glutamic acid has been researched along with ibotenic acid in 196 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (22.96) | 18.7374 |
| 1990's | 119 (60.71) | 18.2507 |
| 2000's | 23 (11.73) | 29.6817 |
| 2010's | 6 (3.06) | 24.3611 |
| 2020's | 3 (1.53) | 2.80 |
| Authors | Studies |
|---|---|
| Bigge, CF; Drummond, JT; Humblet, C; Johnson, G; Malone, TC; Ortwine, DF; Pinter, GW | 1 |
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ | 1 |
| Arena, JP; Cully, DF; Liu, KK; Paress, PS; Schaeffer, JM | 1 |
| Cox, JA; Seeburg, PH; Stein, E; Verdoorn, TA | 1 |
| Ozawa, S; Takeuchi, T; Tsuzuki, K | 1 |
| Jonas, P; Sakmann, B | 1 |
| Maruyama, M; Nakazawa, M; Takeda, K | 1 |
| Barnes, CA; Foster, TC; McNaughton, BL; Rao, G | 1 |
| Bourque, CW; Cunningham, JT; Hu, B; Nissen, R; Renaud, LP | 1 |
| Ormandy, GC | 1 |
| Chuang, DM; Gao, XM; Paul, SM | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Clark, B; Mobbs, P | 1 |
| Andersen, CF; Frandsen, A; Schousboe, A | 1 |
| Baruah, S; Hegwood, TS; Sherman, AD; Waziri, R | 1 |
| Inokuchi, H; Nishi, S; Polosa, C; Yamada, S; Yoshimura, M | 1 |
| Fain, GL; Yazejian, B | 1 |
| Frandsen, A; Schousboe, A | 1 |
| Martin, D; McNamara, JO; Nadler, JV | 1 |
| Carruth, MK; Fairman, RP; Fowler, AA; Leichnetz, GR; Mayer, DJ | 1 |
| Cha, JH; Davis, RE; Wilmot, GR | 1 |
| Kawai, N; Nakajima, T; Robinson, HP; Shimazaki, K; Takenawa, T | 1 |
| Balázs, R; Hack, N; Kumar, KN; Michaelis, E; Resink, A; Van der Valk, JB | 1 |
| Artaud, F; Chéramy, A; Desce, JM; Galli, T; Glowinski, J; Godeheu, G | 2 |
| Parks, TN; Zhou, N | 1 |
| Bleakman, D; Chard, PS; Glaum, SR; Miller, RJ; Rusin, KI | 1 |
| Malmberg, AB; Yaksh, TL | 1 |
| Bertrand, G; Bockaert, J; Gross, R; Loubatières-Mariani, MM; Puech, R | 2 |
| Bonhaus, DW; McNamara, JO | 1 |
| Blazynski, C; Linn, DM; Massey, SC; Redburn, DA | 1 |
| Beal, MF; Finn, SF; Kowall, NW; Mazurek, MF; Swartz, KJ | 1 |
| Gallo, V; Levi, G; Patrizio, M | 1 |
| Mayer, ML; Patneau, DK | 1 |
| Dodd, PR; Johnston, GA; Maddison, JE; Watson, WE | 1 |
| Garcia-Ladona, FJ; Girard, C; Gombos, G; Palacios, JM | 1 |
| Shreve, PE; Uretsky, NJ | 1 |
| Beaton, JA; Monaghan, DT | 1 |
| Connor, JA; Dickinson, MH; Linden, DJ; Smeyne, M | 1 |
| Sapru, H; Sundaram, K | 1 |
| Hatziefthimiou, A; Kouvelas, ED; Mitsacos, A; Mitsaki, E; Plaitakis, A | 1 |
| MacVicar, BA; Tse, FW; Weiss, S | 1 |
| Matsumoto, RR; Walker, JM | 1 |
| Chang, YC; Lee, YH; Leng, CH; Lin, YH | 1 |
| Eybalin, M; Ladrech, S; Puel, JL; Pujol, R | 1 |
| Olney, JW; Pathikonda, M; Snider, WD; Stewart, GR | 1 |
| Garthwaite, J; Southam, E | 1 |
| Hu, GY; Storm, JF | 1 |
| Cai, NS; Erdö, SL; Kiss, B | 1 |
| Hećimović, H; Randić, M; Ryu, PD | 1 |
| Mayer, ML | 1 |
| Audinat, E; Crepel, F; Geoffroy, M; Hamon, B; Kado, RT; Lambolez, B; Rossier, J | 1 |
| Amaya, Y; Hattori, S; Kawamoto, S; Mishina, M; Miyagi, Y; Okuda, K; Onishi, H | 1 |
| Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A | 1 |
| Cha, JH; Drejer, J; Honoré, T; Nielsen, EO; Young, AB | 1 |
| Conn, PJ; Desai, MA | 1 |
| Cunningham, MD; Michaelis, EK | 1 |
| Jones, PG; Roberts, PJ | 1 |
| Gelhard, RE; Insel, TR; Miller, LP | 1 |
| Cox, JA; Felder, CC; Henneberry, RC | 1 |
| Cha, JH; Makowiec, RL; Penney, JB; Young, AB | 1 |
| Butterworth, RF; Cotman, CW; Giguere, JF; Peterson, C | 1 |
| Morrow, C; Murphy, S; Pearce, B | 1 |
| de Belleroche, J; Reed, LJ | 1 |
| Bockaert, J; Dumuis, A; Oomagari, K; Pin, JP; Sebben, M | 1 |
| Burgoyne, RD; Cambray-Deakin, MA; Foster, AC | 1 |
| Alexander, SP; Hill, SJ; Kendall, DA | 1 |
| Albin, RL; Cha, JH; Gilman, S; Makowiec, RL; Young, AB | 1 |
| Adamson, P; Brammer, MJ; Campbell, IC; Hajimohammadreza, I; Meldrum, BS | 1 |
| Heinemann, U; Mudrick, LA | 1 |
| Boos, R; Müller, F; Wässle, H | 1 |
| Chalmers, DT; Dewar, D; Graham, DI; McCulloch, J; Shand, A | 1 |
| Sansom, MS; Usherwood, PN | 1 |
| Murase, K; Randic, M; Ryu, PD | 1 |
| Fonnum, F; Syvertsen, C | 1 |
| Christensen, BN; O'Dell, TJ | 1 |
| O'Dell, TJ | 1 |
| Avola, R; Bruno, V; Condorelli, DF; Ingrao, F; Magri, G; Nicoletti, F | 1 |
| Westerberg, E; Wieloch, TW | 1 |
| Bear, MF; Bowen, WD; Dudek, SM | 1 |
| Beart, PM; Cincotta, M; Summers, RJ | 1 |
| Aldinio, C; Leon, A; Nicoletti, F; Seren, MS; Zanoni, R | 1 |
| Bear, MF; Dudek, SM | 1 |
| Anwyl, R | 1 |
| Gulyás, J; Janáky, R; Kontro, P; Marnela, KM; Oja, SS; Varga, V | 1 |
| Kawai, N; Saito, M | 1 |
| King, AE; Nistri, A; Rovira, C | 1 |
| Giles, D; Usherwood, PN | 1 |
| Cotman, CW; Monaghan, DT; Yao, D | 1 |
| Hansen, SH; Krogsgaard-Larsen, P; Nielsen, EO; Schousboe, A | 1 |
| Coyle, JT; Koller, KJ | 1 |
| Chuang, DM; Costa, E; Iadarola, MJ; Meek, JL; Nicoletti, F; Roth, BL | 1 |
| Cotman, CW; Ganong, AH | 1 |
| Costa, E; Iadarola, MJ; Nicoletti, F; Wroblewski, JT | 1 |
| Cross, A; Skan, W; Slater, P | 1 |
| de Montigny, C; Ouellette, J; Weiss, M | 1 |
| López-Colomé, AM; Somohano, F | 1 |
| Murphy, DE; Snowhill, EW; Williams, M | 1 |
| Cotman, CW; Harris, EW; Stevens, DR | 1 |
| Alho, H; Costa, E; Eva, C; Fadda, E; Nicoletti, F; Wroblewski, JT | 1 |
| Cowburn, RF; Hardy, JA; Roberts, PJ | 1 |
| Henley, JM; Oswald, RE | 1 |
| Errami, M; Nieoullon, A | 1 |
| Arnerić, SP; Meeley, MP; Reis, DJ; Woo, JI | 1 |
| López-Colomé, AM; Roberts, PJ; Somohano, F | 1 |
| Canonico, PL; Drago, F; Nicoletti, F; Pellegrino, C; Scapagnini, U; Valerio, C | 1 |
| Johnson, BG; Schoepp, DD | 2 |
| Coyle, JT; Murphy, TH; Sastre, A; Schnaar, RL | 1 |
| Akaydin, A; Butterfield, DA; Kommor, ML | 1 |
| Shinozaki, H | 1 |
| Honoré, T; Krogsgaard-Larsen, P; Lauridsen, J | 1 |
| Curtis, DR; Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Leah, JD; Peet, MJ | 1 |
| Hansen, JJ; Krogsgaard-Larsen, P; Lauridsen, J; Nielsen, E | 1 |
| Berdichevsky, E; Orrego, F; Riveros, N; Sánchez-Armáss, S | 1 |
| Collingridge, GL; Kehl, SJ; Loo, R; McLennan, H | 1 |
| Kerkut, GA; Mat Jais, AM; Walker, RJ | 1 |
| Contestabile, A; Migani, P; Poli, A; Villani, L | 1 |
| McBean, GJ; Roberts, PJ; Sharif, NA; Thomas, EM | 1 |
| Glowinski, J; Prémont, J; Stella, N; Tencé, M | 1 |
| Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG | 1 |
| Dowling, JE; Grant, GB | 1 |
| Bischoff, F; Ebert, B; Johansen, TN; Krogsgaard-Larsen, P; Madsen, U | 1 |
| Catania, MV; Hollingsworth, Z; Penney, JB; Young, AB | 2 |
| Henley, JM; Hunt, SP; Jenkins, R | 1 |
| Andou, Y; Enomoto, R; Kataoka, K; Mitani, A; Ogita, K; Yoneda, Y | 1 |
| Baudry, M; Hall, RA; Kessler, M; Lynch, G; Massicotte, G | 1 |
| Glaum, SR; Miller, RJ | 1 |
| Alagarsamy, S; Johnson, KM; Lonart, G | 1 |
| Jaarsma, D; Korf, J; Sebens, JB | 1 |
| Matute, C; Miledi, R | 1 |
| Cid, ME; Ortega, A | 1 |
| Bjerkness, L; Choi, DW; Hartley, DM; Kurth, MC; Weiss, JH | 1 |
| Bessho, Y; Nakanishi, S; Nawa, H | 1 |
| Ferrer-Montiel, AV; Montal, M; Planells-Cases, R; Sun, W | 1 |
| Bastian, J | 1 |
| Ambrosini, A; Racagni, G | 1 |
| Boos, R; Schneider, H; Wässle, H | 1 |
| Mayer, ML; Patneau, DK; Vyklicky, L | 1 |
| Dee, MG; Ha, LH; Spears, LC; Stanley, BG | 1 |
| Albin, RL; Kremer, B; Tallaksen-Greene, SJ | 1 |
| Naarala, J; Nykvist, P; Savolainen, K; Tuomala, M | 1 |
| Barrionuevo, G; Fleck, MW; Henze, DA; Palmer, AM | 1 |
| Haldeman, B; Hampson, DR; Mulvihill, ER; Pickering, DS; Suzdak, PD; Thomsen, C | 1 |
| Henry, JL; Radhakrishnan, V | 1 |
| Bau, A; Faarup, P; Foged, C; Kanstrup, A; Suzdak, PD; Thomsen, C | 1 |
| Bigl, V; Rossner, S; Schliebs, R | 1 |
| Bockaert, J; Brabet, I; Curry, K; Gomeza, J; Joly, C; Pin, JP | 1 |
| Bendahan, G; Boatell, ML; Mahy, N | 1 |
| Katsuki, F; Minakami, R; Nakamura, K; Sugiyama, H; Yamamoto, T | 1 |
| Scholz, WK | 1 |
| Hansson, E | 1 |
| Littman, L; Robinson, MB | 1 |
| Rodnight, R; Wofchuk, ST | 1 |
| Aronica, E; Balázs, R; Condorelli, DF; Nicoletti, F | 1 |
| Glatt, BS; Littman, L; Robinson, MB | 1 |
| Legutko, B; Pilc, A | 1 |
| Hicks, J; Kalivas, PW; Morgan, ZR; Pierce, RC; Reeder, DC | 1 |
| Browne, SE; Everitt, BJ; McCulloch, J; Muir, JL; Page, KJ; Robbins, TW | 1 |
| Evrard, P; Gressens, P; Lamboley, G | 1 |
| Kato, BM; Rubel, EW | 1 |
| Becker, A; Bogerts, B; Grecksch, G; Hoellt, V; Schroeder, H | 1 |
| Mele, A; Oliverio, A; Roullet, P; Sargolini, F | 1 |
| Lapied, B; Raymond, V; Sattelle, DB | 1 |
| Barbanel, G; Cambonie, G; Kamenka, JM; Laplanche, L | 1 |
| Banke, TG; Christensen, JK; Greenwood, JR; Liljefors, T; Pickering, DS; Schousboe, A; Traynelis, SF | 1 |
| Egan, JM; Greig, NH; Haughey, NJ; Mattson, MP; Perry, T | 1 |
| During, MJ; Fitzsimons, HL; Kaplitt, MG; Liu, Y; Luo, J; Oshinsky, ML; Zuzga, DS | 1 |
| Mercier, AJ; Richardson, R; Sammahin, M; Wrong, AD | 1 |
| Ishige, K; Ito, M; Ito, Y; Saito, H; Takagi, N | 1 |
| Li, Y; Owyang, C; Wu, X; Yan, J; Zhu, J | 1 |
| Alberati, D; Borroni, E; Heitz, MP; Kew, J; Le Pen, G; Moreau, JL | 1 |
| Koch, M; Schwabe, K | 1 |
| Ebert, B; Madsen, U; Vestergaard, HT; Vogensen, SB | 1 |
| Bräuner-Osborne, H; Greenwood, JR; Hermit, MB | 1 |
| Begtrup, M; Bräuner-Osborne, H; Calí, P; Clausen, RP; Egebjerg, J; Greenwood, JR; Hansen, KB; Nielsen, B | 1 |
| Dudel, J | 1 |
| Arzimanoglou, A; Baud, O; Gressens, P; Sfaello, I | 1 |
| Gorna, A; Gressens, P; Griesmaier, E; Keller, M; Sarkozy, G; Simbruner, G; Urbanek, M; Yang, J | 1 |
| Aou, S; Ibayashi, S; Iida, M; Kamouchi, M; Katafuchi, T; Kitazono, T; Ooboshi, H; Ota, K; Yamashita, Y | 1 |
| Achaval, M; Biasibetti, R; de Almeida, LM; de Oliveira, LF; Gonçalves, CA; Gottfried, C; Leite, MC; Quillfeldt, JA; Rodrigues, L; Swarowsky, A | 1 |
| Beninger, RJ; Boegman, RJ; Forsyth, JK; Giles, A; Jhamandas, K; Tuerke, KJ; Xue, L | 1 |
| Hirose, K; Iinuma, S; Ito, E; Kobayashi, S; Matsuo, R; Namiki, S; Sakamoto, H; Watanabe, S | 1 |
| Dafny, N; Swann, AC; Wanchoo, SJ | 1 |
| Gratton, A; Lupinsky, D; Moquin, L | 1 |
| Chandler, LJ; Gorelova, N; Mulholland, PJ; Seamans, JK | 1 |
| Inoue, T; Murayama, N; Nakamura, S; Noshita, T; Ogino, R; Oka, T | 1 |
| Bhardwaj, SK; Ryan, R; Srivastava, LK; Tse, YC; Wong, TP | 1 |
| Griesmaier, E; Hermann, M; Kiechl-Kohlendorfer, U; Obermair, GJ; Posod, A; Stanika, RI; Urbanek, M; Wechselberger, K; Wegleiter, K | 1 |
| Ausseil, J; Cleren, C; Daher, I; Daumas, S; Dourmap, N; El Mestikawy, S; Gomila, C; Gonzalez, B; Le Dieu-Lugon, B; Lecuyer, M; Leroux, P; Leroux-Nicollet, I; Marret, S; Ramet, L; Roy, V | 1 |
| Ciric, D; Foretz, M; Isakovic, A; Jovanovic, M; Korolchuk, VI; Markovic, I; Martinovic, T; Misirkic, M; Rabanal-Ruiz, Y; Saponjic, J; Trajkovic, V; Vucicevic, L | 1 |
| Müller, M; Obermaier, S | 1 |
| Chen, ZK; Dong, H; Huang, ZL; Jiang, SY; Li, RX; Ni, J; Qu, WM; Wang, TX; Yuan, MY | 1 |
3 review(s) available for glutamic acid and ibotenic acid
| Article | Year |
|---|---|
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
Single-channel studies of glutamate receptors.
Topics: Animals; Anions; Astacoidea; Cations, Divalent; Electrophysiology; Glutamates; Glutamic Acid; Glycine; Grasshoppers; Hippocampus; Ibotenic Acid; Invertebrates; Ion Channel Gating; Kainic Acid; Membrane Potentials; Models, Biological; N-Methylaspartate; Neuromuscular Junction; Neurotransmitter Agents; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Synaptic Transmission; Vertebrates | 1990 |
Recent advances in the use of selective neuron-destroying agents for neurobiological research.
Topics: Animals; Aziridines; Choline; Colchicine; Folic Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Lectins; Mitogens; Mustard Compounds; Nerve Degeneration; Nervous System; Neurons; Piperidines; Pyrrolidonecarboxylic Acid; Quinolinic Acid; Quinolinic Acids | 1984 |
193 other study(ies) available for glutamic acid and ibotenic acid
| Article | Year |
|---|---|
Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists.
Topics: Binding, Competitive; Isoquinolines; Models, Molecular; Molecular Conformation; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1992 |
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.
Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection | 2000 |
Expression of a glutamate-activated chloride current in Xenopus oocytes injected with Caenorhabditis elegans RNA: evidence for modulation by avermectin.
Topics: Animals; Anthelmintics; Caenorhabditis elegans; Cell Membrane Permeability; Chloride Channels; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Ivermectin; Membrane Proteins; Microinjections; Oocytes; Poly A; RNA; Xenopus laevis | 1992 |
Complex pharmacological properties of recombinant alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subtypes.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Quinoxalines; Receptors, AMPA; Receptors, Neurotransmitter; Recombinant Proteins; Xenopus laevis | 1992 |
Agonist- and subunit-dependent potentiation of glutamate receptors by a nootropic drug aniracetam.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Drug Synergism; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Membrane Potentials; Oocytes; Psychotropic Drugs; Pyrrolidinones; Rats; Receptors, Glutamate; Xenopus laevis | 1992 |
Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane Permeability; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Transport; Kainic Acid; Pyramidal Tracts; Rats; Receptors, Glutamate | 1992 |
Evidence that [3H]glutamate binding sites are masked by biologically relevant endogenous factor on cell membranes of frog spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cytosol; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Membrane Potentials; N-Methylaspartate; Piperazines; Quisqualic Acid; Rana catesbeiana; Spinal Cord | 1992 |
Region-specific age effects on AMPA sensitivity: electrophysiological evidence for loss of synaptic contacts in hippocampal field CA1.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Models, Neurological; Nerve Fibers; Neurons; Pyramidal Tracts; Rats; Synapses | 1992 |
Rat supraoptic neurons are resistant to glutamate neurotoxicity.
Topics: Animals; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Neurons; Osmolar Concentration; Rats; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus | 1992 |
Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in rat hippocampus by L-aspartate-beta-hydroxamate.
Topics: Animals; Asparagine; Carbachol; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1992 |
N-methyl-D-aspartate exposure blocks glutamate toxicity in cultured cerebellar granule cells.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebellum; Culture Media; Cytoplasmic Granules; Excitatory Amino Acid Antagonists; Glucose; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Ouabain; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sensitivity and Specificity; Tritium | 1992 |
N-methyl-D-aspartic acid (NMDA) and non-NMDA receptors regulating hippocampal norepinephrine release. I. Location on axon terminals and pharmacological characterization.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Axons; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptosomes | 1992 |
Transmitter-operated channels in rabbit retinal astrocytes studied in situ by whole-cell patch clamping.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Bicuculline; Chloride Channels; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Ion Channels; Kainic Acid; Kinetics; Membrane Potentials; Membrane Proteins; Quisqualic Acid; Rabbits; Receptors, GABA-A; Retina; Time Factors | 1992 |
Possible role of cGMP in excitatory amino acid induced cytotoxicity in cultured cerebral cortical neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Cholera Toxin; Cyclic GMP; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Neurons; Pertussis Toxin; Quisqualic Acid; Time Factors; Virulence Factors, Bordetella | 1992 |
Presynaptic modulation of amino acid release from synaptosomes.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Brain; Calcium; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Male; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Rats, Inbred Strains; Synapses; Synaptosomes | 1992 |
Fast excitatory postsynaptic potentials and the responses to excitant amino acids of sympathetic preganglionic neurons in the slice of the cat spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Evoked Potentials; Ganglia, Sympathetic; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1992 |
Excitatory amino acid receptors on isolated retinal ganglion cells from the goldfish.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cells, Cultured; Chlorides; Electrophysiology; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retinal Ganglion Cells; Sodium | 1992 |
Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neu
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Dantrolene; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Neurotoxins; Quisqualic Acid; Verapamil | 1992 |
Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kindling, Neurologic; Magnesium; Male; N-Methylaspartate; Neurons; Rats; Rats, Inbred Strains | 1992 |
Respiratory failure without pulmonary edema following injection of a glutamate agonist into the ventral medullary raphe of the rat.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Body Temperature; Bronchoalveolar Lavage Fluid; Drug Interactions; Glutamates; Glutamic Acid; Ibotenic Acid; Injections; Lung; Male; Medulla Oblongata; Models, Biological; Pulmonary Edema; Pulmonary Wedge Pressure; Rats; Rats, Inbred Strains; Respiratory Insufficiency; Staining and Labeling | 1992 |
Glutamic acid-insensitive [3H]kainic acid binding in goldfish brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; Ligands; Neurotoxins; Tissue Distribution; Tritium | 1992 |
Purification of AMPA type glutamate receptor by a spider toxin.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cattle; Cerebellum; Chloride Channels; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Liposomes; Membrane Proteins; N-Methylaspartate; Nerve Tissue Proteins; Quisqualic Acid; Receptors, AMPA; Receptors, Neurotransmitter; Spider Venoms | 1992 |
NMDA treatment and K(+)-induced depolarization selectively promote the expression of an NMDA-preferring class of the ionotropic glutamate receptors in cerebellar granule neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cell Survival; Cells, Cultured; Cerebellar Cortex; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Magnesium; N-Methylaspartate; Neurons; Potassium; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Up-Regulation | 1992 |
L-glutamate-evoked release of dopamine from synaptosomes of the rat striatum: involvement of AMPA and N-methyl-D-aspartate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Stimulation, Chemical; Synaptosomes | 1992 |
Gamma-D-glutamylaminomethyl sulfonic acid (GAMS) distinguishes subtypes of glutamate receptor in the chick cochlear nucleus (nuc. magnocellularis).
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Chickens; Cochlea; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Kainic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Metabotropic glutamate receptors potentiate ionotropic glutamate responses in the rat dorsal horn.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Drug Synergism; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channel Gating; Kainic Acid; Myocardial Contraction; N-Methylaspartate; Neurons; Rats; Receptors, Glutamate; Receptors, Neurotransmitter; Spinal Cord; Synapses; Synaptic Transmission | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hyperalgesia; Ibotenic Acid; Injections, Spinal; N-Methylaspartate; Prostaglandin-Endoperoxide Synthases; Quinoxalines; Receptors, Neurokinin-1; Receptors, Neurotransmitter; Receptors, Tachykinin; Substance P | 1992 |
Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Insulin; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Tetrodotoxin | 1992 |
Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Culture Techniques; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Ion Channels; Kainic Acid; N-Methylaspartate; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1992 |
Acetylcholine release from the rabbit retina mediated by kainate receptors.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Choline; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Quisqualic Acid; Rabbits; Receptors, Kainic Acid; Receptors, Neurotransmitter; Retina | 1991 |
Neurochemical characterization of excitotoxin lesions in the cerebral cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; NADPH Dehydrogenase; Neuropeptides; Neurotoxins; Neurotransmitter Agents; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains | 1991 |
Release of endogenous and newly synthesized glutamate and of other amino acids induced by non-N-methyl-D-aspartate receptor activation in cerebellar granule cell cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcium; Cells, Cultured; Cerebellum; Exocytosis; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Potassium; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Taurine | 1991 |
Kinetic analysis of interactions between kainate and AMPA: evidence for activation of a single receptor in mouse hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Electrophysiology; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Mice; Neurons; Quisqualic Acid; Receptors, Kainic Acid; Receptors, Neurotransmitter | 1991 |
Alterations in cortical [3H]kainate and alpha-[3H]amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding in a spontaneous canine model of chronic hepatic encephalopathy.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Chronic Disease; Dizocilpine Maleate; Dogs; Glutamates; Glutamic Acid; Hepatic Encephalopathy; Ibotenic Acid; Kainic Acid; Ligands; Tritium | 1991 |
Autoradiographic characterization of [3H]L-glutamate binding sites in developing mouse cerebellar cortex.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Binding, Competitive; Calcium; Cerebellar Cortex; Chlorides; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Mice; N-Methylaspartate; Protein Binding; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses | 1991 |
GABA and glutamate interact in the substantia innominata/lateral preoptic area to modulate locomotor activity.
Topics: 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Ibotenic Acid; Male; Motor Activity; Muscimol; N-Methylaspartate; Picrotoxin; Preoptic Area; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Quinolinate differentiates between forebrain and cerebellar NMDA receptors.
Topics: Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kinetics; N-Methylaspartate; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
A long-term depression of AMPA currents in cultured cerebellar Purkinje neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; Purkinje Cells; Receptors, Amino Acid; Receptors, Cell Surface; Time Factors | 1991 |
NMDA receptors in the intermediolateral column of the spinal cord mediate sympathoexcitatory cardiac responses elicited from the ventrolateral medullary pressor area.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Convulsants; Glutamates; Glutamic Acid; Heart Rate; Ibotenic Acid; Kainic Acid; Male; Medulla Oblongata; Microinjections; Myocardial Contraction; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1991 |
Quantitative autoradiographic study of L-glutamate binding sites in normal and atrophic human cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Male; N-Methylaspartate; Olivopontocerebellar Atrophies; Piperazines; Quinoxalines; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Quisqualate agonists occlude kainate-induced current in cultured striatal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cells, Cultured; Corpus Striatum; Drug Interactions; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Neurons; Quisqualic Acid | 1991 |
Inhibition of rubral neurons by noxious and non-noxious pressure.
Topics: Animals; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hindlimb; Ibotenic Acid; Male; Microinjections; Morphine; Neurons; Oxotremorine; Pain; Pressure; Rats; Rats, Inbred Strains; Red Nucleus; Serotonin; Tail | 1991 |
Solubilization, characterization, and partial purification of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-, quisqualate-, kainate-sensitive L-glutamate binding sites from porcine brain synaptic junctions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Chromatography; Detergents; Glutamates; Glutamic Acid; Hot Temperature; Ibotenic Acid; Kainic Acid; Octoxynol; Polyethylene Glycols; Quisqualic Acid; Solubility; Synapses | 1991 |
Presynaptic facilitation of dopamine release through D,L-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors on synaptosomes from the rat striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Corpus Striatum; Dipeptides; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Nerve Endings; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptosomes; Tritium | 1991 |
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid electrophysiological and neurotoxic effects in the guinea-pig cochlea.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cochlear Microphonic Potentials; Dendrites; Female; Glutamates; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Ibotenic Acid; Male; Quinoxalines; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synaptic Transmission; Vestibulocochlear Nerve | 1991 |
Excitotoxicity in the embryonic chick spinal cord.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Animals; beta-Alanine; Chick Embryo; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Quinoxalines; Quisqualic Acid; Spinal Cord | 1991 |
Intercellular action of nitric oxide in adult rat cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Drug Interactions; Glutamates; Glutamic Acid; Hemoglobins; Hydroxylamine; Hydroxylamines; Ibotenic Acid; Kainic Acid; Molsidomine; N-Methylaspartate; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; S-Nitroso-N-Acetylpenicillamine | 1991 |
Excitatory amino acids acting on metabotropic glutamate receptors broaden the action potential in hippocampal neurons.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Female; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Neurons; Phorbol Esters; Pyramidal Tracts; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1991 |
Vinpocetine preferentially antagonizes quisqualate/AMPA receptor responses: evidence from release and ligand binding studies.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dopamine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; Membranes; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tritium; Vinca Alkaloids | 1991 |
Substance P modulates glutamate-induced currents in acutely isolated rat spinal dorsal horn neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Neurons; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance P | 1990 |
Glutamate: three meetings but how many receptors? Excitatory Amino Acids 1990: a Fidia Research Foundation Symposium, Padua, Italy, May 21-26, 1990. Excitatory Amino Acid Receptors in the Brain: Functions and Disorders, Montreal, Canada, June 23-24, 1990.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; GTP-Binding Proteins; Ibotenic Acid; Ion Channel Gating; Ion Channels; Kainic Acid; N-Methylaspartate; Neurotransmitter Agents; Quisqualic Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Signal Transduction | 1990 |
Reduction of desensitization of a glutamate ionotropic receptor by antagonists.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glutamates; Glutamic Acid; Ibotenic Acid; Ion Channels; Membrane Potentials; Oocytes; Purkinje Cells; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Xenopus | 1991 |
Functional expression of the alpha 1 subunit of the AMPA-selective glutamate receptor channel, using a baculovirus system.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baculoviridae; DNA, Recombinant; Gene Expression; Genetic Vectors; Glutamates; Glutamic Acid; Ibotenic Acid; Insecta; Ion Channels; Kainic Acid; Kinetics; Mice; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Transfection | 1991 |
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Cerebellum; Dihydropyridines; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Isradipine; Kainic Acid; Nerve Degeneration; Nervous System Diseases; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Autoradiographic characterization and localization of quisqualate binding sites in rat brain using the antagonist [3H]6-cyano-7-nitroquinoxaline-2,3-dione: comparison with (R,S)-[3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding sites.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Oxadiazoles; Oxazoles; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
Selective activation of phosphoinositide hydrolysis by a rigid analogue of glutamate.
Topics: Amino Acids; Animals; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains | 1990 |
Solubilization and partial purification of 3-((+-)-2-carboxypiperazine-4-yl)-[1,2-3H]propyl-1-phosphonic acid recognition proteins from rat brain synaptic membranes.
Topics: Animals; Brain Chemistry; Cholic Acids; Chromatography, Affinity; Edetic Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Magnesium; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Solubility; Synaptic Membranes | 1990 |
Ibotenate stimulates glutamate release from guinea pig cerebrocortical synaptosomes: inhibition by L-2-amino-4-phosphonobutyrate (L-AP4).
Topics: Aminobutyrates; Animals; Cerebral Cortex; Female; Glutamates; Glutamic Acid; Guinea Pigs; Ibotenic Acid; In Vitro Techniques; Male; Neurotoxins; Neurotransmitter Agents; Oxazoles; Synaptosomes | 1990 |
The ontogeny of excitatory amino acid receptors in rat forebrain--I. N-methyl-D-aspartate and quisqualate receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Frontal Lobe; Glutamates; Glutamic Acid; Ibotenic Acid; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Differential expression of excitatory amino acid receptor subtypes in cultured cerebellar neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Cerebellum; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; N-Methylaspartate; Neurons; Oxadiazoles; Potassium Chloride; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
L-[3H]glutamate labels the metabotropic excitatory amino acid receptor in rodent brain.
Topics: Animals; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Neurotransmitter Agents; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Selective loss of N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain following portacaval anastomosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ammonia; Animals; Aspartic Acid; Brain; Cerebral Cortex; Corpus Striatum; Down-Regulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Liver; Male; N-Methylaspartate; Organ Size; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Thalamus | 1990 |
Further characterisation of excitatory amino acid receptors coupled to phosphoinositide metabolism in astrocytes.
Topics: Astrocytes; Cells, Cultured; Glutamates; Glutamic Acid; Ibotenic Acid; Neurotransmitter Agents; Oxadiazoles; Oxazoles; Phosphatidylinositols; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
Induction of ornithine decarboxylase in cerebral cortex by excitotoxin lesion of nucleus basalis: association with postsynaptic responsiveness and N-methyl-D-aspartate receptor activation.
Topics: Animals; Basal Ganglia; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Eflornithine; Enzyme Induction; Excitatory Amino Acid Antagonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxazoles; Pentobarbital; Phosphatidylinositol Phosphates; Phosphatidylinositols; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine; Substantia Innominata; Synapses | 1990 |
Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Cells, Cultured; Corpus Striatum; Cycloleucine; Electrophysiology; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Neurons; Oxadiazoles; Quisqualic Acid; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1990 |
The expression of excitatory amino acid binding sites during neuritogenesis in the developing rat cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cerebellum; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Oxazoles; Rats; Receptors, Amino Acid; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Excitatory amino acid-induced formation of inositol phosphates in guinea-pig cerebral cortical slices: involvement of ionotropic or metabotropic receptors?
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Calcium Chloride; Carbachol; Cerebral Cortex; Cycloleucine; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Oxadiazoles; Oxazoles; Potassium Chloride; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Two types of quisqualate receptors are decreased in human olivopontocerebellar atrophy cerebellar cortex.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Autoradiography; Cerebellar Cortex; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Olivopontocerebellar Atrophies; Oxadiazoles; Receptors, AMPA; Receptors, Neurotransmitter; Reference Values; Spinocerebellar Degenerations; Tritium | 1990 |
Presynaptic glutamate/quisqualate receptors: effects on synaptosomal free calcium concentrations.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Calcium; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Phosphoserine; Quinoxalines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Glutamate; Receptors, Neurotransmitter; Synapses; Synaptosomes | 1990 |
Quisqualate-induced changes in extracellular sodium and calcium concentrations persist in the combined presence of NMDA and non-NMDA receptor antagonists in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Evoked Potentials; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Ketamine; Membrane Potentials; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Sodium | 1990 |
Actions of excitatory amino acids on brisk ganglion cells in the cat retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Anesthesia; Animals; Aspartic Acid; Cats; Electrodes; Glutamates; Glutamic Acid; Ibotenic Acid; Iontophoresis; Kainic Acid; N-Methylaspartate; Photic Stimulation; Quisqualic Acid; Retinal Ganglion Cells | 1990 |
Selective reduction of quisqualate (AMPA) receptors in Alzheimer cerebellum.
Topics: Aged; Aged, 80 and over; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Autoradiography; Cerebellum; Female; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Receptors, AMPA; Receptors, Neurotransmitter | 1990 |
Excitatory and inhibitory amino acids and peptide-induced responses in acutely isolated rat spinal dorsal horn neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Aspartic Acid; Calcitonin Gene-Related Peptide; Drug Synergism; Electric Conductivity; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Neurons; Neuropeptides; Oxadiazoles; Peptides; Quisqualic Acid; Rats; Rats, Inbred Strains; Spinal Cord; Substance P | 1989 |
L-[3H]glutamate binding to a membrane preparation from crayfish muscle.
Topics: Animals; Aspartic Acid; Astacoidea; Binding, Competitive; Calcium; Cell Membrane; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Muscles; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Stereoisomerism | 1989 |
A voltage-clamp study of isolated stingray horizontal cell non-NMDA excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Cell Separation; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Fishes; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Osmolar Concentration; Oxadiazoles; Quisqualic Acid; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1989 |
Pharmacological characterization of voltage-clamped catfish rod horizontal cell responses to kainic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Catfishes; Convulsants; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kinetics; N-Methylaspartate; Oxadiazoles; Photoreceptor Cells; Quisqualic Acid | 1989 |
Activation of excitatory amino acid receptors reduces thymidine incorporation and cell proliferation rate in primary cultures of astrocytes.
Topics: Animals; Astrocytes; Brain; Cell Division; Cells, Cultured; Glutamates; Glutamic Acid; Ibotenic Acid; Oxadiazoles; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Thymidine | 1989 |
Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Frontal Lobe; Glutamates; Glutamic Acid; Hypoglycemia; Ibotenic Acid; Insulin; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Postnatal changes in glutamate stimulated phosphoinositide turnover in rat neocortical synaptoneurosomes.
Topics: Aging; Cerebral Cortex; Female; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Phosphatidylinositols; Receptors, Amino Acid; Receptors, Cell Surface; Synaptosomes | 1989 |
Biochemical characterization of an autoradiographic method for studying excitatory amino acid receptors using L-[3H]glutamate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding, Competitive; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Male; N-Methylaspartate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter; Software; Tritium | 1989 |
Stimulation of inositol phospholipid hydrolysis by excitatory amino acids is enhanced in brain slices from vulnerable regions after transient global ischemia.
Topics: Animals; Brain; Carbachol; Cerebral Cortex; Corpus Striatum; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; In Vitro Techniques; Inositol Phosphates; Ischemic Attack, Transient; Kinetics; Male; Norepinephrine; Organ Specificity; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Reperfusion | 1989 |
A biochemical correlate of the critical period for synaptic modification in the visual cortex.
Topics: Aging; Animals; Aspartic Acid; Carbachol; Cattle; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Ocular Physiological Phenomena; Phosphatidylinositols; Synapses; Vision, Ocular; Visual Cortex | 1989 |
Early warning for LTP.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Membrane Potentials; Oxadiazoles; Quisqualic Acid; Synapses; Time Factors | 1989 |
Displacement of excitatory amino acid receptor ligands by acidic oligopeptides.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Frontal Lobe; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1989 |
Developmental changes in the glutamate receptor at the insect neuromuscular synapse.
Topics: Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Larva; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission; Tenebrio | 1985 |
The excitation of frog motoneurones in vitro by the glutamate analogue, DI-alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA), and the effect of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Glutamates; Glutamic Acid; Ibotenic Acid; Membrane Potentials; Motor Neurons; Oxadiazoles; Oxazoles; Quisqualic Acid; Rana temporaria; Receptors, AMPA; Receptors, Drug; Spinal Cord; Synapses; Synaptic Transmission; Valine | 1985 |
The effects of putative amino acid neurotransmitters on somata isolated from neurons of the locust central nervous system.
Topics: Action Potentials; Animals; Aspartic Acid; Cysteine; Female; gamma-Aminobutyric Acid; Ganglia; Glutamates; Glutamic Acid; Grasshoppers; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Membrane Potentials; Neurons; Neurotransmitter Agents; Taurine | 1985 |
L-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Chemistry; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1985 |
Excitatory amino acids: studies on the biochemical and chemical stability of ibotenic acid and related compounds.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Decarboxylation; Glutamates; Glutamic Acid; Hot Temperature; Hydrogen-Ion Concentration; Ibotenic Acid; Isoxazoles; Liver; Mice; Muscimol; Oxazoles; Pregnancy Proteins | 1985 |
The characterization of the specific binding of [3H]-N-acetylaspartylglutamate to rat brain membranes.
Topics: Animals; Binding, Competitive; Brain; Calcium; Dipeptides; Glutamates; Glutamic Acid; Guanine Nucleotides; Ibotenic Acid; Kinetics; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Serine; Sodium; Synaptosomes; Tissue Distribution | 1985 |
Coupling of inositol phospholipid metabolism with excitatory amino acid recognition sites in rat hippocampus.
Topics: Animals; Aspartic Acid; Calcium; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Male; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Spinal Cord | 1986 |
Kynurenic acid and quinolinic acid act at N-methyl-D-aspartate receptors in the rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tetrodotoxin | 1986 |
Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors.
Topics: Age Factors; Aminobutyrates; Animals; Aspartic Acid; Drug Interactions; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Norepinephrine; Oxadiazoles; Oxazoles; Phosphatidylinositols; Phosphoserine; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Amino Acid; Receptors, Cell Surface | 1986 |
Binding sites for [3H]glutamate and [3H]aspartate in human cerebellum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aspartic Acid; Binding Sites; Calcium Chloride; Cerebellum; Dicarboxylic Acids; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Oxadiazoles; Quisqualic Acid | 1986 |
Reduced excitatory effect of kainic acid on rat CA3 hippocampal pyramidal neurons following destruction of the mossy projection with colchicine.
Topics: Animals; Colchicine; Denervation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Male; Neurons; Rats; Rats, Inbred Strains; Synaptic Transmission | 1987 |
Characterization of quisqualate-type L-glutamate receptors in the retina.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Aspartic Acid; Binding, Competitive; Chickens; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Ibotenic Acid; Kinetics; Receptors, AMPA; Receptors, Drug; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Subcellular Fractions | 1987 |
Characterization of quisqualate recognition sites in rat brain tissue using DL-[3H]alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) and a filtration assay.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Chemical Phenomena; Chemistry; Filtration; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Oxadiazoles; Oxazoles; Quisqualic Acid; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Drug; Thiocyanates | 1987 |
Hippocampal cells primed with quisqualate are depolarized by AP4 and AP6, ligands for a putative glutamate uptake site.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Aminocaproates; Animals; Aspartic Acid; Electric Stimulation; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Norleucine; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1987 |
Lesions of putative glutamatergic pathways potentiate the increase of inositol phospholipid hydrolysis elicited by excitatory amino acids.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Colchicine; Corpus Striatum; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Oxadiazoles; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface | 1987 |
Characterisation of Na+-independent L-[3H]glutamate binding sites in human temporal cortex.
Topics: 2-Amino-5-phosphonovalerate; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Cell Membrane; Chlorides; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Male; Middle Aged; Oxadiazoles; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium; Temporal Lobe | 1988 |
Characterization and regional distribution of glutamatergic and cholinergic ligand binding sites in goldfish brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Cyprinidae; Glutamates; Glutamic Acid; Goldfish; Ibotenic Acid; Kainic Acid; Ligands; Ocular Physiological Phenomena; Receptors, Cholinergic; Receptors, Glutamate; Receptors, Neurotransmitter; Time Factors | 1988 |
alpha-[3H]Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid binding to rat striatal membranes: effects of selective brain lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Choline O-Acetyltransferase; Corpus Striatum; Denervation; Dopamine; Glutamate Decarboxylase; Glutamates; Glutamic Acid; Ibotenic Acid; Membranes; Oxadiazoles; Oxazoles; Quisqualic Acid; Rats; Rats, Inbred Strains | 1988 |
Spontaneous release of endogenous aspartate and glutamate from rat striatal slices is increased following destruction of local neurons by ibotenic acid.
Topics: Amino Acids; Animals; Aspartic Acid; Corpus Striatum; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Neurons; Oxazoles; Rats | 1988 |
Maturational changes in retinal excitatory amino acid receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Binding, Competitive; Chick Embryo; Embryonic and Fetal Development; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; N-Methylaspartate; Receptors, Amino Acid; Receptors, Cell Surface; Retina | 1988 |
Spatial learning potentiates the stimulation of phosphoinositide hydrolysis by excitatory amino acids in rat hippocampal slices.
Topics: Animals; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Learning; Male; Oxazoles; Phosphatidylinositols; Rats; Rats, Inbred Strains; Space Perception; Stimulation, Chemical | 1988 |
Selective inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in the rat hippocampus by activation of protein kinase C.
Topics: Alkaloids; Amino Acids; Animals; Carbachol; Enzyme Activation; Glutamates; Glutamic Acid; Hippocampus; Homocysteine; Ibotenic Acid; Male; Norepinephrine; Oxadiazoles; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Quisqualic Acid; Rats; Rats, Inbred Strains; Staurosporine | 1988 |
Glutamate cytotoxicity in a neuronal cell line is blocked by membrane depolarization.
Topics: Animals; Cell Line; Glutamates; Glutamic Acid; Hybrid Cells; Ibotenic Acid; Membrane Potentials; Neuroblastoma; Neurons; Neurotoxins; Oxadiazoles; Quisqualic Acid; Retina | 1988 |
Electron spin resonance studies of the effects of naturally-occurring excitotoxic amino acid analogues on the physical state of membrane proteins in human erythrocytes.
Topics: Amino Acids; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; Membrane Proteins; Spin Labels | 1981 |
[Pharmacology of glutamate sensitive synapses (I). Glutamate agonists (author's transl)].
Topics: Action Potentials; Animals; Astacoidea; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Models, Neurological; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Synapses; Synaptic Transmission | 1982 |
The binding of [3H]AMPA, a structural analogue of glutamic acid, to rat brain membranes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Chemical Phenomena; Chemistry; Female; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Ibotenic Acid; Male; Mathematics; Oxazoles; Rats; Rats, Inbred Strains | 1982 |
Glutamic acid agonists. Stereochemical and conformational studies of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and related compounds.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Evoked Potentials; Ganglia, Spinal; Glutamates; Glutamic Acid; Ibotenic Acid; Interneurons; Oxazoles; Spinal Cord; Stereoisomerism; Synaptic Transmission; Valine | 1982 |
Enzymic resolution and binding to rat brain membranes of the glutamic acid agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; Kinetics; Oxazoles; Rats; Stereoisomerism | 1983 |
Kainate, N-methylaspartate and other excitatory amino acids increase calcium influx into rat brain cortex cells in vitro.
Topics: Absorption; Amino Acids; Animals; Aspartic Acid; Calcium; Cerebral Cortex; Glutamates; Glutamic Acid; Homocysteine; Ibotenic Acid; In Vitro Techniques; Kainic Acid; N-Methylaspartate; Rats | 1983 |
Effects of kainic and other amino acids on synaptic excitation in rat hippocampal slices: 1. Extracellular analysis.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Evoked Potentials; Folic Acid; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Male; N-Methylaspartate; Neural Pathways; Oxadiazoles; Pyrrolidines; Quisqualic Acid; Rats | 1983 |
The ionic mechanisms associated with the excitatory response of kainate, L-glutamate, quisqualate, ibotenate, AMPA and methyltetrahydrofolate on leech Retzius cells.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Ganglia; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Leeches; Membrane Potentials; Neurons; Osmolar Concentration; Oxadiazoles; Oxazoles; Pyrrolidines; Quisqualic Acid; Sodium; Tetrahydrofolates | 1984 |
Striatal glutamatergic function: modifications following specific lesions.
Topics: Animals; Binding Sites; Cerebral Cortex; Cerebral Decortication; Corpus Striatum; Female; Glutamates; Glutamic Acid; Hydroxydopamines; Ibotenic Acid; Neural Pathways; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra; Synaptic Transmission | 1982 |
Glutamate-evoked release of arachidonic acid from mouse brain astrocytes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Astrocytes; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Corpus Striatum; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol Phosphates; Kainic Acid; Kinetics; Mice; N-Methylaspartate; Neurotoxins; Organ Specificity; Quisqualic Acid; Receptors, Glutamate; Time Factors; Tritium | 1994 |
Metabotropic glutamate receptor modulation of cAMP accumulation in the neonatal rat hippocampus.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Deaminase; Animals; Animals, Newborn; Colforsin; Cyclic AMP; Cycloleucine; Female; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Neurotoxins; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Glutamate | 1993 |
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction | 1994 |
A glutamate-activated chloride current in cone-driven ON bipolar cells of the white perch retina.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chloride Channels; Chlorides; Cycloleucine; Dendrites; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Perches; Picrotoxin; Quinoxalines; Quisqualic Acid; Receptors, Metabotropic Glutamate; Retina; Retinal Cone Photoreceptor Cells; Strychnine | 1995 |
Excitatory amino acid receptor ligands: asymmetric synthesis, absolute stereochemistry and pharmacology of (R)- and (S)-homoibotenic acid.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Ligands; N-Methylaspartate; Radioligand Assay; Rats; Receptors, Glutamate; Stereoisomerism; Structure-Activity Relationship | 1995 |
Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid | 1993 |
Localisation of glutamate receptor binding sites and mRNAs to the dorsal horn of the rat spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Glutamates; Glutamic Acid; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Neural Pathways; Phencyclidine; Rats; Receptors, Glutamate; RNA, Messenger; Spinal Cord; Substantia Gelatinosa | 1993 |
Binding of [3H]MK-801, NMDA-displaceable [3H]glutamate, [3H]glycine, [3H]spermidine, [3H]kainate and [3H]AMPA to regionally discrete brain membranes of the gerbil: a biochemical study.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Cell Membrane; Dizocilpine Maleate; Female; Gerbillinae; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Receptors, Glutamate; Spermidine; Thiocyanates; Tissue Distribution | 1993 |
Thiocyanate equally increases affinity for two DL-alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid (AMPA) receptor states.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Thiocyanates | 1993 |
Activation of metabotropic glutamate receptors produces reciprocal regulation of ionotropic glutamate and GABA responses in the nucleus of the tractus solitarius of the rat.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Electrophysiology; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Medulla Oblongata; Muscimol; Neurons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Synapses | 1993 |
(R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors mediate a calcium-dependent inhibition of the metabotropic glutamate receptor-stimulated formation of inositol 1,4,5-trisphosphate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cycloleucine; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol 1,4,5-Trisphosphate; N-Methylaspartate; Protein Kinases; Rats; Receptors, AMPA; Receptors, Glutamate | 1993 |
Glutamate dehydrogenase improves binding of [3H]CGP39653 to NMDA receptors in the autoradiographic assay.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Autoradiography; Brain; Brain Chemistry; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Neurotransmitter receptors and voltage-dependent Ca2+ channels encoded by mRNA from the adult corpus callosum.
Topics: Adult; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antisense Elements (Genetics); Aspartic Acid; Astrocytes; Biomarkers; Calcium Channels; Cattle; Corpus Callosum; Female; Glial Fibrillary Acidic Protein; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; In Situ Hybridization; Kainic Acid; Male; Membrane Potentials; Middle Aged; Oocytes; Quisqualic Acid; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Neurotransmitter; RNA Probes; RNA, Messenger; Xenopus | 1993 |
Quisqualate resolves two distinct metabotropic [3H]glutamate binding sites.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Corpus Striatum; Cycloleucine; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid | 1993 |
Glutamate stimulates [3H]phorbol 12,13-dibutyrate binding in cultured Bergmann glia cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cell Membrane; Cells, Cultured; Cerebellum; Chick Embryo; Cytosol; Enzyme Activation; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Neuroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Purkinje Cells | 1993 |
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methylaspartate; Nerve Degeneration; Neurons; Quinoxalines; Receptors, Glutamate | 1993 |
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Kynurenic Acid; Molecular Weight; N-Methylaspartate; Nerve Growth Factors; Nerve Tissue Proteins; Quinoxalines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrodotoxin; Transcription, Genetic | 1993 |
Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Sequence; Animals; Cloning, Molecular; Dizocilpine Maleate; DNA; Female; Frontal Lobe; Gene Library; Glutamates; Glutamic Acid; Glycine; Humans; Ibotenic Acid; Kainic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oocytes; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sequence Homology, Amino Acid; Transcription, Genetic; Xenopus laevis | 1993 |
The role of amino acid neurotransmitters in the descending control of electroreception.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Bicuculline; Dendrites; Electric Stimulation; Electrophysiology; Fishes; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Ibotenic Acid; Microinjections; Neurons; Neurotransmitter Agents; Pyramidal Tracts; Quinoxalines; Sensory Receptor Cells | 1993 |
Glutamate receptor-induced cyclic GMP formation in primary cultures of mesencephalic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Fetus; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Kinetics; Mesencephalon; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phorbol 12,13-Dibutyrate; Quinoxalines; Receptors, Glutamate | 1993 |
Voltage- and transmitter-gated currents of all-amacrine cells in a slice preparation of the rat retina.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Cobalt; Electrophysiology; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kainic Acid; Membrane Potentials; N-Methylaspartate; Potassium Channels; Quinoxalines; Rats; Receptors, Amino Acid; Retina; Retinal Ganglion Cells; Sodium Channels; Strychnine; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1993 |
Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzothiadiazines; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Electrophysiology; Evoked Potentials; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Kainic Acid; Kinetics; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley | 1993 |
Lateral hypothalamic injections of glutamate, kainic acid, D,L-alpha-amino-3-hydroxy-5-methyl-isoxazole propionic acid or N-methyl-D-aspartic acid rapidly elicit intense transient eating in rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Eating; Glutamates; Glutamic Acid; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
AMPA and NMDA binding sites in the hypothalamic lateral tuberal nucleus: implications for Huntington's disease.
Topics: Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Glutamates; Glutamic Acid; Humans; Huntington Disease; Hypothalamic Area, Lateral; Ibotenic Acid; Kainic Acid; Middle Aged; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 1993 |
Glutamate stimulates glucagon secretion via an excitatory amino acid receptor of the AMPA subtype in rat pancreas.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glucagon; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Islets of Langerhans; Kainic Acid; Male; Pancreas; Quinoxalines; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Amino Acid; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1993 |
Excitatory amino acid-induced slow biphasic responses of free intracellular calcium in human neuroblastoma cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium; Cycloleucine; Glutamates; Glutamic Acid; Humans; Ibotenic Acid; Kainic Acid; N-Methylaspartate; Receptors, Glutamate; Tumor Cells, Cultured | 1993 |
Aspartate and glutamate mediate excitatory synaptic transmission in area CA1 of the hippocampus.
Topics: 4-Aminopyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Calcium; Evoked Potentials; Glucose; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Pipecolic Acids; Pyramidal Tracts; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tritium | 1993 |
A pharmacological characterization of the mGluR1 alpha subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Diamino; Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cell Membrane; Clone Cells; Cricetinae; Cyanobacteria Toxins; Dizocilpine Maleate; Glutamates; Glutamic Acid; Ibotenic Acid; Inositol Phosphates; Kidney; Kinetics; Neurotoxins; Pertussis Toxin; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Recombinant Proteins; Transfection; Virulence Factors, Bordetella | 1993 |
Excitatory amino acid receptor mediation of sensory inputs to functionally identified dorsal horn neurons in cat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cats; Decerebrate State; Evoked Potentials; Glutamates; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ketamine; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synapses | 1993 |
Effects of bromohomoibotenate on metabotropic glutamate receptors.
Topics: Aminobutyrates; Animals; Binding, Competitive; Cell Line; Cerebral Cortex; Cricetinae; Cyclic AMP; Cycloleucine; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Kidney; Membranes; Phosphatidylinositols; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
Ibotenic acid lesion of nucleus basalis magnocellularis differentially affects cholinergic, glutamatergic and GABAergic markers in cortical rat brain regions.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Biomarkers; Cerebral Cortex; Flunitrazepam; Glutamic Acid; Hemicholinium 3; Ibotenic Acid; In Situ Hybridization; Male; Muscimol; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-A; Receptors, Kainic Acid; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Substantia Innominata | 1994 |
Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Cyclic AMP; Cycloleucine; DNA Primers; Female; Gene Library; Genetic Variation; Glutamic Acid; Ibotenic Acid; In Situ Hybridization; Kidney; Molecular Sequence Data; Neurotoxins; Oocytes; Polymerase Chain Reaction; Prosencephalon; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Restriction Mapping; RNA, Messenger; Spleen; Swine; Transfection; Xenopus | 1995 |
Time-related cortical amino acid changes after basal forebrain lesion: a microdialysis study.
Topics: Alzheimer Disease; Amino Acids; Animals; Brain Diseases; Cerebral Cortex; Chromatography, High Pressure Liquid; Fluorescence; Glutamic Acid; Glycine; Ibotenic Acid; Male; Microdialysis; Potassium; Rats; Rats, Sprague-Dawley; Serine; Taurine; Time Factors | 1995 |
Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Calcium; Chloride Channels; Cloning, Molecular; Conserved Sequence; Female; Gene Expression; Genetic Variation; Glutamates; Glutamic Acid; GTP-Binding Proteins; Humans; Ibotenic Acid; Molecular Sequence Data; Oocytes; Polymerase Chain Reaction; Rats; Receptors, Glutamate; Sequence Homology, Amino Acid; Type C Phospholipases; Virulence Factors, Bordetella; Xenopus | 1994 |
An ibotenate-selective metabotropic glutamate receptor mediates protein phosphorylation in cultured hippocampal pyramidal neurons.
Topics: Animals; Calcium; Cycloleucine; Diglycerides; Embryo, Mammalian; Glutamates; Glutamic Acid; Hippocampus; Ibotenic Acid; Inositol; Inositol Phosphates; Kainic Acid; Myristic Acid; Myristic Acids; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Pertussis Toxin; Phosphatidylcholines; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein Kinase C; Pyramidal Cells; Quisqualic Acid; Rats; Receptors, Glutamate; Stearic Acids; Virulence Factors, Bordetella | 1994 |
Metabotropic glutamate receptor activation induces astroglial swelling.
Topics: Animals; Animals, Newborn; Astrocytes; Calcium; Cell Size; Cells, Cultured; Cerebral Cortex; Cycloleucine; Glutamates; Glutamic Acid; Ibotenic Acid; Rats; Receptors, Metabotropic Glutamate | 1994 |
The effects of L-glutamate and trans-(+-)-1-amino-1,3-cyclopentanedicarboxylate on phosphoinositide hydrolysis can be pharmacologically differentiated.
Topics: Alanine; Animals; Animals, Newborn; Aspartic Acid; Benzoates; Brain; Cerebellum; Cycloleucine; Glutamic Acid; Glycine; Hippocampus; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kinetics; Neurotoxins; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
Glutamate stimulates the phosphorylation of glial fibrillary acidic protein in slices of immature rat hippocampus via a metabotropic receptor.
Topics: Animals; Autoradiography; Cycloleucine; Electrophoresis, Gel, Two-Dimensional; Excitatory Amino Acid Agonists; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Kinetics; Male; Neurotoxins; Phosphates; Phosphoproteins; Phosphorylation; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1994 |
Pharmacological characterization of metabotropic glutamate receptors in cultured cerebellar granule cells.
Topics: Alanine; Amino Acids, Diamino; Animals; Cells, Cultured; Cerebellum; Cyanobacteria Toxins; Cycloleucine; Drug Interactions; Enzyme Activation; Glutamates; Glutamic Acid; Ibotenic Acid; Magnesium; N-Methylaspartate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Quisqualic Acid; Rats; Receptors, Glutamate | 1993 |
Multiple subtypes of excitatory amino acid receptors coupled to the hydrolysis of phosphoinositides in rat brain.
Topics: Animals; Aspartic Acid; Brain; Cerebellum; Cerebral Cortex; Cycloleucine; Glutamates; Glutamic Acid; Hippocampus; Hydrolysis; Ibotenic Acid; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Receptors, Glutamate | 1993 |
The influence of prolonged antidepressant treatment on the changes in cyclic AMP accumulation induced by excitatory amino acids in rat cerebral cortical slices.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Colforsin; Cyclic AMP; Drug Interactions; Electroshock; Glutamic Acid; Ibotenic Acid; Imipramine; In Vitro Techniques; Male; Norepinephrine; Rats; Rats, Wistar; Time Factors | 1995 |
Ibotenic acid lesions of the dorsal prefrontal cortex disrupt the expression of behavioral sensitization to cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; Ibotenic Acid; Male; Microdialysis; Motor Activity; Narcotics; Neural Pathways; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Thalamus | 1998 |
The cerebral metabolic effects of manipulating glutamatergic systems within the basal forebrain in conscious rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Blood Glucose; Body Temperature; Brain Chemistry; Excitatory Amino Acid Agonists; Glucose; Glutamic Acid; Hemodynamics; Ibotenic Acid; Isoquinolines; Male; Prosencephalon; Rats; Stereotaxic Techniques | 1998 |
[Prenatal inhibition of intestinal vasoactive peptide and cerebral excitatory lesions in the newborn mouse].
Topics: Animals; Animals, Newborn; Cerebral Palsy; Disease Models, Animal; Drug Evaluation, Preclinical; Embryonic and Fetal Development; Excitatory Amino Acids; Female; Glutamic Acid; Humans; Ibotenic Acid; Infant, Newborn; Leukomalacia, Periventricular; Mice; Mice, Inbred Strains; Neuroprotective Agents; Pregnancy; Vasoactive Intestinal Peptide | 1999 |
Glutamate regulates IP3-type and CICR stores in the avian cochlear nucleus.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alanine; Animals; Benzoates; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Chick Embryo; Cochlear Nucleus; Cyclic AMP; Cycloleucine; Cysteine; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gallic Acid; Glutamic Acid; Glycine; Ibotenic Acid; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Receptors, Cytoplasmic and Nuclear; Ryanodine; Second Messenger Systems; Thionucleotides | 1999 |
Alterations of the dopaminergic and glutamatergic neurotransmission in adult rats with postnatal ibotenic acid hippocampal lesion.
Topics: Age Factors; Animals; Apomorphine; Cerebral Cortex; Dopamine Agonists; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Ibotenic Acid; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Membranes; Synaptic Transmission | 1999 |
Effects of lesions to the glutamatergic afferents to the nucleus accumbens in the modulation of reactivity to spatial and non-spatial novelty in mice.
Topics: Afferent Pathways; Amygdala; Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Hippocampus; Ibotenic Acid; Injections; Limbic System; Mice; Models, Neurological; Motor Activity; N-Methylaspartate; Nucleus Accumbens; Spatial Behavior; Valine | 1999 |
Co-existence in DUM neurones of two GluCl channels that differ in their picrotoxin sensitivity.
Topics: Animals; Bridged Bicyclo Compounds; Chloride Channels; Cockroaches; Electric Conductivity; GABA Antagonists; Ganglia, Invertebrate; Glutamic Acid; Ibotenic Acid; Insecticides; Male; Neurons; Nitriles; Patch-Clamp Techniques; Picrotoxin; Pyrazoles | 2000 |
N-methyl-D-aspartate but not glutamate induces the release of hydroxyl radicals in the neonatal rat: modulation by group I metabotropic glutamate receptors.
Topics: Animals; Animals, Newborn; Corpus Striatum; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hydroxybenzoates; Hydroxyl Radical; Hypoxia-Ischemia, Brain; Ibotenic Acid; Indans; Microdialysis; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols | 2000 |
Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization.
Topics: Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Hydrogen Bonding; Ibotenic Acid; Ion Channel Gating; Ligands; Microinjections; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Receptors, AMPA; Recombinant Fusion Proteins; Structure-Activity Relationship; Water; Xenopus laevis | 2001 |
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4.
Topics: Animals; Basal Ganglia; Cell Death; Cell Survival; Cells, Cultured; Choline O-Acetyltransferase; Cyclic AMP; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exenatide; Glial Fibrillary Acidic Protein; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glutamic Acid; Hippocampus; Ibotenic Acid; Immunohistochemistry; Nerve Degeneration; Neurons; Parasympathetic Nervous System; Peptide Fragments; Peptides; Protein Precursors; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptors, Glucagon; Venoms | 2002 |
Subthalamic GAD gene therapy in a Parkinson's disease rat model.
Topics: Animals; Dependovirus; Disease Models, Animal; Dopamine; Electric Stimulation; Electrophysiology; gamma-Aminobutyric Acid; Genetic Therapy; Genetic Vectors; Glutamate Decarboxylase; Glutamic Acid; Humans; Ibotenic Acid; Isoenzymes; Male; Mesencephalon; Mice; Motor Activity; Nerve Degeneration; Neurons; Oxidopamine; Parkinsonian Disorders; Phenotype; Rats; Stem Cells; Substantia Nigra; Subthalamic Nucleus; Synaptic Transmission; Transgenes | 2002 |
Pharmacological properties of l-glutamate receptors associated with the crayfish hindgut.
Topics: Animals; Arthropods; Astacoidea; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Heterocyclic Compounds; Ibotenic Acid; Intestines; Kainic Acid; Muscle, Skeletal; Muscle, Smooth; Neurotoxins; Polyamines; Potassium; Quisqualic Acid; Receptors, Glutamate | 2003 |
Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound.
Topics: Amino Acid Chloromethyl Ketones; Amyloid beta-Peptides; Animals; Cell Death; Cysteine; Dioxolanes; Drug Interactions; Excitatory Amino Acid Agonists; Garlic; Glutamic Acid; Hippocampus; Ibotenic Acid; Neurons; Neuroprotective Agents; Organ Culture Techniques; Purines; Rats; Rats, Wistar | 2003 |
Hypothalamic regulation of pancreatic secretion is mediated by central cholinergic pathways in the rat.
Topics: Animals; Antibodies, Monoclonal; Autonomic Pathways; Central Nervous System; Cholinergic Agents; Decerebrate State; Duodenum; Electrophysiology; Excitatory Amino Acid Agonists; Functional Laterality; Glutamic Acid; Hemicholinium 3; Hypothalamus; Ibotenic Acid; Immunotoxins; Injections, Intraventricular; Male; Muscarinic Agonists; N-Glycosyl Hydrolases; Neurons, Efferent; Pancreas; Parasympathetic Nervous System; Prosencephalon; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Ribosome Inactivating Proteins, Type 1; Saporins; Scopolamine; Septal Nuclei; Vagus Nerve | 2003 |
Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor.
Topics: Amino Acid Transport Systems, Neutral; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Hippocampus; Ibotenic Acid; Inhibition, Psychological; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle | 2003 |
Role of the medial prefrontal cortex in N-methyl-D-aspartate receptor antagonist induced sensorimotor gating deficit in rats.
Topics: Animals; Apomorphine; Denervation; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Ibotenic Acid; Male; Neural Inhibition; Neural Pathways; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Schizophrenia; Synaptic Transmission | 2004 |
Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid.
Topics: Aminobutyrates; Animals; Calcium Chloride; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Agonists; Glutamic Acid; Glycine; Ibotenic Acid; In Vitro Techniques; Male; Neurons; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes | 2004 |
Mutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues.
Topics: Cell Differentiation; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Ibotenic Acid; Immunohistochemistry; Kinetics; Ligands; Lysine; Models, Chemical; Models, Genetic; Models, Molecular; Mutation; Point Mutation; Protein Binding; Protein Conformation; Quisqualic Acid; Receptors, Metabotropic Glutamate; Serine; Transfection | 2004 |
The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid.
Topics: 2-Amino-5-phosphonovalerate; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Kainic Acid; Ligands; Membrane Potentials; Models, Molecular; N-Methylaspartate; Pyrazoles; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thermodynamics; Tritium | 2004 |
Glutamatergic chloride currents associated to glutamate transport?
Topics: Amino Acid Transport System X-AG; Animals; Chloride Channel Agonists; Chloride Channels; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Glutamic Acid; Ibotenic Acid; In Vitro Techniques | 2005 |
Topiramate prevents excitotoxic damage in the newborn rodent brain.
Topics: Alanine; Animals; Animals, Newborn; Brain; Cerebral Palsy; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fructose; Glutamic Acid; Humans; Hypoxia, Brain; Ibotenic Acid; Infant, Newborn; Leukomalacia, Periventricular; Male; Mice; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Topiramate; Treatment Outcome | 2005 |
Erythropoietin is neuroprotective against NMDA-receptor-mediated excitotoxic brain injury in newborn mice.
Topics: Animals; Animals, Newborn; Brain; Cytoprotection; Disease Models, Animal; Drug Administration Schedule; Erythropoietin; Female; Glutamic Acid; Humans; Ibotenic Acid; Infant, Newborn; Injections, Intraventricular; Leukomalacia, Periventricular; Male; Mice; Nerve Degeneration; Neuroprotective Agents; Neurotoxins; Receptors, Erythropoietin; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Time Factors | 2006 |
Role of substantia innominata in cerebral blood flow autoregulation.
Topics: Analysis of Variance; Animals; Blood Circulation Time; Blood Pressure; Cerebrovascular Circulation; Excitatory Amino Acid Agonists; Functional Laterality; Glutamic Acid; Homeostasis; Ibotenic Acid; In Vitro Techniques; Laser-Doppler Flowmetry; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Substantia Innominata | 2007 |
Glial alterations in the hippocampus of rats submitted to ibotenic-induced lesion of the nucleus basalis magnocellularis.
Topics: Animals; Astrocytes; Avoidance Learning; Basal Nucleus of Meynert; Brain Damage, Chronic; Cell Count; Cholinergic Fibers; Dementia; Disease Models, Animal; Exploratory Behavior; Follow-Up Studies; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Habituation, Psychophysiologic; Hippocampus; Ibotenic Acid; Immunohistochemistry; Male; Nerve Growth Factors; Rats; Rats, Wistar; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Statistics, Nonparametric; Time Factors | 2008 |
Neonatal ventral hippocampal lesions in male and female rats: effects on water maze, locomotor activity, plus-maze and prefrontal cortical GABA and glutamate release in adulthood.
Topics: Analysis of Variance; Animals; Animals, Newborn; Exploratory Behavior; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Maze Learning; Memory; Motor Activity; Potassium; Prefrontal Cortex; Random Allocation; Rats; Sex Characteristics; Swimming | 2009 |
Glutamatergic neurotransmission in the procerebrum (olfactory center) of a terrestrial mollusk.
Topics: Action Potentials; Amino Acid Sequence; Animal Structures; Animals; Biological Clocks; Gastropoda; Glutamic Acid; Ibotenic Acid; Molecular Sequence Data; Olfactory Pathways; Phylogeny; Quinoxalines; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Smell; Species Specificity; Synaptic Transmission; Vesicular Glutamate Transport Proteins | 2009 |
Descending glutamatergic pathways of PFC are involved in acute and chronic action of methylphenidate.
Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Stimulants; Dopamine; Drug Administration Schedule; Glutamic Acid; Ibotenic Acid; Male; Methylphenidate; Motor Activity; Neural Pathways; Neurons; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Ventral Tegmental Area | 2009 |
Interhemispheric regulation of the medial prefrontal cortical glutamate stress response in rats.
Topics: Adrenergic alpha-Antagonists; Amino Acids; Analysis of Variance; Animals; Baclofen; Benzazepines; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine Antagonists; Excitatory Amino Acid Agonists; Functional Laterality; GABA Agonists; Glutamic Acid; Ibotenic Acid; Male; Microdialysis; Neural Pathways; Oxathiins; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Stress, Psychological; Tail; Tetrodotoxin | 2010 |
The glutamatergic component of the mesocortical pathway emanating from different subregions of the ventral midbrain.
Topics: Adrenergic Agents; Animals; Biotin; Dextrans; Excitatory Amino Acid Agonists; Glutamate Decarboxylase; Glutamic Acid; Ibotenic Acid; Male; Nerve Fibers; Neural Pathways; Neurons; Oxidopamine; Phytohemagglutinins; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase; Ventral Tegmental Area; Vesicular Glutamate Transport Protein 2 | 2012 |
Effect of bFGF on neuronal damage induced by sequential treatment of amyloid β and excitatory amino acid in vitro and in vivo.
Topics: Amyloid beta-Peptides; Animals; Cerebral Cortex; Dizocilpine Maleate; Fibroblast Growth Factor 2; Glutamic Acid; Hippocampus; Ibotenic Acid; Learning; Male; Neurons; Neuroprotective Agents; Peptide Fragments; Rats; Time Factors | 2012 |
Impaired adrenergic-mediated plasticity of prefrontal cortical glutamate synapses in rats with developmental disruption of the ventral hippocampus.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Conditioning, Psychological; Developmental Disabilities; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Extinction, Psychological; Female; Glutamic Acid; Hippocampus; Ibotenic Acid; In Vitro Techniques; Male; Mitogen-Activated Protein Kinase 3; Neuronal Plasticity; Oxathiins; Prefrontal Cortex; Pregnancy; Rats; Receptors, Adrenergic, alpha-1; Synapses | 2014 |
The sigma-1 receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) protects against newborn excitotoxic brain injury by stabilizing the mitochondrial membrane potential in vitro and inhibiting microglial activation in vivo.
Topics: Animals; Animals, Newborn; Apoptosis; Apoptosis Inducing Factor; Brain Injuries; Caspase 3; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamic Acid; Glycoproteins; Haloperidol; Hippocampus; Ibotenic Acid; Membrane Potential, Mitochondrial; Mice; Microglia; Neurons; Receptors, sigma; Sigma-1 Receptor; Statistics, Nonparametric | 2014 |
Magnesium Sulfate Prevents Neurochemical and Long-Term Behavioral Consequences of Neonatal Excitotoxic Lesions: Comparison Between Male and Female Mice.
Topics: Aging; Animals; Animals, Newborn; Brain; Calcium Channel Blockers; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Functional Laterality; Gait Disorders, Neurologic; gamma-Aminobutyric Acid; Glutamic Acid; Ibotenic Acid; Longitudinal Studies; Magnesium Sulfate; Male; Mice; Motor Skills; Neurotoxicity Syndromes; Sex Factors; Vesicular Glutamate Transport Protein 1 | 2017 |
Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells.
Topics: AMP-Activated Protein Kinases; Autophagosomes; Autophagy; Autophagy-Related Protein-1 Homolog; Beclin-1; Cell Line, Tumor; Energy Metabolism; Forkhead Box Protein O3; Glutamic Acid; Humans; Ibotenic Acid; Intracellular Signaling Peptides and Proteins; Mechanistic Target of Rapamycin Complex 1; Memantine; Microtubule-Associated Proteins; Necrosis; Neuroblastoma; Nutrients; Receptors, N-Methyl-D-Aspartate; Sequestosome-1 Protein; Transcription, Genetic | 2020 |
Ibotenic Acid Biosynthesis in the Fly Agaric Is Initiated by Glutamate Hydroxylation.
Topics: Amanita; Glutamic Acid; Hydroxylation; Ibotenic Acid; Muscimol | 2020 |
Ablation of olfactory bulb glutamatergic neurons induces depressive-like behaviors and sleep disturbances in mice.
Topics: Ablation Techniques; Animals; Depression; Excitatory Amino Acid Agonists; Glutamic Acid; Ibotenic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Olfactory Bulb; Random Allocation; Sleep; Sleep Wake Disorders | 2020 |