurst, H; Yévenes, A | 1 |
| Baudin-Creuza, V; Fablet, C; Friedman, JM; Hirsch, RE; Juszczak, LJ; Lesecq-Le Gall, S; Nagel, RL; Pagnier, J | 1 |
| Schmid, S; Weber, M | 1 |
| Ravelonandro, M; Yang, S | 1 |
| Amiraslanov, I; Chern, SS; Hsiao, YY; Leu, YJ; Liao, YD; Liaw, YC; Wang, SC | 1 |
| Berndt, KD; Chiaraluce, R; Consalvi, V; Ladenstein, R; Lebbink, JH | 1 |
| Conceição, LE; Dinis, MT; Grasdalen, H | 1 |
| Antosiewicz, JM; Briggs, JM; Bruix, M; Grimsley, GR; Huyghues-Despointes, BM; Laurents, DV; Newsom, S; Pace, CN; Rico, M; Schell, D; Scholtz, JM; Shaw, KL; Thurlkill, RL; Treviño, S | 1 |
| Baik, HS; Cho, HS; Choi, JW; Lee, SY; Paik, SY; Park, HS; Park, YC; Ra, KS; Yun, JW | 1 |
| Dang, BN; Fitch, CA; García-Moreno E, B; Schwehm, JM; Stites, WE | 1 |
| Gonzalez-Islas, C; Hablitz, JJ | 1 |
| Gardella, TJ; Khatri, A; Petroni, BD; Shimizu, N | 1 |
| Czirják, G; Enyedi, P | 1 |
| Laskowski, M; Markley, JL; Qasim, MA; Song, J | 1 |
| Bickers, DR; Christiano, AM; Djabali, K; Garzon, MC; Lalin, T; Longley, BJ; Panteleyev, AA; Zlotogorski, A | 1 |
| Galili, G; Zhu, X | 1 |
| Eisthen, HL; Park, D | 1 |
| Chaussain-Miller, C; Decup, F; Domejean-Orliaguet, S; Gillet, D; Guigand, M; Kaleka, R; Laboux, O; Lafont, J; Lasfargues, JJ; Medioni, E; Serfaty, R; Toumelin-Chemla, F; Tubiana, J | 1 |
| Beyth, N; Mass, A; Ziskind, D | 1 |
| Belay, G; Budka, H; Hainfellner, JA; Jarius, C; Kovacs, GG; Mitrova, E | 1 |
| Aldred, S; Fitzgerald, M; Moore, KM; Waring, RH | 1 |
| Kakaboura, A; Masouras, C; Staikou, O; Vougiouklakis, G | 1 |
| Andersen, JP; Clausen, JD | 2 |
| French, RJ; Henrikson, CA; Hui, K; Li, RA; Marbán, E; Sato, K; Tomaselli, GF | 1 |
| Harano, K; Harano, T; Hong, YF; Ohba, K; Suetsugu, Y; Than, AM | 1 |
| Malmendal, A; Meissner, A; Møller, JV; Nielsen, G; Nielsen, NC | 1 |
| Kennan, AJ; Schnarr, NA | 1 |
| Berti, PJ; Byczynski, B; Mizyed, S; Wright, JE | 1 |
| Al-Kilani, MG; Dummer, PM; Whitworth, JM | 1 |
| Ma, K; Wang, K | 1 |
| Jakobs, C; Roos, B; Struys, EA; Verhoeven, NM | 1 |
| Israel, JM; Le Masson, G; Poulain, DA; Theodosis, DT | 1 |
| Burkhard, P; Hodges, RS; Ivaninskii, S; Lee, DL | 1 |
| Dai, J; Haro, D; Marrero, PF; Napal, L; Treber, M; Woldegiorgis, G | 1 |
| Bennaars, A; Brautaset, T; Crabbe, E; Dillingham, RD; Flickinger, MC; Kaufmann, C; Williams, MD | 1 |
| Bosshard, HR; Marti, DN | 1 |
| Daiho, T; Danko, S; Iizuka, H; Suzuki, H; Wang, G; Yamasaki, K | 1 |
| Isa, T; Yamashita, T | 1 |
| Grove, A | 1 |
| Bertics, PJ; Denlinger, LC; Dubyak, GR; Fisette, PL; Gudipaty, L; Parker, K; Proctor, RA; Sommer, JA; Watters, JW | 1 |
| Akca, T; Cehreli, ZC; Ozgünaltay, G; Yazici, AR | 1 |
| Palzkill, T; Zhang, Z | 1 |
| Burrow, MF; Sakoolnamarka, R; Tyas, MJ | 1 |
| Araki, K; Kurosaki, N; Mataki, S; Tonami, K | 1 |
| Benkovic, SJ; Greasley, SE; Wall, MJ; Wilson, IA; Wolan, DW | 1 |
| BIGGER, LC; DAVIES, R; FOLKES, JP; GALE, EF | 1 |
| BALE, WF; MILLER, LL | 1 |
| HANKE, ME; KOPPELMAN, R; MANDELES, S | 1 |
| CAMERON, HS; MEYER, ME | 2 |
| QUINTO, G | 1 |
| BENCARERRAF, B; KANTOR, FS; OJEDA, A | 1 |
| CIRCO, R; FREEMAN, BA | 1 |
| FEREN, CJ; HEDRICK, LR | 1 |
| GERULAT, BF; MAURER, PH; PINCHUCK, P | 1 |
| CRAFT, MK; DEWALD, HA; NICOLAIDES, ED | 1 |
| OGUR, M; OGUR, S; ROSHANMANESH, A | 1 |
| Fisher, H; Leveille, GA | 1 |
| Chalisova, NI; Penniiaĭnen, VA | 1 |
| Eckel, J; Rakatzi, I; Seipke, G | 1 |
| Fujita, H; Funck, T; Granzier, H; Labeit, D; Labeit, S; Lahmers, S; Watanabe, K; Witt, C; Wu, Y | 1 |
| Bryksa, BC; Tanaka, T; Yada, RY | 1 |
| Dodson, ML; Lloyd, RS; Meador, MG; Rajagopalan, L | 1 |
| Baba, S; Matsushita, A; Nakamura, H; Nakano, K; Natsume, H; Nishiyama, K; Sasaki, S; Yamada, T | 1 |
| Aichinger, G; Amicosante, M; Arroyo, J; Berretta, F; Butler, RH; Colizzi, V; Diaz, G; Fraziano, M; Saltini, C; Sanarico, N; Wucherpfennig, KW | 1 |
| Blum, LJ; Degiuli, A; Marquette, CA | 1 |
| Kessler, H; Mann, E | 1 |
| Atílla, P; Müftüoglu, S; Ozgünaltay, G; Yazici, AR | 1 |
| Bokas, J; Burrow, MF; Tanumiharja, M; Tyas, MJ | 1 |
| Kimura, Y; Kinoshita, J; Matsumoto, K | 1 |
| Creamer, TP; Whittington, SJ | 1 |
| Feldmeyer, D; Lubke, J; Sakmann, B; Silver, RA | 1 |
| Fukuzawa, A; Kimura, S; Maruyama, K; Oshino, T; Shimamura, J | 1 |
| Boggs, JM; Hillar, A; Hodges, RS; Tripet, B; Wood, JM; Zoetewey, D | 1 |
| Björk, I; Bock, SC; Desai, UR; Olson, ST; Schedin-Weiss, S | 1 |
| Asso, M; Favaudon, V; Guigliarelli, B; Houée-Levin, C; Lombard, M; Nivière, V; Weill, CO | 1 |
| Schröder, JM; Sindern, E; Vorgerd, M; Züchner, S | 1 |
| Duke, NE; Londer, YY; Long, WC; Pokkuluri, PR; Schiffer, M | 1 |
| Czepas, J; Derewenda, U; Derewenda, ZS; Devedjiev, Y; Krowarsch, D; Otlewski, J | 1 |
| Agretti, P; Ceccarini, G; Chiellini, C; Chiovato, L; Lisi, S; Maffei, M; Mammoli, C; Marsili, A; Pelosini, C; Pinchera, A; Rosellini, V; Santini, F; Scartabelli, G; Tonacchera, M; Vitti, P | 1 |
| Allan, AB; Bell, GI; Bermano, G; Boodram, LL; Cockburn, BN; Docherty, K; Mahabir, D; Stein, R; Teelucksingh, S; Tsuchiya, T | 1 |
| Bailey, CJ; Flatt, PR; Gault, VA; Green, BD; Greer, B; Harriott, P; Irwin, N; Mooney, MH; O'Harte, FP | 1 |
| Elcock, AH; Thomas, AS | 1 |
| de Jong, AS; Glaudemans, DH; Melchers, WJ; van Kuppeveld, FJ; Willems, PH | 1 |
| Crawford, E; Hendzel, MJ; Lever, MA; Th'ng, JP | 1 |
| Anderson, ME; Bhansali, VS; Cundari, TR; Dinescu, A; Luo, JL | 1 |
| Allison, WS; Bandyopadhyay, S | 1 |
| Breaux, GA; Jarrold, MF; Kohtani, M; Sudha, R | 1 |
| Akçin, O; Aytepe, Z; Bilir, A; Sepet, E | 1 |
| Brendza, KM; Gatial, JE; Gilbert, SP; Hoenger, A; Klumpp, LM; Saxton, WM | 1 |
| Ballou, DP; Marsh, EN; Xia, L | 1 |
| Bulut, G; Bulut, H; Eronat, C; Zekioglu, O | 1 |
| Beyer, EC; Crye, M; Fenn, E; Gemel, J; Musa, H; Veenstra, RD | 1 |
| Almgren, P; Altshuler, D; Burtt, N; Daly, MJ; de Bakker, PI; Florez, JC; Gaudet, D; Groop, L; Hirschhorn, JN; Holmkvist, J; Hudson, TJ; Schaffner, SF; Tuomi, T | 1 |
| Benevides, JM; Bondre, P; Duda, RL; Hendrix, RW; Thomas, GJ | 1 |
| Chapman, RW; Cullen, SN; Jewell, DP; Li, JH; Yang, X | 1 |
| Miller, SM; Sha, L; Szurszewski, JH | 1 |
| Islam, MN; Kondo, H; Sueda, S; Yong-Biao, J | 1 |
| Diez-Gonzalez, F; Karaibrahimoglu, Y | 1 |
| Azrak, B; Callaway, A; Grundheber, A; Stender, E; Willershausen, B | 1 |
| Ahn Jo, S; Carp, RI; Jang, MK; Jeong, BH; Ju, YR; Kim, YS; Lee, HD; Lee, KH; Lee, YJ; Nam, JH; Park, KY | 1 |
| Carlberg, C; Frank, C; Lempiäinen, H; Matilainen, M; Molnár, F | 1 |
| Bulychev, A; Golemi-Kotra, D; Kim, C; Meroueh, SO; Mobashery, S; Stemmler, AJ; Stemmler, TL; Vakulenko, SB | 1 |
| Cole, SP; Conseil, G; Deeley, RG; Haimeur, A | 1 |
| Eramian, D; Liu, B; Mierke, D; Polgar, P; Taylor, L; Yu, J | 1 |
| Higuchi, S; Kamakura, K; Masaki, T; Matsushita, S; Mochizuki, H; Yokoyama, A | 1 |
| Bräuner-Osborne, H; Greenwood, JR; Hermit, MB | 1 |
| Alvarado, MV; Busse, A; León, P; Monterroso, V; Sánchez, MA | 1 |
| Schmid, FX; Sterner, R | 1 |
| Fure, S; Lingström, P | 2 |
| Escovar-Kousen, J; Irwin, DC; Wilson, DB; Zhou, W | 1 |
| Yang, YC; Zheng, G | 1 |
| Chen, XL; Ding, JP; Guo, LT; Jia, J; Jin, YX; Yu, YD | 1 |
| Casanova, M; Galán, A; Gow, NAR; MacCallum, DM; Martínez, JP; Murgui, A; Odds, FC | 1 |
| Delemarre-van de Waal, HA; Kemper, HC; Koper, JW; Lamberts, SW; te Velde, SJ; van Rossum, EF; Voorhoeve, PG | 1 |
| Clarkson, J; Shu, JC; Yudkin, MD | 1 |
| Bohrer, D; de Carvalho, LM; do Nascimento, PC; Mendonça, JK; Polli, VG | 1 |
| Kwak, EJ; Lim, SI | 1 |
| Austin, CA; Lakey, JH; Leontiou, C | 1 |
| Dudley, SC; Fozzard, HA; Glaaser, I; Hilber, K; Sandtner, W; Szendroedi, J; Todt, H; Zarrabi, T; Zebedin, E | 1 |
| Bartholomew, LA; Gimi, K; Senior, AE; Tombline, G; Tyndall, GA; Urbatsch, IL | 1 |
| Arvai, AS; Dodson, ML; Hitomi, K; House, PG; Kurtz, AJ; Lloyd, RS; Manuel, RC; McCullough, AK; Tainer, JA | 1 |
| Darin, N; Kyllerman, M; Ohlsson, M; Oldfors, A; Tajsharghi, H | 1 |
| Cato, MJ; Toney, GM | 1 |
| Ciani, B; Jourdan, M; Searle, MS | 1 |
| Arvidsson, A; Ortengren, U; Wennerberg, A | 1 |
| Gowrishankar, J; Laishram, RS; Nandineni, MR | 1 |
| Collet, H; Commeyras, A; Giani, O; Schué, F; Vayaboury, W | 1 |
| Hancock, MA; Koschinsky, ML; Spencer, CA | 1 |
| Chakrabarti, A; Chakrabarty, A; Chakrabarty, SB; Choudhury, D; Dasgupta, J; Datta, P; Dattagupta, JK; Sen, U | 1 |
| Akerman, KE; Kukkonen, A; Näsman, J; Peräkylä, M | 1 |
| Andresen, BS; Bross, P; Corydon, TJ; Engel, PC; Frazier, DM; Gregersen, N; Hansen, J; Kenney, JM; McCandless, SE; O'Reilly, L; Olpin, SE; Winter, V | 1 |
| Achilli, A; Barbiroli, B; Barboni, P; Baruzzi, A; Bucchi, L; Carelli, V; Dotti, M; Federico, A; Ghelli, A; Lodi, R; Lugaresi, A; Rengo, C; Torroni, A; Valentino, ML | 1 |
| Chen, HY; Lima, S; Phillips, RS; Shim, D; Sundararaju, B; Tavakoli, K | 1 |
| Cheng, J; Hada, T; Hashimoto-Tamaoki, T; Inokuchi, T; Ka, T; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamamoto, A; Yamamoto, T | 1 |
| Ostrov, DA; Sandberg, EM; Sayeski, PP; VonDerLinden, D | 1 |
| Chen, L; Krejci, L; Lewis, LK; Resnick, MA; Roh, DH; Sung, P; Tomkinson, AE; Trujillo, KM; Van Komen, S | 1 |
| Baritussio, A; Beers, MF; Brasch, F; Morrison, L; Mulugeta, S; Ochs, M; Pettenazzo, A; Russo, SJ; Stevens, PA | 1 |
| Kanno, T; Nagata, T; Nishizaki, T; Tanaka, A; Yaguchi, T; Yamamoto, S | 1 |
| Ballou, DP; Entsch, B; Ortiz-Maldonado, M | 1 |
| Amzel, LM; Azurmendi, HF; Bianchet, MA; Gabelli, SB; Kang, LW; Legler, PM; Massiah, MA; Mildvan, AS; Saraswat, V; Xia, Z | 1 |
| Fisher, PA; McConnell, M; Miller, H; Moutsiakis, DL; Mozzherin, DJ | 1 |
| Feng, L; Sheppard, K; Söll, D; Tumbula-Hansen, D | 1 |
| Axelsen, PH; Englander, SW; Giasson, BI; Graves, CL; Greenbaum, EA; Lupoli, MA; Lynch, DR; Mishizen-Eberz, AJ | 1 |
| Albrecht, J; Hertz, L; Hilgier, W; Schousboe, A; Sonnewald, U; Waagepetersen, HS; Ziemińska, E | 1 |
| Guan, Z; McClerren, AL; Raetz, CR; Rudolph, J; Zhou, P | 1 |
| Behanna, HA; Donners, JJ; Gordon, AC; Stupp, SI | 1 |
| Shuman, S; Zhu, H | 1 |
| Agmon, N | 1 |
| Brodsky, B; Kirkpatrick, A; Persikov, AV; Ramshaw, JA | 1 |
| Flückiger, L; Lussi, A; Stich, H; Waltimo, T | 1 |
| Isaacs, SN; Katragadda, M; Lambris, JD; Morikis, D; Sfyroera, G | 1 |
| Carmeliet, E; Carmeliet, P; Collen, D; Devriendt, K; Gewillig, M; Heidbüchel, H; Jongbloed, RJ; Mubagwa, K; Rossenbacker, T; Vereecke, J | 1 |
| Armengaud, J; Dedieu, A; Pellequer, JL; Quemeneur, E; Solques, O | 1 |
| Beyth, N; Kupietzky, A; Ziskind, D | 1 |
| Bouchard, JP; Brais, B; Dicaire, MJ; Duquette, A; Gosselin, I; Labuda, D; Loisel, L; Marchand, L; Mathieu, J; McNabb-Baltar, J; Roddier, K; St-Denis, A | 1 |
| Grabocka, E; Wedegaertner, PB | 1 |
| Grewer, C; Tao, Z | 1 |
| Dalal, S; Starcevic, D; Sweasy, J | 1 |
| Arceci, M; Bozzoni, I; Caffarelli, E; Dlakic, M; Gioia, U; Laneve, P | 1 |
| Guillén, N; Mounier, J; Prevost, MC; Seigneur, M | 1 |
| Berciano, J; Combarros, O; Fernández-Viadero, C; Infante, J; Llorca, J; Peña, N | 1 |
| Relyea, HA; Rimkus, S; van der Donk, WA; Wheatley, JL; Woodyer, R | 1 |
| Hosoya, Y; Marshall, GW; Shinkawa, H | 1 |
| Banerjee, A; Sherriff, M; Sonoda, H; Tagami, J; Watson, TF | 1 |
| Horiuchi, S; Kawaguchi, M; Kobayashi, M; Shibata, N | 1 |
| Gunner, MR; Kim, J; Mao, J | 1 |
| Aumas, C; de Roux, N; Gidenne, S; Haddad, F; Karges, B; Kelly, PA; Milgrom, E | 1 |
| Altendorf, K; Bramkamp, M | 1 |
| Dummer, PM; Rahman, S; Whitworth, JM | 1 |
| Baseren, M; Gokalp, S; Yazici, AR | 1 |
| Al-Wahb, M; Ankersmidt-Udy, AE; Bohm, E; Cottier, K; Ford, CA; Holloway, H; Smits, B; Snell, RG; Spelman, RJ; Stanfield, AM; Sutherland, GT; Walden, A | 1 |
| Bagorda, F; Lehmann, K; Teuchert-Noodt, G | 1 |
| Koffas, M; Stephanopoulos, G | 1 |
| Kohwi-Shigematsu, T; Mian, IS; Nakayama, Y; Ogawa, T | 1 |
| Damjanović, A; García, AE; García-Moreno, B; Lattman, EE | 1 |
| Anglés-Cano, E; Ho-Tin-Noé, B; Lijnen, HR; Rojas, G; Vranckx, R | 1 |
| Georgi, T; Rittmann, D; Wendisch, VF | 1 |
| Peterson, BZ; Ponoran, TA; Ragsdale, DS; Rasmusson, RL; Wang, X | 1 |
| Hurley, TD; Larson, HN; Weiner, H | 1 |
| Huynh, VT; Kumaresan, PR; Lee, JK; Mathew, PA; Mathew, SO | 1 |
| Black, S; Samols, D; Wilson, A | 1 |
| Date, T; Kato, T; Li, Y; Miyamoto, M; Wakita, T; Yasui, K; Zhao, Z | 1 |
| Bagchi, B; Bhimalapuram, P; Mukherjee, A | 1 |
| Baig, R; Lacey, MG; Loucif, KC; Stanford, IM; Wilson, CL | 1 |
| Eckert, KA; Hamid, S | 1 |
| Marti, DN | 1 |
| Cukier, RI; Ferguson-Miller, S; Mills, DA; Seibold, SA | 1 |
| Hu, M; Nicholas, RA; Seifert, HS; Tobiason, DM; Zhao, S | 1 |
| Dammaschke, T; Danesh, G; Eickmeier, M; Ott, KH; Schäfer, E | 1 |
| Bergmann, D; Bergmann, J; Clode, MJ; Kultje, C; Leitão, J | 1 |
| Du, Z; James, TL; Lee, JK; Li, S; Pan, H; Stroud, RM; Tjhen, R | 1 |
| Bharanidharan, D; Gautham, N | 1 |
| Aoki, M; Fukao, T; Fukutomi, O; Inoue, R; Kaneko, H; Kasahara, K; Kondo, N; Matsui, E; Shinoda, S; Teramoto, T; Yoshikawa, K | 1 |
| Balciuniene, I; Juskiene, I; Sabalaite, R | 1 |
| Fisher, JF; Meroueh, SO; Mobashery, S; Schlegel, HB | 1 |
| Kida, Y; Mihara, K; Morimoto, F; Sakaguchi, M | 1 |
| Burkhard, H; Hotz, P; Klaiber, B; Zesewitz, H | 1 |
| Morrow, LA; Silikas, N; Watts, DC; Wilson, NH | 1 |
| Fujita, D; Matsumoto, Y; Miyoshi, H; Mogi, T; Murai, M; Sakamoto, K; Yoshida, M | 1 |
| Mathé, C; Mattioli, TA; Nivière, V | 1 |
| Galvin, JE; Pandey, N; Schmidt, RE | 1 |
| Arnold, E; Curr, KA; Darden, T; Hamburgh, ME; Monaghan, M; Prasad, VR; Preston, BD; Rao, VR; Sarafianos, S; Tripathi, S | 1 |
| Abdelaziz, KM; Aboulenien, N; El-Kholany, NR; Zaghloul, NM | 1 |
| Kawasaki, M; Zhang, Y | 1 |
| Beau, F; Cuniasse, P; David, A; Devel, L; Dive, V; Makaritis, A; Rogakos, V; Yiotakis, A | 1 |
| Hossain, M; Kimura, Y; Kinoshita, JI; Matsumoto, K; Shimizu, Y; Yamada, Y | 1 |
| Jing, N; Shao, H; Tweardy, DJ; Xu, X | 1 |
| Baggenstoss, BA; Kumari, K; Parker, AL; Weigel, PH | 1 |
| Borde, M; Comas, V; Curti, S; Rivero, C | 1 |
| Imaizumi, A; Kojima, H; Matsui, K | 1 |
| Hui, R; Song, L; Wang, H; Wang, J; Wang, S; Wang, X; Yao, Y; Zheng, W; Zou, Y | 1 |
| Debette, S; Ferrarese, C; Genius, J; Grau, AJ; Grond-Ginsbach, C; Lichy, C; Longoni, M; Schwaninger, M | 1 |
| Ikeda, M; Ohnishi, J | 1 |
| González, H; Lozano-Chourio, MA; Quero, M; Zambrano, O | 1 |
| Dammaschke, T; Danesh, G; Ott, KH; Schäfer, E; Stratmann, U | 1 |
| Dar, DE; Metzger, TG; Uhl, GR; Vandenbergh, DJ | 1 |
| Genadiev, TT; Kirazov, EP; Kirazov, LP; Naydenov, CL | 1 |
| Minvielle, F; Mundy, NI; Nadeau, NJ | 1 |
| Breuning, MH; Kant, SG; Karperien, M; Kruithof, MF; Pereira, AM; Romijn, JA; van der Kamp, HJ; van Duyvenvoorde, HA; Walenkamp, MJ; Wit, JM | 1 |
| Landfear, SM; Liu, W; Ullman, B; Valdés, R | 1 |
| He, Y; Luo, Y; Qian, X; Wu, Y | 1 |
| Baldeck, JD; Marquis, RE; Nguyen, PT; Olsson, J; Sheng, J | 1 |
| Cecchini, G; Hellwig, P; Kotlyar, V; Maklashina, E; Rothery, RA; Sher, Y; Weiner, JH | 1 |
| Briggs, CE; Darras, BT; Duncan, DR; Kang, PB; Kunkel, LM; Lidov, HG; Rabbat, JC | 1 |
| Heyduck, C; Meller, C; Nourallah, AW; Splieth, CH; Steffen, H | 1 |
| Brozovich, FV; Given, AM; Ogut, O | 1 |
| Oria-Hernández, J; Ramírez-Sílva, L; Riveros-Rosas, H | 1 |
| Ahmet, I; Serdar, KS | 1 |
| Grisi, DC; Grisi, MF; Salvador, SL; Sampaio, JE; Theodoro, LH | 1 |
| Bertini, E; Boldrini, R; D'Amico, A; Feng, JJ; Graziano, C; Jacques, A; Laing, N; Limongelli, G; Marston, SB; Nowak, KJ; Pacileo, G; Petrini, S; Porfirio, B; Santorelli, FM; Sewry, CA | 1 |
| Boltshauser, E; Koch, J; Mayr, J; Sperl, W; Strassburg, HM | 1 |
| Gurbuz, T; Kirzioglu, Z; Yilmaz, Y | 1 |
| Castelli, S; Chillemi, G; Desideri, A; Fiorani, P; Losasso, C | 1 |
| Berbis, P; Calvas, P; Chassaing, N; Claudy, A; Cordier-Alex, MP; Hovnanian, A; Kanitakis, J; Sportich, S; Titeux, M | 1 |
| Estabrook, RA; Reich, N | 1 |
| Anderson, JS; Hernández, G; LeMaster, DM | 1 |
| Burrow, MF; Sakoolnamarka, R; Swain, M; Tyas, MJ | 1 |
| Antonio, AG; Cunha, CB; Maia, LC; Moraes, RS; Primo, LG | 1 |
| Casanova, M; Galán, A; Martínez, JP; Murgui, A; Veses, V | 1 |
| Cyr, T; Fournier, SM; Hefford, MA; Kaplan, H; Simons, BL | 1 |
| Kuroki, Y; Matsushima, N; Mitsuzawa, H; Nishitani, C; Sano, H; Shimizu, T | 1 |
| Adhya, S; Choi, EJ; Dimitriadis, EK; Guo, F; Kar, S; Kotova, SL | 1 |
| Mellors, JW; Parikh, UM; Sheen, CW; Sluis-Cremer, N; Torres, PS; Zelina, S | 1 |
| Knöpfel, T; Obata, K; Uusisaari, M | 1 |
| Aittakorpi, A; Isosomppi, J; Sankila, EM; Vastinsalo, H | 1 |
| Imada, T; Mase, M; Okamatsu, M; Tanimura, N; Tsukamoto, K; Yamaguchi, S | 1 |
| Li, G; Liang, A; Ren, L; Wang, Z; Yang, B; Zhao, Y | 1 |
| Cerny, RL; Hage, DS; Wa, C | 1 |
| Eboda, NN; Feigal, RJ; Flamenbaum, MH; Inglehart, MR; Peters, MC | 1 |
| Lenters, M; Mandari, GJ; van Amerongen, WE | 1 |
| Mandari, GJ; Mhaville, RJ; van Amerongen, WE | 1 |
| Mandari, GJ; Roeleveld, AC; van Amerongen, WE | 1 |
| Li, Y; Wang, Y; Yan, H | 1 |
| Andersson, R; Lindman, B; Nehéz, L; Tingstedt, B | 1 |
| Catalucci, D; Ceci, M; Condorelli, G; Gallo, P; Grimaldi, S; Hilfiker-Kleiner, D; Latronico, MV; Missol-Kolka, E; Pitisci, A; Santonastasi, M; Scimia, MC | 1 |
| Chen, D; Frey, PA; Tanem, J | 1 |
| Grisi, DC; Marcantonio, RA; Salvador, SL | 1 |
| Ballmer-Weber, BK; Holzhauser, T; Rösch, P; Vieths, S; Wangorsch, A | 1 |
| Schneider, SP; Walker, TM | 1 |
| Chiu, WC; Huang, SW; Hung, CL; Hwang, JK; Liu, JH; Wang, WC | 1 |
| Aasly, JO; Farrer, MJ; Haugarvoll, K; Ross, OA; Toft, M; White, LR | 1 |
| Colinet, H; Gagneul, D; Kostál, V; Lalouette, L; Renault, D | 1 |
| Dolzan, V; Herman, D; Ingelman-Sundberg, M | 1 |
| Bindoff, LA; Farbu, E; Krossnes, BK; Mørk, S; Tysnes, OB | 1 |
| Gawlak, G; Koide, A; Koide, S; Makabe, K; Tereshko, V; Yan, S | 1 |
| Clementino-Luedemann, TN; Dabanoglu, A; Hickel, R; Ilie, N; Kunzelmann, KH | 1 |
| Edgerton, GB; Fozzard, HA; Hanck, DA; Lipkind, GM; McNulty, MM; Shah, RD | 1 |
| Abdel-Razeq, H; Al-Gaili, F; Al-Hilali, A; Herrmann, FH; Saud, KA; Wulff, K | 1 |
| Daffé, M; Gebhardt, H; Krämer, R; Meniche, X; Morbach, S; Tropis, M | 1 |
| Chikova, A; Dalal, S; DiMaio, D; Lang, T; Sweasy, JB | 1 |
| Corrêa, FN; Muench, A; Rocha, Rde O; Rodrigues Filho, LE; Rodrigues, CR | 1 |
| Hossain, M; Kimura, Y; Masuda, Y; Matsumoto, K; Nakamura, Y; Shimizu, Y; Yamada, Y | 2 |
| Markovic, D; Peric, T | 1 |
| Cherney, MM; Clay, MD; Deyholos, MK; Flegel, MD; James, MN; Marcus, SL; van Belkum, MJ; Vederas, JC; Watanabe, N | 1 |
| Oldfors, A; Swash, M; Tajsharghi, H | 1 |
| Jones, M; Kerrick, WG; Lopaschuk, GD; Moore, JR; Szczesna-Cordary, D; Wagg, C; Wang, Y; Watt, J; Xu, Y | 1 |
| Kalamajski, S; Oldberg, Å | 1 |
| De Grandis, E; De Negri, E; Doria Lamba, L; Follo, R; Giribaldi, G; Pintaudi, M; Veneselli, E | 1 |
| Kennan, AJ; Ryan, SJ | 1 |
| Chatterjee, N; Daugherty, SE; Fallin, MD; Hayes, RB; Huang, WY; Isaacs, WB; Platz, EA; Shugart, YY; Welch, R | 1 |
| Bonci, A; Borgland, SL; Kharazia, VN; Sarti, F | 1 |
| Bennett, TM; Hanson, PI; Knopf, HL; Niikawa, N; Shiels, A; Shim, S; Yamada, K; Yoshiura, K | 1 |
| Cerny, RL; Clarke, WA; Hage, DS; Wa, C | 1 |
| Ahmad, R; Cheng, RP; Girinath, P | 1 |
| Kutsche, K; Shaw, GM; Wimplinger, I | 1 |
| Cheng, KC; Connor, JR; Goodman, SI; Housman, C; Jacobs, RE; LaNoue, K; Lazovic, J; O'Callaghan, JP; Simpson, I; Woontner, M; Zinnanti, WJ | 1 |
| Carver, JA; Ecroyd, H; Meehan, S; Treweek, TM; Walker, MJ; Williams, DM | 1 |
| Fujiyoshi, Y; Hirai, T; Kidera, A; Mitsuoka, K | 1 |
| Aniskina, AI; Chalisova, NI; Filippov, SV; Zakutskii, AN; Zezyulin, PN | 1 |
| Andel, M; Cejková, P; Cerná, M; Kolostová, K; Kucera, P; Novák, J; Nováková, D; Novota, P; Weber, P; Zdárský, E | 1 |
| Bae, E; Bingman, CA; Lee, JE; Phillips, GN; Raines, RT | 1 |
| Butinar, D; Christodoulou, K; Koutsou, P; Starr, A; Zidar, J | 1 |
| Cheng, HC; Gayler, KR; Gunawardana, D | 1 |
| Allis, CD; Duncan, EM; Fischle, W; Li, H; Liang, L; Murakami-Ishibe, S; Patel, DJ; Wang, W | 1 |
| Ahmed, RP; Arteaga, GM; Rajan, S; Solaro, RJ; Warren, CM; Wieczorek, DF | 1 |
| Bai, C; Fukao, T; Kaneko, H; Kasahara, K; Kato, Z; Kimata, K; Kondo, N; Matsui, E; Ohnishi, H | 1 |
| Chiappetta, G; De Gisi, S; De Marco, C; De Rosa, N; Fabiani, F; Franco, R; Malanga, D; Malara, N; Pirozzi, G; Rocco, G; Savino, R; Scrima, M; Tirino, V; Viglietto, G | 1 |
| Cohen, P; Hesson, L; Morton, S; Peggie, M | 1 |
| Baitei, EY; Raef, H; Shi, Y; Zou, M | 1 |
| Bandler, PE; Cole, SP; Deeley, RG; Grant, CE; Westlake, CJ | 1 |
| Corrêa, FN; Rodrigues Filho, LE; Rodrigues, CR | 1 |
| Jeong, EG; Kim, MS; Lee, SH; Yoo, NJ | 1 |
| Anzai, T; Hobo, S; Niwa, H | 1 |
| Hasan, A; Hosein, T | 1 |
| Bastian, BC; Bauer, J; Lutzky, J | 1 |
| Brito-Madurro, AG; Cursino-Santos, JR; Madurro, JM; Martinez-Rossi, NM; Peres, NT; Prade, RA; Rossi, A; Santos, MA | 1 |
| Babu, KL; Neeraja, G; Subramaniam, P | 1 |
| Ishida, T; Kinoshita, K; Shirota, M | 1 |
| Alemán, C; Casanovas, J; Curcó, D; Flores-Ortega, A; Nussinov, R; Zanuy, D | 1 |
| Giza, S | 1 |
| Irie, K; Masuda, Y; Nakanishi, A; Ohashi, R; Shimizu, T; Shirasawa, T; Takegoshi, K | 1 |
| Clerici, F; Contri, P; Di Fede, G; Elia, A; Girotti, F; Mariani, C; Tagliavini, F | 1 |
| Lindner, SN; Rittmann, D; Wendisch, VF | 1 |
| Du, S; Guo, Y; Li, J; Wang, J; Wang, T; Wu, D; Yan, J; Zhang, A; Zhang, X | 1 |
| Chen, Y; Xing, G; Zhang, J; Zhao, Y | 1 |
| Doniach, S; Sim, AY; Sivaramakrishnan, S; Spink, BJ; Spudich, JA | 1 |
| Brusco, A; Cagnoli, C; Di Bella, D; Di Donato, S; Gellera, C; Mariotti, C; Seri, M; Taroni, F | 1 |
| Corrêa, FN; Rocha, RO; Rodrigues, CR; Rodrigues-Filho, LE; Soares, FZ | 1 |
| González, MI; Krizman-Genda, EN; Robinson, MB; Sheldon, AL; Susarla, BT | 1 |
| Darwin, KH; Ferreyra, J; Gygi, SP; Mintseris, J; Pearce, MJ | 1 |
| An, J; Bear, JE; Cyster, JG; Föger, N; Goodnow, CC; Grigorova, IL; Jenne, CN; Lebet, T; Paris, K; Puck, JM; Roadcap, DW; Shiow, LR; Sorensen, RU; Watson, SR; Xu, Y | 1 |
| BODANSKY, O | 1 |
| Osredkar, J; Petrovic, D; Petrovic, MG; Saraga-Babić, M | 1 |
| Chalisova, NI; Zakutskii, AN | 1 |
| Cherney, MM; Clay, MD; James, MN; van Belkum, MJ; Vederas, JC; Watanabe, N | 1 |
| Falke, JJ; Landgraf, KE; Pilling, C | 1 |
| Dong, C; Ernyei, AJ; Flecks, S; Naismith, JH; Patallo, EP; Schneider, A; Seifert, G; van Pée, KH; Zhu, X | 1 |
| Chen, PS; Chen, YJ; Lin, JS; Liu, HM; Lyou, JY; Tzeng, CH | 1 |
| Pan, YP; Shao, LN; Wang, XL; Zhan, FL | 1 |
| Chen, RY; Gao, P; Yang, ZW; Zhang, JM; Zhang, LF; Zhang, YR | 1 |
| Arakaki, RF; Florez, JC; Goldstein, BJ; Hanson, RL; Jablonski, KA; Kahn, SE; Kitabchi, AE; Knowler, WC; Mason, CC; McAteer, JB; Moore, AF | 1 |
| Breitung, K; Eschrich, K; Hannig, M; Kneist, S; Remmerbach, T; Rupf, S; Schellenberger, W | 1 |
| Andjelic, S; Badr, S; Cauli, B; Gallopin, T; Hill, EL; Hu, E; Lambolez, B; Roux, L; Tamás, G | 1 |
| Calvin, K; Ellis, C; Li, H; Mitchell, MH; Xue, S | 1 |
| Aizawa, Y; Chinushi, M; Hanawa, H; Horie, M; Ikrar, T; Ramadan, MM; Watanabe, H | 1 |
| Eden, E; Frencken, JE; Oncag, O; Topaloglu-Ak, A | 1 |
| Holyavka, MG; Kovaleva, TA; Kozhedub, SV; Rezvan, SG | 1 |
| Bi, H; Fukamachi, T; Kobayashi, H; Saito, H; Sun, L | 1 |
| Seeger, MA; van Veen, HW | 1 |
| Adeola, O; Asem, EK; Onyango, EM | 1 |
| Crawford, ED; Fairman, R; Kokona, B; Pellegrino, LD; Root, BC | 1 |
| Bai, J; Jiang, X; Shen, D; Wan, J; Wang, T | 1 |
| Gao, WJ; Wang, HX | 1 |
| Kim, JY; Liao, L; Park, SK; Yates, JR | 1 |
| Gough, JE; Hirst, AR; Hodson, NW; Jayawarna, V; Richardson, SM; Saiani, A; Ulijn, RV | 1 |
| Chang, WC; Horng, JT; Hsu, JB; Hsu, PC; Huang, HD; Lee, TY; Shien, DM; Wang, TY | 1 |
| Hansen, PE; Tomlinson, JH; Ullah, S; Williamson, MP | 1 |
| Du, L; He, Y; Luo, Y; Osman, KT | 1 |
| Meredith, SC; Orgel, JP; Sciarretta, KL; Tycko, R | 1 |
| Altmeyer, M; Fey, M; Hassa, PO; Hottiger, MO; Messner, S | 1 |
| Diver, M; Jain, R; Keppetipola, N; Meineke, B; Shuman, S | 1 |
| Markovic, D; Peric, T; Petrovic, B | 1 |
| Mingote, A; Müller, V; Santos, H; Saum, R | 1 |
| Chu, CC; Lee, HL; Lin, M | 1 |
| Liu, B; Wang, F; Wang, W; Wang, Z; Zhang, Z | 1 |
| Chen, H; Kimelberg, HK; Ma, L; Schools, GP; Xie, M; Xu, G; Zhang, X; Zhou, M | 1 |
| Capellari, S; Di Fede, G; Mancuso, M; Moretti, P; Murri, L; Orsucci, D; Parchi, P; Siciliano, G; Strammiello, R; Suardi, S; Tagliavini, F | 1 |
| Budka, H; Ghetti, B; Haraszti, L; Horvath, S; Kovacs, GG; Majtenyi, K; Molnar, MJ; Murrell, JR; Spina, S | 1 |
| Becchi, M; Francina, A; Joly, P; Préhu, C; Riou, J; Wajcman, H; Zanella-Cleon, I | 1 |
| Furukawa, F; Ishii, N; Kanazawa, N; Kosaka, M; Li, HJ; Nakatani, Y; Ozaki, M | 1 |
| Anderson, B; Bogomolovas, J; Granzier, H; Greaser, M; Hidalgo, C; Hudson, B; Labeit, S; Zhu, Y | 1 |
| Ahmed, SH; Lindsey, ML | 1 |
| Alvarez-Ordóñez, A; Bernardo, A; Fernández, A; López, M | 1 |
| Armel, TZ; Leinwand, LA | 1 |
| Berhanu, WM; Masunov, AE; Mikhailov, IA | 1 |
| Bradley, WG; Escala, W; Papapetropoulos, S; Zhai, RG; Zhou, X | 1 |
| Absalan, G; Akhond, M; Sheikhian, L | 1 |
| Jiang, ZL; Liang, AH; Liang, YY; Liu, QY | 1 |
| Bode, AM; D'Angelo, I; Dong, Z; Kurinov, I; Liu, K; Malakhova, M; Shim, JH; Steinman, V; Zheng, D | 1 |
| Brinkrolf, K; Pühler, A; Schröder, J; Tauch, A | 1 |
| Bax, A; Bodner, CR; Dobson, CM; Maltsev, AS | 1 |
| Bello, Z; Grubmeyer, C; Stitt, B | 1 |
| Chen, X; Gong, ZC; Huang, Q; Liu, ZQ; Ren, HY; Sheng, FF; Wu, J; Xu, XJ; Yin, JY; Yu, M; Zhou, HH | 1 |
| Miwa, M; Nagasaka, K; Nagasaka, T; Nakamura, Y; Ohta, E; Shindo, K; Shiozawa, Z; Togashi, S | 1 |
| Bonfardin, VD; Fossat, P; Oliet, SH; Theodosis, DT | 1 |
| Kaetzel, DM; McCorkle, JR; Novak, M; Yang, M; Zhang, Q | 1 |
| Banerjee, A; Cook, RJ; Kellow, S; Mannocci, F; Watson, TF | 1 |
| García-Moreno, B; Karp, DA; Stahley, MR | 1 |
| Brautaset, T; Degnes, KF; Dillingham, R; Ellingsen, TE; Flickinger, MC; Jakobsen, ØM; Krog, A; Naerdal, I; Netzer, R | 1 |
| Chardwiriyapreecha, S; Iwaki, T; Kakinuma, Y; Mukaiyama, H; Sekito, T; Takegawa, K | 1 |
| Bai, YP; Chen, L; Chen, XP; Guo, YJ; Li, L; Li, YJ; Sun, J; Xia, J; Yang, TL; Zhang, GG | 1 |
| Andi, B; Bobyk, KD; Cook, PF; Ekanayake, DK; West, AH | 1 |
| Ge, L; Jiang, W; Li, B; Miao, H; Song, B | 1 |
| Chen, J; Ghosh, K; Gibb, B; Gupta, K; Sharp, R; Van Duyne, GD | 1 |
| Bolis, V; Corno, M; Rimola, A; Ugliengo, P | 1 |
| Håkansson, K; Kalli, A | 1 |
| Gurry, T; Nerenberg, PS; Stultz, CM | 1 |
| Matoba, S; Nakagawa, M; Noto, Y; Shiga, K; Tokuda, T; Tsuchiya, A; Yazaki, M | 1 |
| Bernhardt, R; Bichet, A; Janocha, S; Zöllner, A | 1 |
| Brajusković, G; Cadez, I; Dimitrijević, R; Dobricić, V; Keckarević, D; Keckarević-Marković, M; Kecmanović, M; Romac, S; Savić-Pavićević, D | 1 |
| Biacabe, AG; Budka, H; Höftberger, R; Kapás, I; Kovacs, GG; László, L; Majtenyi, K; Meyronet, D; Perret-Liaudet, A; Quadrio, I; Sciot, R; Seguin, J; Streichenberger, N; Ströbel, T; Vandenberghe, R | 1 |
| Niermann, K; Schneider, J; Wendisch, VF | 1 |
| Baldwin, RL; Sivaramakrishnan, S; Sommese, RF; Spudich, JA | 1 |
| Hanada, N; Koba, H; Nakao, R; Okuda, K; Senpuku, H; Takeuchi, H; Usui, Y; Watanabe, H | 1 |
| Bizzi, A; Bugiani, O; Capobianco, R; Carella, F; Cupidi, C; Di Fede, G; Giaccone, G; Giovagnoli, A; Magoni, M; Mangieri, M; Marcon, G; Mazzoleni, G; Morbin, M; Padovani, A; Patruno, GM; Puoti, G; Romorini, A; Rossi, G; Salmaggi, A; Tagliavini, F | 1 |
| Arai, H; Hashimoto, C; Komano, JA; Maddali, K; Narumi, T; Nomura, W; Ohashi, N; Ozaki, T; Pommier, Y; Suzuki, S; Tamamura, H; Tanaka, T; Tsutsumi, H; Urano, E; Yamamoto, N | 1 |
| Bizzarro, A; Capellari, S; Guglielmi, V; Iannaccone, E; Masullo, C; Minicuci, G; Parchi, P; Servidei, S; Vita, MG | 1 |
| Dürr, KL; Friedrich, T; Seuffert, I | 1 |
| Drayna, D; Fedyna, A; Kang, C | 1 |
| Abate, N; Adams-Huet, B; Bell, J; Chandalia, M; Grundy, SM; Szuszkiewicz, M; Vazquez, M | 1 |
| Chen, Z; Feng, G; He, L; Liu, Y; Liu, Z; Xu, H; Yang, Y; Yu, L; Zhang, D; Zhang, Z; Zhao, T; Zhou, D | 1 |
| Castañeda, CA; Chimenti, MS; García-Moreno E, B; Majumdar, A | 1 |
| Coutinho, E; De Munck, J; Neves, Ade A; Van Meerbeek, B | 1 |
| Kainosho, M; Kamikawai, T; Starodubtseva, EV; Takeda, M; Terauchi, T; Vinogradov, MG | 1 |
| Ataei, F; Bakhtiyari, S; Gerayesh-Nejad, S; Gulkho, S; Hanachi, P; Larijani, B; Meshkani, R; Mohammadi, M; Mohammadtaghvaei, N; Parvaneh, L; Saberi, H; Zargari, M | 1 |
| Hossain, M; Jayawardena, JA; Kimura, Y; Masuda, Y; Nasu, Y; Yamada, Y | 1 |
| Camoin, L; Kulyyassov, A; Lipinski, M; Moio, P; Ogryzko, V; Ramankulov, E; Vertut, D | 1 |
| Bowie, D; Fay, AM; Maclean, DM; Wong, AY | 1 |
| Li, H; Wang, WM; Wen, Q; Yu, SL | 1 |
| Coutinho, E; De Munck, J; Lambrechts, P; Neves, AA; Van Meerbeek, B | 1 |
| Jobin, MP; Schmitt, P; Senouci-Rezkallah, K | 1 |
| Arana-Chavez, VE; Del Cioppo, CV; Imbronito, AV; Okuda, O | 1 |
| Ishii, H; Lee, E; Matsumoto, T; Ozaki, S; Takimoto, T | 1 |
| Abbasi, AZ; del Mercato, LL; Gorzini, SJ; Herrmann, A; Huibers, WH; Kolbe, A; Parak, WJ; Poolman, B; Rivera Gil, P | 1 |
| Bates, RW; Chang, YT; Cheah, WC; Chuang, KH; Golay, X; Kittigowittana, K; Tuang, CY; Yang, CT | 1 |
| Fukamachi, T; Kobayashi, H; Saito, H; Sun, Y | 1 |
| Cardoso, MV; Coutinho, E; de Munck, J; Neves, Ade A; Van Meerbeek, B | 1 |
| Liwo, A; Makowski, M; Scheraga, HA | 1 |
| Liwo, A; Makowski, M; Scheraga, HA; Sobolewski, E | 1 |
| Cichon, S; Deufel, T; Kiehntopf, M; Koch, K; Mühleisen, TW; Nenadic, I; Nöthen, MM; Reichenbach, JR; Rietschel, M; Roebel, M; Sauer, H; Schachtzabel, C; Schlösser, RG; Schultz, CC; Wagner, G | 1 |
| Chen, YG; Hao, PP; Wang, JL; Wang, XL; Zhang, Y | 1 |
| Kim, DS; Kim, HS; Kim, SY; Lee, CH; Park, YE; Yang, DH | 1 |
| Baccei, ML; Li, J | 1 |
| Batish, SD; Biesecker, LG; Blouin, R; Brandt, C; Coppola, G; Ferguson, CJ; Grant, AE; Hoffman, S; Lenk, GM; Meisler, MH; Nicholson, G; Reddel, SW; Scheuerle, A; Simpson, E; Towne, CF; Yasick, M | 1 |
| Busso, CS; Izumi, T; Wedgeworth, CM | 1 |
| Avrova, SV; Borovikov, YS; Karpicheva, OE; Redwood, CS; Robinson, P | 1 |
| Dubey, KD; Ojha, RP | 1 |
| Appel, SA; Blatt, I; Chapman, J; Cohen, OS; Hoffman, C; Prohovnik, I | 1 |
| Farwick, M; Lersch, P; Maczkiewitz, U; Rawlings, AV; Summers, B | 1 |
| Chen, Z; Lan, Y; Liu, L; Liu, S; Ren, G; Shen, Y; Wan, J; Yang, C; Zhang, Y | 1 |
| Bassan, R; Bussini, A; Castagnetti, F; Gnani, A; Intermesoli, T; Rosti, G; Soverini, S; Spinelli, O | 1 |
| Dieni, CV; Markwardt, SJ; Overstreet-Wadiche, L; Wadiche, JI | 1 |
| Almasi, JN; Bushnell, EA; Gauld, JW | 1 |
| Gao, W; Guo, X; Hao, J; Hu, R; Kunishima, S | 1 |
| Bhowmik, AD; Chaudhuri, K; Mukherjee, S; Mukhopadhyay, K; Ray, JG; Roychoudhury, P | 1 |
| Binyamin, O; Canello, T; Cohen, E; Frid, K; Friedman-Levi, Y; Gabizon, R; Mizrahi, M | 1 |
| Geor, RJ; Hanigan, MD; Harris, PA; Urschel, KL | 1 |
| Moosavi, H; Shabzendedar, M; Sharifi, M; Talbi, M | 1 |
| Botond, G; Budka, H; Keller, E; Kovacs, GG; László, L; Molnár, K | 1 |
| Nguyen, TM; Sparks-Thissen, RL | 1 |
| Rezaei, Z; Saadat, I; Saadat, M | 1 |
| Addlagatta, A; Ganji, RJ; Gumpena, R; Jain, N; Kishor, C | 1 |
| Ahmed, BM; Bohari, MR; Chunawalla, YK | 1 |
| Absalan, G; Ghaemi, M | 1 |
| Cook, PF; Kumar, VP; West, AH | 1 |
| McMinn, P; Phuektes, P; Zaini, Z | 1 |
| Gnanasambandan, K; Magis, AT; Sayeski, PP | 1 |
| Manolopoulos, VG; Petridis, I; Ragia, G; Tavridou, A | 1 |
| Qiu, LH; Shao, LN; Zhan, FL; Zhong, M | 1 |
| Balzer, S; Brautaset, T; Ellingsen, TE; Heggeset, TM; Krog, A; Wentzel, A | 1 |
| Cebe, MA; Ozturk, B; Sirin Karaarslan, E; Yegin, Z; Yildiz, E | 1 |
| Calvez, V; Flandre, P; Fofana, DB; Fourati, S; Katlama, C; Lambert, S; Malet, I; Marcelin, AG; Sayon, S; Simon, A; Soulie, C; Wirden, M | 1 |
| Liu, H; Pan, D; Xue, W; Yao, X; Zhang, W | 1 |
| Aikawa, T; Amano, K; Fujimaki, T; Ishiguchi, M; Kimata, M; Kishi, N; Kogo, M; Murakami, A | 1 |
| Chang, WC; Lee, CM; Shyu, BC | 1 |
| Gugnani, N; Gupta, M; Kochhar, GK; Pandit, IK; Srivastava, N | 1 |
| Ahmed, M; Davis, GR; Wong, FS | 1 |
| Ahmad, R; Argiros, A; Cheng, RP; Fairman, R; Girinath, P; Hart, P; Kilpatrick, C; Kokona, B; Li, JH; Wang, WR; Yang, PA | 1 |
| Chung, SH; Hilder, TA | 1 |
| Abe, M; Nomura, K; Sakai, H; Sakai, K; Sakamoto, K; Shrestha, RG; Tamura, Y; Yamamoto, M; Yamawaki, Y | 1 |
| Kameda, T; Sutherland, TD; Walker, AA; Weisman, S | 1 |
| Amachawadi, RG; Elwakeel, EA; Nagaraja, TG; Nasser, ME; Nour, AM; Titgemeyer, EC | 1 |
| Gopinath, V; Lindner, SN; Meiswinkel, TM; Nampoothiri, KM; Wendisch, VF | 1 |
| Barcs, G; Finta, L; Holló, A; Kamondi, A; Osztie, E; Papp, E; Sólyom, A; Szucs, A; Várallyay, P; Varga, D | 1 |
| Balen, AH; Campbell, BK; Hemmings, KE; Hogg, JE; Leese, HJ; Maruthini, D; Picton, HM; Vyjayanthi, S | 1 |
| Albers, SV; Fujimura, T; Horie, A; Kosono, S; Kuramitsu, S; Kuzuyama, T; Lassak, K; Masui, R; Mineki, R; Nishida, H; Nishiyama, C; Nishiyama, M; Ouchi, T; Taka, H; Takahashi, K; Tomita, T; Yoshida, A | 1 |
| Hisamitsu, H; Hossain, M; Kimura, Y; Manabe, A; Masuda, Y; Yamada, Y | 1 |
| Arora, N; Bhalla, M; Bijle, MN; Mumkekar, SS; Murali, KV; Patil, S | 1 |
| Deshpande, MV; Joshi, CV; Kapadnis, BP; Pathan, EK; Punekar, NS; Tupe, SG | 1 |
| Pandian, SK; Selvaraj, C; Shafreen, RM; Singh, SK | 1 |
| McKane, M; Rubenstein, PA; Wen, KK | 1 |
| Fujii, N; Kaku, M; Kawaji, K; Kodama, EN; Matsuoka, M; Miyamoto, F; Oishi, S; Sakagami, Y; Sarafianos, SG; Shimane, K; Shimura, K; Watanabe, K | 1 |
| Babich, JW; Eckelman, WC; Hillier, SM; Joyal, JL; Lu, G; Maresca, KP; Marquis, JC; Merkin, RD; Zimmerman, CN | 1 |
| Baloh, RH; Bouitbir, J; Dupuis, L; Eschbach, J; Fergani, A; Geny, B; Harms, MB; Larmet, Y; Loeffler, JP; Ludolph, AC; Marion, V; Messadeq, N; René, F; Schlagowski, AI; Shy, ME; Sinniger, J; Weydt, P; Zoll, J | 1 |
| Ba, Y; Huang, X; Karush, JM; Lian, J; Liu, N; Lu, X; Mao, H; Wang, Y; Yang, X; Zhou, J | 1 |
| Banks, J; Barclay, WS; Howard, WA; Long, JS; Lycett, S; Moncorgé, O; Núñez, A | 1 |
| Nagarathna, C; Shakuntala, BS; Viral, PM | 1 |
| Boehr, DD; Yezdimer, EM; Zaccardi, MJ | 1 |
| Burrow, MF; Hamama, HH; King, NM; Yiu, CK | 1 |
| Beed, P; Böhm, C; Brecht, M; Burgalossi, A; Gundlfinger, A; Schmitz, D; Schneiderbauer, S; Song, J; Vida, I | 1 |
| Peddada, N; Rathore, YS; Raychaudhuri, S; Singh, NS; Singh, R | 1 |
| Ford, TW; Mauad, H; Michael Spyer, K; Sampaio, KN | 1 |
| Liu, R; Wang, CM; Wang, L; Yang, WH | 1 |
| Blanchard, JS; Hadi, T; Hazra, S; Tanner, ME | 1 |
| Chen, X; Huang, B; Liu, H; Liu, X; Lou, M; Shao, J; Xu, Z; Yang, CG; Zhang, L; Zhu, L; Zhu, W | 1 |
| Cebe, MA; Sirinkaraarslan, E; Tosun, G; Yegin, Z; Yildiz, E | 1 |
| Aggarwal, V; Singla, M; Yadav, H; Yadav, S | 1 |
| Harvey, JN; Marsh, EN; Mulholland, AJ; Román-Meléndez, GD; von Glehn, P | 1 |
| Bai, T; Bo, H; Chen, H; Chen, T; Dong, J; Dong, L; Fan, G; Fan, J; Feng, Z; Gao, GF; Gao, R; Gong, T; Hu, M; Jin, Q; Lan, Y; Li, D; Li, H; Li, J; Li, Q; Li, X; Liu, M; Ni, X; Shi, Y; Shu, Y; Wan, J; Wang, D; Wang, S; Wang, Y; Wu, G; Wu, J; Xiong, Y; Yang, F; Yang, L; Yang, W; Yuan, H; Zhang, J; Zhang, Y; Zhao, X; Zhou, J; Zhou, X; Zou, S | 1 |
| Capone, I; Cervellati, C; Dallocchio, F; Hanau, S; Montin, K; Proietti d'Empaire, L | 1 |
| Alam, S; Atkinson, C; Janciauskiene, S; Jonigk, D; Li, Z; Mahadeva, R | 1 |
| Blum, MM; Breyer, F; John, H; Schmidt, C; Thiermann, H; Worek, F | 1 |
| Li, R; Ye, L; Zhao, Y | 1 |
| Adame, A; Campioni, S; Gage, FH; Gerez, J; Jensen, PH; Mante, M; Masliah, E; Nuber, S; Overk, CR; Patrick, C; Picotti, P; Riek, R; Rockenstein, E; Trejo-Morales, M; Ubhi, K; Winkler, J; Winner, B | 1 |
| Andeen, NK; de Boer, IH; Lam, DY; Nicosia, RF | 1 |
| Basu, G; Chongdar, N; Dasgupta, S; Datta, AB | 1 |
| Hazen, RM; Lee, N; Sverjensky, DA | 1 |
| Chen, S; Li, W; Liu, L; Wang, G; Wang, L; Wang, Z; Yang, Q | 1 |
| Elyada, A; Füredi-Milhofer, H; Garti, N | 1 |
| Czeizel, E; Kádasi, ĽL; Vogt, G | 1 |
| Burrow, M; Hamama, H; Yiu, C | 1 |
| Ammari, MM; Coutinho Filho, WP; Hirata Júnior, R; Moliterno, LF; Séllos, MC; Soviero, VM | 1 |
| Chen, W; He, Q; Lin, X; Ren, Z; Wang, F; Xing, X; Xu, J | 1 |
| Burrow, MF; Hamama, HH; Yiu, CK | 3 |
| Kirk, KL; Roessler, BC; Wang, W | 1 |
| Chang, YC; Lee, IC; Liu, YC; Shen, CN; Tsai, HA | 1 |
| Batchelor, M; Gowdy, J; Paci, E | 1 |
| Chen, Y; Cui, L; Cui, Z; Li, M; Shang, R; Sun, Y; Xu, F | 1 |
| Sharma, A; Soni, HK; Sood, PB | 1 |
| Brautaset, T; Heggeset, TM; Müller, JE; Vorholt, JA; Wendisch, VF | 1 |
| Boucher, E; Casaz, P; Ozturk, S; Pierce, BG; Rivera, R; Sedic, M; Thomas, WD; Wang, Y; Wollacott, R | 1 |
| Fujimura, S; Kadowaki, M; Kobayashi, H; Kubota, M; Shibata, M; Watanabe, G | 1 |
| Appel, S; Chapman, J; Cohen, OS; Hoffmann, C; Kahana, E; Korczyn, AD; Lee, H; Nitsan, Z; Rosenmann, H | 1 |
| Andrews, C; Balasubramanian, R; Chan, WM; Chew, S; Engle, EC; Kang, PB; MacKinnon, SE | 1 |
| Bartuschat, AL; Gmeiner, P; Heinrich, MR; Hübner, H; Schellhorn, T | 1 |
| Ball, J; Bui, QV; Gadda, G; Gannavaram, S | 1 |
| Chang, HC; Cheng, RP; Chiu, WC; Fang, CJ; Huang, SJ; Huang, SL; Kuo, HT; Li, JH; Liu, SL; Wang, WR; Yang, PA | 1 |
| Baker, EG; Bartlett, GJ; Crump, MP; Faul, CF; Linden, N; Sessions, RB; Woolfson, DN | 1 |
| Goodwin, DC; Huang, J; Panizzi, JR; Panizzi, P; Smith, F | 1 |
| Almhöjd, U; Cagetti, MG; Campus, G; Cocco, F; Lai, G; Lara Capi, C; Lingström, P | 1 |
| Schreiber, M; Schwalbe, B | 1 |
| Burrow, MF; Hamama, H; Yiu, C | 1 |
| Delfini, M; Gorietti, D; Mannina, L; Miccheli, A; Palleschi, C; Puccetti, C; Saliola, M; Sobolev, AP; Uccelletti, D; Zanni, E | 1 |
| Gnanasambandam, R; Nishizawa, K; Nishizawa, M; Sachs, F; Suchyna, TM; Sukharev, SI | 1 |
| Battú, CE; Broetto, N; Dutra, MF; Galland, F; Gonçalves, CA; Hansen, F; Lirio, F; Nardin, P | 1 |
| Baneyx, F; Coyle, BL; Jiang, S; Keefe, AJ; Liu, EJ; Nannenga, BL; Sinclair, A | 1 |
| Brooks, BR; Damjanović, A; Lee, J; Miller, BT | 1 |
| Darris, C; Ivy, MT; Nahashon, SN; Nelson, K; Payne, A; Stewart, A; Wang, X | 1 |
| Kawamura, Y; Kawasaki, H; Kosono, S; Kubo, S; Mizuno, Y; Nagano-Shoji, M; Nishiyama, M; Yoshida, A; Yoshida, M | 1 |
| Cleto, S; Jensen, JV; Lu, TK; Wendisch, VF | 1 |
| Aguiar-Pulido, V; Huang, W; Kazmierczak, K; Narasimhan, G; Szczesna-Cordary, D; Zhou, Z | 1 |
| Bhaskar, SA; Bolar, DR; Hegde, S; Kakti, A | 1 |
| Biondi, B; Bondesan, A; Cabri, W; Formaggio, F; Guryanov, I; Orlandin, A; Ricci, A; Toniolo, C; Visentini, D; Zanon, J | 1 |
| Meuzelaar, H; Vreede, J; Woutersen, S | 1 |
| Harkness, TC; Hudson, AO; Savka, MA | 1 |
| Arita, M; Cajka, T; Fiehn, O; Kind, T; Nakabayashi, R; Saito, K; Tanaka, W; Tsugawa, H; Yukihira, D | 1 |
| Kagawa, W; Kurumizaka, H; Onodera, K; Saito, K; Saotome, M | 1 |
| Alaayedi, M; Iyire, A; Mohammed, AR | 1 |
| Brain, C; Georgiev, G; Kim, PY; Klemmer, A; Lionikiene, AS; Mitchell, JL; Mutch, NJ | 1 |
| Botuyan, MV; Bruns, CJ; Cui, G; Klein, BJ; Kutateladze, TG; Lin, K; Lu, Y; Mer, G; Shi, X; Wang, X; Yuan, C; Zhao, Y | 1 |
| Dan, N; Dan, W; Liu, X | 1 |
| Amorim Franco, TM; Blanchard, JS; Hegde, S | 1 |
| Kamishina, H; Kato, S; Kobatake, Y; Kohyama, M; Maeda, S; Sakai, H; Sasaki, J; Tsukui, T; Urushitani, M; Yamato, O | 1 |
| Cui, Q; Zheng, Y | 1 |
| Belsham, GJ; Fahnøe, U; Gullberg, M; Kristensen, T; Normann, P; Polacek, C; Rasmussen, TB | 1 |
| Abusalim, G; Arora, R; Bhardwaj, B; Gulzar, S; Khalil, HS; Shah, AH; Wyne, AH | 1 |
| Bonito, CA; Guedes, RC; Leandro, J; Leandro, P; Louro, F; Nunes, J; Ventura, FV | 1 |
| Bruce, IA; Cartmell, SH; Derby, B; Markey, A; Miller, AF; Saiani, A; Woolford, TJ; Workman, VL | 1 |
| Elsawy, MA; Gao, J; Miller, AF; Saiani, A; Smith, AM; Tang, C | 1 |
| Éltes, T; Holderith, N; Kirizs, T; Nusser, Z | 1 |
| Buttrick, GJ; Del Mar Mora-Santos, M; Hardwick, KG; Lancaster, TC; Meadows, JC; Messin, LJ; Millar, JBA; Sochaj, AM | 1 |
| Hamamoto, Y; Kikuchi, M; Kosono, S; Mizuno, Y; Nagano-Shoji, M; Nishiyama, M; Shirouzu, M; Umehara, T; Yamada, A; Yoshida, M | 1 |
| Cameron, CE; Ciota, AT; Gohara, DW; Griesemer, SB; Kramer, LD; Pata, JD; Van Slyke, GA | 1 |
| Baker, EG; Bartlett, GJ; Batchelor, M; Dougan, L; Knight, PJ; Kurzawa, M; Paci, E; Peckham, M; Wolny, M; Woolfson, DN | 1 |
| Begas, P; Deponte, M; Liedgens, L; Meyer, AJ; Moseler, A | 1 |
| Björk, GR; Jäger, G; Nilsson, K | 1 |
| Geisbrecht, BV; Katz, BB; Ramyar, KX; Walker, JK; Woehl, JL | 1 |
| Lee, JH; Wendisch, VF | 1 |
| Ku, HF; Kuo, YC; Rajesh, R | 1 |
| Adler-Gunzelmann, G; Behrens, VA; Henn, A; Latham, SL; Münnich, S; Taft, MH; Thiel, C | 1 |
| Kawasaki, H; Komine-Abe, A; Kosono, S; Kubo, S; Nagano-Shoji, M; Nishiyama, M; Yoshida, M | 1 |
| Liu, N; Pidaparti, R; Wang, X | 1 |
| Loskarn, S; Masliah, E; Regensburger, M; Rockenstein, E; Schreglmann, SR; Stoll, S; Winner, B; Xiang, W | 1 |
| Matsumoto, H; Nakamura, Y; Nonoyama, S; Uematsu, K; Zaha, K | 1 |
| Bardóczi, Z; Dhillo, WS; Fekete, C; Göcz, B; Hrabovszky, E; Kádár, A; Kalló, I; Maglóczky, Z; Matolcsy, A; Rácz, G; Skrapits, K; Szűcs, I; Takács, S; Váczi, V; Watanabe, M | 1 |
| Holmberg, AR; Lennartsson, L; Marquez, M; Meurling, L; Nilsson, S | 1 |
| Carvalho, PC; Correia, CRD; de Jesus, HCR; Drekener, RL; Ferrari, AJR; Fioramonte, M; Gozzo, FC; Lima, DB; Neves-Ferreira, AGDC; Oliveira, LG | 1 |
| Li, J; Pan, Y; Su, C; Wang, Y; Wei, J; Zhang, X | 1 |
| Gao, SJ; Wu, ZH; Xu, JZ; Zhang, W | 1 |
| Lockridge, O; Schopfer, LM | 2 |
| Gao, J; Guo, Y; Ji, L; Li, J; Li, L; Liu, D; Liu, P; Pan, B; Pennathur, S; Su, J; Wang, Y; Willard, B; Xiang, S; Xu, L; Zhang, D; Zhao, M; Zheng, L | 1 |
| Greenberg, MM; Yang, K | 1 |
| Jiang, S; Liu, EJ | 1 |
| Hwang, S; Nicholson, EM | 1 |
| Chun, S; Chung, HJ; Jeong, BH; Kim, HK; Kwon, YD; La, MT; Lee, SH; Lee, SJ; Oh, JM | 1 |
| Khan, RU; Li, L; Qu, F; Wang, X | 1 |
| Brandt, C; Klein, J; Löscher, W; Meller, S; Theilmann, W | 1 |
| Dai, B; Deng, Y; Huang, S | 1 |
| Leon, L; Tabandeh, S | 1 |
| Baker, D; Brady, AF; Burrows, N; Cervi, E; Cilliers, D; Frank, M; Germain, DP; Ghali, N; Hulmes, DJS; Jacquemont, ML; Kannu, P; Lefroy, H; Legrand, A; Pope, FM; Robertson, L; van Dijk, FS; Vandersteen, A; von Klemperer, K; Warburton, R; Whiteford, M | 1 |
| Cheng, SH; Fieles, W; Geske, R; Hong, H; Hu, E; Isidro-Llobet, A; Jucker, BM; Klein, JL; Lee, D; Lenhard, SC; McAlexander, A; Nadin, A; Rambo, M; Skedzielewski, T; Trinh, H; Virtue, A | 1 |
| Steinbüchel, A; Wiefel, L; Wohlers, K | 1 |
| Chitama, BA; Kagaya, W; Kaneko, O; Miyazaki, S; Yahata, K; Zhu, X | 1 |
| Achille, A; Bartels, T; Fonseca-Ornelas, L; Jiang, H; Langen, R; Patel, DS; Pitino, JC; Powers, AE; Rovere, M; Varkey, J | 1 |
| Bredeston, LM; Ebert, B; Favarolo, MB; Gonzalez Flecha, FL; Rautengarten, C; Toscanini, MA | 1 |
| Li, Q; Wang, S; Wu, J; Yang, P; Ying, H; Zhou, J; Zhu, S; Zhuang, W | 1 |
| Gonzalez-Pech, NI; Grassian, VH; Ustunol, IB | 1 |
| Feng, Q; Li, W; Liu, L; Ma, L; Shen, X; Sun, X; Wang, J; Yan, Y; Yuan, Q; Zheng, G | 1 |
| Halder, R; Jana, B | 1 |
| Mi, YY; Song, NH; Wang, ZJ; Yuan, W; Zhang, LF; Zhang, W; Zhu, LJ; Zuo, L | 1 |
| Habib, ZF; Huang, CLH; Hwang, SS; Irons, JR; Jackson, AP; Salvage, SC; Silva, JR; Zhu, W | 1 |
| Mandal, I; Manna, S; Venkatramani, R | 1 |
| Biswas, A; Chakraborty, A; Nandi, SK; Panda, AK | 1 |
| Chen, L; Liu, Q; Pang, X; Wu, J; Yang, H; Zhao, X | 1 |
| Khavinson, VK; Kormilets, DY; Kuznik, BI; Linkova, NS; Mar'yanovich, AT; Terekhov, AY | 1 |
| Castro-Puyana, M; Marina, ML; Salido-Fortuna, S | 1 |
| Ben Halima, M; Boudiche, S; Larbi, N; Mghaieth Zghal, F; Mourali, MS; Rekik, B | 1 |
| Jia, J; Ma, YZ; Sun, DG; Wang, DS; Wang, LX; Wu, D; Xin, BC | 1 |
| Shao, Q | 1 |
| Dighe, K; Maru, VP; Padawe, D; Takate, V; Tripathi, VP; Vishwanath Dalvi, S | 1 |
| He, Y; Jain, P; Jiang, S; Li, B; McMullen, P; Niu, L; Tang, C; Yuan, Z | 1 |
| Du, J; Lü, W; Osei-Owusu, J; Qiu, Z; Ruan, Z | 1 |
| Aharon, E; Despotović, D; Gruic-Sovulj, I; Kahana, A; Longo, LM; Scherf, T; Tawfik, DS | 1 |
| Ayala-Rodríguez, JÁ; de la Cruz, HR; Guevara-García, ÁA; López-Bucio, J; López-Bucio, JS; Pelagio-Flores, R; Ravelo-Ortega, G; Ruiz-Herrera, LF | 1 |
| Friedrich, MG; Schey, KL; Truscott, RJW; Wang, Z | 1 |
| Cerqueira, NMFSA; Silva Teixeira, CS; Sousa, SF | 1 |
| Bollati, M; de Rosa, M; Drnovšek-Olup, B; Fakin, A; Gornik, A; Hawlina, M; Hočevar, A; Jaklič, H; Maver, A; Peterlin, B; Pfeifer, V; Pižem, J; Potrč, M; Teran, N; Vogelnik, K; Volk, M | 1 |
| Bararpour, N; Darrous, L; Froguel, P; Gasser, M; Gilardi, F; Kutalik, Z; Marques-Vidal, P; Porcu, E; Thomas, A; Waeber, G; Yengo, L | 1 |
| Chen, S; Guo, Y; Lin, W; Xu, L | 1 |
| Lu, L; Ma, D; Xi, Z; Yang, C; Yang, X | 1 |
| Kim, IH; Kim, YH; Lee, SS; Upadhaya, SD; Wu, Z | 1 |
| Alfiler, L; Anastassiou, C; Arkhipov, A; Baker, K; Bakken, TE; Barkan, E; Barzo, P; Beller, A; Berg, J; Bernard, A; Berry, K; Bertagnolli, D; Bickley, K; Bomben, J; Braun, T; Brouner, K; Buchin, A; Budzillo, A; Casper, T; Chartrand, T; Chong, P; Cobbs, C; Crichton, K; D'Orazi, F; Dalley, R; de Frates, R; de Kock, CPJ; de Witt Hamer, PC; Dee, N; Desta, T; Ding, SL; Dotson, N; Egdorf, T; Ellenbogen, RG; Enstrom, R; Esposito, L; Farrell, C; Feng, D; Ferreira, M; Fong, O; Furdan, S; Galakhova, AA; Gamlin, C; Gary, A; Glandon, A; Goldy, J; Gorham, M; Goriounova, NA; Gouwens, NW; Gratiy, S; Graybuck, L; Gu, H; Gwinn, RP; Hadley, K; Hansen, N; Hawrylycz, MJ; Heistek, TS; Henry, AM; Heyer, DB; Hill, C; Hill, D; Hodge, RD; Hof, PR; Hupp, M; Idema, S; Jarsky, T; Jones, AR; Kalmbach, B; Kebede, S; Keene, CD; Keene, L; Kim, L; Kim, MH; Ko, AL; Koch, C; Kroll, M; Latimer, C; Lee, BR; Lee, C; Lee, SD; Lein, ES; Levi, BP; Link, KE; Mallory, M; Mann, R; Mansvelder, HD; Marshall, D; Maxwell, M; McGraw, M; McMillen, D; Melief, E; Mertens, EJ; Mezei, L; Mihut, N; Miller, JA; Mok, S; Molnar, G; Mukora, A; Murphy, GJ; Ng, L; Ngo, K; Nicovich, PR; Nyhus, J; Ojemann, JG; Olah, G; Oldre, A; Omstead, V; Ozsvar, A; Park, D; Patel, AP; Peng, H; Pham, T; Phillips, JW; Pom, CA; Potekhina, L; Rajanbabu, R; Ransford, S; Reid, D; Rimorin, C; Ruiz, A; Sandman, D; Segev, I; Silbergeld, DL; Smith, K; Sorensen, SA; Sulc, J; Sunkin, SM; Szafer, A; Szemenyei, V; Tamas, G; Tasic, B; Thomsen, ER; Tieu, M; Ting, JT; Torkelson, A; Trinh, J; Tung, H; Wakeman, W; Waleboer, F; Ward, K; Wilbers, R; Williams, G; Yao, Z; Yoon, JG; Yuste, R; Zeng, H | 1 |
| Behnke, M; Bonduelle, C; Klemm, P; Lecommandoux, S; Schubert, S; Solomun, JI; Traeger, A | 1 |
| Gu, F; Liu, YC; Wang, M; Wei, N; Yang, FY; Zhang, LF; Zhang, ZH | 1 |
| Dickeson, SK; Feener, EP; Gailani, D; Kumar, S; Law, RHP; Mohammed, BM; Phillips, DR; Quek, AJ; Sun, MF; Whisstock, JC | 1 |
| Irla, M; Wendisch, VF | 1 |
| Kaplan, AP | 1 |
| Bratu, DC; Dragoș, B; Luca, MM; Nikolajevic-Stoican, N; Pop, SI; Popa, G | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Ba, Z; Chang, L; Gou, S; Li, B; Liu, H; Ni, J; Ouyang, X; Yang, Y; Zhang, F; Zhang, J; Zhang, T; Zhang, Y | 1 |
| Le, TV; Lee, SW | 1 |
| Chen, J; Liu, HS; Liu, SB; Sa, RN; Tan, HZ; Wang, YM; Xie, JJ; Yu, Y; Zhao, F; Zou, Y | 1 |
| Guan, W; Orellana, KG; Spafford, JD; Stephens, RF; Zhorov, BS | 1 |
| Aguilar-Díaz, H; Cossio-Bayugar, R; Mera-Y-Sierra, R; Miranda-Miranda, E; Narváez-Padilla, V; Neira, G; Reynaud, E; Scarcella, S | 1 |
| Abousaida, B; Carter, R; Derry, P; Gonzalez, VV; Kim, JBK; Krishnan, S; Liopo, AV; Mackeyev, Y; Rauta, PR; Sanders, K; Shohayeb, MA; Singh, P; Tezcan, O; Vijay, GV; Zahra, Y; Zubarev, ER | 1 |
| Lockridge, O; Muñoz-Torrero, D; Schopfer, LM | 1 |
| Fossat, MJ; Pappu, RV; Posey, AE | 1 |
| Akkaoui, K; Chen, Y; Digby, ZA; Schlenoff, JB | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Cheng, RP; Huang, SJ; Huang, SL; Li, NZ; Wu, JY; Yu, CH | 1 |
| Hellmann, A; Korczynska, J; Mika, A; Taciak, A; Turyn, J; Zwara, A | 1 |
| Kumar, A; Pospíšil, P; Prasad, A; Sedlářová, M | 1 |
| Bui, TH; Cole, CC; Hartgerink, JD; Misiura, M; Williams, J; Yu, LT | 1 |
26 review(s) available for glutamic acid and lysine
| Article | Year |
|---|---|
Amino acid composition of dentine in permanent human teeth.
Topics: Amino Acids; Asparagine; Aspartic Acid; Dentin; Glutamates; Glutamic Acid; Humans; Hydroxylysine; Lysine | 1992 |
Transglutaminases: multifunctional cross-linking enzymes that stabilize tissues.
Topics: Amino Acid Sequence; Factor XIII; Glutamates; Glutamic Acid; Humans; Keratinocytes; Lysine; Molecular Sequence Data; Protein Conformation; Protein Processing, Post-Translational; Sequence Homology, Nucleic Acid; Tissue Distribution; Transglutaminases | 1991 |
Rheogenic transport of basic and acidic amino acids across the brush border of Necturus small intestine.
Topics: Amino Acids; Animals; Biological Transport; Chlorides; Electrophysiology; Glutamates; Glutamic Acid; Intestine, Small; Lysine; Microvilli; Necturus; Sodium | 1988 |
Recent advances in the physiology and genetics of amino acid-producing bacteria.
Topics: Amino Acids; Base Sequence; Cloning, Molecular; Corynebacterium; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Engineering; Glutamic Acid; Isoleucine; Lysine; Molecular Sequence Data; Threonine | 1995 |
[Endo-epsilon-(gamma-Glu)Lys-isopeptidolysis as a sign of highly-specific proteolysis].
Topics: Amino Acid Sequence; Animals; Catalysis; Endopeptidases; Fibrinolytic Agents; Glutamates; Glutamic Acid; Humans; Hydrolysis; Lysine; Molecular Sequence Data; Substrate Specificity | 1994 |
Transport mutants and transport genes of Corynebacterium glutamicum.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Base Sequence; Corynebacterium; Genes, Bacterial; Genetic Vectors; Glucose; Glutamic Acid; Lysine; Models, Biological; Molecular Sequence Data; Multigene Family; Mutation; Plasmids; Restriction Mapping | 1996 |
Chemochemical caries removal: a review of the techniques and latest developments.
Topics: Biodegradation, Environmental; Collagen; Dental Caries; Dental Cavity Preparation; Dentin; Gels; Glutamic Acid; Humans; Leucine; Lysine; Surface Properties | 2000 |
Lysine catabolism: a stress and development super-regulated metabolic pathway.
Topics: Animals; Arabidopsis; Base Sequence; Central Nervous System; Gene Expression Regulation, Plant; Glutamic Acid; Humans; Lysine; Phosphoprotein Phosphatases; Plant Proteins; Protein Kinases; Saccharopine Dehydrogenases | 2001 |
[Chemo-mechanical caries removal: a review of the techniques and latest developments].
Topics: Aminobutyrates; Dental Caries; Dental Cavity Preparation; Dentin Solubility; Gels; Glutamic Acid; Humans; Leucine; Lysine | 2001 |
Chemomechanical caries removal: a comprehensive review of the literature.
Topics: Aminobutyrates; Animals; Chloramines; Collagen; Dental Caries; Dental Cavity Preparation; Dental Materials; Dental Pulp; Dental Restoration, Permanent; Dentin; Glutamic Acid; Glycine; Humans; Hydrogen Bonding; Leucine; Lysine; Patient Satisfaction; Time Factors; Urea | 2001 |
[Carisolv, a change in the perception of caries treatment--a chemo-mechanical removal of caries].
Topics: Child; Coloring Agents; Dental Caries; Dental Cavity Preparation; Dental Enamel; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Tooth Preparation | 2003 |
Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region.
Topics: ATP-Binding Cassette Transporters; Chromosome Mapping; Diabetes Mellitus, Type 2; Genotype; Glutamic Acid; Haplotypes; Humans; Islets of Langerhans; Lysine; Models, Genetic; Phenotype; Polymorphism, Single Nucleotide; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors | 2004 |
Structures and mechanisms of Nudix hydrolases.
Topics: Amino Acid Motifs; Amino Acid Sequence; Arginine; Catalysis; Cations, Divalent; Dinucleoside Phosphates; Electron Spin Resonance Spectroscopy; Glutamic Acid; Glycine; Hydrogen Bonding; Hydrolysis; Kinetics; Ligands; Lysine; Models, Molecular; Models, Structural; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nudix Hydrolases; Protein Structure, Secondary; Pyrophosphatases; Substrate Specificity; Water | 2005 |
Strain improvement by metabolic engineering: lysine production as a case study for systems biology.
Topics: Corynebacterium glutamicum; Gene Expression Regulation, Bacterial; Genome, Bacterial; Glutamic Acid; Isotope Labeling; Lysine; Systems Biology | 2005 |
Molecular basis of multidrug transport by ABC transporters.
Topics: Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Binding Sites; Crystallography, X-Ray; Glutamic Acid; Histidine; Humans; Lysine; Models, Biological; Molecular Sequence Data; Pharmaceutical Preparations; Protein Conformation; Protein Structure, Tertiary; Sequence Alignment | 2009 |
The transcriptional regulatory repertoire of Corynebacterium glutamicum: reconstruction of the network controlling pathways involved in lysine and glutamate production.
Topics: Corynebacterium glutamicum; Gene Expression Regulation; Glutamic Acid; Lysine; Transcription, Genetic | 2010 |
Meta-analysis of aldehyde dehydrogenase 2 gene polymorphism and Alzheimer's disease in East Asians.
Topics: Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Alzheimer Disease; Apolipoprotein E4; Asia, Eastern; Confidence Intervals; Databases, Bibliographic; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Lysine; Male; Odds Ratio; Polymorphism, Single Nucleotide | 2011 |
How to make choice of the carious removal methods, Carisolv or traditional drilling? A meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Decision Making; Dental Caries; Dental Cavity Preparation; Dentin; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome; Young Adult | 2014 |
Current update of chemomechanical caries removal methods.
Topics: Aminobutyrates; Chloramines; Dental Caries; Dental Cavity Preparation; Disinfectants; Equipment Design; Glutamic Acid; Glycine; Hardness; Humans; Leucine; Lysine; Papain; Sodium Hypochlorite | 2014 |
The Glu504Lys polymorphism of aldehyde dehydrogenase 2 contributes to development of coronary artery disease.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Alleles; Asian People; Cardiovascular Diseases; Coronary Artery Disease; Genetic Predisposition to Disease; Glutamic Acid; Humans; Inflammation; Lysine; Nitric Oxide Synthase Type III; Oxidative Stress; Polymorphism, Genetic; Risk Factors | 2014 |
Methylotrophy in the thermophilic Bacillus methanolicus, basic insights and application for commodity production from methanol.
Topics: Bacillus; DNA, Bacterial; Genome, Bacterial; Glutamic Acid; Hot Temperature; Lysine; Methanol; Plasmids; Promoter Regions, Genetic; Proteome; Proteomics; Sequence Analysis, DNA | 2015 |
Comparison of Carisolv system vs traditional rotating instruments for caries removal in the primary dentition: A systematic review and meta-analysis.
Topics: Anesthesia, Local; Dental Caries; Dental Cavity Preparation; Glutamic Acid; Humans; Leucine; Lysine; Reproducibility of Results; Time Factors; Tooth, Deciduous; Treatment Outcome | 2015 |
Production of amino acids - Genetic and metabolic engineering approaches.
Topics: Amino Acids; Corynebacterium glutamicum; Genetic Engineering; Glutamic Acid; Lysine; Metabolic Engineering | 2017 |
Efficient cell factories for the production of N-methylated amino acids and for methanol-based amino acid production.
Topics: Amino Acids; Corynebacterium glutamicum; Glutamic Acid; Lysine; Metabolic Engineering; Methanol | 2022 |
A Bibliometric Analysis (2010-2020) of the Dental Scientific Literature on Chemo-Mechanical Methods of Caries Removal Using Carisolv and BRIX3000.
Topics: Bibliometrics; Child; Dental Caries; Dental Caries Susceptibility; Glutamic Acid; Humans; Leucine; Lysine | 2022 |
Review: Organophosphorus toxicants, in addition to inhibiting acetylcholinesterase activity, make covalent adducts on multiple proteins and promote protein crosslinking into high molecular weight aggregates.
Topics: Acetylcholinesterase; Animals; Glutamic Acid; Humans; Lysine; Molecular Weight; Neuroblastoma; Organophosphorus Compounds; Pesticides; Proteins; Rabbits; Tyrosine | 2023 |
34 trial(s) available for glutamic acid and lysine
| Article | Year |
|---|---|
Removal of carious dentin by Er:YAG laser irradiation with and without carisolv.
Topics: Dental Caries; Dental Cavity Preparation; Dentin; Glutamic Acid; Humans; Laser Therapy; Leucine; Lysine; Microscopy, Electron, Scanning | 2001 |
Clinical evaluation of the Carisolv chemomechanical caries removal technique according to the site/stage concept, a revised caries classification system.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, Dental; Child; Dental Caries; Dental Cavity Preparation; Dentin; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Middle Aged; Patient Satisfaction; Prospective Studies; Surveys and Questionnaires; Time Factors | 2003 |
A comparative clinical study on the Carisolv caries removal method.
Topics: Adolescent; Adult; Dental Caries; Dental Cavity Preparation; Dental Restoration, Permanent; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Middle Aged; Patient Satisfaction; Surveys and Questionnaires; Task Performance and Analysis | 2003 |
Interfacial micromorphology of three adhesive systems created in caries-affected dentin.
Topics: Composite Resins; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Restoration, Permanent; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; Leucine; Lysine; Methacrylates; Microscopy, Electron, Scanning; Phosphoric Acids; Resin Cements; Sodium Hypochlorite; Stress, Mechanical; Surface Properties | 2003 |
Evaluation of the chemomechanical removal of dentine caries in vivo with a new modified Carisolv gel.
Topics: Adult; Aged; Aged, 80 and over; Dental Caries; Dental Cavity Preparation; Dentin; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Middle Aged; Patient Satisfaction; Surveys and Questionnaires; Time Factors | 2004 |
An in vitro investigation of microtensile bond strengths of two dentine adhesives to caries-affected dentine.
Topics: Adhesiveness; Adult; Composite Resins; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Restoration, Permanent; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Methacrylates; Microscopy, Electron, Scanning; Polymethacrylic Acids; Surface Properties; Tensile Strength | 2005 |
Removing dentine caries in deciduous teeth with Carisolv: a randomised, controlled, prospective study with six-month follow-up, comparing chemomechanical treatment with drilling.
Topics: Chi-Square Distribution; Child; Child, Preschool; Dental Caries; Dental Cavity Preparation; Dentin; Female; Follow-Up Studies; Glutamic Acid; Humans; Leucine; Lysine; Male; Patient Satisfaction; Prospective Studies; Statistics, Nonparametric; Tooth, Deciduous | 2005 |
Chemomechanical caries removal for children.
Topics: Anesthesia, Dental; Child; Child, Preschool; Dental Care for Children; Dental Caries; Dental Cavity Preparation; Dental Instruments; Dental Restoration, Permanent; Dentition, Permanent; DMF Index; Glutamic Acid; Humans; Leucine; Lysine; Pain; Tooth, Deciduous; Treatment Outcome | 2005 |
Clinical randomized controlled trial of chemomechanical caries removal (Carisolv).
Topics: Anesthesia, Local; Child; Child Behavior; Cross-Over Studies; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Molar; Pain; Patient Satisfaction; Time Factors; Tooth, Deciduous; Treatment Outcome | 2006 |
Scanning electron microscopic analysis of the effect of Carisolv gel on periodontally compromised human root surfaces.
Topics: Analysis of Variance; Dental Scaling; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Root Planing; Smear Layer; Surface Properties; Tooth Root | 2006 |
Clinical evaluation of chemomechanical and mechanical caries removal: status of the restorations at 3, 6, 9 and 12 months.
Topics: Chi-Square Distribution; Child, Preschool; Compomers; Dental Caries; Dental Cavity Preparation; Dental Instruments; Dental Marginal Adaptation; Dental Restoration, Permanent; Dentin; Female; Follow-Up Studies; Glutamic Acid; Humans; Leucine; Lysine; Male; Pain Measurement; Prospective Studies; Time Factors; Tooth, Deciduous | 2007 |
Chemomechanical caries removal in children: efficacy and efficiency.
Topics: Bisphenol A-Glycidyl Methacrylate; Child; Dental Care for Children; Dental Caries; Dental Cavity Preparation; Dental High-Speed Technique; Dental Restoration, Permanent; Dentin; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Molar; Prospective Studies; Time Factors; Tooth, Deciduous | 2006 |
Iatrogenic damage to the adjacent surfaces of primary molars, in three different ways of cavity preparation.
Topics: Child; Dental Caries; Dental Cavity Preparation; Dental Enamel; Dental High-Speed Equipment; Dentin; Diamond; Glutamic Acid; Humans; Iatrogenic Disease; Leucine; Lysine; Models, Dental; Molar; Stainless Steel; Tooth, Deciduous | 2006 |
Residual caries and marginal integrity in relation to Class II glass ionomer restorations in primary molars.
Topics: Child; Child Behavior; Clinical Competence; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Dental Instruments; Dental Leakage; Dental Marginal Adaptation; Dental Restoration, Permanent; Female; Glass Ionomer Cements; Glutamic Acid; Humans; Leucine; Lysine; Male; Molar; Recurrence; Tooth Cervix; Tooth, Deciduous | 2006 |
Influence of residual caries and cervical gaps on the survival rate of Class II glass ionomer restorations.
Topics: Child; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Dental Instruments; Dental Marginal Adaptation; Dental Restoration Failure; Dental Restoration, Permanent; Female; Glass Ionomer Cements; Glutamic Acid; Humans; Leucine; Lysine; Male; Recurrence; Tooth Cervix | 2006 |
Efficacy of Carisolv as an adjunctive therapy to scaling and root planing on subgingival calculus removal.
Topics: Adult; Dental Calculus; Dental Scaling; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Leucine; Lysine; Male; Photography, Dental; Placebos; Root Planing; Solvents; Time Factors; Treatment Outcome | 2006 |
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.
Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Female; Genetic Variation; Genotype; Glutamic Acid; Glycine; Haplotypes; Humans; Ibuprofen; Leucine; Lysine; Male; Methionine; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Racemases and Epimerases; Rectal Neoplasms; Serine; Valine | 2007 |
Analysis of surface roughness and microleakage of fissure sealants following organic debris removal with Carisolv.
Topics: Acid Etching, Dental; Dental Bonding; Dental Cavity Preparation; Dental Deposits; Dental Enamel; Dental Fissures; Dental Leakage; Dental Marginal Adaptation; Glutamic Acid; Humans; Imaging, Three-Dimensional; Leucine; Lysine; Materials Testing; Microscopy, Confocal; Microscopy, Electron, Scanning; Pit and Fissure Sealants; Smear Layer; Toothbrushing | 2008 |
The association of ENPP1 K121Q with diabetes incidence is abolished by lifestyle modification in the diabetes prevention program.
Topics: Chromans; Combined Modality Therapy; Diabetes Mellitus, Type 2; Exercise Therapy; Female; Gene Frequency; Genetic Linkage; Genetic Predisposition to Disease; Glutamic Acid; Humans; Hypoglycemic Agents; Incidence; Lysine; Male; Metformin; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Pyrophosphatases; Risk Reduction Behavior; Thiazolidinediones; Troglitazone | 2009 |
Two years survival rate of class II composite resin restorations prepared by ART with and without a chemomechanical caries removal gel in primary molars.
Topics: Cariostatic Agents; Child; Composite Resins; Dental Caries; Dental Cavity Preparation; Dental Restoration Failure; Dental Restoration, Permanent; Female; Glutamic Acid; Humans; Kaplan-Meier Estimate; Leucine; Lysine; Male; Minimally Invasive Surgical Procedures; Molar; Resin Cements; Tooth, Deciduous | 2009 |
Clinical evaluation of a chemomechanical method for caries removal in children and adolescents.
Topics: Acid Etching, Dental; Adolescent; Anesthesia, Dental; Anesthesia, Local; Child; Child, Preschool; Composite Resins; Dental Amalgam; Dental Caries; Dental Cavity Preparation; Dental Materials; Dental Restoration, Permanent; Dentin; Female; Follow-Up Studies; Glass Ionomer Cements; Glutamic Acid; Humans; Leucine; Lysine; Male; Pain Measurement; Patient Preference; Patient Satisfaction; Prospective Studies; Resin Cements; Time Factors; Treatment Outcome | 2009 |
Evaluation of different fluoride treatments of initial root carious lesions in vivo.
Topics: Adult; Aged; Aged, 80 and over; Cariostatic Agents; Colony Count, Microbial; Dental Cavity Preparation; Dental Plaque; Dentin; Female; Fluorides, Topical; Follow-Up Studies; Glutamic Acid; Humans; Leucine; Lysine; Male; Middle Aged; Prospective Studies; Root Caries; Saliva; Single-Blind Method; Sodium Fluoride; Streptococcus mutans; Tin Fluorides; Tooth Remineralization; Treatment Outcome | 2009 |
KCNJ11 Lys23Glu and TCF7L2 rs290487(C/T) polymorphisms affect therapeutic efficacy of repaglinide in Chinese patients with type 2 diabetes.
Topics: Adult; Alleles; Amino Acid Substitution; Asian People; Blood Glucose; Carbamates; Diabetes Mellitus, Type 2; Female; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Piperidines; Polymorphism, Genetic; Potassium Channels, Inwardly Rectifying; Risk Factors; TCF Transcription Factors; Transcription Factor 7-Like 2 Protein; Treatment Outcome | 2010 |
An in vitro evaluation of microtensile bond strengths of two adhesive bonding agents to residual dentine after caries removal using three excavation techniques.
Topics: Acid Etching, Dental; Adhesiveness; Composite Resins; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Materials; Dental Restoration, Permanent; Dental Stress Analysis; Dentin; Dentin-Bonding Agents; Fluorescence; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Confocal; Microscopy, Electron, Scanning; Molar; Optical Fibers; Pepsin A; Resin Cements; Smear Layer; Stress, Mechanical; Surface Properties; Tensile Strength; Water | 2010 |
Caries-removal effectiveness and minimal-invasiveness potential of caries-excavation techniques: a micro-CT investigation.
Topics: Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Dentin; Diamond; Equipment Design; Feedback; Fluorescence; Fluorescent Dyes; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lasers, Solid-State; Leucine; Lysine; Materials Testing; Minerals; Molar; Propylene Glycols; Rhodamines; Tungsten Compounds; X-Ray Microtomography | 2011 |
Removal of organic debris from occlusal fissures: advantage of Carisolv system over sodium hypochlorite.
Topics: Dental Deposits; Dental Enamel; Dental Leakage; Detergents; Fluorescent Dyes; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Pit and Fissure Sealants; Rhodamines; Safety; Sodium Hypochlorite; Temperature; Time Factors | 2010 |
Facial skin-lightening benefits of the tetrapeptide Pro-Lys-Glu-Lys on subjects with skin types V-VI living in South Africa.
Topics: Adult; Dermatologic Agents; Double-Blind Method; Face; Female; Glutamic Acid; Humans; Lysine; Melanosis; Middle Aged; Oligopeptides; Proline; Skin Pigmentation; South Africa; Treatment Outcome | 2011 |
Permeability evaluation after decay removal in primary teeth with current caries-excavation techniques.
Topics: Coloring Agents; Composite Resins; Dental Caries; Dental Cavity Preparation; Dental Leakage; Dental Materials; Dental Restoration, Permanent; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Microscopy, Electron, Scanning; Molar; Permeability; Resin Cements; Surface Properties; Temperature; Time Factors; Tooth, Deciduous; Water | 2011 |
Evaluation of micro-tensile bond strength of caries-affected human dentine after three different caries removal techniques.
Topics: Acid Etching, Dental; Composite Resins; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Cements; Dental Stress Analysis; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; Laser Therapy; Lasers, Solid-State; Leucine; Lysine; Materials Testing; Methacrylates; Microscopy, Electron, Scanning; Resin Cements; Smear Layer; Stress, Mechanical; Temperature; Tensile Strength; Time Factors; Water | 2012 |
An evaluation of different caries removal techniques in primary teeth: a comparitive clinical study.
Topics: Analysis of Variance; Child; Child, Preschool; Dental Caries; Dental Cavity Preparation; Dental High-Speed Technique; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Pain Measurement; Papain; Tooth, Deciduous | 2011 |
Chemomechanical caries removal in primary molars : evaluation of marginal leakage and shear bond strength in bonded restorations--an in vitro study.
Topics: Coloring Agents; Composite Resins; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Enamel; Dental Leakage; Dental Materials; Dental Restoration, Permanent; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Molar; Papain; Rosaniline Dyes; Shear Strength; Sodium Chloride; Stress, Mechanical; Temperature; Time Factors; Tooth, Deciduous; Water | 2013 |
Effect of caries removal techniques on the bond strength of adhesives to caries-affected primary dentin in vitro.
Topics: Adhesiveness; Composite Resins; Curettage; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Cements; Dental High-Speed Equipment; Dental Materials; Dental Restoration, Permanent; Dental Stress Analysis; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; Laser Therapy; Lasers, Solid-State; Leucine; Lysine; Materials Testing; Methacrylates; Microscopy, Electron, Scanning; Molar; Steel; Stress, Mechanical; Surface Properties; Tensile Strength; Tooth, Deciduous | 2013 |
Efficacy of chemomechanical caries removal in reducing cariogenic microbiota: a randomized clinical trial.
Topics: Child; Child, Preschool; Colony Count, Microbial; Dental Caries; Dental Cavity Preparation; Dentin; Female; Glutamic Acid; Humans; Lactobacillus; Leucine; Lysine; Male; Papain; Statistics, Nonparametric; Streptococcus mutans; Treatment Outcome | 2014 |
Reduction in Bacterial Loading using Papacarie and Carisolv as an Irrigant in Pulpectomized Primary Molars - A Preliminary Report.
Topics: Child; Child, Preschool; Dental Pulp Cavity; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Molar; Papain; Root Canal Irrigants; Root Canal Preparation; Sodium Hypochlorite | 2020 |
1038 other study(ies) available for glutamic acid and lysine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Synthesis and structure-activity relationships of some pesticides with an alpha-amino acid function.
Topics: Amino Acids; Drug Carriers; Hydrogen-Ion Concentration; Lysine; Membrane Potentials; Pesticides; Solubility; Structure-Activity Relationship; Threonine | 1997 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis | 2002 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Design, synthesis and biological evaluation of novel nitroaromatic compounds as potent glutathione reductase inhibitors.
Topics: Chemistry Techniques, Synthetic; Crystallography, X-Ray; Dinitrobenzenes; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Glutathione Reductase; Humans; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2011 |
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Topics: Amino Acid Transport Systems; Antiporters; Escherichia coli Proteins; HEK293 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Molecular Docking Simulation; Phenylalanine; Stereoisomerism; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2018 |
Overproduced rho factor from p39AS has lysine replacing glutamic acid at residue 155 in the linker region between its RNA and ATP binding domains.
Topics: Adenosine Triphosphate; Binding Sites; Cloning, Molecular; Glutamates; Glutamic Acid; Lysine; Mutation; Plasmids; Rho Factor; RNA | 1992 |
Probing the active site of the reconstituted aspartate/glutamate carrier from bovine heart mitochondria: carbodiimide-catalyzed acylation of a functional lysine residue.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Acylation; Amino Acid Transport Systems, Acidic; Animals; Antiporters; Aspartic Acid; Binding Sites; Biological Transport; Carrier Proteins; Catalysis; Cattle; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Ethyldimethylaminopropyl Carbodiimide; Glutamates; Glutamic Acid; Kinetics; Lysine; Mitochondria, Heart; Proteolipids; Pyridoxal Phosphate | 1992 |
Different positively charged amino acids have similar effects on the topology of a polytopic transmembrane protein in Escherichia coli.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Cell Membrane; Endopeptidases; Escherichia coli; Glutamates; Glutamic Acid; Lysine; Membrane Proteins; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Protein Conformation; Serine Endopeptidases | 1992 |
Are proton symports in yeast directly linked to H(+)-ATPase acidification?
Topics: Deuterium; Diethylstilbestrol; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Leucine; Lysine; Membrane Potentials; Proton-Translocating ATPases; Protons; Saccharomyces cerevisiae; Suloctidil | 1992 |
Two alloalbumins with identical electrophoretic mobility are produced by differently charged amino acid substitutions.
Topics: Amino Acid Sequence; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Genetic Variation; Glutamates; Glutamic Acid; Humans; Isoelectric Focusing; Lysine; Molecular Sequence Data; Mutation; Serum Albumin | 1992 |
Effects of dietary level of lysine and of level and source of protein on feed intake, growth performance, and plasma amino acid pattern in the finishing pig.
Topics: Adipose Tissue; Amino Acids; Animal Feed; Animals; Body Composition; Dietary Proteins; Eating; Female; Glutamates; Glutamic Acid; Lysine; Male; Muscle Development; Random Allocation; Sex Characteristics; Swine; Weight Gain | 1992 |
Heterozygosity for apolipoprotein E-4Philadelphia(Glu13----Lys, Arg145----Cys) is associated with incomplete dominance of type III hyperlipoproteinemia.
Topics: Adolescent; Adult; Aged; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E; Arginine; Child; Cysteine; DNA; Electrophoresis, Polyacrylamide Gel; Female; Genes, Dominant; Glutamates; Glutamic Acid; Heterozygote; Homozygote; Humans; Hyperlipoproteinemia Type III; Lysine; Male; Middle Aged; Pedigree; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 1992 |
Characterization of two new point mutations in the low density lipoprotein receptor genes of an English patient with homozygous familial hypercholesterolemia.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Cells, Cultured; Child, Preschool; England; Exons; Glutamates; Glutamic Acid; Homozygote; Humans; Hyperlipoproteinemia Type II; Lysine; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Pedigree; Phenotype; Receptors, LDL | 1992 |
Free amino acid dynamics in marine methanogens. beta-Amino acids as compatible solutes.
Topics: Amino Acids; Anions; Betaine; Euryarchaeota; Glutamates; Glutamic Acid; Lysine; Magnetic Resonance Spectroscopy; Osmolar Concentration; Potassium; Spectrophotometry, Atomic | 1992 |
Faster superoxide dismutase mutants designed by enhancing electrostatic guidance.
Topics: Amino Acid Sequence; Computer Simulation; Electrochemistry; Glutamates; Glutamic Acid; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Superoxide Dismutase | 1992 |
Proton transfer roles of lysine 64 and glutamic acid 64 replacing histidine 64 in the active site of human carbonic anhydrase II.
Topics: Binding Sites; Buffers; Carbonic Anhydrases; Cloning, Molecular; Escherichia coli; Glutamates; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Plasmids; Protons | 1992 |
Thialysine-resistant mutants and uptake of lysine in Schizosaccharomyces pombe.
Topics: Arginine; Biological Transport, Active; Cysteine; Drug Resistance, Microbial; Glutamates; Glutamic Acid; Kinetics; Leucine; Lysine; Schizosaccharomyces | 1992 |
Constitutively active mutants of rhodopsin.
Topics: Amino Acid Sequence; Animals; Cell Line; Glutamates; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Retinaldehyde; Rhodopsin; Rod Cell Outer Segment; Rod Opsins; Schiff Bases; Transducin; Transfection | 1992 |
GAA(Glu)272----AAA(Lys) and CGA(Arg)1941----CAA(Gln) in the factor VIII gene in two haemophilia A patients of Czech origin.
Topics: Amino Acid Sequence; Arginine; Base Sequence; Czechoslovakia; DNA; Factor VIII; Glutamates; Glutamic Acid; Hemophilia A; Humans; Lysine; Polymerase Chain Reaction; White People | 1992 |
Apolipoprotein E1 Lys-146----Glu with type III hyperlipoproteinemia.
Topics: Adult; Amino Acid Sequence; Apolipoprotein E2; Apolipoproteins E; Base Sequence; Child; DNA; Electrophoresis, Gel, Two-Dimensional; Female; Genetic Carrier Screening; Glutamates; Glutamic Acid; Humans; Hyperlipoproteinemia Type III; Lysine; Male; Middle Aged; Molecular Sequence Data; Oligodeoxyribonucleotides; Pedigree; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 1992 |
The A14 position of insulin tolerates considerable structural alterations with modest effects on the biological behavior of the hormone.
Topics: Adipose Tissue; Alanine; Amino Acids; Animals; Cattle; Cycloleucine; Glucose; Glutamates; Glutamic Acid; Histidine; Insulin; Lipids; Liver; Lysine; Phenylalanine; Rats; Receptor, Insulin; Sheep; Structure-Activity Relationship; Swine; Tyrosine | 1992 |
Regulation of rat erythrocyte L-glutamine, L-glutamate and L-lysine uptake by short term starvation.
Topics: Animals; Erythrocytes; Female; Glutamates; Glutamic Acid; Glutamine; Kinetics; Lysine; Rats; Rats, Wistar; Starvation | 1992 |
The subcellular distribution of nickel in Ni-sensitive and Ni-resistant strains of Saccharomyces cerevisiae.
Topics: Amino Acids; Drug Resistance, Microbial; Glutamates; Glutamic Acid; Histidine; Lysine; Nickel; Saccharomyces cerevisiae; Vacuoles | 1992 |
Impaired tetramer assembly of variant medium-chain acyl-coenzyme A dehydrogenase with a glutamate or aspartate substitution for lysine 304 causing instability of the protein.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Alleles; Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Chromatography, Gel; Cloning, Molecular; Codon; Enzyme Stability; Genetic Variation; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Macromolecular Substances; Mitochondria, Liver; Polymerase Chain Reaction; Protein Biosynthesis; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Transcription, Genetic | 1992 |
Mutational analysis of centrin: an EF-hand protein associated with three distinct contractile fibers in the basal body apparatus of Chlamydomonas.
Topics: Animals; Base Sequence; Calcium-Binding Proteins; Cell Nucleus; Chlamydomonas reinhardtii; Chromosomal Proteins, Non-Histone; Contractile Proteins; DNA Mutational Analysis; Flagella; Fluorescent Antibody Technique; Glutamates; Glutamic Acid; Lysine; Microscopy, Immunoelectron; Molecular Sequence Data; Morphogenesis; Mutagenesis, Site-Directed; Organelles; Polymorphism, Restriction Fragment Length; Protein Conformation; Protein Structure, Secondary; Spindle Apparatus; Structure-Activity Relationship | 1992 |
[The effect of acute poisoning of rats with carbaryl on the transamination reactions involving alpha-ketoglutarate. Part I. Activity of plasma aminotransferases].
Topics: Animals; Carbaryl; Glutamate Synthase; Glutamates; Glutamic Acid; Ketoglutaric Acids; Lysine; Male; Rats; Rats, Wistar | 1992 |
Change of glutamic acid to lysine in a 13-residue antibacterial and hemolytic peptide results in enhanced antibacterial activity without increase in hemolytic activity.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Erythrocytes; Escherichia coli; Glutamates; Glutamic Acid; Hemolysis; Hydrogen-Ion Concentration; Kinetics; Lysine; Membrane Potentials; Molecular Sequence Data; Peptide Fragments; Peptides; Proteins; Rats; Seminal Vesicle Secretory Proteins; Structure-Activity Relationship | 1992 |
Effects of 2-deoxy-D-glucose on the glucose metabolism in Saccharomyces cerevisiae studied by multinuclear-NMR spectroscopy and biochemical methods.
Topics: Alanine; Arginine; Citric Acid Cycle; Deoxyglucose; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glutamates; Glutamic Acid; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Phosphorylation; Polyphosphates; Saccharomyces cerevisiae | 1992 |
Sodium ion-dependent amino acid transport in membrane vesicles of Bacillus stearothermophilus.
Topics: Alanine; Allosteric Site; Amino Acids; Anti-Bacterial Agents; Binding, Competitive; Biological Transport; Cell Membrane; Geobacillus stearothermophilus; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Ionophores; Kinetics; Leucine; Lysine; Macrolides; Monensin; Sodium | 1991 |
Receptor sites for amino acids in the facial taste system of the channel catfish.
Topics: Action Potentials; Adaptation, Physiological; Alanine; Animals; Arginine; Electrophysiology; Glutamates; Glutamic Acid; Histidine; Ictaluridae; Lysine; Methionine; Proline; Receptors, Amino Acid; Receptors, Cell Surface; Stereoisomerism; Taste | 1991 |
A single nucleotide substitution in the D domain of estrogen receptor cDNA causes amino acid alteration from Glu-279 to Lys-279 in a murine transformed Leydig cell line (B-1 F).
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line, Transformed; Chickens; Glutamates; Glutamic Acid; Humans; Leydig Cells; Lysine; Male; Mammary Neoplasms, Experimental; Mice; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured | 1991 |
Characterization of the binding of plasminogen to fibrin surfaces: the role of carboxy-terminal lysines.
Topics: Antibodies; Binding Sites; Electrophoresis; Fibrin; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Plasminogen; Radioligand Assay | 1991 |
Activation of excitatory amino acid receptors cannot alone account for anoxia-induced impairment of protein synthesis in rat hippocampal slices.
Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; Hypoxia; Kainic Acid; Lysine; Male; N-Methylaspartate; Nerve Tissue Proteins; Phenazocine; Phencyclidine; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Human erythrocyte band 3 polymorphism (band 3 Memphis): characterization of the structural modification (Lys 56----Glu) by protein chemistry methods.
Topics: Anion Exchange Protein 1, Erythrocyte; Chymotrypsin; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Heterozygote; Humans; Lysine; Peptide Fragments; Peptide Mapping; Polymorphism, Genetic; Serine Endopeptidases; Stilbenes; Trypsin | 1991 |
The effects of surface charges on the redox potential of cytochrome c2 from the purple phototrophic bacterium Rhodobacter capsulatus.
Topics: Aspartic Acid; Cytochrome c Group; Cytochromes c2; Electrochemistry; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Isoelectric Point; Lysine; Mutagenesis; Osmolar Concentration; Oxidation-Reduction; Rhodobacter capsulatus | 1991 |
Conversion of lysine 91 to methionine or glutamic acid in human choriogonadotropin alpha results in the loss of cAMP inducibility.
Topics: Animals; Cell Line; Chorionic Gonadotropin; Cricetinae; Cricetulus; Cyclic AMP; DNA; Gene Expression; Glutamates; Glutamic Acid; Lysine; Methionine; Mice; Mutation; Radioimmunoassay; Swine; Transfection; Tumor Cells, Cultured | 1991 |
Cerebellar ataxia with glutamic aciduria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Arginine; Atrophy; Cerebellum; Cystinuria; Female; Glutamates; Glutamic Acid; Humans; Kidney Tubules; Lysine; Magnetic Resonance Imaging; Ornithine; Spinocerebellar Degenerations | 1991 |
The route of lysine breakdown in Candida tropicalis.
Topics: Acetates; Acetic Acid; Acetyltransferases; Candida; Glutamates; Glutamic Acid; Kinetics; Lysine; Rhodotorula; Temperature; Transaminases | 1991 |
Structure and function of neurons in the complex of the nucleus electrosensorius of the gymnotiform fish Eigenmannia: detection and processing of electric signals in social communication.
Topics: Aggression; Animal Communication; Animals; Diencephalon; Electric Fish; Electrodes; Female; Glutamates; Glutamic Acid; Horseradish Peroxidase; Hypothalamus; Lysine; Male; Mechanoreceptors; Neurons; Neurons, Afferent; Sexual Behavior, Animal; Social Behavior | 1991 |
Functional and ultrastructural effects of a missense mutation in the indirect flight muscle-specific actin gene of Drosophila melanogaster.
Topics: Actins; Amino Acid Sequence; Animals; Cloning, Molecular; Drosophila melanogaster; Flight, Animal; Glutamates; Glutamic Acid; Lysine; Microscopy, Electron; Muscle Proteins; Muscle Relaxation; Muscles; Mutation; Myofibrils; Peptide Mapping | 1991 |
Nature of the HABA binding to human serum albumin.
Topics: Amino Acid Sequence; Azo Compounds; Binding Sites; Fluorescent Dyes; Glutamates; Glutamic Acid; Humans; Ligands; Lysine; Protein Binding; Protein Conformation; Serum Albumin | 1991 |
Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residue.
Topics: Animals; Cells, Cultured; Enzyme Activation; Fibroblast Growth Factor 1; Gene Expression Regulation; Glutamates; Glutamic Acid; Heparin; Lysine; Mitosis; Mutagenesis, Site-Directed; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Cell Surface; Receptors, Fibroblast Growth Factor; RNA, Messenger; Transfection | 1990 |
Role of lysine-67 in the active site of class C beta-lactamase from Citrobacter freundii GN346.
Topics: Amino Acid Sequence; Arginine; Base Sequence; beta-Lactamases; Binding Sites; Cephalosporinase; Citrobacter; Escherichia coli; Genes, Bacterial; Glutamates; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Protein Engineering; Restriction Mapping; RNA, Messenger; Threonine | 1990 |
Examination of the intersubunit interaction between glutamate-48 and lysine-168 of ribulose-bisphosphate carboxylase/oxygenase by site-directed mutagenesis.
Topics: Base Sequence; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Glutamates; Glutamic Acid; Kinetics; Lysine; Macromolecular Substances; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Plasmids; Rhodospirillum rubrum; Ribulose-Bisphosphate Carboxylase | 1990 |
Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu).
Topics: Alanine; Enzyme Activation; Enzyme Precursors; Escherichia coli; Fibrinolysin; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mutation; Plasminogen; Plasminogen Activators; Recombinant Proteins; Serine; Urokinase-Type Plasminogen Activator | 1990 |
Recurrent mutation in the human phenylalanine hydroxylase gene.
Topics: Alleles; Base Sequence; DNA; Female; Genes; Genetic Carrier Screening; Glutamates; Glutamic Acid; Haplotypes; Humans; Leukocytes; Lysine; Male; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Pedigree; Phenylalanine Hydroxylase; Phenylketonurias; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Restriction Mapping | 1990 |
Substitution of aspartic acid-217 of Citrobacter freundii cephalosporinase and properties of the mutant enzymes.
Topics: Aspartic Acid; beta-Lactamases; Cephalosporinase; Citrobacter; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glutamates; Glutamic Acid; Kinetics; Lysine; Mutation; Substrate Specificity; Threonine | 1990 |
Studies on the regulatory domain of Ca2+/calmodulin-dependent protein kinase II. Functional analyses of arginine 283 using synthetic inhibitory peptides and site-directed mutagenesis of the alpha subunit.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Arginine; Base Sequence; Binding Sites; Binding, Competitive; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; DNA; Egtazic Acid; Glutamates; Glutamic Acid; Glutamine; Immunosorbent Techniques; Kinetics; Lysine; Mice; Molecular Sequence Data; Mutation; Peptide Fragments; Phenylglyoxal; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rats | 1990 |
The molecular defect of albumin Castel di Sangro: 536 Lys----Glu.
Topics: Chromatography, High Pressure Liquid; Cyanogen Bromide; Genetic Variation; Glutamates; Glutamic Acid; Humans; Lysine; Mutation; Peptide Fragments; Serum Albumin; Serum Albumin, Human; Trypsin | 1990 |
Molecular defect (Gla+14----Lys) and its functional consequences in a hereditary factor X deficiency (factor X "Vorarlberg").
Topics: Amino Acid Sequence; Base Sequence; Calcium; Exons; Factor X; Factor X Deficiency; Female; Glutamates; Glutamic Acid; Humans; Hypoprothrombinemias; Kinetics; Lysine; Male; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Pedigree; Reference Values | 1990 |
A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; DNA, Bacterial; Escherichia coli; Glutamates; Glutamic Acid; Hot Temperature; Inorganic Pyrophosphatase; Lysine; Molecular Sequence Data; Mutation; Pyrophosphatases; Solubility; Structure-Activity Relationship | 1990 |
The role of lysine-234 in beta-lactamase catalysis probed by site-directed mutagenesis.
Topics: Alanine; Bacillus; Base Sequence; beta-Lactamases; Catalysis; DNA, Bacterial; Gene Expression; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutation; Penicillin V; Substrate Specificity | 1990 |
Changes in membrane lipids and amino acid transport in a nystatin-resistant Aspergillus niger.
Topics: Amino Acids; Aspergillus niger; Biological Transport; Drug Resistance, Microbial; Fatty Acids; Glutamates; Glutamic Acid; Leucine; Linoleic Acids; Lysine; Membrane Lipids; Mutation; Nystatin; Phospholipids | 1990 |
Inhibition of alpha-aminoadipate-semialdehyde dehydrogenase from Trichosporon adeninovorans by lysine and lysine analogues.
Topics: Aldehyde Oxidoreductases; Binding, Competitive; Cysteine; Glutamates; Glutamic Acid; Hydroxylysine; Kinetics; L-Aminoadipate-Semialdehyde Dehydrogenase; Lysine; Mitosporic Fungi; Trichosporon | 1990 |
Stimulatory actions of bioflavonoids on tyrosine uptake into cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Biological Transport; Carbon Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chamomile; Flavones; Flavonoids; Glutamates; Glutamic Acid; Histidine; Lysine; Oils, Volatile; Plants, Medicinal; Quercetin; Serine; Tyrosine | 1990 |
Lys-65 and Glu-168 are the residues for carbodiimide-catalyzed cross-linking between the two heads of rigor smooth muscle heavy meromyosin.
Topics: Actins; Amino Acid Sequence; Animals; Chickens; Cross-Linking Reagents; Ethyldimethylaminopropyl Carbodiimide; Gizzard, Avian; Glutamates; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Weight; Muscle, Smooth; Muscles; Myosin Subfragments; Peptide Fragments; Protein Conformation; Rabbits | 1990 |
Site-directed mutagenesis of beta-lactamase I. Single and double mutants of Glu-166 and Lys-73.
Topics: Bacillus cereus; Cephalosporins; Escherichia coli; Glutamates; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Mutagenesis, Site-Directed; Penicillin G; Penicillinase; Substrate Specificity | 1990 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Aspartyl- and glutamyl-lysine crosslinks formation and their nutritional availability.
Topics: Animals; Aspartic Acid; Biological Availability; Cross-Linking Reagents; Digestion; Dipeptidases; gamma-Glutamylcyclotransferase; Gliadin; Glutamates; Glutamic Acid; Intestinal Absorption; Kidney; Lysine; Nutritive Value; Peptide Hydrolases; Rats; Transglutaminases; Triticum | 1990 |
Cationic and anionic amino acid transport studies in rat red blood cells.
Topics: Alanine; Animals; Biological Transport; Dose-Response Relationship, Drug; Erythrocytes; Female; Glutamates; Glutamic Acid; Lysine; Proline; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Isolation and characterization of 15K noncollagenous protein from bovine periodontal ligament.
Topics: Alanine; Animals; Aspartic Acid; Cattle; Chromatography, Gel; Enzyme-Linked Immunosorbent Assay; Glutamates; Glutamic Acid; Leucine; Lysine; Periodontal Ligament; Protein Biosynthesis; Proteins; Radioimmunoassay | 1990 |
Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant.
Topics: Aldehyde Dehydrogenase; Alleles; Ethanol; Gene Amplification; Genotype; Glutamates; Glutamic Acid; Humans; Liver; Lysine; Phenotype | 1989 |
Disruption of the 290-342 salt bridge is not responsible for the secretory defect of the PiZ alpha 1-antitrypsin variant.
Topics: alpha 1-Antitrypsin; Animals; Cell Line; Codon; DNA, Recombinant; Genetic Variation; Genetic Vectors; Glutamates; Glutamic Acid; Humans; Liver Neoplasms, Experimental; Lysine; Mice; Mutation; Simian virus 40; Transfection | 1989 |
Amino acid substitutions in albumin variants found in Brazil.
Topics: Amino Acid Sequence; Brazil; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyanogen Bromide; Electrophoresis, Starch Gel; Genetic Variation; Glutamates; Glutamic Acid; Hemoglobins, Abnormal; Humans; Lysine; Molecular Sequence Data; Peptide Fragments; Polymorphism, Genetic; Serum Albumin; Trypsin | 1989 |
Utilization of amino acids and peptides by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Culture Media; Fusobacterium; Glutamates; Glutamic Acid; Histidine; Lysine; Methionine; Peptides | 1989 |
Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study.
Topics: Amino Acid Sequence; Escherichia coli; Genes; Genes, Synthetic; Glutamates; Glutamic Acid; Hirudins; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Recombinant Proteins | 1989 |
Acanthamoeba actin and profilin can be cross-linked between glutamic acid 364 of actin and lysine 115 of profilin.
Topics: Acanthamoeba; Actins; Amino Acid Sequence; Animals; Contractile Proteins; Glutamates; Glutamic Acid; Lysine; Methionine; Microfilament Proteins; Molecular Sequence Data; Profilins; Trypsin | 1989 |
Effects of modifying individual amino or carboxyl groups on the affinity of calmodulin for calcineurin.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Binding, Competitive; Brain; Calcineurin; Calmodulin; Calmodulin-Binding Proteins; Cattle; Glutamates; Glutamic Acid; Kinetics; Lysine; Male; Mathematics; Models, Molecular; Molecular Sequence Data; Phosphoprotein Phosphatases; Protein Binding; Protein Conformation; Swine; Testis | 1989 |
Further characterization of the binding of plasminogen to heparin: evidence for the involvement of lysine residues.
Topics: Binding Sites; Borohydrides; Chemical Phenomena; Chemistry; Fibrinolysin; Glutamates; Glutamic Acid; Heparin; Humans; Lysine; Plasminogen; Pyridoxal Phosphate; Valine | 1989 |
Importance of amino acids on vasopressin-stimulated water flow.
Topics: Amino Acids; Animals; Bufonidae; Cyclic AMP; Diuresis; Drug Synergism; Female; Glutamates; Glutamic Acid; Histidine; Lysine; Methylation; Structure-Activity Relationship; Theophylline; Urinary Bladder; Vasopressins; Zinc | 1985 |
A new hemoglobin variant, Hb Mito [beta 144(HC 1) Lys----Glu], with increased oxygen affinity.
Topics: Amino Acid Sequence; Electrophoresis, Cellulose Acetate; Female; Glutamates; Glutamic Acid; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Hypertension; Isoelectric Focusing; Japan; Lysine; Middle Aged; Oxygen | 1985 |
Hemoglobin O-Padova or alpha(2)30(B11)Glu----Lys beta 2 observed in members of a Turkish family.
Topics: Adult; Amino Acids; Child; Chromatography, High Pressure Liquid; Electrophoresis, Starch Gel; Female; Glutamates; Glutamic Acid; Hemoglobins, Abnormal; Humans; Infant; Lysine; Male; Turkey | 1985 |
Cystine-glutamate transport interactions in rat renal cortical tubules, brushborder vesicles, and cultured renal tubule cells.
Topics: Animals; Biological Transport; Cell Membrane; Cells, Cultured; Culture Techniques; Cystine; Drug Interactions; Glutamates; Glutamic Acid; Kidney Cortex; Kidney Tubules; Lysine; Male; Microvilli; Rats; Rats, Inbred Strains | 1986 |
Effects of the phenylalanine-22----leucine, glutamic acid-49----methionine, glycine-234----aspartic acid, and glycine-234----lysine mutations on the folding and stability of the alpha subunit of tryptophan synthase from Escherichia coli.
Topics: Aspartic Acid; Drug Stability; Escherichia coli; Glutamates; Glutamic Acid; Glycine; Kinetics; Leucine; Lysine; Macromolecular Substances; Methionine; Mutation; Phenylalanine; Protein Conformation; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thermodynamics; Tryptophan Synthase | 1986 |
Biosynthesis of 5-methylaminomethyl-2-selenouridine, a naturally occurring nucleoside in Escherichia coli tRNA.
Topics: Chromatography, High Pressure Liquid; Escherichia coli; Glutamates; Glutamic Acid; Lysine; Organoselenium Compounds; RNA Processing, Post-Transcriptional; RNA, Transfer; Selenium; Sulfur; Uridine | 1986 |
Transport of acidic amino acids by human jejunal brush-border membrane vesicles.
Topics: Aspartic Acid; Biological Transport; Glutamates; Glutamic Acid; Humans; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Lysine; Microvilli; Stereoisomerism | 1987 |
Studies of the mechanism of glutamine synthetase utilizing pH-dependent behavior in catalysis and binding.
Topics: Adenosine Triphosphate; Amino Acids; Ammonia; Catalysis; Chemical Phenomena; Chemistry; Escherichia coli; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Homocysteine; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Lysine; Methionine Sulfoximine; Protons; Spectrometry, Fluorescence; Substrate Specificity; Sulfonamides | 1987 |
Disruption of the Lys-290--Glu-342 salt bridge in human alpha 1-antitrypsin does not prevent its synthesis and secretion.
Topics: alpha 1-Antitrypsin; Amino Acid Sequence; Animals; DNA; Female; Glutamates; Glutamic Acid; Humans; Lysine; Mutation; Oocytes; Protein Conformation; RNA, Messenger; Xenopus | 1987 |
Effects of lysine and glutamic acid or [corrected] Mg++ on the conformations of C3 and B, and the activation of the alternative complement pathway.
Topics: Binding Sites; Complement Activation; Complement C3; Complement Factor B; Complement Factor D; Complement Pathway, Alternative; Enzyme Precursors; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Lysine; Magnesium; Protein Conformation; Sodium; Spectrometry, Fluorescence | 1987 |
Effect of amino acid at the beta 6 position on surface hydrophobicity, stability, solubility, and the kinetics of polymerization of hemoglobin. Comparisons among Hb A (Glu beta 6), Hb C (Lys beta 6), Hb Machida (Gln beta 6), and Hb S (Val beta 6).
Topics: Drug Stability; Glutamates; Glutamic Acid; Glutamine; Hemoglobin A; Hemoglobin C; Hemoglobin, Sickle; Hemoglobins; Hemoglobins, Abnormal; Humans; Kinetics; Lysine; Macromolecular Substances; Oxyhemoglobins; Solubility; Structure-Activity Relationship; Valine | 1987 |
Enzymatic properties of single-chain and two-chain forms of a Lys158----Glu158 mutant of urokinase-type plasminogen activator.
Topics: Catalysis; Endopeptidases; Glutamates; Glutamic Acid; Lysine; Mutation; Plasminogen Activators; Recombinant Proteins; Staphylococcus aureus; Urokinase-Type Plasminogen Activator | 1988 |
Huntington's disease: studies on brain free amino acids.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Putamen; Serine; Taurine | 1988 |
The amino acid substitution in albumin Roma: 321 Glu----Lys.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cyanogen Bromide; Glutamates; Glutamic Acid; Heterozygote; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Lysine; Male; Mutation; Peptide Fragments; Serum Albumin; Serum Albumin, Human; Trypsin | 1988 |
A point mutation abolishes binding of cAMP to site A in the regulatory subunit of cAMP-dependent protein kinase.
Topics: Adenosine Monophosphate; Affinity Labels; Amino Acid Sequence; Animals; Arginine; Azides; Binding Sites; Cyclic AMP; DNA, Recombinant; Enzyme Activation; Escherichia coli; Glutamates; Glutamic Acid; Lysine; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Phosphates; Photochemistry; Protein Kinases; Swine | 1988 |
Site-directed mutagenesis of Petunia hybrida 5-enolpyruvylshikimate-3-phosphate synthase: Lys-23 is essential for substrate binding.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Alkyl and Aryl Transferases; Arginine; Binding Sites; Binding, Competitive; Glutamates; Glutamic Acid; Glycine; Glyphosate; Herbicides; Lysine; Mutation; Phosphoenolpyruvate; Plants; Pyridoxal Phosphate; Shikimic Acid; Transferases | 1988 |
The same substitution, glutamic acid----lysine at position 501, occurs in three alloalbumins of Asiatic origin: albumins Vancouver, Birmingham, and Adana.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Polymorphism, Genetic; Serum Albumin; Serum Albumin, Human | 1988 |
Mutational analysis of domain I of Pseudomonas exotoxin. Mutations in domain I of Pseudomonas exotoxin which reduce cell binding and animal toxicity.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Bacterial Adhesion; Bacterial Toxins; Binding, Competitive; Cell Survival; Exotoxins; Glutamates; Glutamic Acid; Lysine; Mice; Mutation; Pseudomonas aeruginosa Exotoxin A; Structure-Activity Relationship; Virulence Factors | 1988 |
Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.
Topics: Amino Acid Sequence; Animals; Endopeptidases; Enzyme Activation; Gastric Mucosa; Glutamates; Glutamic Acid; Humans; Isoenzymes; Lysine; Metalloendopeptidases; Molecular Sequence Data; Pepsinogens; Peptide Mapping | 1988 |
Repair of the secretion defect in the Z form of alpha 1-antitrypsin by addition of a second mutation.
Topics: alpha 1-Antitrypsin; alpha 1-Antitrypsin Deficiency; Animals; Cell Line; Codon; DNA; Electrochemistry; Endoplasmic Reticulum; Glutamates; Glutamic Acid; Humans; Lysine; Mutation; Protein Conformation; RNA, Messenger; Structure-Activity Relationship; Transfection | 1988 |
X-ray studies on crystalline complexes involving amino acids and peptides. XV. Crystal structures of L-lysine D-glutamate and L-lysine D-aspartate monohydrate and the effect of chirality on molecular aggregation.
Topics: Aspartic Acid; Crystallization; Dipeptides; Glutamates; Glutamic Acid; Hydrogen Bonding; Lysine; Molecular Structure; Protein Conformation; X-Ray Diffraction | 1988 |
Haemoglobin Hijiyama: a haemoglobin variant found in connection with glycosylated haemoglobin estimation in a Finnish diabetic boy.
Topics: Child; Colorimetry; Diabetes Mellitus; Electrophoresis; Glutamates; Glutamic Acid; Glycated Hemoglobin; Hemoglobin A; Hemoglobins, Abnormal; Humans; Isoelectric Focusing; Lysine; Male | 1982 |
Effect of amino acids on microbial production of citric acid by Aspergillus niger.
Topics: Amino Acids; Aspartic Acid; Aspergillus niger; Citrates; Citric Acid; Cysteine; Glutamates; Glutamic Acid; Lysine; Serine | 1982 |
Hemoglobin I (alpha 16(A14) Lys replaced by Glu) and hemoglobin J Iran (beta 77(EF1) His replaced by Asp) discovered in Japanese.
Topics: Aspartic Acid; Female; Globins; Glutamates; Glutamic Acid; Hemoglobin J; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Japan; Lysine; Male; Middle Aged | 1982 |
Activation pathway of glu-plasminogen to Lys-plasmin by urokinase.
Topics: Electrophoresis, Polyacrylamide Gel; Endopeptidases; Fibrinolysin; Glutamates; Glutamic Acid; Humans; Hydrolysis; Kinetics; Lysine; Oligopeptides; Plasminogen; Plasminogen Activators; Sodium Dodecyl Sulfate; Urokinase-Type Plasminogen Activator | 1982 |
Secondary effects of the ethionine-resistance mutation in Saccharomycopsis lipolytica.
Topics: Arginine; Ascomycota; Drug Resistance; Ethionine; Glutamates; Glutamic Acid; Glutamine; Glycolysis; Lysine; Methionine; Mutation; Saccharomycopsis | 1982 |
Transmembrane electrical potential in Rickettsia prowazekii and its relationship to lysine transport.
Topics: Adenosine Triphosphate; Biological Transport, Active; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Membrane Potentials; Oxygen Consumption; Rickettsia prowazekii | 1983 |
Toxic effects of ornithine and its related compounds on the retina.
Topics: Animals; Arginine; Citrulline; Glutamates; Glutamic Acid; Lysine; Ornithine; Pigment Epithelium of Eye; Proline; Putrescine; Rats; Rats, Inbred Strains; Retina | 1982 |
The function of vitamin A.
Topics: Animals; Arginine; Aspartic Acid; Bacteriorhodopsins; Biological Transport; Cell Differentiation; Cell Nucleus; Glutamates; Glutamic Acid; Halorhodopsins; Humans; Lysine; Ocular Physiological Phenomena; Rhodopsin; Tyrosine; Vitamin A | 1983 |
Relative deficiencies of amino acids and nitrogen per se in low protein diets for young turkeys.
Topics: Amino Acids; Animals; Body Weight; Dietary Proteins; Female; Glutamates; Glutamic Acid; Lysine; Male; Nitrogen; Threonine; Turkeys; Valine | 1983 |
Hemoglobin Kariya [alpha 40 (C5) Lys leads to Glu]: a new hemoglobin variant with an increased oxygen affinity.
Topics: Adult; Amino Acids; Genetic Variation; Glutamates; Glutamic Acid; Hemoglobins, Abnormal; Humans; Lysine; Male; Oxygen; Peptide Fragments | 1983 |
Influence of sequence and charge on the specificity of lysyl oxidase toward protein and synthetic peptide substrates.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Cattle; Glutamates; Glutamic Acid; Isoelectric Point; Kinetics; Lysine; Oligopeptides; Protein-Lysine 6-Oxidase; Structure-Activity Relationship; Substrate Specificity | 1984 |
Structure-activity studies with somatostatin: role of lysine in positions 4 and 9 for gastric activity.
Topics: Animals; Cats; Gastric Acid; Gastric Mucosa; Glutamates; Glutamic Acid; Lysine; Somatostatin; Structure-Activity Relationship; Threonine | 1984 |
Arginine uptake by isolated rat liver mitochondria.
Topics: Animals; Arginine; Citrulline; Glutamates; Glutamic Acid; Glutamine; Lysine; Male; Mitochondria, Heart; Mitochondria, Liver; Ornithine; Rats; Rats, Inbred Strains | 1984 |
Lysine residues at positions 234 and 236 in yeast porin are involved in its assembly into the mitochondrial outer membrane.
Topics: Amino Acid Sequence; Animals; Glutamic Acid; Humans; Intracellular Membranes; Lysine; Membrane Proteins; Mitochondria; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Plants; Point Mutation; Porins; Protein Structure, Secondary; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Voltage-Dependent Anion Channels | 1995 |
Estradiol-regulated transamidation of keratins by vaginal epithelial cell transglutaminase.
Topics: Amides; Animals; Calcium; Epithelium; Estradiol; Female; Gene Expression Regulation, Enzymologic; Glutamates; Glutamic Acid; Hydrolysis; Keratins; Lysine; Protein Conformation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Solubility; Transglutaminases; Vagina | 1994 |
Blood urea and amino acid concentrations in pigs of two breed combinations as affected by energy intakes.
Topics: Amino Acids; Animals; Aspartic Acid; Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Crosses, Genetic; Diet; Energy Intake; Energy Metabolism; Glutamic Acid; Histidine; Lysine; Male; Swine; Tyrosine; Weight Gain | 1995 |
Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants.
Topics: Biological Transport; Corynebacterium; Glutamic Acid; Homoserine Dehydrogenase; Isoleucine; Lysine; Methionine; Mutation | 1995 |
Alteration of the amino acid substrate specificity of clostridial glutamate dehydrogenase by site-directed mutagenesis of an active-site lysine residue.
Topics: Amino Acid Sequence; Amino Acids; Base Sequence; Binding Sites; Clostridium; Escherichia coli; Gene Expression; Glutamate Dehydrogenase; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Structure-Activity Relationship; Substrate Specificity | 1995 |
Arginine enhances glycogen synthesis in response to insulin in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adenosine Triphosphate; Adipocytes; Animals; Arginine; Biological Transport; Cell Line; Glucose; Glutamic Acid; Glycogen; Insulin; Lysine; Mice; Nitric Oxide; omega-N-Methylarginine | 1995 |
Convergent evolution of amino acid usage in archaebacterial and eubacterial lineages adapted to high salt.
Topics: Archaea; Arginine; Aspartic Acid; Bacterial Proteins; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Eubacterium; Glutamic Acid; In Vitro Techniques; Lysine; Oceans and Seas; Sodium Chloride | 1995 |
Uptake and metabolism of delta 1-piperidine-2-carboxylic acid by synaptosomes from rat cerebral cortex.
Topics: Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Lysine; Male; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Synaptosomes | 1995 |
Effects of different amino acids on the electrical characteristics of pharmaceutical polymers.
Topics: Alanine; Amino Acids; Chemistry, Pharmaceutical; Electrophoresis; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Lysine; Polymers; Threonine | 1995 |
A new missense mutation (E92K) in the first transmembrane domain of the CFTR gene causes a benign cystic fibrosis phenotype.
Topics: Base Sequence; Child; Codon; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Exons; Genotype; Glutamates; Glutamic Acid; Humans; Lysine; Male; Membrane Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Phenotype; Point Mutation; Polymerase Chain Reaction | 1993 |
Docking of nitrogenase iron- and molybdenum-iron proteins for electron transfer and MgATP hydrolysis: the role of arginine 140 and lysine 143 of the Azotobacter vinelandii iron protein.
Topics: Adenosine Triphosphate; Arginine; Azotobacter vinelandii; Chelating Agents; Electron Transport; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Models, Molecular; Molybdoferredoxin; Mutagenesis, Site-Directed; Nitrogenase; Oxidoreductases; Point Mutation; Protein Structure, Tertiary; Sodium Chloride | 1994 |
The effect of ion pairs on the thermal stability of D-glyceraldehyde 3-phosphate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Base Sequence; Enzyme Stability; Glutamic Acid; Glyceraldehyde-3-Phosphate Dehydrogenases; Gram-Negative Anaerobic Bacteria; Hot Temperature; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Sequence Alignment | 1994 |
Structural and functional consequences of a Glu L212-->Lys mutation in the QB binding site of the photosynthetic reaction center of Rhodopseudomonas viridis.
Topics: Atrazine; Electron Spin Resonance Spectroscopy; Electron Transport; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Photosynthetic Reaction Center Complex Proteins; Point Mutation; Protein Conformation; Rhodopseudomonas; Time Factors | 1994 |
Enhancement of synthesis and activity of yeast transport proteins by metabolic substrates.
Topics: Adenine; Biological Transport, Active; Carrier Proteins; Cycloheximide; Fungal Proteins; Glucose; Glutamic Acid; Kinetics; Lysine; Phosphates; Proton-Translocating ATPases; Saccharomyces cerevisiae; Sulfates; Uracil | 1994 |
Abnormal structure and co-operative binding of low-density lipoprotein receptors containing the Glu-80-->Lys mutation.
Topics: Animals; Binding Sites; Cell Line; Cells, Cultured; Glutamic Acid; Haplorhini; Humans; Hyperlipoproteinemia Type II; Lysine; Mutagenesis, Site-Directed; Mutation; Neuraminidase; Pronase; Receptors, LDL | 1995 |
Structure of the catalytic region of human complement protease C1s: study by chemical cross-linking and three-dimensional homology modeling.
Topics: Amino Acid Sequence; Binding Sites; Complement C1s; Computer Graphics; Cross-Linking Reagents; Cyanogen Bromide; Ethyldimethylaminopropyl Carbodiimide; Glutamic Acid; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Structure, Secondary; Sequence Homology, Amino Acid; Spectrometry, Mass, Fast Atom Bombardment; Thermolysin | 1995 |
Lemniscal and non-lemniscal synaptic transmission in rat auditory thalamus.
Topics: Animals; Auditory Pathways; Electric Stimulation; Excitatory Amino Acid Antagonists; Geniculate Bodies; Glutamic Acid; In Vitro Techniques; Inferior Colliculi; Lysine; Male; Microscopy, Electron; Microscopy, Fluorescence; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1994 |
Amino acid transport system y+L of human erythrocytes: specificity and cation dependence of the translocation step.
Topics: Amino Acids; Biological Transport; Carbon Radioisotopes; Erythrocyte Membrane; Erythrocytes; Ethylmaleimide; Glutamic Acid; Humans; Kinetics; Lysine; Mathematics; Models, Theoretical; Radioisotope Dilution Technique | 1994 |
Functional effects of mutations in the putative agonist binding region of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.
Topics: Animals; Base Sequence; Binding Sites; Female; Glutamic Acid; Glutamine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Receptors, AMPA; Recombinant Proteins; Xenopus | 1995 |
Identification of a substrate site for transglutaminases on the human protein synthesis initiation factor 5A.
Topics: Animals; Binding Sites; Caseins; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Eukaryotic Translation Initiation Factor 5A; Glutamic Acid; Guinea Pigs; Humans; Kinetics; Liver; Lysine; Peptide Initiation Factors; RNA-Binding Proteins; Transglutaminases | 1995 |
Autosomal dominant retinitis pigmentosa. A mutation in codon 181 (Glu-->Lys) of the rhodopsin gene in a Japanese family.
Topics: Adult; Base Sequence; Codon; DNA Mutational Analysis; Female; Fluorescein Angiography; Fundus Oculi; Glutamic Acid; Humans; Japan; Lysine; Molecular Sequence Data; Photoreceptor Cells; Point Mutation; Polymerase Chain Reaction; Retinitis Pigmentosa; Rhodopsin; Visual Fields | 1994 |
Dietary arginine deficiency and gut ammonium infusion alter flux of urea cycle intermediates across the portal-drained viscera of pigs.
Topics: Alanine; Animals; Arginine; Citrulline; Diet; Digestive System; Glutamic Acid; Glutamine; Lysine; Ornithine; Portal Vein; Quaternary Ammonium Compounds; Regional Blood Flow; Swine; Urea; Viscera | 1995 |
In the thermophilic archaeon Sulfolobus solfataricus a DNA-binding protein is in vitro (Adpribosyl)ated.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Amino Acids; Animals; Cattle; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; DNA-Binding Proteins; DNA, Bacterial; Glutamic Acid; Histones; Hot Temperature; Lysine; Molecular Sequence Data; Molecular Weight; NAD; Nucleic Acid Denaturation; Peptide Fragments; Sulfolobus | 1995 |
A periplasmic intermediate in the extracellular secretion pathway of Pseudomonas aeruginosa exotoxin A.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Bacterial Toxins; Base Sequence; Cell Membrane; DNA Primers; Exotoxins; Genes, Bacterial; Glutamates; Glutamic Acid; Glutamine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Virulence Factors | 1993 |
Protein and DNA sequence analysis of a 'private' genetic variant: albumin Ortonovo (Glu-505-->Lys).
Topics: Amino Acid Sequence; Base Sequence; Female; Glutamates; Glutamic Acid; Heterozygote; Humans; Italy; Lysine; Molecular Sequence Data; Polymorphism, Genetic; Serum Albumin; Serum Albumin, Human | 1993 |
Mutations in two specific residues of testicular angiotensin-converting enzyme change its catalytic properties.
Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitive; Gene Expression; Genetic Vectors; Glutamates; Glutamic Acid; HeLa Cells; Humans; Kinetics; Lisinopril; Lysine; Male; Mutagenesis; Peptidyl-Dipeptidase A; Phenylalanine; Point Mutation; Rabbits; Recombinant Proteins; Substrate Specificity; Testis; Transfection; Tyrosine; Vaccinia virus | 1993 |
Plurality of protein conformations of ribulose-1,5-bisphosphate carboxylase/oxygenase monomers probed by high pressure electrophoresis.
Topics: Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Hydrostatic Pressure; Kinetics; Lysine; Macromolecular Substances; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Recombinant Proteins; Ribulose-Bisphosphate Carboxylase; Spectrometry, Fluorescence; Thermodynamics | 1993 |
Mutagenesis of the conserved lysine 14 of cytochrome c-550 from Thiobacillus versutus affects the protein structure and the electron self-exchange rate.
Topics: Conserved Sequence; Cytochrome c Group; Electrons; Glutamates; Glutamic Acid; Glutamine; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Thiobacillus | 1993 |
Abnormal messenger RNA expression and a missense mutation in patients with X-linked adrenoleukodystrophy.
Topics: Adrenoleukodystrophy; Amino Acid Sequence; ATP-Binding Cassette Transporters; Base Sequence; Blotting, Northern; Cloning, Molecular; Conserved Sequence; DNA Probes; Exons; Female; Fibroblasts; Glutamates; Glutamic Acid; Humans; Lysine; Male; Membrane Proteins; Microbodies; Molecular Sequence Data; Pedigree; Point Mutation; RNA, Messenger; Sequence Deletion; Transcription, Genetic; X Chromosome | 1993 |
Identification of Hb Anantharaj [alpha 11(A9)Lys->Glu] as Hb J-Wenchang-Wuming [alpha 11(A9)Lys->Gln].
Topics: Adult; Glutamates; Glutamic Acid; Glutamine; Hemoglobins, Abnormal; Humans; Lysine; Male; Middle Aged | 1993 |
Quantitation of epsilon-amino group using amino acids as reference standards by trinitrobenzene sulfonic acid. A simple spectrophotometric method for the estimation of hapten to carrier protein ratio.
Topics: Antigens; Glutamates; Glutamic Acid; Haptens; Lysine; Reference Standards; Spectrophotometry; Trinitrobenzenes; Trinitrobenzenesulfonic Acid | 1994 |
Role of the divalent metal ion in sugar binding, ring opening, and isomerization by D-xylose isomerase: replacement of a catalytic metal by an amino acid.
Topics: Aldose-Ketose Isomerases; Amino Acids; Base Sequence; Binding Sites; Carbohydrate Epimerases; Carbohydrate Metabolism; Catalysis; Cations, Divalent; Crystallography, X-Ray; Glutamates; Glutamic Acid; Lysine; Magnesium; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Streptomyces; Structure-Activity Relationship | 1994 |
Activity of the E75E76 mutant of the alpha subunit of casein kinase II from Xenopus laevis.
Topics: Amino Acid Sequence; Animals; Base Sequence; Casein Kinase II; DNA, Complementary; Electrochemistry; Glutamates; Glutamic Acid; Lysine; Molecular Sequence Data; Mutation; Poly U; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Quercetin; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis | 1994 |
Mutation of Glu-80-->Lys results in a protein C mutant that no longer requires Ca2+ for rapid activation by the thrombin-thrombomodulin complex.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Calcium; DNA Primers; Enzyme Activation; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Rabbits; Sequence Homology, Amino Acid; Thrombin; Thrombomodulin; Trypsin | 1994 |
Kinetics of the reduction of cytochrome b5 with mutations in its membrane-binding domain.
Topics: Alanine; Amino Acid Sequence; Animals; Cloning, Molecular; Cytochrome P-450 Enzyme System; Cytochromes b5; Genes, Synthetic; Glutamates; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Point Mutation; Proline; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry | 1994 |
Missense mutations in the arylsulphatase A genes of metachromatic leukodystrophy patients.
Topics: Adult; Amino Acid Sequence; Base Sequence; Cerebroside-Sulfatase; Child; DNA Primers; Exons; Glutamates; Glutamic Acid; Homozygote; Humans; Infant; Leukodystrophy, Metachromatic; Lysine; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic | 1993 |
Contribution of a proline residue and a salt bridge to the stability of a type I reverse turn in chymotrypsin inhibitor-2.
Topics: Amino Acid Sequence; Base Sequence; Calorimetry, Differential Scanning; Circular Dichroism; Glutamates; Glutamic Acid; Hydrogen Bonding; Lysine; Molecular Sequence Data; Peptides; Plant Proteins; Proline; Protein Denaturation; Protein Structure, Tertiary | 1994 |
Fast-type electrophoretic variant of lactate dehydrogenase M(A) and comparison with other missense mutations in lactate dehydrogenase M(A) and H(B) genes.
Topics: Base Sequence; Chest Pain; Codon; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis; Female; Glutamates; Glutamic Acid; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lysine; Middle Aged; Molecular Sequence Data; Mutation; Polymerase Chain Reaction | 1994 |
The first developing "mixed" synapses between vestibular sensory neurons mediate glutamate chemical transmission.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Intercellular Junctions; Lysine; Neurons, Afferent; Quinoxalines; Reflex, Vestibulo-Ocular; Synapses; Synaptic Transmission; Vestibular Nerve | 1994 |
Possible gene dose effect of a mutant cardiac beta-myosin heavy chain gene on the clinical expression of familial hypertrophic cardiomyopathy.
Topics: Adenine; Adult; Amino Acid Sequence; Animals; Base Sequence; Cardiomyopathy, Hypertrophic; Chickens; Codon; DNA Primers; Echocardiography; Female; Glutamates; Glutamic Acid; Guanine; Humans; Lysine; Male; Molecular Sequence Data; Myocardium; Myosins; Pedigree; Point Mutation; Polymerase Chain Reaction; Rats; Sequence Homology, Amino Acid | 1994 |
Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Amino Acid Sequence; Animals; Asian People; Base Sequence; Binding Sites; Catalysis; DNA Primers; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mitochondria, Liver; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligodeoxyribonucleotides; Rats; Recombinant Proteins; Sequence Homology, Amino Acid | 1994 |
Site-directed mutagenesis of glutamate-166 in beta-lactamase leads to a branched path mechanism.
Topics: Acylation; Bacillus; Base Sequence; beta-Lactamases; Catalysis; Circular Dichroism; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Structure-Activity Relationship; Sulfates | 1994 |
Three new mutations of thyroid hormone receptor-beta associated with resistance to thyroid hormone.
Topics: Adolescent; Adult; Amino Acid Sequence; Asparagine; Aspartic Acid; Base Sequence; Drug Resistance; Female; Glutamates; Glutamic Acid; Glutamine; Humans; Lysine; Male; Molecular Sequence Data; Point Mutation; Receptors, Thyroid Hormone; Sicily; Syndrome; Thyroid Hormones | 1994 |
The human platelet alloantigens, HPA-5(a+, b-) and HPA-5(a-, b+), are associated with a Glu505/Lys505 polymorphism of glycoprotein Ia (the alpha 2 subunit of VLA-2).
Topics: Antigens, Human Platelet; Base Sequence; Blood Platelets; Glutamates; Glutamic Acid; Humans; Integrin beta3; Lysine; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Platelet Membrane Glycoproteins; Polymerase Chain Reaction; Polymorphism, Genetic | 1994 |
Replacement of all alpha-domain lysines with glutamates reduces metallothionein detoxification function.
Topics: Binding Sites; Cadmium; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Gene Transfer Techniques; Glutamates; Glutamic Acid; Lysine; Metallothionein; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Structure-Activity Relationship | 1994 |
Glucose potentiation of arginine-induced insulin secretion is impaired in subjects with a glucokinase Glu256Lys mutation.
Topics: Adult; Arginine; Blood Glucose; Drug Synergism; Female; Glucagon; Glucokinase; Glucose; Glucose Tolerance Test; Glutamic Acid; Humans; Insulin; Insulin Secretion; Lysine; Male; Middle Aged; Mutation | 1994 |
The cooperative binding of chromosomal protein HMG-14 to nucleosome cores is reduced by single point mutations in the nucleosomal binding domain.
Topics: Alanine; Base Sequence; Binding Sites; Cysteine; Escherichia coli; Gene Expression; Glutamic Acid; High Mobility Group Proteins; Humans; Iodoacetamide; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleosomes; Point Mutation; Protein Conformation; Recombinant Proteins; Structure-Activity Relationship; Sulfhydryl Compounds | 1994 |
Characterization of a disease-causing Glu119-Lys mutation in the low-density lipoprotein receptor gene in two Danish families with heterozygous familial hypercholesterolemia.
Topics: Adult; Base Sequence; Female; Glutamic Acid; Humans; Hyperlipoproteinemia Type II; Lysine; Male; Middle Aged; Molecular Sequence Data; Mutagenesis, Site-Directed; Pedigree; Point Mutation; Polymerase Chain Reaction; Receptors, LDL | 1994 |
Residue lysine-34 in GroES modulates allosteric transitions in GroEL.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Allosteric Site; Base Sequence; Chaperonin 10; Chaperonin 60; Glutamic Acid; Hydrolysis; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Potassium Chloride; Structure-Activity Relationship; Thermodynamics | 1994 |
The real-time resolution of proton-related transient-state steps in an enzymatic reaction. The early steps in the oxidative deamination reaction of bovine liver glutamate dehydrogenase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Clostridium; Deamination; Enzymes; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Liver; Lysine; Macromolecular Substances; Mathematics; Models, Molecular; Models, Theoretical; Oxidation-Reduction; Protein Conformation; Time Factors | 1993 |
The identification of elements determining the different DNA binding specificities of the MADS box proteins p67SRF and RSRFC4.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; DNA; DNA-Binding Proteins; Glutamates; Glutamic Acid; Humans; Lysine; MADS Domain Proteins; MEF2 Transcription Factors; Molecular Sequence Data; Myogenic Regulatory Factors; Nuclear Proteins; Sequence Homology, Amino Acid; Serum Response Factor; Transcription Factors | 1993 |
Substitution of Glu841 by lysine in the carbamate domain of carbamyl phosphate synthetase alters the catalytic properties of the glutaminase subunit.
Topics: Amino Acid Sequence; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Escherichia coli; Genes, Bacterial; Glutamates; Glutamic Acid; Glutaminase; Hydrogen-Ion Concentration; Kinetics; Lysine; Macromolecular Substances; Mathematics; Recombinant Proteins | 1993 |
Characterization of a lysine-to-glutamic acid mutation in a conservative sequence of farnesyl diphosphate synthase from Saccharomyces cerevisiae.
Topics: Acyclic Monoterpenes; Alkyl and Aryl Transferases; Alleles; Amino Acid Sequence; Animals; Base Sequence; Conserved Sequence; DNA, Fungal; Geranyltranstransferase; Glutamates; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Mutation; Restriction Mapping; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Terpenes; Transferases | 1993 |
Site-directed mutagenesis of alpha-tubulin. Reductive methylation studies of the Lys 394 region.
Topics: Animals; Biophysical Phenomena; Biophysics; Cattle; Glutamates; Glutamic Acid; In Vitro Techniques; Lysine; Methylation; Microtubule Proteins; Mutagenesis, Site-Directed; Oxidation-Reduction; Tubulin | 1993 |
Crystal structure analysis of a mutant Escherichia coli thioredoxin in which lysine 36 is replaced by glutamic acid.
Topics: Binding Sites; Copper; Crystallization; Disulfides; Drug Stability; Escherichia coli; Glutamates; Glutamic Acid; Hydrogen Bonding; Lysine; Molecular Structure; Mutagenesis; Protein Conformation; Solvents; Spectrometry, Fluorescence; Thioredoxins; X-Ray Diffraction | 1993 |
Effect of different positively charged amino acids, C-terminally of the signal peptidase cleavage site, on the translocation kinetics of a precursor protein in Escherichia coli K-12.
Topics: Amino Acids; Arginine; Bacterial Outer Membrane Proteins; Bacterial Proteins; Base Sequence; Biological Transport; DNA, Bacterial; Electrochemistry; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Glutamates; Glutamic Acid; Histidine; Kinetics; Lysine; Membrane Proteins; Molecular Sequence Data; Porins; Protein Precursors; Serine Endopeptidases | 1993 |
Baboon apolipoprotein A-IV. Identification of Lys76-->Glu that distinguishes two common isoforms and detection of length polymorphisms at the carboxyl terminus.
Topics: Amino Acid Sequence; Animals; Apolipoproteins A; Base Sequence; DNA; Genetic Variation; Glutamates; Glutamic Acid; Humans; Isoelectric Focusing; Lysine; Molecular Sequence Data; Papio; Polymerase Chain Reaction; Sequence Alignment | 1993 |
Mechanism of the enhanced intrinsic activity of single-chain urokinase-type plasminogen activator during ongoing fibrinolysis.
Topics: Alanine; Binding Sites; Catalysis; Cell Line; Enzyme Activation; Fibrin; Fibrinolysis; Glutamates; Glutamic Acid; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Plasminogen; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Serine; Solutions; Urokinase-Type Plasminogen Activator | 1993 |
Lysine 319 interacts with both glutamic acid 269 and aspartic acid 240 in the lactose carrier of Escherichia coli.
Topics: Amino Acid Sequence; Aspartic Acid; Base Sequence; Cell Membrane; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Genotype; Glutamates; Glutamic Acid; Kinetics; Lactose; Lysine; Melibiose; Membrane Transport Proteins; Models, Structural; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Structure, Secondary; Recombinant Proteins; Symporters | 1993 |
Co-overexpression of bacterial GroESL chaperonins partly overcomes non-productive folding and tetramer assembly of E. coli-expressed human medium-chain acyl-CoA dehydrogenase (MCAD) carrying the prevalent disease-causing K304E mutation.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Bacterial Proteins; Base Sequence; Chaperonins; Escherichia coli; Gene Expression; Glutamates; Glutamic Acid; Glutamine; Humans; Lysine; Molecular Sequence Data; Mutation; Plasmids; Protein Folding; Proteins | 1993 |
A survey of a functional amino acid of class C beta-lactamase corresponding to Glu166 of class A beta-lactamases.
Topics: Alanine; Amino Acid Sequence; Base Sequence; beta-Lactamases; DNA Primers; Escherichia coli; Glutamates; Glutamic Acid; Glutamine; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Homology, Amino Acid | 1993 |
Identification of two amino acid residues on the extracellular domain of the lutropin/choriogonadotropin receptor important in signaling.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Cell Line; Chlorocebus aethiops; Chorionic Gonadotropin; Cyclic AMP; DNA, Complementary; Glutamic Acid; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Point Mutation; Rats; Receptors, LH; Recombinant Proteins; Signal Transduction; Transfection | 1995 |
Conformational changes in oxyhemoglobin C (Glu beta 6-->Lys) detected by spectroscopic probing.
Topics: Glutamic Acid; Humans; Lysine; Oxyhemoglobins; Protein Conformation; Spectrum Analysis | 1996 |
Substitution of a single amino acid residue is sufficient to allow the human amphotropic murine leukemia virus receptor to also function as a gibbon ape leukemia virus receptor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Cricetulus; Glutamic Acid; Humans; Leukemia Virus, Feline; Leukemia Virus, Gibbon Ape; Leukemia Virus, Murine; Lysine; Molecular Sequence Data; Receptors, Virus; Structure-Activity Relationship | 1996 |
A difference in the sequence of steps in the reactions catalyzed by two closely homologous forms of glutamate dehydrogenase.
Topics: Animals; Aspartic Acid; Binding Sites; Cattle; Clostridium; Glutamate Dehydrogenase; Glutamic Acid; Kinetics; Liver; Lysine; Protein Binding; Serine; Time Factors | 1996 |
Ion pairs significantly stabilize coiled-coils in the absence of electrolyte.
Topics: Amino Acid Sequence; Chlorides; Circular Dichroism; Electrolytes; Glutamic Acid; Hot Temperature; Hydrogen-Ion Concentration; Ions; Lysine; Molecular Sequence Data; Osmolar Concentration; Peptides; Protein Denaturation; Protein Structure, Secondary; Sodium | 1996 |
Catalytic properties and structural components of lysyl oxidase.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Blotting, Western; Catalysis; Cattle; CHO Cells; Collagen; Cricetinae; Elastin; Gene Expression Regulation, Enzymologic; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Oxidation-Reduction; Protein Processing, Post-Translational; Protein-Lysine 6-Oxidase; Recombinant Proteins; RNA, Messenger; Substrate Specificity | 1995 |
[Methodical investigations on evaluation of lysine utilization in pigs after extreme changes of protein quantity and quality].
Topics: Animal Feed; Animals; Dietary Proteins; Female; Food, Fortified; Glutamic Acid; Glutens; Lysine; Models, Biological; Nitrogen; Starch; Swine; Triticum | 1995 |
Interhelical salt bridges, coiled-coil stability, and specificity of dimerization.
Topics: DNA-Binding Proteins; Fungal Proteins; Glutamic Acid; Glutamine; Leucine Zippers; Lysine; Protein Conformation; Protein Folding; Protein Kinases; Protein Structure, Secondary; Saccharomyces cerevisiae Proteins; Thermodynamics | 1996 |
Interaction of substrate uridyl 3',5'-adenosine with ribonuclease A: a molecular dynamics study.
Topics: Animals; Binding Sites; Cattle; Dinucleoside Phosphates; Glutamic Acid; Glutamine; Histidine; Kinetics; Lysine; Models, Molecular; Molecular Conformation; Protein Conformation; Ribonuclease, Pancreatic | 1995 |
Design of heterotetrameric coiled coils: evidence for increased stabilization by Glu(-)-Lys(+) ion pair interactions.
Topics: Amino Acid Sequence; Calorimetry; Computer Graphics; Electrochemistry; Glutamic Acid; Hot Temperature; Kinetics; Lysine; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Oncogene Protein p65(gag-jun); Oncogene Proteins v-fos; Peptides; Protein Denaturation; Protein Structure, Secondary; Structure-Activity Relationship; Thermodynamics | 1996 |
A single point mutation in epsilon-COP results in temperature-sensitive, lethal defects in membrane transport in a Chinese hamster ovary cell mutant.
Topics: Amino Acid Sequence; Animals; Antibodies; Biological Transport; Cell Membrane; CHO Cells; Coatomer Protein; Cricetinae; Genes, Lethal; Glutamic Acid; Kinetics; Lysine; Membrane Proteins; Molecular Sequence Data; Peptide Fragments; Point Mutation; Recombinant Proteins; Temperature; Transfection | 1996 |
E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylation.
Topics: 3T3 Cells; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Viral; Glutamic Acid; Golgi Apparatus; Hematopoietic Stem Cells; Lysine; Mice; Molecular Sequence Data; Oncogene Proteins, Viral; Phosphorylation; Point Mutation; Protein Binding; Receptors, Platelet-Derived Growth Factor; Serine | 1996 |
Calcification of pericardial tissue pretreated with different amino acids.
Topics: Amino Acids; Analysis of Variance; Animals; Arginine; Bioprosthesis; Calcinosis; Calcium; Cardiomyopathies; Cattle; Female; Glutamic Acid; Glutamine; Glutaral; Heart Valve Prosthesis; Lysine; Pericardium; Rats; Rats, Wistar; Spectrophotometry, Atomic; Structure-Activity Relationship | 1996 |
Lipoylation of acyltransferase components of alpha-ketoacid dehydrogenase complexes.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acyltransferases; Animals; Base Sequence; Cattle; Cloning, Molecular; Conserved Sequence; DNA, Complementary; Glutamic Acid; Glycine; Ketone Oxidoreductases; Lysine; Mitochondria, Liver; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Thioctic Acid | 1996 |
ATP and SH3 binding sites in the protein kinase of the large subunit of herpes simplex virus type 2 of ribonucleotide reductase (ICP10).
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Chlorocebus aethiops; ErbB Receptors; Glutamic Acid; GRB2 Adaptor Protein; Humans; Kidney; Lysine; Magnesium; Manganese; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Proteins; Recombinant Proteins; Ribonucleotide Reductases; Simplexvirus; src Homology Domains; Vero Cells | 1996 |
Structure and critical residues at the active site of spermidine/spermine-N1-acetyltransferase.
Topics: Acetyl Coenzyme A; Acetyltransferases; Alanine; Amino Acid Sequence; Animals; Arginine; Binding Sites; Chlorocebus aethiops; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Protein Biosynthesis; Recombinant Proteins; Transfection | 1996 |
The role of specific lysine residues in the passage of anions through the Pseudomonas aeruginosa porin OprP.
Topics: Anions; Bacterial Proteins; Glutamic Acid; Ion Transport; Lysine; Mutagenesis, Site-Directed; Phosphates; Porins; Pseudomonas aeruginosa | 1996 |
The role of acidic amino acid residues in the structural stability of snake cardiotoxins.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Circular Dichroism; Cobra Cardiotoxin Proteins; Disulfides; Glutamic Acid; Guanidine; Guanidines; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Trifluoroethanol | 1996 |
Charge-affected transperitoneal movement of amino acids in CAPD.
Topics: Adult; Aged; Ascitic Fluid; Capillary Permeability; Creatinine; Dialysis Solutions; Female; Glutamic Acid; Glutamine; Humans; Kidney Failure, Chronic; Lysine; Male; Membrane Potentials; Middle Aged; Peritoneum | 1996 |
Active site properties of monomeric triosephosphate isomerase (monoTIM) as deduced from mutational and structural studies.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Catalysis; Chickens; Circular Dichroism; Enzyme Inhibitors; Fungal Proteins; Glutamic Acid; Glycolates; Histidine; Hydroxamic Acids; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protozoan Proteins; Saccharomyces cerevisiae; Species Specificity; Structure-Activity Relationship; Substrate Specificity; Triose-Phosphate Isomerase; Trypanosoma | 1996 |
Dietary wheat gluten alleviates the elevation of serum transaminase activities in D-galactosamine-injected rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dietary Proteins; Galactosamine; Glutamic Acid; Glutens; Kinetics; Lysine; Male; Rats; Rats, Wistar; Threonine; Triticum; Uracil Nucleotides | 1996 |
Time-dependent current decline in cyclic GMP-gated bovine channels caused by point mutations in the pore region expressed in Xenopus oocytes.
Topics: Amino Acid Sequence; Animals; Cattle; Cyclic GMP; Dimethylamines; Electrophysiology; Glutamic Acid; Ion Channel Gating; Lysine; Molecular Sequence Data; Mutagenesis; Oocytes; Point Mutation; Time Factors; Xenopus laevis | 1996 |
Effect of amino acids on the stability properties of nitrofurantoin suspensions. Flocculation and redispersion compared with interaction energy curves.
Topics: Alanine; Amino Acids; Drug Stability; Electrochemistry; Flocculation; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Nitrofurantoin; Particle Size; Solubility; Suspensions | 1996 |
Mutagenesis analysis of functionally important domains within the C-terminal end of smooth muscle caldesmon.
Topics: Actins; Amino Acid Sequence; Animals; Baculoviridae; Calmodulin-Binding Proteins; Cell Line; Chickens; DNA Primers; Gizzard, Avian; Glutamic Acid; Kinetics; Lysine; Muscle, Smooth; Mutagenesis, Site-Directed; Myosins; Point Mutation; Recombinant Proteins; Sequence Deletion; Transfection | 1996 |
Verification of Hb O-Arab [beta 121(GH4)Glu-->Lys] by dual restriction enzyme analysis.
Topics: Globins; Glutamic Acid; Hemoglobins, Abnormal; Heterozygote; Humans; Lysine; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 1996 |
Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Chromatography, Ion Exchange; Cloning, Molecular; Conserved Sequence; Cysteine; DNA Helicases; DNA Probes; Escherichia coli; Fungal Proteins; Glutamic Acid; Histidine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; RNA Helicases; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators | 1996 |
The apoB-100 gene EcoRI polymorphism influences the relationship between features of the insulin resistance syndrome and the hyper-apoB and dense LDL phenotype in men.
Topics: Adipose Tissue; Adult; Apolipoprotein B-100; Apolipoproteins B; Blood Glucose; Body Mass Index; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Codon; Deoxyribonuclease EcoRI; Fatty Acids, Nonesterified; Genotype; Glucose Tolerance Test; Glutamic Acid; Heterozygote; Humans; Insulin Resistance; Lipoproteins, LDL; Lysine; Male; Phenotype; Polymorphism, Restriction Fragment Length; Triglycerides | 1996 |
Rate of pellicle formation in vivo.
Topics: Adsorption; Adult; Alanine; Amino Acids; Dental Deposits; Dental Enamel; Dental Pellicle; Glutamic Acid; Glycine; Humans; Lysine; Middle Aged; Proline; Salivary Proteins and Peptides; Spectrum Analysis; Time Factors | 1995 |
Two amino acid differences in the sixth transmembrane domain are partially responsible for the pharmacological differences between the 5-HT1D beta and 5-HT1E 5-hydroxytryptamine receptors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Cloning, Molecular; COS Cells; DNA Primers; Ergolines; Glutamic Acid; Humans; Isoleucine; Kinetics; Ligands; Lysine; Models, Structural; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Serotonin; Transfection | 1996 |
Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint.
Topics: Animals; COS Cells; Cricetinae; Epinephrine; Glutamic Acid; Inositol Phosphates; Lysine; Methoxamine; Mutagenesis, Site-Directed; Norepinephrine; Protein Conformation; Receptors, Adrenergic, alpha-1; Signal Transduction; Structure-Activity Relationship | 1996 |
Improved thermostability of the North American firefly luciferase: saturation mutagenesis at position 354.
Topics: Animals; Coleoptera; Glutamic Acid; Luciferases; Lysine; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Temperature | 1996 |
Glu227-->Lys substitution in the acidic loop of major histocompatibility complex class I alpha 3 domain distinguishes low avidity CD8 coreceptor and avidity-enhanced CD8 accessory functions.
Topics: Binding Sites; CD8 Antigens; Cell Adhesion; Cell Degranulation; Clone Cells; Cytotoxicity, Immunologic; Glutamic Acid; H-2 Antigens; Histocompatibility Antigens Class I; Ligands; Lymphocyte Activation; Lysine; Mutation; Peptide Fragments; Protein Conformation; Receptors, Antigen, T-Cell; Recombinant Fusion Proteins; Signal Transduction; T-Lymphocytes, Cytotoxic; Viral Core Proteins | 1996 |
Replacement of Lys by Glu in a transmembrane segment strongly impairs the function of the uracil permease from Saccharomyces cerevisiae.
Topics: Blotting, Western; Carrier Proteins; Cell Membrane; Glutamic Acid; Kinetics; Lysine; Membrane Proteins; Membrane Transport Proteins; Models, Molecular; Mutation; Nucleotide Transport Proteins; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transformation, Genetic; Uracil | 1995 |
The glutamic acid residue at amino acid 261 of the alpha subunit is a determinant of the intrinsic efficiency of RNA polymerase at the metE core promoter in Escherichia coli.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Alanine; Bacterial Proteins; Base Sequence; Codon; DNA-Directed RNA Polymerases; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Lysine; Methyltransferases; Molecular Sequence Data; Promoter Regions, Genetic; Recombinant Fusion Proteins; Sequence Deletion; Suppression, Genetic; Trans-Activators; Transcription, Genetic | 1996 |
Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2).
Topics: Alleles; Amino Acid Sequence; Anthraquinones; Anti-Bacterial Agents; Base Sequence; DNA, Bacterial; Drug Resistance, Microbial; Glutamic Acid; Lysine; Molecular Sequence Data; Point Mutation; Ribosomal Proteins; Sequence Homology, Amino Acid; Streptomyces; Streptomycin | 1996 |
[Charge selectivity of peritoneal transport in CAPD patients under stable states and during peritonitis].
Topics: Adult; Aged; Amino Acids; Biological Transport; Female; Glutamic Acid; Glutamine; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Peritonitis | 1996 |
Site-directed mutagenesis of the amino acid residues in beta-strand III [Val30-Val36] of D-amino acid aminotransferase of Bacillus sp. YM-1.
Topics: Alanine Transaminase; Bacillus; Binding Sites; D-Alanine Transaminase; Glutamic Acid; Hemiterpenes; Hydrogen Bonding; Hydrogen-Ion Concentration; Keto Acids; Ketoglutaric Acids; Kinetics; Lysine; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Spectrometry, Fluorescence; Valine | 1996 |
Electrostatic interaction between two domains of isocitrate dehydrogenase from Thermus thermophilus is important for the catalytic function and protein stability.
Topics: Amino Acid Sequence; Catalysis; Electrochemistry; Enzyme Stability; Glutamic Acid; Glutamine; Hot Temperature; Isocitrate Dehydrogenase; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Thermus thermophilus | 1996 |
Charged amino acids near the pore entrance influence ion-conduction of a human L-type cardiac calcium channel.
Topics: Amino Acid Sequence; Amino Acids; Animals; Aspartic Acid; Calcium; Calcium Channels; Electric Conductivity; Glutamic Acid; Heart; Humans; Lysine; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid; Xenopus | 1997 |
Biosynthesis of 'essential' amino acids by scleractinian corals.
Topics: Amino Acids, Essential; Animals; Carbon Radioisotopes; Cnidaria; Glucose; Glutamic Acid; Lysine; Valine | 1997 |
Hydrolysis of gamma:epsilon isopeptides by cytosolic transglutaminases and by coagulation factor XIIIa.
Topics: Animals; Calcium; Cytosol; Glutamic Acid; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lysine; Peptides; Spectrometry, Fluorescence; Structure-Activity Relationship; Transglutaminases | 1997 |
Solvent structure at a hydrophobic protein surface.
Topics: Amino Acid Sequence; Binding Sites; Chloroform; Computer Simulation; Connectin; Glutamic Acid; Lysine; Methanol; Models, Chemical; Molecular Sequence Data; Muscle Proteins; Peptide Fragments; Protein Kinases; Proteolipids; Pulmonary Surfactants; Solvents; Surface Properties; Water | 1997 |
Increased thermo-stability of rat prolactin after replacing glutamic acid at position 118 by lysine.
Topics: Animals; Cell Division; Glutamic Acid; Hot Temperature; Lymphoma; Lysine; Mutagenesis, Site-Directed; Prolactin; Rats; Tumor Cells, Cultured | 1996 |
pKa measurements from nuclear magnetic resonance for the B1 and B2 immunoglobulin G-binding domains of protein G: comparison with calculated values for nuclear magnetic resonance and X-ray structures.
Topics: Aspartic Acid; Binding Sites; Crystallography, X-Ray; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Immunoglobulin G; Lysine; Magnetic Resonance Spectroscopy; Nerve Tissue Proteins; Protein Conformation; Protein Kinases; Substrate Specificity; Tyrosine | 1997 |
A topological model for the general aromatic amino acid permease, AroP, of Escherichia coli.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Amino Acid Transport Systems; Bacterial Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Enzyme Activation; Enzyme Stability; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Lysine; Membrane Transport Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed | 1997 |
Kinetic analysis of a mutational hot spot in the EcoRV restriction endonuclease.
Topics: Binding Sites; Calcium; Cations, Divalent; Deoxyribonucleases, Type II Site-Specific; DNA; Glutamic Acid; Glutamine; Kinetics; Leucine; Lysine; Magnesium; Mutagenesis; Protein Conformation; Structure-Activity Relationship | 1997 |
Biochemical characterization of purified, human recombinant Lys304-->Glu medium-chain acyl-CoA dehydrogenase containing the common disease-causing mutation and comparison with the normal enzyme.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenase, Long-Chain; Catalysis; Glutamic Acid; Humans; Kinetics; Lysine; Mutation; Oxidation-Reduction; Recombinant Proteins; Substrate Specificity | 1997 |
A single mutation in the M-subunit of Rhodospirillum rubrum confers herbicide resistance.
Topics: Drug Resistance, Microbial; Electron Spin Resonance Spectroscopy; Glutamic Acid; Herbicides; Lysine; Mutation; Photosynthetic Reaction Center Complex Proteins; Rhodospirillum rubrum; Thiazoles | 1997 |
Involvement of glutamate 399 and lysine 192 in the mechanism of human liver mitochondrial aldehyde dehydrogenase.
Topics: Acetaldehyde; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Glutamic Acid; Humans; Isoelectric Point; Kinetics; Lysine; Magnesium; Mitochondria, Liver; Mutagenesis, Site-Directed; Structure-Activity Relationship | 1997 |
A cucumber necrosis virus variant deficient in fungal transmissibility contains an altered coat protein shell domain.
Topics: Binding Sites; Capsid; Chytridiomycota; Cucumis sativus; Defective Viruses; Glutamic Acid; Lysine; Mutation; Point Mutation; Tombusvirus | 1997 |
Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix.
Topics: Adolescent; Child; Female; Glutamic Acid; Hair Diseases; Heterozygote; Humans; Keratins; Lysine; Male; Middle Aged; Mutation; Pedigree | 1997 |
Efflux of compatible solutes in Corynebacterium glutamicum mediated by osmoregulated channel activity.
Topics: Adenosine Triphosphate; Alanine; Amino Acids; Amino Acids, Diamino; Betaine; Corynebacterium; Glutamic Acid; Glycine; Homeostasis; Hypotonic Solutions; Ion Channels; Kinetics; Lysine; Membrane Potentials; Osmolar Concentration; Potassium; Proline; Sodium | 1997 |
A homeo-interaction sequence in the ectodomain of the fibroblast growth factor receptor.
Topics: Amino Acid Sequence; Animals; Cell Line; Fibroblast Growth Factors; Glutamic Acid; Heparin; Heparitin Sulfate; Lysine; Mitogens; Molecular Sequence Data; Protein Binding; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Sequence Homology, Amino Acid; Spodoptera | 1997 |
Specificity of ligand-induced conformational change of lipoprotein(a).
Topics: Aminocaproic Acid; Glutamic Acid; Ligands; Lipoprotein(a); Lysine; Models, Chemical; Molecular Weight; Osmolar Concentration; Particle Size; Proline; Protein Conformation; Protein Denaturation; Salts; Tranexamic Acid; Ultracentrifugation | 1997 |
Functional dynamics of GABAergic inhibition in the thalamus.
Topics: Action Potentials; Animals; Bicuculline; Dendrites; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; In Vitro Techniques; Lysine; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Thalamic Nuclei | 1997 |
Factors which stabilize the methylamine dehydrogenase-amicyanin electron transfer protein complex revealed by site-directed mutagenesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Bacterial Proteins; Cloning, Molecular; Copper; Escherichia coli; Glutamic Acid; Indolequinones; Lysine; Metalloproteins; Models, Molecular; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Phenylalanine; Protein Conformation; Quinones; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Tryptophan | 1997 |
Detection of a genetic variant, lysine-->glutamic acid at position 372 of human serum albumin, by capillary electrophoresis and structural identification.
Topics: Amino Acid Sequence; Amino Acid Substitution; Electrophoresis, Capillary; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Peptide Mapping; Serum Albumin | 1997 |
Heparin binding of protein-C inhibitor--analysis of the effect of heparin on the interaction of protein-C inhibitor with tissue kallikrein.
Topics: Aprotinin; Autoradiography; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Glycine; Heparin; Iodine Radioisotopes; Kallikreins; Lysine; Protein C Inhibitor; Tissue Kallikreins; Urokinase-Type Plasminogen Activator | 1997 |
Destabilization of peptide binding and interdomain communication by an E543K mutation in the bovine 70-kDa heat shock cognate protein, a molecular chaperone.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Brain; Carrier Proteins; Cations, Monovalent; Cattle; Cloning, Molecular; Escherichia coli; Glutamic Acid; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Protein Binding; Recombinant Proteins; Scattering, Radiation; X-Rays | 1997 |
Constrained corticotropin-releasing factor antagonists with i-(i + 3) Glu-Lys bridges.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Corticotropin-Releasing Hormone; Glutamic Acid; Humans; Lysine; Male; Molecular Sequence Data; Pituitary Gland, Anterior; Protein Conformation; Rats; Rats, Sprague-Dawley; Sequence Homology, Amino Acid; Spectrum Analysis | 1997 |
5-HT inhibits lateral entorhinal cortical neurons of the rat in vitro by activation of potassium channel-coupled 5-HT1A receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthetics, Local; Animals; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Lidocaine; Lysine; Male; Neural Inhibition; Neurons; Perforant Pathway; Potassium; Potassium Channels; Propranolol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sympatholytics | 1997 |
Surface residue mutations of the PML RING finger domain alter the formation of nuclear matrix-associated PML bodies.
Topics: 3T3 Cells; Animals; Glutamic Acid; HeLa Cells; Humans; Lysine; Mice; Mutagenesis, Site-Directed; Neoplasm Proteins; Nuclear Matrix; Nuclear Proteins; Promyelocytic Leukemia Protein; Protein Structure, Tertiary; Static Electricity; Transcription Factors; Transfection; Tumor Suppressor Proteins; Zinc Fingers | 1997 |
Intersubunit communication in hybrid hexamers of K89L/A163G/S380A and C320S mutants of glutamate dehydrogenase from Clostridium symbiosum.
Topics: Alanine; Allosteric Regulation; Clostridium; Dithionitrobenzoic Acid; Glutamate Dehydrogenase; Glutamic Acid; Lysine; NAD; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Proteins; Serine | 1997 |
Alignment of fibrillin molecules in elastic microfibrils is defined by transglutaminase-derived cross-links.
Topics: Acrylonitrile; Actin Cytoskeleton; Amino Acid Sequence; Amino Acids; Amnion; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Electrophoresis, Capillary; Fibrillin-1; Fibrillins; Glutamic Acid; Humans; Lysine; Microfilament Proteins; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Sequence Analysis; Transglutaminases; Trypsin | 1997 |
Cytoplasmic regions of the alpha subunit of the sodium pump involved in modulating the Na,K-ATPase reaction.
Topics: Adenosine Triphosphate; Animals; Cytoplasm; Glutamic Acid; Kinetics; Lysine; Macromolecular Substances; Models, Chemical; Mutagenesis, Site-Directed; Phosphoproteins; Protein Conformation; Protein Structure, Secondary; Rats; Recombinant Fusion Proteins; Sequence Deletion; Sodium; Sodium-Potassium-Exchanging ATPase | 1997 |
The PsaD subunit of photosystem I. Mutations in the basic domain reduce the level of PsaD in the membranes.
Topics: Amino Acid Sequence; Amino Acid Substitution; DNA Primers; Glutamic Acid; Glutamine; Kinetics; Lysine; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Photosystem I Protein Complex; Plant Proteins; Polymerase Chain Reaction; Protein Structure, Secondary; Sequence Alignment; Sequence Homology, Amino Acid | 1997 |
The monovalent cation requirement of rabbit muscle pyruvate kinase is eliminated by substitution of lysine for glutamate 117.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cations, Monovalent; Corynebacterium; Enzyme Activation; Escherichia coli; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Muscles; Mutagenesis, Site-Directed; Potassium; Pyruvate Kinase; Rabbits; Recombinant Proteins; Sequence Homology, Amino Acid | 1997 |
A novel mutation (E358K) in the alpha-galactosidase A gene detected in a Japanese family with Fabry disease.
Topics: Adolescent; Adult; alpha-Galactosidase; Amino Acid Substitution; Base Sequence; DNA; DNA Mutational Analysis; Fabry Disease; Family Health; Female; Glutamic Acid; Humans; Japan; Lysine; Male; Mutation; Pedigree; Point Mutation | 1998 |
[Conformational states of cyclic dipeptides with lactam bond between omega-functions of lysine and aspartic or glutamic acid residues].
Topics: Aspartic Acid; Circular Dichroism; Computer Simulation; Dipeptides; Glutamic Acid; Lactams; Lysine; Magnetic Resonance Spectroscopy; Peptides, Cyclic; Protein Conformation | 1997 |
Molecular screening of Batten disease: identification of a missense mutation (E295K) in the CLN3 gene.
Topics: Alternative Splicing; Amino Acid Sequence; Amino Acid Substitution; Animals; Dogs; Gene Deletion; Genetic Testing; Glutamic Acid; Humans; Lysine; Membrane Glycoproteins; Mice; Molecular Chaperones; Molecular Sequence Data; Neuronal Ceroid-Lipofuscinoses; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proteins | 1998 |
Hb Tak confirmed by DNA analysis: not expressed as thalassemia in a Hb Tak/Hb E compound heterozygote.
Topics: Adult; Amino Acid Substitution; Cambodia; Genetic Carrier Screening; Glutamic Acid; Hemoglobin A; Hemoglobin E; Hemoglobins, Abnormal; Humans; Lysine; Male; Mutation; Sequence Analysis, DNA; Thalassemia | 1998 |
A novel Glu421Lys substitution in the lipoprotein lipase gene in pregnancy-induced hypertriglyceridemic pancreatitis.
Topics: Adult; Catalysis; Fatal Outcome; Female; Glutamic Acid; Heterozygote; Humans; Hypertriglyceridemia; Lipoprotein Lipase; Lysine; Pancreatitis; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pregnancy; Pregnancy Complications | 1998 |
Compensation for D-glutamate auxotrophy of Escherichia coli WM335 by D-amino acid aminotransferase gene and regulation of murI expression.
Topics: Alanine Transaminase; Amino Acid Isomerases; Asparagine; Culture Media; D-Alanine Transaminase; Escherichia coli; Gene Expression; Glutamic Acid; Lysine; Mutagenesis, Site-Directed | 1998 |
Validation of an HPLC method for the analysis of the charge heterogeneity of the recombinant monoclonal antibody IDEC-C2B8 after papain digestion.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Glutamic Acid; Hot Temperature; Humans; Hydrogen-Ion Concentration; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Lysine; Papain; Recombinant Proteins; Reproducibility of Results; Rituximab | 1997 |
Lysine and arginine residues in the N-terminal 18% of apolipoprotein B are critical for its binding to microsomal triglyceride transfer protein.
Topics: Apolipoproteins B; Arginine; Aspartic Acid; Binding Sites; Carrier Proteins; Cell Line; Glutamic Acid; Heparin; Histidine; Humans; Lysine; Microsomes; Protein Binding; Receptors, LDL | 1998 |
A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor.
Topics: Alleles; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Conserved Sequence; Foxes; Genes, Dominant; Glutamic Acid; Hair Color; Histidine; Ligands; Lysine; Mice; Models, Genetic; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Receptors, Corticotropin; Receptors, Melanocortin; Sheep | 1998 |
Identifying Lys359 as a critical residue for the ATP-dependent reactions of Drosophila DNA topoisomerase II.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Binding Sites; DNA; DNA Topoisomerases, Type II; DNA, Circular; Drosophila; Glutamic Acid; Glutamine; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity | 1998 |
Mechanical properties of a self-assembling oligopeptide matrix.
Topics: Biomechanical Phenomena; Glutamic Acid; Lysine; Mathematics; Microscopy, Electron, Scanning; Oligopeptides; Phenylalanine; Tensile Strength | 1998 |
Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
Topics: Alanine; Alkylating Agents; Amino Acid Substitution; Carbamates; Crystallization; Crystallography, X-Ray; Disulfides; Glutamic Acid; Klebsiella pneumoniae; Ligands; Lysine; Mutagenesis, Site-Directed; Nickel; Sulfhydryl Compounds; Urease | 1998 |
Characterization of D10S and K71E mutants of human cytosolic hsp70.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aspartic Acid; Clathrin; Cytochrome c Group; Cytosol; Glutamic Acid; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Lysine; Mutagenesis, Insertional; Nucleotides; Peptides; Recombinant Proteins; Serine | 1998 |
Novel anti-brain tumor cytotoxins specific for cancer cells.
Topics: Antineoplastic Agents; Brain Neoplasms; Carrier Proteins; Cell Division; Cytotoxins; Exotoxins; Glioma; Glutamic Acid; Humans; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Lysine; Mutation; Plasmids; Pseudomonas aeruginosa; Receptors, Cell Surface; Receptors, Interleukin; Receptors, Interleukin-13; Recombinant Fusion Proteins; Tumor Cells, Cultured | 1998 |
A single amino-acid substitution in gag p19 protein (MA) of Rous sarcoma virus suppresses virus production from infected cells.
Topics: Amino Acid Substitution; Animals; Avian Sarcoma Viruses; Capsid; Chick Embryo; Gene Products, gag; Glutamic Acid; Lysine; Point Mutation; RNA-Directed DNA Polymerase; Virus Replication | 1998 |
A novel mutation of the human luteinizing hormone receptor in 46XY and 46XX sisters.
Topics: Adolescent; Adult; Cell Line; Chorionic Gonadotropin; Consanguinity; Embryo, Mammalian; Estradiol; Female; Glutamic Acid; Homozygote; Humans; Kidney; Luteinizing Hormone; Lysine; Male; Mutagenesis, Site-Directed; Mutation; Pedigree; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Protein Structure, Secondary; Receptors, LH; Sequence Analysis, DNA; Testosterone; Transfection | 1998 |
Glutamate-459 is important for Escherichia coli branching enzyme activity.
Topics: 1,4-alpha-Glucan Branching Enzyme; Alanine; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Conserved Sequence; Escherichia coli; Glutamic Acid; Glutamine; Glycogen; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Plant Proteins; Sequence Alignment | 1998 |
Evidence that the conformation of unliganded human plasminogen is maintained via an intramolecular interaction between the lysine-binding site of kringle 5 and the N-terminal peptide.
Topics: Amino Acid Substitution; Aminocaproic Acid; Animals; Binding Sites; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Enzyme Activation; Glutamic Acid; Humans; Kringles; Ligands; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Plasminogen; Protein Conformation; Recombinant Proteins; Urokinase-Type Plasminogen Activator | 1998 |
Effects of single and double mutations in plastocyanin on the rate constant and activation parameters for the rearrangement gating the electron-transfer reaction between the triplet state of zinc cytochrome c and cupriplastocyanin.
Topics: Animals; Copper; Cytochrome c Group; Cytochromes c; Electron Transport; Enzyme Activation; Glutamic Acid; Glutamine; Horses; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Photolysis; Plastocyanin; Spectrophotometry; Spinacia oleracea; Temperature; Viscosity; Zinc | 1998 |
A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.
Topics: Adult; Child, Preschool; Female; Glutamic Acid; Hair Diseases; Humans; Keratins; Lysine; Phenotype; Point Mutation | 1998 |
A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function.
Topics: Amino Acid Substitution; Animals; Anions; Binding Sites; Biological Transport, Active; Carrier Proteins; Drug Resistance, Neoplasm; Folic Acid; Glutamic Acid; Kinetics; Leukemia L1210; Lysine; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Mice; Mutagenesis, Site-Directed; Protein Structure, Secondary; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |
Glu78, from the conserved PEWY sequence of subunit IV, has a key function in cytochrome b6f turnover.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Chlamydomonas reinhardtii; Chloroplasts; Conserved Sequence; Cytochrome b Group; Cytochrome b6f Complex; Electron Transport; Glutamic Acid; Glutamine; Kinetics; Leucine; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptide Fragments; Transformation, Genetic | 1998 |
Neutralization of conservative charged transmembrane residues in the Na+/glucose cotransporter SGLT1.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Binding, Competitive; Biological Transport; Glucose; Glutamic Acid; Kinetics; Lysine; Membrane Glycoproteins; Models, Molecular; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Phlorhizin; Protein Structure, Secondary; Rabbits; Sodium; Sodium-Glucose Transporter 1 | 1998 |
Unfolding of titin immunoglobulin domains by steered molecular dynamics simulation.
Topics: Amino Acid Sequence; Animals; Computer Simulation; Connectin; Glutamic Acid; Immunoglobulins; Lysine; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Muscle Proteins; Myocardium; Proline; Protein Denaturation; Protein Folding; Protein Kinases; Protein Structure, Secondary; Sequence Alignment; Sequence Homology, Amino Acid; Valine | 1998 |
Engineering the S1' subsite of trypsin: design of a protease which cleaves between dibasic residues.
Topics: Amino Acids, Diamino; Animals; Arginine; Aspartic Acid; Binding Sites; Crystallography, X-Ray; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Engineering; Rats; Structure-Activity Relationship; Substrate Specificity; Trypsin | 1998 |
Interaction site for soluble cytochromes on the tetraheme cytochrome subunit bound to the bacterial photosynthetic reaction center mapped by site-directed mutagenesis.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Cytochromes; Cytochromes c; Electron Transport; Glutamic Acid; Heme; Light-Harvesting Protein Complexes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Protein Binding; Rhodospirillaceae; Solubility; Spectrophotometry; Static Electricity | 1998 |
PEVK extension of human soleus muscle titin revealed by immunolabeling with the anti-titin antibody 9D10.
Topics: Animals; Antibodies; Cells, Cultured; Connectin; Glutamic Acid; Humans; Immunoglobulins; Lysine; Microscopy, Immunoelectron; Muscle Proteins; Muscle, Skeletal; Myocardium; Peptide Fragments; Proline; Protein Kinases; Rats; Sarcomeres; Valine | 1998 |
A survey of the primary structure and the interspecies conservation of I-band titin's elastic elements in vertebrates.
Topics: Amino Acid Sequence; Animals; Connectin; Conserved Sequence; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Muscle Proteins; Proline; Protein Kinases; Sequence Alignment; Species Specificity; Valine | 1998 |
Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Calcium; Chemokine CCL8; Chemotaxis, Leukocyte; Cloning, Molecular; Dipeptidyl Peptidase 4; DNA, Complementary; Escherichia coli; Genetic Vectors; Glutamic Acid; Humans; Lysine; Male; Molecular Sequence Data; Monocyte Chemoattractant Proteins; Open Reading Frames; Protein Isoforms; Protein Processing, Post-Translational; Pyrrolidonecarboxylic Acid; Receptors, CCR5; Recombinant Proteins; Sequence Analysis, DNA; Signal Transduction; Testis; Tumor Cells, Cultured | 1998 |
Elucidation of the structural basis for the slow reactivity of thrombin with plasminogen activator inhibitor-1.
Topics: Amino Acid Sequence; Amino Acid Substitution; Glutamic Acid; Glutamine; Humans; Kinetics; Lysine; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Plasminogen Activator Inhibitor 1; Sequence Alignment; Structure-Activity Relationship; Thrombin; Tissue Plasminogen Activator; Trypsin | 1998 |
Redox properties of human medium-chain acyl-CoA dehydrogenase, modulation by charged active-site amino acid residues.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Amino Acid Substitution; Binding Sites; Energy Transfer; Glutamic Acid; Glycine; Humans; Hydrogen-Ion Concentration; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Recombinant Proteins; Spectrophotometry | 1998 |
Lysine and glutamate transport in the erythrocytes of common brushtail possum, Tammar Wallaby and eastern grey, kangaroo.
Topics: Amino Acids; Animals; Biological Transport; Erythrocytes; Glutamic Acid; Lysine; Macropodidae; Opossums | 1998 |
Carbon-13 isotope effect studies of Trypanosoma brucei ornithine decarboxylase.
Topics: Animals; Binding Sites; Carbon Isotopes; Chromatography, High Pressure Liquid; Decarboxylation; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Ornithine; Ornithine Decarboxylase; Recombinant Fusion Proteins; Schiff Bases; Substrate Specificity; Trypanosoma brucei brucei | 1998 |
Hemoglobin Agenogi [beta 90 (F6) Glu-->Lys] found in Piedmont. Case report.
Topics: Adult; Female; Glutamic Acid; Hemoglobins, Abnormal; Humans; Lysine; Mutation | 1998 |
Orientation, positional, additivity, and oligomerization-state effects of interhelical ion pairs in alpha-helical coiled-coils.
Topics: Amino Acid Sequence; Amino Acid Substitution; Drug Stability; Glutamic Acid; Hydrogen-Ion Concentration; Ions; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Osmolar Concentration; Peptides; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Static Electricity; Thermodynamics | 1998 |
A glutamate to lysine mutation at the end of 2B rod domain of keratin 2e gene in ichthyosis bullosa of Siemens.
Topics: Amino Acid Substitution; Base Sequence; Child, Preschool; Codon; Conserved Sequence; Epidermis; Exons; Glutamic Acid; Humans; Hyperkeratosis, Epidermolytic; Ichthyosis; Keratin-2; Keratins; Lysine; Male; Microscopy, Electron; Point Mutation; Polymerase Chain Reaction; Sequence Analysis, DNA | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
Site-directed mutagenesis of putative active site residues of 5-enolpyruvylshikimate-3-phosphate synthase.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alanine; Alkyl and Aryl Transferases; Amino Acid Substitution; Arginine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Escherichia coli; Glutamic Acid; Lysine; Mutagenesis, Site-Directed; Plasmids; Recombinant Proteins | 1999 |
Complex formation between Azotobacter vinelandii ferredoxin I and its physiological electron donor NADPH-ferredoxin reductase.
Topics: Amino Acid Sequence; Anabaena; Azotobacter vinelandii; Circular Dichroism; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ferredoxin-NADP Reductase; Ferredoxins; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; NADP; Protein Conformation; Pseudomonas aeruginosa; Static Electricity | 1999 |
Site-directed mutagenesis of charged and potentially proton-carrying residues in the beta subunit of the proton-translocating nicotinamide nucleotide transhydrogenase from Escherichia coli. Characterization of the beta H91, beta D392, and beta K424 mutant
Topics: Aspartic Acid; Biological Transport; Catalysis; Conserved Sequence; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Lysine; Magnesium Chloride; Mutagenesis, Site-Directed; NADP; NADP Transhydrogenases; Proton Pumps; Recombinant Proteins; Sodium Chloride | 1999 |
Interaction of the N-terminus of chicken skeletal essential light chain 1 with F-actin.
Topics: Actins; Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Carbodiimides; Chickens; Cross-Linking Reagents; Glutamic Acid; Lysine; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Myosin Light Chains; Peptide Fragments; Proline; Sequence Deletion | 1999 |
Interaction site for high-potential iron-sulfur protein on the tetraheme cytochrome subunit bound to the photosynthetic reaction center of Rubrivivax gelatinosus.
Topics: Bacterial Proteins; Binding Sites; Cytochromes; Electron Transport; Glutamic Acid; Heme; Iron-Sulfur Proteins; Light-Harvesting Protein Complexes; Lysine; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Rhodospirillaceae; Valine | 1999 |
Analysis of the functional coupling between calmodulin's calcium binding and peptide recognition properties.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium; Calmodulin; Chickens; Enzyme Activation; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Myosin-Light-Chain Kinase; Peptides; Protein Binding; Protein Folding | 1999 |
Raman markers of nonaromatic side chains in an alpha-helix assembly: Ala, Asp, Glu, Gly, Ile, Leu, Lys, Ser, and Val residues of phage fd subunits.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Deuterium; DNA, Single-Stranded; Glutamic Acid; Glycine; Inovirus; Isoleucine; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Serine; Spectrum Analysis, Raman; Valine; Viral Proteins; Virus Assembly | 1999 |
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase.
Topics: Alanine Racemase; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Geobacillus stearothermophilus; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Protons; Pyridoxal Phosphate; Schiff Bases; Solvents; Tyrosine | 1999 |
Double-mutant analysis of the interaction of Ras with the Ras-binding domain of RGL.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Glutamic Acid; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Histidine; Humans; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; ras Proteins; Rats; Recombinant Fusion Proteins; Static Electricity; Tyrosine | 1999 |
Androgen receptor gene mutations in 46,XY females with germ cell tumours.
Topics: Adolescent; Adult; Binding Sites; Codon; DNA; Dysgerminoma; Exons; Germinoma; Glutamic Acid; Gonadoblastoma; Humans; Lysine; Male; Mutation; Phenotype; Point Mutation; Receptors, Androgen; Testicular Neoplasms | 1999 |
Site-directed mutagenesis of human dihydrolipoamide dehydrogenase: role of lysine-54 and glutamate-192 in stabilizing the thiolate-FAD intermediate.
Topics: Base Sequence; Circular Dichroism; Dihydrolipoamide Dehydrogenase; DNA Primers; Electron Transport; Enzyme Stability; Escherichia coli; Flavin-Adenine Dinucleotide; Genetic Vectors; Glutamic Acid; Humans; In Vitro Techniques; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NAD; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence | 1999 |
Newly formed excitatory pathways provide a substrate for hyperexcitability in experimental temporal lobe epilepsy.
Topics: Animals; Axons; Dendrites; Electrophysiology; Epilepsy, Temporal Lobe; Glutamic Acid; Hippocampus; Image Processing, Computer-Assisted; Lysine; Male; Nerve Net; Neural Pathways; Neuronal Plasticity; Neurons; Pyramidal Cells; Rats; Rats, Wistar; Seizures; Synapses | 1999 |
Early arrest in B cell development in transgenic mice that express the E41K Bruton's tyrosine kinase mutant under the control of the CD19 promoter region.
Topics: Agammaglobulinaemia Tyrosine Kinase; Agammaglobulinemia; Animals; Antigens, CD19; B-Lymphocyte Subsets; Cell Differentiation; Gene Expression Regulation; Glutamic Acid; Humans; Immunoglobulin G; Immunoglobulin M; Immunophenotyping; Lymphopenia; Lysine; Mice; Mice, Transgenic; Plasma Cells; Point Mutation; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Spleen; Transgenes | 1999 |
Direct effects on antigen-presenting cells and T lymphocytes explain the adjuvanticity of a nontoxic cholera toxin mutant.
Topics: Adjuvants, Immunologic; Animals; Antigen-Presenting Cells; Antigens, CD; Apoptosis; B7-1 Antigen; B7-2 Antigen; CD4-Positive T-Lymphocytes; Cholera Toxin; Cytokines; Glutamic Acid; Lymphocyte Activation; Lysine; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mutagenesis, Site-Directed; Signal Transduction | 1999 |
Role of the ATP-binding domain of the human papillomavirus type 11 E1 helicase in E2-dependent binding to the origin.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Animals; Binding Sites; Cattle; DNA Helicases; DNA Replication; DNA-Binding Proteins; Glutamic Acid; Glutamine; Humans; Lysine; Magnesium; Papillomaviridae; Proline; Replication Origin; Saccharomyces cerevisiae; Serine; Temperature; Viral Proteins; Virus Replication | 1999 |
Folding mechanism of Pseudomonas aeruginosa cytochrome c551: role of electrostatic interactions on the hydrophobic collapse and transition state properties.
Topics: Bacterial Proteins; Cytochrome c Group; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Protein Conformation; Protein Folding; Pseudomonas aeruginosa; Static Electricity | 1999 |
The alpha-helix folds on the millisecond time scale.
Topics: Animals; Glutamic Acid; Humans; Kinetics; Lysine; Protein Folding; Proteins; Time Factors | 1999 |
Identification of an HLA-A11 serological variant and its characterization by sequencing based typing.
Topics: Alleles; Amino Acid Substitution; Female; Glutamic Acid; Histocompatibility Testing; HLA-A Antigens; HLA-A11 Antigen; Humans; Lysine; Male; Molecular Sequence Data; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sequence Analysis, DNA; White People | 1999 |
Glutamic acid 472 and lysine 480 of the sodium pump alpha 1 subunit are essential for activity. Their conservation in pyrophosphatases suggests their involvement in recognition of ATP phosphates.
Topics: Acrylamides; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Cnidarian Venoms; Conserved Sequence; Enzyme Activation; Glutamic Acid; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Ouabain; Phosphates; Pyrophosphatases; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Sheep; Sodium-Potassium-Exchanging ATPase | 1999 |
Electrochemical, FTIR, and UV/VIS spectroscopic properties of the ba(3) oxidase from Thermus thermophilus.
Topics: Arginine; Aspartic Acid; Buffers; Cytochrome b Group; Deuterium Oxide; Electrochemistry; Electron Transport Complex IV; Glutamic Acid; Heme; Lysine; Oxidation-Reduction; Peptides; Phosphates; Porphyrins; Potentiometry; Propionates; Protein Conformation; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Thermus thermophilus; Tyrosine; Water | 1999 |
Receptor activation by human C5a des Arg74 but not intact C5a is dependent on an interaction between Glu199 of the receptor and Lys68 of the ligand.
Topics: Animals; Antigens, CD; Arginine; Aspartic Acid; Complement C5a, des-Arginine; Glutamic Acid; Hexosaminidases; Humans; Iodine Radioisotopes; Ligands; Lysine; Monocytes; Mutagenesis, Site-Directed; Peptide Fragments; Rats; Receptor, Anaphylatoxin C5a; Receptors, Complement; Recombinant Proteins; Transfection; Tumor Cells, Cultured; U937 Cells | 1999 |
Neocortical projections regulate the neostriatal proenkephalin gene expression.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Enkephalins; Gene Expression Regulation; Glutamic Acid; In Situ Hybridization; In Vitro Techniques; Kinetics; Lysine; Neocortex; Neostriatum; Nerve Fibers; Neural Pathways; Protein Precursors; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1999 |
Transport of amino acids and ammonium in mycelium of Agaricus bisporus.
Topics: Agaricus; Amino Acids; Arginine; Biological Transport; Carbon Radioisotopes; Culture Media; Glutamic Acid; Glutamine; Histidine; Kinetics; Lysine; Methylamines; Quaternary Ammonium Compounds | 1999 |
Characterization of residues in human IgE and IgG binding site by chemical modification of ovomucoid third domain.
Topics: Acylation; Alkylation; Aspartic Acid; Binding Sites; Child, Preschool; Circular Dichroism; Female; Glutamic Acid; Histidine; Humans; Immunoglobulin E; Immunoglobulin G; Infant; Lysine; Ovomucin; Protein Structure, Secondary; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1999 |
An aggressive familial amyloidotic polyneuropathy caused by a new variant transthyretin Lys 54.
Topics: Adult; Age of Onset; Amyloid Neuropathies; Chromosome Mapping; Glutamic Acid; Humans; Immunohistochemistry; Japan; Lysine; Male; Polymerase Chain Reaction; Prealbumin; Sural Nerve | 1999 |
The influence of Carisolv on enamel and dentine surface topography.
Topics: Acid Etching, Dental; Dental Caries; Dental Cavity Preparation; Dental Enamel; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Atomic Force; Phosphoric Acids | 1999 |
Interactions of calcineurin A, calcineurin B, and Ca2+.
Topics: Amino Acid Sequence; Animals; Calcineurin; Calcium; Calcium Radioisotopes; Calcium-Binding Proteins; Cattle; Dimerization; Enzyme Activation; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments | 1999 |
Peroxynitrite anion stimulates arginine release from cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Arginine; Astrocytes; Cells, Cultured; Citrulline; Glutamic Acid; Hydrogen Peroxide; Kinetics; Lysine; Nitrates; Nitric Oxide Donors; Oxidants; Rats; Rats, Wistar; Serine | 1999 |
Endogenous activation of metabotropic glutamate receptors in neocortical development causes neuronal calcium oscillations.
Topics: Animals; Calcium; Cycloleucine; Excitatory Amino Acid Agonists; Glutamic Acid; Lysine; Mice; Microscopy, Fluorescence; N-Methylaspartate; Neocortex; Neuroglia; Neurons; Neuroprotective Agents; Protein Isoforms; Receptors, Metabotropic Glutamate; Time Factors | 1999 |
Oligomerization of the EK18 mutant of the trp repressor of Escherichia coli as observed by NMR spectroscopy.
Topics: Amino Acid Substitution; Apoproteins; Bacterial Proteins; Crystallography, X-Ray; DNA, Bacterial; Escherichia coli; Glutamic Acid; Lysine; Macromolecular Substances; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Protein Conformation; Repressor Proteins | 1999 |
Effect of a chemo-mechanical caries removal system (Carisolv) on dentin topography of non-carious dentin.
Topics: Acid Etching, Dental; Adult; Bicuspid; Dental Caries; Dental Cavity Preparation; Dentin; Drug Evaluation, Preclinical; Glutamic Acid; Humans; In Vitro Techniques; Leucine; Lysine; Microscopy, Electron, Scanning; Random Allocation; Surface Properties | 1999 |
The flattened face of type II beta phosphatidylinositol phosphate kinase binds acidic phospholipid membranes.
Topics: 1-Phosphatidylinositol 4-Kinase; Binding Sites; Enzyme Activation; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Lipid Bilayers; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phospholipids; Protein Binding; Recombinant Fusion Proteins; Static Electricity; Ultracentrifugation | 1999 |
The E249K mutator mutant of DNA polymerase beta extends mispaired termini.
Topics: Amino Acid Substitution; Base Sequence; DNA; DNA Polymerase beta; DNA Primers; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Mutagenesis; Nucleic Acid Conformation; Phenotype; Protein Structure, Secondary; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase; Zidovudine | 1999 |
Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface.
Topics: Amino Acid Substitution; Arginine; Asparagine; Circular Dichroism; Glutamic Acid; Glutamine; Histidine; Linear Models; Lysine; Mutagenesis, Site-Directed; Protein Engineering; Protein Folding; Static Electricity; Surface Properties; Thermodynamics; Ubiquitins | 1999 |
Two novel mutations consisting in minor gene rearrangements in the human low density lipoprotein receptor gene in Italian patients affected by familial hypercholesterolemia. Mutations in brief no. 194. Online.
Topics: Amino Acid Substitution; Cysteine; Frameshift Mutation; Glutamic Acid; Humans; Hyperlipoproteinemia Type II; Italy; Lysine; Receptors, LDL | 1998 |
A second-site mutation at glutamate-257 that restores the function of the mutant yeast ribosomal protein L5 containing lysine-270,271-->arginine.
Topics: Amino Acid Sequence; Animals; Arginine; Glutamic Acid; Lysine; Mutagenesis, Site-Directed; Ribosomal Proteins; RNA-Binding Proteins; RNA, Ribosomal, 5S; Saccharomyces cerevisiae; Sequence Homology, Amino Acid | 1999 |
Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase.
Topics: Adenosine Triphosphate; Aspartic Acid; Bacterial Proteins; Binding, Competitive; Catalysis; Chlorides; Conserved Sequence; DNA Mutational Analysis; Escherichia coli Proteins; Glutamic Acid; Glutamine; Kinetics; Lysine; Magnesium; Magnesium Chloride; Manganese; Manganese Compounds; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphoric Monoester Hydrolases; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protons; Pyrophosphatases; Recombinant Proteins; Solvents | 2000 |
Mutagenesis of E477 or K505 in the B' domain of human topoisomerase II beta increases the requirement for magnesium ions during strand passage.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Catalysis; Cations, Divalent; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Fungal; DNA, Superhelical; Genetic Complementation Test; Glutamic Acid; Humans; Hydrolysis; Lysine; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Recombinant Proteins; Saccharomyces cerevisiae | 2000 |
Presence of 2-furoylmethyl derivatives in hydrolysates of processed tomato products.
Topics: Alanine; Asparagine; Aspartic Acid; Chromatography, High Pressure Liquid; Freeze Drying; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Hydrolysis; Lysine; Maillard Reaction; Serine; Solanum lycopersicum; Threonine | 2000 |
Annexin XII E105K crystal structure: identification of a pH-dependent switch for mutant hexamerization.
Topics: Animals; Annexins; Binding Sites; Calcium; Conserved Sequence; Crystallization; Glutamic Acid; Hydra; Hydrogen-Ion Concentration; Lysine; Mutagenesis, Site-Directed; Static Electricity | 2000 |
Solution structure of the sixth LDL-A module of the LDL receptor.
Topics: Amino Acid Sequence; Aspartic Acid; Calcium; Crystallography, X-Ray; Glutamic Acid; Humans; Hyperlipoproteinemia Type II; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Protein Folding; Receptors, LDL; Solutions | 2000 |
Scanning electron microscopic observations of human dentine after mechanical caries excavation.
Topics: Air Abrasion, Dental; Dental Caries; Dental Cavity Preparation; Dentin; Evaluation Studies as Topic; Gels; Glutamic Acid; Humans; In Vitro Techniques; Leucine; Lysine; Mandible; Microscopy, Electron, Scanning; Molar; Sonication; Surface Properties | 2000 |
Efficacy of Carisolv-assisted caries excavation.
Topics: Adult; Dental Caries; Dental Cavity Preparation; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Outcome Assessment, Health Care; Smear Layer | 1999 |
Pharmacological concentrations of arginine influence human whole blood viscosity independent of nitric oxide synthase activity in vitro.
Topics: Adult; Arginine; Blood Viscosity; Glutamic Acid; Hematocrit; Humans; In Vitro Techniques; Kinetics; Lysine; Nitric Oxide Synthase; Nitroarginine; Sodium Chloride; Stereoisomerism | 2000 |
An engineered blockage within the ammonia tunnel of carbamoyl phosphate synthetase prevents the use of glutamine as a substrate but not ammonia.
Topics: Alanine; Ammonia; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carbamyl Phosphate; Escherichia coli; Glutamic Acid; Glutamine; Glycine; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Serine; Substrate Specificity; Time Factors | 2000 |
Noradrenergic regulation of parvocellular neurons in the rat hypothalamic paraventricular nucleus.
Topics: Adrenergic alpha-Agonists; Animals; Brain Mapping; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Lysine; Male; Membrane Potentials; Neural Inhibition; Neurons; Norepinephrine; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 2000 |
Remarkable thermal stability of doubly intramolecularly cross-linked hen lysozyme.
Topics: Amino Acid Substitution; Animals; Binding Sites; Calorimetry, Differential Scanning; Chickens; Egg White; Enzyme Stability; Glutamic Acid; Histidine; Hot Temperature; Lysine; Muramidase; Mutagenesis, Site-Directed; Protein Folding; Recombinant Proteins; Thermodynamics; Tryptophan | 2000 |
Identification of three novel mutations (E196K, V203I, E211Q) in the prion protein gene (PRNP) in inherited prion diseases with Creutzfeldt-Jakob disease phenotype.
Topics: Aged; Amino Acid Substitution; Amyloid; Creutzfeldt-Jakob Syndrome; Female; Glutamic Acid; Glutamine; Humans; Isoleucine; Lysine; Male; Middle Aged; Mutation, Missense; Phenotype; Prion Proteins; Prions; Protein Precursors; Valine | 2000 |
Risk estimation and value-of-information analysis for three proposed genetic screening programs for chronic beryllium disease prevention.
Topics: Berylliosis; Chronic Disease; Cohort Studies; Cost of Illness; Environmental Exposure; Ethics, Medical; Forecasting; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genetic Variation; Glutamic Acid; Health Expenditures; HLA-DP Antigens; Humans; Jurisprudence; Lysine; Occupational Exposure; Polymorphism, Genetic; Prevalence; Probability; Risk Assessment; Risk Management; Sensitivity and Specificity; Social Values | 2000 |
Identification of mutations in rat CD59 that increase the complement regulatory activity.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Asparagine; Binding Sites, Antibody; CD59 Antigens; Cell Line; CHO Cells; Complement Inactivator Proteins; Complement Membrane Attack Complex; Complement Pathway, Classical; Cricetinae; Glutamic Acid; Humans; Lysine; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Rabbits; Rats; Recombinant Proteins; Transfection | 2000 |
Effect of Carisolv solution on sound, demineralized and denatured dentin--an ultrastructural investigation.
Topics: Cariostatic Agents; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron; Protein Denaturation; Tooth Demineralization | 1999 |
On the possibilities and limitations of rational protein design to expand the specificity of restriction enzymes: a case study employing EcoRV as the target.
Topics: Alanine; Amino Acid Substitution; Arginine; Deoxyribonucleases, Type II Site-Specific; Enzyme Activation; Glutamic Acid; Hydrolysis; Lysine; Macromolecular Substances; Oligodeoxyribonucleotides; Protein Engineering; Recombinant Proteins; Substrate Specificity | 2000 |
Mutational analyses of restriction endonuclease-HindIII mutant E86K with higher activity and altered specificity.
Topics: Aspartic Acid; Binding Sites; Cations, Divalent; Circular Dichroism; Deoxyribonuclease HindIII; DNA Mutational Analysis; DNA, Bacterial; Enzyme Activation; Glutamic Acid; Lysine; Mutagenesis, Site-Directed; Plasmids; Polymerase Chain Reaction; Recombinant Proteins; Substrate Specificity | 2000 |
Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus.
Topics: Animals; Axons; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; In Vitro Techniques; Lysine; Male; Oligodendroglia; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Stem Cells; Synapses; Synaptic Transmission | 2000 |
Transcription activation by the Escherichia coli cyclic AMP receptor protein: determinants within activating region 3.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Cloning, Molecular; Cyclic AMP; Cyclic AMP Receptor Protein; DNA-Directed RNA Polymerases; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Reporter; Glutamic Acid; Isomerism; Kinetics; Lysine; Models, Molecular; Multigene Family; Mutation; Promoter Regions, Genetic; Protein Conformation; Static Electricity; Structure-Activity Relationship; Transcription, Genetic; Transcriptional Activation | 2000 |
Isinglass/collagen: denaturation and functionality.
Topics: Air Sacs; Animals; Arginine; Aspartic Acid; Calcium; Calorimetry, Differential Scanning; Cattle; Chelating Agents; Collagen; Decarboxylation; Detergents; Fishes; Gelatin; Glutamic Acid; Hydrogen-Ion Concentration; Hydroxyproline; Lysine; Molecular Weight; Monosaccharides; N-Acetylneuraminic Acid; Osmolar Concentration; Protein Denaturation; Saccharomyces cerevisiae; Temperature | 2000 |
Analyses of Gerstmann-Straussler syndrome with 102Leu219Lys using monoclonal antibodies that specifically detect human prion protein with 219Glu.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Epitope Mapping; Gerstmann-Straussler-Scheinker Disease; Glutamic Acid; Humans; Immunohistochemistry; Leucine; Lysine; Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Prions | 2000 |
Distribution of functional glutamate and GABA receptors on hippocampal pyramidal cells and interneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Cell Polarity; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Interneurons; Lysine; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Rats; Receptors, GABA; Receptors, Glutamate; Synapses | 2000 |
Intercellular adhesion molecule-1 (ICAM-1) K469E polymorphism: no association with type 1 diabetes among Finns.
Topics: Adolescent; Alleles; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Finland; Gene Frequency; Glutamic Acid; Humans; Infant; Infant, Newborn; Intercellular Adhesion Molecule-1; Lysine; Male; Polymorphism, Genetic | 2000 |
Impaired secretion of rat mannose-binding protein resulting from mutations in the collagen-like domain.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Carrier Proteins; CHO Cells; Collagen; Collectins; Complement Fixation Tests; Cricetinae; Cysteine; Endoplasmic Reticulum; Glutamic Acid; Glycine; Humans; Lectins; Lysine; Mannans; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proteins; Rats; Time Factors; Transfection | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Structural and functional study of K453E mutant protective protein/cathepsin A causing the late infantile form of galactosialidosis.
Topics: Amino Acid Substitution; beta-Galactosidase; Blotting, Northern; Carboxypeptidases; Cathepsin A; Child; Crystallography, X-Ray; Female; Glutamic Acid; Humans; Immunohistochemistry; Lysine; Metabolism, Inborn Errors; Models, Molecular; Mutation, Missense; Neuraminidase; Protein Structure, Quaternary; White People | 2000 |
The structure of a CREB bZIP.somatostatin CRE complex reveals the basis for selective dimerization and divalent cation-enhanced DNA binding.
Topics: Amino Acid Sequence; Arginine; Asparagine; Cations; Crystallography, X-Ray; Cyclic AMP Response Element-Binding Protein; Dimerization; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrons; Escherichia coli; Glutamic Acid; Glutamine; Hydrogen Bonding; Ions; Kinetics; Leucine Zippers; Lysine; Magnesium; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Response Elements; Sequence Homology, Amino Acid; Signal Transduction; Somatostatin | 2000 |
Functional significance of conserved residues in the phosphohydrolase module of Escherichia coli MutT protein.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Bacterial Proteins; Base Sequence; Catalytic Domain; Codon; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Glycine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoric Monoester Hydrolases; Pyrophosphatases; Suppression, Genetic; Threonine | 2000 |
Cytochrome c peroxidase-cytochrome c complex: locating the second binding domain on cytochrome c peroxidase with site-directed mutagenesis.
Topics: Animals; Aspartic Acid; Binding Sites; Calorimetry; Cytochrome c Group; Cytochrome-c Peroxidase; Cytochromes c; Glutamic Acid; Horses; Kinetics; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Zinc | 2000 |
Staggered molecular packing in crystals of a collagen-like peptide with a single charged pair.
Topics: Amino Acid Sequence; Biopolymers; Collagen; Crystallography, X-Ray; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyproline; Lysine; Models, Molecular; Molecular Sequence Data; Peptides; Protein Structure, Quaternary; Static Electricity; Water | 2000 |
Catalytic control and coupling efficiency of the Escherichia coli FoF1 ATP synthase: influence of the Fo sector and epsilon subunit on the catalytic transition state.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Biological Transport; Catalysis; Cysteine; Detergents; Dimethylamines; Enzyme Activation; Escherichia coli; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Methionine; Mutagenesis, Site-Directed; Peptide Fragments; Proton-Translocating ATPases; Protons; Tyrosine | 2000 |
Basis for half-of-the-site reactivity and the dominance of the K487 oriental subunit over the E487 subunit in heterotetrameric human liver mitochondrial aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Amino Acid Substitution; Asian People; Binding Sites; Dimerization; Enzyme Activation; Glutamic Acid; Humans; Kinetics; Lysine; Mitochondria, Liver; Mutagenesis, Site-Directed; NAD; Peptide Fragments | 2000 |
Does chemomechanical caries removal affect dentine adhesion?
Topics: Analysis of Variance; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dentin-Bonding Agents; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Random Allocation; Resin Cements; Statistics, Nonparametric; Tensile Strength | 2000 |
A baker's yeast mutant (fil1) with a specific, partially inactivating mutation in adenylate cyclase maintains a high stress resistance during active fermentation and growth.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Amino Acid Substitution; Cyclic AMP; Ethanol; Ethyl Methanesulfonate; Fermentation; Genes, Recessive; Glucose; Glutamic Acid; Kinetics; Lysine; Mutagenesis; Saccharomyces cerevisiae; Sequence Alignment; Temperature | 2000 |
Highly nonproductive complexes with Anabaena ferredoxin at low ionic strength are induced by nonconservative amino acid substitutions at Glu139 in Anabaena ferredoxin:NADP+ reductase.
Topics: Amino Acid Substitution; Anabaena; Circular Dichroism; Conserved Sequence; Ferredoxin-NADP Reductase; Ferredoxins; Glutamic Acid; Glutamine; Kinetics; Lysine; Osmolar Concentration; Oxidation-Reduction; Photolysis; Static Electricity | 2000 |
Streptokinase binds preferentially to the extended conformation of plasminogen through lysine binding site and catalytic domain interactions.
Topics: Amino Acid Chloromethyl Ketones; Aminocaproic Acid; Binding Sites; Catalytic Domain; Chlorides; Fibrinolysin; Glutamic Acid; Humans; Lysine; Plasminogen; Protein Conformation; Serine Proteinase Inhibitors; Streptokinase | 2000 |
Calpain mutants with increased Ca2+ sensitivity and implications for the role of the C(2)-like domain.
Topics: Animals; Calcium; Calpain; Crystallography, X-Ray; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Salts; Serine | 2001 |
A novel mutation E179K of the MEN1 gene predisposes for multiple endocrine neoplasia-type 1 (MEN1).
Topics: Adenoma; Adolescent; Adult; Amino Acid Substitution; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glutamic Acid; Humans; Hyperinsulinism; Hyperparathyroidism; Insulinoma; Lysine; Male; Multiple Endocrine Neoplasia Type 1; Mutation, Missense; Nuclear Family; Pancreatic Neoplasms | 2000 |
Heparan sulfate biosynthesis: a theoretical study of the initial sulfation step by N-deacetylase/N-sulfotransferase.
Topics: Amidohydrolases; Amino Acid Sequence; Catalytic Domain; Crystallography, X-Ray; Glutamic Acid; Heparitin Sulfate; Kinetics; Lysine; Molecular Sequence Data; Sequence Alignment; Sequence Homology, Amino Acid; Sulfotransferases; Threonine | 2000 |
Mutagenic analysis of functional residues in putative substrate-binding site and acidic domains of vacuolar H+-pyrophosphatase.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Binding Sites; Catalytic Domain; Cell Membrane; Conserved Sequence; DNA Mutational Analysis; DNA, Complementary; Gene Library; Glutamic Acid; Hydrolysis; Inorganic Pyrophosphatase; Lysine; Magnesium; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plant Proteins; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protons; Pyrophosphatases; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Trypsin; Vacuoles | 2001 |
Autosomal dominant myopathy: missense mutation (Glu-706 --> Lys) in the myosin heavy chain IIa gene.
Topics: Adult; Amino Acid Sequence; Animals; Child; Female; Genetic Diseases, Inborn; Glutamic Acid; Humans; Lysine; Male; Microscopy, Electron; Middle Aged; Molecular Sequence Data; Molecular Structure; Muscular Diseases; Mutation, Missense; Myosin Heavy Chains; Myosins; NADH Tetrazolium Reductase; Pedigree; Staining and Labeling | 2000 |
Increasing the thermal stability of euphauserase. A cold-active and multifunctional serine protease from Antarctic krill.
Topics: Animals; Antarctic Regions; Aspartic Acid; Autolysis; Crustacea; Enzyme Stability; Glutamic Acid; Lysine; Models, Molecular; Multienzyme Complexes; Phenylalanine; Point Mutation; Protein Conformation; Serine Endopeptidases; Temperature | 2001 |
Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain.
Topics: Amino Acid Substitution; Androstadienes; Animals; Arginine; Blood Proteins; Cysteine; Enzyme Inhibitors; Glutamic Acid; Humans; Interleukin-2; Jurkat Cells; Lysine; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Sequence Homology, Amino Acid; Signal Transduction; T-Lymphocytes; Transfection; Wortmannin | 2001 |
Site-directed mutants of glycogen phosphorylase are altered in their interaction with phosphorylase kinase.
Topics: Amino Acid Substitution; Animals; Arginine; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Kinetics; Lysine; Muscle, Skeletal; Mutagenesis, Site-Directed; Peptide Fragments; Phosphorylase b; Phosphorylase Kinase; Phosphorylases; Phosphorylation; Rabbits; Recombinant Proteins | 2000 |
DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity.
Topics: Animals; Arginine; Asparagine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Deoxyribonucleotides; DNA Polymerase beta; DNA-Binding Proteins; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Rats; Recombinant Proteins; Serine; Structure-Activity Relationship; Templates, Genetic | 2000 |
Identification of active site residues in E. coli ketopantoate reductase by mutagenesis and chemical rescue.
Topics: Acetic Acid; Alanine; Alcohol Oxidoreductases; Alkylation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Cysteine; Deuterium; Escherichia coli; Formates; Gene Expression Regulation, Bacterial; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Pantothenic Acid; Recombinant Proteins; Sequence Alignment; Substrate Specificity | 2000 |
Relationship between NO synthesis, arginine transport, and intracellular arginine levels in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arginine; Aspartic Acid; Biological Transport; Cells, Cultured; Female; Glutamic Acid; Glutamine; Interleukin-1; Lysine; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Ornithine; Rats; Rats, Long-Evans | 2000 |
Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor.
Topics: Alanine; Animals; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Chlorides; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Glutamic Acid; Histidine; Humans; Immunoblotting; Inhibitory Concentration 50; Inositol Phosphates; Ions; Kinetics; Ligands; Lysine; Models, Molecular; Mutation; Plasmids; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Metabotropic Glutamate; Transfection; Zinc; Zinc Compounds | 2001 |
Identification of residues in the carboxy-terminal domain of Clostridium perfringens alpha-toxin (phospholipase C) which are required for its biological activities.
Topics: Amino Acid Substitution; Aspartic Acid; Bacterial Toxins; Calcium-Binding Proteins; Clostridium perfringens; DNA, Bacterial; Egg Yolk; Glutamic Acid; Glycine; Hemolysis; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Phospholipids; Phosphorylcholine; Protein Conformation; Serine; Substrate Specificity; Type C Phospholipases | 2000 |
Interactions between yeast iso-1-cytochrome c and its peroxidase.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Binding Sites; Calorimetry; Crystallography, X-Ray; Cytochrome c Group; Cytochrome-c Peroxidase; Cytochromes c; Glutamic Acid; Lysine; Macromolecular Substances; Mutagenesis, Site-Directed; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Solutions; Thermodynamics; Valine | 2001 |
Effects of toxins Pi2 and Pi3 on human T lymphocyte Kv1.3 channels: the role of Glu7 and Lys24.
Topics: Amino Acid Sequence; Animals; Charybdotoxin; Glutamic Acid; Humans; In Vitro Techniques; Kinetics; Kv1.3 Potassium Channel; Lysine; Membrane Potentials; Models, Molecular; Molecular Sequence Data; Point Mutation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Conformation; Scorpion Venoms; Sequence Homology, Amino Acid; T-Lymphocytes | 2001 |
Engineered antibodies with increased activity to recruit complement.
Topics: Amino Acid Substitution; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antibody-Dependent Cell Cytotoxicity; Antigens, CD20; Binding Sites, Antibody; Carbohydrates; Cell Line, Transformed; Complement Activation; Complement C1q; Glutamic Acid; Glycosylation; Humans; Immunoglobulin G; Immunoglobulin Isotypes; Lysine; Mutagenesis, Site-Directed; Rituximab | 2001 |
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.
Topics: Alanine; Anti-HIV Agents; Aspartic Acid; Cell Line; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; Glutamic Acid; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Mutagenesis, Site-Directed; Nucleosides; Phenylalanine; Recombination, Genetic; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Thymidine; Tyrosine; Uridine | 2001 |
The essential amino acid lysine acts as precursor of glutamate in the mammalian central nervous system.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Gene Expression Profiling; Glutamic Acid; In Situ Hybridization; Lysine; Mice; Neurons; RNA, Messenger; Saccharopine Dehydrogenases | 2001 |
Critical role of glutamic acid 202 in the enzymatic activity of stromelysin-1 (MMP-3).
Topics: Alanine; Aspartic Acid; Binding Sites; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Fibrinolysin; Glutamic Acid; Humans; Hydrolysis; Kinetics; Lysine; Matrix Metalloproteinase 3; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylmercuric Acetate; Plasminogen; Protein Binding; Protein Structure, Tertiary; Sequence Analysis, DNA; Time Factors; Urokinase-Type Plasminogen Activator; Zinc | 2001 |
Site-directed mutagenesis of cytochrome P450scc (CYP11A1). Effect of lysine residue substitution on its structural and functional properties.
Topics: Adrenodoxin; Amino Acid Sequence; Animals; Cholesterol Side-Chain Cleavage Enzyme; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Heme; Humans; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Folding; Sequence Homology, Amino Acid; Spectrophotometry; Thermodynamics; Time Factors | 2000 |
Occurrence of D-Amino Acids and a pyridoxal 5'-phosphate-dependent aspartate racemase in the acidothermophilic archaeon, Thermoplasma acidophilum.
Topics: Alanine; Amino Acid Isomerases; Amino Acids; Aspartic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylmaleimide; Glutamic Acid; Leucine; Lysine; Phenylalanine; Pyridoxal Phosphate; Stereoisomerism; Thermoplasma | 2001 |
Molecular analysis of familial androgen insensitivity syndrome due to replacement of glutamic acid 802 by lysine.
Topics: Adolescent; Amino Acid Substitution; Androgen-Insensitivity Syndrome; Androgens; Exons; Female; Glutamic Acid; Humans; Lysine; Male; Mutation, Missense; Pedigree; Receptors, Androgen | 2000 |
Spontaneous formation of polypeptides in the interfacial thin films of amphiphilic amino acid esters: acceleration of the polycondensation and control of the structure of resultant polymers.
Topics: Alanine; Amino Acids; Esters; Glutamic Acid; Glycine; Indicators and Reagents; Kinetics; Lysine; Peptides; Surface Properties | 2000 |
Poly(amino acid) bioadhesives for tissue repair.
Topics: Adhesiveness; Amino Acids; Animals; Asparagine; Aspartic Acid; Biocompatible Materials; Cartilage; Cattle; Chondroitin Sulfates; Glass; Glutamic Acid; Hydrogen Bonding; Lysine; Materials Testing; Models, Chemical; Models, Molecular; Permeability; Tissue Adhesions; Tissue Adhesives; Wound Healing; Wounds and Injuries | 2000 |
A chemomechanical method for caries removal.
Topics: Dental Caries; Dental Cavity Preparation; Dental Pulp; Dental Restoration, Permanent; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Pain; Patient Satisfaction | 2000 |
Pituitary hormone and insulin responses to infusion of amino acids and N-methyl-D,L-aspartate in horses.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Female; Glutamic Acid; Growth Hormone; Horses; Insulin; Lysine; Male; N-Methylaspartate; Pituitary Hormones; Prolactin; Radioimmunoassay; Thyrotropin | 2001 |
Modeling and experimental design for metabolic flux analysis of lysine-producing Corynebacteria by mass spectrometry.
Topics: Computer Simulation; Corynebacterium; Glucose-6-Phosphate Isomerase; Glutamic Acid; Glycolysis; Lysine; Mass Spectrometry; Models, Biological; Models, Theoretical; Phenylalanine; Pyruvic Acid; Riboflavin; Transaldolase; Transketolase; Valine | 2001 |
Antitumor action of seminal ribonuclease, its dimeric structure, and its resistance to the cytosolic ribonuclease inhibitor.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Antineoplastic Agents; Arginine; Cattle; Cytosol; Dimerization; Disulfides; Drug Resistance; Endoribonucleases; Enzyme Inhibitors; Glutamic Acid; Growth Inhibitors; Lysine; Mice; Mutagenesis, Site-Directed; Proteins; Recombinant Proteins; Semen; Serine; Tryptophan; Tumor Cells, Cultured | 2001 |
A basic residue at position 36p of the propeptide is not essential for the correct folding and subsequent autocatalytic activation of prochymosin.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Catalysis; Cattle; Chymosin; Circular Dichroism; Cloning, Molecular; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Precursors; Escherichia coli; Exons; Glutamic Acid; Hydrogen-Ion Concentration; Isoelectric Focusing; Lysine; Milk; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Pepsinogen A; Peptides; Polymerase Chain Reaction; Protein Folding; Protein Precursors; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Sheep; Time Factors | 2001 |
Superoxide reductase from Desulfoarculus baarsii: reaction mechanism and role of glutamate 47 and lysine 48 in catalysis.
Topics: Animals; Bacterial Proteins; Catalysis; Cattle; Desulfovibrio; Electron Spin Resonance Spectroscopy; Escherichia coli; Genetic Complementation Test; Glutamic Acid; Isoleucine; Kinetics; Lysine; Mutagenesis, Site-Directed; Oxidoreductases; Pulse Radiolysis; Recombinant Proteins; Spectrophotometry; Superoxide Dismutase; Superoxides | 2001 |
Coenzyme specificity in aldehyde dehydrogenase.
Topics: Aldehyde Dehydrogenase; Animals; Binding Sites; Catalytic Domain; Coenzymes; Glutamic Acid; In Vitro Techniques; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADP; Protein Conformation; Protein Denaturation; Rats | 2001 |
Influence of Carisolv for resin adhesion to sound human primary dentin and young permanent dentin.
Topics: Acid Etching, Dental; Analysis of Variance; Bicuspid; Composite Resins; Dental Bonding; Dental Cavity Preparation; Dental Cements; Dentin; Dentin-Bonding Agents; Fluorides, Topical; Glutamic Acid; Humans; Leucine; Lysine; Methacrylates; Microscopy, Electron, Scanning; Molar; Resin Cements; Statistics as Topic; Stress, Mechanical; Surface Properties; Tooth, Deciduous | 2001 |
The amino-terminal tail of glycogen phosphorylase is a switch for controlling phosphorylase conformation, activation, and response to ligands.
Topics: Amino Acid Substitution; Animals; Arginine; Carrier Proteins; Cyclic AMP Receptor Protein; Enzyme Activation; Glutamic Acid; Isoleucine; Ligands; Lysine; Molecular Motor Proteins; Muscle, Skeletal; Peptide Fragments; Phosphorylase a; Phosphorylase b; Phosphorylases; Phosphorylation; Protein Conformation; Rabbits; Structure-Activity Relationship | 2001 |
A novel homozygous mutation in the second transmembrane domain of the gonadotrophin releasing hormone receptor gene.
Topics: Adolescent; Adult; Consanguinity; Female; Follicle Stimulating Hormone; Glutamic Acid; Homozygote; Humans; Hypogonadism; Luteinizing Hormone; Lysine; Male; Mutation, Missense; Pedigree; Receptors, LHRH | 2001 |
Pyruvate carboxylase is a major bottleneck for glutamate and lysine production by Corynebacterium glutamicum.
Topics: Corynebacterium; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Phosphoenolpyruvate Carboxylase; Plasmids; Pyruvate Carboxylase; Recombinant Proteins; Restriction Mapping; Species Specificity; Threonine | 2001 |
Site-specific cation binding mediates TATA binding protein-DNA interaction from a hyperthermophilic archaeon.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Binding Sites; Calorimetry; Cations; DNA-Binding Proteins; Entropy; Glutamic Acid; Lysine; Mutagenesis, Site-Directed; Osmotic Pressure; Pyrococcus; Reproducibility of Results; Salts; TATA Box; TATA-Box Binding Protein; Transcription Factors; Water | 2001 |
Layer-specific intracolumnar and transcolumnar functional connectivity of layer V pyramidal cells in rat barrel cortex.
Topics: Action Potentials; Animals; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Lysine; Male; Neural Pathways; Patch-Clamp Techniques; Photolysis; Pyramidal Cells; Rats; Rats, Wistar; Somatosensory Cortex; Stimulation, Chemical; Synaptic Transmission | 2001 |
Effects of charged amino acids at b and c heptad positions on specificity and stability of four-chain coiled coils.
Topics: Amino Acid Sequence; Circular Dichroism; Enzyme Stability; Glutamic Acid; Lysine; Peptides; Protein Conformation; Protein Structure, Secondary; Static Electricity; Thermodynamics; Ultracentrifugation | 2001 |
Latent specificity of molecular recognition in sodium channels engineered to discriminate between two "indistinguishable" mu-conotoxins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Conotoxins; Glutamic Acid; Glutamine; Lysine; Membrane Potentials; Molecular Sequence Data; Mollusk Venoms; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Binding; Rats; Sodium Channel Blockers; Sodium Channels; Thermodynamics | 2001 |
Derivatization and fluorescence detection of amino acids and peptides with 9-fluorenylmethyl chloroformate on the surface of a solid adsorbent.
Topics: Amino Acids; Chromatography; Chromatography, High Pressure Liquid; Enkephalin, Leucine; Fluorenes; gamma-Aminobutyric Acid; Glutamic Acid; Indicators and Reagents; Lysine; Peptides; Phenylalanine; Reproducibility of Results; Serine; Spectrometry, Fluorescence; Substance P; Valine | 2001 |
The effect of net charge on the solubility, activity, and stability of ribonuclease Sa.
Topics: Aspartic Acid; Circular Dichroism; Escherichia coli; Glutamic Acid; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Denaturation; Ribonucleases; Solubility; Temperature; Thermodynamics | 2001 |
Kinetic preference for oriented DNA binding by the yeast TATA-binding protein TBP.
Topics: Coumarins; Dimerization; DNA-Binding Proteins; DNA, Fungal; Energy Transfer; Fungal Proteins; Glutamic Acid; Kinetics; Lysine; Mutagenesis, Site-Directed; Peptide Chain Initiation, Translational; Protein Binding; Protein Isoforms; Saccharomyces cerevisiae; Spectrometry, Fluorescence; TATA Box; TATA-Box Binding Protein; Transcription Factors; Tryptophan | 2001 |
Beryllium binding to HLA-DP molecule carrying the marker of susceptibility to berylliosis glutamate beta 69.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Berylliosis; Beryllium; Biomarkers; Cell Line; Drosophila melanogaster; Genetic Predisposition to Disease; Genetic Vectors; Glutamic Acid; HLA-DP Antigens; Humans; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Solubility | 2001 |
The effect of the Glu342Lys mutation in alpha1-antitrypsin on its structure, studied by molecular modelling methods.
Topics: alpha 1-Antitrypsin; Glutamic Acid; Humans; Lysine; Models, Molecular; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Software; Temperature; Time Factors | 2001 |
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myristic Acid; Plasmids; Protein Binding; Recombinant Proteins | 2001 |
A randomised, controlled and blinded histological and immunohistochemical investigation of Carisolv on pulp tissue.
Topics: Animals; Calcitonin Gene-Related Peptide; Dental Cavity Preparation; Dental Pulp; Drug Evaluation, Preclinical; Glutamic Acid; Immunohistochemistry; Leucine; Lysine; Male; Neuropeptide Y; Random Allocation; Rats; Rats, Sprague-Dawley; Single-Blind Method; Substance P | 2001 |
Histocytological evaluation of the reaction of rat pulp tissue to Carisolv.
Topics: Animals; Collagen; Dental Cavity Preparation; Dental Pulp; Erythrocytes; Glutamic Acid; Leucine; Lysine; Male; Microscopy, Electron, Scanning; Necrosis; Odontoblasts; Rats; Rats, Wistar | 2001 |
Purification of anthrax edema factor from Escherichia coli and identification of residues required for binding to anthrax protective antigen.
Topics: Adenylyl Cyclases; Animals; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Escherichia coli; Exotoxins; Gene Expression; Glutamic Acid; Glycine; Isoleucine; Lysine; Receptors, Peptide; Recombinant Fusion Proteins; Tyrosine; Valine | 2001 |
Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase.
Topics: Amino Acids; Aspartic Acid; beta-Cyclodextrins; Binding Sites; Cyclodextrins; Dose-Response Relationship, Drug; Escherichia coli; Glucosyltransferases; Glutamic Acid; Histidine; Hydrolysis; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Protein Binding; Protein Conformation; Substrate Specificity; Water | 2001 |
The distal hinge of the reactive site loop and its proximity: a target to modulate plasminogen activator inhibitor-1 activity.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Arginine; Aspartic Acid; Binding Sites; DNA; Epitopes; Glutamic Acid; Histidine; Humans; Kinetics; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Plasminogen Activator Inhibitor 1; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Surface Plasmon Resonance; Swine; Time Factors | 2001 |
Site-directed mutagenesis of m1-toxin1: two amino acids responsible for stable toxin binding to M(1) muscarinic receptors.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; DNA, Complementary; Elapid Venoms; Elapidae; Glutamic Acid; Isoleucine; Lysine; Models, Molecular; Molecular Sequence Data; Muscarinic Antagonists; Mutagenesis, Site-Directed; Phenylalanine; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; Sequence Homology, Amino Acid | 2001 |
Characterization of the phosphoenolpyruvate carboxykinase gene from Corynebacterium glutamicum and significance of the enzyme for growth and amino acid production.
Topics: Amino Acid Sequence; Amino Acids; Animals; Base Sequence; Cloning, Molecular; Corynebacterium; DNA, Bacterial; Gene Expression; Genes, Bacterial; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Phosphoenolpyruvate Carboxykinase (GTP); Restriction Mapping; Sequence Homology, Amino Acid | 2001 |
Removal effects of the Nd:YAG laser and Carisolv on carious dentin.
Topics: Dental Caries; Dental Cavity Preparation; Glutamic Acid; Humans; Laser Therapy; Leucine; Lysine | 2000 |
Crystal structure at 1.5-A resolution of Pyrus pyrifolia pistil ribonuclease responsible for gametophytic self-incompatibility.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Glutamic Acid; Histidine; Lysine; Models, Molecular; Molecular Sequence Data; Plants; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Ribonucleases; Sequence Homology, Amino Acid | 2001 |
Clinical evaluation of Carisolv in the chemico-mechanical removal of carious dentin.
Topics: Child; Dental Caries; Dental Cavity Preparation; Dental Marginal Adaptation; Dental Restoration, Permanent; Dentin; Erythrosine; Fluorescent Dyes; Follow-Up Studies; Glutamic Acid; Humans; Leucine; Lysine; Molar; Oxidants; Patient Satisfaction; Radiography; Sodium Hypochlorite; Statistics, Nonparametric; Time Factors; Tooth, Deciduous | 2001 |
GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase.
Topics: Adolescent; Adult; Aged; Alleles; Amino Acid Substitution; Arginine; cis-trans-Isomerases; Female; Glutamic Acid; Glutathione Transferase; Glycine; Humans; Leucine; Lysine; Male; Methionine; Middle Aged; Proline; Threonine | 2001 |
Characterization and biological activities of Chenopodium leaf hemagglutinin (CLH).
Topics: Amino Acids; Animals; Aspartic Acid; Cell Aggregation; Chenopodium; Dose-Response Relationship, Drug; Erythrocytes; Glutamic Acid; Glycine; Hemagglutinins; Lysine; Methionine; Mice; Phenylalanine; Plant Leaves; Rabbits; Rats; Spleen; Thymus Gland; Tryptophan | 2001 |
Tcf4 can specifically recognize beta-catenin using alternative conformations.
Topics: Amino Acid Sequence; Animals; beta Catenin; Binding Sites; Crystallography, X-Ray; Cytoskeletal Proteins; Glutamic Acid; HMGB Proteins; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Precipitin Tests; Protein Binding; Protein Conformation; Protein Interaction Mapping; Repetitive Sequences, Amino Acid; Static Electricity; Substrate Specificity; TCF Transcription Factors; Trans-Activators; Transcription Factor 7-Like 1 Protein; Transcription Factor 7-Like 2 Protein; Transcription Factors; Xenopus Proteins | 2001 |
Identification and characterization of an output neuron from the oscillatory molluscan olfactory network.
Topics: Animals; Biological Clocks; Carbocyanines; Central Nervous System; Electric Stimulation; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Ganglia, Invertebrate; Glutamic Acid; Lysine; Membrane Potentials; Mollusca; Neurites; Neurons; Olfactory Pathways; Presynaptic Terminals; Reaction Time; Smell; Synaptic Transmission | 2001 |
Reaction of sound and demineralised dentine to Carisolv in vivo and in vitro.
Topics: Animals; Dental Pulp; Dentin; Edetic Acid; Fibrillar Collagens; Glutamic Acid; Leucine; Lysine; Male; Microscopy, Electron, Scanning; Odontoblasts; Rats; Rats, Wistar; Tooth Demineralization | 2002 |
Molecular determinants of high affinity binding to group III metabotropic glutamate receptors.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Immunoblotting; Immunohistochemistry; Ligands; Lysine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Receptors, Metabotropic Glutamate; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2002 |
New MCAD gene mutation, not previously reported in other nations, found at A1161G in Turkish population.
Topics: Acyl-CoA Dehydrogenase; Amino Acid Substitution; Chromosome Mapping; Chromosomes, Human, Pair 1; Fatty Acid Desaturases; Female; Gene Frequency; Glutamic Acid; Humans; Infant, Newborn; Lysine; Mothers; Mutation; Turkey | 2001 |
Specificity determining residues in ammonia- and glutamine-dependent carbamoyl phosphate synthetases.
Topics: Adenosine Triphosphate; Allosteric Site; Amino Acid Sequence; Ammonia; Animals; Binding Sites; Blotting, Western; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cysteine; Escherichia coli; Glutamic Acid; Glutamine; Humans; Kinetics; Leucine; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Protein Binding; Protein Structure, Tertiary; Ranidae; Rats; Recombinant Proteins; Substrate Specificity | 2002 |
Chiral amplification of oligopeptides in two-dimensional crystalline self-assemblies on water.
Topics: Biopolymers; Crystallization; Glutamic Acid; Lysine; Oligopeptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Water; X-Ray Diffraction | 2002 |
An optimized solid phase synthesis strategy--including on-resin lactamization--of astressin, its retro-, inverso-, and retro-inverso isomers as corticotropin releasing factor antagonists.
Topics: Amino Acid Sequence; Animals; beta-Galactosidase; Cells, Cultured; Circular Dichroism; Corticotropin-Releasing Hormone; Genes, Reporter; Glutamic Acid; Humans; Lactams; Lysine; Mice; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Conformation; Protein Structure, Secondary; Receptors, Corticotropin-Releasing Hormone; Resins, Plant; Stereoisomerism; Water | 2002 |
Reactions in the oral mucous membrane after exposure to Carisolv--combined results from a clinical screening test in humans and an experimental study in rats.
Topics: Adult; Animals; Dental Cavity Preparation; Female; Gingivitis; Glutamic Acid; Humans; Leucine; Lingual Frenum; Lysine; Male; Mouth Mucosa; Rats; Rats, Sprague-Dawley | 2001 |
Determination of residual dentine caries after conventional mechanical and chemomechanical caries removal with Carisolv.
Topics: Azo Compounds; Coloring Agents; Dental Caries; Dental Caries Activity Tests; Dental Cavity Preparation; Dentin; Glutamic Acid; Hardness; Humans; Hydrogen-Ion Concentration; Leucine; Lysine; Microscopy, Electron, Scanning; Microscopy, Video; Plastic Embedding; Smear Layer; Sound; Statistics as Topic | 2001 |
The function of Asp70, Glu77 and Lys79 in the Escherichia coli MutH protein.
Topics: Adenosine Triphosphatases; Amino Acid Substitution; Aspartic Acid; Bacterial Proteins; Base Sequence; Binding Sites; Catalysis; DNA; DNA Repair Enzymes; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Genetic Complementation Test; Glutamic Acid; Lysine; Models, Molecular; Mutation; MutL Proteins; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Structure-Activity Relationship; Thermodynamics | 2002 |
Three subunits contribute amino acids to the active site of tetrameric adenylosuccinate lyase: Lys268 and Glu275 are required.
Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Alanine; Amino Acid Substitution; Arginine; Bacillus subtilis; Binding Sites; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Genetic Complementation Test; Glutamic Acid; Kinetics; Light; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Peptide Fragments; Protein Structure, Secondary; Scattering, Radiation; Tritium | 2002 |
Decreased expression of the GHRH receptor gene due to a mutation in a Pit-1 binding site.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; Child, Preschool; CHO Cells; Cricetinae; Cyclic AMP; DNA Mutational Analysis; DNA-Binding Proteins; Gene Expression; Glutamic Acid; Growth Hormone-Releasing Hormone; Heterozygote; Human Growth Hormone; Humans; Luciferases; Lysine; Male; Mutation; Mutation, Missense; Pituitary Gland; Promoter Regions, Genetic; Rats; Receptors, Neuropeptide; Receptors, Pituitary Hormone-Regulating Hormone; Transcription Factor Pit-1; Transcription Factors; Transfection | 2002 |
Tn5 transposase active site mutants.
Topics: Arginine; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; DNA, Bacterial; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Conformation; Transposases; Tyrosine | 2002 |
The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA.
Topics: Amino Acid Substitution; Animals; Base Sequence; Binding Sites, Antibody; Cell Line; Chromatin; DNA-Binding Proteins; Gene Silencing; Glutamic Acid; Glutamine; Humans; Immunoglobulin A; Immunoglobulin alpha-Chains; Immunoglobulin Class Switching; Immunoglobulin mu-Chains; Immunoglobulin Switch Region; Leucine; Lymphoma, B-Cell; Lysine; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Repressor Proteins; RNA-Binding Proteins; Spleen; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Chemiluminometric sensor for simultaneous determination of L-glutamate and L-lysine with immobilized oxidases in a flow injection system.
Topics: Artifacts; Biosensing Techniques; Enzymes, Immobilized; Flow Injection Analysis; Glutamic Acid; Luminescent Measurements; Lysine; Oxidoreductases; Reproducibility of Results; Uric Acid | 2002 |
Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.
Topics: Amino Acid Substitution; Animals; Chorionic Gonadotropin; COS Cells; Cyclic AMP; Flow Cytometry; Glutamic Acid; Humans; Hyperthyroidism; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Receptors, Thyrotropin; Structure-Activity Relationship; Thyrotropin; Transfection | 2002 |
Plasma lysine concentration and availability of 2-ketoglutarate in liver mitochondria.
Topics: Alanine; Biological Availability; Glutamic Acid; Glutamine; Humans; Infant; Ketoglutaric Acids; Lysine; Mitochondria, Liver | 2002 |
Glu274Lys/Gly309Arg mutation of the tissue-nonspecific alkaline phosphatase gene in neonatal hypophosphatasia associated with convulsions.
Topics: Alkaline Phosphatase; Arginine; Female; Glutamic Acid; Humans; Hypophosphatasia; Infant, Newborn; Lysine; Mutation, Missense; Seizures | 2002 |
Experimental pK(a) values of buried residues: analysis with continuum methods and role of water penetration.
Topics: Binding Sites; Biophysical Phenomena; Biophysics; Crystallography, X-Ray; Electrochemistry; Glutamic Acid; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lysine; Micrococcal Nuclease; Models, Molecular; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protons; Thermodynamics; Water | 2002 |
Redox-coupled proton pumping activity in cytochrome b6f, as evidenced by the pH dependence of electron transfer in whole cells of Chlamydomonas reinhardtii.
Topics: Animals; Catalysis; Chlamydomonas reinhardtii; Cytochrome b Group; Cytochrome b6f Complex; Electron Transport; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Oxidation-Reduction; Plastoquinone; Proton Pumps; Protons | 2002 |
Molecular characterization of an extended binding site for coagulation factor Va in the positive exosite of activated protein C.
Topics: Alanine; Arginine; Binding Sites; DNA Mutational Analysis; Factor Va; Fibrinolytic Agents; Glutamic Acid; Humans; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein C; Recombinant Proteins; Time Factors | 2002 |
A case of hyperlipidemia with homozygous apolipoprotein E5 (Glu3-->Lys).
Topics: Adult; Amino Acid Substitution; Apolipoproteins E; Base Sequence; DNA Primers; Electrophoresis, Agar Gel; Female; Genotype; Glutamic Acid; Humans; Hyperlipidemias; Lipoprotein Lipase; Lysine; Male; Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length | 2002 |
Flavor release in the presence of melanoidins prepared from L-(+)-ascorbic acid and amino acids.
Topics: Amino Acids; Ascorbic Acid; Dialysis; Glucose; Glutamic Acid; Glycine; Lysine; Molecular Weight; Pentanols; Polymers; Solubility | 2002 |
Lys 43 and Asp 46 in alpha-helix 3 of uteroglobin are essential for its phospholipase A2 inhibitory activity.
Topics: Aspartic Acid; Calcium; Chromatography, Thin Layer; Dimerization; DNA, Complementary; Dose-Response Relationship, Drug; Glutamic Acid; Lysine; Mutagenesis, Site-Directed; Mutation; Phospholipases A; Phospholipases A2; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Uteroglobin | 2002 |
Morphological study of demineralized dentine after caries removal using two different methods.
Topics: Acid Etching, Dental; Acrylic Resins; Aluminum Chloride; Aluminum Compounds; Astringents; Chlorides; Collagen; Coloring Agents; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Phosphoric Acids; Porosity; Smear Layer | 2002 |
The influence of a chemo-mechanical caries removal solution on the topography of dental ceramic materials.
Topics: Dental Caries; Dental Cavity Preparation; Dental Materials; Dental Porcelain; Enamel Microabrasion; Equipment Design; Glutamic Acid; Hydrogen-Ion Concentration; Leucine; Lysine; Materials Testing; Metal Ceramic Alloys; Microscopy, Atomic Force; Microscopy, Confocal; Sodium Hypochlorite; Time Factors; Titanium | 2002 |
Redox-dependent structural changes in the superoxide reductase from Desulfoarculus baarsii and Treponema pallidum: a FTIR study.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Desulfovibrio; Electrochemistry; Ferredoxins; Glutamic Acid; Iron; Isoleucine; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Solutions; Spectroscopy, Fourier Transform Infrared; Treponema pallidum | 2002 |
Early sequential formation of functional GABA(A) and glutamatergic synapses on CA1 interneurons of the rat foetal hippocampus.
Topics: Animals; Cell Differentiation; Cell Size; Dendrites; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Fetus; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Immunohistochemistry; Interneurons; Lysine; Neural Pathways; Patch-Clamp Techniques; Pregnancy; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Synapses | 2002 |
A unique glutamic acid-lysine (EK) domain acts as a splicing inhibitor.
Topics: Amino Acid Sequence; Arginine; Carrier Proteins; Cell Nucleus; Codon; Exons; Glutamic Acid; HeLa Cells; Humans; Lysine; Molecular Sequence Data; Nuclear Proteins; Peptides; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA Splicing; RNA-Binding Proteins; Sequence Homology, Amino Acid; Serine; Serine-Arginine Splicing Factors; Spliceosomes; Time Factors; Transcription, Genetic; Transfection | 2002 |
Compound heterozygosity for Hb Korle-Bu (beta(73); Asp-Asn) and Hb E (beta(26); Glu-Lys) with a 3.7-kb deletional alpha-thalassemia in Thai patients.
Topics: Adolescent; Adult; Aged; alpha-Thalassemia; Asparagine; Aspartic Acid; Base Sequence; Chromosome Segregation; Female; Gene Deletion; Glutamic Acid; Hemoglobin E; Hemoglobins, Abnormal; Heterozygote; Humans; Lysine; Male; Middle Aged; Pregnancy; Thailand | 2002 |
Electrostatic contributions to site specific DNA cleavage by EcoRV endonuclease.
Topics: Alanine; Aspartic Acid; Binding Sites; Catalysis; Cations, Divalent; Crystallography, X-Ray; Deoxyribonucleases, Type II Site-Specific; DNA, Bacterial; Glutamic Acid; Kinetics; Lysine; Manganese; Mutagenesis, Site-Directed; Static Electricity | 2002 |
The entry point of the K-proton-transfer pathway in cytochrome c oxidase.
Topics: Carbon Monoxide; Conserved Sequence; Electron Transport; Electron Transport Complex IV; Glutamic Acid; Lysine; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Photolysis; Protein Subunits; Protons; Rhodobacter sphaeroides; Serine | 2002 |
Mutational, kinetic, and NMR studies of the mechanism of E. coli GDP-mannose mannosyl hydrolase, an unusual Nudix enzyme.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Catalysis; DNA Mutational Analysis; Escherichia coli Proteins; Glutamic Acid; Glutamine; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nudix Hydrolases; Osmolar Concentration; Protons; Pyrophosphatases; Temperature | 2002 |
The prevalent Glu23Lys polymorphism in the potassium inward rectifier 6.2 (KIR6.2) gene is associated with impaired glucagon suppression in response to hyperglycemia.
Topics: Adult; Alleles; Female; Gene Frequency; Glucagon; Glutamic Acid; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Lysine; Male; Polymorphism, Genetic; Potassium Channels, Inwardly Rectifying | 2002 |
Two highly conserved glutamate residues critical for type III sodium-dependent phosphate transport revealed by uncoupling transport function from retroviral receptor function.
Topics: Amino Acid Substitution; Animals; Biotinylation; Cell Line; Conserved Sequence; Glutamic Acid; Glutamine; Humans; Lysine; Mutagenesis, Site-Directed; Oocytes; Phosphates; Protein Folding; Receptors, Virus; Recombinant Proteins; Retroviridae; Saccharomyces cerevisiae Proteins; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type III; Symporters; Transfection; Xenopus laevis | 2002 |
Site-directed mutagenesis of conserved charged amino acid residues in ClpB from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Acidic; Amino Acids, Basic; Arginine; Conserved Sequence; Endopeptidase Clp; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Threonine | 2002 |
Mapping the type I collagen-binding site on pigment epithelium-derived factor. Implications for its antiangiogenic activity.
Topics: Animals; Aspartic Acid; Binding Sites; Cattle; Cell Line; Collagen Type I; Cornea; Cricetinae; Eye Proteins; Fluorescein; Glutamic Acid; Heparin; Humans; Lysine; Models, Molecular; Nerve Growth Factors; Peptides; Polyelectrolytes; Polymers; Protein Binding; Protein Structure, Tertiary; Proteins; Radioligand Assay; Recombinant Proteins; Serpins; Vitreous Body | 2002 |
The Glu-84 of the ParC subunit plays critical roles in both topoisomerase IV-quinolone and topoisomerase IV-DNA interactions.
Topics: 4-Quinolones; Anti-Infective Agents; Calcium; Catalysis; Catalytic Domain; DNA Damage; DNA Topoisomerase IV; DNA, Bacterial; Drug Resistance, Bacterial; Enzyme Stability; Glutamic Acid; Leucine; Lysine; Macromolecular Substances; Magnesium; Mutagenesis, Site-Directed; Protein Subunits; Serine; Substrate Specificity | 2002 |
Synthesis and biodegradation of arabinogalactan sponges prepared by reductive amination.
Topics: Animals; Biocompatible Materials; Carbohydrate Sequence; Chitin; Chitosan; Female; Galactans; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Molecular Sequence Data; Molecular Weight; Polysaccharides; Polysaccharides, Bacterial; Temperature; Time Factors; Tissue Engineering | 2002 |
New intrathalamic pathways allowing modality-related and cross-modality switching in the dorsal thalamus.
Topics: Action Potentials; Animals; Attention; Glutamic Acid; In Vitro Techniques; Lysine; Nerve Net; Neural Inhibition; Neural Pathways; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Stimulation, Chemical; Synaptic Transmission; Thalamic Nuclei; Thalamus | 2002 |
Contribution of Lys276 to the conformational flexibility of the active site of glutamate decarboxylase from Escherichia coli.
Topics: Binding Sites; Circular Dichroism; Escherichia coli Proteins; Glutamate Decarboxylase; Glutamic Acid; Lysine; Mutation; Protein Conformation; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry | 2002 |
Effect of a new injectable male contraceptive on the seminal plasma amino acids studied by proton NMR spectroscopy.
Topics: Adult; Alanine; Amino Acids; Arginine; Contraceptive Agents, Male; Dimethyl Sulfoxide; Glutamic Acid; Glutamine; Humans; Injections; Isoleucine; Leucine; Lysine; Magnetic Resonance Spectroscopy; Male; Maleates; Polyesters; Polystyrenes; Semen; Styrenes; Valine; Vas Deferens | 2002 |
Characterization of large peptide fragments derived from the N-terminal domain of the ribosomal protein L9: definition of the minimum folding motif and characterization of local electrostatic interactions.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Molecular Sequence Data; Naphthalenesulfonates; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Ribosomal Proteins; Spectrometry, Fluorescence; Static Electricity | 2002 |
Location of the pteroylpolyglutamate-binding site on rabbit cytosolic serine hydroxymethyltransferase.
Topics: Animals; Binding Sites; Cations; Crystallography, X-Ray; Cytosol; Glutamic Acid; Glutamine; Glycine Hydroxymethyltransferase; Kinetics; Ligands; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Pteroylpolyglutamic Acids; Rabbits | 2003 |
Valine 114 replacements in archaeal elongation factor 1 alpha enhanced its ability to interact with aminoacyl-tRNA and kirromycin.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Glutamic Acid; GTP Phosphohydrolases; Hot Temperature; Lysine; Mutagenesis, Site-Directed; Peptide Elongation Factor 1; Protein Denaturation; Pyridones; RNA, Transfer, Amino Acid-Specific; Structure-Activity Relationship; Sulfolobus; Valine | 2002 |
Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase: theoretical and experimental study of the effect of glutamic acid 284 on the protonation state of lysine 213.
Topics: Amino Acid Sequence; Conserved Sequence; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Phosphoenolpyruvate Carboxykinase (ATP); Protein Structure, Tertiary; Protons; Saccharomyces cerevisiae | 2002 |
Conformational changes in hemoglobin S (betaE6V) imposed by mutation of the beta Glu7-beta Lys132 salt bridge and detected by UV resonance Raman spectroscopy.
Topics: Dimerization; Glutamic Acid; Hemoglobin, Sickle; Humans; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Mutation; Point Mutation; Protein Conformation; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Ultraviolet Rays | 2003 |
Neurons of the superior olivary complex do not excite startle-mediating neurons in the caudal pontine reticular formation.
Topics: Animals; Auditory Pathways; Cochlear Nucleus; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamates; Glutamic Acid; Immunohistochemistry; Lysine; Olivary Nucleus; Photic Stimulation; Photochemistry; Pons; Rats; Reflex, Startle; Reticular Formation; Synaptic Transmission; Ultraviolet Rays | 2002 |
Molecular studies of the synergistic interactions between plum pox virus HC-Pro protein and potato virus X.
Topics: Amino Acid Substitution; Cysteine Endopeptidases; Genetic Vectors; Glutamic Acid; Lysine; Mutation; Nicotiana; Plant Diseases; Plum Pox Virus; Potexvirus; Protein Binding; Reassortant Viruses; Viral Proteins; Virulence | 2002 |
Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography.
Topics: Amino Acid Sequence; Animals; Catalysis; Cell Survival; Circular Dichroism; Crystallography, X-Ray; DNA, Complementary; Genetic Vectors; Glutamic Acid; Guanine; Humans; Hydrogen; Kinetics; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Protein Structure, Tertiary; Rana catesbeiana; Recombinant Proteins; Ribonuclease, Pancreatic; Ribonucleases; RNA; Sequence Homology, Amino Acid; Substrate Specificity; Threonine | 2003 |
Structural and thermodynamic studies on a salt-bridge triad in the NADP-binding domain of glutamate dehydrogenase from Thermotoga maritima: cooperativity and electrostatic contribution to stability.
Topics: Alanine; Arginine; Binding Sites; Crystallography, X-Ray; Cysteine; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Guanidine; Lysine; Mutagenesis, Site-Directed; NADP; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Salts; Serine; Static Electricity; Structure-Activity Relationship; Thermodynamics; Thermotoga maritima; Urea | 2002 |
A new method to estimate the relative bioavailability of individual amino acids in fish larvae using 13C-NMR spectroscopy.
Topics: Amino Acids; Animals; Aspartic Acid; Carbon; Chromatography, High Pressure Liquid; Glutamic Acid; Lysine; Magnetic Resonance Spectroscopy; Sea Bream | 2003 |
Charge-charge interactions are key determinants of the pK values of ionizable groups in ribonuclease Sa (pI=3.5) and a basic variant (pI=10.2).
Topics: Aspartic Acid; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Isoelectric Point; Isoenzymes; Lysine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Ribonucleases; Tyrosine | 2003 |
Expression of an artificial polypeptide with a repeated tripeptide glutamyl-tryptophanyl-lysine in Saccharomyces cerevisiae.
Topics: Amino Acids, Essential; Cloning, Molecular; Culture Media; Electrophoresis, Polyacrylamide Gel; Genes, Synthetic; Glutamic Acid; Lysine; Models, Genetic; Oligopeptides; Plasmids; Recombinant Proteins; Repetitive Sequences, Amino Acid; Saccharomyces cerevisiae; Tryptophan | 2003 |
Changes in stability upon charge reversal and neutralization substitution in staphylococcal nuclease are dominated by favorable electrostatic effects.
Topics: Amino Acid Substitution; Aspartic Acid; Enzyme Stability; Glutamic Acid; Glutamine; Guanidine; Histidine; Hydrogen-Ion Concentration; Lysine; Micrococcal Nuclease; Models, Chemical; Normal Distribution; Poisson Distribution; Protein Denaturation; Protein Folding; Static Electricity; Surface Properties; Thermodynamics | 2003 |
Dopamine enhances EPSCs in layer II-III pyramidal neurons in rat prefrontal cortex.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Agonists; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; In Vitro Techniques; Lysine; Patch-Clamp Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2003 |
Functional evidence for an intramolecular side chain interaction between residues 6 and 10 of receptor-bound parathyroid hormone analogues.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cattle; Cyclic AMP; Glutamic Acid; Humans; Lactams; LLC-PK1 Cells; Lysine; Molecular Sequence Data; Opossums; Parathyroid Hormone; Peptide Fragments; Protein Binding; Protein Structure, Secondary; Rats; Receptors, Parathyroid Hormone; Swine | 2003 |
Ruthenium red inhibits TASK-3 potassium channel by interconnecting glutamate 70 of the two subunits.
Topics: Animals; Arginine; Coloring Agents; Cysteine; Dimerization; Glutamic Acid; Humans; Lysine; Mice; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Potassium Channels; Potassium Channels, Tandem Pore Domain; Ruthenium Red | 2003 |
NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Genetic Variation; Glutamic Acid; Glycine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Ovomucin; Protein Conformation; Protein Structure, Tertiary; Serine Proteinase Inhibitors; Thermodynamics; Threonine; Titrimetry; Turkeys | 2003 |
Mutants of phosphorylase a altered in recognition by protein phosphatase-1.
Topics: Amino Acid Substitution; Arginine; Glutamic Acid; Glycine; Isoleucine; Kinetics; Lysine; Mutagenesis, Site-Directed; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylase a; Phosphorylase b; Phosphorylation; Protein Phosphatase 1; Substrate Specificity | 2003 |
Recurrent missense mutations in the hair keratin gene hHb6 in monilethrix.
Topics: Colombia; DNA Mutational Analysis; Female; Glutamic Acid; Hair Diseases; Humans; Keratins; Lysine; Male; Mutation, Missense; Pedigree; Russia | 2003 |
Increased lysine synthesis coupled with a knockout of its catabolism synergistically boosts lysine content and also transregulates the metabolism of other amino acids in Arabidopsis seeds.
Topics: Amino Acids; Arabidopsis; Asparagine; Aspartic Acid; Bacteria; Bacterial Proteins; Gene Expression Regulation, Plant; Germination; Glutamic Acid; Glutamine; Hydro-Lyases; Lysine; Methionine; Mutation; Plants, Genetically Modified; Pterocarpans; Seeds; Signal Transduction; Threonine | 2003 |
Gonadotropin releasing hormone (GnRH) modulates odorant responses in the peripheral olfactory system of axolotls.
Topics: Ambystoma mexicanum; Animals; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Lysine; Male; Methionine; Odorants; Olfactory Mucosa; Olfactory Receptor Neurons | 2003 |
Distinctive cerebellar immunoreactivity for the prion protein in familial (E200K) Creutzfeldt-Jakob disease.
Topics: Cerebellum; Creutzfeldt-Jakob Syndrome; Genetic Variation; Glutamic Acid; Humans; Immunohistochemistry; Lysine; Methionine; Mutation; Prions; Valine | 2003 |
Homochiral oligopeptides by chiral amplification within two-dimensional crystalline self-assemblies at the air-water interface; relevance to biomolecular handedness.
Topics: Air; Crystallization; Deuterium; Glutamic Acid; Lysine; Models, Molecular; Oligopeptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Surface Properties; Water; X-Ray Diffraction | 2003 |
Plasma amino acid levels in children with autism and their families.
Topics: Adolescent; Alanine; Amino Acids; Asparagine; Asperger Syndrome; Autistic Disorder; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Family; Female; Glutamic Acid; Glutamine; Humans; Lysine; Male; Phenylalanine; Tyrosine | 2003 |
Mutational analysis of Lys252 and its interaction with loop 6-7 in the SR Ca2+-ATPase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Calcium-Transporting ATPases; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2003 |
Dependence of mu-conotoxin block of sodium channels on ionic strength but not on the permeating [Na+]: implications for the distinctive mechanistic interactions between Na+ and K+ channel pore-blocking toxins and their molecular targets.
Topics: Animals; Arginine; Calcium Channel Blockers; Conotoxins; Glutamic Acid; Ion Channel Gating; Lysine; Membrane Potentials; Muscle, Skeletal; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Rats; Sodium; Sodium Channel Blockers; Sodium Channels | 2003 |
The mutation of Hb Turriff [alpha99(G6)Lys --> Glu (AAG --> GAG)] is carried by the alpha1-globin gene in a Japanese (Hb Turriff-I).
Topics: Aged; Base Sequence; DNA Primers; Female; Globins; Glutamic Acid; Hemoglobins, Abnormal; Humans; Japan; Lysine; Male; Mutation, Missense | 2003 |
NMR studies of the fifth transmembrane segment of sarcoplasmic reticulum Ca2+-ATPase reveals a hinge close to the Ca2+-ligating residues.
Topics: Amino Acid Sequence; Binding Sites; Calcium; Calcium-Transporting ATPases; Crystallography, X-Ray; Cytoplasm; Glutamic Acid; Intracellular Membranes; Lipid Bilayers; Lysine; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Molecular Sequence Data; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Sarcoplasmic Reticulum; Sodium Dodecyl Sulfate | 2003 |
pH-triggered strand exchange in coiled-coil heterotrimers.
Topics: Amino Acid Sequence; Cross-Linking Reagents; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Proteins | 2003 |
Identification of the catalytic residues of AroA (Enolpyruvylshikimate 3-phosphate synthase) using partitioning analysis.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Substitution; Binding Sites; Carbon Isotopes; Catalysis; Computer Simulation; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Numerical Analysis, Computer-Assisted; Phosphoenolpyruvate; Recombinant Proteins; Shikimic Acid | 2003 |
Preliminary in vitro evaluation of Carisolv as a root canal irrigant.
Topics: Animals; Dental Pulp Cavity; Disinfectants; Drug Evaluation, Preclinical; Glutamic Acid; Leucine; Lysine; Microscopy, Electron, Scanning; Observer Variation; Pulpectomy; Reproducibility of Results; Root Canal Irrigants; Sheep; Sodium Chloride; Sodium Hypochlorite; Statistics, Nonparametric; Tooth Apex; Ultrasonics | 2003 |
Malleable conformation of the elastic PEVK segment of titin: non-co-operative interconversion of polyproline II helix, beta-turn and unordered structures.
Topics: Amino Acid Motifs; Amino Acid Sequence; Circular Dichroism; Connectin; Elasticity; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Muscle Proteins; Nuclear Magnetic Resonance, Biomolecular; Osmolar Concentration; Peptides; Proline; Protein Conformation; Protein Kinases; Protein Structure, Secondary; Protein Structure, Tertiary; Salts; Stereoisomerism; Trifluoroethanol; Urea; Valine | 2003 |
Disease-related metabolites in culture medium of fibroblasts from patients with D-2-hydroxyglutaric aciduria, L-2-hydroxyglutaric aciduria, and combined D/L-2-hydroxyglutaric aciduria.
Topics: Biomarkers; Cell Line; Culture Media; Fibroblasts; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Glutarates; Humans; Ketoglutaric Acids; Lysine; Metabolic Diseases; Stereoisomerism; Succinic Acid | 2003 |
Glutamatergic input governs periodicity and synchronization of bursting activity in oxytocin neurons in hypothalamic organotypic cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anesthetics, Inhalation; Animals; Animals, Newborn; Bicuculline; Biotin; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Halothane; Hypothalamus; Lysine; Neurons; Neurophysins; Organ Culture Techniques; Oxytocin; Periodicity; Propionates; Rats; Rats, Wistar; Vasopressins | 2003 |
Unique stabilizing interactions identified in the two-stranded alpha-helical coiled-coil: crystal structure of a cortexillin I/GCN4 hybrid coiled-coil peptide.
Topics: Amino Acid Sequence; Circular Dichroism; Crystallography, X-Ray; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Leucine; Lysine; Microfilament Proteins; Models, Molecular; Molecular Sequence Data; Oligopeptides; Peptides; Protein Structure, Secondary; Protozoan Proteins | 2003 |
A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Carnitine; Carnitine O-Palmitoyltransferase; Chickens; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Humans; Immunoblotting; Kinetics; Liver; Lysine; Malonyl Coenzyme A; Mice; Molecular Sequence Data; Muscles; Mutation; Palmitoyl Coenzyme A; Pichia; Polymerase Chain Reaction; Protein Isoforms; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Swine | 2003 |
Role of the Bacillus methanolicus citrate synthase II gene, citY, in regulating the secretion of glutamate in L-lysine-secreting mutants.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; Bioreactors; Biotechnology; Citrate (si)-Synthase; Cloning, Molecular; Culture Media; Gene Expression Regulation, Bacterial; Glutamic Acid; Lysine; Methanol; Molecular Sequence Data; Mutation; Sequence Alignment; Sequence Analysis, DNA | 2003 |
Electrostatic interactions in leucine zippers: thermodynamic analysis of the contributions of Glu and His residues and the effect of mutating salt bridges.
Topics: Amino Acid Sequence; Arginine; DNA-Binding Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Leucine Zippers; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Norleucine; Peptides; Protein Folding; Protein Kinases; Saccharomyces cerevisiae Proteins; Salts; Static Electricity; Thermodynamics | 2003 |
Deletions of any single residues in Glu40-Ser48 loop connecting a domain and the first transmembrane helix of sarcoplasmic reticulum Ca(2+)-ATPase result in almost complete inhibition of conformational transition and hydrolysis of phosphoenzyme intermedia
Topics: Adenosine Triphosphate; Animals; Asparagine; Calcium-Transporting ATPases; COS Cells; Enzyme Activation; Gene Deletion; Glutamic Acid; Hydrogen Bonding; Hydrolysis; Lysine; Microsomes; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Rabbits; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2003 |
Fulfenamic acid sensitive, Ca(2+)-dependent inward current induced by nicotinic acetylcholine receptors in dopamine neurons.
Topics: Acetates; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Atropine; Calcium; Carbachol; Chelating Agents; Chlorides; Cholinergic Agonists; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Conductivity; Flufenamic Acid; Glutamic Acid; In Vitro Techniques; Lactones; Lysine; Mecamylamine; Membrane Potentials; Muscarinic Antagonists; Neurons; Nicotinic Antagonists; Patch-Clamp Techniques; Phenytoin; Rats; Rats, Wistar; Receptors, Nicotinic; Sesquiterpenes; Substantia Nigra; Ventral Tegmental Area | 2003 |
Surface salt bridges modulate DNA wrapping by the type II DNA-binding protein TF1.
Topics: Alanine; Anions; Aspartic Acid; Bacillus subtilis; Bacteriophages; Cations; Cross-Linking Reagents; Dimerization; DNA; DNA-Binding Proteins; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Glutaral; Ions; Kinetics; Lysine; Models, Molecular; Mutation; Pentoxyl; Plasmids; Protein Binding; Salts; Thermotoga maritima; Thymine; Viral Proteins | 2003 |
Mutation of a dibasic amino acid motif within the C terminus of the P2X7 nucleotide receptor results in trafficking defects and impaired function.
Topics: Amino Acid Motifs; Amino Acids, Diamino; Arginine; Cell Line; Cell Membrane; Glutamic Acid; Humans; Ion Channels; Lysine; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Peptide Fragments; Point Mutation; Protein Structure, Tertiary; Protein Transport; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Temperature | 2003 |
A morphological and micro-tensile bond strength evaluation of a single-bottle adhesive to caries-affected human dentine after four different caries removal techniques.
Topics: Air Abrasion, Dental; Bisphenol A-Glycidyl Methacrylate; Composite Resins; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dentin; Dentin Permeability; Dentin-Bonding Agents; Fluorescence; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Microscopy, Electron, Scanning; Molar; Tensile Strength; Ultrasonic Therapy | 2003 |
Determinants of binding affinity and specificity for the interaction of TEM-1 and SME-1 beta-lactamase with beta-lactamase inhibitory protein.
Topics: Alanine; Bacterial Proteins; beta-Lactamases; Binding Sites; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epitopes; Escherichia coli; Glutamic Acid; Hydrolysis; Kinetics; Lysine; Models, Molecular; Mutagenesis; Mutation; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Conformation; Protein Structure, Tertiary | 2003 |
Effects of chloramines and sodium hypochlorite on carious dentin.
Topics: Cariostatic Agents; Chloramines; Dental Caries; Dental Cavity Preparation; Dentin; Drug Interactions; Glutamic Acid; Hardness; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Sodium Hypochlorite | 2003 |
Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site.
Topics: Animals; Binding Sites; Birds; Carbon; Crystallography, X-Ray; Dimerization; Drug Design; Escherichia coli; Folic Acid; Glutamic Acid; Hydroxymethyl and Formyl Transferases; Kinetics; Lysine; Models, Chemical; Models, Molecular; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Purines; Ribonucleotides; Tetrahydrofolates; Water | 2003 |
The assimilation of amino-acids by micro-organisms. XVI. Changes in sodium and potassium accompanying the accumulation of glutamic acid or lysine by bacteria and yeast.
Topics: Amino Acids; Bacteria; Glutamates; Glutamic Acid; Lysine; Micrococcus; Potassium; Saccharomyces cerevisiae; Sodium; Streptococcus; Yeasts | 1953 |
The metabolic conversion of the carbon chain of lysine-6-C14 to glutamic acid, aspartic acid and arginine.
Topics: Arginine; Aspartic Acid; Biochemical Phenomena; Carbon; Glutamates; Glutamic Acid; Lysine | 1954 |
Use of enzymes and radiocarbon in estimation of the equilibrium constants for the decarboxylation of lysine and glutamate.
Topics: Decarboxylation; Glutamates; Glutamic Acid; Lyases; Lysine | 1958 |
Metabolic characterization of the genus Brucella. I. Statistical evaluation of the oxidative rates by which type I of each species can be identified.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Asparagine; Brucella; Brucella abortus; Brucella melitensis; Brucella suis; Brucellosis; Carbohydrate Metabolism; Galactose; Glutamic Acid; Lysine; Ornithine; Oxidation-Reduction; Ribose; Xylose | 1961 |
Metabolic characterization of the genus Brucella. II. Oxidative metabolic patterns of the described biotypes.
Topics: Amino Acids; Arginine; Brucella; Brucella abortus; Brucella suis; Carbohydrate Metabolism; Carbohydrates; Cell Respiration; Glutamic Acid; Lysine; Oxidation-Reduction | 1961 |
Nutrition of five Bacteroides strains.
Topics: Amino Acids; Arginine; Bacteroides; Culture Media; Fusobacterium; Glucose; Glutamic Acid; Histidine; Lysine; Phenylalanine; Purines; Tyrosine; Vitamins | 1962 |
Studies on artifical antigens. I. Antigenicity of DNP-polylysine and DNP copolymer of lysine and glutamic acid in guinea pigs.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Antigens; Dinitrobenzenes; Dinitrophenols; Glutamic Acid; Glutaminase; Guinea Pigs; Lysine; Nitrophenols; Polylysine | 1963 |
EFFECT OF TETRACYCLINES ON THE INTRACELLULAR AMINO ACIDS OF MOLDS.
Topics: Alanine; Amino Acids; Arginine; Fungi; Glutamic Acid; Lysine; Phenylalanine; Proline; Tetracycline; Tetracyclines; Tyrosine | 1963 |
EFFECT OF CATIONS UPON HYDROPHOBICITY OF YEASTS GROWN IN AMINO ACID MEDIA.
Topics: Amino Acids; Ammonium Compounds; Cations; Chlorides; Culture Media; Glutamic Acid; Histidine; Hydrophobic and Hydrophilic Interactions; Lysine; Nitrogen; Phenylalanine; Proline; Quaternary Ammonium Compounds; Research; Tryptophan; Tyrosine; Valine; Yeasts | 1963 |
ANTIGENICITY OF POLYPEPTIDES (POLY ALPHA AMINO ACIDS). XII. IMMUNOLOGICAL STUDIES WITH A NEW GROUP OF SYNTHETIC COPOLYMERS.
Topics: Alanine; Animals; Antibody Formation; Antigens; Glutamates; Glutamic Acid; Guinea Pigs; Immunoelectrophoresis; Lysine; Peptides; Polymers; Precipitin Tests; Rabbits; Research; Tyrosine; Valine | 1964 |
THE SYNTHESIS OF 1-LYSINE, 1-ORNITHINE, 1-CITRULLINE, 1-GLUTAMIC ACID, AND 1-DESARGININE BRADYKININ.
Topics: Blood Pressure; Bradykinin; Bronchi; Chemistry, Pharmaceutical; Citrulline; Glutamates; Glutamic Acid; Guinea Pigs; Lysine; Ornithine; Peptides; Pharmacology; Research | 1963 |
TRICARBOXYLIC ACID CYCLE MUTANTS IN SACCHAROMYCES: COMPARISON OF INDEPENDENTLY DERIVED MUTANTS.
Topics: Amino Acids; Citric Acid Cycle; Cytochromes; Glutamates; Glutamic Acid; Hydro-Lyases; Ketoglutaric Acids; Lysine; Mutation; Peptides; Research; Saccharomyces; Saccharomyces cerevisiae | 1965 |
Amino acid requirements for maintenance in the adult rooster. II. The requirements for glutamic acid, histidine, lysine and arginine.
Topics: Animals; Arginine; Chickens; Diet; Glutamates; Glutamic Acid; Histidine; Lysine; Male; Nutrition Assessment; Nutritional Status | 1959 |
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages].
Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen | 2003 |
[LysB3, GluB29] insulin: a novel insulin analog with enhanced beta-cell protective action.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Cytokines; DNA Fragmentation; Dose-Response Relationship, Drug; Fatty Acids; Glutamic Acid; Humans; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Islets of Langerhans; Lysine; Nucleosomes; Palmitic Acid; Phosphoproteins; Phosphorylation; Precipitin Tests; Rats; Tyrosine | 2003 |
Calcium-dependent molecular spring elements in the giant protein titin.
Topics: Amino Acid Motifs; Amino Acid Sequence; Calcium; Connectin; Exons; Gene Deletion; Glutamic Acid; Humans; Lysine; Molecular Sequence Data; Muscle Proteins; Muscles; Mutagenesis, Site-Directed; Proline; Protein Conformation; Protein Kinases; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Valine | 2003 |
N-terminal modifications increase the neutral-pH stability of pepsin.
Topics: Alanine; Amino Acid Substitution; Animals; Catalysis; Circular Dichroism; Enzyme Activation; Enzyme Stability; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Lysine; Mutagenesis, Site-Directed; Pepsin A; Pepsinogen A; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Structure-Activity Relationship; Substrate Specificity; Swine; Threonine | 2003 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Embryonic lethal effect of expressing a dominant negative mutant human thyroid hormone receptor alpha1 in mice.
Topics: Animals; Embryo, Mammalian; Fetal Death; Gene Expression; Genes, Dominant; Glutamic Acid; Humans; Lysine; Male; Mice; Mice, Transgenic; Mutation; Peptide Elongation Factor 1; Phenylalanine; Protein Subunits; Thyroid Hormone Receptors alpha; Transgenes | 2003 |
Detailed analysis of the effects of Glu/Lys beta69 human leukocyte antigen-DP polymorphism on peptide-binding specificity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Cell Line, Tumor; Glutamic Acid; HLA-DP Antigens; Humans; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Polymorphism, Genetic; Protein Binding; Recombinant Proteins | 2003 |
Electrochemiluminescent biosensors array for the concomitant detection of choline, glucose, glutamate, lactate, lysine and urate.
Topics: Biosensing Techniques; Choline; Complex Mixtures; Electrochemistry; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Glucose; Glutamic Acid; Lactic Acid; Luminescent Measurements; Lysine; Oxidoreductases; Protein Array Analysis; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Uric Acid | 2003 |
New oxazole-based peptidomimetics: useful building blocks for the synthesis of orthogonally protected macrocyclic scaffolds.
Topics: Biomimetic Materials; Glutamic Acid; Heterocyclic Compounds; Lysine; Molecular Structure; Oxazoles; Peptides | 2003 |
In vitro comparison of the efficacy of Carisolv and conventional rotary instrument in caries removal.
Topics: Dental Caries; Dental Instruments; Dental Restoration, Permanent; Dentin; Gels; Glutamic Acid; Humans; Leucine; Lysine; Molar | 2003 |
Microtensile bond strengths to caries-affected dentine treated with Carisolv.
Topics: Adhesiveness; Adhesives; Chi-Square Distribution; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Restoration, Permanent; Dentin; Glass Ionomer Cements; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Methacrylates; Microscopy, Electron, Scanning; Resin Cements; Resins, Synthetic; Surface Properties; Tensile Strength | 2003 |
Comparative study of carious dentin removal by Er,Cr:YSGG laser and Carisolv.
Topics: Dental Caries; Dental Cavity Preparation; Dental High-Speed Technique; Dentin; Glutamic Acid; Humans; Laser Therapy; Leucine; Lysine; Microscopy; Treatment Outcome | 2003 |
Salt bridges do not stabilize polyproline II helices.
Topics: Circular Dichroism; Computer Simulation; Glutamic Acid; Hydrogen Bonding; Lysine; Models, Molecular; Monte Carlo Method; Oligopeptides; Peptides; Protein Structure, Secondary; Salts | 2003 |
High-probability uniquantal transmission at excitatory synapses in barrel cortex.
Topics: Action Potentials; Analysis of Variance; Animals; Axons; Calcium; Dendrites; Dipeptides; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Image Processing, Computer-Assisted; In Vitro Techniques; Kynurenic Acid; Lysine; Patch-Clamp Techniques; Probability; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glutamate; Somatosensory Cortex; Synapses; Synaptic Transmission | 2003 |
The entire cDNA sequences of projectin isoforms of crayfish claw closer and flexor muscles and their localization.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Astacoidea; Caenorhabditis elegans Proteins; Calmodulin-Binding Proteins; DNA, Complementary; Glutamic Acid; Lysine; Molecular Sequence Data; Muscle Proteins; Muscles; Protein Isoforms; Sarcomeres | 2003 |
Detection of alpha-helical coiled-coil dimer formation by spin-labeled synthetic peptides: a model parallel coiled-coil peptide and the antiparallel coiled coil formed by a replica of the ProP C-terminus.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Dimerization; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary; Spin Labels; Symporters | 2003 |
Roles of N-terminal region residues Lys11, Arg13, and Arg24 of antithrombin in heparin recognition and in promotion and stabilization of the heparin-induced conformational change.
Topics: Alanine; Amino Acid Substitution; Antithrombins; Arginine; Aspartic Acid; Glutamic Acid; Heparin; Humans; Ions; Kinetics; Lysine; Oligosaccharides; Peptide Fragments; Protease Inhibitors; Protein Binding; Protein Conformation; Protein Structure, Tertiary | 2004 |
Superoxide reductase from Desulfoarculus baarsii: identification of protonation steps in the enzymatic mechanism.
Topics: Alanine; Amino Acid Substitution; Deltaproteobacteria; Desulfovibrio vulgaris; Enzyme Stability; Glutamic Acid; Hydrogen-Ion Concentration; Isoleucine; Lysine; Oxidation-Reduction; Oxidoreductases; Protons; Pulse Radiolysis; Recombinant Proteins; Spectrum Analysis; Superoxides | 2004 |
The novel neurofilament light (NEFL) mutation Glu397Lys is associated with a clinically and morphologically heterogeneous type of Charcot-Marie-Tooth neuropathy.
Topics: Adult; Aged; Aged, 80 and over; Axons; Charcot-Marie-Tooth Disease; Deafness; DNA Mutational Analysis; Female; Genetic Testing; Glutamic Acid; Humans; Lysine; Male; Microscopy, Electron; Middle Aged; Muscle Weakness; Mutation; Neural Conduction; Neurofilament Proteins; Pedigree; Peripheral Nerves; Phenotype; Protein Structure, Tertiary; Sural Nerve | 2004 |
Family of cytochrome c7-type proteins from Geobacter sulfurreducens: structure of one cytochrome c7 at 1.45 A resolution.
Topics: Amino Acid Sequence; Binding Sites; Chromates; Crystallization; Crystallography, X-Ray; Cytochrome c Group; Deoxycholic Acid; Desulfuromonas; Geobacter; Glutamic Acid; Heme; Hydrophobic and Hydrophilic Interactions; Lysine; Molecular Sequence Data; Polymers; Protein Structure, Secondary; Repetitive Sequences, Amino Acid; Sequence Homology, Amino Acid | 2004 |
The impact of Lys-->Arg surface mutations on the crystallization of the globular domain of RhoGDI.
Topics: Alanine; Arginine; Crystallization; Crystallography, X-Ray; Epitopes; Escherichia coli; Glutamic Acid; Guanine Nucleotide Dissociation Inhibitors; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; rho Guanine Nucleotide Dissociation Inhibitor alpha; rho-Specific Guanine Nucleotide Dissociation Inhibitors; Temperature | 2004 |
Genetic screening for melanocortin-4 receptor mutations in a cohort of Italian obese patients: description and functional characterization of a novel mutation.
Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Animals; Child; Chlorocebus aethiops; Cohort Studies; COS Cells; Female; Genetic Testing; Glutamic Acid; Heterozygote; Humans; Italy; Lysine; Male; Middle Aged; Mutation; Mutation, Missense; Obesity; Pedigree; Phenylalanine; Receptor, Melanocortin, Type 4; Serine | 2004 |
Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family.
Topics: Adult; Africa; Aged; Cell Line; Diabetes Mellitus; Female; Founder Effect; Glucose Intolerance; Glucose Tolerance Test; Glutamic Acid; Haplotypes; HeLa Cells; Homeodomain Proteins; Humans; India; Lysine; Male; Middle Aged; Mutation; Mutation, Missense; Pedigree; Trans-Activators; Transcriptional Activation; Trinidad and Tobago | 2004 |
Lys9 for Glu9 substitution in glucagon-like peptide-1(7-36)amide confers dipeptidylpeptidase IV resistance with cellular and metabolic actions similar to those of established antagonists glucagon-like peptide-1(9-36)amide and exendin (9-39).
Topics: Adenylyl Cyclases; Amino Acid Substitution; Animals; Blood Glucose; Cells, Cultured; Cricetinae; Cyclic AMP; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Fibroblasts; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Glutamic Acid; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Lung; Lysine; Mice; Mice, Obese; Peptide Fragments; Peptides; Receptors, Glucagon; Spectrometry, Mass, Electrospray Ionization | 2004 |
Molecular simulations suggest protein salt bridges are uniquely suited to life at high temperatures.
Topics: Computer Simulation; Glutamic Acid; Hot Temperature; Hydrophobic and Hydrophilic Interactions; Lysine; Models, Molecular; Proteins; Salts; Thermodynamics | 2004 |
Mutational analysis of different regions in the coxsackievirus 2B protein: requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication.
Topics: Amino Acid Sequence; Animals; Arginine; Asparagine; Aspartic Acid; Cell Line; Cell Membrane; Chlorocebus aethiops; COS Cells; Dimerization; DNA Mutational Analysis; Enterovirus; Glutamic Acid; Hygromycin B; Kinetics; Lysine; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Oligonucleotides, Antisense; Permeability; Protein Structure, Tertiary; RNA; Subcellular Fractions; Time Factors; Transfection; Tryptophan; Two-Hybrid System Techniques; Viral Nonstructural Proteins; Virus Replication | 2004 |
The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatin; Gene Deletion; Glutamic Acid; Green Fluorescent Proteins; Histones; Humans; Kinetics; Luminescent Proteins; Lysine; Mice; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Spectrometry, Fluorescence; Threonine; Time Factors; Transfection | 2004 |
Function of conserved residues of human glutathione synthetase: implications for the ATP-grasp enzymes.
Topics: Adenosine Triphosphate; Asparagine; Binding Sites; Catalysis; Circular Dichroism; Conserved Sequence; Crystallography, X-Ray; DNA; Glutamic Acid; Glutathione; Glutathione Synthase; Humans; Kinetics; Ligands; Lysine; Models, Chemical; Models, Molecular; Multigene Family; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Recombinant Proteins; Software | 2004 |
The ionic track in the F1-ATPase from the thermophilic Bacillus PS3.
Topics: Adenosine Diphosphate; Amino Acid Substitution; Arginine; Bacillus; Bacterial Proton-Translocating ATPases; Catalytic Domain; Copper; Cysteine; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Lysine; Methylation; Mutagenesis, Site-Directed; Protein Subunits; Sodium-Potassium-Exchanging ATPase; Temperature | 2004 |
Pi-helix preference in unsolvated peptides.
Topics: Alanine; Gases; Glutamic Acid; Glycine; Lysine; Models, Molecular; Peptides; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Thermodynamics | 2004 |
The effects of a caries-removing gel (Carisolv) on FM3A cell-line in vitro.
Topics: Animals; Cell Division; Cell Line, Tumor; Cell Survival; Dental Cavity Preparation; Glutamic Acid; Leucine; Lysine; Mice | 2004 |
Microtubule-kinesin interface mutants reveal a site critical for communication.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Animals; Binding Sites; Catalysis; Cell Communication; Drosophila Proteins; Glutamic Acid; Hydrolysis; Kinesins; Kinetics; Lysine; Microtubules; Molecular Motor Proteins; Mutagenesis, Site-Directed; ortho-Aminobenzoates | 2004 |
Role of Arg100 in the active site of adenosylcobalamin-dependent glutamate mutase.
Topics: Arginine; Bacterial Proteins; Binding Sites; Catalysis; Cobamides; Deuterium; Glutamic Acid; Hydrogen Bonding; Intramolecular Transferases; Kinetics; Lysine; Mutagenesis, Site-Directed; N-Methylaspartate; Spectrophotometry; Substrate Specificity; Vitamin B 12 | 2004 |
Effect of Carisolv on the human dental pulp: a histological study.
Topics: Adolescent; Child; Compomers; Dental Cavity Lining; Dental Cavity Preparation; Dental Pulp; Dental Pulp Exposure; Dental Restoration, Permanent; Dentin; Follow-Up Studies; Glass Ionomer Cements; Glutamic Acid; Hemorrhage; Hemostatics; Humans; Leucine; Lysine; Odontoblasts; Polytetrafluoroethylene; Pulpitis; Sodium Chloride; Time Factors | 2004 |
Amino terminal glutamate residues confer spermine sensitivity and affect voltage gating and channel conductance of rat connexin40 gap junctions.
Topics: Algorithms; Animals; Blotting, Western; Connexin 43; Connexins; DNA, Complementary; Gap Junction alpha-5 Protein; Gap Junctions; Glutamic Acid; Ion Channel Gating; Lysine; Membrane Potentials; Mice; Mutation; Patch-Clamp Techniques; Quaternary Ammonium Compounds; Spermine | 2004 |
Domain structures and roles in bacteriophage HK97 capsid assembly and maturation.
Topics: Asparagine; Aspartic Acid; Capsid; Coliphages; Crystallization; Cysteine; Glutamic Acid; Lysine; Protein Precursors; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Virus Assembly | 2004 |
Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1.
Topics: Alleles; Arginine; Case-Control Studies; Cholangitis, Sclerosing; Cohort Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glycine; Haplotypes; HLA Antigens; Homozygote; Humans; Intercellular Adhesion Molecule-1; Lysine; Polymorphism, Genetic; Primed In Situ Labeling | 2004 |
Morphology and electrophysiology of neurons in dog paraventricular nucleus: in vitro study.
Topics: Action Potentials; Animals; Axons; Calcium Signaling; Cell Membrane; Cell Size; Dendrites; Dogs; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Lysine; Male; Neurons; Paraventricular Hypothalamic Nucleus; Reaction Time; Synaptic Transmission | 2004 |
Identification of the catalytic residues involved in the carboxyl transfer of pyruvate carboxylase.
Topics: Acetyl-CoA Carboxylase; Aspartic Acid; Bacillus; Carboxy-Lyases; Carboxyl and Carbamoyl Transferases; Carrier Proteins; Catalytic Domain; Chromatography, Gel; Chromatography, High Pressure Liquid; Circular Dichroism; Conserved Sequence; Enzyme Activation; Fatty Acid Synthase, Type II; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Oxamic Acid; Protein Structure, Tertiary; Pyruvate Carboxylase; Pyruvic Acid; Tritium | 2004 |
Comparison of the glutamate-, arginine- and lysine-dependent acid resistance systems in Escherichia coli O157:H7.
Topics: Amino Acids; Arginine; Culture Media; Dose-Response Relationship, Drug; Escherichia coli O157; Food Microbiology; Glutamic Acid; Hydrogen-Ion Concentration; Lysine | 2004 |
Comparison of the efficacy of chemomechanical caries removal (Carisolv) with that of conventional excavation in reducing the cariogenic flora.
Topics: Bacteria; Child; Child, Preschool; Colony Count, Microbial; Dental Caries; Dental Cavity Preparation; Dentin; Glutamic Acid; Humans; Lactobacillus; Leucine; Lysine; Microscopy, Electron, Scanning | 2004 |
Polymorphisms of the prion protein gene (PRNP) in a Korean population.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Codon; Gene Frequency; Genotype; Glutamic Acid; Heterozygote; Homozygote; Humans; Korea; Lysine; Methionine; Molecular Sequence Data; Open Reading Frames; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prions; Valine | 2004 |
Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.
Topics: Amino Acid Sequence; Animals; Binding Sites; Breast Neoplasms; Constitutive Androstane Receptor; Cysteine; Dimerization; Drug Stability; Glutamic Acid; Humans; Isoleucine; Leucine; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Sequence Alignment; Signal Transduction; Structure-Activity Relationship; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2004 |
The importance of a critical protonation state and the fate of the catalytic steps in class A beta-lactamases and penicillin-binding proteins.
Topics: Amino Acid Motifs; Bacterial Proteins; beta-Lactamases; Binding Sites; Carrier Proteins; Catalysis; Cloning, Molecular; Cysteine; Escherichia coli; Genetic Vectors; Glutamic Acid; Hexosyltransferases; Hydrogen-Ion Concentration; Ions; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Muramoylpentapeptide Carboxypeptidase; Mutation; Penicillin-Binding Proteins; Peptidyl Transferases; Protein Binding; Protons; Serine; Thermodynamics | 2004 |
Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).
Topics: Amino Acids; Arginine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cells, Cultured; Glutamic Acid; Humans; Lysine; Membrane Proteins; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Transfection | 2004 |
K317, R319, and E320 within the proximal C-terminus of the bradykinin B2 receptor form a motif important for phospholipase C and phospholipase A2 but not connective tissue growth factor related signaling.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Arachidonic Acid; Arginine; Connective Tissue Growth Factor; Endocytosis; Glutamic Acid; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Rats; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Structure-Activity Relationship; Type C Phospholipases | 2004 |
Association of aldehyde dehydrogenase-2 polymorphism with alcoholic polyneuropathy in humans.
Topics: Action Potentials; Alcoholic Neuropathy; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Neural Conduction; Peripheral Nerves; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Mutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues.
Topics: Cell Differentiation; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Ibotenic Acid; Immunohistochemistry; Kinetics; Ligands; Lysine; Models, Chemical; Models, Genetic; Models, Molecular; Mutation; Point Mutation; Protein Binding; Protein Conformation; Quisqualic Acid; Receptors, Metabotropic Glutamate; Serine; Transfection | 2004 |
A severe form of amyloidotic polyneuropathy in a Costa Rican family with a rare transthyretin mutation (Glu54Lys).
Topics: Adult; Amyloidosis; Base Sequence; Blotting, Western; Coloring Agents; Congo Red; Costa Rica; DNA; DNA Mutational Analysis; Exons; Family Health; Female; Glutamic Acid; Humans; Immunohistochemistry; Lysine; Male; Molecular Sequence Data; Mouth Mucosa; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Polyneuropathies; Prealbumin | 2004 |
Biochemistry. De novo design of an enzyme.
Topics: Algorithms; Amino Acid Substitution; Binding Sites; Catalysis; Computational Biology; Computer Simulation; Directed Molecular Evolution; Escherichia coli Proteins; Glutamic Acid; Glyceraldehyde 3-Phosphate; Histidine; Hydrogen Bonding; Lysine; Models, Molecular; Periplasmic Binding Proteins; Protein Conformation; Protein Engineering; Triose-Phosphate Isomerase | 2004 |
Kinetic studies of Thermobifida fusca Cel9A active site mutant enzymes.
Topics: Actinomycetales; Amino Acid Substitution; Arginine; Aspartic Acid; Bacterial Proteins; Binding Sites; Carboxymethylcellulose Sodium; Cellulase; Enzyme Activation; Fibronectins; Glutamic Acid; Kinetics; Leucine; Lysine; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Deletion; Substrate Specificity; Threonine; Tyrosine | 2004 |
ZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation.
Topics: Blotting, Western; Cell Line; Cell Line, Tumor; Chromatin; DNA-Binding Proteins; Gene Expression Regulation; Genes, Dominant; Genes, Reporter; Glutamic Acid; HeLa Cells; Humans; Immunoprecipitation; Kruppel-Like Transcription Factors; Luciferases; Lysine; Mutagenesis, Site-Directed; Plasmids; Promoter Regions, Genetic; Protein Binding; Protein Inhibitors of Activated STAT; Protein Structure, Tertiary; Proteins; Proto-Oncogene Proteins p21(ras); SUMO-1 Protein; TATA-Box Binding Protein; Time Factors; Trans-Activators; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53; Two-Hybrid System Techniques; Ubiquitin-Protein Ligases | 2004 |
Residues Lys-149 and Glu-153 switch the aminoacylation of tRNA(Trp) in Bacillus subtilis.
Topics: Acylation; Bacillus subtilis; Glutamic Acid; Lysine; Mutagenesis, Site-Directed; Phylogeny; RNA, Bacterial; RNA, Transfer, Trp; Sequence Alignment; Species Specificity; Tryptophan-tRNA Ligase | 2004 |
The Candida albicans pH-regulated KER1 gene encodes a lysine/glutamic-acid-rich plasma-membrane protein that is involved in cell aggregation.
Topics: Animals; Base Sequence; Candida albicans; Cloning, Molecular; DNA, Fungal; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Membrane Proteins; Mice; Mice, Inbred DBA; Molecular Sequence Data; Phenotype; Subcellular Fractions; Virulence | 2004 |
The ER22/23EK polymorphism in the glucocorticoid receptor gene is associated with a beneficial body composition and muscle strength in young adults.
Topics: Adolescent; Adult; Anthropometry; Arginine; Body Composition; Female; Genotype; Glutamic Acid; Heterozygote; Humans; Lysine; Male; Motor Activity; Muscle, Skeletal; Polymorphism, Genetic; Puberty; Receptors, Glucocorticoid | 2004 |
Studies of SpoIIAB mutant proteins elucidate the mechanisms that regulate the developmental transcription factor sigmaF in Bacillus subtilis.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; Arginine; Bacillus subtilis; Bacterial Proteins; Glutamic Acid; Kinetics; Lysine; Multiprotein Complexes; Mutation; Nucleotides; Phenotype; Phosphorylation; Sigma Factor; Threonine | 2004 |
Interaction of aluminium ions with some amino acids present in human blood.
Topics: Aluminum; Amino Acids; Aspartic Acid; Chromatography; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Copper; Filtration; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Ions; Ligands; Lysine; Metals; o-Phthalaldehyde; Ornithine; Spectrophotometry, Atomic; Tyrosine | 2004 |
The effect of sugar, amino acid, metal ion, and NaCl on model Maillard reaction under pH control.
Topics: Alanine; Amino Acids; Arabinose; Arginine; Aspartic Acid; Biochemistry; Carbohydrates; Colorimetry; Copper; Cysteine; Fructose; Glucose; Glutamic Acid; Glycine max; Hot Temperature; Hydrogen-Ion Concentration; Ions; Iron; Isoleucine; Leucine; Lysine; Maltose; Metals; Models, Chemical; Phenylalanine; Proline; Serine; Sodium Chloride; Temperature; Time Factors; Valine; Xylose | 2004 |
Mutation E522K in human DNA topoisomerase IIbeta confers resistance to methyl N-(4'-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4'-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide.
Topics: Amino Acid Sequence; Amsacrine; Antineoplastic Agents; DNA; DNA Topoisomerases, Type II; Enzyme Stability; Etoposide; Glutamic Acid; Humans; Lysine; Models, Molecular; Mutation; Topoisomerase II Inhibitors; Tranexamic Acid | 2004 |
Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel.
Topics: Amino Acid Substitution; Animals; Binding Sites; Electrophysiology; Glutamic Acid; Lidocaine; Lysine; Mutagenesis, Site-Directed; Oocytes; Sodium Channel Blockers; Sodium Channels; Xenopus laevis | 2004 |
Properties of P-glycoprotein with mutations in the "catalytic carboxylate" glutamate residues.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Carboxylic Acids; Catalysis; Dimerization; Dithiothreitol; Dose-Response Relationship, Drug; Glutamic Acid; Hydrolysis; Kinetics; Lipid Metabolism; Lysine; Mice; Models, Chemical; Mutation; Pichia; Protein Conformation; Protein Structure, Tertiary; Time Factors; Vanadates | 2004 |
Reaction intermediates in the catalytic mechanism of Escherichia coli MutY DNA glycosylase.
Topics: Adenine; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; DNA; DNA Glycosylases; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Guanine; Kinetics; Lysine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Time Factors | 2004 |
Follow-up of nemaline myopathy in two patients with novel mutations in the skeletal muscle alpha-actin gene (ACTA1).
Topics: Actins; Aspartic Acid; DNA Mutational Analysis; Exons; Female; Follow-Up Studies; Genetic Carrier Screening; Glutamic Acid; Glycine; Heterozygote; Humans; Lysine; Male; Microscopy, Electron; Muscle, Skeletal; Mutation; Myopathies, Nemaline | 2004 |
Angiotensin II excites paraventricular nucleus neurons that innervate the rostral ventrolateral medulla: an in vitro patch-clamp study in brain slices.
Topics: Anesthetics, Local; Angiotensin II; Animals; Blood Pressure; Cadmium; Diagnostic Imaging; Dose-Response Relationship, Drug; Drug Interactions; Electric Impedance; Glutamic Acid; In Vitro Techniques; Lysine; Male; Medulla Oblongata; Membrane Potentials; Neural Conduction; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Tetrodotoxin; Time Factors; Vasoconstrictor Agents | 2005 |
Stabilization of beta-hairpin peptides by salt bridges: role of preorganization in the energetic contribution of weak interactions.
Topics: Amino Acid Sequence; Glutamic Acid; Kinetics; Lysine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Conformation; Protein Folding; Protein Structure, Secondary; Serine; Static Electricity; Thermodynamics | 2003 |
Influence of chemo-mechanical caries removal on the surface topography of dental composite resin and glass-ionomer materials: an in vitro study.
Topics: Compomers; Composite Resins; Dental Cavity Preparation; Dental Materials; Dental Restoration, Permanent; Desiccation; Glass Ionomer Cements; Glutamic Acid; Humans; Interferometry; Leucine; Lysine; Maleates; Materials Testing; Surface Properties; Wettability | 2004 |
Osmosensitivity associated with insertions in argP (iciA) or glnE in glutamate synthase-deficient mutants of Escherichia coli.
Topics: DNA Transposable Elements; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Glutamate Synthase; Glutamic Acid; Lysine; Nucleotidyltransferases; Quaternary Ammonium Compounds; Sodium Chloride | 2004 |
Synthesis of Nepsilon-protected-L-lysine and gamma-benzyl-L-glutamate N-carboxyanhydrides (NCA) by carbamoylation and nitrosation.
Topics: Anhydrides; Carbon; Cyanates; Glutamic Acid; Lysine; Models, Chemical; Nitric Oxide; Nitrogen; Oxazoles; Oxygen; Polylysine; Polymers; Spectrophotometry; Temperature | 2004 |
Definition of the structural elements in plasminogen required for high-affinity binding to apolipoprotein(a): a study utilizing surface plasmon resonance.
Topics: Animals; Apolipoproteins A; Binding Sites; Cells, Cultured; Cricetinae; Enzyme Activation; Glutamic Acid; Ligands; Lysine; Plasminogen; Protein Binding; Spectrometry, Fluorescence; Surface Plasmon Resonance | 2004 |
Crystal structures of HbA2 and HbE and modeling of hemoglobin delta 4: interpretation of the thermal stability and the antisickling effect of HbA2 and identification of the ferrocyanide binding site in Hb.
Topics: Alternative Splicing; Antisickling Agents; Binding Sites; Crystallization; Crystallography, X-Ray; Ferrocyanides; Glutamic Acid; Hemoglobin A2; Hemoglobin E; Hemoglobins; Humans; Hydrogen-Ion Concentration; Lysine; Methemoglobin; Models, Molecular; Mutation; Protein Denaturation; Protein Processing, Post-Translational; Protein Subunits; Thermodynamics | 2004 |
Muscarinic toxin 7 selectivity is dictated by extracellular receptor loops.
Topics: Amino Acid Sequence; Animals; Binding Sites; Calcium; Cell Line; Dose-Response Relationship, Drug; Elapid Venoms; Glutamic Acid; Humans; Insecta; Kinetics; Ligands; Lysine; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Recombinant Proteins; Sequence Homology, Amino Acid; Time Factors | 2004 |
The Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based newborn screening, is temperature sensitive.
Topics: Acyl-CoA Dehydrogenase; Amino Acid Substitution; Animals; Circular Dichroism; Enzyme Stability; Escherichia coli; Fibroblasts; Glutamic Acid; Histidine; Humans; Infant, Newborn; Lymphocytes; Lysine; Mitochondria, Liver; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Neonatal Screening; Oxidation-Reduction; Rats; Recombinant Proteins; Structure-Activity Relationship; Tyrosine | 2004 |
The ND1 gene of complex I is a mutational hot spot for Leber's hereditary optic neuropathy.
Topics: Adult; Aged; DNA Mutational Analysis; DNA, Mitochondrial; Family Health; Female; Ferricyanides; Glutamic Acid; Haplotypes; Humans; Inhibitory Concentration 50; Lysine; Magnetic Resonance Spectroscopy; Male; Microscopy, Electron, Transmission; Middle Aged; Mitochondria, Muscle; Models, Molecular; Muscle, Skeletal; Mutation; NAD; NADH Dehydrogenase; Occipital Lobe; Optic Atrophy, Hereditary, Leber; Pedigree; Polymorphism, Restriction Fragment Length; Radionuclide Imaging; Rotenone; Sequence Analysis, Protein; Succinate Dehydrogenase; Visual Acuity; Visual Fields | 2004 |
Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cations, Monovalent; Citrobacter freundii; Enzyme Activation; Glutamic Acid; Histidine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Potassium; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Tyrosine Phenol-Lyase | 2004 |
Identification of a new point mutation in hypoxanthine phosphoribosyl transferase responsible for hyperuricemia in a female patient.
Topics: Adenosine; Adult; DNA, Complementary; Female; Glutamic Acid; Guanine; Humans; Hyperuricemia; Hypoxanthine Phosphoribosyltransferase; Lysine; Point Mutation; Sequence Analysis, DNA | 2004 |
Jak2 tyrosine kinase residues glutamic acid 1024 and arginine 1113 form a hydrogen bond interaction that is essential for Jak-STAT signal transduction.
Topics: Alanine; Algorithms; Amino Acid Sequence; Angiotensin II; Animals; Arginine; Blotting, Western; Cell Line; COS Cells; Crystallography, X-Ray; Cytoplasm; DNA-Binding Proteins; Gene Expression Regulation; Genes, Dominant; Glutamic Acid; Hydrogen Bonding; Immunoprecipitation; Janus Kinase 2; Luciferases; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; STAT1 Transcription Factor; Structure-Activity Relationship; Trans-Activators; Transfection; Tyrosine | 2004 |
Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Amino Acid Motifs; Arginine; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Endonucleases; Gamma Rays; Genetic Complementation Test; Glutamic Acid; Lysine; Mutation; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombination, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors | 2005 |
Nonspecific interstitial pneumonia, alveolar proteinosis, and abnormal proprotein trafficking resulting from a spontaneous mutation in the surfactant protein C gene.
Topics: Blotting, Western; Bronchoalveolar Lavage; Cell Line, Tumor; DNA; DNA Primers; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Green Fluorescent Proteins; Humans; Immunoblotting; Immunohistochemistry; Infant; Lung; Lung Diseases, Interstitial; Lysine; Male; Microscopy, Fluorescence; Microscopy, Immunoelectron; Microscopy, Phase-Contrast; Models, Biological; Mutation; Phospholipids; Protein Transport; Pulmonary Alveolar Proteinosis; Pulmonary Surfactant-Associated Protein C; Recombinant Fusion Proteins; Surface-Active Agents; Time Factors; Tomography, X-Ray Computed; Transfection | 2005 |
The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals.
Topics: Alkanes; Animals; Bicuculline; Bungarotoxins; Chromatography, High Pressure Liquid; Cyclopropanes; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Hippocampus; In Vitro Techniques; Indoles; Linoleic Acid; Lysine; Male; Maleimides; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Nicotinic; Receptors, Presynaptic; Synaptic Transmission; Valine | 2005 |
Oxygen reactions in p-hydroxybenzoate hydroxylase utilize the H-bond network during catalysis.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Amino Acid Substitution; Catalysis; Glutamic Acid; Glutamine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxylation; Lysine; Methionine; Oxidation-Reduction; Phenylalanine; Pseudomonas aeruginosa; Pseudomonas fluorescens; Tyrosine | 2004 |
A single amino acid change (E85K) in human PCNA that leads, relative to wild type, to enhanced DNA synthesis by DNA polymerase delta past nucleotide base lesions (TLS) as well as on unmodified templates.
Topics: Amino Acid Substitution; DNA Damage; DNA Polymerase III; DNA Replication; Glutamic Acid; Humans; Lysine; Mutagenesis; Point Mutation; Proliferating Cell Nuclear Antigen; Templates, Genetic | 2004 |
Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase.
Topics: Adenosine Triphosphate; Ammonium Chloride; Archaea; Asparaginase; Aspartic Acid; Binding Sites; Chromatography, Thin Layer; Cloning, Molecular; Enzyme Activation; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Hydrolysis; Lysine; Methanobacteriaceae; Models, Chemical; Mutation; Phosphorylation; Protein Biosynthesis; Protein Kinases; Pyrrolidonecarboxylic Acid; RNA, Transfer; RNA, Transfer, Gln; Threonine | 2005 |
The E46K mutation in alpha-synuclein increases amyloid fibril formation.
Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Amyloid; Blotting, Western; Calpain; Chromatography, Gel; Circular Dichroism; DNA, Complementary; Glutamic Acid; Humans; Kinetics; Lysine; Microscopy, Electron; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Protein Conformation; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Synucleins; Time Factors | 2005 |
Analysis of glutamine accumulation in rat brain mitochondria in the presence of a glutamine uptake inhibitor, histidine, reveals glutamine pools with a distinct access to deamidation.
Topics: Amides; Animals; Arginine; Brain Chemistry; Cerebral Cortex; Glutamic Acid; Glutamine; Hippocampus; Histidine; Lysine; Male; Mitochondria; Rats | 2004 |
Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway.
Topics: Alanine; Amidohydrolases; Asparagine; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Gram-Negative Bacteria; Histidine; Hydrogen-Ion Concentration; Kinetics; Lipid A; Lysine; Mutagenesis, Site-Directed; Substrate Specificity; Zinc | 2005 |
Coassembly of amphiphiles with opposite peptide polarities into nanofibers.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Circular Dichroism; Fluorenes; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Molecular Sequence Data; Nanostructures; Nuclear Magnetic Resonance, Biomolecular; Palmitic Acid; Peptides; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared | 2005 |
Structure-guided mutational analysis of the nucleotidyltransferase domain of Escherichia coli NAD+-dependent DNA ligase (LigA).
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Anti-Infective Agents; Arginine; Binding Sites; Cloning, Molecular; DNA; DNA Ligases; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Enterococcus faecalis; Escherichia coli; Glutamic Acid; Lysine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Mutation, Missense; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structure-Activity Relationship; Time Factors | 2005 |
Proton pathways in green fluorescence protein.
Topics: Animals; Aspartic Acid; Binding Sites; Biophysics; Crystallography, X-Ray; Cytoplasm; Databases, Protein; Glutamic Acid; Glutamine; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Light; Lysine; Models, Chemical; Models, Molecular; Mutation; Nitrogen; Point Mutation; Protein Conformation; Protons; Scyphozoa; Solvents; Spectrophotometry; Threonine; Time Factors; Tyrosine; Water; X-Rays | 2005 |
Electrostatic interactions involving lysine make major contributions to collagen triple-helix stability.
Topics: Amino Acid Motifs; Arginine; Aspartic Acid; Collagen; Computer Simulation; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Lysine; Models, Molecular; Peptide Fragments; Protein Structure, Secondary; Sequence Analysis, Protein; Static Electricity; Thermodynamics | 2005 |
Comparison of chemomechanical caries removal using Carisolv or conventional hand excavation in deciduous teeth in vitro.
Topics: Dental Caries; Dental Cavity Preparation; Dentin; Glutamic Acid; Hardness; Humans; Leucine; Lysine; Time Factors; Tooth, Deciduous | 2005 |
Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins.
Topics: Complement C3b Inactivator Proteins; Complement Inactivator Proteins; Complement Pathway, Alternative; Complement Pathway, Classical; Consensus Sequence; Glutamic Acid; Humans; Lysine; Models, Molecular; Orthopoxvirus; Peptide Mapping; Point Mutation; Predictive Value of Tests; Protein Binding; Repetitive Sequences, Amino Acid; Static Electricity; Variola virus; Viral Proteins | 2005 |
Novel mutation in the Per-Arnt-Sim domain of KCNH2 causes a malignant form of long-QT syndrome.
Topics: Adult; Blotting, Western; Cell Line; Death, Sudden, Cardiac; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Glutamic Acid; Humans; Kidney; Long QT Syndrome; Lysine; Male; Microscopy, Confocal; Middle Aged; Mutation, Missense; Patch-Clamp Techniques; Pedigree; Peptides; Phenotype; Piperidines; Potassium Channels, Voltage-Gated; Protein Structure, Tertiary; Proteins; Pyridines | 2005 |
Deciphering structure and topology of conserved COG2042 orphan proteins.
Topics: Amino Acid Sequence; Archaeal Proteins; Arginine; Biophysics; Biotin; Chromatography, Gel; Circular Dichroism; Cloning, Molecular; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Kinetics; Lysine; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Peptide Hydrolases; Peptides; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinimides; Sulfolobus solfataricus | 2005 |
First-choice treatment alternatives for caries removal using the chemomechanical method.
Topics: Adolescent; Adult; Child; Dental Caries; Dental Cavity Preparation; Dental Enamel; Dental Restoration, Permanent; Dentin; Equipment Design; Glutamic Acid; Humans; Leucine; Lysine; Tooth Demineralization | 2005 |
Mutations in senataxin responsible for Quebec cluster of ataxia with neuropathy.
Topics: Adult; Aged; alpha-Fetoproteins; Apraxias; Arginine; Ataxia; Chromosomes, Human, Pair 9; Cluster Analysis; DNA Helicases; DNA Mutational Analysis; Family Health; Female; Glutamic Acid; Humans; Leucine; Linkage Disequilibrium; Lysine; Male; Middle Aged; Multifunctional Enzymes; Mutation; Oculomotor Nerve Diseases; Quebec; RNA Helicases | 2005 |
Functional consequences of G alpha 13 mutations that disrupt interaction with p115RhoGEF.
Topics: Amino Acid Substitution; Arginine; Binding Sites; Cell Line; Cloning, Molecular; Glutamic Acid; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; Humans; Kidney; Lysine; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Rho Guanine Nucleotide Exchange Factors; Transfection | 2005 |
The conserved histidine 295 does not contribute to proton cotransport by the glutamate transporter EAAC1.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Biological Transport, Active; Cell Line; Conserved Sequence; Cysteine; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Patch-Clamp Techniques; Protons; Rats; Symporters; Transfection | 2005 |
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; DNA Polymerase beta; Enzyme Activation; Enzyme Stability; Escherichia coli Proteins; Genetic Complementation Test; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Isoleucine; Lysine; Peptide Fragments; Phenotype; Protein Folding; Protein Structure, Tertiary; Rats; Substrate Specificity | 2005 |
Functional characterization of XendoU, the endoribonuclease involved in small nucleolar RNA biosynthesis.
Topics: Amino Acid Sequence; Animals; Catalysis; Catalytic Domain; Cloning, Molecular; DNA Primers; Endoribonucleases; Glutamic Acid; Histidine; Introns; Lysine; Manganese; Molecular Sequence Data; Mutation; Oligopeptides; Phylogeny; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA, Small Nuclear; Sequence Homology, Amino Acid; Substrate Specificity; Transcription, Genetic; Xenopus; Xenopus laevis; Xenopus Proteins | 2005 |
A lysine- and glutamic acid-rich protein, KERP1, from Entamoeba histolytica binds to human enterocytes.
Topics: Amino Acid Sequence; Animals; Caco-2 Cells; Entamoeba histolytica; Enterocytes; Glutamic Acid; Humans; Lysine; Membrane Proteins; Microscopy, Electron, Transmission; Microvilli; Molecular Sequence Data; Protozoan Proteins | 2005 |
Interaction between interleukin-6 and intercellular adhesion molecule-1 genes and Alzheimer's disease risk.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chi-Square Distribution; Confidence Intervals; Female; Genotype; Glutamic Acid; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Lysine; Male; Meta-Analysis as Topic; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk | 2005 |
Site-directed mutagenesis of active site residues of phosphite dehydrogenase.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Deuterium Exchange Measurement; Diethyl Pyrocarbonate; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; Phosphites; Sequence Alignment | 2005 |
Influence of Carisolv on resin adhesion for two different adhesive systems to sound human primary dentin and young permanent dentin.
Topics: Acid Etching, Dental; Bicuspid; Bisphenol A-Glycidyl Methacrylate; Composite Resins; Dental Bonding; Dental Cavity Preparation; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Methacrylates; Microscopy, Electron, Scanning; Molar; Resin Cements; Stress, Mechanical; Surface Properties; Tooth, Deciduous | 2005 |
Glyoxal inactivates glutamate transporter-1 in cultured rat astrocytes.
Topics: Amino Acid Transport System X-AG; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Glutamic Acid; Glyoxal; Immunoblotting; Immunohistochemistry; Lysine; Rats | 2005 |
Are acidic and basic groups in buried proteins predicted to be ionized?
Topics: Amino Acids, Acidic; Amino Acids, Basic; Arginine; Aspartic Acid; Crystallography; Glutamic Acid; Ions; Lysine; Proteins; Static Electricity | 2005 |
Zero-length cross-linking reveals that tight interactions between the extracellular and transmembrane domains of the luteinizing hormone receptor persist during receptor activation.
Topics: Aspartic Acid; Binding Sites; Blotting, Western; Cell Membrane; Cell Separation; Cross-Linking Reagents; Cyclic AMP; Disulfides; Dose-Response Relationship, Drug; Flow Cytometry; Furin; Glutamic Acid; Humans; Immunoblotting; Lysine; Models, Biological; Protein Binding; Protein Structure, Tertiary; Receptors, LH; Recombinant Proteins; Time Factors; Transfection | 2005 |
Single amino acid substitution in the putative transmembrane helix V in KdpB of the KdpFABC complex of Escherichia coli uncouples ATPase activity and ion transport.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport, Active; Cation Transport Proteins; Cations, Monovalent; Enzyme Activation; Escherichia coli Proteins; Genetic Complementation Test; Glutamic Acid; Hydrolysis; Ion Channel Gating; Lysine; Membrane Proteins; Mutagenesis, Site-Directed; Potassium; Protein Structure, Secondary; Protein Subunits; Proteolipids; Vanadates | 2005 |
Carisolv: an alternative to NaOCl in immature root canals?
Topics: Animals; Dental Pulp Cavity; Glutamic Acid; Leucine; Lysine; Materials Testing; Microscopy, Electron, Scanning; Random Allocation; Root Canal Irrigants; Root Canal Preparation; Sheep; Sheep, Domestic; Smear Layer; Sodium Hypochlorite; Statistics, Nonparametric; Tooth Root | 2005 |
The in vitro performance of laser fluorescence and caries-detector dye for detecting residual carious dentin during tooth preparation.
Topics: Coloring Agents; Dental Caries; Dental Caries Activity Tests; Dental Cavity Preparation; Dentin; Fluorescence; Glutamic Acid; Humans; Lasers; Leucine; Lysine; Microscopy, Polarization; Molar; Observer Variation; Reproducibility of Results; Sensitivity and Specificity | 2005 |
A mutation in bovine keratin 5 causing epidermolysis bullosa simplex, transmitted by a mosaic sire.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Animals, Newborn; Cattle; Cattle Diseases; Chromosome Mapping; Epidermolysis Bullosa Simplex; Female; Glutamic Acid; Keratin-5; Keratins; Lysine; Male; Microscopy, Electron; Mosaicism; Mutation; Pedigree | 2005 |
Isolation rearing or methamphetamine traumatisation induce a "dysconnection" of prefrontal efferents in gerbils: implications for schizophrenia.
Topics: Animals; Central Nervous System Stimulants; Cerebral Cortex; Disease Models, Animal; Dopamine; Efferent Pathways; Gerbillinae; Glutamic Acid; Lysine; Male; Methamphetamine; Models, Neurological; Parietal Lobe; Prefrontal Cortex; Presynaptic Terminals; Schizophrenia; Social Isolation; Synaptic Transmission | 2006 |
A nuclear targeting determinant for SATB1, a genome organizer in the T cell lineage.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Lineage; Cell Nucleus; Chromatin; Cytoplasm; Databases, Protein; Genome; Glutamic Acid; Green Fluorescent Proteins; Humans; Lysine; Markov Chains; Matrix Attachment Region Binding Proteins; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Nuclear Localization Signals; Nuclear Matrix; Phylogeny; Point Mutation; Protein Binding; Protein Structure, Tertiary; Protein Transport; Pyruvate Kinase; Sequence Homology, Amino Acid; T-Lymphocytes; Transfection | 2005 |
Molecular dynamics study of water penetration in staphylococcal nuclease.
Topics: Algorithms; Computer Simulation; Crystallography, X-Ray; Glutamic Acid; Hydrogen; Hydrogen Bonding; Kinetics; Lysine; Micrococcal Nuclease; Models, Molecular; Molecular Conformation; Protein Conformation; Protein Structure, Secondary; Proteomics; Software; Solvents; Static Electricity; Thermodynamics; Time Factors; Water | 2005 |
Functional hierarchy of plasminogen kringles 1 and 4 in fibrinolysis and plasmin-induced cell detachment and apoptosis.
Topics: Animals; Antibodies, Monoclonal; Antifibrinolytic Agents; Apoptosis; Binding Sites; Cell Adhesion; CHO Cells; Cricetinae; Fibrin; Fibrinolysin; Fibrinolysis; Glutamic Acid; Humans; Kringles; Lysine; Peptide Fragments; Plasminogen; Protein Binding; Protein Conformation; Recombinant Proteins | 2005 |
Lysine and glutamate production by Corynebacterium glutamicum on glucose, fructose and sucrose: roles of malic enzyme and fructose-1,6-bisphosphatase.
Topics: Bacterial Proteins; Carbohydrate Metabolism; Carbohydrates; Corynebacterium glutamicum; Culture Media; Fructose-Bisphosphatase; Gene Expression; Glutamic Acid; Lysine; Malate Dehydrogenase | 2005 |
Amino acid substitutions in the pore of the Ca(V)1.2 calcium channel reduce barium currents without affecting calcium currents.
Topics: Amino Acid Sequence; Barium; Biological Transport; Calcium; Calcium Channels; Calcium Channels, L-Type; Cations; Cations, Divalent; Cell Line; DNA, Complementary; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Ion Channel Gating; Ions; Kinetics; Lysine; Membrane Potentials; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Tyrosine | 2005 |
Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase "Asian" variant.
Topics: Aldehyde Dehydrogenase; Arginine; Binding Sites; Crystallography, X-Ray; Dimerization; DNA, Complementary; Glutamic Acid; Humans; Hydrogen Bonding; Kinetics; Lysine; Mitochondria; Models, Molecular; NAD; Protein Binding; Protein Conformation; Protein Structure, Tertiary | 2005 |
Mutational analysis of the human 2B4 (CD244)/CD48 interaction: Lys68 and Glu70 in the V domain of 2B4 are critical for CD48 binding and functional activation of NK cells.
Topics: Alanine; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Surface; CD48 Antigen; Cytotoxicity, Immunologic; Dimerization; DNA Mutational Analysis; Down-Regulation; Glutamic Acid; Humans; Immunosuppressive Agents; Killer Cells, Natural; Lymphocyte Activation; Lysine; Melanoma, Experimental; Membrane Glycoproteins; Mice; Molecular Sequence Data; Protein Binding; Protein Structure, Tertiary; Receptors, Immunologic; Recombinant Fusion Proteins; Signaling Lymphocytic Activation Molecule Family | 2005 |
An intact phosphocholine binding site is necessary for transgenic rabbit C-reactive protein to protect mice against challenge with platelet-activating factor.
Topics: Animals; Binding Sites; C-Reactive Protein; Complement Activation; Dietary Carbohydrates; Dietary Proteins; Glutamic Acid; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenylalanine; Phosphorylcholine; Platelet Activating Factor; Protein Binding; Rabbits; Survival Analysis; Tyrosine | 2005 |
Characterization of the E-138 (Glu/Lys) mutation in Japanese encephalitis virus by using a stable, full-length, infectious cDNA clone.
Topics: Animals; Cells, Cultured; Chlorocebus aethiops; DNA Mutational Analysis; DNA, Complementary; Encephalitis Virus, Japanese; Encephalitis, Japanese; Female; Glutamic Acid; Heparin; Lysine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Plasmids; Polysaccharide-Lyases; RNA, Viral; Transfection; Vero Cells; Viral Envelope Proteins; Virulence; Virus Replication | 2005 |
Orientation-dependent potential of mean force for protein folding.
Topics: Arginine; Crystallization; Databases, Protein; Glutamic Acid; Hydrogen Bonding; Lysine; Models, Chemical; Models, Statistical; Molecular Conformation; Phenylalanine; Polymers; Protein Folding; Proteins; Solvents | 2005 |
Functional interconnectivity between the globus pallidus and the subthalamic nucleus in the mouse brain slice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Apamin; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Globus Pallidus; Glutamic Acid; In Vitro Techniques; Lysine; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Net; Neurons; Picrotoxin; Subthalamic Nucleus | 2005 |
Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate.
Topics: Alkylating Agents; Amino Acid Substitution; Animals; Arginine; Base Sequence; Deoxycytosine Nucleotides; Deoxyguanosine; DNA Damage; DNA Polymerase beta; DNA Primers; Glutamic Acid; Lysine; Methionine; Methylnitrosourea; Molecular Sequence Data; Protein Structure, Tertiary; Rats; Substrate Specificity; Templates, Genetic; Thymine Nucleotides | 2005 |
Apparent pKa shifts of titratable residues at high denaturant concentration and the impact on protein stability.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Glutamic Acid; Guanidine; Histidine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Protein Folding; Proteins; Sensitivity and Specificity; Titrimetry; Urea | 2005 |
Water chain formation and possible proton pumping routes in Rhodobacter sphaeroides cytochrome c oxidase: a molecular dynamics comparison of the wild type and R481K mutant.
Topics: Arginine; Computer Simulation; Electron Transport Complex IV; Glutamic Acid; Heme; Hydrogen Bonding; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Propionates; Protein Structure, Secondary; Proton Pumps; Rhodobacter sphaeroides; Thermodynamics; Water | 2005 |
The penC mutation conferring antibiotic resistance in Neisseria gonorrhoeae arises from a mutation in the PilQ secretin that interferes with multimer stability.
Topics: Amino Acid Substitution; Drug Resistance, Bacterial; Fimbriae Proteins; Fimbriae, Bacterial; Glutamic Acid; Lysine; Mutation, Missense; Neisseria gonorrhoeae; Penicillins; Transformation, Bacterial | 2005 |
Effectiveness of Carisolv compared with sodium hypochlorite and calcium hydroxide.
Topics: Calcium Hydroxide; Cariostatic Agents; Chi-Square Distribution; Dental Caries; Dental Cavity Preparation; Fibrillar Collagens; Glutamic Acid; Humans; Leucine; Lysine; Random Allocation; Sodium Hypochlorite | 2005 |
Crystal structure of the first KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.7 A.
Topics: Amino Acid Sequence; Crystallography, X-Ray; Dimerization; DNA; Glutamic Acid; Heterogeneous-Nuclear Ribonucleoprotein K; Humans; Hydrogen Bonding; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; RNA-Binding Proteins; Sequence Homology, Amino Acid; Telomere | 2005 |
Amino acid variation in cellular processes in 108 bacterial proteomes.
Topics: Amino Acid Substitution; Amino Acids; Arginine; Bacteria; Bacterial Proteins; Base Composition; Computational Biology; Genes, Bacterial; Genome, Bacterial; Glutamic Acid; Leucine; Lysine; Mutation; Protein Biosynthesis; Proteome; Selection, Genetic; Signal Transduction; Transcription, Genetic | 2005 |
A novel single-nucleotide substitution, Glu 4 Lys, in the leukotriene C4 synthase gene associated with allergic diseases.
Topics: Adolescent; Adult; Amino Acid Substitution; Asthma; Case-Control Studies; Child; Child, Preschool; Dermatitis, Atopic; Female; Glutamic Acid; Glutathione Transferase; Humans; Hypersensitivity, Immediate; Infant; Lysine; Male; Point Mutation; Respiratory Hypersensitivity | 2005 |
Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.
Topics: Acylation; beta-Lactamases; Glutamic Acid; Lysine; Models, Molecular; Penicillanic Acid; Serine; Thermodynamics | 2005 |
Function of positive charges following signal-anchor sequences during translocation of the N-terminal domain.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Chlorocebus aethiops; Cluster Analysis; COS Cells; Cycloheximide; DNA, Complementary; Dogs; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Gene Deletion; Glutamic Acid; Glycosylation; Lysine; Mice; Microsomes; Models, Biological; Molecular Sequence Data; Mutation; Peptides; Plasmids; Protein Conformation; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Protein Transport; Rabbits; Ribosomes; RNA, Messenger; Sequence Homology, Amino Acid; Synaptotagmin II; Transcription, Genetic | 2006 |
[Cavity micro-morphology following caries removal].
Topics: Dental Caries; Dental Cavity Preparation; Dental High-Speed Technique; Dental Instruments; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Molar; Smear Layer; Sonication; Surface Properties | 2005 |
The nature of the remaining dentin surface following application of Carisolv solution.
Topics: Analysis of Variance; Cariostatic Agents; Dental Caries; Dental Cavity Preparation; Dentin; Glutamic Acid; Hardness; Humans; Leucine; Lysine; Microscopy, Atomic Force; Surface Properties | 2005 |
Mass spectrometric analysis of the ubiquinol-binding site in cytochrome bd from Escherichia coli.
Topics: Amino Acid Sequence; Binding Sites; Chromatography, High Pressure Liquid; Cytochrome b Group; Cytochromes; Dimerization; Electron Transport Chain Complex Proteins; Electrons; Endopeptidases; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Ligands; Light; Lysine; Mass Spectrometry; Metalloendopeptidases; Models, Chemical; Molecular Sequence Data; Oxidoreductases; Peptides; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Ubiquinone; Ultraviolet Rays | 2006 |
Fe3+-hydroxide ligation in the superoxide reductase from Desulfoarculus baarsii is associated with pH dependent spectral changes.
Topics: Alanine; Binding Sites; Deltaproteobacteria; Ferric Compounds; Glutamic Acid; Hydrogen-Ion Concentration; Iron; Isoleucine; Ligands; Lysine; Molecular Structure; Oxidation-Reduction; Oxidoreductases; Oxygen Isotopes; Spectrum Analysis, Raman | 2005 |
The alpha-synuclein mutation E46K promotes aggregation in cultured cells.
Topics: alpha-Synuclein; Blotting, Western; Cell Aggregation; Cell Line, Tumor; Fluorescent Antibody Technique; Glutamic Acid; Green Fluorescent Proteins; Humans; Lysine; Microscopy, Electron, Transmission; Mutagenesis; Mutation; Neuroblastoma; Transfection | 2006 |
Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase.
Topics: Base Sequence; DNA; DNA Primers; DNA, Viral; Drug Resistance, Viral; Frameshift Mutation; Gene Deletion; Genes, Viral; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Lac Operon; Lysine; Models, Genetic; Models, Molecular; Molecular Sequence Data; Mutation; Oligonucleotides; Protein Conformation; Recombinant Proteins; RNA-Directed DNA Polymerase; Templates, Genetic; Virus Replication | 2006 |
Bonding of single-component adhesives to dentin following chemomechanical caries removal.
Topics: Aminobutyrates; Composite Resins; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Restoration, Permanent; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Methacrylates; Microscopy, Electron, Scanning; Resin Cements; Stress, Mechanical; Surface Properties; Tensile Strength | 2005 |
Interruption of pacemaker signals by a diencephalic nucleus in the African electric fish, Gymnarchus niloticus.
Topics: Action Potentials; Animal Communication; Animals; Biological Clocks; Brain Mapping; Diencephalon; Electric Fish; Electric Organ; Glutamic Acid; Iontophoresis; Lysine; Neurons; Social Behavior | 2006 |
Development of selective inhibitors and substrate of matrix metalloproteinase-12.
Topics: Drug Design; Enzyme Inhibitors; Glutamic Acid; Humans; Kinetics; Lysine; Matrix Metalloproteinase 12; Matrix Metalloproteinases; Metalloendopeptidases; Models, Chemical; Models, Molecular; Peptide Library; Peptides; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity; Threonine; Time Factors | 2006 |
Caries removal with Carisolv system: criteria evaluation and microleakage test.
Topics: Cariostatic Agents; Composite Resins; Dental Caries; Dental Caries Activity Tests; Dental Cavity Preparation; Dental Leakage; Dental Marginal Adaptation; Dental Restoration, Permanent; Dentin; Fluorescence; Glutamic Acid; Humans; Leucine; Lysine | 2005 |
Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744.
Topics: Arginine; Cell Line; Computational Biology; Glutamic Acid; Humans; Leukemia, Myeloid, Acute; Ligands; Lysine; Models, Molecular; Phosphopeptides; Phosphotyrosine; Protein Binding; Receptors, Granulocyte Colony-Stimulating Factor; STAT3 Transcription Factor | 2006 |
Mutation of two intramembrane polar residues conserved within the hyaluronan synthase family alters hyaluronan product size.
Topics: Amino Acid Sequence; Cell Membrane; Conserved Sequence; Enzyme Stability; Escherichia coli; Glucuronosyltransferase; Glutamic Acid; Hyaluronan Synthases; Hyaluronic Acid; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Sequence Homology, Amino Acid; Streptococcus equi | 2006 |
Analysis of behavior-related excitatory inputs to a central pacemaker nucleus in a weakly electric fish.
Topics: Action Potentials; Afferent Pathways; Animals; Behavior, Animal; Biological Clocks; Brain; Electric Stimulation; Escape Reaction; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Gymnotiformes; Interneurons; Lysine; Motor Activity; Neurons; Receptors, N-Methyl-D-Aspartate; Reticular Formation; Synaptic Transmission | 2006 |
The effect of intracellular ppGpp levels on glutamate and lysine overproduction in Escherichia coli.
Topics: Amino Acids; Escherichia coli; Glutamic Acid; Guanosine Tetraphosphate; Intracellular Space; Lysine; Transcription Factor RelA; Transformation, Bacterial | 2006 |
Mutation Glu82Lys in lamin A/C gene is associated with cardiomyopathy and conduction defect.
Topics: Adult; Amino Acid Sequence; Amino Acid Substitution; Asian People; Cardiomyopathy, Dilated; Cell Nucleus; Cells, Cultured; Child; Female; Glutamic Acid; Heart Block; Heart Conduction System; Humans; Lamin Type A; Lysine; Male; Membrane Proteins; Molecular Sequence Data; Nuclear Envelope; Nuclear Proteins; Pedigree; Point Mutation; Thymopoietins | 2006 |
The ICAM-1 E469K gene polymorphism is a risk factor for spontaneous cervical artery dissection.
Topics: Adult; Alleles; Amino Acid Substitution; Female; Genotype; Glutamic Acid; Humans; Intercellular Adhesion Molecule-1; Lysine; Male; Polymorphism, Genetic; Risk Factors; Vertebral Artery Dissection | 2006 |
Comparisons of potentials for L-lysine production among different Corynebacterium glutamicum strains.
Topics: Corynebacterium glutamicum; Glutamic Acid; Lysine; Mutation; Temperature | 2006 |
Reaction of rat pulp tissue to Carisolv 'new gel'--a histocytological evaluation.
Topics: Animals; Calcium Hydroxide; Composite Resins; Dental Cavity Preparation; Dental Cements; Dental Leakage; Dental Materials; Dental Pulp; Dental Pulp Capping; Dental Pulp Exposure; Dental Restoration, Permanent; Dentin-Bonding Agents; Female; Gels; Glutamic Acid; Leucine; Lysine; Male; Methacrylates; Rats; Rats, Wistar; Sodium Chloride; Time Factors | 2006 |
Dopamine uptake and cocaine binding mechanisms: the involvement of charged amino acids from the transmembrane domains of the human dopamine transporter.
Topics: Alanine; Amino Acid Substitution; Animals; Arginine; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Kinetics; Lysine; Mutation; Transfection; Tritium | 2006 |
New approach to calculating and predicting the ionic strength generated during carrier ampholyte isoelectric focusing.
Topics: Electrolytes; Glutamic Acid; Isoelectric Focusing; Lysine; Osmolar Concentration | 2006 |
Association of a Glu92Lys substitution in MC1R with extended brown in Japanese quail (Coturnix japonica).
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Animals; Avian Proteins; Color; Coturnix; Glutamic Acid; Lysine; Mutation, Missense; Phenotype; Phylogeny; Receptor, Melanocortin, Type 1; Sequence Alignment; Sequence Analysis, Protein | 2006 |
A variable degree of intrauterine and postnatal growth retardation in a family with a missense mutation in the insulin-like growth factor I receptor.
Topics: Adult; Base Sequence; Body Height; Bone Density; DNA Mutational Analysis; DNA, Complementary; Failure to Thrive; Female; Fetal Growth Retardation; Fibroblasts; Glutamic Acid; Growth Disorders; Heterozygote; Humans; Infant; Insulin-Like Growth Factor I; Lysine; Microcephaly; Mutation, Missense; Phosphorylation; Polymerase Chain Reaction; Receptor, IGF Type 1; Sequence Analysis, DNA; Signal Transduction | 2006 |
Comprehensive examination of charged intramembrane residues in a nucleoside transporter.
Topics: Animals; Aspartic Acid; Biological Transport; Cell Membrane; Glutamic Acid; Leishmania donovani; Lysine; Membrane Transport Modulators; Nucleoside Transport Proteins; Protein Binding; Protein Structure, Tertiary; Protozoan Proteins; Substrate Specificity | 2006 |
Asp302 determines potassium dependence of a RadA recombinase from Methanococcus voltae.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Archaeal Proteins; Aspartic Acid; Crystallography, X-Ray; DNA-Binding Proteins; Electrons; Glutamic Acid; Hydrolysis; Lysine; Methanococcus; Mutation; Potassium; Protein Structure, Secondary; Protein Subunits; Sodium | 2006 |
Antimicrobial actions of benzimidazoles against the oral anaerobes Fusobacterium nucleatum and Prevotella intermedia.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amino Acids; Aminopeptidases; Anaerobiosis; Anti-Infective Agents; Enzyme Inhibitors; Fermentation; Fructose; Fusobacterium nucleatum; Glucose; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Lansoprazole; Lysine; Mouth; Oxygen; Prevotella intermedia; Serine | 2006 |
Differences in protonation of ubiquinone and menaquinone in fumarate reductase from Escherichia coli.
Topics: Binding Sites; Electron Spin Resonance Spectroscopy; Escherichia coli; Glutamic Acid; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Protons; Spectroscopy, Fourier Transform Infrared; Succinate Dehydrogenase; Ubiquinone; Vitamin K 2; Vitamins | 2006 |
A novel mutation in two families with limb-girdle muscular dystrophy type 2C.
Topics: Adolescent; Child; Child, Preschool; Connectin; DNA Mutational Analysis; Exons; Family Health; Female; Glutamic Acid; Humans; Lysine; Male; Muscle Proteins; Muscular Dystrophies, Limb-Girdle; Mutation | 2006 |
Chemo-mechanical dentine caries removal with Carisolv using a rotating brush.
Topics: Coloring Agents; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Dental Instruments; Dentin; Glutamic Acid; Hardness; Humans; Leucine; Lysine; Rotation; Time Factors | 2006 |
MYPT1 mutants demonstrate the importance of aa 888-928 for the interaction with PKGIalpha.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Aorta; Arginine; Chickens; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Gizzard, Avian; Glutamic Acid; Immunoprecipitation; Isoenzymes; Leucine Zippers; Lysine; Muscle, Smooth, Vascular; Mutation; Nitric Oxide; Peptide Fragments; Phosphoprotein Phosphatases; Protein Structure, Tertiary; Vasodilation | 2007 |
Dichotomic phylogenetic tree of the pyruvate kinase family: K+ -dependent and -independent enzymes.
Topics: Amino Acid Sequence; Animals; Binding Sites; Computational Biology; Glutamic Acid; Lysine; Molecular Sequence Data; Multigene Family; Mutagenesis; Phylogeny; Potassium; Protein Binding; Pyruvate Kinase; Rabbits | 2006 |
Osteoporosis associated with gyrate atrophy: a case report.
Topics: Adult; Alanine; Female; Fluorescein Angiography; Glutamic Acid; Gyrate Atrophy; Humans; Lysine; Ornithine; Osteoporosis | 2006 |
Fatal hypertrophic cardiomyopathy and nemaline myopathy associated with ACTA1 K336E mutation.
Topics: Actinin; Actins; Amino Acid Substitution; Cardiomyopathy, Hypertrophic, Familial; Child, Preschool; DNA Mutational Analysis; Fatal Outcome; Genetic Predisposition to Disease; Genetic Testing; Glutamic Acid; Humans; Lysine; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation, Missense; Myocardium; Myopathies, Nemaline | 2006 |
Acute flaccid paralysis as initial symptom in 4 patients with novel E1alpha mutations of the pyruvate dehydrogenase complex.
Topics: Adolescent; Arginine; Child; Child, Preschool; DNA Mutational Analysis; Family Health; Glutamic Acid; Humans; Leucine; Lysine; Magnetic Resonance Imaging; Male; Mutation; Neural Conduction; Protein Subunits; Pyruvate Dehydrogenase Complex; Quadriplegia; Serine | 2006 |
The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant.
Topics: Amino Acid Substitution; Base Sequence; Camptothecin; Catalysis; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Glutamic Acid; Humans; Lysine; Saccharomyces cerevisiae; Substrate Specificity | 2006 |
Generalized epidermolytic hyperkeratosis in two unrelated children from parents with localized linear form, and prenatal diagnosis.
Topics: Adult; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Hyperkeratosis, Epidermolytic; Infant, Newborn; Isoleucine; Keratin-1; Keratin-10; Lysine; Mutation; Phenylalanine; Prenatal Diagnosis; Skin | 2006 |
Observing an induced-fit mechanism during sequence-specific DNA methylation.
Topics: Binding Sites; DNA; DNA Methylation; Glutamic Acid; Kinetics; Lysine; Microscopy, Fluorescence; Models, Genetic; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutation; Nucleic Acid Conformation; Thermodynamics; Tryptophan | 2006 |
Electrostatic potential energy within a protein monitored by metal charge-dependent hydrogen exchange.
Topics: Biophysics; Gallium; Glutamic Acid; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Metals; Models, Molecular; Protein Conformation; Pyrococcus furiosus; Rubredoxins; Static Electricity; Thermodynamics; Zinc | 2006 |
Microhardness and Ca:P ratio of carious and Carisolv treated caries-affected dentine using an ultra-micro-indentation system and energy dispersive analysis of x-rays--a pilot study.
Topics: Adult; Calcium; Dental Caries; Dental Cavity Preparation; Dentin; Elasticity; Electron Probe Microanalysis; Glutamic Acid; Hardness; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Phosphorus; Pilot Projects | 2005 |
The role of Carisolv and different auxiliary chemical substances in the removal of bovine root canal smear layer.
Topics: Animals; Cattle; Citric Acid; Glutamic Acid; Leucine; Lysine; Microscopy, Electron, Scanning; Root Canal Irrigants; Root Canal Preparation; Smear Layer; Sodium Chloride; Sodium Hypochlorite; Statistics, Nonparametric | 2006 |
Rapid PCR-based test for identifying Candida albicans by using primers derived from the pH-regulated KER1 gene.
Topics: Candida albicans; DNA Primers; Fungal Proteins; Genes, Fungal; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Membrane Proteins; Polymerase Chain Reaction | 2006 |
A novel cross-linked RNase A dimer with enhanced enzymatic properties.
Topics: Animals; Cattle; Crystallography, X-Ray; Dimerization; Freeze Drying; Glutamic Acid; Lysine; Mass Spectrometry; Models, Molecular; Protein Conformation; Protein Folding; Ribonuclease, Pancreatic; RNA; RNA, Double-Stranded; Temperature | 2007 |
Toll-like receptor 4 region Glu24-Lys47 is a site for MD-2 binding: importance of CYS29 and CYS40.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cysteine; Glutamic Acid; Humans; Lymphocyte Antigen 96; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2006 |
Right-handed DNA supercoiling by an octameric form of histone-like protein HU: modulation of cellular transcription.
Topics: Carrier Proteins; Chromatin; Dimerization; DNA-Binding Proteins; DNA, Superhelical; Escherichia coli Proteins; Genetic Markers; Glutamic Acid; Histones; Leucine; Lysine; Microscopy, Atomic Force; Mutation; Protein Isoforms; Transcription Factors; Valine | 2006 |
Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleosides; Dideoxynucleotides; Drug Resistance, Multiple, Viral; Genotype; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lysine; Mutagenesis, Site-Directed; Organophosphonates; Phenotype; Reverse Transcriptase Inhibitors; Tenofovir; Thymine Nucleotides; Zidovudine | 2007 |
Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei.
Topics: Action Potentials; Animals; Cell Shape; Cerebellar Nuclei; Dendrites; Efferent Pathways; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Immunohistochemistry; Interneurons; Lysine; Mice; Mice, Transgenic; Neural Inhibition; Neural Pathways; Organ Culture Techniques; Patch-Clamp Techniques; Recombinant Fusion Proteins; Synaptic Transmission | 2007 |
Two Finnish USH1B patients with three novel mutations in myosin VIIA.
Topics: Amino Acid Substitution; Codon, Nonsense; Dyneins; Female; Finland; Frameshift Mutation; Gene Deletion; Glutamic Acid; Glutamine; Heterozygote; Humans; Lysine; Male; Mutation; Myosin VIIa; Myosins; Pedigree; Usher Syndromes | 2006 |
Recent H5N1 avian influenza A virus increases rapidly in virulence to mice after a single passage in mice.
Topics: Adaptation, Biological; Amino Acid Substitution; Animals; Brain; Chickens; Glutamic Acid; Histocytochemistry; Immunohistochemistry; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Lysine; Mice; Mutation, Missense; Orthomyxoviridae Infections; RNA, Viral; Viral Proteins; Virulence | 2006 |
The spectral studies on the effect of Glu 101 to the metal binding characteristic of Euplotes octocarinatus centrin.
Topics: Animals; Electrophoresis, Polyacrylamide Gel; Euplotes; Glutamic Acid; Kinetics; Lysine; Naphthalenesulfonates; Protozoan Proteins; Structure-Activity Relationship; Terbium; Titrimetry | 2007 |
Identification and quantitative studies of protein immobilization sites by stable isotope labeling and mass spectrometry.
Topics: Amino Acid Sequence; Glutamic Acid; Humans; Isotope Labeling; Lysine; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
Mechanism of dihydroneopterin aldolase: functional roles of the conserved active site glutamate and lysine residues.
Topics: Aldehyde-Lyases; Amino Acid Sequence; Binding Sites; Catalysis; Conserved Sequence; Escherichia coli Proteins; Glutamic Acid; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Staphylococcus aureus; Structure-Activity Relationship; Substrate Specificity | 2006 |
Efficacy of bioactive polypeptides on bleeding and intra-abdominal adhesions.
Topics: Abdomen; Animals; Glutamic Acid; Injections, Intraperitoneal; Intraoperative Complications; Liver; Lysine; Mice; Mice, Inbred Strains; Peptides; Postoperative Hemorrhage; Spleen; Tissue Adhesions; Wound Healing | 2007 |
Cardiac-specific overexpression of E40K active Akt prevents pressure overload-induced heart failure in mice by increasing angiogenesis and reducing apoptosis.
Topics: Animals; Apoptosis; Blood Pressure; Cardiac Output, Low; Coronary Circulation; Gene Expression Regulation; Glutamic Acid; Lysine; Mice; Myocardium; Myocytes, Cardiac; Neovascularization, Physiologic; Proto-Oncogene Proteins c-akt; RNA, Messenger; Vascular Endothelial Growth Factor A | 2007 |
Basis for the equilibrium constant in the interconversion of l-lysine and l-beta-lysine by lysine 2,3-aminomutase.
Topics: Glutamic Acid; Hydrogen-Ion Concentration; Intramolecular Transferases; Ions; Kinetics; Lysine; Stereoisomerism | 2007 |
Mutational epitope analysis and cross-reactivity of two isoforms of Api g 1, the major celery allergen.
Topics: Allergens; Amino Acid Substitution; Antigens, Plant; Apium; Cross Reactions; Epitope Mapping; Food Hypersensitivity; Glutamic Acid; Humans; Immunodominant Epitopes; Immunoglobulin E; Lysine; Mutation; Plant Proteins; Protein Conformation; Protein Folding; Protein Isoforms; Recombinant Proteins | 2007 |
Morphology and electrophysiological properties of hamster spinal dorsal horn neurons that express VGLUT2 and enkephalin.
Topics: Action Potentials; Animals; Cell Shape; Cricetinae; Dendrites; Enkephalins; Glutamic Acid; Immunohistochemistry; Lysine; Male; Mesocricetus; Microscopy, Confocal; Neural Pathways; Patch-Clamp Techniques; Posterior Horn Cells; Presynaptic Terminals; Synaptic Membranes; Synaptic Transmission; Vesicular Glutamate Transport Protein 2 | 2007 |
Crystal structure of Helicobacter pylori formamidase AmiF reveals a cysteine-glutamate-lysine catalytic triad.
Topics: Amidohydrolases; Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Glutamic Acid; Helicobacter pylori; Ligands; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Sequence Homology, Amino Acid | 2007 |
Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway.
Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Norway; Parkinson Disease; Polymorphism, Genetic; Protein Serine-Threonine Kinases | 2007 |
Cold exposure and associated metabolic changes in adult tropical beetles exposed to fluctuating thermal regimes.
Topics: Acclimatization; Alanine; Amino Acids; Amino Acids, Essential; Animals; Arginine; Body Temperature; Cold Temperature; Glucose; Glutamic Acid; Glutamine; Glycerol; Inositol; Lysine; Proline; Ribitol; Sorbitol; Survival Analysis; Temperature; Tenebrio; Threonine; Trehalose; Tropical Climate; Valine | 2007 |
Characterization of the novel defective CYP2C9*24 allele.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Cell Line; Cytochrome P-450 CYP2C9; Glutamic Acid; Humans; Lysine; Microsomes; Mutation; Protein Folding; Saccharomyces cerevisiae | 2007 |
Two Norwegian sisters with late onset Creutzfeldt-Jakob disease caused by the E200K mutation.
Topics: Aged, 80 and over; Creutzfeldt-Jakob Syndrome; Female; Glutamic Acid; Humans; Lysine; Mutation; Norway; Prions; Siblings | 2007 |
Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Antigens, Surface; Bacterial Outer Membrane Proteins; Bacterial Vaccines; Borrelia burgdorferi; Crystallography, X-Ray; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Lipoproteins; Lysine; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Protein Denaturation; Protein Folding; Protein Structure, Secondary | 2007 |
Micro-computed tomographic evaluation of a new enzyme solution for caries removal in deciduous teeth.
Topics: Dental Caries; Dental Cavity Preparation; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Pepsin A; Surface Properties; Tomography, X-Ray Computed; Tooth, Deciduous | 2006 |
Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels.
Topics: Anesthetics, Local; Arginine; Aspartic Acid; Binding Sites; Cell Line; Cell Membrane Permeability; Glutamic Acid; Humans; Ion Channel Gating; Kinetics; Lidocaine; Lysine; Membrane Potentials; Models, Molecular; Molecular Structure; Muscle Proteins; Mutagenesis, Site-Directed; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenylalanine; Protein Conformation; Sodium Channel Blockers; Sodium Channels; Static Electricity; Transfection | 2007 |
Analysis of the novel factor X gene mutation Glu51Lys in two families with factor X-Riyadh anomaly.
Topics: Adolescent; Adult; Aged; Child; DNA Mutational Analysis; Exons; Factor X; Factor X Deficiency; Female; Genotype; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Mutation, Missense; Partial Thromboplastin Time; Pedigree; Phenotype; Prothrombin Time; Saudi Arabia | 2007 |
The key role of the mycolic acid content in the functionality of the cell wall permeability barrier in Corynebacterineae.
Topics: Amino Acids; Anti-Bacterial Agents; Bacterial Proteins; Cell Wall; Corynebacterium glutamicum; Galactans; Gene Deletion; Glucosyltransferases; Glutamic Acid; Glycerol; Lysine; Magnetic Resonance Spectroscopy; Mycolic Acids; Permeability; Trehalose | 2007 |
The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation.
Topics: Animals; Cell Transformation, Neoplastic; DNA Polymerase beta; DNA Primers; DNA Repair; Embryo, Mammalian; Fibroblasts; Glutamic Acid; Humans; Lysine; Methyl Methanesulfonate; Mice; Mutant Proteins; Sister Chromatid Exchange; Stomach Neoplasms; Uracil | 2007 |
Chemical versus conventional caries removal techniques in primary teeth: a microhardness study.
Topics: Dental Caries; Dental Cavity Preparation; Dentin; Glutamic Acid; Hardness; Humans; Incisor; Leucine; Lysine; Papain; Tooth, Deciduous | 2007 |
Artificial plaque removal with Carisolv system: a clinical approach.
Topics: Acid Etching, Dental; Dental Fissures; Dental Plaque; Dental Prophylaxis; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Smear Layer | 2007 |
In vitro effectiveness of a chemo-mechanical method for caries removal.
Topics: Child; Child, Preschool; Dental Caries; Dental Cavity Preparation; Dental High-Speed Technique; Dentin; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Surface Properties | 2007 |
Crystal structure of LL-diaminopimelate aminotransferase from Arabidopsis thaliana: a recently discovered enzyme in the biosynthesis of L-lysine by plants and Chlamydia.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Catalysis; Chlamydia; Crystallography, X-Ray; Diaminopimelic Acid; Dimerization; Glutamic Acid; Lysine; Malates; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Protein Subunits; Pyridoxal Phosphate; Sequence Alignment; Sequence Homology, Amino Acid; Solvents; Static Electricity; Substrate Specificity; Transaminases | 2007 |
Myosin storage myopathy with cardiomyopathy.
Topics: Cardiac Myosins; Cardiomyopathies; Glutamic Acid; Humans; Lysine; Mutation, Missense; Myosin Heavy Chains | 2007 |
Myosin regulatory light chain E22K mutation results in decreased cardiac intracellular calcium and force transients.
Topics: Amino Acid Substitution; Animals; Calcium; Down-Regulation; Female; Glutamic Acid; Humans; Intracellular Fluid; Lysine; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Myosin Light Chains | 2007 |
Fibromodulin binds collagen type I via Glu-353 and Lys-355 in leucine-rich repeat 11.
Topics: Binding Sites; Chondroitin Sulfate Proteoglycans; Collagen Type I; Extracellular Matrix Proteins; Fibromodulin; Glutamic Acid; Humans; Keratan Sulfate; Leucine-Rich Repeat Proteins; Lumican; Lysine; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Proteoglycans | 2007 |
A case of major form familial hyperekplexia: prenatal diagnosis and effective treatment with clonazepam.
Topics: Anticonvulsants; Child, Preschool; Clonazepam; Family Health; Female; Glutamic Acid; Humans; Lysine; Male; Muscle Hypertonia; Point Mutation; Pregnancy; Prenatal Diagnosis; Receptors, Glycine; Reflex, Abnormal | 2007 |
Variable stability heterodimeric coiled-coils from manipulation of electrostatic interface residue chain length.
Topics: Amino Acid Sequence; beta-Alanine; Dimerization; Glutamic Acid; Lysine; Molecular Sequence Data; Nitrilotriacetic Acid; Organometallic Compounds; Peptides; Protein Structure, Secondary; Static Electricity | 2007 |
Acute cocaine exposure alters spine density and long-term potentiation in the ventral tegmental area.
Topics: Action Potentials; Animals; Cell Shape; Cocaine; Cocaine-Related Disorders; Dendritic Spines; Dopamine; Dopamine Uptake Inhibitors; Glutamic Acid; Long-Term Potentiation; Lysine; Male; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Synapses; Synaptic Transmission; Ventral Tegmental Area | 2007 |
CHMP4B, a novel gene for autosomal dominant cataracts linked to chromosome 20q.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cataract; Chromosomes, Human, Pair 20; Endosomal Sorting Complexes Required for Transport; Genes, Dominant; Genetic Linkage; Glutamic Acid; Humans; Lens, Crystalline; Lod Score; Lysine; Molecular Sequence Data; Mutation, Missense; Pedigree; Polymorphism, Single Nucleotide; Transfection | 2007 |
Characterization of glycation adducts on human serum albumin by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Amino Acid Sequence; Carbohydrate Metabolism; Carbohydrates; Glutamic Acid; Glycation End Products, Advanced; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Trypsin | 2007 |
Effect of lysine side chain length on intra-helical glutamate--lysine ion pairing interactions.
Topics: Amino Acid Sequence; Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Molecular Sequence Data; Peptides; Protein Structure, Secondary; Salts; Structure-Activity Relationship | 2007 |
HCCS loss-of-function missense mutation in a female with bilateral microphthalmia and sclerocornea: a novel gene for severe ocular malformations?
Topics: Abnormalities, Multiple; Adenine; Amino Acid Substitution; Animals; CHO Cells; Chromosomes, Human, X; Cohort Studies; Cornea; Cricetinae; Cricetulus; Eye Abnormalities; Female; Glutamic Acid; Guanine; Heterozygote; Humans; Lyases; Lysine; Microphthalmos; Mutation, Missense; Point Mutation; Saccharomyces cerevisiae; Severity of Illness Index; Transfection; X Chromosome Inactivation | 2007 |
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan | 2007 |
Site-directed mutations in the C-terminal extension of human alphaB-crystallin affect chaperone function and block amyloid fibril formation.
Topics: alpha-Crystallin B Chain; Amyloid; Codon; Glutamic Acid; Humans; Lysine; Molecular Chaperones; Mutagenesis, Site-Directed; Mutation; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Spectrometry, Mass, Electrospray Ionization; Temperature | 2007 |
Simulation of charge effects on density maps obtained by high-resolution electron crystallography.
Topics: Computer Simulation; Crystallography; Electrons; Glutamic Acid; Lysine; Models, Chemical; Scattering, Radiation; Static Electricity | 2007 |
Effect of amino acids and antibodies against nerve growth factor receptors on the development of organotypic culture of lymphoid tissue.
Topics: Amino Acids; Animals; Antibodies, Monoclonal; Asparagine; Cell Proliferation; Glutamic Acid; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Nerve Growth Factor; Spleen | 2007 |
KCNJ11 E23K polymorphism and diabetes mellitus with adult onset in Czech patients.
Topics: Adult; Age of Onset; C-Peptide; Case-Control Studies; Czech Republic; Diabetes Mellitus; Female; Gene Frequency; Genotype; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Polymorphism, Single Nucleotide; Potassium Channels, Inwardly Rectifying | 2007 |
Structural basis for catalysis by onconase.
Topics: Adenosine Monophosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Catalysis; Crystallography, X-Ray; Disulfides; Glutamic Acid; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; K562 Cells; Kinetics; Lysine; Models, Biological; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Ribonucleases; Sequence Homology, Amino Acid; Substrate Specificity; X-Ray Diffraction | 2008 |
Auditory nerve is affected in one of two different point mutations of the neurofilament light gene.
Topics: Acoustic Stimulation; Adolescent; Adult; Aged; Charcot-Marie-Tooth Disease; Evoked Potentials, Auditory, Brain Stem; Family Health; Female; Functional Laterality; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Neurofilament Proteins; Point Mutation; Proline; Reaction Time; Serine; Vestibulocochlear Nerve | 2008 |
Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2).
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Computational Biology; Endoribonucleases; Escherichia coli; Fluorides; Glutamic Acid; Guanosine Diphosphate; Histidine; Lysine; Molecular Sequence Data; Mutation; Phosphines; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Messenger; Sequence Deletion | 2008 |
Structural basis for lower lysine methylation state-specific readout by MBT repeats of L3MBTL1 and an engineered PHD finger.
Topics: Amino Acid Sequence; Antigens, Nuclear; Chromosomal Proteins, Non-Histone; Crystallography, X-Ray; DNA Mutational Analysis; Glutamic Acid; Histones; Humans; Kinetics; Lysine; Methylation; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Neoplasm Proteins; Nerve Tissue Proteins; Peptides; Protein Engineering; Protein Structure, Tertiary; Repetitive Sequences, Amino Acid; Repressor Proteins; Structure-Activity Relationship; Transcription Factors; Tumor Suppressor Proteins; Tyrosine | 2007 |
Use of 2-D DIGE analysis reveals altered phosphorylation in a tropomyosin mutant (Glu54Lys) linked to dilated cardiomyopathy.
Topics: Amino Acid Substitution; Animals; Cardiomyopathy, Dilated; Electrophoresis, Gel, Two-Dimensional; Glutamic Acid; Immunoblotting; Lysine; Mice; Mice, Transgenic; Phosphorylation; Point Mutation; Tropomyosin | 2008 |
A novel polymorphism, E254K, in the 5-lipoxygenase gene associated with bronchial asthma.
Topics: Arachidonate 5-Lipoxygenase; Asthma; Base Sequence; Child; DNA Mutational Analysis; Female; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Predisposition to Disease; Glutamic Acid; Humans; Ionomycin; Leukotriene B4; Leukotriene E4; Lysine; Male; Models, Molecular; Molecular Sequence Data; Neutrophils; Polymorphism, Genetic; RNA, Messenger; Structural Homology, Protein | 2008 |
Activating E17K mutation in the gene encoding the protein kinase AKT1 in a subset of squamous cell carcinoma of the lung.
Topics: Aged; Amino Acid Substitution; Base Sequence; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA Mutational Analysis; Enzyme Activation; Glutamic Acid; Humans; Lung Neoplasms; Lysine; Male; Molecular Sequence Data; Mutation; Protein Transport; Proto-Oncogene Proteins c-akt | 2008 |
Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cell Cycle Proteins; Chromatin Immunoprecipitation; Glaucoma, Open-Angle; Glutamic Acid; Humans; Lysine; Membrane Transport Proteins; Molecular Sequence Data; Mutation; Protein Serine-Threonine Kinases; Transcription Factor TFIIIA; Two-Hybrid System Techniques | 2008 |
Genotype-phenotype correlation in a family with primary cortisol resistance: possible modulating effect of the ER22/23EK polymorphism.
Topics: Adrenal Gland Diseases; Adult; Amino Acid Substitution; Arginine; Family; Genetic Diseases, Inborn; Genotype; Glutamic Acid; Heterozygote; Homozygote; Humans; Hydrocortisone; Lysine; Male; Phenotype; Polymorphism, Genetic; Receptors, Glucocorticoid | 2008 |
Identification of regions required for apical membrane localization of human multidrug resistance protein 2.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Azides; Baculoviridae; Cell Line; Cell Membrane; Cell Polarity; Cytoplasm; Dogs; Epithelial Cells; Glutamic Acid; Glutathione; Glycine; Humans; Leukotriene C4; LLC-PK1 Cells; Lysine; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Sequence Homology, Amino Acid; Spodoptera; Swine; Transfection | 2008 |
Evaluation of residual dentin after conventional and chemomechanical caries removal using SEM.
Topics: Adolescent; Child; Child, Preschool; Composite Resins; Dental Bonding; Dental Care for Children; Dental Caries; Dental Cavity Preparation; Dental Instruments; Dental Marginal Adaptation; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; In Vitro Techniques; Incisor; Leucine; Lysine; Papain; Surface Properties; Tooth, Deciduous | 2008 |
Mutational analysis of oncogenic AKT E17K mutation in common solid cancers and acute leukaemias.
Topics: Acute Disease; Adenocarcinoma; Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Leukemia; Liver Neoplasms; Lung Neoplasms; Lysine; Male; Middle Aged; Mutation; Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Proteins c-akt; Stomach Neoplasms | 2008 |
Proline-glutamic acid-proline-lysine repetition peptide as an antigen for the serological diagnosis of strangles.
Topics: Analysis of Variance; Animals; Antibodies, Bacterial; Antigens, Bacterial; Enzyme-Linked Immunosorbent Assay; Glutamic Acid; Horse Diseases; Horses; Immune Sera; Japan; Lysine; Peptides; Proline; Streptococcal Infections; Streptococcus equi | 2008 |
Efficacy of chemo-mechanical caries removal with Carisolv.
Topics: Adolescent; Adult; Child; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Molar; Time Factors | 2008 |
Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation.
Topics: Aged; Amino Acid Substitution; Anus Neoplasms; Benzamides; Dose-Response Relationship, Drug; Female; Glutamic Acid; Humans; Imatinib Mesylate; Intestinal Mucosa; Lysine; Melanoma; Neoplasm Metastasis; Piperazines; Point Mutation; Proto-Oncogene Proteins c-kit; Pyrimidines; Remission Induction | 2008 |
A single amino acid substitution in one of the lipases of Aspergillus nidulans confers resistance to the antimycotic drug undecanoic acid.
Topics: Amino Acid Sequence; Amino Acids; Antifungal Agents; Aspergillus nidulans; Carboxylic Ester Hydrolases; Catalytic Domain; Drug Resistance, Fungal; Fatty Acids; Genetic Techniques; Glutamic Acid; Ions; Lipase; Lysine; Models, Genetic; Molecular Sequence Data; Sequence Homology, Amino Acid | 2008 |
Comparison of the antimicrobial efficacy of chemomechanical caries removal (Carisolv) with that of conventional drilling in reducing cariogenic flora.
Topics: Child; Child, Preschool; Colony Count, Microbial; Dental Cavity Preparation; Dental High-Speed Technique; Dentin; Female; Glutamic Acid; Humans; Lactobacillus; Leucine; Lysine; Male | 2008 |
Effects of surface-to-volume ratio of proteins on hydrophilic residues: decrease in occurrence and increase in buried fraction.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Databases, Protein; Glutamic Acid; Glutamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Linear Models; Lysine; Mathematics; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Structure-Activity Relationship | 2008 |
The energy landscape of a selective tumor-homing pentapeptide.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Computer Simulation; Glutamic Acid; Lysine; Molecular Sequence Data; Nanoparticles; Neoplasm Proteins; Oligopeptides; Peptide Fragments; Protein Structure, Secondary; Solutions; Thermodynamics; Time Factors; Water | 2008 |
[Comparative studies of carious defects filling using the classical method and dental drill, and using the Carisolv chemomechanical method and the YAG:Er CTL-1601 laser].
Topics: Adolescent; Adult; Aged; Dental Anxiety; Dental Caries; Dental Cavity Preparation; Dental Restoration, Permanent; Female; Glutamic Acid; Humans; Lasers, Solid-State; Leucine; Lysine; Male; Middle Aged; Toothache | 2007 |
Verification of the intermolecular parallel beta-sheet in E22K-Abeta42 aggregates by solid-state NMR using rotational resonance: implications for the supramolecular arrangement of the toxic conformer of Abeta42.
Topics: Amyloid beta-Peptides; Glutamic Acid; Lysine; Microscopy, Electron, Transmission; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Protein Structure, Secondary | 2008 |
Atypical presentation of Creutzfeldt-Jakob disease: the first Italian case associated with E196K mutation in the PRNP gene.
Topics: Aged; Creutzfeldt-Jakob Syndrome; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Italy; Lysine; Magnetic Resonance Imaging; Prion Proteins; Prions | 2008 |
Engineering of a glycerol utilization pathway for amino acid production by Corynebacterium glutamicum.
Topics: Biomass; Cloning, Molecular; Corynebacterium glutamicum; Escherichia coli; Escherichia coli Proteins; Gene Expression; Glutamic Acid; Glycerol; Lysine; Metabolic Networks and Pathways; Plasmids; Recombinant Proteins | 2008 |
Stimuli-responsive zwitterionic block copolypeptides: poly(N-isopropylacrylamide)-block-poly(lysine-co-glutamic acid).
Topics: Acrylic Resins; Biocompatible Materials; Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Light; Lysine; Magnetic Resonance Spectroscopy; Materials Testing; Molecular Conformation; Peptides; Polymers; Scattering, Radiation; Spectrophotometry, Ultraviolet; Temperature | 2008 |
Identification of four novel types of in vitro protein modifications.
Topics: Algorithms; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Chromatography, High Pressure Liquid; Cysteine; Glutamic Acid; Glycerol; Lysine; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Protein Processing, Post-Translational; Proteins; Reproducibility of Results; Sequence Alignment; Serum Albumin, Bovine | 2008 |
Dynamic charge interactions create surprising rigidity in the ER/K alpha-helical protein motif.
Topics: Amino Acid Motifs; Arginine; Computer Simulation; Glutamic Acid; Lysine; Models, Molecular; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins | 2008 |
Spinocerebellar ataxia type 28: a novel autosomal dominant cerebellar ataxia characterized by slow progression and ophthalmoparesis.
Topics: Adolescent; Adult; Aged; Base Sequence; Brain; Child; Chromosome Mapping; Chromosomes, Human, Pair 18; Female; Genes, Dominant; Glutamic Acid; Humans; Lysine; Magnetic Resonance Imaging; Male; Middle Aged; Ophthalmoplegia; Pedigree; Phenotype; Point Mutation; Polymorphism, Single Nucleotide; Spinocerebellar Ataxias; Young Adult | 2008 |
Fluorescence of primary dentine after chemomechanical and conventional rotary excavation.
Topics: Analysis of Variance; Dental Caries; Dental Caries Activity Tests; Dental Cavity Preparation; Dental High-Speed Equipment; Dentin; Fluorescence; Glutamic Acid; Hardness; Humans; Leucine; Lysine; Papain; Random Allocation; Statistics, Nonparametric | 2008 |
Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1.
Topics: Amino Acid Sequence; Animals; Astrocytes; Brain; Cell Line, Tumor; Cerebral Cortex; Down-Regulation; Endocytosis; Excitatory Amino Acid Transporter 2; Glutamic Acid; Lysine; Mutation; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; Rats; Ubiquitin; Ubiquitination | 2008 |
Ubiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosis.
Topics: Adenosine Triphosphatases; Amino Acid Motifs; Bacterial Proteins; Glutamic Acid; Glutamine; Glycine; Lysine; Mass Spectrometry; Molecular Sequence Data; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Ubiquitination; Ubiquitins | 2008 |
The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.
Topics: Actin-Related Protein 2-3 Complex; Actins; Alleles; Amino Acid Substitution; Animals; Cell Movement; Cell Shape; Female; Glutamic Acid; Humans; Lysine; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Microfilament Proteins; Mutation; Severe Combined Immunodeficiency; T-Lymphocytes; Thymus Gland | 2008 |
The inhibitory effects of DL-alanine, L-glutamic acid, L-lysine, and L-histidine on the activity of intestinal, bone, and kidney phosphatases.
Topics: Alanine; Amino Acids; Bone and Bones; Dietary Proteins; Glutamic Acid; Histidine; Humans; Kidney; Lysine; Phosphoric Monoester Hydrolases | 1948 |
K469E polymorphism of the intracellular adhesion molecule 1 gene is associated with proliferative diabetic retinopathy in Caucasians with type 2 diabetes.
Topics: Aged; Alanine; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glycine; Humans; Intercellular Adhesion Molecule-1; Lysine; Male; Middle Aged; Polymorphism, Genetic; Slovenia; White People | 2008 |
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana.
Topics: Apoenzymes; Arabidopsis; Arabidopsis Proteins; Catalysis; Catalytic Domain; Crystallography, X-Ray; Diaminopimelic Acid; Glutamic Acid; Lysine; Models, Molecular; Mutant Proteins; Oxidation-Reduction; Protein Structure, Secondary; Pyridoxal Phosphate; Static Electricity; Substrate Specificity | 2008 |
Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain.
Topics: 3T3 Cells; Animals; Cattle; Cell Membrane; Cell Survival; Glutamic Acid; Humans; Kinetics; Lysine; Mice; Microscopy, Fluorescence; Mutation; Neoplasms; Oncogenes; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Substrate Specificity | 2008 |
New insights into the mechanism of enzymatic chlorination of tryptophan.
Topics: Amino Acid Substitution; Bacterial Proteins; Catalysis; Catalytic Domain; Chlorine; Glutamic Acid; Halogenation; Lysine; Mutation; Oxidoreductases; Protein Structure, Secondary; Pseudomonas fluorescens; Tryptophan | 2008 |
Two novel Jk(null) alleles derived from 222C>A in Exon 5 and 896G>A in Exon 9 of the JK gene.
Topics: 5' Untranslated Regions; Alleles; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; DNA; Exons; Glutamic Acid; Heterozygote; Humans; Introns; Kidd Blood-Group System; Lysine; Molecular Sequence Data; Mutation; Mutation, Missense; Polymerase Chain Reaction; Sequence Analysis, DNA; Valine | 2009 |
[Effect of Carisolv on root canal cleanness in chemomechanical preparation].
Topics: Dental Pulp Cavity; Disinfectants; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Root Canal Irrigants; Root Canal Preparation; Root Canal Therapy; Smear Layer; Sodium Hypochlorite | 2008 |
Two new mutations in the keratin 4 gene causing oral white sponge nevus in Chinese family.
Topics: Adenine; Adult; China; Epithelial Cells; Exons; Female; Glutamic Acid; Guanine; Hamartoma; Humans; Keratin-13; Keratin-4; Lysine; Mouth Diseases; Mutation; Mutation, Missense; Pedigree; RNA, Untranslated | 2009 |
Phenotypic heterogeneity of Streptococcus mutans in dentin.
Topics: Adaptation, Physiological; Child; Colony Count, Microbial; Dental Caries; Dental Cavity Preparation; Dental Restoration, Temporary; Dentin; Follow-Up Studies; Genetic Heterogeneity; Glass Ionomer Cements; Glutamic Acid; Humans; Leucine; Lysine; Molar; Phenotype; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Streptococcus mutans; Tooth, Deciduous | 2008 |
Glutamatergic nonpyramidal neurons from neocortical layer VI and their comparison with pyramidal and spiny stellate neurons.
Topics: Animals; Animals, Newborn; Cholecystokinin; Electric Stimulation; Gene Expression; Glutamate Decarboxylase; Glutamic Acid; In Vitro Techniques; Lysine; Membrane Potentials; Neocortex; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; RNA, Messenger; Vesicular Glutamate Transport Protein 1 | 2009 |
Probing the catalytic triad of an archaeal RNA splicing endonuclease.
Topics: Binding Sites; Catalysis; DNA Primers; Escherichia coli; Evolution, Molecular; Glutamic Acid; Introns; Lysine; Molecular Conformation; Mutation; Protein Binding; Protein Structure, Tertiary; RNA; RNA, Archaeal; Thermotoga maritima | 2008 |
Evaluation of channel function after alteration of amino acid residues at the pore center of KCNQ1 channel.
Topics: Amino Acid Substitution; Animals; Chlorocebus aethiops; COS Cells; Glutamic Acid; Humans; Isoleucine; KCNQ1 Potassium Channel; Lysine; Mutation; Porosity; Static Electricity | 2009 |
Evaluation of the number of ionogenic groups of inulinase by acid-base titration.
Topics: Asparagine; Aspergillus; Fungal Proteins; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Lysine; Protein Denaturation; Serine; Tyrosine | 2008 |
HU participates in expression of a specific set of genes required for growth and survival at acidic pH in Escherichia coli.
Topics: Acids; Amino Acid Transport Systems; Anti-Bacterial Agents; Antiporters; Carboxy-Lyases; Carrier Proteins; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Gene Expression Profiling; Glutamic Acid; Lysine; Microbial Viability; Stress, Physiological; Transcription Factors | 2009 |
Phytates reduce uptake of leucine and glutamate but not lysine and glucose from the intestinal lumen of chickens: short communication.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Glucose; Glutamic Acid; Intestinal Mucosa; Leucine; Lysine; Phytic Acid | 2008 |
Design of a heterotetrameric coiled coil.
Topics: Anilino Naphthalenesulfonates; Circular Dichroism; Disulfides; Fluorescent Dyes; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Models, Molecular; Peptides; Protein Denaturation; Protein Engineering; Protein Folding; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Proteins; Sodium Chloride; Static Electricity; Thermodynamics; Ultracentrifugation | 2009 |
The effects of E23K polymorphism in Kir6.2 subunit on insulin sensitivity in skeletal muscle cells by long-chain fatty acyl CoA.
Topics: Acyl Coenzyme A; Animals; Cell Line; Glutamic Acid; Humans; Insulin; Insulin Resistance; Lysine; Muscle, Skeletal; Polymorphism, Genetic; Potassium Channels, Inwardly Rectifying; Rats | 2009 |
Cell type-specific development of NMDA receptors in the interneurons of rat prefrontal cortex.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Cell Differentiation; Cell Shape; Dendrites; Epigenesis, Genetic; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; Interneurons; Lysine; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Staining and Labeling; Synaptic Transmission | 2009 |
A computational approach to correct arginine-to-proline conversion in quantitative proteomics.
Topics: Animals; Arginine; Cells, Cultured; Computational Biology; Glutamic Acid; Internet; Isotope Labeling; Lysine; Mass Spectrometry; Neurons; Nitrogen Isotopes; PC12 Cells; Peptide Fragments; Proline; Proteins; Proteomics; Rats; Rats, Sprague-Dawley; Software; Tandem Mass Spectrometry | 2009 |
Introducing chemical functionality in Fmoc-peptide gels for cell culture.
Topics: 3T3 Cells; Animals; Biocompatible Materials; Cattle; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Chondrocytes; Cytoskeleton; Dermis; DNA; Elastic Modulus; Elasticity; Fibroblasts; Fluorenes; Gene Transfer Techniques; Glutamic Acid; Humans; Hydrogels; Hydrogen Bonding; Hydrogen-Ion Concentration; Lactate Dehydrogenases; Lysine; Mice; Nanostructures; Peptides; Plasmids; Protein Structure, Secondary; Serine; Static Electricity; Tissue Scaffolds; Viscosity | 2009 |
Incorporating structural characteristics for identification of protein methylation sites.
Topics: Arginine; Asparagine; Binding Sites; Computer Simulation; Glutamic Acid; Lysine; Methylation; Protein Conformation; Proteins; Surface Properties | 2009 |
Characterization of salt bridges to lysines in the protein G B1 domain.
Topics: Aspartic Acid; Bacterial Proteins; Deuterium; Escherichia coli; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Nerve Tissue Proteins; Nuclear Magnetic Resonance, Biomolecular; Protein Structure, Tertiary; Quantum Theory; Salts; Streptococcus | 2009 |
Crystal structure of Bacillus cereus D-alanyl carrier protein ligase (DltA) in complex with ATP.
Topics: Adenosine Triphosphate; Arginine; Bacillus cereus; Bacterial Proteins; Carbon-Oxygen Ligases; Catalysis; Glutamic Acid; Lysine; Molecular Structure; Protein Binding; Protein Conformation | 2009 |
Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils.
Topics: Amyloid; Amyloid beta-Peptides; Amyloid Neuropathies, Familial; Aspartic Acid; Benzothiazoles; Glutamic Acid; Humans; Kinetics; Leucine; Lysine; Microscopy, Electron, Transmission; Models, Molecular; Mutation, Missense; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phenylalanine; Protein Structure, Secondary; Spectrometry, Fluorescence; Thiazoles; X-Ray Diffraction | 2009 |
Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites.
Topics: Catalytic Domain; Cell Cycle Proteins; DNA; Glutamic Acid; Humans; Lysine; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Multimerization; Protein Structure, Tertiary | 2009 |
Structure-activity relationships in Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease.
Topics: Amino Acid Sequence; Arginine; Glutamic Acid; Histidine; Killer Factors, Yeast; Kluyveromyces; Lysine; Molecular Sequence Data; Recombinant Proteins; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2009 |
A novel limb in the osmoregulatory network of Methanosarcina mazei Gö1: N(epsilon)-acetyl-beta-lysine can be substituted by glutamate and alanine.
Topics: Acetyltransferases; Alanine; Betaine; Gene Deletion; Genes, Archaeal; Glutamic Acid; Intramolecular Transferases; Lysine; Magnetic Resonance Spectroscopy; Methanosarcina; Saline Solution, Hypertonic; Water-Electrolyte Balance | 2009 |
A novel HLA-DRB1 allele, DRB*1611, is identified in two Taiwanese individuals.
Topics: Alleles; Amino Acid Substitution; Blood Donors; Cloning, Molecular; Fetal Blood; Glutamic Acid; Histocompatibility Testing; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Infant, Newborn; Lysine; Sequence Analysis, DNA; Taiwan | 2009 |
Copolypeptide-doped polyaniline nanofibers for electrochemical detection of ultratrace trinitrotoluene.
Topics: Aniline Compounds; Electrochemical Techniques; Electrodes; Glutamic Acid; Lysine; Nanostructures; Oxidation-Reduction; Peptides; Trinitrotoluene | 2009 |
TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices.
Topics: Animals; Astrocytes; Barium; Biophysical Phenomena; Biophysics; Cesium; CHO Cells; Cricetinae; Cricetulus; Electric Conductivity; Electric Stimulation; Excitatory Amino Acid Transporter 1; Glial Fibrillary Acidic Protein; Glutamic Acid; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Ion Channel Gating; Lysine; Membrane Potentials; Mutation; Oocytes; Patch-Clamp Techniques; Potassium; Potassium Channels, Tandem Pore Domain; Rats; Transfection; Xenopus | 2009 |
Creutzfeldt-Jakob disease with E200K PRNP mutation: a case report and revision of the literature.
Topics: Creutzfeldt-Jakob Syndrome; DNA Mutational Analysis; Female; Glutamic Acid; Humans; Lysine; Middle Aged; Mutation; Prion Proteins; Prions | 2009 |
TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea.
Topics: Chorea; DNA Mutational Analysis; DNA-Binding Proteins; Family Health; Female; Frontotemporal Dementia; Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neuropsychological Tests; Supranuclear Palsy, Progressive; Tomography Scanners, X-Ray Computed | 2009 |
Strategy for identification by mass spectrometry of a new human hemoglobin variant with two mutations in Cis in the beta-globin chain: Hb S-Clichy [beta6(A3)Glu-->Val; beta8(A5)Lys-->Thr].
Topics: Anemia, Sickle Cell; beta-Globins; Chromatography, Liquid; Female; Glutamic Acid; Hemoglobin, Sickle; Hemoglobins, Abnormal; Humans; Lysine; Mass Spectrometry; Middle Aged; Mutation; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Valine | 2009 |
No involvement of the NOD1 polymorphism Glu266Lys in Japanese leprosy patients.
Topics: Adult; Aged; Asian People; Female; Genotype; Glutamic Acid; Humans; Japan; Leprosy; Lysine; Male; Nod1 Signaling Adaptor Protein; Polymorphism, Single Nucleotide | 2009 |
PKC phosphorylation of titin's PEVK element: a novel and conserved pathway for modulating myocardial stiffness.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Connectin; Elasticity; Glutamic Acid; Heart Ventricles; Humans; Lysine; Male; Mice; Molecular Sequence Data; Muscle Proteins; Muscle Tonus; Mutagenesis, Site-Directed; Mutation; Myocardial Contraction; Myocardium; Peptide Fragments; Phosphorylation; Proline; Protein Kinase C-alpha; Protein Kinases; Protein Phosphatase 1; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Signal Transduction; Swine; Tandem Mass Spectrometry; Time Factors; Valine | 2009 |
Titin phosphorylation: myocardial passive stiffness regulated by the intracellular giant.
Topics: Amino Acid Motifs; Connectin; Elasticity; Glutamic Acid; Heart Ventricles; Humans; Lysine; Male; Muscle Proteins; Muscle Tonus; Myocardial Contraction; Myocardium; Phosphorylation; Proline; Protein Kinase C-alpha; Protein Kinases; Protein Phosphatase 1; Protein Processing, Post-Translational; Recombinant Proteins; Signal Transduction; Valine | 2009 |
Arginine and lysine decarboxylases and the acid tolerance response of Salmonella Typhimurium.
Topics: Adaptation, Physiological; Arginine; Carboxy-Lyases; Consumer Product Safety; Gene Expression Regulation, Bacterial; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Salmonella Food Poisoning; Salmonella typhimurium | 2010 |
A mutation in the beta-myosin rod associated with hypertrophic cardiomyopathy has an unexpected molecular phenotype.
Topics: Amino Acid Substitution; Cardiomyopathy, Hypertrophic; Glutamic Acid; Humans; Lysine; Mutation; Phenotype; Protein Stability; Protein Structure, Secondary; Thermodynamics; Ventricular Myosins | 2010 |
Are density functional theory predictions of the Raman spectra accurate enough to distinguish conformational transitions during amyloid formation?
Topics: Amyloid; Glutamic Acid; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Structure; Oligopeptides; Peptides; Protein Conformation; Protein Structure, Secondary; Spectrum Analysis, Raman; Water | 2010 |
BMAA neurotoxicity in Drosophila.
Topics: Alanine; Amino Acids, Diamino; Analysis of Variance; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cyanobacteria Toxins; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila melanogaster; Female; Glutamic Acid; Leucine; Longevity; Lysine; Male; Neurotoxicity Syndromes; Neurotoxins | 2009 |
Partitioning of acidic, basic and neutral amino acids into imidazolium-based ionic liquids.
Topics: Alanine; Glutamic Acid; Hydrogen-Ion Concentration; Imidazoles; Ionic Liquids; Lysine; Molecular Structure; Solvents; Water | 2010 |
[Fluorescence analysis of trace glucose using glucose oxidase and horseradish peroxidase].
Topics: Cystine; Fluorescence; Glucose; Glucose Oxidase; Glutamic Acid; Horseradish Peroxidase; Hydrogen Peroxide; Lysine; Oxidation-Reduction; Rhodamines; Spectrometry, Fluorescence; Tyrosine | 2009 |
Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Lysine; Mice; Molecular Conformation; Mutation; Phosphorylation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Ribosomal Protein S6 Kinases, 90-kDa | 2009 |
Differential phospholipid binding of alpha-synuclein variants implicated in Parkinson's disease revealed by solution NMR spectroscopy.
Topics: Alanine; alpha-Synuclein; Genetic Variation; Glutamic Acid; Humans; Lysine; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Parkinson Disease; Peptide Fragments; Phospholipids; Proline; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Solutions; Threonine | 2010 |
Interactions at the 2 and 5 positions of 5-phosphoribosyl pyrophosphate are essential in Salmonella typhimurium quinolinate phosphoribosyltransferase.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Catalytic Domain; Enzyme Stability; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Protein Binding; Salmonella typhimurium; Substrate Specificity | 2010 |
Rhythmic pupillary oscillation in Creutzfeldt-Jakob disease associated with the Glu/Lys mutation of prion protein codon 200.
Topics: Aged; Creutzfeldt-Jakob Syndrome; Female; Glutamic Acid; Humans; Lysine; Magnetic Resonance Imaging; Male; Mutation; Periodicity; Prions; Pupil Disorders | 2010 |
Glia-dependent switch of kainate receptor presynaptic action.
Topics: Animals; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Kainic Acid; Lysine; Neuroglia; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Kainic Acid; Suprachiasmatic Nucleus | 2010 |
Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Exonucleases; Female; Glutamic Acid; Histidine; Histidine Kinase; Humans; Lung Neoplasms; Lysine; Melanoma, Experimental; Mice; Mice, Nude; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation, Missense; NM23 Nucleoside Diphosphate Kinases; Protein Conformation; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2011 |
Conformational consequences of ionization of Lys, Asp, and Glu buried at position 66 in staphylococcal nuclease.
Topics: Aspartic Acid; Circular Dichroism; Crystallography, X-Ray; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Micrococcal Nuclease; Models, Molecular; Protein Conformation; Thermodynamics | 2010 |
Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for L-lysine production from methanol at 50 degrees C.
Topics: Bacillus; Bacterial Proteins; Cloning, Molecular; Fermentation; Glutamic Acid; Homoserine Dehydrogenase; Hot Temperature; Lysine; Methanol; Methionine; Molecular Sequence Data; Mutation; Pyruvate Carboxylase; Threonine | 2010 |
Avt5p is required for vacuolar uptake of amino acids in the fission yeast Schizosaccharomyces pombe.
Topics: Amino Acid Transport Systems; Amino Acids; Arginine; Biological Transport; Glutamic Acid; Histidine; Lysine; Membrane Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Tyrosine; Vacuoles; Vesicular Transport Proteins | 2010 |
The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: Relation with endothelial ADMA levels.
Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Arginine; China; Coronary Artery Disease; Endothelium, Vascular; Female; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors | 2010 |
Glutamate 90 at the luminal ion gate of sarcoplasmic reticulum Ca2+-ATPase is critical for Ca(2+) binding on both sides of the membrane.
Topics: Animals; Binding Sites; Calcium; Databases, Protein; Glutamic Acid; Intracellular Membranes; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Conformation; Rabbits; Recombinant Proteins; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine | 2010 |
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
Topics: Acid-Base Equilibrium; Alanine; Amino Acid Substitution; Binding, Competitive; Catalysis; Catalytic Domain; Glutamic Acid; Glutamine; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NAD; Recombinant Proteins; Saccharomyces cerevisiae; Saccharopine Dehydrogenases | 2010 |
Tetra-glutamic acid residues adjacent to Lys248 in HMG-CoA reductase are critical for the ubiquitination mediated by gp78 and UBE2G2.
Topics: Acyl Coenzyme A; Animals; CHO Cells; Cricetinae; Cricetulus; Glutamic Acid; Humans; Hydroxymethylglutaryl CoA Reductases; Lysine; Receptors, Autocrine Motility Factor; Receptors, Cytokine; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination | 2010 |
Requirements for catalysis in the Cre recombinase active site.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Biocatalysis; Catalytic Domain; Glutamic Acid; Histidine; Integrases; Lysine; Models, Molecular; Molecular Sequence Data; Recombination, Genetic; Tryptophan; Tyrosine; Vanadates | 2010 |
Hydroxyapatite as a key biomaterial: quantum-mechanical simulation of its surfaces in interaction with biomolecules.
Topics: Adsorption; Biocompatible Materials; Durapatite; Glutamic Acid; Glycine; Lysine; Quantum Theory; Surface Properties; Thermodynamics | 2010 |
Electron capture dissociation of highly charged proteolytic peptides from Lys N, Lys C and Glu C digestion.
Topics: Chymotrypsin; Glutamic Acid; Lysine; Peptides; Tandem Mass Spectrometry; Trypsin | 2010 |
The contribution of interchain salt bridges to triple-helical stability in collagen.
Topics: Aspartic Acid; Collagen; Glutamic Acid; Lysine; Molecular Dynamics Simulation; Peptides; Protein Conformation; Protein Stability; Protein Structure, Secondary; Thermodynamics; Time Factors | 2010 |
Cardiomyopathy in a Japanese family with the Glu61Lys transthyretin variant: a new phenotype.
Topics: Aged; Cardiomyopathies; Female; Glutamic Acid; Humans; Japan; Lysine; Male; Prealbumin | 2009 |
Substitution of lysine with glutamic acid at position 193 in bovine CYP11A1 significantly affects protein oligomerization and solubility but not enzymatic activity.
Topics: Amino Acid Substitution; Animals; Biocatalysis; Biosensing Techniques; Catalytic Domain; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Mutation; Protein Multimerization; Protein Structure, Tertiary; Solubility; Substrate Specificity | 2011 |
Polymorphisms of the prion protein gene (PRNP) in a Serbian population.
Topics: Amino Acid Substitution; Female; Genetic Predisposition to Disease; Genetic Testing; Glutamic Acid; Humans; Lysine; Male; Mutagenesis, Insertional; Oligopeptides; Polymorphism, Genetic; Prion Diseases; Prion Proteins; Prions; Repetitive Sequences, Amino Acid; Sequence Deletion; Serbia | 2010 |
Genetic Creutzfeldt-Jakob disease associated with the E200K mutation: characterization of a complex proteinopathy.
Topics: Amino Acid Substitution; Creutzfeldt-Jakob Syndrome; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Prion Proteins; Prions | 2011 |
Production of the amino acids l-glutamate, l-lysine, l-ornithine and l-arginine from arabinose by recombinant Corynebacterium glutamicum.
Topics: Arabinose; Arginine; Corynebacterium glutamicum; Escherichia coli; Glucose; Glutamic Acid; Industrial Microbiology; Lysine; Operon; Ornithine | 2011 |
Helicity of short E-R/K peptides.
Topics: Amino Acid Sequence; Arginine; Circular Dichroism; Glutamic Acid; Lysine; Oligopeptides; Protein Structure, Secondary | 2010 |
Inhibition of Streptococcus mutans adherence and biofilm formation using analogues of the SspB peptide.
Topics: Adhesins, Bacterial; Amino Acid Sequence; Aspartic Acid; Bacterial Adhesion; Binding, Competitive; Biofilms; Biosensing Techniques; Dental Pellicle; Glutamic Acid; Humans; Lysine; Peptides; Protein Binding; Protein Structure, Secondary; Salivary Proteins and Peptides; Streptococcus gordonii; Streptococcus mutans | 2010 |
Hereditary cerebral hemorrhage with amyloidosis associated with the E693K mutation of APP.
Topics: Aged; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis, Familial; Apolipoprotein E4; Cerebral Hemorrhage; Family Health; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Glutamic Acid; Humans; Italy; Lysine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Peptide Fragments | 2010 |
Peptidic HIV integrase inhibitors derived from HIV gene products: structure-activity relationship studies.
Topics: Amino Acid Sequence; Cell Line; Circular Dichroism; Glutamic Acid; HIV Integrase Inhibitors; Humans; Lysine; Molecular Sequence Data; Peptides; Structure-Activity Relationship; vpr Gene Products, Human Immunodeficiency Virus | 2010 |
An atypical phenotype of CJD associated with the E200K mutation in the prion protein gene.
Topics: Amino Acid Substitution; Creutzfeldt-Jakob Syndrome; Female; Genetic Heterogeneity; Glutamic Acid; Humans; Lysine; Middle Aged; Phenotype; Point Mutation; Prion Proteins; Prions | 2010 |
Deceleration of the E1P-E2P transition and ion transport by mutation of potentially salt bridge-forming residues Lys-791 and Glu-820 in gastric H+/K+-ATPase.
Topics: Amino Acid Sequence; Animals; Cell Membrane; Electrophysiology; Gastric Mucosa; Glutamic Acid; H(+)-K(+)-Exchanging ATPase; Imidazoles; Lysine; Molecular Sequence Data; Mutation; Oocytes; Protein Conformation; Rats; Rhodamines; Salts; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Xenopus | 2010 |
Characterization of a mutation commonly associated with persistent stuttering: evidence for a founder mutation.
Topics: Amino Acid Substitution; Chromosome Mapping; Family Characteristics; Founder Effect; Genome-Wide Association Study; Glutamic Acid; Humans; Lysine; Mutation; Phylogeny; Polymorphism, Single Nucleotide; Stuttering; Transferases (Other Substituted Phosphate Groups) | 2011 |
ENPP1/PC-1 K121Q and other predictors of posttransplant diabetes.
Topics: Adult; Age Factors; Amino Acid Substitution; Biomarkers; Diabetes Mellitus; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Prognosis; Pyrophosphatases; Racial Groups; Transplantation | 2011 |
The ENPP1 K121Q polymorphism is not associated with type 2 diabetes or obesity in the Chinese Han population.
Topics: Aged; Amino Acid Substitution; Asian People; Diabetes Mellitus, Type 2; Female; Genetics, Population; Genome-Wide Association Study; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Obesity; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Pyrophosphatases | 2011 |
Structural origins of high apparent dielectric constants experienced by ionizable groups in the hydrophobic core of a protein.
Topics: Aspartic Acid; Glutamic Acid; Hydrogen; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Lysine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Models, Molecular; Protein Conformation; Static Electricity; Thermodynamics | 2011 |
Synthesis of stereoarray isotope labeled (SAIL) lysine via the "head-to-tail" conversion of SAIL glutamic acid.
Topics: Glutamic Acid; Lysine; Molecular Structure; Stereoisomerism | 2011 |
The ENPP1 K121Q polymorphism is not associated with type 2 diabetes and related metabolic traits in an Iranian population.
Topics: Adult; Aged; Amino Acid Substitution; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genetics, Population; Genotype; Glutamic Acid; Humans; Insulin Resistance; Iran; Lysine; Male; Metabolic Diseases; Middle Aged; Phosphoric Diester Hydrolases; Polymorphism, Single Nucleotide; Pyrophosphatases; Young Adult | 2011 |
Exploring the use of dimethylsulfate for in vivo proteome footprinting.
Topics: Amino Acid Sequence; Animals; Chromatin; Glutamic Acid; HeLa Cells; Histidine; Histones; Humans; Lysine; Methylation; Molecular Sequence Data; Protein Folding; Protein Multimerization; Proteome; Proteomics; Sulfuric Acid Esters; Xenopus | 2011 |
Cations but not anions regulate the responsiveness of kainate receptors.
Topics: Animals; Anions; Biophysics; Cations; Cell Line, Transformed; Chromates; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; GluK2 Kainate Receptor; Glutamic Acid; Green Fluorescent Proteins; Humans; Kainic Acid; Lysine; Membrane Potentials; Models, Molecular; Mutation; Nitrates; Patch-Clamp Techniques; Protein Binding; Rats; Receptors, Kainic Acid; Sodium Iodide; Transfection | 2011 |
Morphological and microtensile bond strength evaluation of three adhesive systems to caries-affected human dentine with chemomechanical caries removal.
Topics: Analysis of Variance; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Etching; Dental Stress Analysis; Dentin; Dentin-Bonding Agents; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Methacrylates; Polymethacrylic Acids; Resin Cements; Smear Layer; Tensile Strength | 2011 |
Does DIAGNOdent provide a reliable caries-removal endpoint?
Topics: Ceramics; Coloring Agents; Dental Caries; Dental Cavity Preparation; Dental Pulp Cavity; Dentin; Durapatite; Fluorescence; Glutamic Acid; Hardness; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lasers; Leucine; Lysine; Minerals; Pepsin A; Software; Tungsten Compounds; Ultrasonics; X-Ray Microtomography | 2011 |
Amino acids improve acid tolerance and internal pH maintenance in Bacillus cereus ATCC14579 strain.
Topics: Adaptation, Physiological; Amino Acids; Arginine; Bacillus cereus; Carboxy-Lyases; Consumer Product Safety; Culture Media; Food Contamination; Food Microbiology; Glutamic Acid; Hydrogen-Ion Concentration; Lysine | 2011 |
Scanning electron microscopy in vitro study on the effect of Carisolv application on periodontally diseased root surfaces.
Topics: Dental Calculus; Dental Plaque; Dental Scaling; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Smear Layer; Tooth Root; Treatment Failure | 2011 |
A novel HLA-DRB4 allele, DRB4*01:08, identified by sequence-based typing.
Topics: Alleles; Base Sequence; Codon; Exons; Glutamic Acid; HLA-DRB4 Chains; Humans; Japan; Lysine; Molecular Sequence Data; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Takayasu Arteritis | 2011 |
De novo design of supercharged, unfolded protein polymers, and their assembly into supramolecular aggregates.
Topics: Animals; Cell Survival; Drug Carriers; Elastin; Escherichia coli; Gene Expression; Glutamic Acid; Lysine; Mice; Molecular Structure; NIH 3T3 Cells; Oligopeptides; Protein Unfolding; Recombinant Proteins; Static Electricity; Stereoisomerism | 2011 |
Development of intravascular contrast agents for MRI using gadolinium chelates.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Contrast Media; Coordination Complexes; Gadolinium; Glutamic Acid; Humans; Lysine; Magnetic Resonance Imaging; Male; Organometallic Compounds; Rats; Rats, Wistar | 2011 |
ATP requirement for acidic resistance in Escherichia coli.
Topics: Acids; Adenosine Triphosphate; Arginine; DNA Damage; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genome, Bacterial; Glutamic Acid; Homeostasis; Hydrogen-Ion Concentration; Lysine | 2011 |
Micro-tensile bond strength and interfacial characterization of an adhesive bonded to dentin prepared by contemporary caries-excavation techniques.
Topics: Azo Compounds; Collagen; Coloring Agents; Composite Resins; Crowns; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dentin; Dentin-Bonding Agents; Eosine Yellowish-(YS); Equipment Design; Glutamic Acid; Humans; Lasers, Solid-State; Leucine; Lysine; Materials Testing; Methyl Green; Microscopy, Electron, Scanning; Resin Cements; Silicon Dioxide; Stress, Mechanical; Surface Properties; Temperature; Tensile Strength; Time Factors; Tungsten Compounds; Water; Zirconium | 2011 |
Simple physics-based analytical formulas for the potentials of mean force of the interaction of amino-acid side chains in water. VI. Oppositely charged side chains.
Topics: Amino Acids; Arginine; Aspartic Acid; Glutamic Acid; Lysine; Molecular Dynamics Simulation; Proteins; Water | 2011 |
Simple physics-based analytical formulas for the potentials of mean force of the interaction of amino-acid side chains in water. V. Like-charged side chains.
Topics: Amino Acids; Arginine; Aspartic Acid; Glutamic Acid; Lysine; Models, Theoretical; Molecular Dynamics Simulation; Protein Folding; Proteins; Water | 2011 |
Reduced cortical thickness is associated with the glutamatergic regulatory gene risk variant DAOA Arg30Lys in schizophrenia.
Topics: Adult; Arginine; Carrier Proteins; Cerebral Cortex; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genetic Variation; Glutamic Acid; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Male; Polymorphism, Genetic; Schizophrenia; Young Adult | 2011 |
Nemaline myopathy and non-fatal hypertrophic cardiomyopathy caused by a novel ACTA1 E239K mutation.
Topics: Actins; Amino Acid Sequence; Cardiomyopathy, Hypertrophic; Glutamic Acid; Humans; Lysine; Male; Molecular Sequence Data; Muscle, Skeletal; Myopathies, Nemaline; Point Mutation; Young Adult | 2011 |
Pacemaker neurons within newborn spinal pain circuits.
Topics: Action Potentials; Age Factors; Amino Acids; Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Calcium; Calcium Channel Blockers; Chelating Agents; Chi-Square Distribution; Egtazic Acid; Excitatory Amino Acid Antagonists; Flufenamic Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; In Vitro Techniques; Lysine; Male; Nerve Net; Neural Pathways; Neurons; omega-Conotoxin GVIA; Patch-Clamp Techniques; Periaqueductal Gray; Periodicity; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spinal Cord; Statistics, Nonparametric; Tetraethylammonium; Tetrodotoxin; Vesicular Glutamate Transport Protein 2 | 2011 |
Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P₂ phosphatase FIG4.
Topics: Adult; Australia; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Exons; Family Health; Female; Flavoproteins; Foot Deformities; Genotype; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Models, Molecular; Muscle Weakness; Mutation; Neural Conduction; Phenotype; Phosphoric Monoester Hydrolases; Sural Nerve | 2011 |
Ubiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5.
Topics: Amino Acid Substitution; Animals; Cell Line; Cell Line, Tumor; Cyclin-Dependent Kinase 5; DNA-(Apurinic or Apyrimidinic Site) Lyase; Glutamic Acid; Humans; Lysine; Mice; Proto-Oncogene Proteins c-mdm2; Threonine; Ubiquitination | 2011 |
The effect of the dilated cardiomyopathy-causing Glu40Lys TPM1 mutation on actin-myosin interactions during the ATPase cycle.
Topics: Actins; Adenosine Triphosphatases; Cardiomyopathy, Dilated; Glutamic Acid; Humans; Lysine; Myosins; Tropomyosin | 2011 |
Conformational flexibility, binding energy, role of salt bridge and alanine-mutagenesis for c-Abl kinase complex.
Topics: Alanine; Benzamides; Binding Sites; Glutamic Acid; Humans; Hydrogen Bonding; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Ligands; Lysine; Molecular Dynamics Simulation; Mutagenesis; Piperazines; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Salts; Thermodynamics | 2012 |
The EEG in E200K familial CJD: relation to MRI patterns.
Topics: Aged; Brain; Brain Mapping; Creutzfeldt-Jakob Syndrome; Diffusion Magnetic Resonance Imaging; Electroencephalography; Female; Glutamic Acid; Humans; Lysine; Magnetic Resonance Imaging; Male; Middle Aged; Prions; Retrospective Studies | 2012 |
Mutation of OsALDH7 causes a yellow-colored endosperm associated with accumulation of oryzamutaic acid A in rice.
Topics: Acids; Aldehyde Dehydrogenase; Alkaloids; Amino Acid Sequence; Chromosome Mapping; Chromosomes, Plant; Cloning, Molecular; Endosperm; Gene Expression Regulation, Plant; Genes, Plant; Genetic Vectors; Glutamic Acid; Lysine; Molecular Sequence Data; Mutation; Oryza; Pigmentation; Pigments, Biological; Transformation, Genetic; Yeasts | 2012 |
Durable molecular response despite F317L and E255K mutations: Successful treatment of chronic myeloid leukemia with sequential imatinib, nilotinib and dasatinib.
Topics: Adult; Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Pharmacological; Biomarkers, Tumor; Dasatinib; Female; Fusion Proteins, bcr-abl; Glutamic Acid; Humans; Imatinib Mesylate; Leucine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lysine; Mutation, Missense; Phenylalanine; Piperazines; Polymorphism, Single Nucleotide; Pyrimidines; Remission Induction; Thiazoles; Time Factors; Treatment Outcome | 2012 |
Ivy/neurogliaform interneurons coordinate activity in the neurogenic niche.
Topics: Action Potentials; Animals; Animals, Newborn; Bacterial Proteins; Biophysical Phenomena; Cell Adhesion Molecules, Neuronal; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Matrix Proteins; GABA Antagonists; Glutamic Acid; Green Fluorescent Proteins; Interneurons; Iontophoresis; Luminescent Proteins; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Neurological; Nerve Net; Nerve Tissue Proteins; Neural Inhibition; Neurogenesis; Neuropeptide Y; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Picrotoxin; Pro-Opiomelanocortin; Quinoxalines; Reelin Protein; Serine Endopeptidases; Stem Cell Niche; Synaptic Potentials; Time Factors; Valine | 2011 |
A QM/MM-based computational investigation on the catalytic mechanism of saccharopine reductase.
Topics: 2-Aminoadipic Acid; Catalysis; Glutamic Acid; Lysine; Magnaporthe; NADP; Saccharopine Dehydrogenases | 2011 |
A large family with MYH9 disorder caused by E1841K mutation suffering from serious kidney and hearing impairment and cataracts.
Topics: Amino Acid Substitution; Cataract; Family Characteristics; Glutamic Acid; Hearing Loss; Humans; Kidney Diseases; Lysine; Male; Middle Aged; Molecular Motor Proteins; Mutation, Missense; Myosin Heavy Chains; Pedigree; Severity of Illness Index | 2012 |
Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population.
Topics: Adult; Areca; Arginine; Arylamine N-Acetyltransferase; Case-Control Studies; Codon; DNA Repair; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Glycine; Heterozygote; Homozygote; Humans; India; Lysine; Male; Methionine; Multifactor Dimensionality Reduction; Oral Submucous Fibrosis; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Tobacco, Smokeless; Tryptophan; X-ray Repair Cross Complementing Protein 1 | 2012 |
Copper is toxic to PrP-ablated mice and exacerbates disease in a mouse model of E200K genetic prion disease.
Topics: Age Factors; Animals; Cells, Cultured; Cerebellum; Chromatography, Affinity; Copper; Copper Sulfate; Creutzfeldt-Jakob Syndrome; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Glutamic Acid; Humans; Imidazoles; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prions; Protein Binding | 2012 |
Amino acid supplementation does not alter whole-body phenylalanine kinetics in Arabian geldings.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Carbon Isotopes; Dietary Supplements; Glutamic Acid; Horses; Kinetics; Leucine; Lysine; Male; Nutritional Requirements; Orchiectomy; Phenylalanine | 2012 |
Intraneuronal immunoreactivity for the prion protein distinguishes a subset of E200K genetic from sporadic Creutzfeldt-Jakob Disease.
Topics: Adaptor Proteins, Signal Transducing; Aged; Amyloid beta-Peptides; Chi-Square Distribution; Creutzfeldt-Jakob Syndrome; DNA-Binding Proteins; Female; Glutamic Acid; Humans; Intranuclear Inclusion Bodies; Lysine; Male; Microscopy, Electron, Transmission; Middle Aged; Mutation; Nerve Tissue Proteins; Neurons; Prions; rab5 GTP-Binding Proteins; Sequestosome-1 Protein; Synucleins; Tubulin | 2012 |
The inner membrane protein, YhiM, is necessary for Escherichia coli (E. coli) survival in acidic conditions.
Topics: Acids; Arginine; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Membrane Proteins; Microbial Viability; Mutation; Stress, Physiological | 2012 |
Association between three genetic polymorphisms of glutathione S-transferase Z1 (GSTZ1) and susceptibility to bipolar disorder.
Topics: Adolescent; Adult; Age Factors; Bipolar Disorder; Chi-Square Distribution; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutathione Transferase; Humans; Linkage Disequilibrium; Logistic Models; Lysine; Male; Middle Aged; Polymorphism, Single Nucleotide; Young Adult | 2012 |
Glu121-Lys319 salt bridge between catalytic and N-terminal domains is pivotal for the activity and stability of Escherichia coli aminopeptidase N.
Topics: Amino Acid Sequence; Aminopeptidases; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Escherichia coli Proteins; Glutamic Acid; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phylogeny; Protein Denaturation; Protein Engineering; Sequence Alignment | 2012 |
Clinical evaluation of caries removal in primary teeth using conventional, chemomechanical and laser technique: an in vivo study.
Topics: Child; Child Behavior; Child, Preschool; Crying; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Efficiency; Glutamic Acid; Humans; Laser Therapy; Lasers, Solid-State; Leucine; Lysine; Pain Measurement; Papain; Time Factors; Tooth, Deciduous; Treatment Outcome | 2012 |
Investigating the parameters affecting the adsorption of amino acids onto AgCl nanoparticles with different surface charges.
Topics: Adsorption; Alanine; Biocompatible Materials; Glutamic Acid; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Lysine; Metal Nanoparticles; Microscopy, Electron, Transmission; Silver Compounds; Solutions; Static Electricity; Surface Properties; Surface-Active Agents; Thermodynamics | 2012 |
Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
Topics: Acid-Base Equilibrium; Base Sequence; Catalytic Domain; DNA Primers; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Saccharopine Dehydrogenases | 2012 |
Mouse adaptation of a sub-genogroup B5 strain of human enterovirus 71 is associated with a novel lysine to glutamic acid substitution at position 244 in protein VP1.
Topics: 5' Untranslated Regions; Adaptation, Physiological; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Capsid Proteins; Cell Line; CHO Cells; Cricetinae; Enterovirus A, Human; Enterovirus Infections; Glutamic Acid; Humans; Lysine; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation, Missense; Open Reading Frames; Virulence | 2012 |
A shift in the salt bridge interaction of residues D620 and E621 mediates the constitutive activation of Jak2-H538Q/K539L.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Catalytic Domain; Chlorocebus aethiops; COS Cells; Enzyme Activation; Gene Expression Regulation; Genes, Reporter; Glutamic Acid; Humans; Janus Kinase 2; Luciferases, Firefly; Lysine; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Signal Transduction; Thermodynamics | 2012 |
Association of KCNJ11 E23K gene polymorphism with hypoglycemia in sulfonylurea-treated type 2 diabetic patients.
Topics: Adult; Aged; Alleles; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Diabetes Mellitus, Type 2; Female; Genotype; Gliclazide; Glutamic Acid; Glycated Hemoglobin; Greece; Humans; Hypoglycemia; Lysine; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Potassium Channels, Inwardly Rectifying; Sulfonylurea Compounds | 2012 |
[Effect of Carisolv on endodontic microleakage].
Topics: Dental Pulp Cavity; Glutamic Acid; Humans; Leucine; Lysine; Random Allocation; Root Canal Irrigants; Root Canal Therapy; Smear Layer; Sodium Hypochlorite | 2012 |
Genome sequence of thermotolerant Bacillus methanolicus: features and regulation related to methylotrophy and production of L-lysine and L-glutamate from methanol.
Topics: Alcohol Oxidoreductases; Bacillus; Base Sequence; Biosynthetic Pathways; DNA Primers; DNA, Complementary; Genome, Bacterial; Glutamic Acid; Lysine; Metabolic Networks and Pathways; Methanol; Microarray Analysis; Molecular Sequence Annotation; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA | 2012 |
E138K and M184I mutations in HIV-1 reverse transcriptase coemerge as a result of APOBEC3 editing in the absence of drug exposure.
Topics: Adenine; Anti-HIV Agents; APOBEC Deaminases; Cytidine Deaminase; Cytosine Deaminase; DNA Mutational Analysis; Drug Resistance, Viral; Female; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Humans; Isoleucine; Lysine; Male; Methionine; Mutation; Nitriles; Organophosphonates; Pyridazines; Pyrimidines; Rilpivirine; Tenofovir; Treatment Failure; Virus Replication | 2012 |
Understanding the drug resistance mechanism of hepatitis C virus NS3/4A to ITMN-191 due to R155K, A156V, D168A/E mutations: a computational study.
Topics: Alanine; Amino Acid Substitution; Antiviral Agents; Arginine; Aspartic Acid; Comprehension; Computational Biology; Cyclopropanes; Drug Resistance, Viral; Glutamic Acid; Hepacivirus; Isoindoles; Lactams; Lactams, Macrocyclic; Lysine; Models, Molecular; Molecular Dynamics Simulation; Mutation, Missense; Proline; Sulfonamides; Valine; Viral Nonstructural Proteins | 2012 |
Cleft lip in oculodentodigital dysplasia suggests novel roles for connexin43.
Topics: Abnormalities, Multiple; Adenine; Animals; Bone Morphogenetic Protein 4; Child, Preschool; Cleft Lip; Connexin 43; Epithelium; Exons; Eye Abnormalities; Fingers; Galactosyltransferases; Glucosyltransferases; Glutamic Acid; Guanine; Heterozygote; Humans; Infant; Introns; Lip; Lysine; Male; Mice; Models, Animal; Polymorphism, Single Nucleotide; Tooth Abnormalities; Transcription Factor AP-2 | 2012 |
Temporal and spatial dynamics of thalamus-evoked activity in the anterior cingulate cortex.
Topics: Algorithms; Animals; Data Interpretation, Statistical; Electric Stimulation; Glutamic Acid; Gyrus Cinguli; In Vitro Techniques; Lysine; Male; Mice; Mice, Inbred C57BL; Naloxone; Narcotic Antagonists; Nerve Net; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Thalamus | 2012 |
X-ray microtomography study to validate the efficacies of caries removal in primary molars by hand excavation and chemo-mechanical technique.
Topics: Dental Caries; Dental Cavity Preparation; Dental Instruments; Dentin; Glutamic Acid; Hardness; Humans; Imaging, Three-Dimensional; Leucine; Lysine; Molar; Tooth, Deciduous; X-Ray Microtomography | 2012 |
Effect of glutamate side chain length on intrahelical glutamate-lysine ion pairing interactions.
Topics: Amino Acid Sequence; Databases, Protein; Drug Design; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Oligopeptides; Protein Structure, Secondary; Thermodynamics | 2012 |
Conductance properties of the inwardly rectifying channel, Kir3.2: molecular and Brownian dynamics study.
Topics: Animals; Bee Venoms; Biophysics; Electric Conductivity; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Ion Channel Gating; Ions; Kinetics; Lysine; Magnesium; Mice; Models, Molecular; Models, Statistical; Molecular Conformation; Mutation; Peptides; Phenylalanine; Protein Binding; Tyrosine | 2013 |
Peptide-based gemini amphiphiles: phase behavior and rheology of wormlike micelles.
Topics: Glutamates; Glutamic Acid; Lysine; Micelles; Peptides; Rheology; Surface-Active Agents; Viscosity | 2012 |
Natural templates for coiled-coil biomaterials from praying mantis egg cases.
Topics: Alanine; Amino Acid Sequence; Animals; Biocompatible Materials; Biomimetic Materials; Circular Dichroism; Escherichia coli; Female; Fibroins; Gene Library; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Lysine; Magnetic Resonance Spectroscopy; Mantodea; Molecular Sequence Data; Molecular Weight; Ovum; Protein Structure, Secondary; Recombinant Proteins; Scleroproteins; Sequence Alignment; Sequence Analysis, DNA; Serine | 2012 |
In vitro degradation of lysine by ruminal fluid-based fermentations and by Fusobacterium necrophorum.
Topics: Acetic Acid; Alanine; Animals; Cattle; Fermentation; Fusobacterium necrophorum; Gastric Juice; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Lysine; Methionine; Propionates; Rumen; Tryptophan | 2013 |
Accelerated pentose utilization by Corynebacterium glutamicum for accelerated production of lysine, glutamate, ornithine and putrescine.
Topics: Aldose-Ketose Isomerases; Amino Acids; Biotechnology; Corynebacterium glutamicum; Culture Media; Fermentation; Genetic Engineering; Glutamic Acid; Lysine; Ornithine; Phosphotransferases (Alcohol Group Acceptor); Putrescine; Recombinant Proteins; Xylose | 2013 |
Clinical experiences with Creutzfeldt-Jakob disease: three case studies.
Topics: Aged; Autopsy; Brain; Cerebellar Ataxia; Creutzfeldt-Jakob Syndrome; Diagnosis, Differential; Electroencephalography; Fatal Outcome; Female; Glutamic Acid; Humans; Lysine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Prion Proteins; Prions; Seizures; Speech Disorders | 2012 |
Amino acid turnover by human oocytes is influenced by gamete developmental competence, patient characteristics and gonadotrophin treatment.
Topics: Age Factors; Alanine; Amino Acids; Arginine; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Female; Follicle Stimulating Hormone; Glutamic Acid; Glutamine; Gonadotropins; Humans; Infertility, Female; Isoleucine; Kinetics; Lysine; Metaphase; Oocytes; Ovulation Induction; Polycystic Ovary Syndrome; Serine; Valine | 2013 |
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
Topics: 2-Aminoadipic Acid; Archaeal Proteins; Arginine; Bacterial Proteins; Carrier Proteins; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Evolution, Molecular; Gene Duplication; Glutamic Acid; Lysine; Models, Molecular; Ornithine; Phylogeny; Protein Binding; Protein Interaction Domains and Motifs; Recombinant Proteins; Substrate Specificity; Sulfolobus acidocaldarius; Thermus | 2013 |
Adhesiveness of various glass ionomer cements in cavities treated with Carisolv.
Topics: Adhesiveness; Bicuspid; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Etching; Dental Leakage; Dental Restoration, Permanent; Dentin; Dentin-Bonding Agents; Edetic Acid; Glass Ionomer Cements; Glutamic Acid; Humans; Leucine; Lysine; Molar; Smear Layer; Tooth Cervix; Wettability | 2012 |
Awareness of dental surgeons in Pune and Mumbai, India, regarding chemomechanical caries removal system.
Topics: Adult; Aminobutyrates; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Dentin; Dentists; Education, Dental, Continuing; Female; Glutamic Acid; Humans; India; Leucine; Lysine; Male; Papain; Professional Practice; Surveys and Questionnaires; Time Factors | 2013 |
A biochemical correlate of dimorphism in a zygomycete Benjaminiella poitrasii: characterization of purified NAD-dependent glutamate dehydrogenase, a target for antifungal agents.
Topics: Ammonium Chloride; Antifungal Agents; Candida albicans; Catalysis; Chromatography, Agarose; Drug Evaluation, Preclinical; Fungal Proteins; Glutamate Dehydrogenase; Glutamic Acid; Histidine; Hyphae; Isoelectric Point; Ketoglutaric Acids; Lysine; Molecular Targeted Therapy; Molecular Weight; Mucorales; NAD; Phosphorylation; Protein Processing, Post-Translational; Substrate Specificity; Triazoles; Yarrowia | 2013 |
Exploration of fluoroquinolone resistance in Streptococcus pyogenes: comparative structure analysis of wild-type and mutant DNA gyrase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; DNA Gyrase; Drug Resistance, Bacterial; Fluoroquinolones; Glutamic Acid; Lysine; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Mutation; Phylogeny; Protein Structure, Secondary; Sequence Homology; Streptococcus pyogenes | 2013 |
Importance of a Lys113-Glu195 intermonomer ionic bond in F-actin stabilization and regulation by yeast formins Bni1p and Bnr1p.
Topics: Actins; Allosteric Site; Circular Dichroism; Cytoskeletal Proteins; Cytoskeleton; Gene Expression Regulation, Fungal; Glutamic Acid; Lysine; Microfilament Proteins; Mitochondria; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2013 |
HIV-1 resistance mechanism to an electrostatically constrained peptide fusion inhibitor that is active against T-20-resistant strains.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line, Tumor; Drug Resistance, Viral; Enfuvirtide; Glutamic Acid; HIV Envelope Protein gp41; HIV Fusion Inhibitors; HIV-1; Humans; Lysine; Molecular Sequence Data; Peptide Fragments; Protein Structure, Secondary; Static Electricity | 2013 |
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer.
Topics: Acetates; Animals; Antigens, Surface; Biological Transport; Cell Line, Tumor; Chelating Agents; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Lysine; Male; Mice; Molecular Imaging; Organotechnetium Compounds; Prostatic Neoplasms; Protease Inhibitors; Radiochemistry; Radionuclide Imaging; Technetium; Urea | 2013 |
Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age.
Topics: Aging; Animals; Cells, Cultured; Cytoplasmic Dyneins; Embryo, Mammalian; Female; Glucagon; Glutamic Acid; Humans; Insulin; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Muscular Atrophy, Spinal; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Transfection | 2013 |
Pharmacologic Approach to Defective Protein Trafficking in the E637K-hERG Mutant with PD-118057 and Thapsigargin.
Topics: Amino Acid Substitution; Chlorobenzenes; Endoplasmic Reticulum Stress; ERG1 Potassium Channel; Glutamic Acid; HEK293 Cells; Humans; Long QT Syndrome; Lysine; Mutant Proteins; Mutation, Missense; ortho-Aminobenzoates; Patch-Clamp Techniques; Protein Transport; Thapsigargin; Unfolded Protein Response | 2013 |
The effect of the PB2 mutation 627K on highly pathogenic H5N1 avian influenza virus is dependent on the virus lineage.
Topics: Amino Acid Substitution; Animals; Asia; Cell Line; Chickens; Europe; Genomic Instability; Glutamic Acid; Humans; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Lysine; Mutagenesis, Site-Directed; Mutant Proteins; Mutation, Missense; Reverse Genetics; RNA-Dependent RNA Polymerase; Viral Proteins; Virus Replication | 2013 |
Functional identification of the general acid and base in the dehydration step of indole-3-glycerol phosphate synthase catalysis.
Topics: Anti-Bacterial Agents; Catalysis; Catalytic Domain; Crystallography, X-Ray; Escherichia coli; Glutamic Acid; Indole-3-Glycerol-Phosphate Synthase; Lysine; Mutagenesis, Site-Directed; Protein Engineering; Solvents; Tryptophan; Viscosity | 2013 |
Chemical, morphological and microhardness changes of dentine after chemomechanical caries removal.
Topics: Dental Caries; Dental Cavity Preparation; Dentin; Glutamic Acid; Hardness; Hardness Tests; Humans; Leucine; Lysine; Molar; Papain; Random Allocation | 2013 |
Inhibitory gradient along the dorsoventral axis in the medial entorhinal cortex.
Topics: Action Potentials; Animals; Animals, Newborn; Electric Stimulation; Entorhinal Cortex; Evoked Potentials; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lysine; Nerve Net; Neural Inhibition; Parvalbumins; Patch-Clamp Techniques; Peptides; Polymers; Rats; Rats, Wistar; Statistics, Nonparametric; Vesicular Inhibitory Amino Acid Transport Proteins | 2013 |
Substitution of glutamate residue by lysine in the dimerization domain affects DNA binding ability of HapR by inducing structural deformity in the DNA binding domain.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Chromatography, Gel; Circular Dichroism; DNA; Electrophoresis, Polyacrylamide Gel; Glutamic Acid; Lysine; Molecular Sequence Data; Molecular Weight; Mutant Proteins; Protein Binding; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Scattering, Small Angle; Sequence Alignment; Vibrio cholerae; X-Ray Diffraction | 2013 |
Chronotropic and dromotropic responses to localized glutamate microinjections in the rat nucleus ambiguus.
Topics: Animals; Biotin; Blood Pressure; Electrocardiography; Excitatory Amino Acid Agonists; Glutamic Acid; Heart Conduction System; Heart Rate; Lysine; Microinjections; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Vagus Nerve | 2014 |
Acidic residue Glu199 increases SUMOylation level of nuclear hormone receptor NR5A1.
Topics: Alanine; Amino Acid Substitution; Animals; Glutamic Acid; Lysine; Mice; Signal Transduction; Steroidogenic Factor 1; Substrate Specificity; Sumoylation | 2013 |
Structure of MurNAc 6-phosphate hydrolase (MurQ) from Haemophilus influenzae with a bound inhibitor.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding, Competitive; Biocatalysis; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli Proteins; Glutamic Acid; Glycoside Hydrolases; Haemophilus influenzae; Hydrogen Bonding; Hydrolysis; Lysine; Models, Molecular; Molecular Conformation; Muramic Acids; Phosphorylation; Recombinant Proteins | 2013 |
The conserved Lys-95 charged residue cluster is critical for the homodimerization and enzyme activity of human ribonucleotide reductase small subunit M2.
Topics: Amino Acid Substitution; Biocatalysis; Cell Proliferation; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; G1 Phase Cell Cycle Checkpoints; Glutamic Acid; Green Fluorescent Proteins; HEK293 Cells; HeLa Cells; Humans; Immunoblotting; Lysine; Microscopy, Confocal; Models, Molecular; Mutation; Protein Multimerization; Ribonucleoside Diphosphate Reductase; RNA Interference | 2014 |
The effect of caries excavation methods on the bond strength of etch-and-rinse and self-etch adhesives to caries affected dentine.
Topics: Analysis of Variance; Bisphenol A-Glycidyl Methacrylate; Composite Resins; Dental Bonding; Dental Caries; Dental Etching; Dentin-Bonding Agents; Glutamic Acid; Humans; Leucine; Lysine; Mandible; Molar; Tensile Strength | 2013 |
Role of active site residues in promoting cobalt-carbon bond homolysis in adenosylcobalamin-dependent mutases revealed through experiment and computation.
Topics: Cobalt; Cobamides; Glutamic Acid; Hydrogen Bonding; Intramolecular Transferases; Lysine; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation | 2014 |
Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study.
Topics: Aged; Animals; Antiviral Agents; China; Commerce; DNA, Viral; Fatal Outcome; Female; Glutamic Acid; Humans; Influenza A virus; Influenza A Virus, H9N2 Subtype; Influenza in Birds; Influenza, Human; Lysine; Multiple Organ Failure; Neuraminidase; Phylogeny; Poultry; Reverse Transcriptase Polymerase Chain Reaction; RNA-Dependent RNA Polymerase; Sequence Analysis, DNA; Trachea; Viral Proteins | 2014 |
Energy cost for the proper ionization of active site residues in 6-phosphogluconate dehydrogenase from T. brucei.
Topics: Catalytic Domain; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Phosphogluconate Dehydrogenase; Protein Binding; Protons; Protozoan Proteins; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Trypanosoma brucei brucei | 2014 |
Z α1-antitrypsin confers a proinflammatory phenotype that contributes to chronic obstructive pulmonary disease.
Topics: alpha 1-Antitrypsin; Animals; Biomarkers; Disease Models, Animal; Endoplasmic Reticulum; Glutamic Acid; Humans; Interleukin-6; Lysine; Macrophages; Mice; Mice, Transgenic; Mutation; Neutrophils; NF-kappa B; Oxidative Stress; Phenotype; Pulmonary Disease, Chronic Obstructive; Tobacco Smoke Pollution; Trypsin Inhibitors; Tumor Necrosis Factor-alpha | 2014 |
V-type nerve agents phosphonylate ubiquitin at biologically relevant lysine residues and induce intramolecular cyclization by an isopeptide bond.
Topics: Amino Acid Sequence; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Cyclization; Glutamic Acid; Humans; Lysine; Models, Molecular; Molecular Sequence Data; Organothiophosphorus Compounds; Phosphorous Acids; Solutions; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Ubiquitin | 2014 |
Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.
Topics: alpha-Synuclein; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Gene Expression Regulation; Glutamic Acid; Humans; Lewy Body Disease; Lysine; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Synapses; Thy-1 Antigens | 2014 |
Renal ApoA-1 amyloidosis with Glu34Lys mutation and intra-amyloid lipid accumulation.
Topics: Adult; Amyloidosis; Apolipoprotein A-I; Biopsy; Glutamic Acid; Humans; Immunohistochemistry; Infertility, Male; Kidney; Lipids; Lysine; Male; Microscopy, Fluorescence; Mutation; Sertoli Cells; Testis | 2014 |
Preliminary X-ray crystallographic analysis of an engineered glutamyl-tRNA synthetase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Crystallography, X-Ray; Escherichia coli; Gene Expression; Glutamate-tRNA Ligase; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Engineering; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Structural Homology, Protein; Substrate Specificity | 2014 |
Cooperative and competitive adsorption of amino acids with Ca²⁺ on rutile (α-TiO₂).
Topics: Adsorption; Amino Acids; Calcium; Carbon Cycle; Cations, Divalent; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Static Electricity; Surface Properties; Titanium; Water | 2014 |
Investigation of nonfouling polypeptides of poly(glutamic acid) with lysine side chains synthesized by EDC·HCl/HOBt chemistry.
Topics: Adsorption; Biocompatible Materials; Biofouling; Cell Survival; Chemistry Techniques, Synthetic; Ethyldimethylaminopropyl Carbodiimide; Fibrinogen; Glutamic Acid; Hemolysis; Human Umbilical Vein Endothelial Cells; Humans; Hydrochloric Acid; Immunoglobulin G; Lysine; Peptides; Triazoles | 2014 |
Polyelectrolyte multilayer-calcium phosphate composite coatings for metal implants.
Topics: Aspartic Acid; Calcium Phosphates; Coated Materials, Biocompatible; Crystallization; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Metals; Osmolar Concentration; Polymers; Prostheses and Implants; Surface Properties; Titanium | 2014 |
[Homozygous E387K (1159G>A) mutation of the CYP1B1 gene in a Roma boy affected with primary congenital glaucoma. Case report].
Topics: Aryl Hydrocarbon Hydroxylases; Child, Preschool; Cytochrome P-450 CYP1B1; Genetic Counseling; Glaucoma; Glutamic Acid; Humans; Hungary; Lysine; Male; Mutation; Roma; Slovakia | 2014 |
Associations of a polymorphism in the intercellular adhesion molecule-1 (ICAM1) gene and ICAM1 serum levels with migraine in a Chinese Han population.
Topics: Adolescent; Adult; Asian People; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Humans; Intercellular Adhesion Molecule-1; Logistic Models; Lysine; Male; Middle Aged; Migraine Disorders; Polymorphism, Single Nucleotide; Risk Factors; RNA, Messenger; Young Adult | 2014 |
Viability of intratubular bacteria after chemomechanical caries removal.
Topics: Chlorhexidine; Dental Caries; Dental Cavity Preparation; Dental Disinfectants; Dentin; Fluorescent Dyes; Gels; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Leucine; Lysine; Materials Testing; Microbial Viability; Microscopy, Confocal; Microscopy, Electron, Scanning; Papain; Random Allocation; Sodium Hypochlorite; Streptococcus mutans; Time Factors | 2014 |
An electrostatic interaction at the tetrahelix bundle promotes phosphorylation-dependent cystic fibrosis transmembrane conductance regulator (CFTR) channel opening.
Topics: Adenosine Triphosphate; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Glutamic Acid; HEK293 Cells; Humans; Ion Channel Gating; Lysine; Molecular Dynamics Simulation; Mutation, Missense; Phosphorylation; Protein Binding; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Processing, Post-Translational; Protein Structure, Secondary | 2014 |
Promoting the selection and maintenance of fetal liver stem/progenitor cell colonies by layer-by-layer polypeptide tethered supported lipid bilayer.
Topics: Fetus; Glutamic Acid; Lipid Bilayers; Liver; Lysine; Peptides; Stem Cells; Surface Properties | 2014 |
Effect of external pulling forces on the length distribution of peptides.
Topics: Arginine; Glutamic Acid; Glycine; Lysine; Molecular Dynamics Simulation; Oligopeptides; Protein Structure, Secondary; Stress, Mechanical; Structure-Activity Relationship; Surface Properties | 2015 |
A comparative clinical study of various methods of caries removal in children.
Topics: Adolescent; Child; Child, Preschool; Coloring Agents; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Dental Materials; Dentin; Equipment Design; Glutamic Acid; Humans; Leucine; Lysine; Molar; Pain Measurement; Pain Threshold; Polymers; Random Allocation; Time Factors; Tooth, Deciduous; Treatment Outcome | 2015 |
Resolving self-association of a therapeutic antibody by formulation optimization and molecular approaches.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Diphtheria Toxin; Gels; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Immunoglobulin Heavy Chains; Lysine; Models, Molecular; Protein Binding; Protein Engineering; Protein Structure, Tertiary; Static Electricity; Temperature | 2014 |
Regulation of free glutamate content in meat by dietary lysine in broilers.
Topics: 2-Aminoadipic Acid; Animal Feed; Animals; Chickens; Dietary Supplements; Female; Food Quality; Glutamic Acid; Liver; Lysine; Meat; Muscles; Pipecolic Acids; RNA, Messenger; Saccharopine Dehydrogenases | 2015 |
Effect of chemomechanical caries removal on bonding of self-etching adhesives to caries-affected dentin.
Topics: Composite Resins; Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Leakage; Dental Materials; Dental Restoration, Permanent; Dentin; Dentin-Bonding Agents; Equipment Design; Glutamic Acid; Humans; Leucine; Lysine; Materials Testing; Microscopy, Electron, Scanning; Molar; Papain; Resin Cements; Silver Staining; Stress, Mechanical; Tensile Strength | 2014 |
Familial Creutzfeldt-Jakob disease with the E200K mutation: longitudinal neuroimaging from asymptomatic to symptomatic CJD.
Topics: Adult; Brain; Creutzfeldt-Jakob Syndrome; Electroencephalography; Female; Glutamic Acid; Humans; Image Processing, Computer-Assisted; Longitudinal Studies; Lysine; Magnetic Resonance Imaging; Male; Mental Status Schedule; Middle Aged; Mutation; Neuroimaging; Prion Proteins; Prions | 2015 |
Expanding the phenotypic spectrum and variability of endocrine abnormalities associated with TUBB3 E410K syndrome.
Topics: Adult; Aged; Amino Acid Substitution; Child; Child, Preschool; Developmental Disabilities; Endocrine System Diseases; Eye Diseases, Hereditary; Female; Fibrosis; Glutamic Acid; Humans; Kallmann Syndrome; Lysine; Male; Ophthalmoplegia; Pedigree; Phenotype; Syndrome; Tubulin | 2015 |
Fluoro-substituted phenylazocarboxamides: Dopaminergic behavior and N-arylating properties for irreversible binding.
Topics: Amides; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Fluorine; Glutamic Acid; HEK293 Cells; Humans; Ligands; Lysine; Molecular Structure; Mutation; Receptors, Dopamine D3; Structure-Activity Relationship | 2015 |
Importance of glutamate 87 and the substrate α-amine for the reaction catalyzed by D-arginine dehydrogenase.
Topics: Amines; Amino Acid Oxidoreductases; Arginine; Glutamic Acid; Hydrogen-Ion Concentration; Leucine; Lysine; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Pseudomonas aeruginosa; Substrate Specificity | 2015 |
Effect of charged amino acid side chain length on lateral cross-strand interactions between carboxylate- and guanidinium-containing residues in a β-hairpin.
Topics: 2-Aminoadipic Acid; Alanine; Arginine; Aspartic Acid; Databases, Protein; Glutamic Acid; Guanidines; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lysine; Models, Molecular; Protein Folding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protein Structure, Tertiary; Static Electricity; Thermodynamics | 2015 |
Local and macroscopic electrostatic interactions in single α-helices.
Topics: Amino Acid Sequence; Computational Biology; Glutamic Acid; Lysine; Models, Molecular; Molecular Sequence Data; Myosins; Peptides; Protein Folding; Protein Structure, Secondary; Protein Unfolding; Static Electricity | 2015 |
Inactivation of myeloperoxidase by benzoic acid hydrazide.
Topics: Amino Acid Sequence; Aniline Compounds; Animals; Benzoic Acid; Carbocyanines; Catalytic Domain; Cattle; Electrons; Enzyme Inhibitors; Fluorescent Dyes; Free Radicals; Glutamic Acid; Heme; Humans; Hydrogen Peroxide; Inflammation; Lysine; Mass Spectrometry; Methionine; Molecular Conformation; Molecular Sequence Data; Neutrophils; Oxygen; Peroxidase; Spectrometry, Fluorescence | 2015 |
Effect of silver diamine fluoride and potassium iodide on residual bacteria in dentinal tubules.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Chlorhexidine; Dentin; Fluorescent Dyes; Fluorides, Topical; Glutamic Acid; Humans; Leucine; Lysine; Microbial Viability; Microscopy, Confocal; Papain; Potassium Iodide; Quaternary Ammonium Compounds; Silver Compounds; Sodium Hypochlorite; Streptococcus mutans | 2015 |
Effect of lysine to arginine mutagenesis in the V3 loop of HIV-1 gp120 on viral entry efficiency and neutralization.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Cell Line, Transformed; Chemokine CCL5; Chemokine CXCL12; Gene Expression Regulation, Viral; Glutamic Acid; HeLa Cells; HIV Envelope Protein gp120; HIV-1; Host-Pathogen Interactions; Humans; Lysine; Molecular Sequence Data; Mutagenesis; Protein Binding; Protein Structure, Secondary; Receptors, CCR4; Receptors, CCR5; Signal Transduction; Static Electricity; Virus Internalization | 2015 |
Effect of chemomechanical caries removal on bonding of resin-modified glass ionomer cement adhesives to caries-affected dentine.
Topics: Dental Bonding; Dental Caries; Dental Cavity Preparation; Dental Restoration, Permanent; Dentin; Dentin-Bonding Agents; Glass Ionomer Cements; Glutamic Acid; Humans; Leucine; Lysine; Microscopy, Electron, Scanning; Molar; Papain; Tensile Strength | 2015 |
13C NMR based profiling unveils different α-ketoglutarate pools involved into glutamate and lysine synthesis in the milk yeast Kluyveromyces lactis.
Topics: Carbon-13 Magnetic Resonance Spectroscopy; Glutamic Acid; Ketoglutaric Acids; Kluyveromyces; Lysine | 2015 |
Effects of Lys to Glu mutations in GsMTx4 on membrane binding, peptide orientation, and self-association propensity, as analyzed by molecular dynamics simulations.
Topics: Cell Membrane; Glutamic Acid; Intercellular Signaling Peptides and Proteins; Kinetics; Lipid Bilayers; Lysine; Membrane Lipids; Molecular Dynamics Simulation; Mutation, Missense; Peptides; Phosphatidylcholines; Protein Binding; Spider Venoms; Thermodynamics | 2015 |
Methylglyoxal and carboxyethyllysine reduce glutamate uptake and S100B secretion in the hippocampus independently of RAGE activation.
Topics: Animals; Astrocytes; Biological Transport; Diabetes Mellitus; Energy Metabolism; Glucose; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Hyperglycemia; Lysine; Male; Oxidation-Reduction; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; S100 Calcium Binding Protein beta Subunit | 2016 |
EKylation: Addition of an Alternating-Charge Peptide Stabilizes Proteins.
Topics: Anions; Cations; Glutamic Acid; Kinetics; Lysine; Peptides; Proteins | 2015 |
Enhancing constant-pH simulation in explicit solvent with a two-dimensional replica exchange method.
Topics: Animals; Aspartic Acid; Cardiotoxins; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Molecular Dynamics Simulation; Peptides; Snakes; Solvents; Thermodynamics | 2015 |
Lysine mediation of neuroendocrine food regulation in guinea fowl.
Topics: Animal Feed; Animals; Diet; Dietary Supplements; Feeding Behavior; Galliformes; Glutamic Acid; Homeostasis; Hypothalamus; Liver; Lysine; Male; Neurosecretory Systems; Random Allocation; Signal Transduction | 2016 |
Altered acetylation and succinylation profiles in Corynebacterium glutamicum in response to conditions inducing glutamate overproduction.
Topics: Acetylation; Amino Acid Sequence; Bioreactors; Corynebacterium glutamicum; Gene Expression Regulation, Bacterial; Glutamic Acid; Lysine; Mass Spectrometry; Metabolic Networks and Pathways; Phosphate Acetyltransferase; Protein Processing, Post-Translational; Proteome | 2016 |
Corynebacterium glutamicum Metabolic Engineering with CRISPR Interference (CRISPRi).
Topics: Clustered Regularly Interspaced Short Palindromic Repeats; Corynebacterium glutamicum; Gene Expression Regulation, Bacterial; Glutamic Acid; Lysine; Metabolic Engineering; Metabolic Networks and Pathways; RNA | 2016 |
Gene expression patterns in transgenic mouse models of hypertrophic cardiomyopathy caused by mutations in myosin regulatory light chain.
Topics: Algorithms; Animals; Arginine; Cardiomyopathy, Hypertrophic; Computational Biology; Gene Expression Profiling; Gene Expression Regulation; Glutamic Acid; Glutamine; Lysine; Mice; Mice, Transgenic; Multigene Family; Mutation; Myocardium; Myosin Light Chains; Oligonucleotide Array Sequence Analysis; Phenotype; Principal Component Analysis; Valine | 2016 |
Clinical Efficiency of Three Caries Removal Systems: Rotary Excavation, Carisolv, and Papacarie.
Topics: Child; Child, Preschool; Cross-Over Studies; Dental Caries; Dental Cavity Preparation; Dental High-Speed Equipment; Female; Glutamic Acid; Humans; Leucine; Lysine; Male; Pain Measurement; Papain; Treatment Outcome | 2016 |
Innovative chemical synthesis and conformational hints on the lipopeptide liraglutide.
Topics: Amino Acid Sequence; Fluorenes; Glutamic Acid; Humans; Hypoglycemic Agents; Lipopeptides; Liraglutide; Lysine; Membranes, Artificial; Phosphatidylcholines; Protein Conformation; Sodium Dodecyl Sulfate; Solid-Phase Synthesis Techniques; Trifluoroethanol | 2016 |
Influence of Glu/Arg, Asp/Arg, and Glu/Lys Salt Bridges on α-Helical Stability and Folding Kinetics.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Circular Dichroism; Glutamic Acid; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Least-Squares Analysis; Lysine; Molecular Dynamics Simulation; Peptides; Protein Folding; Protein Stability; Protein Structure, Secondary; Spectrum Analysis; Static Electricity; Thermodynamics | 2016 |
Functional Complementation Analysis (FCA): A Laboratory Exercise Designed and Implemented to Supplement the Teaching of Biochemical Pathways.
Topics: Biochemical Phenomena; Diaminopimelic Acid; Glutamic Acid; Lysine; Peptidoglycan | 2016 |
Hydrogen Rearrangement Rules: Computational MS/MS Fragmentation and Structure Elucidation Using MS-FINDER Software.
Topics: Cohort Studies; Glutamic Acid; Glutathione; Humans; Hydrogen; Lysine; Molecular Structure; Phenylurea Compounds; Phosphorylcholine; Software; Tandem Mass Spectrometry | 2016 |
Structure of the human DNA-repair protein RAD52 containing surface mutations.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; DNA; DNA Repair; Escherichia coli; Gene Expression; Glutamic Acid; Humans; Lysine; Models, Molecular; Mutation; Plasmids; Protein Binding; Protein Folding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Rad52 DNA Repair and Recombination Protein; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Static Electricity | 2016 |
Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers.
Topics: Aspartic Acid; Cell Line, Tumor; Cell Membrane; Cell Membrane Permeability; Cell Survival; Deoxycholic Acid; Electric Impedance; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Lysine; Mouth Mucosa | 2016 |
Polyphosphate colocalizes with factor XII on platelet-bound fibrin and augments its plasminogen activator activity.
Topics: Blood Platelets; Complement C1 Inhibitor Protein; Factor XII; Fibrin; Glutamic Acid; HeLa Cells; Humans; Lysine; Plasminogen; Polyphosphates; Proteins | 2016 |
PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation.
Topics: Acetylation; Amino Acid Sequence; Antigens, Neoplasm; Aspartic Acid; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Glutamic Acid; Histones; Humans; Lung Neoplasms; Lysine; Methylation; Models, Biological; Models, Molecular; Mutation; Protein Binding; Protein Domains; Transcription Factors; Tumor Suppressor Protein p53 | 2016 |
Insight into the collagen assembly in the presence of lysine and glutamic acid: An in vitro study.
Topics: Collagen; Glutamic Acid; Kinetics; Lysine; Microscopy, Atomic Force; Nephelometry and Turbidimetry; Pyrenes; Spectrometry, Fluorescence; Static Electricity; Thermodynamics | 2017 |
Chemical Mechanism of the Branched-Chain Aminotransferase IlvE from Mycobacterium tuberculosis.
Topics: Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Catalytic Domain; Glutamic Acid; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Lysine; Models, Chemical; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Protein Conformation; Pyridoxal Phosphate; Transaminases; Valine | 2016 |
Localization of a mutant SOD1 protein in E40K-heterozygous dogs: Implications for non-cell-autonomous pathogenesis of degenerative myelopathy.
Topics: Amyotrophic Lateral Sclerosis; Animals; Antibodies; Calcium-Binding Proteins; Disease Models, Animal; DNA-Binding Proteins; Dogs; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; HEK293 Cells; Humans; Immunoprecipitation; Lysine; Microfilament Proteins; Mutation; Spinal Cord; Superoxide Dismutase-1; Transfection | 2017 |
Microscopic mechanisms that govern the titration response and pK
Topics: Aspartic Acid; Glutamic Acid; Isoelectric Point; Kinetics; Lysine; Micrococcal Nuclease; Molecular Dynamics Simulation; Mutation; Protein Domains; Protein Folding; Protein Structure, Secondary; Staphylococcus; Structure-Activity Relationship; Thermodynamics | 2017 |
Determinants of the VP1/2A junction cleavage by the 3C protease in foot-and-mouth disease virus-infected cells.
Topics: 3C Viral Proteases; Amino Acid Substitution; Animals; Antiviral Agents; Capsid; Capsid Proteins; Cysteine Endopeptidases; Drug Evaluation, Preclinical; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Glutamic Acid; Lysine; Mutation; Viral Proteins; Virus Assembly | 2017 |
Antibacterial Activity of Two Chemomechanical Caries Removal Gels on Carious Dentin of Primary Teeth: An in vitro Study.
Topics: Anti-Bacterial Agents; Carica; Dental Caries; Dental Cavity Preparation; Dentin; Gels; Glutamic Acid; Humans; In Vitro Techniques; Lactobacillus acidophilus; Leucine; Lysine; Molar; Plant Extracts; Streptococcus mutans; Tooth, Deciduous | 2016 |
Unveiling the Pathogenic Molecular Mechanisms of the Most Common Variant (p.K329E) in Medium-Chain Acyl-CoA Dehydrogenase Deficiency by in Vitro and in Silico Approaches.
Topics: Acyl-CoA Dehydrogenase; Biocatalysis; Computer Simulation; Enzyme Stability; Glutamic Acid; Humans; Kinetics; Lipid Metabolism, Inborn Errors; Lysine; Models, Molecular; Motion; Mutation, Missense; Principal Component Analysis; Protein Binding; Protein Domains; Protein Multimerization; Temperature | 2016 |
Peptide hydrogel in vitro non-inflammatory potential.
Topics: Animals; Biocompatible Materials; Biomarkers; Cell Culture Techniques; Cell Line; Cell Proliferation; Cell Survival; Cells, Immobilized; Gene Expression; Glutamic Acid; Hydrogels; Interleukin-1beta; Interleukin-6; Lysine; Mice; Monocytes; Peptides; Phenylalanine; Protein Structure, Secondary; Tissue Scaffolds; Tumor Necrosis Factor-alpha | 2017 |
Controlling Self-Assembling Peptide Hydrogel Properties through Network Topology.
Topics: Arginine; Glutamic Acid; Hydrogels; Hydrophobic and Hydrophilic Interactions; Lysine; Mechanical Phenomena; Microscopy, Electron, Transmission; Models, Theoretical; Peptides; Phenylalanine; Scattering, Small Angle; Spectroscopy, Fourier Transform Infrared; Tissue Scaffolds | 2017 |
Target Cell Type-Dependent Differences in Ca
Topics: Action Potentials; Animals; Animals, Newborn; Axons; Calcium; Calcium Channels; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lysine; Male; Nerve Tissue Proteins; Neuronal Plasticity; Neurons; Parvalbumins; Presynaptic Terminals; Probability; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 2017 |
Identification of a Sgo2-Dependent but Mad2-Independent Pathway Controlling Anaphase Onset in Fission Yeast.
Topics: Anaphase; Anaphase-Promoting Complex-Cyclosome; Asparagine; Aurora Kinase B; Cell Cycle; Cell Cycle Proteins; Centromere; Cyclin B; Glutamic Acid; Kinetochores; Lysine; Nuclear Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Spindle Apparatus | 2017 |
Characterization of lysine acetylation of a phosphoenolpyruvate carboxylase involved in glutamate overproduction in Corynebacterium glutamicum.
Topics: Acetylation; Corynebacterium glutamicum; Glutamic Acid; Lysine; Phosphoenolpyruvate Carboxylase; Protein Processing, Post-Translational; Pyruvate Carboxylase | 2017 |
Mutagen resistance and mutation restriction of St. Louis encephalitis virus.
Topics: Amino Acid Substitution; Antiviral Agents; Drug Resistance, Viral; Encephalitis Virus, St. Louis; Encephalitis, St. Louis; Glutamic Acid; HeLa Cells; Humans; Lysine; Models, Molecular; Mutagens; Mutation; Nucleosides; Protein Domains; Pyrazines; Ribavirin; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins | 2017 |
Characterization of long and stable de novo single alpha-helix domains provides novel insight into their stability.
Topics: Amino Acid Sequence; Arginine; Glutamic Acid; Hydrogen Bonding; Lysine; Models, Molecular; Molecular Dynamics Simulation; Peptides; Protein Conformation, alpha-Helical; Protein Folding; Protein Stability; Thermodynamics | 2017 |
Glutaredoxin catalysis requires two distinct glutathione interaction sites.
Topics: Binding Sites; Catalysis; Glutamic Acid; Glutaredoxins; Glutathione; Kinetics; Lysine; Mutation; Oxidation-Reduction; Structure-Activity Relationship | 2017 |
An unmodified wobble uridine in tRNAs specific for Glutamine, Lysine, and Glutamic acid from Salmonella enterica Serovar Typhimurium results in nonviability-Due to increased missense errors?
Topics: Glutamic Acid; Glutamine; Lysine; Mutation, Missense; RNA, Transfer; Salmonella typhimurium; Uridine | 2017 |
The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Carbodiimides; Complement C4b; Complement Pathway, Classical; Complement Pathway, Mannose-Binding Lectin; Cross-Linking Reagents; Crystallography, X-Ray; Gene Expression; Glutamic Acid; Host-Pathogen Interactions; Humans; Lysine; Models, Molecular; Mutation; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; RNA-Binding Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Staphylococcus aureus | 2017 |
Chitosan/γ-poly(glutamic acid) scaffolds with surface-modified albumin, elastin and poly-l-lysine for cartilage tissue engineering.
Topics: Albumins; Animals; Cartilage; Cattle; Chitosan; Chondrocytes; Elastin; Glutamic Acid; Humans; Lysine; Materials Testing; Polyesters; Porosity; Tissue Engineering; Tissue Scaffolds | 2017 |
The Conserved Lysine-265 Allosterically Modulates Nucleotide- and Actin-binding Site Coupling in Myosin-2.
Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Allosteric Regulation; Binding Sites; Enzyme Activation; Gene Expression; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Mutation; Myosin Type II; Nucleotides; Protein Binding; Structure-Activity Relationship | 2017 |
Effect of lysine succinylation on the regulation of 2-oxoglutarate dehydrogenase inhibitor, OdhI, involved in glutamate production in Corynebacterium glutamicum.
Topics: Amino Acid Sequence; Corynebacterium glutamicum; Enzyme Inhibitors; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Lysine; Models, Molecular; Mutation; Phosphorylation; Protein Domains; Protein Processing, Post-Translational; Succinic Acid | 2017 |
Effect of amino acid mutations on intra-dimer tubulin-tubulin binding strength of microtubules.
Topics: Arginine; Aspartic Acid; Binding Sites; Computer Simulation; Dimerization; Glutamic Acid; Humans; Lysine; Microtubules; Models, Molecular; Mutation; Protein Binding; Protein Conformation; Static Electricity; Stress, Mechanical; Tensile Strength; Tubulin | 2017 |
Oligomer-prone E57K-mutant alpha-synuclein exacerbates integration deficit of adult hippocampal newborn neurons in transgenic mice.
Topics: alpha-Synuclein; Animals; Bromodeoxyuridine; Caspase 3; Cell Proliferation; Disease Models, Animal; Doublecortin Domain Proteins; Gene Expression Regulation; Glutamic Acid; Hippocampus; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Mutation; Neurodegenerative Diseases; Neurogenesis; Neurons; Neuropeptides; Phosphopyruvate Hydratase; SOXB1 Transcription Factors | 2018 |
TUBB3 E410K syndrome with osteoporosis and cough syncope in a patient previously diagnosed with atypical Moebius syndrome.
Topics: Adult; Corpus Callosum; Eye Movements; Female; Glutamic Acid; Humans; Japan; Lysine; Magnetic Resonance Imaging; Mobius Syndrome; Mutation; Osteoporosis; Pons; Syncope; Tubulin | 2018 |
Post mortem single-cell labeling with DiI and immunoelectron microscopy unveil the fine structure of kisspeptin neurons in humans.
Topics: Aged; Aged, 80 and over; Autopsy; Axons; Carbocyanines; Cell Body; Dendrites; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypothalamus; Imaging, Three-Dimensional; Kisspeptins; Lysine; Male; Microscopy, Confocal; Microscopy, Immunoelectron; Middle Aged; Nerve Net; Neurons; Synapses; Vesicular Glutamate Transport Protein 2; Vesicular Inhibitory Amino Acid Transport Proteins | 2018 |
Synthesis and Binding of a Novel PSMA-specific Conjugate.
Topics: Antigens, Surface; Cell Line, Tumor; Dextrans; Fluorescein-5-isothiocyanate; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Lysine; Male; Microscopy, Fluorescence; Molecular Targeted Therapy; Prostatic Neoplasms, Castration-Resistant; Protein Binding; Radiopharmaceuticals; Urea | 2018 |
XPlex: An Effective, Multiplex Cross-Linking Chemistry for Acidic Residues.
Topics: Algorithms; Aspartic Acid; Computational Biology; Cross-Linking Reagents; Esters; Glutamic Acid; Lysine; Mass Spectrometry; Proteins; Serine; Succinimides; Temperature | 2018 |
A tomato proline-, lysine-, and glutamic-rich type gene SpPKE1 positively regulates drought stress tolerance.
Topics: Adaptation, Physiological; Amino Acid Sequence; Amino Acids; Base Sequence; Droughts; F-Box Proteins; Genes, Plant; Glutamic Acid; Lysine; Plant Proteins; Plants, Genetically Modified; Proline; Protein Binding; RNA Interference; Seedlings; Solanum lycopersicum; Stress, Physiological | 2018 |
Rational modification of tricarboxylic acid cycle for improving L-lysine production in Corynebacterium glutamicum.
Topics: Batch Cell Culture Techniques; Biomass; Biotin; Carbon; Citric Acid Cycle; Corynebacterium glutamicum; Fermentation; Gene Deletion; Glutamate Dehydrogenase; Glutamic Acid; Lysine; Metabolic Engineering; Oxaloacetic Acid | 2018 |
Chlorpyrifos oxon promotes tubulin aggregation via isopeptide cross-linking between diethoxyphospho-Lys and Glu or Asp: Implications for neurotoxicity.
Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Aspartic Acid; Chlorpyrifos; Cholinesterase Inhibitors; Cross-Linking Reagents; Crystallography, X-Ray; Glutamic Acid; Lysine; Models, Molecular; Neurotoxicity Syndromes; Peptides; Phosphorylation; Protein Aggregates; Swine; Tubulin; Tyrosine | 2018 |
Lysine glycation of apolipoprotein A-I impairs its anti-inflammatory function in type 2 diabetes mellitus.
Topics: Aged; Amino Acid Substitution; Analysis of Variance; Apolipoprotein A-I; Chromatography, Liquid; Diabetes Mellitus, Type 2; Glucose; Glutamic Acid; Glycosylation; Humans; Inflammation; Interleukin-1beta; Lipopolysaccharides; Lipoproteins, HDL; Lysine; Middle Aged; NF-kappa B; Protein Conformation; Protein Disulfide-Isomerases; Tandem Mass Spectrometry; THP-1 Cells; Tumor Necrosis Factor-alpha | 2018 |
Histone Tail Sequences Balance Their Role in Genetic Regulation and the Need To Protect DNA against Destruction in Nucleosome Core Particles Containing Abasic Sites.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; DNA; DNA Cleavage; Glutamic Acid; Histidine; Histones; Humans; Lysine; Mice; Mutation; Nucleosomes; Saccharomyces cerevisiae; Xenopus laevis | 2019 |
Expressing a Monomeric Organophosphate Hydrolase as an EK Fusion Protein.
Topics: Catalytic Domain; Cloning, Molecular; Escherichia coli; Glutamic Acid; Kinetics; Lysine; Models, Molecular; Phosphoric Monoester Hydrolases; Protein Multimerization; Recombinant Fusion Proteins; Substrate Specificity | 2018 |
Thermodynamic characterization for the denatured state of bovine prion protein and the BSE Associated variant E211K.
Topics: Amino Acid Substitution; Animals; Cattle; Encephalopathy, Bovine Spongiform; Glutamic Acid; Humans; Lysine; Prion Proteins; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; Thermodynamics | 2018 |
Synthesis and Evaluation of Multifunctional Fluorescent Inhibitors with Synergistic Interaction of Prostate-Specific Membrane Antigen and Hypoxia for Prostate Cancer.
Topics: Animals; Antigens, Surface; Cell Hypoxia; Cell Line, Tumor; Female; Fluorescent Dyes; Glutamate Carboxypeptidase II; Glutamic Acid; Heterografts; Humans; Lysine; Male; Mice; Mice, Inbred BALB C; Prostatic Neoplasms; Tissue Distribution; Urea | 2019 |
Peptide nucleic acid and amino acid modified peptide nucleic acid analysis by capillary zone electrophoresis.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Glutamic Acid; Hydrogen-Ion Concentration; Limit of Detection; Lysine; Peptide Nucleic Acids | 2019 |
Commonalities and differences in extracellular levels of hippocampal acetylcholine and amino acid neurotransmitters during status epilepticus and subsequent epileptogenesis in two rat models of temporal lobe epilepsy.
Topics: Acetylcholine; Amino Acids; Animals; Aspartic Acid; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Female; Glutamic Acid; Hippocampus; Lysine; Microdialysis; Neurotransmitter Agents; Pilocarpine; Rats; Scopolamine; Seizures; Status Epilepticus; Temporal Lobe | 2019 |
Modified insoluble dietary fibers in okara affect body composition, serum metabolic properties, and fatty acid profiles in mice fed high-fat diets: an NMR investigation.
Topics: Adipose Tissue; Alanine; Animals; Blood Glucose; Body Composition; Body Weight; Cholesterol; Choline; Citric Acid; Diet, High-Fat; Dietary Fiber; Fatty Acids; Fatty Acids, Omega-6; Glutamic Acid; Glycerylphosphorylcholine; Glycine max; Inositol; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Succinic Acid; Triglycerides | 2019 |
Engineering Peptide-Based Polyelectrolyte Complexes with Increased Hydrophobicity.
Topics: Circular Dichroism; Drug Delivery Systems; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Lysine; Mass Spectrometry; Peptides; Polyamines; Polyelectrolytes; Polymers; Protein Engineering; Static Electricity | 2019 |
Atypical COL3A1 variants (glutamic acid to lysine) cause vascular Ehlers-Danlos syndrome with a consistent phenotype of tissue fragility and skin hyperextensibility.
Topics: Adult; Aged; Collagen Type III; Ehlers-Danlos Syndrome; Female; Glutamic Acid; Glycine; High-Throughput Nucleotide Sequencing; Humans; Lysine; Male; Middle Aged; Mutation; Pedigree; Phenotype; Skin Abnormalities | 2019 |
In Vivo Imaging of Small Molecular Weight Peptides for Targeted Renal Drug Delivery: A Study in Normal and Polycystic Kidney Diseased Mice.
Topics: Animals; Aquaporin 1; Coloring Agents; Drug Delivery Systems; Drug Design; Epithelium; Glutamic Acid; Humans; Kidney; Kidney Cortex; Kidney Neoplasms; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Lysine; Magnetic Resonance Imaging; Mice; Peptides; Polycystic Kidney Diseases; Tissue Distribution | 2019 |
Re-evaluation of cyanophycin synthesis in Corynebacterium glutamicum and incorporation of glutamic acid and lysine into the polymer.
Topics: Bacterial Proteins; Corynebacterium glutamicum; Glutamic Acid; Lysine; Metabolic Engineering; Peptide Synthases; Recombinant Proteins | 2019 |
Multiple charged amino acids of Plasmodium falciparum SURFIN
Topics: Amino Acids; Erythrocytes; Glutamic Acid; Host-Parasite Interactions; Humans; Lysine; Membrane Proteins; Plasmodium falciparum; Protein Transport; Protozoan Proteins | 2019 |
E46K-like α-synuclein mutants increase lipid interactions and disrupt membrane selectivity.
Topics: alpha-Synuclein; Cell Membrane; Glutamic Acid; Humans; Lipids; Lysine; Mutant Proteins; Mutation | 2019 |
Conserved Glu-47 and Lys-50 residues are critical for UDP-
Topics: Amino Acid Sequence; Animals; Glutamic Acid; Golgi Apparatus; Ion Transport; Lysine; Mice; Models, Molecular; Protein Conformation; Sequence Homology; Sodium-Phosphate Cotransporter Proteins, Type IIc; Uridine Diphosphate N-Acetylglucosamine; Uridine Monophosphate | 2019 |
Application of a humidity-mediated method to remove residual solvent from crystal lattice.
Topics: Crystallization; Glutamic Acid; Humidity; Inosine Monophosphate; Lysine; Methanol; Solvents; X-Ray Diffraction | 2019 |
pH-dependent adsorption of α-amino acids, lysine, glutamic acid, serine and glycine, on TiO
Topics: Adsorption; Glutamic Acid; Glycine; Hydrogen-Ion Concentration; Lysine; Protein Corona; Serine; Titanium | 2019 |
Targeting metabolic driving and intermediate influx in lysine catabolism for high-level glutarate production.
Topics: Biosynthetic Pathways; Escherichia coli; Glutamic Acid; Glutarates; Lysine; Metabolic Engineering; NADP | 2019 |
Exploring and Engineering the Conformational Landscape of Calmodulin through Specific Interactions.
Topics: Calmodulin; Glutamic Acid; Glycine; Lysine; Molecular Dynamics Simulation; Mutation; Protein Conformation; Protein Domains | 2019 |
MMP-8 C-799 T, Lys460Thr, and Lys87Glu variants are not related to risk of cancer.
Topics: Genetic Predisposition to Disease; Glutamic Acid; Humans; Lysine; Matrix Metalloproteinase 8; Neoplasms; Polymorphism, Single Nucleotide; Threonine | 2019 |
Gating control of the cardiac sodium channel Nav1.5 by its β3-subunit involves distinct roles for a transmembrane glutamic acid and the extracellular domain.
Topics: Animals; Gene Expression Regulation; Glutamic Acid; Humans; Ion Channel Gating; Kinetics; Lysine; Membrane Potentials; Mutagenesis; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Oocytes; Patch-Clamp Techniques; Protein Domains; Protein Structure, Secondary; Xenopus | 2019 |
UV-Visible Lysine-Glutamate Dimer Excitations in Protein Charge Transfer Spectra: TDDFT Descriptions Using an Optimally Tuned CAM-B3LYP Functional.
Topics: Density Functional Theory; Energy Transfer; Glutamic Acid; Lysine; Models, Molecular; Oligopeptides; Protein Conformation; Spectrophotometry, Ultraviolet | 2019 |
The impact of different mutations at arginine141 on the structure, subunit exchange dynamics and chaperone activity of Hsp16.3.
Topics: Alanine; Amino Acid Substitution; Arginine; Bacterial Proteins; Binding Sites; Chaperonins; Glutamic Acid; Hydrophobic and Hydrophilic Interactions; Lactalbumin; Lysine; Mycobacterium tuberculosis; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Structure, Tertiary; Protein Subunits; Serine; Static Electricity; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2020 |
Metabolic characterisation of eight Escherichia coli strains including "Big Six" and acidic responses of selected strains revealed by NMR spectroscopy.
Topics: Acids; Amino Acids; Carboxy-Lyases; Escherichia coli; Escherichia coli O157; Glutamic Acid; Lysine; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Metabolomics; Stress, Physiological | 2020 |
Peptide KE in Human Proteome.
Topics: Amino Acid Sequence; Cytokines; Databases, Protein; Glutamic Acid; Hormones; Humans; Lysine; Nuclear Proteins; Peptides; Proteome; Sequence Analysis, Protein | 2020 |
Enantiomeric determination of econazole and sulconazole by electrokinetic chromatography using hydroxypropyl-β-cyclodextrin combined with ionic liquids based on L-lysine and L-glutamic acid.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Chromatography, Micellar Electrokinetic Capillary; Econazole; Glutamic Acid; Imidazoles; Ionic Liquids; Lysine; Quaternary Ammonium Compounds; Stereoisomerism; Temperature; Time Factors | 2020 |
Left ventricular non compaction and septal defects.
Topics: Amino Acid Substitution; Dystrophin-Associated Proteins; Female; Glutamic Acid; Heart Defects, Congenital; Heart Septal Defects, Atrial; Heart Ventricles; Humans; Lysine; Mutation, Missense; Neuropeptides; Young Adult | 2020 |
Removal of the root canal smear layer using Carisolv III and sodium hypochlorite.
Topics: Adult; Dental Pulp Cavity; Female; Glutamic Acid; Humans; In Vitro Techniques; Incisor; Leucine; Lysine; Male; Middle Aged; Root Canal Irrigants; Root Canal Therapy; Sodium Hypochlorite | 2020 |
Effect of conjugated (EK)
Topics: Allosteric Regulation; Glutamic Acid; Lysine; Molecular Dynamics Simulation; Peptides; Protein Structure, Secondary; Ubiquitin | 2020 |
Zwitterionic Peptide Cloak Mimics Protein Surfaces for Protein Protection.
Topics: Glutamic Acid; Lysine; Peptides; Proteins; Surface Properties | 2020 |
Structures and pH-sensing mechanism of the proton-activated chloride channel.
Topics: Anions; Binding Sites; Chloride Channels; Chlorides; Cryoelectron Microscopy; Glutamic Acid; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Transport; Lysine; Models, Molecular; Patch-Clamp Techniques; Protein Subunits; Protons; Rotation; Single Molecule Imaging; Substrate Specificity | 2020 |
Polyamines Mediate Folding of Primordial Hyperacidic Helical Proteins.
Topics: Amino Acid Substitution; Circular Dichroism; Glutamic Acid; Hydrogen-Ion Concentration; Lysine; Nuclear Magnetic Resonance, Biomolecular; Polyamines; Protein Folding; Proteins | 2020 |
The growth of Arabidopsis primary root is repressed by several and diverse amino acids through auxin-dependent and independent mechanisms and MPK6 kinase activity.
Topics: Amino Acids; Arabidopsis; Arabidopsis Proteins; Glutamic Acid; Indoleacetic Acids; Leucine; Lysine; Mitogen-Activated Protein Kinases; Plant Growth Regulators; Plant Root Cap; Plant Roots; Seedlings; Tryptophan | 2021 |
Spontaneous protein-protein crosslinking at glutamine and glutamic acid residues in long-lived proteins.
Topics: Cataract; Eye Proteins; Glutamic Acid; Glutamine; Humans; Lens, Crystalline; Lysine; Middle Aged; Piperidones; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Young Adult | 2021 |
An Unsual Cys-Glu-Lys Catalytic Triad is Responsible for the Catalytic Mechanism of the Nitrilase Superfamily: A QM/MM Study on Nit2.
Topics: Aminohydrolases; Animals; Biocatalysis; Cysteine; Density Functional Theory; Glutamic Acid; Lysine; Mice; Models, Molecular | 2021 |
Clinical and Histopathological Features of Gelsolin Amyloidosis Associated with a Novel
Topics: Adult; Aged; Amyloid Neuropathies, Familial; Amyloidosis; Amyloidosis, Familial; Corneal Diseases; Corneal Dystrophies, Hereditary; Exome; Family Health; Female; Fundus Oculi; Gelsolin; Genetic Association Studies; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Mutation; Optic Nerve; Optic Nerve Diseases; Phenotype; Protein Folding; Tomography, Optical Coherence | 2021 |
Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes.
Topics: Adult; Aged; Betaine; Biomarkers; Carnitine; Case-Control Studies; Diabetes Mellitus, Type 2; Early Diagnosis; Female; Genetic Predisposition to Disease; Glutamic Acid; Humans; Leucine; Lysine; Male; Mannose; Mendelian Randomization Analysis; Metabolome; Middle Aged; Valine | 2021 |
Development of Nonfouling Zwitterionic Copolymerized Peptides Based on Glutamic Acid and Lysine Dimers for Adjustable Enzymatic Degradation.
Topics: Glutamic Acid; Lysine; Peptides; Polymers; Trypsin | 2021 |
Synthesis of KUE-siRNA Conjugates for Prostate Cancer Cell-Targeted Gene Silencing.
Topics: Antigens, Surface; Gene Silencing; Glutamate Carboxypeptidase II; Glutamic Acid; Humans; Lysine; Male; Prostatic Neoplasms; RNA, Small Interfering; Urea | 2021 |
Effects of supplementation of graded level of glutamic acid to crude protein reduced diets on the performance of growing pigs.
Topics: Animal Feed; Animals; Body Composition; Body Weight; Diet; Diet, Protein-Restricted; Dietary Supplements; Glutamic Acid; Lysine; Swine | 2022 |
Human neocortical expansion involves glutamatergic neuron diversification.
Topics: Alzheimer Disease; Animals; Cell Shape; Collagen; Electrophysiology; Extracellular Matrix Proteins; Female; Glutamic Acid; Humans; Lysine; Male; Mice; Neocortex; Neurons; Patch-Clamp Techniques; Transcriptome | 2021 |
Self-assembled PEGylated amphiphilic polypeptides for gene transfection.
Topics: Animals; Biocompatible Materials; Cell Line; Cell Survival; DNA; Electrophoresis, Agar Gel; Gene Transfer Techniques; Glutamic Acid; Humans; Lysine; Mice; Nanoparticles; Peptides; Polyethylene Glycols; Transfection | 2021 |
Genome editing of Corynebacterium glutamicum mediated with Cpf1 plus Ku/LigD.
Topics: Corynebacterium glutamicum; CRISPR-Cas Systems; DNA End-Joining Repair; Gene Editing; Gene Knockout Techniques; Genome, Bacterial; Glutamic Acid; Ku Autoantigen; Lysine; Metabolic Engineering; Mycobacterium tuberculosis | 2021 |
A mechanism for hereditary angioedema caused by a lysine 311-to-glutamic acid substitution in plasminogen.
Topics: Angioedemas, Hereditary; Animals; Bradykinin; Factor XIIa; Fibrinolysin; Glutamic Acid; Humans; Kininogens; Lysine; Mammals; Mice; Plasma Kallikrein; Plasminogen; Tissue Plasminogen Activator | 2022 |
Bradykinin formation by mutant plasminogen.
Topics: Angioedemas, Hereditary; Bradykinin; Fibrinolysis; Glutamic Acid; Humans; Lysine; Plasminogen | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Improving the Antimicrobial Performance of Amphiphilic Cationic Antimicrobial Peptides Using Glutamic Acid Full-Scan and Positive Charge Compensation Strategies.
Topics: Adenosine Monophosphate; Animals; Anti-Bacterial Agents; Antimicrobial Peptides; Bacteria; Glutamic Acid; Lysine; Mice; Microbial Sensitivity Tests | 2022 |
Core-shell Au-Ag nanoparticles as colorimetric sensing probes for highly selective detection of a dopamine neurotransmitter under different pH conditions.
Topics: Colorimetry; Dopamine; Epinephrine; Glucose; Glutamic Acid; Gold; Humans; Hydrogen-Ion Concentration; Lysine; Metal Nanoparticles; Neurotransmitter Agents; Norepinephrine; Silver | 2022 |
Comparison of amino acid digestibility and its additivity determined with slaughter or cecectomy method for yellow-feather chicken.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Chickens; Diet; Digestion; Feathers; Glutamic Acid; Glycine; Glycine max; Histidine; Ileum; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Valine; Zea mays | 2022 |
A lysine residue from an extracellular turret switches the ion preference in a Cav3 T-Type channel from calcium to sodium ions.
Topics: Animals; Aspartic Acid; Calcium; Calcium Channels, T-Type; Glutamic Acid; Ions; Lymnaea; Lysine; Sodium | 2022 |
A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in
Topics: Amino Acid Substitution; Animals; Anthelmintics; Binding Sites; Carboxylesterase; Esters; Fasciola hepatica; Glutamic Acid; Ligands; Lysine; Polymorphism, Single Nucleotide; Serine; Xenobiotics | 2022 |
Pancreatic tumor microenvironmental acidosis and hypoxia transform gold nanorods into cell-penetrant particles for potent radiosensitization.
Topics: Acidosis; Animals; Cell Line, Tumor; Glutamic Acid; Gold; Hypoxia; Lysine; Mice; Nanotubes; Neoplasms; Tumor Microenvironment | 2022 |
Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linking.
Topics: Chlorpyrifos; Glutamic Acid; Humans; Lysine; Protein Aggregates; Proteins | 2023 |
Uncovering the Contributions of Charge Regulation to the Stability of Single Alpha Helices.
Topics: Glutamic Acid; Lysine; Protein Conformation; Protein Conformation, alpha-Helical | 2023 |
Bulk Biopolyelectrolyte Complexes from Homopolypeptides: Solid "Salt Bridges".
Topics: Amino Acids; Aspartic Acid; Glutamic Acid; Lysine; Peptides | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Diagonal Interactions between Glutamate and Arginine Analogs with Varying Side-Chain Lengths in a β-Hairpin.
Topics: Arginine; Glutamic Acid; Lysine; Peptides; Protein Folding; Protein Structure, Secondary; Thermodynamics | 2023 |
Alterations in the amino acid profile in patients with papillary thyroid carcinoma with and without Hashimoto's thyroiditis.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Glutamic Acid; Glycine; Hashimoto Disease; Humans; Lysine; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tyrosine | 2023 |
Malondialdehyde enhances PsbP protein release during heat stress in Arabidopsis.
Topics: Arabidopsis; Glutamic Acid; Heat-Shock Response; Lysine; Malondialdehyde | 2023 |
Stabilization of Synthetic Collagen Triple Helices: Charge Pairs and Covalent Capture.
Topics: Aspartic Acid; Collagen; Glutamic Acid; Lysine; Models, Molecular | 2023 |