glutamic acid has been researched along with histidine in 438 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (8.45) | 18.7374 |
| 1990's | 113 (25.80) | 18.2507 |
| 2000's | 195 (44.52) | 29.6817 |
| 2010's | 75 (17.12) | 24.3611 |
| 2020's | 18 (4.11) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Anthony, A; Augustyn, E; Bauer, J; Campbell, J; Chien, HC; Colas, C; Finke, K; Flint, A; Fotiadis, D; Giacomini, KM; Hall, C; Hansen, L; Heeren, N; Hernandez, C; Schlessinger, A; Springer, S; Stoner, L; Thomas, AA; Venteicher, B; Zur, AA | 1 |
| LaRoe, DJ; Vik, SB | 1 |
| Kim, H; Patel, MS | 1 |
| Engstrand, C; Forsman, C; Liang, Z; Lindskog, S | 1 |
| Burke, GT; Chu, YC; Katsoyannis, PG; Zong, L | 1 |
| Inouhe, M; Ishikawa, Y; Joho, M; Kunikane, M; Murayama, T; Tohoyama, H | 1 |
| Béguin, P; Navas, J | 1 |
| Drescher, DG; Drescher, MJ | 1 |
| Dauter, Z; Dodson, EJ; Dodson, GG; Dunn, MF; Hill, CP | 1 |
| Caprio, J; Wegert, S | 1 |
| Barras, F; Bortoli-German, I; Chippaux, M; Haiech, J; Py, B | 1 |
| Anderson, JW; Bhanot, P; Georges, F; Klevit, RE; Waygood, EB | 1 |
| Benen, J; de Kok, A; van Berkel, W; Veeger, C; Visser, T; Zak, Z | 1 |
| Anderson, RJ; Breckon, R; Dillingham, MA; Dixon, BS; Kaehny, MM | 1 |
| Horikoshi, N; Natori, S; Sekimizu, K | 1 |
| Hamano, S; Morita, K; Oka, M; Teraoka, K | 1 |
| McNutt, M; Mullins, LS; Pace, CN; Raushel, FM | 1 |
| Hallenga, K; Stanssens, P; Steyaert, J; Wyns, L | 1 |
| Bauman, MJ; Mawhinney, TD; Peterson, E; Rarey, KE; Raymer, SL; Schweitzer, VG; Woodson, BT | 1 |
| Schwartz, EA | 1 |
| Acher, R; Chauvet, J; Chauvet, MT; Michel, G; Rouillé, Y | 1 |
| Bakken, V; Högh, BT; Jensen, HB | 1 |
| Kaback, HR; Lee, JA; Püttner, IB | 1 |
| Auld, DS; Vallee, BL | 1 |
| Dean, RT; McElligott, MA; Wolff, SP | 1 |
| Byun, SM; Kim, JH; Lee, BR; Park, SK | 1 |
| Carvounis, CP; Carvounis, G; Wilk, BJ | 1 |
| Cohen, AS; Connors, LH; Gertz, MA; Kyle, RA; Skinner, M | 1 |
| Gerok, W; Häussinger, D; Meijer, AJ; Sies, H; Soboll, S; Tager, JM | 1 |
| Antes, LM; Carrasco, N; Kaback, HR; Poonian, MS | 1 |
| Arrieta, A; Bonilla, E; Prasad, AL | 1 |
| Cain, BD; Simoni, RD | 1 |
| Cupples, CG; Miller, JH | 1 |
| Hynes, MJ; Polkinghorne, MA | 1 |
| Van Etten, RL | 1 |
| Fujita, S; Kobayashi, Y; Ohta, Y; Saito, S | 1 |
| Miller, AM; Schwartz, EA | 1 |
| Engerman, RL; Kern, TS | 1 |
| He, MM; Hubbell, WL; Kaback, HR; Voss, J | 1 |
| Gaunt, MT; Huber, RE; Martinez-Bilbao, M | 1 |
| Choudhury, K; Marzocchi, MP; Neri, F; Poulos, TL; Smulevich, G; Willemsen, O | 1 |
| Aasa, R; Adelroth, P; Brzezinski, P; Gennis, RB; Malmström, BG; Mitchell, DM | 1 |
| Cai, Y; Ewan, RC; Zimmerman, DR | 1 |
| Aranibar, N; Kang, D; Karbach, D; Müller-Berger, S; Passow, H; Rüterjans, H; Wood, PG | 1 |
| Chu, HA; Debus, RJ; Nguyen, AP | 2 |
| Iida, K; Moss, J; Takada, T | 1 |
| Baykov, AA; Cooperman, BS; Goldman, A; Lahti, R; Magretova, NN; Velichko, IS; Velichko, IV; Volk, SE | 1 |
| Haser, R; Kadziola, A; Svensson, B; Søgaard, M | 1 |
| Bertalan, C; Farkas, E; Kowalik-Jankowska, T; Kozlowski, H; Lebkiri, A; Sóvágó, I | 1 |
| Gibbs, MR; Leslie, AG; Lewendon, A; Murray, IA; Shaw, WV | 1 |
| Warwicker, J | 1 |
| Joshi, AA; McDonald, MJ | 1 |
| Frimpong, K; Rodwell, VW | 1 |
| Jakobs, C; Majewski, C; Trebst, A; Uhrig, J | 1 |
| Trzewikowska, M; Walczewska, B | 1 |
| Gohda, K; Hakoshima, T; Oka, K; Tomita, K | 1 |
| Kanner, BI; Pines, G; Zhang, Y | 1 |
| Ahlman, B; Andersson, K; Hedenborg, L; Leijonmarck, CE; Ljungqvist, O; Wernerman, J | 1 |
| Cohen, A; Jones, LA; Kane, K; Milunsky, A; Myles, N; Skare, J; Skinner, M | 1 |
| Doseeva, VV; Galkin, AG; Gazaryan, IG; Tishkov, VI | 1 |
| Borzykh, OA; Chernokalskaya, EB; Hartley, RW; Kipenskaya, LV; Leschinskaya, IB; Moiseyev, GP; Struminskaya, NK; Yakovlev, GI; Znamenskaya, LV | 1 |
| Antonio, BJ; Vik, SB | 1 |
| Roux, B; Walsh, CT | 1 |
| Boileau, G; Crine, P; Le Moual, H; Roques, BP | 1 |
| Campbell, AK; Watkins, NJ | 1 |
| Bosch, D; Struyvé, M; Tommassen, J; Visser, J | 1 |
| Berelowitz, M; Bruno, JF; Song, J; Xu, Y | 1 |
| Moiseyev, GP; Yakovlev, GI | 1 |
| Harata, K; Jigami, Y; Muraki, M | 1 |
| Birktoft, JJ; Breddam, K; Nienaber, VL | 1 |
| Doseeva, VV; Galkin, AG; Gazarian, IG; Tishkov, VI | 1 |
| Cantoni, O; Cattabeni, F; Guidarelli, A; Palomba, L | 1 |
| Rao, VS; Seshadri, K; Vishveshwara, S | 1 |
| Eidels, L; Hooper, KP | 1 |
| Lee, JI; Varela, MF; Wilson, TH | 1 |
| Nakano, R; Sato, H; Shimizu, T | 1 |
| Liu, Y; Samuel, CE | 1 |
| Maley, F; Reddy, A | 1 |
| Hampl, H; Nündel, M; Riedel, E; Steudle, V | 1 |
| Brew, K; Grobler, JA; Malinovskii, VA; Tian, J | 1 |
| Briggs, C; Mincone, L; Phelps, A; Wohlrab, H | 1 |
| Eritja, R; Schliebs, W; Thanki, N; Wierenga, R | 1 |
| Dekker, EE; Johnson, AR | 1 |
| Czaplinski, K; Peltz, SW; Weng, Y | 1 |
| Birch, NP; Brennan, SO; George, PM; Ledgerwood, EC | 1 |
| Ishimori, K; Morishima, I; Tanaka, M | 1 |
| Curtius, HC; Ficner, R; Ghisla, S; Hölzer, M; Köster, S; Stier, G; Suck, D | 1 |
| Deng, H; He, XY; Yang, SY | 1 |
| Alam, M; Brooun, A; Zhang, W | 1 |
| Janáky, R; Jenei, Z; Oja, SS; Saransaari, P; Varga, V | 1 |
| Ishimori, K; Kitagawa, T; Morishima, I; Mukai, M; Tanaka, M | 1 |
| Jacobson, GR; Saraceni-Richards, CA | 1 |
| Forman-Kay, JD; Singer, AU | 1 |
| Dyer, RB; Hummer, G; Puustinen, A; Riistama, S; Wikström, M; Woodruff, WH | 1 |
| Bailey, JA; Dyer, RB; Mecklenburg, SL; Puustinen, A; Wikström, M; Woodruff, WH | 1 |
| Hori, H; Mogi, T; Tsubaki, M | 1 |
| Petersen, BO; Shuman, S; Wittschieben, J | 1 |
| Heath, RJ; Rock, CO | 1 |
| Bakillah, A; Hussain, MM; Jamil, H | 1 |
| Botting, HG; Darling, P; Davis, TA; Pencharz, PB; Sarwar, G | 1 |
| Cone, RD; Lu, D; Vage, DI | 1 |
| Beck, M; Sakmar, TP; Siebert, F | 1 |
| Hoover, DM; Jarrett, JT; Ludwig, ML; Matthews, RG | 1 |
| Meneghini, C; Morante, S | 1 |
| Barrett, AJ; Chen, JM; Rawlings, ND; Stevens, RA; Wray, PW | 1 |
| Brooke, JS; Cha, JH; Eidels, L | 1 |
| Coughtrie, MW; Dajani, R; Hood, AM | 1 |
| Bonn, G; Fiechtner, B; Glossmann, H; Huck, CW; Moebius, FF; Soellner, KE | 1 |
| Bizouarn, T; Fjellström, O; Hu, X; Rydström, J; Zhang, J | 1 |
| Suzuki, K; Tanaka, T; Yamada, T | 1 |
| Josse, D; Lockridge, O; Masson, P; Renault, F; Rochu, D; Schopfer, LM; Xie, W | 1 |
| Blanchard, CZ; Frantom, PA; Lee, YM; Waldrop, GL | 1 |
| Sun, S; Toney, MD | 1 |
| Kass, IJ; Sampson, NS; Vrielink, A; Yue, QK | 1 |
| Daubner, SC; Fitzpatrick, PF | 1 |
| Armitage, IM; Karschnia, EJ; Kirby, TL; Lange, AJ; Live, DH; Okar, DA; von Weymarn, LB | 1 |
| Hedrich, R; Hoth, S | 1 |
| Hashimoto, K; Kikuchi, A; Shirouzu, M; Yokoyama, S | 1 |
| Jung, CM; Katayama, S; Matsushita, O; Minami, J; Okabe, A; Sakurai, J | 1 |
| Elsliger, MA; Hanson, GT; Kallio, K; Remington, SJ; Wachter, RM | 1 |
| Cummins, PM; Glucksman, MJ; Margulies, EH; Pabon, A | 1 |
| Drabløs, F; Nicholson, DG; Rønning, M | 1 |
| Gama, Y; Hasegawa, T; Hayashi, K; Kaneko, S; Kuno, A; Kusakabe, I; Shimizu, D; Taira, K | 1 |
| Hubbell, WL; Kaback, HR; Zen, KC; Zhao, M | 1 |
| Fukasawa, K; Fukasawa, KM; Harada, M; Hirose, J; Iwamoto, H | 1 |
| Lu, Y; Wang, X | 1 |
| Arninkhof, MJ; Kersten, MA; Op den Camp, HJ; van der Drift, C; Van Griensven, LJ | 1 |
| Mine, Y; Zhang, JW | 1 |
| Ackerson, L; Edgerton, VR; Maidment, NT; Ta-Haung, J; Walwyn, WM | 1 |
| Bravo, J; Bujons, J; Ens, W; Fita, I; Hu, B; Loewen, PC; Maté, MJ; Sevinc, MS; Switala, J | 1 |
| Bruix, M; Gavilanes, JG; Lacadena, J; Mancheño, JM; Martínez del Pozo, A; Martínez-Ruiz, A; Oñaderra, M; Pérez-Cañadillas, JM | 1 |
| Ibarra-Molero, B; Loladze, VV; Makhatadze, GI; Sanchez-Ruiz, JM | 1 |
| Lee, JP; Zhang, S | 1 |
| Baker, EN; Bewley, MC; He, QY; MacGillivray, RT; Mason, AB; Smith, CA; Woodworth, RC | 1 |
| Busch, JL; Davy, SL; Hannan, JP; James, R; Moore, GR; Thomson, AJ | 1 |
| Dove, JE; Klinman, JP; Schwartz, B; Williams, NK | 1 |
| Abduragimov, AR; Gasymov, OK; Glasgow, BJ; Yusifov, TN | 1 |
| Imoto, T; Ishibashi, R; Masumoto, K; So, T; Ueda, T | 1 |
| Eswar, N; Ramakrishnan, C | 1 |
| Wikström, M | 1 |
| Monsan, P; Potocki de Montalk, G; Remaud-Simeon, M; Sarçabal, P; Svensson, B; Willemot, R | 1 |
| Atwood, CS; Bush, AI; Huang, X; Khatri, A; Kim, YS; Moir, RD; Roher, AE; Scarpa, RC; Tanzi, RE | 1 |
| Ginsburg, A; Nosworthy, NJ; Peterkofsky, A; Ruvinov, SB; Sondej, M; Szczepanowski, RH; Umland, TC | 1 |
| Ferry, JG; Tripp, BC | 1 |
| Gao, ZG; Ijzerman, AP; Jacobson, KA; Jiang, Q | 1 |
| Devany, MH; Lange, AJ; Live, DH; Okar, DA | 1 |
| Barja, F; Curty, LK; Köhler, T; Pechère, JC; van Delden, C | 1 |
| Håkansson, K; Miller, CG; Wang, AH | 1 |
| Adams, MJ; Cosgrove, MS; Gover, S; Levy, HR; Naylor, CE; Vandeputte-Rutten, L | 1 |
| Bräuner-Osborne, H; Jensen, AA; Jensen, LB; O'Hara, PJ; Sheppard, PO | 1 |
| Fierke, CA; Jackman, JE; Raetz, CR | 1 |
| Barquera, B; Gennis, RB; Hellwig, P | 1 |
| Parkin, G | 1 |
| Grogan, J; McKnight, CJ; Oppenheim, FG; Troxler, RF | 1 |
| Agrawal, A; Greenhough, TJ; Shrive, AK; Volanakis, JE | 1 |
| Amblar, M; Corrales, MA; de Lacoba, MG; Lopez, P | 1 |
| Christensen, T; DiTusa, CA; Fierke, CA; Mahapatro, M; McCall, KA; Toone, EJ | 1 |
| Calabrese, JC; Jordan, DB; Liao, DI; Viitanen, PV; Wawrzak, Z | 1 |
| Gether, U; Loland, CJ; Norregaard, L | 1 |
| Miranda, R; Orrego, F; Saldate, C | 1 |
| Glavas, S; Tanner, ME | 1 |
| Batra, R; Khayat, R; Lagacé, L; Massariol, MJ; Tong, L | 1 |
| Duboc, P; Hajjaj, H; Niederberger, P | 1 |
| Furey, W; Guo, F; Hübner, G; Jordan, F; Liu, M; Sergienko, EA; Tittmann, K; Wang, J | 1 |
| Banaszak, LJ; Barycki, JJ; O'Brien, LK; Strauss, AW | 1 |
| Bagga, S; Batra, JK; Gaur, D; Nair, DT; Nayak, SK; Salunke, DM | 1 |
| Cook, RJ | 1 |
| Bangera, MG; McGuire, KA; Olsen, JG; Siggaard-Andersen, M; von Wettstein-Knowles, P | 1 |
| Abdulrazzaq, YM; Ibrahim, A | 1 |
| Brokx, SJ; Delbaere, LT; Kindrachuk, J; Napper, S; Pally, E; Waygood, EB | 1 |
| Murphy, OJ; Thompson, LK; Weis, RM; Yi, X | 1 |
| Dijkhuizen, L; Dijkstra, BW; Kralj, S; Leemhuis, H; Uitdehaag, JC; van der Veen, BA | 1 |
| Bijnens, AP; Brouwers, E; Declerck, PJ; Gils, A; Knockaert, I; Komissarov, AA; Shore, JD; Stassen, JM | 1 |
| Ida, K; Matsuura, T; Norioka, S; Sakai, H; Sakiyama, F; Sato, M; Unno, M | 1 |
| Baumann, U; Hege, T | 1 |
| Ramos, JL; Ruiz, R | 1 |
| Fraser, ME; Joyce, MA; Ryan, DG; Wolodko, WT | 1 |
| Patzke, H; Tsai, LH | 1 |
| Dahms, NM; Kim, JJ; Olson, LJ; Zhang, J | 1 |
| Hasnain, S; Krupa, JC; Ménard, R; Mort, JS; Nägler, DK | 1 |
| Palecz, B | 1 |
| Alam, M; Lehner, R; Vance, DE | 1 |
| Anderson, RG; Liu, P; Sampson, NS; Yin, Y | 1 |
| Esaki, N; Nakayama, T; Nishino, T; Yoshimune, K; Yoshimura, T | 1 |
| Hoshi, T; Lee, HC; Lu, T; Padanilam, BA; Padanilam, BJ; Shibata, EF | 1 |
| Legler, PM; Massiah, MA; Mildvan, AS | 1 |
| Bohác, M; Damborský, J; Koca, J; Monincová, M; Nagata, Y; Prokop, M; Prokop, Z; Tsuda, M | 1 |
| Lodeiro, S; Matsuda, SP; Meyer, MM; Patel, AJ; Segura, MJ | 1 |
| Allen, JP; Kálmán, L; LoBrutto, R; Narváez, AJ; Williams, JC | 1 |
| Ferry, JG; Rowlett, RS; Silverman, DN; Tripp, BC; Tu, C | 1 |
| Bender, RA; Janes, BK; Rosario, CJ | 1 |
| Carrick, KL; Topal, MD | 1 |
| Adachi, S; Ichihara, K; Lee, DS; Matsunaga, I; Ogura, H; Park, SY; Shiro, Y; Sugimoto, H; Yamada, A | 1 |
| Kursula, I; Wierenga, RK | 1 |
| Dang, BN; Fitch, CA; García-Moreno E, B; Schwehm, JM; Stites, WE | 1 |
| Conesa, A; Hager, LP; Punt, PJ; Yi, X | 1 |
| Gancedo, C; Latchev, K; Ozimek, P; van der Klei, IJ; van Dijk, R; Veenhuis, M; Wang, DY | 1 |
| Daubner, SC; Ellis, HR; Fitzpatrick, PF; Ralph, EC; Willmon, OJ | 1 |
| Laskowski, M; Markley, JL; Qasim, MA; Song, J | 1 |
| Cui, Q; Elstner, M; Frauenheim, T; Karplus, M; Kaxiras, E; Munih, P | 1 |
| Barboric, M; Blackwell, TK; Peterlin, BM; Zhang, F | 1 |
| Balcar, VJ; Bröer, A; Bröer, S; Bubb, WA; Conigrave, AD; Hare, N; McEwan, SR; McQuillan, JA; Rae, C | 1 |
| Arabshahi, A; Beebe, JA; Clifton, JG; Frey, PA; Petsko, GA; Ringe, D | 1 |
| Djordjevic, S; Koshkin, A; Nunn, CM; Ortiz de Montellano, PR | 1 |
| Kantrowitz, ER; Wojciechowski, CL | 1 |
| Bosshard, HR; Marti, DN | 1 |
| Toustrup-Jensen, M; Vilsen, B | 1 |
| Alary, A; Cygler, M; Hecker, R; Lindner, HA; Lunin, VV; Ménard, R | 1 |
| Schwarz, H; Semialjac, M | 1 |
| ABRAMS, A; BORSOOK, H | 1 |
| Bonete, MJ; Díaz, S; Ferrer, J; Oren, A; Pérez-Pomares, F | 1 |
| FRY, BA; WICKREMASINGHE, RL | 1 |
| MEHLER, AH; TABOR, H | 1 |
| KNUDSON, AG | 1 |
| FRIEDBERG, F; HAYDEN, GA | 1 |
| BENNETT, MC; CHANARIN, I | 1 |
| QUINTO, G | 1 |
| FEREN, CJ; HEDRICK, LR | 1 |
| SHIBATA, K; TOHJO, M | 1 |
| CHISHOLM, M; SHARP, AA | 1 |
| ALLEN, DM; WHITEHEAD, RG | 1 |
| SAITO, T | 1 |
| Fisher, H; Leveille, GA | 1 |
| Bellamy, HD; Fox, RO; Kaluarachchi, WD; Liu, D; White, MA; Zhao, Y | 1 |
| Makarov, AA; Mitkevich, VA; Newsom, S; Pace, CN; Shaw, KL; Trevino, S; Yakovlev, GI | 1 |
| Bruix, M; García-Mayoral, MF; Gavilanes, JG; Ibarra-Molero, B; Lacadena, J; Martínez del Pozo, A; Pérez-Cañadillas, JM; Rico, M; Sanchez-Ruiz, JM; Santoro, J | 1 |
| Dodson, ML; Lloyd, RS; Meador, MG; Rajagopalan, L | 1 |
| Amon, LM; Archambault, J; Cameron, DR; Coulombe, R; Fink, D; Massariol, MJ; Thauvette, L; Titolo, S; Wang, Y; Welchner, E; White, PW; Yoakim, C | 1 |
| Iturrioz, X; Llorens-Cortes, C; Maigret, B; Okada, M; Rozenfeld, R | 1 |
| Dal Molin, F; Montecucco, C; Naletto, L; Romanello, V; Tonello, F | 1 |
| Gushansky, G; Sachs, G; Scott, DR; Weeks, DL | 1 |
| Draker, KA; Wright, GD | 1 |
| Arrabit, C; Finley, M; Fowler, C; Slesinger, PA; Suen, KF | 1 |
| Ambroggio, XI; Deshaies, RJ; Rees, DC | 1 |
| Fukada, K; Hirata, S; Nagano, S; Nakanishi, T; Okuno, T; Sakoda, S; Sato, T; Shimizu, A; Sugai, F; Yamamoto, Y; Zhou, Z | 1 |
| HAYAISHI, O; TABOR, H | 1 |
| Dahl, SW; Jensen, MR; Lauritzen, C; Led, JJ; Pedersen, J | 1 |
| Clay, C; Navratil, AM; Sanborn, BM; Zhong, M | 1 |
| Betz, M; Löhr, F; Rüterjans, H; Wienk, H | 1 |
| Jiang, W; Mao, X; Wang, W; Zhao, GP | 1 |
| Efremov, RG; Kosinsky, YA; Lutsenko, S; Morgan, CT; Tsivkovskii, R | 1 |
| Schmid, FX; Sterner, R | 1 |
| Jin, Y; Kitagawa, T; Nagai, M; Nagai, Y; Nagatomo, S | 1 |
| Karim, QN; Sidebotham, RL; Spencer, J; Worku, ML | 1 |
| Albert, A; Ariño, J; Barceló, A; Marquina, M; Muñoz, I; Ruiz, A | 1 |
| CLOWDUS, BF; CROOKSHANK, HR | 1 |
| Klingen, AR; Ullmann, GM | 1 |
| Andresen, BS; Bross, P; Corydon, TJ; Engel, PC; Frazier, DM; Gregersen, N; Hansen, J; Kenney, JM; McCandless, SE; O'Reilly, L; Olpin, SE; Winter, V | 1 |
| Chen, HY; Lima, S; Phillips, RS; Shim, D; Sundararaju, B; Tavakoli, K | 1 |
| Contreras-Shannon, V; Lin, AP; McAlister-Henn, L; McCammon, MT | 1 |
| Kamachi, T; Toraya, T; Yoshizawa, K | 1 |
| Ishikita, H; Knapp, EW | 1 |
| Albrecht, J; Hertz, L; Hilgier, W; Schousboe, A; Sonnewald, U; Waagepetersen, HS; Ziemińska, E | 1 |
| Guan, Z; McClerren, AL; Raetz, CR; Rudolph, J; Zhou, P | 1 |
| Asojo, OA; Borgstahl, GE; Lockridge, O; Masson, P; Nachon, F | 1 |
| Akana, J; Gerlt, JA; Rayment, I; Wise, EL; Yew, WS | 1 |
| Liman, ER; Liu, D; Zhang, Z | 1 |
| Grewer, C; Tao, Z | 1 |
| Okamoto, Y; Sugita, Y | 1 |
| Dalal, S; Starcevic, D; Sweasy, J | 1 |
| Arceci, M; Bozzoni, I; Caffarelli, E; Dlakic, M; Gioia, U; Laneve, P | 1 |
| Relyea, HA; Rimkus, S; van der Donk, WA; Wheatley, JL; Woodyer, R | 1 |
| Holland, IB; Jenewein, S; Jumpertz, T; Schmitt, L; Zaitseva, J | 1 |
| Bochtler, M; Bourenkov, G; Odintsov, SG; Rybin, V; Sabała, I | 1 |
| Li, ZF; Wang, HH; Wang, JD; Xie, J; Yang, YP; Zhang, M; Zhong, Y | 1 |
| Cunningham, FX; Gentleman, S; Miller-Ihli, NJ; Poliakov, E; Redmond, TM | 1 |
| Kandori, H; Mogi, T; Nakamura, H; Yamazaki, Y | 1 |
| Kannan, N; Neuwald, AF | 1 |
| Marti, DN | 1 |
| Lee, YM; Lim, C; Lin, YL | 1 |
| Batchelar, ET; McDonough, MA; Schofield, CJ; Sleeman, MC; Sorensen, JL | 1 |
| Chen, Z; Ding, MP; Fan, YY; Jin, CL; Li, Q; Luo, JH; Wu, XH; Yang, LX; Zhang, WP | 1 |
| Anan, I; Fahoum, S; Hellman, U; Holmgren, G; Jonasson, J; Lundgren, HE; Stafberg, C; Suhr, OB | 1 |
| Chen, Y; Ma, JX; Moiseyev, G; Takahashi, Y | 1 |
| Fu, A; Park, S; Rodermel, S | 1 |
| Ajamian, E; Cygler, M; Fraser, ME; Iannuzzi, P; Kernaghan, SD; Li, Y; Matte, A; Rangarajan, ES | 1 |
| Hildebrandt, ER; McCracken, J; Plummer, LJ; Porter, SB; Rogers, VA; Schmidt, WK | 1 |
| Chait, BT; Fushitani, K; Gorr, TA; Kao, WY; Knapp, JE; Qin, J; Riggs, AF; Riggs, CK; Smith, SS | 1 |
| Miller, AF; Rodgers, DW; Yikilmaz, E | 1 |
| Wang, S; Yu, H | 1 |
| Bernauer, J; Decottignies, P; Graille, M; Graziani, S; Liebl, U; Marchand, C; Myllykallio, H; Skouloubris, S; van Tilbeurgh, H; Zhou, CZ | 1 |
| Aliverti, A; Coda, A; de Rosa, M; Mattevi, A; Pandini, V; Pennati, A; Razeto, A; Vanoni, MA; Zanetti, G | 1 |
| McSweeney, S; Mitchell, EP; Romão, CV | 1 |
| Fernández, M; Zúñiga, M | 1 |
| Berrin, JG; Giardina, T; Herga, S; Perrier, J; Puigserver, A | 1 |
| Juge, N; Moriyama, Y; Omote, H; Yatsushiro, S; Yoshida, Y | 1 |
| Lapinski, PE; Perria, CL; Raghavan, M; Rajamanickam, V | 1 |
| Belitsky, BR; Picossi, S; Sonenshein, AL | 1 |
| Chen, Z; Dai, HB; Fan, YY; Fu, QL; Hu, WW; Luo, JH; Shen, Y; Wei, EQ | 1 |
| Chen, Z; Gong, YX; Lv, M; Shi, H; Wei, EQ; Zeng, QL; Zhu, YP; Zhu, YY | 1 |
| Al-Karadaghi, S; Hansson, M; Hansson, MD; Karlberg, T; Rahardja, MA | 1 |
| Drinker, M; Loll, PJ; Weeks, SD | 1 |
| Böcker, U; Haas, SL; Ruether, A; Schreiber, S; Singer, MV | 1 |
| Fernandes, PA; Ramos, MJ; Sousa, SF | 1 |
| Hunte, C; Klingen, AR; Palsdottir, H; Ullmann, GM | 1 |
| Badet, B; Badet-Denisot, MA; Boetzel, J; Floquet, N; Koteshwar, K; Richez, C; Stevens, J | 1 |
| Berni, R; Cendron, L; Folli, C; Percudani, R; Ramazzina, I; Zanotti, G | 1 |
| Chandra, H; Mishra, AK; Mishra, P; Shukla, G; Singh, S; Sinha, D; Tiwari, AK | 1 |
| Adayev, T; Bolton, DC; Chen-Hwang, MC; Hwang, YW; Lee, E; Murakami, N | 1 |
| Hattori, M; Kitao, T; Nakano, Y; Nogi, T; Takagi, J; Yasui, N | 1 |
| Borgstahl, GE; Bronshteyn, Y; Brunold, TC; Grove, LE; Miller, AF; Porta, J; Vahedi-Faridi, A; Yikilmaz, E | 1 |
| Ahmed, HU; Blakeley, MP; Cianci, M; Cruickshank, DW; Helliwell, JR; Hubbard, JA | 1 |
| Baptista, AM; Soares, CM; Teixeira, VH | 1 |
| Jones, AK; Sattelle, DB | 1 |
| Chen, X; Gründer, S; Paukert, M; Polleichtner, G; Schindelin, H | 1 |
| Cheng, HC; Gayler, KR; Gunawardana, D | 1 |
| Caflisch, A; Interlandi, G; Plückthun, A; Settanni, G; Wetzel, SK | 1 |
| Grabstein, K; Johnson, RS; Tirrell, DA; Wang, A; Winblade Nairn, N | 1 |
| Rainey, PB; Zhang, XX | 1 |
| Dyczynska, E; Sun, D; Syta, E; Zolkiewska, A | 1 |
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| Gauld, JW; Robinet, JJ | 1 |
| Myler, PJ; Olafson, RW; Rosenzweig, D; Smith, D; Zilberstein, D | 1 |
| Clarke, CE; Mathie, A; Vandenberg, JI; Veale, EL; Wyse, K | 1 |
| Nimigean, CM; Parsa, PV; Posson, DJ; Thompson, AN | 1 |
| Aftimos, S; Bicknell, LS; Maw, MA; Pitt, J; Ramadas, R; Robertson, SP | 1 |
| André, B; Boeckstaens, M; Marini, AM | 1 |
| Baldini, G; Bettati, S; Bosisio, C; Campanini, B; Chirico, G; Collini, M; D'Alfonso, L; Quercioli, V; Raboni, S | 1 |
| Fukada, S; Morita, T; Sugiyama, K | 1 |
| Abe, M; Abe, S; Erker, G; Hikage, T; Niemeyer, J; Takezawa, Y; Ueno, T; Watanabe, Y | 1 |
| Lan, J; Luo, K; Su, X; Xiang, Q; Xie, R | 1 |
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| Inoue, N; Kasahara, M; Miyaishi, A; Osawa, K; Osawa, Y; Shimada, E; Tabuchi, Y; Takahashi, J; Tanaka, K; Tsutou, A; Yamamoto, M; Yoshida, K | 1 |
| BODANSKY, O | 1 |
| Acton, TB; Aramini, JM; Chen, CX; Fischer, M; Honig, B; Maglaqui, M; Montelione, GT; Nair, R; Nwosu, C; Owens, LA; Rossi, P; Rost, B; Xiao, R | 1 |
| Bakar, FD; Berrisford, JM; Craven, CJ; Hounslow, AM; Huang, H; Mahadi, NM; Moir, AJ; Nathan, S; Nyon, MP; Rice, DW | 1 |
| Hu, F; Li, HX; Wei, ZG; Wu, JL; Zhao, HY | 1 |
| Frison, G; Ohanessian, G | 1 |
| Holyavka, MG; Kovaleva, TA; Kozhedub, SV; Rezvan, SG | 1 |
| Seeger, MA; van Veen, HW | 1 |
| Briones, R; Cid, LP; Niemeyer, MI; Sepúlveda, FV; Yusef, YR | 1 |
| Grimsley, GR; Pace, CN; Scholtz, JM | 1 |
| Dilović, I; Gliubich, F; Malpeli, G; Matković-Calogović, D; Zanotti, G | 1 |
| Allocati, N; Di Ilio, C; Federici, L; Gianni, S; Masulli, M | 1 |
| Anderson, JL; Dutton, PL; Koder, RL; Moser, CC; Reddy, KS; Solomon, LA | 1 |
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| Biagini, S; Blower, PJ; King, R; Mather, SJ; Surfraz, MB | 1 |
| Adolph, HW; Heinz, U; Hemmingsen, L; Kiefer, M | 1 |
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| Artursson, E; Ekström, F; Hörnberg, A; Pang, YP; Wärme, R | 1 |
| Bossa, F; Capitani, G; De Biase, D; Franssen, MC; John, RA; Lammens, TM; Pennacchietti, E | 1 |
| Diebold, AR; Egger, S; Nidetzky, B; Solomon, EI; Straganz, GD | 1 |
| Boscherini, F; Cotton, NP; Francia, F; Giachini, L; Jackson, JB; Venturoli, G; Veronesi, G; Whitehead, SJ | 1 |
| Babu, GN; Bala, L; Kalita, J; Khetrapal, CL; Kumar, A; Misra, UK; Singh, RL | 1 |
| Kaetzel, DM; McCorkle, JR; Novak, M; Yang, M; Zhang, Q | 1 |
| Chan, AW; Laskowski, RA; Selwood, DL | 1 |
| Chardwiriyapreecha, S; Iwaki, T; Kakinuma, Y; Mukaiyama, H; Sekito, T; Takegawa, K | 1 |
| Chen, J; Ghosh, K; Gibb, B; Gupta, K; Sharp, R; Van Duyne, GD | 1 |
| Kafka, AP; Kleffmann, T; McDowell, A; Rades, T | 1 |
| Quan, JM; Wu, XH; Wu, YD; Zou, GL | 1 |
| Fukasawa, KM; Hata, T; Hirose, J; Ono, Y | 1 |
| de Crécy-Lagard, V; Gregory, JF; Hanson, AD; Jeanguenin, L; Lara-Núñez, A; Mageroy, MH; Pribat, A; Rice, KC | 1 |
| Camoin, L; Kulyyassov, A; Lipinski, M; Moio, P; Ogryzko, V; Ramankulov, E; Vertut, D | 1 |
| Agar, JN; Brodkin, HR; D'Aquino, JA; Goldberg, IG; Karabacak, NM; Milne, AC; Novak, WR; Ondrechen, MJ; Payne, MS; Petsko, GA; Ringe, D | 1 |
| Przybylski, JL; Wetmore, SD | 1 |
| Altai, M; Graslund, T; Hofstrom, C; Orlova, A; Tolmachev, V; Wangsell, F | 1 |
| Baral, PK; James, MN; Kav, NN; Krishnaswamy, S | 1 |
| Alzate-Morales, JH; Caballero, J; Dreyer, I; González, W; González-Nilo, FD; Morales-Navarro, SE; Riedelsberger, J | 1 |
| Natarajan, J; Shanmugam, A | 1 |
| Vanderlinde, EM; Yost, CK | 1 |
| Ferla, MP; Gerth, ML; Rainey, PB | 1 |
| Blanc, PJ; François, JM; Goma, G; Hajjaj, H | 1 |
| Ashida, H; Gohda, J; Inoue, J; Kim, M; Kobayashi, T; Koyama, T; Mimuro, H; Mizushima, T; Nagai, S; Ogawa, M; Oyama, A; Sanada, T; Sasakawa, C; Shibata, Y; Suzuki, M | 1 |
| Badieyan, S; Bevan, DR; Zhang, C | 1 |
| Chumseng, S; Sinsuwan, S; Yamabhai, M; Yongsawatdigul, J | 1 |
| Arai, S; Blaber, M; Kurihara, K; Kuroki, R; Morimoto, S; Shoyama, Y; Takeuchi, A; Tamada, T; Taura, F | 1 |
| Ito, H; Kawaguchi, Y; Mine, T; Ogawa, M | 1 |
| Busch, S; Himmerlich, M; Hoffmann, C; Hüger, E; Krischok, S; Vinzenz, X; Wöllenstein, J | 1 |
| Dessingou, J; Pathak, RK; Rao, CP | 1 |
| Hou, CY; Kang, TJ; Kim, WH; Thu Ho, NA | 1 |
| Gao, Y; Mao, X; Marsh, M; Ran, T; Wang, M; Wang, W; Xu, D; Xu, L; Zhu, W | 1 |
| Amachawadi, RG; Elwakeel, EA; Nagaraja, TG; Nasser, ME; Nour, AM; Titgemeyer, EC | 1 |
| Ebrahimi, D; Hibbert, DB; Khoury, RR; Sutton, GJ | 2 |
| Andersen, EM; Khajo, A; Koder, RL; Magliozzo, RS; Zhang, L | 1 |
| Deng, YF; Kempson, IM; Liu, JR; Tseng, SJ; Yang, PC; Zeng, YF | 1 |
| Boček, P; Kubáň, P | 1 |
| Bal, W; Barnham, KJ; Drew, SC; Kenche, VB; Masters, CL; Zawisza, I | 1 |
| Deshpande, MV; Joshi, CV; Kapadnis, BP; Pathan, EK; Punekar, NS; Tupe, SG | 1 |
| Anastassov, I; Chappell, RL; Ripps, H; Shen, W | 1 |
| Chaffotte, AF; Dupret, JM; Haouz, A; Kubiak, X; Li de la Sierra-Gallay, I; Pluvinage, B; Rodrigues-Lima, F; Weber, P | 1 |
| He, Y; Sun, D; Sun, P; Tian, C; Xiao, L; Yu, M; Zhang, L | 1 |
| Bellia, F; Grasso, G; La Mendola, D; Magrì, A; Pietropaolo, A; Rizzarelli, E | 1 |
| Anastassov, I; Chappell, RL; Ripps, H | 1 |
| Bowman, L; Flanagan, L; Fyfe, PK; Hunter, WN; Parkin, A; Sargent, F | 1 |
| Pecoraro, VL; Zastrow, ML | 1 |
| Conti, PS; Fei, L; Shen, WC; Yap, LP; Zaro, JL | 1 |
| Coskuner, O; Wise, O | 1 |
| Bahl, M; Barnes, T; Bell, K; Califaretti, N; Campbell, C; DiSebastiano, KM; Dubin, JA; Hanning, R; Mourtzakis, M; Russell, C; Vance, V | 1 |
| Cha, HJ; Lee, JS; Park, KH; Park, SH; Tran, PL; Woo, EJ | 1 |
| Chen, Z; Dai, YJ; Feng, B; Hou, WW; Hu, WW; Ohtsu, H; Wu, DC; Xu, CL | 1 |
| Chekan, JR; Nair, SK; Peck, SC; Ulrich, EC; van der Donk, WA | 1 |
| Allegretti, M; Davies, KM; Klusch, N; Kühlbrandt, W; Mills, DJ; Vonck, J | 1 |
| Kakinuma, Y; Kawano-Kawada, M; Manabe, K; Murao, N; Sekito, T; Tone, J; Yoshimura, A | 1 |
| Bacares, R; Figueiredo, J; Melo, S; Ruggeri, J; Seruca, R; Shah, MA; Simões-Correia, J; Somar, J; Xiao, A; Zhang, L | 1 |
| Carlomagno, Y; DeTure, M; Dickson, DW; Hinkle, KM; Lin, WL; Pedraza, O; Rademakers, R; Ross, OA; Sanchez-Contreras, M; Tacik, P; Wszolek, ZK | 1 |
| Ansari, A; Jayapal, P; Rajaraman, G | 1 |
| Reeve, BW; Reid, SJ | 1 |
| Ghatak, S; Sikdar, SK | 1 |
| Alaayedi, M; Iyire, A; Mohammed, AR | 1 |
| Behari, A; Farooqui, A; Kapoor, VK; Mishra, K; Sharma, RK; Sinha, N | 1 |
| Gabriel, GV; Viviani, VR | 1 |
| Kjær, C; Nielsen, SB; Pedersen, BM; Stockett, MH | 1 |
| Asano, Y; Kameya, M | 1 |
| Derat, E; Driant, T; Nachon, F; Ollivier, C; Renard, PY | 1 |
| Cui, M; Fu, L; Li, M; Mi, J; Wang, Y; Xu, Y | 1 |
| Cao, DY; Du, Q; Jia, XL; Qi, JL; Qi, XR; Sun, WH; Xiang, B; Yan, X; Yang, LP; Yang, SK | 1 |
| Ding, Y; Hu, XJ; Liu, R | 1 |
| Chabert, V; Crochet, A; Fromm, KM; Hologne, M; Sénèque, O; Walker, O | 1 |
| Harada, N; Ikeda, K; Inagaki, N; Joo, E; Mano, F; Yamane, S | 1 |
| Mukhopadhyay, BP | 1 |
| Henzler-Wildman, KA; Morrison, EA; Robinson, AE; Thomas, NE; Werner, JP; Wu, C | 1 |
| Greenberg, MM; Yang, K | 1 |
| Alphonse Ignatius, A; Majumder, S; Wang, W | 1 |
| Alqhazo, M; Rashaid, AB | 1 |
| Echavarri-Erasun, C; Fajardo, AS; Legrand, P; Martin, L; Nicolet, Y; Payá-Tormo, LA; Pellicer Martı Nez, MT; Rubio, LM; Vernède, X | 1 |
| Brosnan, JT; Brosnan, ME | 1 |
| Fraser, ME; Huang, J | 1 |
| Bradbury, ARM; Jha, RK; Naranjo, L; Shabazz, K; Shin, SM; Strauss, CEM; Velappan, N; Yankey, A | 1 |
| Hörmann, P; John, H; Schrader, M; Thiermann, H | 1 |
| Chen, W; Hou, R; Li, Q; Liang, H; Yang, Y; Zhang, Y | 1 |
| Bao, H; Chang, L; Gou, S; Liu, H; Ni, J; Wu, X; Zhang, J; Zhang, Y | 1 |
| Bi, Y; Chen, G; Chen, L; Chen, Y; Dai, M; Deng, H; Du, R; Gao, Z; Hu, C; Hu, R; Huo, Y; Lai, S; Li, D; Li, M; Li, Q; Lin, H; Liu, C; Liu, R; Lu, J; Luo, Z; Mu, Y; Ning, G; Qin, G; Qin, Y; Shen, F; Shi, L; Su, Q; Tang, X; Wan, Q; Wang, G; Wang, J; Wang, S; Wang, T; Wang, W; Wang, X; Wang, Y; Wu, S; Xu, G; Xu, M; Xu, Y; Yan, L; Yang, T; Ye, Z; Yu, X; Zhang, D; Zhang, Y; Zhao, J; Zhao, X; Zhao, Z; Zheng, R | 1 |
| Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L | 1 |
| Bröer, S; Das, A; Gauthier-Coles, G; Rae, CD | 1 |
| Hu, D; Hu, L; Jiao, D; Li, G; Li, X; Li, Z; Liu, S; Qi, L; Wu, H; Zhao, C | 1 |
| Jia, W; Shi, L; Wang, X | 1 |
| Chen, J; Liu, HS; Liu, SB; Sa, RN; Tan, HZ; Wang, YM; Xie, JJ; Yu, Y; Zhao, F; Zou, Y | 1 |
| Oda, K; Wlodawer, A | 1 |
| Danchana, K; Kaneta, T; Umeda, MI; Yamashita, N | 1 |
| Duan, Y; Lai, J; Li, L; Shao, L; Wang, J; Wang, Y; Xing, X; Yang, Z | 1 |
| Liew, HJ; Liew, KS; Lim, LS; Teoh, CF; Tuzan, AD; Yong, AS | 1 |
7 review(s) available for glutamic acid and histidine
| Article | Year |
|---|---|
Mechanism of proton translocation by cytochrome c oxidase: a new four-stroke histidine cycle.
Topics: Animals; Copper; Electron Transport Complex IV; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Iron; Models, Chemical; Models, Molecular; Oxidation-Reduction; Protein Conformation; Proton-Motive Force; Protons | 2000 |
Synthetic analogs of zinc enzymes.
Topics: Alcohol Dehydrogenase; Amidohydrolases; Amino Acid Motifs; Aminopeptidases; Animals; Aspartic Acid; Bacterial Proteins; Bicarbonates; Binding Sites; Carbonic Anhydrases; Carboxypeptidases; Catalysis; Cations, Divalent; Cysteine; Dihydroorotase; DNA Repair; Enzymes; Escherichia coli Proteins; Glutamic Acid; Histidine; Ligands; Liver; Matrix Metalloproteinases; Metalloproteins; Models, Chemical; Molecular Structure; N-Acetylmuramoyl-L-alanine Amidase; Nitrates; O(6)-Methylguanine-DNA Methyltransferase; Porphobilinogen Synthase; Spectrum Analysis; Thermolysin; Transcription Factors; Water; Zinc | 2001 |
Amino acid catabolic pathways of lactic acid bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Asparagine; Aspartate Ammonia-Lyase; Aspartic Acid; Biodegradation, Environmental; Fermentation; Food Microbiology; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Histidine; Lactic Acid; Lactobacillus; Proline | 2006 |
Molecular basis of multidrug transport by ABC transporters.
Topics: Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Binding Sites; Crystallography, X-Ray; Glutamic Acid; Histidine; Humans; Lysine; Models, Biological; Molecular Sequence Data; Pharmaceutical Preparations; Protein Conformation; Protein Structure, Tertiary; Sequence Alignment | 2009 |
Designing hydrolytic zinc metalloenzymes.
Topics: Binding Sites; Carbonic Anhydrases; Catalysis; Catalytic Domain; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Hydrolysis; Metalloproteins; Models, Molecular; Protein Binding; Protein Engineering; Protein Structure, Secondary; Zinc; Zinc Fingers | 2014 |
Histidine Metabolism and Function.
Topics: Brain; Carnosine; Glutamic Acid; Histamine; Histidine; Histidine Ammonia-Lyase; Humans; Liver; Muscles; Skin | 2020 |
Overview of the Properties of Glutamic Peptidases That Are Present in Plant and Bacterial Pathogens and Play a Role in Celiac Disease and Cancer.
Topics: Asparagine; Bacteria; Celiac Disease; Glutamic Acid; Histidine; Humans; Neoplasms; Peptide Hydrolases | 2023 |
1 trial(s) available for glutamic acid and histidine
| Article | Year |
|---|---|
Calcium alpha-ketoglutarate administration to malnourished hemodialysis patients improves plasma arginine concentrations.
Topics: Adult; Aged; Arginine; Female; Follow-Up Studies; Glutamic Acid; Histidine; Humans; Ketoglutaric Acids; Kidney Failure, Chronic; Male; Middle Aged; Nutrition Disorders; Phosphates; Proline; Reference Values; Renal Dialysis; Time Factors; Urea | 1996 |
430 other study(ies) available for glutamic acid and histidine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis | 2002 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Topics: Amino Acid Transport Systems; Antiporters; Escherichia coli Proteins; HEK293 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Molecular Docking Simulation; Phenylalanine; Stereoisomerism; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2018 |
Mutations at Glu-32 and His-39 in the epsilon subunit of the Escherichia coli F1F0 ATP synthase affect its inhibitory properties.
Topics: Amino Acid Sequence; Base Sequence; Escherichia coli; Glutamates; Glutamic Acid; Histidine; Molecular Sequence Data; Mutagenesis, Insertional; Plasmids; Proton-Translocating ATPases | 1992 |
Characterization of two site-specifically mutated human dihydrolipoamide dehydrogenases (His-452----Gln and Glu-457----Gln).
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Dihydrolipoamide Dehydrogenase; Escherichia coli; Flavin-Adenine Dinucleotide; Genetic Vectors; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins | 1992 |
Proton transfer roles of lysine 64 and glutamic acid 64 replacing histidine 64 in the active site of human carbonic anhydrase II.
Topics: Binding Sites; Buffers; Carbonic Anhydrases; Cloning, Molecular; Escherichia coli; Glutamates; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Plasmids; Protons | 1992 |
The A14 position of insulin tolerates considerable structural alterations with modest effects on the biological behavior of the hormone.
Topics: Adipose Tissue; Alanine; Amino Acids; Animals; Cattle; Cycloleucine; Glucose; Glutamates; Glutamic Acid; Histidine; Insulin; Lipids; Liver; Lysine; Phenylalanine; Rats; Receptor, Insulin; Sheep; Structure-Activity Relationship; Swine; Tyrosine | 1992 |
The subcellular distribution of nickel in Ni-sensitive and Ni-resistant strains of Saccharomyces cerevisiae.
Topics: Amino Acids; Drug Resistance, Microbial; Glutamates; Glutamic Acid; Histidine; Lysine; Nickel; Saccharomyces cerevisiae; Vacuoles | 1992 |
Site-directed mutagenesis of conserved residues of Clostridium thermocellum endoglucanase CelC.
Topics: Amino Acid Sequence; Arginine; Asparagine; Cellulase; Clostridium; Glutamates; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Restriction Mapping | 1992 |
N-acetylhistidine, glutamate, and beta-alanine are concentrated in a receptor cell layer of the trout inner ear.
Topics: Animals; beta-Alanine; Carnosine; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hair Cells, Auditory; Histidine; Saccule and Utricle; Trout | 1991 |
X-ray structure of an unusual Ca2+ site and the roles of Zn2+ and Ca2+ in the assembly, stability, and storage of the insulin hexamer.
Topics: Animals; Binding Sites; Cadmium; Calcium; Glutamates; Glutamic Acid; Histidine; Insulin; Kinetics; Lead; Protein Conformation; Swine; X-Ray Diffraction; Zinc | 1991 |
Receptor sites for amino acids in the facial taste system of the channel catfish.
Topics: Action Potentials; Adaptation, Physiological; Alanine; Animals; Arginine; Electrophysiology; Glutamates; Glutamic Acid; Histidine; Ictaluridae; Lysine; Methionine; Proline; Receptors, Amino Acid; Receptors, Cell Surface; Stereoisomerism; Taste | 1991 |
Cellulase EGZ of Erwinia chrysanthemi: structural organization and importance of His98 and Glu133 residues for catalysis.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cellulase; Chromosome Deletion; Erwinia; Escherichia coli; Genes, Bacterial; Glutamates; Glutamic Acid; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Protein Conformation; Recombinant Proteins; Sequence Alignment | 1991 |
Involvement of the carboxy-terminal residue in the active site of the histidine-containing protein, HPr, of the phosphoenolpyruvate:sugar phosphotransferase system of Escherichia coli.
Topics: Bacterial Proteins; Base Sequence; Binding Sites; Binding Sites, Antibody; Escherichia coli; Glutamates; Glutamic Acid; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoenolpyruvate Sugar Phosphotransferase System; Protein Conformation; Substrate Specificity | 1991 |
Lipoamide dehydrogenase from Azotobacter vinelandii: site-directed mutagenesis of the His450-Glu455 diad. Spectral properties of wild type and mutated enzymes.
Topics: Azotobacter vinelandii; Binding Sites; Circular Dichroism; Cloning, Molecular; Dihydrolipoamide Dehydrogenase; Escherichia coli; Genetic Vectors; Glutamates; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Restriction Mapping | 1991 |
Histidine regulation of cyclic AMP metabolism in cultured renal epithelial LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Arginine Vasopressin; Aspartic Acid; Cells, Cultured; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Glutamates; Glutamic Acid; Histidine; Imidazoles; Indomethacin; Kidney; Swine | 1990 |
Site-directed mutagenesis of arginine 246, glutamic acid 247, and histidine 248 in the eukaryotic transcription factor S-II.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Chymotrypsin; Cloning, Molecular; Escherichia coli; Glutamates; Glutamic Acid; Histidine; Kinetics; Leucine; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Peptide Fragments; Plasmids; Recombinant Proteins; RNA Polymerase II; Transcription Factors; Transcription Factors, General; Transcriptional Elongation Factors | 1990 |
Stimulatory actions of bioflavonoids on tyrosine uptake into cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Biological Transport; Carbon Radioisotopes; Catecholamines; Cattle; Cells, Cultured; Chamomile; Flavones; Flavonoids; Glutamates; Glutamic Acid; Histidine; Lysine; Oils, Volatile; Plants, Medicinal; Quercetin; Serine; Tyrosine | 1990 |
Contribution of histidine residues to the conformational stability of ribonuclease T1 and mutant Glu-58----Ala.
Topics: Alanine; Enzyme Stability; Glutamates; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Mutation; Protein Conformation; Ribonuclease T1; Thermodynamics | 1990 |
Histidine-40 of ribonuclease T1 acts as base catalyst when the true catalytic base, glutamic acid-58, is replaced by alanine.
Topics: Alanine; Amino Acids; Catalysis; Escherichia coli; Esterification; Exoribonucleases; Glutamates; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mutation | 1990 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
Synaptic transmission in amphibian retinae during conditions unfavourable for calcium entry into presynaptic terminals.
Topics: Ambystoma; Animals; Bufo marinus; Calcium; Cobalt; Colforsin; Glutamates; Glutamic Acid; Histidine; In Vitro Techniques; Ion Channels; Retina; Synapses; Synaptic Transmission; Tetraethylammonium; Tetraethylammonium Compounds | 1986 |
Particular processing of pro-opiomelanocortin in Xenopus laevis intermediate pituitary. Sequencing of alpha- and beta-melanocyte-stimulating hormones.
Topics: Acetylation; alpha-MSH; Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Glutamates; Glutamic Acid; Histidine; Melanocyte-Stimulating Hormones; Molecular Sequence Data; Peptide Hydrolases; Pituitary Gland; Pro-Opiomelanocortin; Sequence Homology, Nucleic Acid; Xenopus laevis | 1989 |
Utilization of amino acids and peptides by Fusobacterium nucleatum.
Topics: Amino Acids; Aspartic Acid; Culture Media; Fusobacterium; Glutamates; Glutamic Acid; Histidine; Lysine; Methionine; Peptides | 1989 |
Effect of distance and orientation between arginine-302, histidine-322, and glutamate-325 on the activity of lac permease from Escherichia coli.
Topics: Arginine; Base Sequence; Cell Membrane; Escherichia coli; Escherichia coli Proteins; Glutamates; Glutamic Acid; Histidine; Kinetics; Lactose; Membrane Transport Proteins; Models, Molecular; Molecular Sequence Data; Monosaccharide Transport Proteins; Protein Conformation; Symporters | 1989 |
Short and long spacer sequences and other structural features of zinc binding sites in zinc enzymes.
Topics: Binding Sites; Enzymes; Glutamates; Glutamic Acid; Histidine; Ligands; Zinc | 1989 |
Histidine and proline are important sites of free radical damage to proteins.
Topics: Animals; Aspartic Acid; Free Radicals; Glutamates; Glutamic Acid; Histidine; In Vitro Techniques; Proline; Proteins | 1989 |
Site-specific alteration of Gly-24 in streptokinase: its effect on plasminogen activation.
Topics: Alanine; Base Sequence; Cloning, Molecular; Escherichia coli; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Molecular Weight; Mutation; Plasminogen; Radioimmunoassay; Streptokinase; Structure-Activity Relationship | 1989 |
Importance of amino acids on vasopressin-stimulated water flow.
Topics: Amino Acids; Animals; Bufonidae; Cyclic AMP; Diuresis; Drug Synergism; Female; Glutamates; Glutamic Acid; Histidine; Lysine; Methylation; Structure-Activity Relationship; Theophylline; Urinary Bladder; Vasopressins; Zinc | 1985 |
Isolation and characterization of a kappa amyloid fibril protein.
Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Animals; Antibody Formation; Electrophoresis, Polyacrylamide Gel; Female; Glutamates; Glutamic Acid; Histidine; Humans; Immunodiffusion; Isoleucine; Methionine; Middle Aged; Rabbits; Serine | 1985 |
Role of plasma membrane transport in hepatic glutamine metabolism.
Topics: Amino Acids; Animals; Biological Transport, Active; Cell Membrane; Cytosol; Glutamate-Ammonia Ligase; Glutamates; Glutamic Acid; Glutamine; Histidine; In Vitro Techniques; Liver; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Sodium | 1985 |
lac permease of Escherichia coli: histidine-322 and glutamic acid-325 may be components of a charge-relay system.
Topics: Binding Sites; Escherichia coli; Escherichia coli Proteins; Glutamates; Glutamic Acid; Histidine; Kinetics; Membrane Transport Proteins; Monosaccharide Transport Proteins; Mutation; Symporters | 1986 |
Huntington's disease: studies on brain free amino acids.
Topics: Adult; Aged; Aged, 80 and over; Amino Acids; Aspartic Acid; Brain; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Humans; Huntington Disease; Lysine; Male; Middle Aged; Putamen; Serine; Taurine | 1988 |
Interaction between Glu-219 and His-245 within the a subunit of F1F0-ATPase in Escherichia coli.
Topics: Amino Acid Sequence; Base Sequence; Escherichia coli; Genotype; Glutamates; Glutamic Acid; Histidine; Kinetics; Macromolecular Substances; Molecular Sequence Data; Plasmids; Protein Conformation; Proton-Translocating ATPases; Spectrometry, Fluorescence | 1988 |
Effects of amino acid substitutions at the active site in Escherichia coli beta-galactosidase.
Topics: Amino Acids; Bacteriophages; beta-Galactosidase; Binding Sites; Escherichia coli; Galactosidases; Glutamates; Glutamic Acid; Histidine; Methionine; Mutation; Plasmids; Restriction Mapping; Substrate Specificity; Tyrosine | 1988 |
L-histidine utilization in Aspergillus nidulans.
Topics: Ammonia-Lyases; Aspergillus nidulans; Biological Transport; Culture Media; Glutamates; Glutamic Acid; Glutamine; Histidine; Histidine Ammonia-Lyase; Nitrates; Quaternary Ammonium Compounds; Urocanic Acid | 1982 |
Human prostatic acid phosphatase: a histidine phosphatase.
Topics: Acid Phosphatase; Arginine; Aspartic Acid; Binding Sites; Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Male; Phosphotransferases; Prostate | 1982 |
Hemoglobin I (alpha 16(A14) Lys replaced by Glu) and hemoglobin J Iran (beta 77(EF1) His replaced by Asp) discovered in Japanese.
Topics: Aspartic Acid; Female; Globins; Glutamates; Glutamic Acid; Hemoglobin J; Hemoglobins; Hemoglobins, Abnormal; Histidine; Humans; Japan; Lysine; Male; Middle Aged | 1982 |
Evidence for the identification of synaptic transmitters released by photoreceptors of the toad retina.
Topics: Animals; Aspartic Acid; Bufo marinus; Cadaverine; Cells, Cultured; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Histidine; Neurotransmitter Agents; Photoreceptor Cells; Putrescine; Retina; Synapses; Time Factors | 1983 |
Abnormal amino acid concentrations in plasma and urine of experimentally diabetic dogs.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Arginine; Diabetes Mellitus, Experimental; Dogs; Female; Glutamates; Glutamic Acid; Histidine; Male; Phenylalanine; Renal Aminoacidurias; Tryptophan; Tyrosine | 1983 |
Use of designed metal-binding sites to study helix proximity in the lactose permease of Escherichia coli. 2. Proximity of helix IX (Arg302) with helix X (His322 and Glu325).
Topics: Amino Acid Sequence; Arginine; Binding Sites; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Manganese; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Protein Structure, Secondary; Symporters | 1995 |
E461H-beta-galactosidase (Escherichia coli): altered divalent metal specificity and slow but reversible metal inactivation.
Topics: beta-Galactosidase; Binding Sites; Cations, Divalent; Escherichia coli; Galactose; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Structural; Point Mutation; Recombinant Proteins; Substrate Specificity | 1995 |
Effect of the His175-->Glu mutation on the heme pocket architecture of cytochrome c peroxidase.
Topics: Amino Acid Sequence; Binding Sites; Cytochrome-c Peroxidase; Glutamic Acid; Heme; Histidine; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; X-Ray Diffraction | 1995 |
EPR studies of wild-type and several mutants of cytochrome c oxidase from Rhodobacter sphaeroides: Glu286 is not a bridging ligand in the cytochrome a3-CuB center.
Topics: Base Sequence; Copper; Cytochrome a Group; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Rhodobacter sphaeroides | 1995 |
Blood urea and amino acid concentrations in pigs of two breed combinations as affected by energy intakes.
Topics: Amino Acids; Animals; Aspartic Acid; Blood Urea Nitrogen; Chromatography, High Pressure Liquid; Crosses, Genetic; Diet; Energy Intake; Energy Metabolism; Glutamic Acid; Histidine; Lysine; Male; Swine; Tyrosine; Weight Gain | 1995 |
Roles of histidine 752 and glutamate 699 in the pH dependence of mouse band 3 protein-mediated anion transport.
Topics: Amino Acid Sequence; Animals; Anion Exchange Protein 1, Erythrocyte; Base Sequence; Binding Sites; Biological Transport; Chlorides; DNA Primers; Erythrocyte Membrane; Female; Glutamic Acid; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins; Xenopus laevis | 1995 |
Amino acid residues that influence the binding of manganese or calcium to photosystem II. 1. The lumenal interhelical domains of the D1 polypeptide.
Topics: Amino Acids; Aspartic Acid; Calcium; Cyanobacteria; Electron Transport; Glutamic Acid; Histidine; Light; Light-Harvesting Protein Complexes; Manganese; Mutagenesis, Site-Directed; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plastoquinone; Protein Structure, Secondary; Spectrometry, Fluorescence; Structure-Activity Relationship; Tyrosine | 1995 |
Amino acid residues that influence the binding of manganese or calcium to photosystem II. 2. The carboxy-terminal domain of the D1 polypeptide.
Topics: Amino Acids; Aspartic Acid; Calcium; Chlorophyll; Chlorophyll A; Cyanobacteria; Electron Transport; Glutamic Acid; Histidine; Kinetics; Light; Light-Harvesting Protein Complexes; Manganese; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Peptide Fragments; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plastoquinone; Structure-Activity Relationship; Water | 1995 |
Conservation of a common motif in enzymes catalyzing ADP-ribose transfer. Identification of domains in mammalian transferases.
Topics: Adenosine Diphosphate Ribose; Amino Acid Sequence; Animals; Base Sequence; Catalysis; DNA Primers; Glutamic Acid; Histidine; Molecular Sequence Data; Poly(ADP-ribose) Polymerases; Rabbits; Rats; Sequence Homology, Amino Acid | 1995 |
Cold lability of the mutant forms of Escherichia coli inorganic pyrophosphatase.
Topics: Aspartic Acid; Binding Sites; Cold Temperature; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Kinetics; Macromolecular Substances; Magnesium; Mutagenesis, Site-Directed; Pyrophosphatases; Structure-Activity Relationship | 1995 |
Site-directed mutagenesis of histidine 93, aspartic acid 180, glutamic acid 205, histidine 290, and aspartic acid 291 at the active site and tryptophan 279 at the raw starch binding site in barley alpha-amylase 1.
Topics: alpha-Amylases; Amino Acid Sequence; Aspartic Acid; Base Sequence; Binding Sites; Cloning, Molecular; DNA Primers; Glutamates; Glutamic Acid; Histidine; Hordeum; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Tryptophan | 1993 |
Copper(II) complexes of dipeptides containing aspartyl, glutamyl, and histidyl residues in the side chain.
Topics: Aspartic Acid; Copper; Dipeptides; Glutamates; Glutamic Acid; Histidine; Metals; Protein Binding | 1993 |
Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate.
Topics: Acetyl Coenzyme A; Alanine; Catalysis; Chloramphenicol; Chloramphenicol O-Acetyltransferase; Codon; Glutamates; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Molecular Structure; Mutagenesis, Site-Directed | 1994 |
Improved continuum electrostatic modelling in proteins, with comparison to experiment.
Topics: Amino Acid Sequence; Aspartic Acid; Bacillus; Binding Sites; Calcium; Electrochemistry; Glutamates; Glutamic Acid; Histidine; Mathematics; Models, Molecular; Mutagenesis, Site-Directed; Osmolar Concentration; Protein Conformation; Protein Folding; Recombinant Proteins; Solvents; Subtilisins | 1994 |
Role of alpha and beta carboxyl-terminal residues in the kinetics of human oxyhemoglobin dimer assembly.
Topics: Amino Acid Sequence; Arginine; Genetic Variation; Glutamates; Glutamic Acid; Heme; Hemoglobin A; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Oxyhemoglobins; Point Mutation; Spectrophotometry; Tyrosine; Valine | 1994 |
Catalysis by Syrian hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proposed roles of histidine 865, glutamate 558, and aspartate 766.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Catalysis; Cloning, Molecular; Cricetinae; Glutamates; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydroxymethylglutaryl CoA Reductases; Kinetics; Mesocricetus; Models, Theoretical; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Recombinant Proteins | 1994 |
Characterization of antimycin resistant mutants of Rhodospirillum rubrum.
Topics: Amino Acid Sequence; Antimycin A; Aspartic Acid; Cytochrome b Group; Drug Resistance, Microbial; Electron Transport Complex III; Genes, Fungal; Glutamates; Glutamic Acid; Histidine; Point Mutation; Rhodospirillum rubrum | 1994 |
[Influence of glutamic acid, histidine and arginine on dietary intake. Chemical structure and body mass composition of rats].
Topics: Animals; Arginine; Body Mass Index; Body Weight; Caseins; Eating; Food, Fortified; Glutamates; Glutamic Acid; Histidine; Male; Neurotransmitter Agents; Rats; Rats, Wistar; Reference Values | 1993 |
Crystal structure of RNase T1 complexed with the product nucleotide 3'-GMP. Structural evidence for direct interaction of histidine 40 and glutamic acid 58 with the 2'-hydroxyl group of the ribose.
Topics: Binding Sites; Crystallography, X-Ray; Glutamates; Glutamic Acid; Guanosine Monophosphate; Histidine; Hydrogen Bonding; Hydroxyl Radical; Isomerism; Models, Molecular; Molecular Sequence Data; Protein Conformation; Ribonuclease T1 | 1994 |
Histidine 326 is critical for the function of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain.
Topics: Amino Acid Transport System X-AG; Animals; Biological Transport; Brain; Glutamates; Glutamic Acid; Glycoproteins; Histidine; Models, Molecular; Mutation; Potassium; Proteolipids; Rats; Sodium; Structure-Activity Relationship | 1994 |
Short-term starvation alters the free amino acid content of the human intestinal mucosa.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Asparagine; Colon; Duodenum; Food; Glutamates; Glutamic Acid; Glutamine; Histidine; Humans; Intestinal Mucosa; Intestine, Large; Male; Starvation; Threonine; Time Factors | 1994 |
Two transthyretin mutations (glu42gly, his90asn) in an Italian family with amyloidosis.
Topics: Adult; Amyloid Neuropathies; Asparagine; Base Sequence; DNA Mutational Analysis; Female; Glutamic Acid; Glycine; Histidine; Humans; Male; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prealbumin | 1994 |
Effect of single-point mutations Phe41-->His and Phe143-->Glu on folding and catalytic properties of recombinant horseradish peroxidase expressed in E. coli.
Topics: Base Sequence; Binding Sites; Catalysis; Escherichia coli; Glutamic Acid; Heme; Histidine; Horseradish Peroxidase; Hydrogen Peroxide; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Protein Folding; Recombinant Proteins; Structure-Activity Relationship | 1994 |
Mutational analysis of the active site of RNase of Bacillus intermedius (BINASE).
Topics: Bacillus; Binding Sites; DNA Mutational Analysis; Endoribonucleases; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Structure-Activity Relationship | 1994 |
A mechanism of proton translocation by F1F0 ATP synthases suggested by double mutants of the a subunit.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Cattle; Consensus Sequence; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Proton-Translocating ATPases; Recombinant Proteins; Restriction Mapping; Sequence Homology, Amino Acid | 1994 |
p-Aminobenzoate synthesis in Escherichia coli: mutational analysis of three conserved amino acid residues of the amidotransferase PabA.
Topics: 4-Aminobenzoic Acid; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Binding, Competitive; Carbon-Carbon Lyases; Carbon-Nitrogen Ligases; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Glutamates; Glutamic Acid; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Homology, Amino Acid; Structure-Activity Relationship; Transaminases | 1993 |
Substitution of potential metal-coordinating amino acid residues in the zinc-binding site of endopeptidase-24.11.
Topics: Binding Sites; Glutamates; Glutamic Acid; Glycine; Histidine; Hydroxylamines; Kinetics; Metalloproteins; Models, Molecular; Mutagenesis, Site-Directed; Neprilysin; Recombinant Proteins; Structure-Activity Relationship; Zinc | 1993 |
Requirement of the C-terminal proline residue for stability of the Ca(2+)-activated photoprotein aequorin.
Topics: Aequorin; Animals; Base Sequence; Calcium; DNA; Electrophoresis, Agar Gel; Glutamates; Glutamic Acid; Histidine; Imidazoles; In Vitro Techniques; Luminescent Measurements; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Proline; Protein Biosynthesis; Pyrazines; Recombinant Proteins; Scyphozoa | 1993 |
Effect of different positively charged amino acids, C-terminally of the signal peptidase cleavage site, on the translocation kinetics of a precursor protein in Escherichia coli K-12.
Topics: Amino Acids; Arginine; Bacterial Outer Membrane Proteins; Bacterial Proteins; Base Sequence; Biological Transport; DNA, Bacterial; Electrochemistry; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Glutamates; Glutamic Acid; Histidine; Kinetics; Lysine; Membrane Proteins; Molecular Sequence Data; Porins; Protein Precursors; Serine Endopeptidases | 1993 |
Regulation of hypothalamic preprogrowth hormone-releasing factor messenger ribonucleic acid expression in food-deprived rats: a role for histaminergic neurotransmission.
Topics: Animals; Dietary Proteins; Food Deprivation; Gene Expression Regulation; Glutamates; Glutamic Acid; Growth Hormone-Releasing Hormone; Histamine; Histidine; Histidine Decarboxylase; Hypothalamus; Male; Methylhistidines; Neurotransmitter Agents; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tryptophan; Tyrosine | 1993 |
NMR studies of a complex of RNAse from Penicillium brevicompactum with dinucleoside phosphonate and the implications for the mechanism of enzyme action.
Topics: Aspergillus; Binding Sites; Dinucleoside Phosphates; Glutamates; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Penicillium; Ribonucleases | 1993 |
Role of Arg115 in the catalytic action of human lysozyme. X-ray structure of His115 and Glu115 mutants.
Topics: Arginine; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Glutamates; Glutamic Acid; Histidine; Humans; Hydrogen Bonding; Kinetics; Least-Squares Analysis; Models, Molecular; Muramidase; Mutation; Protein Conformation | 1993 |
A glutamic acid specific serine protease utilizes a novel histidine triad in substrate binding.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Glutamates; Glutamic Acid; Histidine; Models, Molecular; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine Endopeptidases; Streptomyces griseus; Substrate Specificity | 1993 |
[Production and catalytic properties of point mutants Phe41--->His and Phe143--->Glu of horseradish peroxidase, expressed in Escherichia coli].
Topics: Amino Acid Sequence; Base Sequence; Catalysis; Cloning, Molecular; DNA, Recombinant; Enzyme Stability; Escherichia coli; Glutamic Acid; Heme; Histidine; Horseradish Peroxidase; Molecular Sequence Data; Oxidation-Reduction; Phenylalanine; Point Mutation | 1995 |
The effect of hydrogen peroxide/L-histidine-induced DNA single- vs. double-strand breaks on poly(ADP-ribose)polymerase.
Topics: Animals; CHO Cells; Cricetinae; DNA; DNA-Directed DNA Polymerase; Glutamic Acid; Histidine; Hydrogen Peroxide; Time Factors | 1995 |
Interaction of substrate uridyl 3',5'-adenosine with ribonuclease A: a molecular dynamics study.
Topics: Animals; Binding Sites; Cattle; Dinucleoside Phosphates; Glutamic Acid; Glutamine; Histidine; Kinetics; Lysine; Models, Molecular; Molecular Conformation; Protein Conformation; Ribonuclease, Pancreatic | 1995 |
Glutamic acid 141 of the diphtheria toxin receptor (HB-EGF precursor) is critical for toxin binding and toxin sensitivity.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Diphtheria Toxin; DNA Primers; Glutamic Acid; Haplorhini; Heparin-binding EGF-like Growth Factor; Histidine; Humans; Intercellular Signaling Peptides and Proteins; Kinetics; Mice; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Protein Sorting Signals; Receptors, Cell Surface; Recombinant Fusion Proteins; Sequence Homology, Amino Acid | 1996 |
Physiological evidence for an interaction between Glu-325 and His-322 in the lactose carrier of Escherichia coli.
Topics: Base Sequence; Biological Transport; DNA Primers; Escherichia coli; Escherichia coli Proteins; Fermentation; Gene Expression Regulation, Bacterial; Glutamic Acid; Histidine; Kinetics; Lactose; Melibiose; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Point Mutation; Protons; Symporters | 1996 |
Tris(2,2'-bipyridyl)ruthenium(II)-mediated photoinduced electron transfer of engineered cytochrome P450 1A2.
Topics: 2,2'-Dipyridyl; Coordination Complexes; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Electron Transport; Glutamic Acid; Histidine; Kinetics; Light; Mutagenesis, Site-Directed; Oxidoreductases; Photosensitizing Agents; Protein Engineering; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry | 1996 |
Mechanism of interferon action: functionally distinct RNA-binding and catalytic domains in the interferon-inducible, double-stranded RNA-specific adenosine deaminase.
Topics: Adenosine Deaminase; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; DNA, Viral; Enzyme Induction; Glutamic Acid; Histidine; Humans; Interferons; Molecular Sequence Data; Mutagenesis, Site-Directed; RNA-Binding Proteins; RNA, Double-Stranded; Sequence Homology, Amino Acid; Structure-Activity Relationship | 1996 |
Studies on identifying the catalytic role of Glu-204 in the active site of yeast invertase.
Topics: Amino Acid Sequence; Bacteria; Base Sequence; beta-Fructofuranosidase; Binding Sites; Catalysis; Cysteine; Dithiothreitol; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Iodine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Plants; Point Mutation; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid | 1996 |
Functional site in alpha-lactalbumin encompasses a region corresponding to a subsite in lysozyme and parts of two adjacent flexible substructures.
Topics: Amino Acid Sequence; Conserved Sequence; DNA Primers; Glutamic Acid; Glutamine; Histidine; Isoleucine; Kinetics; Lactalbumin; Leucine; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Conformation; Protein Structure, Secondary; Valine | 1996 |
Mitochondrial phosphate transport protein. replacements of glutamic, aspartic, and histidine residues affect transport and protein conformation and point to a coupled proton transport path.
Topics: Amino Acid Sequence; Aspartic Acid; Carrier Proteins; Glutamic Acid; Histidine; Ion Transport; Molecular Sequence Data; Mutagenesis; Phosphate-Binding Proteins; Phosphates; Protein Conformation; Protons; Sequence Homology, Amino Acid | 1996 |
Active site properties of monomeric triosephosphate isomerase (monoTIM) as deduced from mutational and structural studies.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Catalysis; Chickens; Circular Dichroism; Enzyme Inhibitors; Fungal Proteins; Glutamic Acid; Glycolates; Histidine; Hydroxamic Acids; Kinetics; Lysine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protozoan Proteins; Saccharomyces cerevisiae; Species Specificity; Structure-Activity Relationship; Substrate Specificity; Triose-Phosphate Isomerase; Trypanosoma | 1996 |
Woodward's reagent K inactivation of Escherichia coli L-threonine dehydrogenase: increased absorbance at 340-350 nm is due to modification of cysteine and histidine residues, not aspartate or glutamate carboxyl groups.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Cysteine; Enzyme Inhibitors; Escherichia coli; Glutamic Acid; Histidine; Isoxazoles; Kinetics; Models, Chemical; Molecular Sequence Data; Solvents; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1996 |
Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Sequence; Base Sequence; Binding Sites; Chromatography, Ion Exchange; Cloning, Molecular; Conserved Sequence; Cysteine; DNA Helicases; DNA Probes; Escherichia coli; Fungal Proteins; Glutamic Acid; Histidine; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; RNA Helicases; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Trans-Activators | 1996 |
The specificity of the neuroendocrine convertase PC3 is determined by residues NH2- and COOH-terminal to the cleavage site.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid Endopeptidases; Binding Sites; Glutamic Acid; Histidine; Molecular Sequence Data; Prealbumin; Proprotein Convertases; Recombinant Proteins; Serine Proteinase Inhibitors; Substrate Specificity | 1996 |
The distal glutamic acid as an acid-base catalyst in the distal site of horseradish peroxidase.
Topics: Amino Acid Sequence; Binding Sites; Chloride Peroxidase; Glutamic Acid; Guaiacol; Heme; Histidine; Horseradish Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Oxidation-Reduction; Polymerase Chain Reaction; Recombinant Proteins; Spectrophotometry | 1996 |
Location of the active site and proposed catalytic mechanism of pterin-4a-carbinolamine dehydratase.
Topics: Amino Acid Sequence; Binding Sites; Glutamic Acid; Histidine; Humans; Hydro-Lyases; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Pteridines; Quinones; Recombinant Proteins; Structure-Activity Relationship; Transcription Factors | 1996 |
Importance of the gamma-carboxyl group of glutamate-462 of the large alpha-subunit for the catalytic function and the stability of the multienzyme complex of fatty acid oxidation from Escherichia coli.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Binding Sites; Carbon-Carbon Double Bond Isomerases; DNA Primers; Enoyl-CoA Hydratase; Enzyme Stability; Escherichia coli; Gene Expression; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Isomerases; Kinetics; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Denaturation; Racemases and Epimerases; Temperature | 1997 |
Primary structure and functional analysis of the soluble transducer protein HtrXI in the archaeon Halobacterium salinarium.
Topics: Amino Acid Sequence; Archaeal Proteins; Aspartic Acid; Chemotaxis; Cloning, Molecular; Genes, Bacterial; Glutamic Acid; Halobacterium; Histidine; Methyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Deletion; Signal Transduction; Solubility; Zinc Fingers | 1997 |
Role of histidyl residues in the binding of ligands to the porcine N-methyl-D-aspartate receptor.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Cerebral Cortex; Diethyl Pyrocarbonate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Histidine; Ionophores; Kainic Acid; Ligands; N-Methylaspartate; Piperazines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Swine; Synaptic Membranes; Tritium | 1997 |
Catalytic activities and structural properties of horseradish peroxidase distal His42 --> Glu or Gln mutant.
Topics: Catalysis; Glutamic Acid; Glutamine; Histidine; Horseradish Peroxidase; Mutagenesis, Site-Directed; Spectrum Analysis, Raman; Structure-Activity Relationship; Styrenes; Sulfides | 1997 |
Subunit and amino acid interactions in the Escherichia coli mannitol permease: a functional complementation study of coexpressed mutant permease proteins.
Topics: Binding Sites; Biological Transport; Dimerization; Escherichia coli; Escherichia coli Proteins; Fermentation; Genetic Complementation Test; Glutamic Acid; Histidine; Mannitol; Monosaccharide Transport Proteins; Mutation; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation | 1997 |
pH titration studies of an SH2 domain-phosphopeptide complex: unusual histidine and phosphate pKa values.
Topics: Amides; Amino Acid Sequence; Animals; Cattle; Glutamic Acid; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Peptide Fragments; Phosphates; Phosphoproteins; Phosphotyrosine; Protein Structure, Secondary; Receptor, Platelet-Derived Growth Factor beta; Receptors, Platelet-Derived Growth Factor; Sulfhydryl Compounds; Type C Phospholipases | 1997 |
Bound water in the proton translocation mechanism of the haem-copper oxidases.
Topics: Amino Acid Sequence; Binding Sites; Cloning, Molecular; Conserved Sequence; Copper; Cytochrome b Group; Cytochromes; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Heme; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ion Channels; Ligands; Models, Chemical; Models, Molecular; Models, Statistical; Oxidation-Reduction; Protein Conformation; Protons; Water | 1997 |
Fourier transform infrared evidence for connectivity between CuB and glutamic acid 286 in cytochrome bo3 from Escherichia coli.
Topics: Copper; Cytochrome b Group; Cytochromes; Dimerization; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Hydrogen Bonding; Ligands; Mutagenesis, Site-Directed; Photolysis; Spectroscopy, Fourier Transform Infrared | 1997 |
Glutamate-286 mutants of cytochrome bo-type ubiquinol oxidase from Escherichia coli: influence of mutations on the binuclear center structure revealed by FT-IR and EPR spectroscopies.
Topics: Binding Sites; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Escherichia coli; Glutamic Acid; Histidine; Mutagenesis, Site-Directed; Oxidation-Reduction; Point Mutation; Proline; Protein Conformation; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared | 1997 |
Replacement of the active site tyrosine of vaccinia DNA topoisomerase by glutamate, cysteine or histidine converts the enzyme into a site-specific endonuclease.
Topics: Binding Sites; Cysteine; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Endonucleases; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mutagenesis; Structure-Activity Relationship; Tyrosine; Vaccinia virus | 1998 |
A conserved histidine is essential for glycerolipid acyltransferase catalysis.
Topics: Acyltransferases; Alanine; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Cell Membrane; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression; Genetic Complementation Test; Glutamic Acid; Glycerol-3-Phosphate O-Acyltransferase; Histidine; Molecular Sequence Data; Plasmids; Polymerase Chain Reaction; Protein Biosynthesis; Sequence Alignment; Sequence Analysis, DNA; Transcription, Genetic | 1998 |
Lysine and arginine residues in the N-terminal 18% of apolipoprotein B are critical for its binding to microsomal triglyceride transfer protein.
Topics: Apolipoproteins B; Arginine; Aspartic Acid; Binding Sites; Carrier Proteins; Cell Line; Glutamic Acid; Heparin; Histidine; Humans; Lysine; Microsomes; Protein Binding; Receptors, LDL | 1998 |
Free amino acids in milks of human subjects, other primates and non-primates.
Topics: Amino Acids; Animals; Caniformia; Cattle; Elephants; Glutamic Acid; Gorilla gorilla; Histidine; Horses; Humans; Milk; Milk, Human; Pan troglodytes; Sheep; Species Specificity; Swine; Taurine | 1998 |
A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor.
Topics: Alleles; Amino Acid Sequence; Animals; Aspartic Acid; Cattle; Conserved Sequence; Foxes; Genes, Dominant; Glutamic Acid; Hair Color; Histidine; Ligands; Lysine; Mice; Models, Genetic; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Receptors, Corticotropin; Receptors, Melanocortin; Sheep | 1998 |
Spectroscopic evidence for interaction between transmembrane helices 3 and 5 in rhodopsin.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; Cattle; Glutamic Acid; Glutamine; Histidine; Membrane Proteins; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Protein Structure, Secondary; Rhodopsin; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Transducin | 1998 |
The mechanism of adenosylmethionine-dependent activation of methionine synthase: a rapid kinetic analysis of intermediates in reductive methylation of Cob(II)alamin enzyme.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Substitution; Aspartic Acid; Cobalt; Electron Transport; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Methylation; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; S-Adenosylmethionine; Transcobalamins; Vitamin B 12 | 1998 |
The active site structure of tetanus neurotoxin resolved by multiple scattering analysis in X-Ray absorption spectroscopy.
Topics: Absorptiometry, Photon; Animals; Binding Sites; Crystallography, X-Ray; Glutamic Acid; Histidine; Metalloendopeptidases; Neurotoxins; Tetanus Toxin; Thermolysin; Tyrosine; Zinc | 1998 |
Thimet oligopeptidase: site-directed mutagenesis disproves previous assumptions about the nature of the catalytic site.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Enzyme Activation; Gene Expression Regulation, Enzymologic; Glutamic Acid; Histidine; Ligands; Metalloendopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Recombinant Proteins; Zinc | 1998 |
Toxin binding site of the diphtheria toxin receptor: loss and gain of diphtheria toxin binding of monkey and mouse heparin-binding, epidermal growth factor-like growth factor precursors by reciprocal site-directed mutagenesis.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Binding Sites; Cell Line; Diphtheria Toxin; Epidermal Growth Factor; Glutamic Acid; Haplorhini; Heparin-binding EGF-like Growth Factor; Histidine; Inhibitory Concentration 50; Intercellular Signaling Peptides and Proteins; Isoleucine; Membrane Glycoproteins; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Precursors; Receptors, Cell Surface; Sequence Alignment; Tetraspanin 29; Transfection | 1998 |
A single amino acid, glu146, governs the substrate specificity of a human dopamine sulfotransferase, SULT1A3.
Topics: Amino Acid Sequence; Arylsulfotransferase; Binding Sites; Cloning, Molecular; Glutamic Acid; Histidine; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Substrate Specificity | 1998 |
Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Asparagine; Carrier Proteins; Cell Membrane; Glutamic Acid; Histidine; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Piperidines; Saccharomyces cerevisiae; Steroid Isomerases; Threonine; Tryptophan | 1999 |
Site-directed mutagenesis of charged and potentially proton-carrying residues in the beta subunit of the proton-translocating nicotinamide nucleotide transhydrogenase from Escherichia coli. Characterization of the beta H91, beta D392, and beta K424 mutant
Topics: Aspartic Acid; Biological Transport; Catalysis; Conserved Sequence; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Lysine; Magnesium Chloride; Mutagenesis, Site-Directed; NADP; NADP Transhydrogenases; Proton Pumps; Recombinant Proteins; Sodium Chloride | 1999 |
Role of the buried glutamate in the alpha-helical coiled coil domain of the macrophage scavenger receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Cattle; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Macrophages; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Conformation; Protein Structure, Secondary; Rabbits; Receptors, Immunologic; Receptors, Scavenger; Sequence Analysis; Valine | 1999 |
Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities.
Topics: Amino Acids; Animals; Aryldialkylphosphatase; Aspartic Acid; Binding Sites; Bromosuccinimide; Calcium Radioisotopes; Cell Line; Dicyclohexylcarbodiimide; Diethyl Pyrocarbonate; Enzyme Activation; Enzyme Inhibitors; Esterases; Glutamic Acid; Glycosylation; Histidine; Humans; Indicators and Reagents; Kidney; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Rabbits; Recombinant Proteins; Spectrometry, Fluorescence; Terbium; Tryptophan | 1999 |
Mutations at four active site residues of biotin carboxylase abolish substrate-induced synergism by biotin.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Arginine; Asparagine; Binding Sites; Biotin; Carbon-Nitrogen Ligases; Drug Synergism; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Magnesium; Mutagenesis, Site-Directed; Peptides; Plasmids; Substrate Specificity | 1999 |
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase.
Topics: Alanine Racemase; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Geobacillus stearothermophilus; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Mutagenesis, Site-Directed; Protons; Pyridoxal Phosphate; Schiff Bases; Solvents; Tyrosine | 1999 |
Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants.
Topics: Asparagine; Binding Sites; Cholesterol Oxidase; Crystallography, X-Ray; Flavin-Adenine Dinucleotide; Glutamic Acid; Glutamine; Histidine; Models, Molecular; Mutagenesis, Site-Directed; Streptomyces; Structure-Activity Relationship; Substrate Specificity; Water | 1999 |
Site-directed mutants of charged residues in the active site of tyrosine hydroxylase.
Topics: Amino Acid Substitution; Arginine; Aspartic Acid; Binding Sites; Conserved Sequence; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Tyrosine 3-Monooxygenase | 1999 |
The roles of Glu-327 and His-446 in the bisphosphatase reaction of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase probed by NMR spectroscopic and mutational analyses of the enzyme in the transient phosphohistidine intermediate complex.
Topics: Alanine; Animals; DNA Mutational Analysis; Fructose-Bisphosphatase; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Multienzyme Complexes; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Phosphofructokinase-1; Phosphofructokinase-2; Rats; Testis; Titrimetry | 1999 |
Distinct molecular bases for pH sensitivity of the guard cell K+ channels KST1 and KAT1.
Topics: Animals; Arabidopsis Proteins; Base Sequence; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ion Channel Gating; Mutagenesis, Site-Directed; Plant Proteins; Potassium Channels; Potassium Channels, Inwardly Rectifying; Recombinant Proteins; Xenopus | 1999 |
Double-mutant analysis of the interaction of Ras with the Ras-binding domain of RGL.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Glutamic Acid; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Histidine; Humans; Lysine; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Protein Binding; ras Proteins; Rats; Recombinant Fusion Proteins; Static Electricity; Tyrosine | 1999 |
Identification of metal ligands in the Clostridium histolyticum ColH collagenase.
Topics: Amino Acid Sequence; Asparagine; Bacterial Proteins; Base Sequence; Catalytic Domain; Clostridium; Collagenases; Glutamic Acid; Histidine; Kinetics; Ligands; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Zinc | 1999 |
Structural and spectral response of green fluorescent protein variants to changes in pH.
Topics: Amino Acid Substitution; Animals; Crystallography, X-Ray; Glutamic Acid; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Luminescent Proteins; Mutagenesis, Site-Directed; Pigments, Biological; Protons; Scyphozoa; Serine; Spectrometry, Fluorescence; Structure-Activity Relationship; Threonine | 1999 |
Zinc coordination and substrate catalysis within the neuropeptide processing enzyme endopeptidase EC 3.4.24.15. Identification of active site histidine and glutamate residues.
Topics: Animals; Bacteria; Binding Sites; Catalysis; Chelating Agents; Chlorides; Circular Dichroism; DNA Primers; Enzyme Inhibitors; Glutamic Acid; Histidine; Kinetics; Metalloendopeptidases; Mutagenesis, Site-Directed; Oligopeptides; Protein Conformation; Rats; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Zinc; Zinc Compounds | 1999 |
EXAFS study of zinc coordination in bacitracin A.
Topics: Amines; Bacitracin; Electron Probe Microanalysis; Glutamic Acid; Histidine; Ligands; Nitrogen; Oxygen; Sulfur; Thiazoles; Water; Zinc | 1999 |
Significant enhancement in the binding of p-nitrophenyl-beta-D-xylobioside by the E128H mutant F/10 xylanase from Streptomyces olivaceoviridis E-86.
Topics: Disaccharides; Endo-1,4-beta Xylanases; Glutamic Acid; Histidine; Kinetics; Mutagenesis, Site-Directed; Streptomyces; Xylosidases | 1999 |
Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Manganese; Membrane Transport Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Spectrometry, Fluorescence; Spin Labels; Symporters | 1999 |
The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme.
Topics: Amino Acid Sequence; Animals; Catalysis; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; DNA, Complementary; Enzyme Activation; Escherichia coli; Glutamic Acid; Histidine; Humans; Leucine; Liver; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Rats; Recombinant Proteins; Zinc | 1999 |
Proton NMR investigation of the heme active site structure of an engineered cytochrome c peroxidase that mimics manganese peroxidase.
Topics: Arginine; Aspartic Acid; Binding Sites; Cyanides; Cytochrome-c Peroxidase; Glutamic Acid; Glycine; Heme; Histidine; Leucine; Molecular Mimicry; Nuclear Magnetic Resonance, Biomolecular; Peroxidases; Protein Engineering; Protons; Spectrophotometry; Valine | 1999 |
Transport of amino acids and ammonium in mycelium of Agaricus bisporus.
Topics: Agaricus; Amino Acids; Arginine; Biological Transport; Carbon Radioisotopes; Culture Media; Glutamic Acid; Glutamine; Histidine; Kinetics; Lysine; Methylamines; Quaternary Ammonium Compounds | 1999 |
Characterization of residues in human IgE and IgG binding site by chemical modification of ovomucoid third domain.
Topics: Acylation; Alkylation; Aspartic Acid; Binding Sites; Child, Preschool; Circular Dichroism; Female; Glutamic Acid; Histidine; Humans; Immunoglobulin E; Immunoglobulin G; Infant; Lysine; Ovomucin; Protein Structure, Secondary; Structure-Activity Relationship; Tetranitromethane; Tyrosine | 1999 |
Extracellular glutamate in the dorsal horn of the lumbar spinal cord in the freely moving rat during hindlimb stepping.
Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Extracellular Space; Female; Glutamic Acid; Hindlimb; Histidine; Locomotion; Microdialysis; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Spinal Cord | 1999 |
Mutants that alter the covalent structure of catalase hydroperoxidase II from Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Catalase; Crystallography, X-Ray; Cysteine; Escherichia coli; Genetic Variation; Glutamic Acid; Heme; Histidine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins; Restriction Mapping | 1999 |
Role of histidine-50, glutamic acid-96, and histidine-137 in the ribonucleolytic mechanism of the ribotoxin alpha-sarcin.
Topics: Aspergillus; Catalytic Domain; Circular Dichroism; Cytotoxins; Endoribonucleases; Escherichia coli; Fungal Proteins; Glutamic Acid; Histidine; Magnetic Resonance Spectroscopy; Molecular Conformation; Mutagenesis, Site-Directed; Recombinant Proteins; Spectrometry, Fluorescence | 1999 |
Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface.
Topics: Amino Acid Substitution; Arginine; Asparagine; Circular Dichroism; Glutamic Acid; Glutamine; Histidine; Linear Models; Lysine; Mutagenesis, Site-Directed; Protein Engineering; Protein Folding; Static Electricity; Surface Properties; Thermodynamics; Ubiquitins | 1999 |
Selectively 2H-labeled Glu/Asp: application to pKa measurements in Abeta amyloid peptides.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Aspartic Acid; Deuterium; Glutamic Acid; Histidine; Isotope Labeling; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Protein Conformation | 2000 |
Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release.
Topics: Binding Sites; Crystallography, X-Ray; Dipeptides; Glutamic Acid; Histidine; Humans; Iron; Mutagenesis, Site-Directed; Protein Binding; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Transferrin | 2000 |
Slow formation of [3Fe-4S](1+) clusters in mutant forms of Desulfovibrio africanus ferredoxin III.
Topics: Amino Acid Substitution; Aspartic Acid; Desulfovibrio; Electron Spin Resonance Spectroscopy; Ferredoxins; Genetic Variation; Glutamic Acid; Histidine; Iron-Sulfur Proteins; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Recombinant Proteins; Spectrophotometry | 2000 |
Investigation of spectroscopic intermediates during copper-binding and TPQ formation in wild-type and active-site mutants of a copper-containing amine oxidase from yeast.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Binding Sites; Coenzymes; Copper; Cysteine; Dihydroxyphenylalanine; Glutamic Acid; Glutamine; Histidine; Mutagenesis, Site-Directed; Oxygen Consumption; Pichia; Recombinant Proteins; Spectrophotometry, Atomic; Spectrophotometry, Ultraviolet | 2000 |
Endonuclease activity in lipocalins.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Carrier Proteins; Cations, Divalent; Cattle; Circular Dichroism; Conserved Sequence; DNA; Endonucleases; Glutamic Acid; Histidine; Humans; Hydrolysis; Lactoglobulins; Lipocalin 1; Molecular Sequence Data; Protein Structure, Secondary; Retinol-Binding Proteins; Sequence Alignment; Serratia marcescens | 2000 |
Remarkable thermal stability of doubly intramolecularly cross-linked hen lysozyme.
Topics: Amino Acid Substitution; Animals; Binding Sites; Calorimetry, Differential Scanning; Chickens; Egg White; Enzyme Stability; Glutamic Acid; Histidine; Hot Temperature; Lysine; Muramidase; Mutagenesis, Site-Directed; Protein Folding; Recombinant Proteins; Thermodynamics; Tryptophan | 2000 |
Deterministic features of side-chain main-chain hydrogen bonds in globular protein structures.
Topics: Amino Acids; Asparagine; Aspartic Acid; Crystallization; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Protein Conformation; Protein Structure, Secondary; Proteins; Serine; Threonine | 2000 |
Identification of key amino acid residues in Neisseria polysaccharea amylosucrase.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Base Sequence; Binding Sites; Catalysis; Glucosyltransferases; Glutamic Acid; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Neisseria; Sequence Alignment; Structure-Activity Relationship | 2000 |
Copper catalyzed oxidation of Alzheimer Abeta.
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Arginine; Catalysis; Chromatography, High Pressure Liquid; Copper; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen Peroxide; Iron; Oxidation-Reduction; Oxygen; Peptide Fragments; Protein Processing, Post-Translational; Time Factors; Tyrosine | 2000 |
Conformational stability changes of the amino terminal domain of enzyme I of the Escherichia coli phosphoenolpyruvate: sugar phosphotransferase system produced by substituting alanine or glutamate for the active-site histidine 189: implications for phosph
Topics: Alanine; Amino Acid Substitution; Binding Sites; Calorimetry, Differential Scanning; Escherichia coli; Glutamic Acid; Histidine; Models, Molecular; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Phosphotransferases (Nitrogenous Group Acceptor); Protein Conformation; Protein Denaturation; Thermodynamics | 2000 |
A structure-function study of a proton transport pathway in the gamma-class carbonic anhydrase from Methanosarcina thermophila.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Biological Transport; Carbonic Anhydrases; Cysteine; Deuterium; Escherichia coli; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Methanosarcina; Mutagenesis, Site-Directed; Protons; Serine; Solvents; Structure-Activity Relationship; Threonine; Tryptophan | 2000 |
Site-directed mutagenesis studies of human A(2A) adenosine receptors: involvement of glu(13) and his(278) in ligand binding and sodium modulation.
Topics: Animals; Binding, Competitive; Drug Interactions; Glutamic Acid; Guanosine Triphosphate; Histidine; Humans; In Vitro Techniques; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sodium; Triazines; Triazoles; Tritium | 2000 |
Mechanism of the bisphosphatase reaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase probed by (1)H-(15)N NMR spectroscopy.
Topics: Allosteric Regulation; Animals; Catalytic Domain; Enzyme Activation; Fructosediphosphates; Glutamic Acid; Histidine; Hydrogen Bonding; Liver; Models, Chemical; Models, Molecular; Multienzyme Complexes; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phosphofructokinase-2; Phosphoric Monoester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Protein Processing, Post-Translational; Protons; Rats | 2000 |
Swarming of Pseudomonas aeruginosa is dependent on cell-to-cell signaling and requires flagella and pili.
Topics: Aspartic Acid; Bacterial Proteins; Culture Media; Decanoates; Disaccharides; DNA-Binding Proteins; Fimbriae Proteins; Fimbriae, Bacterial; Flagella; Flagellin; Glutamic Acid; Histidine; Microscopy, Electron; Movement; Mutation; Nitrogen; Proline; Pseudomonas aeruginosa; Rhamnose; Signal Transduction; Surface-Active Agents; Trans-Activators; Transcription Factors | 2000 |
The structure of aspartyl dipeptidase reveals a unique fold with a Ser-His-Glu catalytic triad.
Topics: Catalytic Domain; Crystallography, X-Ray; Dipeptidases; Glutamic Acid; Histidine; Models, Molecular; Protein Structure, Secondary; Salmonella typhimurium; Serine | 2000 |
An examination of the role of asp-177 in the His-Asp catalytic dyad of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: X-ray structure and pH dependence of kinetic parameters of the D177N mutant enzyme.
Topics: Aspartic Acid; Catalytic Domain; Crystallography, X-Ray; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Leuconostoc; Models, Chemical; Models, Molecular; Movement; Mutagenesis, Site-Directed; Mutation | 2000 |
Construction of a high affinity zinc binding site in the metabotropic glutamate receptor mGluR1: noncompetitive antagonism originating from the amino-terminal domain of a family C G-protein-coupled receptor.
Topics: Alanine; Animals; Binding Sites; Blotting, Western; Cell Line; Cell Membrane; Chlorides; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Glutamic Acid; Histidine; Humans; Immunoblotting; Inhibitory Concentration 50; Inositol Phosphates; Ions; Kinetics; Ligands; Lysine; Models, Molecular; Mutation; Plasmids; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Metabotropic Glutamate; Transfection; Zinc; Zinc Compounds | 2001 |
Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site.
Topics: Alanine; Amidohydrolases; Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Binding Sites; Cations, Divalent; Conserved Sequence; Escherichia coli; Glutamic Acid; Gram-Negative Bacteria; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Zinc | 2001 |
Direct evidence for the protonation of aspartate-75, proposed to be at a quinol binding site, upon reduction of cytochrome bo3 from Escherichia coli.
Topics: Amides; Aspartic Acid; Binding Sites; Cytochrome b Group; Cytochromes; Electrochemistry; Electron Transport Complex IV; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Protons; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Ubiquinone | 2001 |
Zinc and copper bind to unique sites of histatin 5.
Topics: Aspartic Acid; Copper; Glutamic Acid; Histatins; Histidine; Humans; Ligands; Magnetic Resonance Spectroscopy; Protein Binding; Salivary Proteins and Peptides; Zinc | 2001 |
Topology and structure of the C1q-binding site on C-reactive protein.
Topics: Amino Acid Substitution; Asparagine; Binding Sites; C-Reactive Protein; Complement Activation; Complement C1q; Glutamic Acid; Histidine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylcholine; Polysaccharides, Bacterial; Serum Albumin, Bovine; Streptococcus pneumoniae; Threonine; Tyrosine | 2001 |
Biochemical analysis of point mutations in the 5'-3' exonuclease of DNA polymerase I of Streptococcus pneumoniae. Functional and structural implications.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Conserved Sequence; DNA; DNA Polymerase I; DNA, Single-Stranded; Dose-Response Relationship, Drug; Exodeoxyribonuclease V; Exodeoxyribonucleases; Glutamic Acid; Histidine; Kinetics; Ligands; Magnesium Chloride; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Streptococcus pneumoniae | 2001 |
Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants.
Topics: Asparagine; Binding Sites; Calorimetry; Carbonic Anhydrases; Cations, Divalent; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen Bonding; Ligands; Mutagenesis, Site-Directed; Protein Binding; Thermodynamics; Zinc | 2001 |
Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase of riboflavin biosynthesis.
Topics: Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Dimerization; Escherichia coli; Glutamic Acid; Histidine; Intramolecular Transferases; Magnesium; Models, Chemical; Models, Molecular; Protein Structure, Secondary; Riboflavin; Riboflavin Synthase | 2001 |
Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites.
Topics: Animals; Binding Sites; Carrier Proteins; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Glutamic Acid; Histidine; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Engineering; Protein Structure, Tertiary; Structure-Activity Relationship; Zinc | 2001 |
Electrically induced release of labelled taurine, alpha- and beta-alanine, glycine, glutamate and other amino acids from rat neocortical slices in vitro.
Topics: Alanine; Animals; Aspartic Acid; Carnosine; Electric Stimulation; Glutamic Acid; Glycine; Histidine; Neocortex; Neurons; Organ Culture Techniques; Rats; Serine; Taurine; Tritium | 1976 |
Active site residues of glutamate racemase.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Asparagine; Aspartic Acid; Bacterial Proteins; Binding Sites; Deuterium; Glutamic Acid; Glutamine; Histidine; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Alignment | 2001 |
Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
Topics: Alanine; Binding Sites; Catalytic Domain; Conserved Sequence; Crystallization; Crystallography, X-Ray; Cytomegalovirus; Dimerization; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine; Serine Endopeptidases; Solvents | 2001 |
Lovastatin biosynthesis by Aspergillus terreus in a chemically defined medium.
Topics: Anticholesteremic Agents; Aspergillus; Culture Media; Fermentation; Glucose; Glutamic Acid; Histidine; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin | 2001 |
Catalytic acid-base groups in yeast pyruvate decarboxylase. 1. Site-directed mutagenesis and steady-state kinetic studies on the enzyme with the D28A, H114F, H115F, and E477Q substitutions.
Topics: Alanine; Amino Acid Substitution; Aspartic Acid; Carbon Dioxide; Catalysis; Catalytic Domain; Cloning, Molecular; DNA, Recombinant; Enzyme Activation; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Pyruvate Decarboxylase; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Thiamine Pyrophosphate | 2001 |
Glutamate 170 of human l-3-hydroxyacyl-CoA dehydrogenase is required for proper orientation of the catalytic histidine and structural integrity of the enzyme.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Binding Sites; Catalysis; Crystallography, X-Ray; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Molecular; Protein Binding; Time Factors | 2001 |
Mechanism of specific target recognition and RNA hydrolysis by ribonucleolytic toxin restrictocin.
Topics: Allergens; Animals; Antigens, Plant; Arginine; Circular Dichroism; Escherichia coli; Fungal Proteins; Glutamic Acid; HeLa Cells; Histidine; Humans; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Mycotoxins; Protein Synthesis Inhibitors; Rabbits; Recombinant Proteins; Reticulocytes; Ribonucleases; RNA, Ribosomal, 28S; Substrate Specificity; Tyrosine | 2001 |
Disruption of histidine catabolism in NEUT2 mice.
Topics: Animals; Cytosol; Genotype; Glutamic Acid; Heterozygote; Histidine; Homozygote; Liver; Mice; Mice, Knockout; Models, Chemical; Oxygen; Transaminases; Urocanic Acid | 2001 |
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase; Aspartic Acid; Binding Sites; Carboxy-Lyases; Catalysis; Chromatography; Cysteine; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myristic Acid; Plasmids; Protein Binding; Recombinant Proteins | 2001 |
Determination of amino acids by ion-exchange chromatography on filter paper spotted blood samples stored at different temperatures and for different periods: comparison with capillary and venous blood.
Topics: Adolescent; Adult; Age Factors; Amino Acids; Blood Specimen Collection; Capillaries; Chromatography, Ion Exchange; Cold Temperature; Cystine; Glutamic Acid; Histidine; Humans; Methionine; Ornithine; Paper; Reproducibility of Results; Serine; Temperature; Veins | 2001 |
Substitution of aspartate and glutamate for active center histidines in the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system maintain phosphotransfer potential.
Topics: Aspartic Acid; Bacterial Proteins; Escherichia coli; Glutamic Acid; Histidine; Phosphoenolpyruvate Sugar Phosphotransferase System; Phosphorylation; Structure-Activity Relationship | 2001 |
Hydrogen exchange reveals a stable and expandable core within the aspartate receptor cytoplasmic domain.
Topics: Calorimetry; Chromatography, Gel; Cytoplasm; Dimerization; Glutamic Acid; Histidine; Hot Temperature; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutation; Plasmids; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Amino Acid; Temperature; Time Factors; Tritium | 2001 |
Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase.
Topics: Amino Acids; Aspartic Acid; beta-Cyclodextrins; Binding Sites; Cyclodextrins; Dose-Response Relationship, Drug; Escherichia coli; Glucosyltransferases; Glutamic Acid; Histidine; Hydrolysis; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Protein Binding; Protein Conformation; Substrate Specificity; Water | 2001 |
The distal hinge of the reactive site loop and its proximity: a target to modulate plasminogen activator inhibitor-1 activity.
Topics: Alanine; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Arginine; Aspartic Acid; Binding Sites; DNA; Epitopes; Glutamic Acid; Histidine; Humans; Kinetics; Lysine; Mice; Models, Molecular; Molecular Sequence Data; Mutation; Plasminogen Activator Inhibitor 1; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Surface Plasmon Resonance; Swine; Time Factors | 2001 |
Crystal structure at 1.5-A resolution of Pyrus pyrifolia pistil ribonuclease responsible for gametophytic self-incompatibility.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Glutamic Acid; Histidine; Lysine; Models, Molecular; Molecular Sequence Data; Plants; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Ribonucleases; Sequence Homology, Amino Acid | 2001 |
The conserved methionine residue of the metzincins: a site-directed mutagenesis study.
Topics: Amino Acid Substitution; Binding Sites; Consensus Sequence; Conserved Sequence; Crystallization; Crystallography, X-Ray; Dickeya chrysanthemi; Enzyme Stability; Glutamic Acid; Histidine; Kinetics; Ligands; Methionine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Serine Endopeptidases; Zinc | 2001 |
Residues 137 and 153 at the N terminus of the XylS protein influence the effector profile of this transcriptional regulator and the sigma factor used by RNA polymerase to stimulate transcription from its cognate promoter.
Topics: Amino Acids; Asparagine; Aspartic Acid; Bacterial Proteins; beta-Galactosidase; DNA; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Escherichia coli; Glutamic Acid; Histidine; Mutation; Plasmids; Point Mutation; Promoter Regions, Genetic; Protein Structure, Tertiary; RNA; Trans-Activators; Transcription, Genetic | 2002 |
Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.
Topics: Adenosine; Alanine; Aspartic Acid; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Histidine; Hydrogen Bonding; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Succinate-CoA Ligases; Time Factors | 2002 |
Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29.
Topics: Animals; Blotting, Western; Brain; Calcium; Calpain; Carrier Proteins; COS Cells; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; DNA; Dose-Response Relationship, Drug; Glutamic Acid; Histidine; Humans; Ionomycin; Ionophores; Ischemia; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neurons; Plasmids; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Rats; Sequence Analysis, DNA; Time Factors; Transcription, Genetic; Transfection | 2002 |
Twists and turns of the cation-dependent mannose 6-phosphate receptor. Ligand-bound versus ligand-free receptor.
Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Cysteine; Cytoplasm; Dimerization; Endosomes; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Molecular Sequence Data; Phosphates; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, IGF Type 2; Sequence Homology, Amino Acid | 2002 |
S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B.
Topics: Amidohydrolases; Aspartic Acid; Binding Sites; Cathepsin B; Exopeptidases; Glutamic Acid; Histidine; Humans; Ions; Kinetics; Lysosomes; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Substrate Specificity; Tolbutamide | 2002 |
Enthalpic homogeneous pair interaction coefficients of L-alpha-amino acids as a hydrophobicity parameter of amino acid side chains.
Topics: Amino Acids; Arginine; Asparagine; Calorimetry; Cysteine; Glutamic Acid; Glutamine; Histidine; Solutions; Stereoisomerism; Thermodynamics; Tryptophan; Water | 2002 |
Structure-function analysis of human triacylglycerol hydrolase by site-directed mutagenesis: identification of the catalytic triad and a glycosylation site.
Topics: Animals; Catalytic Domain; Cells, Cultured; Escherichia coli; Glutamic Acid; Glycosylation; Histidine; Humans; Insecta; Lipase; Models, Molecular; Mutagenesis, Site-Directed; Recombinant Proteins; Serine; Structure-Activity Relationship | 2002 |
Construction of a catalytically inactive cholesterol oxidase mutant: investigation of the interplay between active site-residues glutamate 361 and histidine 447.
Topics: Binding Sites; Caveolae; Cell Membrane; Cholesterol Oxidase; Circular Dichroism; Glutamic Acid; Histidine; Humans; In Vitro Techniques; Lipid Bilayers; Models, Molecular; Mutation; Protein Binding; Spectrophotometry, Ultraviolet | 2002 |
Hsc62, Hsc56, and GrpE, the third Hsp70 chaperone system of Escherichia coli.
Topics: Adenosine Triphosphatases; Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Cloning, Molecular; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Histidine; HSP70 Heat-Shock Proteins; Molecular Chaperones; Molecular Sequence Data; Mutation; Plasmids; Proline; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Time Factors | 2002 |
Molecular determinants of intracellular pH modulation of human Kv1.4 N-type inactivation.
Topics: Amino Acid Substitution; Arginine; Electrophysiology; Gene Deletion; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Kv1.4 Potassium Channel; Potassium Channels; Potassium Channels, Voltage-Gated; Time Factors | 2002 |
Mutational, kinetic, and NMR studies of the mechanism of E. coli GDP-mannose mannosyl hydrolase, an unusual Nudix enzyme.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Catalysis; DNA Mutational Analysis; Escherichia coli Proteins; Glutamic Acid; Glutamine; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nudix Hydrolases; Osmolar Concentration; Protons; Pyrophosphatases; Temperature | 2002 |
Halide-stabilizing residues of haloalkane dehalogenases studied by quantum mechanic calculations and site-directed mutagenesis.
Topics: Amino Acids; Anions; Asparagine; Glutamic Acid; Halogens; Histidine; Hydrolases; Isoleucine; Leucine; Mathematical Computing; Models, Chemical; Mutagenesis, Site-Directed; Phenylalanine; Proline; Quantum Theory; Static Electricity; Tryptophan; Valine | 2002 |
Directed evolution experiments reveal mutations at cycloartenol synthase residue His477 that dramatically alter catalysis.
Topics: Amino Acid Sequence; Aspartic Acid; Catalysis; Conserved Sequence; Directed Molecular Evolution; Glutamic Acid; Histidine; Intramolecular Transferases; Lanosterol; Molecular Structure; Mutation; Structure-Activity Relationship; Yeasts | 2002 |
Influence of the protein environment on the properties of a tyrosyl radical in reaction centers from Rhodobacter sphaeroides.
Topics: Arginine; Dimerization; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Light-Harvesting Protein Complexes; Models, Molecular; Mutagenesis, Site-Directed; Photosynthetic Reaction Center Complex Proteins; Rhodobacter sphaeroides; Spectrophotometry; Spectroscopy, Near-Infrared; Tyrosine | 2002 |
Chemical rescue of proton transfer in catalysis by carbonic anhydrases in the beta- and gamma-class.
Topics: Alanine; Arabidopsis Proteins; Archaeal Proteins; Asparagine; Carbonic Anhydrase II; Carbonic Anhydrases; Catalysis; Electron Transport; Glutamic Acid; Histidine; Humans; Isoenzymes; Methanosarcina; Mutagenesis, Site-Directed; Protons | 2002 |
Isolation of a negative control mutant of the nitrogen assimilation control protein, NAC, in Klebsiella aerogenes.
Topics: Bacterial Proteins; DNA-Binding Proteins; Enterobacter aerogenes; Enzyme Repression; Gene Expression Regulation, Bacterial; Glutamic Acid; Histidine; Mutagenesis, Site-Directed; Mutation; Promoter Regions, Genetic; Trans-Activators; Transcription Factors; Transcription, Genetic; Urea | 2003 |
Amino acid substitutions at position 43 of NaeI endonuclease. Evidence for changes in NaeI structure.
Topics: Alanine; Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Asparagine; Chromatography; Circular Dichroism; Crystallography, X-Ray; Deoxyribonucleases, Type II Site-Specific; Dimerization; DNA Ligases; DNA Restriction Enzymes; DNA Topoisomerases; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Histidine; Leucine; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Proteins; Sequence Homology, Amino Acid; Temperature; Ultraviolet Rays | 2003 |
Substrate recognition and molecular mechanism of fatty acid hydroxylation by cytochrome P450 from Bacillus subtilis. Crystallographic, spectroscopic, and mutational studies.
Topics: Arginine; Bacillus subtilis; Binding Sites; Crystallography, X-Ray; Cysteine; Cytochrome P-450 Enzyme System; Escherichia coli; Fatty Acids; Glutamic Acid; Histidine; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Oxygen; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Substrate Specificity | 2003 |
Crystal structure of triosephosphate isomerase complexed with 2-phosphoglycolate at 0.83-A resolution.
Topics: Animals; Anisotropy; Binding Sites; Crystallography, X-Ray; Dimerization; Glutamic Acid; Glycolates; Histidine; Hydrogen Bonding; Leishmania mexicana; Models, Chemical; Models, Molecular; Proline; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protons; Triose-Phosphate Isomerase | 2003 |
Changes in stability upon charge reversal and neutralization substitution in staphylococcal nuclease are dominated by favorable electrostatic effects.
Topics: Amino Acid Substitution; Aspartic Acid; Enzyme Stability; Glutamic Acid; Glutamine; Guanidine; Histidine; Hydrogen-Ion Concentration; Lysine; Micrococcal Nuclease; Models, Chemical; Normal Distribution; Poisson Distribution; Protein Denaturation; Protein Folding; Static Electricity; Surface Properties; Thermodynamics | 2003 |
Examining the role of glutamic acid 183 in chloroperoxidase catalysis.
Topics: Aspergillus niger; Catalase; Catalysis; Chloride Peroxidase; Chlorine; Chromatography, Ion Exchange; Circular Dichroism; Crystallography, X-Ray; Electrophoresis, Polyacrylamide Gel; Fungi; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Immunoblotting; Isoelectric Focusing; Mutation; Oxidoreductases; Plasmids | 2003 |
Pyruvate carboxylase is an essential protein in the assembly of yeast peroxisomal oligomeric alcohol oxidase.
Topics: Aspartic Acid; Blotting, Western; Cytosol; Glutamic Acid; Histidine; Immunohistochemistry; Microscopy, Electron; Mutation; Peroxisomes; Pichia; Plasmids; Protein Binding; Pyruvate Carboxylase; Spectrometry, Fluorescence; Time Factors | 2003 |
Characterization of metal ligand mutants of tyrosine hydroxylase: insights into the plasticity of a 2-histidine-1-carboxylate triad.
Topics: Amino Acid Motifs; Animals; Binding Sites; Carboxylic Acids; Catalysis; Dopamine; Glutamic Acid; Glutamine; Histidine; Iron; Kinetics; Ligands; Mutagenesis, Site-Directed; Protein Binding; Rats; Tyrosine 3-Monooxygenase | 2003 |
NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Aspartic Acid; Binding Sites; Genetic Variation; Glutamic Acid; Glycine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Lysine; Models, Chemical; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Ovomucin; Protein Conformation; Protein Structure, Tertiary; Serine Proteinase Inhibitors; Thermodynamics; Threonine; Titrimetry; Turkeys | 2003 |
Modeling zinc in biomolecules with the self consistent charge-density functional tight binding (SCC-DFTB) method: applications to structural and energetic analysis.
Topics: Alcohol Dehydrogenase; Algorithms; Aminopeptidases; Aspartic Acid; Bacterial Proteins; Binding Sites; Carbonic Anhydrases; Cysteine; Glutamic Acid; Histidine; Liver; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Water; Zinc | 2003 |
A model of repression: CTD analogs and PIE-1 inhibit transcriptional elongation by P-TEFb.
Topics: Alanine; Animals; Binding Sites; Binding, Competitive; Blotting, Western; Caenorhabditis elegans; Caenorhabditis elegans Proteins; COS Cells; Cyclin-Dependent Kinase 9; Cyclin-Dependent Kinases; Glutamic Acid; HeLa Cells; Histidine; Humans; Models, Genetic; Mutation; Nuclear Proteins; Peptides; Phosphorylation; Plasmids; Positive Transcriptional Elongation Factor B; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Ribonucleases; RNA Polymerase II; Serine; Transcription, Genetic; Transcriptional Activation; Transfection | 2003 |
Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation.
Topics: Acetic Acid; Alanine; Animals; Astrocytes; beta-Alanine; Biological Transport; Carbon Isotopes; Cell Compartmentation; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Humans; In Vitro Techniques; Lactic Acid; Magnetic Resonance Spectroscopy; Neuroblastoma; Rats | 2003 |
Galactose mutarotase: pH dependence of enzymatic mutarotation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Carbohydrate Epimerases; Escherichia coli; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Sequence Alignment | 2003 |
The mechanism of Mycobacterium tuberculosis alkylhydroperoxidase AhpD as defined by mutagenesis, crystallography, and kinetics.
Topics: Antioxidants; Bacterial Proteins; Binding Sites; Catalysis; Catalytic Domain; Cell Division; Crystallography, X-Ray; Cysteine; Dimerization; Disulfides; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Mycobacterium tuberculosis; Oxygen; Peroxidases; Peroxiredoxins; Protein Conformation; Protons; Thioredoxins; Ultraviolet Rays | 2003 |
Glutamic acid residues as metal ligands in the active site of Escherichia coli alkaline phosphatase.
Topics: Alkaline Phosphatase; Amino Acid Substitution; Aspartic Acid; Binding Sites; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Ligands; Magnesium; Metals; Mutagenesis, Site-Directed; Phosphorylation; Structure-Activity Relationship; Zinc | 2003 |
Electrostatic interactions in leucine zippers: thermodynamic analysis of the contributions of Glu and His residues and the effect of mutating salt bridges.
Topics: Amino Acid Sequence; Arginine; DNA-Binding Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Leucine Zippers; Lysine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Norleucine; Peptides; Protein Folding; Protein Kinases; Saccharomyces cerevisiae Proteins; Salts; Static Electricity; Thermodynamics | 2003 |
Functional consequences of alterations to Ile279, Ile283, Glu284, His285, Phe286, and His288 in the NH2-terminal part of transmembrane helix M3 of the Na+,K(+)-ATPase.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Catalysis; Cell Survival; COS Cells; Crystallography, X-Ray; DNA, Complementary; Enzyme Inhibitors; Glutamic Acid; Histidine; Isoleucine; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Oligomycins; Ouabain; Phenylalanine; Phosphorylation; Potassium; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Sodium; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Time Factors; Vanadates | 2003 |
Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family.
Topics: Amidohydrolases; Amino Acid Sequence; Binding Sites; Catalysis; Crystallization; Crystallography, X-Ray; Dimerization; Enzyme Stability; Glutamic Acid; Histidine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Protein Structure, Secondary; Sequence Alignment; Structure-Activity Relationship; Thermodynamics; Zinc | 2003 |
Computational study on mechanistic details of the aminoethanol rearrangement catalyzed by the vitamin B12-dependent ethanolamine ammonia lyase: His and Asp/Glu acting simultaneously as catalytic auxiliaries.
Topics: Aspartic Acid; Binding Sites; Catalysis; Computational Biology; Ethanolamine Ammonia-Lyase; Ethanolamines; Glutamic Acid; Histidine; Indicators and Reagents; Molecular Conformation; Thermodynamics; Vitamin B 12 | 2003 |
The conversion of l-histidine to glutamic acid by liver enzymes.
Topics: Glutamates; Glutamic Acid; Histidine; Liver; Transferases | 1952 |
Occurrence of two different glutamate dehydrogenase activities in the halophilic bacterium Salinibacter ruber.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Bacterial Proteins; Bacteroidetes; Enzyme Activation; Enzyme Stability; Glutamate Dehydrogenase; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ketoglutaric Acids; Leucine; NAD; NADP; Phenylalanine; Potassium Chloride; Sodium Chloride; Substrate Specificity | 2003 |
The formation of urocanic acid and glutamic acid in the fermentation of histidine by Clostridium tetanomorphum.
Topics: Clostridium; Clostridium tetanomorphum; Fermentation; Glutamates; Glutamic Acid; Histidine; Imidazoles; Urocanic Acid | 1954 |
Isolation of N-formyl-L-glutamic acid as an intermediate in the enzymatic degradation of L-histidine.
Topics: Glutamates; Glutamic Acid; Histidine | 1954 |
Enzymatic conversion of alpha formamidinoglutaric acid to glutamic acid by rat liver.
Topics: Biochemical Phenomena; Glutamates; Glutamic Acid; Histidine; Liver | 1955 |
Gamma irradiation of polypeptides: transformation of amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Methionine; Peptides; Phenylalanine; Proline; Radiation Effects; Tyrosine | 1963 |
Urinary excretion of urocanic acid and formimino-glutamic acid.
Topics: Anemia; Anemia, Macrocytic; Avitaminosis; Glutamates; Glutamic Acid; Histidine; Humans; Imidazoles; Urocanic Acid | 1962 |
Nutrition of five Bacteroides strains.
Topics: Amino Acids; Arginine; Bacteroides; Culture Media; Fusobacterium; Glucose; Glutamic Acid; Histidine; Lysine; Phenylalanine; Purines; Tyrosine; Vitamins | 1962 |
EFFECT OF CATIONS UPON HYDROPHOBICITY OF YEASTS GROWN IN AMINO ACID MEDIA.
Topics: Amino Acids; Ammonium Compounds; Cations; Chlorides; Culture Media; Glutamic Acid; Histidine; Hydrophobic and Hydrophilic Interactions; Lysine; Nitrogen; Phenylalanine; Proline; Quaternary Ammonium Compounds; Research; Tryptophan; Tyrosine; Valine; Yeasts | 1963 |
ABSORPTION SPECTRA OF HEMATIN COMPLEXES WITH POLYHISTIDINE AND COPOLY-(HISTIDINE, GLUTAMIC ACID).
Topics: Animals; Cytochromes; Glutamates; Glutamic Acid; Heme; Hemin; Histidine; Horses; Methemoglobin; Peptides; Research; Spectrophotometry | 1963 |
FORMIMINO-GLUTAMIC ACID EXCRETION IN ANAEMIA OF PREGNANCY.
Topics: Anemia; Anemia, Macrocytic; Biopsy; Blood Chemical Analysis; Bone Marrow Examination; Erythropoiesis; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Glutamic Acid; Hemoglobins; Histidine; Lactobacillus; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Urine; Vitamin B 12 | 1964 |
THE EXCRETION OF UROCANIC ACID AND FORMIMINO GLUTAMIC ACID IN MEGALOBLASTOSIS ACCOMPANYING KWASHIORKOR.
Topics: Anemia; Anemia, Macrocytic; Avitaminosis; Blood Cell Count; Bone Marrow Examination; Child; FIGLU Test; Folic Acid; Folic Acid Deficiency; Glutamates; Glutamic Acid; Histidine; Humans; Imidazoles; Kwashiorkor; Metabolism; Urine; Urocanic Acid; Vitamin B 12 | 1965 |
POLY-L-HISTIDINE AND THE COPOLYMER OF L-HISTIDINE WITH L-GLUTAMIC ACID. THEIR SYNTHESIS AND CATALYTIC ACTIVITY ON THE HYDROLYSIS OF P-NITROPHENYL ACETATE.
Topics: Chemical Phenomena; Chemistry; Glutamates; Glutamic Acid; Histidine; Hydrolysis; Nitrophenols; Peptides; Polymers; Research | 1965 |
Amino acid requirements for maintenance in the adult rooster. II. The requirements for glutamic acid, histidine, lysine and arginine.
Topics: Animals; Arginine; Chickens; Diet; Glutamates; Glutamic Acid; Histidine; Lysine; Male; Nutrition Assessment; Nutritional Status | 1959 |
The crystal structure of Escherichia coli heat shock protein YedU reveals three potential catalytic active sites.
Topics: Amino Acid Motifs; Amino Acid Sequence; Aspartic Acid; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Cysteine; Dimerization; Electronic Data Processing; Escherichia coli Proteins; Glutamic Acid; Heat-Shock Proteins; Histidine; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Chaperones; Molecular Sequence Data; Protein Structure, Quaternary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Structural Homology, Protein; Zinc | 2003 |
Contribution of active site residues to the activity and thermal stability of ribonuclease Sa.
Topics: Arginine; Calorimetry, Differential Scanning; Catalysis; Catalytic Domain; Dinucleoside Phosphates; Enzyme Stability; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mutagenesis, Site-Directed; Poly I; Recombinant Proteins; Ribonucleases; Substrate Specificity; Thermodynamics | 2003 |
Dissecting structural and electrostatic interactions of charged groups in alpha-sarcin. An NMR study of some mutants involving the catalytic residues.
Topics: Amino Acid Substitution; Aspergillus; Binding Sites; Catalytic Domain; Endoribonucleases; Fungal Proteins; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Models, Chemical; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protons; Static Electricity | 2003 |
Role of His-16 in turnover of T4 pyrimidine dimer glycosylase.
Topics: Alanine; Aspartic Acid; Cell Survival; Cysteine; Dimerization; DNA; DNA Glycosylases; DNA Repair; Escherichia coli; Glutamic Acid; Histidine; Kinetics; Lysine; Models, Biological; Mutagenesis, Site-Directed; Mutation; Oligonucleotides; Phenotype; Plasmids; Serine; Time Factors; Ultraviolet Rays | 2004 |
Crystal structure of the E2 transactivation domain of human papillomavirus type 11 bound to a protein interaction inhibitor.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Amino Acids; Binding Sites; Calorimetry; Circular Dichroism; Crystallography, X-Ray; DNA Mutational Analysis; Dose-Response Relationship, Drug; Glutamic Acid; Histidine; Leucine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Transcriptional Activation; Tyrosine; Ultracentrifugation; Viral Proteins | 2004 |
Contribution of molecular modeling and site-directed mutagenesis to the identification of a new residue, glutamate 215, involved in the exopeptidase specificity of aminopeptidase A.
Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Enzyme Activation; Exopeptidases; Glutamates; Glutamic Acid; Glutamyl Aminopeptidase; Histidine; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Organophosphonates; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Substrate Specificity; Transfection | 2003 |
Tyrosine-728 and glutamic acid-735 are essential for the metalloproteolytic activity of the lethal factor of Bacillus anthracis.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Carrier Proteins; Catalysis; Circular Dichroism; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; Glutathione Transferase; Histidine; Macrophages; Mitogen-Activated Protein Kinase Kinases; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Rats; Rats, Inbred F344; Recombinant Proteins; Spectrophotometry; Time Factors; Tyrosine; Urea; Zinc | 2004 |
Mechanism of proton gating of a urea channel.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Bacterial Proteins; Biological Transport; Cell Membrane; Glutamic Acid; Helicobacter hepaticus; Helicobacter pylori; Histidine; Hydrogen-Ion Concentration; Membrane Transport Proteins; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Structure, Tertiary; Protons; RNA; Sequence Homology, Amino Acid; Streptococcus; Urea; Urease; Xenopus; Xenopus laevis | 2004 |
Molecular mechanism of the enterococcal aminoglycoside 6'-N-acetyltransferase': role of GNAT-conserved residues in the chemistry of antibiotic inactivation.
Topics: Acetyltransferases; Amino Acid Sequence; Amino Acid Substitution; Aminoglycosides; Anti-Bacterial Agents; Conserved Sequence; Drug Resistance, Bacterial; Enterococcus faecium; Enzyme Activation; Glutamic Acid; Histidine; Histone Acetyltransferases; Hydrogen-Ion Concentration; Kinetics; Leucine; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed; Tyrosine | 2004 |
betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation.
Topics: Amino Acid Substitution; Animals; Cell Line; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Glycine; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Histidine; Humans; Leucine; Oocytes; Point Mutation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Tertiary; Recombinant Fusion Proteins; Xenopus | 2004 |
JAMM: a metalloprotease-like zinc site in the proteasome and signalosome.
Topics: Amino Acid Motifs; Animals; Archaea; Archaeoglobus fulgidus; Aspartic Acid; Binding Sites; DNA-Binding Proteins; Glutamic Acid; Histidine; Humans; Hydrogen Bonding; Metalloproteases; Molecular Sequence Data; Mutagenesis; NEDD8 Protein; Open Reading Frames; Proteasome Endopeptidase Complex; Protein Conformation; Protein Folding; Signal Transduction; Thermolysin; Transcription Factors; Ubiquitins; Zinc | 2004 |
Identification of two novel mutations in the Cu/Zn superoxide dismutase gene with familial amyotrophic lateral sclerosis: mass spectrometric and genomic analyses.
Topics: Age of Onset; Amyotrophic Lateral Sclerosis; Aspartic Acid; Chromatography, Liquid; DNA Mutational Analysis; Erythrocytes; Exons; Family Health; Female; Glutamic Acid; Glycine; Histidine; Humans; Male; Molecular Biology; Molecular Sequence Data; Mutation; Precipitin Tests; Spectrometry, Mass, Electrospray Ionization; Superoxide Dismutase | 2004 |
The enzymatic conversion of histidine to glutamic acid.
Topics: Glutamates; Glutamic Acid; Histidine; Pseudomonas | 1952 |
Binding ability of a HHP-tagged protein towards Ni2+ studied by paramagnetic NMR relaxation: the possibility of obtaining long-range structure information.
Topics: Aspartic Acid; Dimerization; Escherichia coli; Glutamic Acid; Histidine; Models, Theoretical; Nickel; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Protons; Recombinant Fusion Proteins; Thioredoxins | 2004 |
Residues in the hydrophilic face of putative helix 8 of oxytocin receptor are important for receptor function.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cattle; COS Cells; Glutamic Acid; Histidine; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Sequence Data; Oxytocin; Protein Binding; Protein Structure, Secondary; Rats; Receptors, Oxytocin; Receptors, Vasopressin; Signal Transduction; Transfection | 2004 |
Long-range nature of the interactions between titratable groups in Bacillus agaradhaerens family 11 xylanase: pH titration of B. agaradhaerens xylanase.
Topics: Aspartic Acid; Bacillus; Bacterial Proteins; Carboxylic Acids; Endo-1,4-beta Xylanases; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Imidazoles; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protons; Recombinant Proteins; Static Electricity; Titrimetry | 2004 |
His23beta and Glu455beta of the Pseudomonas sp. 130 glutaryl-7-amino cephalosporanic acid acylase are crucially important for efficient autoproteolysis and enzymatic catalysis.
Topics: Amino Acid Sequence; Cephalosporins; Conserved Sequence; Glutamic Acid; Histidine; Molecular Sequence Data; Penicillin Amidase; Protein Processing, Post-Translational; Pseudomonas | 2004 |
The distinct functional properties of the nucleotide-binding domain of ATP7B, the human copper-transporting ATPase: analysis of the Wilson disease mutations E1064A, H1069Q, R1151H, and C1104F.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Arginine; Calorimetry; Cation Transport Proteins; Circular Dichroism; Copper-Transporting ATPases; Cysteine; Glutamic Acid; Histidine; Humans; Kinetics; Magnesium; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nucleotides; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Temperature | 2004 |
Biochemistry. De novo design of an enzyme.
Topics: Algorithms; Amino Acid Substitution; Binding Sites; Catalysis; Computational Biology; Computer Simulation; Directed Molecular Evolution; Escherichia coli Proteins; Glutamic Acid; Glyceraldehyde 3-Phosphate; Histidine; Hydrogen Bonding; Lysine; Models, Molecular; Periplasmic Binding Proteins; Protein Conformation; Protein Engineering; Triose-Phosphate Isomerase | 2004 |
Heme structures of five variants of hemoglobin M probed by resonance Raman spectroscopy.
Topics: Carbon; Glutamic Acid; Heme; Hemoglobin M; Hemoglobins; Hemoglobins, Abnormal; Histidine; Ions; Models, Chemical; Mutation; Oxygen; Spectrum Analysis, Raman; Tyrosine | 2004 |
Chemotactic response of Helicobacter pylori to human plasma and bile.
Topics: Adaptation, Physiological; Adult; Amino Acids; Arginine; Aspartic Acid; Bile; Bile Acids and Salts; Chemotactic Factors; Chemotaxis; Glutamic Acid; Glycine; Helicobacter pylori; Histidine; Humans; In Vitro Techniques; Male; Plasma; Taurocholic Acid; Taurodeoxycholic Acid; Urea | 2004 |
Functional characterization of the yeast Ppz1 phosphatase inhibitory subunit Hal3: a mutagenesis study.
Topics: Amino Acid Motifs; Amino Acid Sequence; Catalysis; Cell Cycle Proteins; Dose-Response Relationship, Drug; Escherichia coli; Fungal Proteins; Genetic Complementation Test; Glutamic Acid; Histidine; Models, Genetic; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phenotype; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Plasmids; Polymerase Chain Reaction; Protein Binding; Protein Phosphatase 1; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Valine | 2004 |
Ingestion of histidine and the glutamic acid blood level in rats.
Topics: Animals; Eating; Enzymes; Glutamic Acid; Histidine; Rats | 1950 |
Negatively charged residues and hydrogen bonds tune the ligand histidine pKa values of Rieske iron-sulfur proteins.
Topics: Animals; Aspartic Acid; Burkholderia; Cattle; Computer Simulation; Electron Transport Complex III; Ferredoxins; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Rhodobacter sphaeroides; Static Electricity; Thermodynamics; Titrimetry | 2004 |
The Y42H mutation in medium-chain acyl-CoA dehydrogenase, which is prevalent in babies identified by MS/MS-based newborn screening, is temperature sensitive.
Topics: Acyl-CoA Dehydrogenase; Amino Acid Substitution; Animals; Circular Dichroism; Enzyme Stability; Escherichia coli; Fibroblasts; Glutamic Acid; Histidine; Humans; Infant, Newborn; Lymphocytes; Lysine; Mitochondria, Liver; Models, Molecular; Mutagenesis, Site-Directed; Myristic Acid; Neonatal Screening; Oxidation-Reduction; Rats; Recombinant Proteins; Structure-Activity Relationship; Tyrosine | 2004 |
Role of lysine-256 in Citrobacter freundii tyrosine phenol-lyase in monovalent cation activation.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cations, Monovalent; Citrobacter freundii; Enzyme Activation; Glutamic Acid; Histidine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Potassium; Protein Binding; Pyridoxal Phosphate; Rabbits; Spectrophotometry; Tyrosine Phenol-Lyase | 2004 |
Kinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases.
Topics: Carbon; Carboxylic Acids; Catalysis; Cytosol; Electrophoresis; Genetic Complementation Test; Glucose; Glutamic Acid; Glycerol; Histidine; Hydrogen-Ion Concentration; Immunoblotting; Isocitrate Dehydrogenase; Isocitrates; Ketoglutaric Acids; Kinetics; Lactates; NAD; NADP; Phenotype; Plasmids; Protein Isoforms; Saccharomyces cerevisiae; Time Factors | 2005 |
Catalytic roles of active-site amino acid residues of coenzyme B12-dependent diol dehydratase: protonation state of histidine and pull effect of glutamate.
Topics: Binding Sites; Catalysis; Cobamides; Glutamic Acid; Histidine; Hydrogen; Kinetics; Models, Molecular; Potassium; Propanediol Dehydratase; Protein Conformation; Quantum Theory; Thermodynamics | 2004 |
Energetics of proton transfer pathways in reaction centers from Rhodobacter sphaeroides. The Glu-H173 activated mutants.
Topics: Alanine; Cysteine; Cytoplasm; Electron Transport; Electrons; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Models, Molecular; Mutation; Nitrogen; Oxidation-Reduction; Oxygen; Protons; Rhodobacter sphaeroides; Software | 2005 |
Analysis of glutamine accumulation in rat brain mitochondria in the presence of a glutamine uptake inhibitor, histidine, reveals glutamine pools with a distinct access to deamidation.
Topics: Amides; Animals; Arginine; Brain Chemistry; Cerebral Cortex; Glutamic Acid; Glutamine; Hippocampus; Histidine; Lysine; Male; Mitochondria; Rats | 2004 |
Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway.
Topics: Alanine; Amidohydrolases; Asparagine; Aspartic Acid; Bacterial Proteins; Glutamic Acid; Gram-Negative Bacteria; Histidine; Hydrogen-Ion Concentration; Kinetics; Lipid A; Lysine; Mutagenesis, Site-Directed; Substrate Specificity; Zinc | 2005 |
Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging.
Topics: Animals; Binding Sites; Butyrylcholinesterase; Catalysis; Cholinesterase Inhibitors; Crystallization; Crystallography, X-Ray; Echothiophate Iodide; Glutamic Acid; Glycerol; Histidine; Humans; Hydrolysis; Organophosphorus Compounds; Organothiophosphates; Peptide Fragments; Torpedo; Water | 2005 |
Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: enhancing the promiscuous D-arabino-hex-3-ulose 6-phosphate synthase reaction catalyzed by 3-keto-L-gulonate 6-phosphate decarboxylase.
Topics: Alanine; Aldehyde-Lyases; Aldehydes; Amino Acid Substitution; Arginine; Aspartic Acid; Carboxy-Lyases; Catalysis; Decarboxylation; Enzyme Stability; Escherichia coli Proteins; Evolution, Molecular; Formaldehyde; Glutamic Acid; Histidine; Ketoses; Methylomonas; Orotidine-5'-Phosphate Decarboxylase; Ribulosephosphates; Stereoisomerism; Threonine; Valine | 2005 |
Extracellular acid block and acid-enhanced inactivation of the Ca2+-activated cation channel TRPM5 involve residues in the S3-S4 and S5-S6 extracellular domains.
Topics: Amino Acid Sequence; Animals; Calcium; Cell Line; Cell Membrane; Electric Conductivity; Extracellular Space; Gene Expression; Glutamic Acid; Green Fluorescent Proteins; Histidine; Humans; Hydrogen-Ion Concentration; Intracellular Space; Membrane Proteins; Mice; Molecular Sequence Data; Mutagenesis; Recombinant Fusion Proteins; Sequence Alignment; Structure-Activity Relationship; Taste; Transfection; TRPM Cation Channels | 2005 |
The conserved histidine 295 does not contribute to proton cotransport by the glutamate transporter EAAC1.
Topics: Amino Acid Substitution; Amino Acid Transport System X-AG; Animals; Biological Transport, Active; Cell Line; Conserved Sequence; Cysteine; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Chemical; Patch-Clamp Techniques; Protons; Rats; Symporters; Transfection | 2005 |
Molecular mechanism for stabilizing a short helical peptide studied by generalized-ensemble simulations with explicit solvent.
Topics: Algorithms; Arginine; Biophysics; C-Peptide; Computer Simulation; Crystallography, X-Ray; Glutamic Acid; Histidine; Models, Molecular; Models, Statistical; Peptides; Phenylalanine; Principal Component Analysis; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Temperature; Thermodynamics; Time Factors; Water; X-Rays | 2005 |
Hinge residue Ile260 of DNA polymerase beta is important for enzyme activity and fidelity.
Topics: Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; DNA Polymerase beta; Enzyme Activation; Enzyme Stability; Escherichia coli Proteins; Genetic Complementation Test; Genetic Variation; Glutamic Acid; Glutamine; Histidine; Isoleucine; Lysine; Peptide Fragments; Phenotype; Protein Folding; Protein Structure, Tertiary; Rats; Substrate Specificity | 2005 |
Functional characterization of XendoU, the endoribonuclease involved in small nucleolar RNA biosynthesis.
Topics: Amino Acid Sequence; Animals; Catalysis; Catalytic Domain; Cloning, Molecular; DNA Primers; Endoribonucleases; Glutamic Acid; Histidine; Introns; Lysine; Manganese; Molecular Sequence Data; Mutation; Oligopeptides; Phylogeny; Plasmids; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA, Small Nuclear; Sequence Homology, Amino Acid; Substrate Specificity; Transcription, Genetic; Xenopus; Xenopus laevis; Xenopus Proteins | 2005 |
Site-directed mutagenesis of active site residues of phosphite dehydrogenase.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Binding Sites; Cysteine; Deuterium Exchange Measurement; Diethyl Pyrocarbonate; Glutamic Acid; Glutamine; Histidine; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; NADH, NADPH Oxidoreductases; Phosphites; Sequence Alignment | 2005 |
H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; ATP-Binding Cassette Transporters; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Glutamine; Hemolysin Proteins; Histidine; Hydrogen Bonding; Hydrolysis; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Structure-Activity Relationship | 2005 |
Staphylococcus aureus aminopeptidase S is a founding member of a new peptidase clan.
Topics: Aminopeptidases; Aspartic Acid; Binding Sites; Chromatography, Gel; Chromatography, Thin Layer; Cloning, Molecular; Cobalt; Crystallography, X-Ray; Dimerization; Glutamic Acid; Histidine; Ions; Ligands; Peptide Hydrolases; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrophotometry, Atomic; Staphylococcus aureus; Temperature; Ultracentrifugation; Zinc | 2005 |
Expression and characterization of the carboxyl esterase Rv3487c from Mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Carboxylesterase; Catalytic Domain; Chromatography, Affinity; Cloning, Molecular; Detergents; Enteropeptidase; Enzyme Stability; Escherichia coli; Gene Expression; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Protein Structure, Tertiary; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Serine; Temperature; Thioredoxins | 2005 |
Key role of conserved histidines in recombinant mouse beta-carotene 15,15'-monooxygenase-1 activity.
Topics: Alanine; Amino Acid Sequence; Animals; beta Carotene; beta-Carotene 15,15'-Monooxygenase; Catalysis; Chromatography; Chromatography, High Pressure Liquid; Conserved Sequence; Crystallography, X-Ray; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Glutamic Acid; Histidine; Humans; Iron; Kinetics; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxygenases; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Vitamin A | 2005 |
Redox-induced protein structural changes in cytochrome bo revealed by Fourier transform infrared spectroscopy and [13C]Tyr labeling.
Topics: Animals; Biochemistry; Cattle; Copper; Cytochromes; Electron Transport Complex IV; Escherichia coli; Glutamic Acid; Histidine; Hydrogen; Hydrogen-Ion Concentration; Ligands; Light; Models, Chemical; Models, Molecular; Oxidation-Reduction; Oxygen; Potassium; Protein Conformation; Protein Structure, Secondary; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2005 |
Did protein kinase regulatory mechanisms evolve through elaboration of a simple structural component?
Topics: Adenosine Diphosphate; Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Databases, Protein; Evolution, Molecular; Glutamic Acid; Histidine; Humans; Models, Genetic; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Monte Carlo Method; Protein Conformation; Protein Kinases; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tryptophan; Tyrosine; Water | 2005 |
Apparent pKa shifts of titratable residues at high denaturant concentration and the impact on protein stability.
Topics: Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Glutamic Acid; Guanidine; Histidine; Hydrogen-Ion Concentration; Lysine; Magnetic Resonance Spectroscopy; Protein Folding; Proteins; Sensitivity and Specificity; Titrimetry; Urea | 2005 |
Differential effects of the Zn-His-Bkb vs Zn-His-[Asp/Glu] triad on Zn-core stability and reactivity.
Topics: Aspartic Acid; Catalytic Domain; Electron Transport; Enzymes; Glutamic Acid; Histidine; Humans; Ligands; Metalloproteins; Protein Conformation; Zinc | 2005 |
Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.
Topics: Aldehydes; Anhydrides; Binding Sites; Carbapenems; Carbon-Carbon Lyases; Catalysis; Chromatography, Liquid; Crystallography, X-Ray; Enoyl-CoA Hydratase; Escherichia coli; Esters; Glutamates; Glutamic Acid; Histidine; Hydrogen Bonding; Mass Spectrometry; Models, Chemical; Models, Molecular; Mutagenesis; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Selenomethionine; Substrate Specificity; Thiolester Hydrolases; Trypsin | 2005 |
Effects of carnosine on amygdaloid-kindled seizures in Sprague-Dawley rats.
Topics: Amygdala; Animals; Anticonvulsants; Carnosine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Glutamic Acid; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Injections, Intraventricular; Kindling, Neurologic; Male; Methylhistidines; Rats; Rats, Sprague-Dawley; Seizures | 2005 |
Cardiomyopathy in Swedish patients with the Gly53Glu and His88Arg transthyretin variants.
Topics: Adipose Tissue; Aged; Arginine; Cardiomyopathies; Chromatography, High Pressure Liquid; Colon; DNA Mutational Analysis; Female; Genetic Variation; Glutamic Acid; Glycine; Histidine; Humans; Male; Middle Aged; Prealbumin; Sweden | 2005 |
Identification of conserved histidines and glutamic acid as key residues for isomerohydrolase activity of RPE65, an enzyme of the visual cycle in the retinal pigment epithelium.
Topics: Carrier Proteins; Catalysis; cis-trans-Isomerases; Eye Proteins; Glutamic Acid; Histidine; Humans; Hydrolases; Models, Molecular; Mutagenesis, Site-Directed; Pigment Epithelium of Eye | 2005 |
Sequences required for the activity of PTOX (IMMUTANS), a plastid terminal oxidase: in vitro and in planta mutagenesis of iron-binding sites and a conserved sequence that corresponds to Exon 8.
Topics: Alleles; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Base Sequence; Binding Sites; Carbonates; Conserved Sequence; DNA Primers; DNA, Complementary; Exons; Gene Expression Regulation, Plant; Glutamic Acid; Histidine; Iron; Ligands; Models, Biological; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Oxygen Consumption; Phylogeny; Plastids; Plastoquinone; Protein Structure, Tertiary; Time Factors | 2005 |
Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases.
Topics: Binding Sites; Carboxylic Acids; Catalysis; Catalytic Domain; Chromatography, Gel; Cloning, Molecular; Coenzyme A; Coenzyme A-Transferases; Crystallization; Crystallography, X-Ray; Escherichia coli; Escherichia coli Proteins; Esters; Glutamic Acid; Histidine; Mass Spectrometry; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Conformation; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary | 2005 |
Mutational analysis of the ras converting enzyme reveals a requirement for glutamate and histidine residues.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; Cloning, Molecular; Computational Biology; DNA Mutational Analysis; Endopeptidases; Genes, Reporter; Glutamic Acid; Histidine; Humans; Kinetics; Ligases; Mating Factor; Membrane Proteins; Metalloendopeptidases; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Plants; Plasmids; Proprotein Convertases; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Substrate Specificity; Temperature | 2006 |
Linker chains of the gigantic hemoglobin of the earthworm Lumbricus terrestris: primary structures of linkers L2, L3, and L4 and analysis of the connectivity of the disulfide bonds in linker L1.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Base Sequence; Binding Sites; Calcium; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Dithiothreitol; DNA, Complementary; Glutamic Acid; Heme; Hemoglobins; Histidine; Humans; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Oligochaeta; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Tertiary; Receptors, LDL; RNA, Messenger; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase | 2006 |
The crucial importance of chemistry in the structure-function link: manipulating hydrogen bonding in iron-containing superoxide dismutase.
Topics: Amino Acid Substitution; Binding Sites; Crystallization; Escherichia coli; Glutamic Acid; Glycine; Histidine; Hydrogen Bonding; Iron; Kinetics; Models, Molecular; Mutation; Oxidation-Reduction; Protein Folding; Structure-Activity Relationship; Superoxide Dismutase | 2006 |
Effect of co-existing biologically relevant molecules and ions on DNA photocleavage caused by pyrene and its derivatives.
Topics: DNA Damage; DNA, Superhelical; Electrophoresis, Agar Gel; Glutamic Acid; Histidine; Iodine; Ions; Metals; Mutagenicity Tests; NAD; Photochemistry; Pyrenes; Riboflavin; Ultraviolet Rays | 2005 |
Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Catalysis; Chlorella; Conserved Sequence; Crystallography, X-Ray; Diethyl Pyrocarbonate; Enzyme Inhibitors; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Kinetics; Molecular Sequence Data; Phycodnaviridae; Sequence Alignment; Structure-Activity Relationship; Substrate Specificity; Thymidylate Synthase | 2006 |
Role of the His57-Glu214 ionic couple located in the active site of Mycobacterium tuberculosis FprA.
Topics: Amino Acid Sequence; Anaerobiosis; Binding Sites; Crystallography, X-Ray; Enzyme Stability; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Hot Temperature; Kinetics; Mycobacterium tuberculosis; NAD; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction | 2006 |
The crystal structure of Deinococcus radiodurans Dps protein (DR2263) reveals the presence of a novel metal centre in the N terminus.
Topics: Amino Acid Sequence; Aspartic Acid; Bacterial Proteins; Crystallography, X-Ray; Deinococcus; DNA-Binding Proteins; Glutamic Acid; Histidine; Iron; Ligands; Models, Molecular; Molecular Sequence Data; Sequence Alignment; Zinc | 2006 |
Identification of the zinc binding ligands and the catalytic residue in human aspartoacylase, an enzyme involved in Canavan disease.
Topics: Amidohydrolases; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Canavan Disease; Catalytic Domain; DNA, Complementary; Escherichia coli; Glutamic Acid; Histidine; Humans; In Vitro Techniques; Kinetics; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Recombinant Proteins; Sequence Homology, Amino Acid; Zinc | 2006 |
Vesicular glutamate transporter contains two independent transport machineries.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Arginine; Biological Transport; Chlorides; Glutamic Acid; Histidine; Insecta; Membrane Potentials; Molecular Sequence Data; Mutation; Phosphates; Sodium; Vesicular Glutamate Transport Protein 2 | 2006 |
Catalytic site modifications of TAP1 and TAP2 and their functional consequences.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP Binding Cassette Transporter, Subfamily B, Member 3; ATP-Binding Cassette Transporters; Baculoviridae; Binding Sites; Catalytic Domain; Cell Line, Tumor; Genetic Vectors; Glutamic Acid; Glutamine; Histidine; Humans; Nucleotides; Protein Transport | 2006 |
Molecular mechanism of the regulation of Bacillus subtilis gltAB expression by GltC.
Topics: Bacillus subtilis; Bacterial Proteins; Base Sequence; Deoxyribonuclease I; DNA Footprinting; DNA-Directed RNA Polymerases; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Glutamate Synthase; Glutamic Acid; Histidine; Ketoglutaric Acids; Models, Genetic; Molecular Sequence Data; Mutant Proteins; Oligopeptides; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Trans-Activators; Transcription, Genetic | 2007 |
Carnosine protects against NMDA-induced neurotoxicity in differentiated rat PC12 cells through carnosine-histidine-histamine pathway and H(1)/H(3) receptors.
Topics: Animals; Carnosine; Cell Differentiation; gamma-Aminobutyric Acid; Glutamic Acid; Histamine; Histidine; Methylhistidines; N-Methylaspartate; Neurons; PC12 Cells; Piperidines; Rats; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3 | 2007 |
Endogenous histamine inhibits the development of morphine-induced conditioned place preference.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesics, Opioid; Animals; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Histamine; Histidine; Hypothalamic Area, Lateral; Injections, Intraperitoneal; Male; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2007 |
Amino acid residues His183 and Glu264 in Bacillus subtilis ferrochelatase direct and facilitate the insertion of metal ion into protoporphyrin IX.
Topics: Bacillus subtilis; Binding Sites; Conserved Sequence; Crystallography, X-Ray; Ferrochelatase; Glutamic Acid; Histidine; Iron; Models, Molecular; Mutagenesis, Site-Directed; Protoporphyrins; Water | 2007 |
Ligation independent cloning vectors for expression of SUMO fusions.
Topics: Ataxin-3; Chromatography, Gel; Cloning, Molecular; Cysteine Endopeptidases; DNA, Fungal; Escherichia coli; Genes, Reporter; Genetic Vectors; Genome, Fungal; Glutamic Acid; Green Fluorescent Proteins; Histidine; Luciferases; Nerve Tissue Proteins; Nuclear Proteins; Nucleic Acid Amplification Techniques; Plasmids; Polymerase Chain Reaction; Protein Structure, Tertiary; Recombinant Fusion Proteins; Repressor Proteins; Restriction Mapping; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Small Ubiquitin-Related Modifier Proteins; Substrate Specificity | 2007 |
Functional P2X7 receptor polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in patients with Crohn's disease.
Topics: Alanine; Amino Acid Substitution; Arginine; Case-Control Studies; Crohn Disease; Female; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Histidine; Humans; Male; Polymorphism, Single Nucleotide; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Tyrosine | 2007 |
The carboxylate shift in zinc enzymes: a computational study.
Topics: Aspartic Acid; Carboxylic Acids; Catalytic Domain; Computational Biology; Crystallography, X-Ray; Cysteine; Electron Transport; Enzymes; Glutamic Acid; Histidine; Ligands; Metalloproteins; Oxygen; Protein Conformation; Zinc | 2007 |
Redox-linked protonation state changes in cytochrome bc1 identified by Poisson-Boltzmann electrostatics calculations.
Topics: Binding Sites; Crystallography, X-Ray; Cytochromes b; Electron Transport Complex III; Fungal Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Ligands; Models, Chemical; Models, Molecular; Monte Carlo Method; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Subunits; Protons; Saccharomyces cerevisiae; Spectroscopy, Fourier Transform Infrared; Static Electricity; Structure-Activity Relationship; Substrate Specificity; Ubiquinone | 2007 |
Expression and purification of active human internal His(6)-tagged L-glutamine: D-Fructose-6P amidotransferase I.
Topics: Animals; Cells, Cultured; Circular Dichroism; Cloning, Molecular; Enzyme Activation; Fructosephosphates; Glutamic Acid; Glutaminase; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Histidine; Humans; Hydrolysis; Insecta; Kinetics; Protein Structure, Tertiary; Recombinant Proteins | 2007 |
The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
Topics: Allantoin; Amino Acid Sequence; Animals; Carboxy-Lyases; Crystallography, X-Ray; DNA Mutational Analysis; Glutamic Acid; Guanine; Histidine; Ligands; Models, Chemical; Molecular Sequence Data; Protein Folding; Uric Acid; Zebrafish; Zebrafish Proteins | 2007 |
Synthesis, characterization and biological activity of Schiff base analogues of indole-3-carboxaldehyde.
Topics: Animals; Bacteria; Fungi; Glutamic Acid; Half-Life; Histidine; Humans; Indoles; Mice; Neoplasms; Rabbits; Schiff Bases; Technetium; Tissue Distribution | 2008 |
Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Dyrk Kinases; Escherichia coli; Gene Expression Regulation, Enzymologic; Glutamic Acid; Histidine; Humans; In Vitro Techniques; Kinetics; Mass Spectrometry; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Tyrosine | 2007 |
Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Binding Sites; Cell Adhesion Molecules, Neuronal; Cell Line; Cells, Cultured; Cerebral Cortex; CHO Cells; Clone Cells; Conserved Sequence; Cricetinae; Cricetulus; Crystallography, X-Ray; Disulfides; DNA Mutational Analysis; Electroporation; Extracellular Matrix Proteins; Glutamic Acid; Histidine; Humans; LDL-Receptor Related Proteins; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis; Nerve Tissue Proteins; Neurons; Peptide Fragments; Phosphorylation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Receptors, Lipoprotein; Recombinant Fusion Proteins; Reelin Protein; Serine Endopeptidases; Zinc | 2007 |
How can a single second sphere amino acid substitution cause reduction midpoint potential changes of hundreds of millivolts?
Topics: Amino Acid Substitution; Binding Sites; Circular Dichroism; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Glutamic Acid; Glutamine; Histidine; Hydrogen Bonding; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Structure-Activity Relationship; Superoxide Dismutase | 2007 |
The determination of protonation states in proteins.
Topics: Aspartic Acid; Concanavalin A; Crystallography, X-Ray; Glutamic Acid; Hirudins; Histidine; Hydrogen Bonding; Models, Molecular; Peptide Fragments; Protein Structure, Tertiary; Proteins; Protons; Thrombin | 2007 |
Proton pathways in a [NiFe]-hydrogenase: A theoretical study.
Topics: Binding Sites; Computer Simulation; Desulfovibrio gigas; Glutamic Acid; Histidine; Hydrogenase; Models, Molecular; Monte Carlo Method; Oxidation-Reduction; Protons; Static Electricity; Water | 2008 |
The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum.
Topics: Amino Acid Sequence; Animals; Cysteine; Glutamic Acid; Histidine; Ion Channel Gating; Ion Channels; Molecular Sequence Data; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Tribolium | 2007 |
Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a.
Topics: Acid Sensing Ion Channels; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Aspartic Acid; Binding Sites; Calcium; Female; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Proteins; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins; Oocytes; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Sequence Homology, Amino Acid; Sodium Channels; Structure-Activity Relationship; Xenopus laevis | 2008 |
Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2).
Topics: Amino Acid Motifs; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Computational Biology; Endoribonucleases; Escherichia coli; Fluorides; Glutamic Acid; Guanosine Diphosphate; Histidine; Lysine; Molecular Sequence Data; Mutation; Phosphines; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA, Messenger; Sequence Deletion | 2008 |
Characterization and further stabilization of designed ankyrin repeat proteins by combining molecular dynamics simulations and experiments.
Topics: Amino Acid Sequence; Ankyrin Repeat; Ankyrins; Arginine; Binding Sites; Circular Dichroism; Combinatorial Chemistry Techniques; Computer Simulation; Consensus Sequence; Escherichia coli; Glutamic Acid; Histidine; Hot Temperature; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Light; Models, Chemical; Molecular Sequence Data; Point Mutation; Protein Binding; Protein Conformation; Protein Denaturation; Protein Engineering; Protein Structure, Secondary; Protein Structure, Tertiary; Reproducibility of Results; Scattering, Radiation; Solubility; Temperature; Thermodynamics | 2008 |
Processing of N-terminal unnatural amino acids in recombinant human interferon-beta in Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Base Sequence; Binding Sites; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutamic Acid; Glycine; Histidine; Humans; Interferon Type I; Molecular Sequence Data; Protein Engineering; Recombinant Proteins; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 2008 |
Dual involvement of CbrAB and NtrBC in the regulation of histidine utilization in Pseudomonas fluorescens SBW25.
Topics: Bacterial Proteins; Base Sequence; Carbon; Gene Expression Regulation, Bacterial; Glutamic Acid; Histidine; Microarray Analysis; Molecular Sequence Data; Nitrogen; Operon; Phenotype; Pseudomonas fluorescens; Sequence Homology, Amino Acid; Transcription Initiation Site | 2008 |
Breast cancer-associated mutations in metalloprotease disintegrin ADAM12 interfere with the intracellular trafficking and processing of the protein.
Topics: ADAM Proteins; ADAM12 Protein; Animals; Aspartic Acid; Biotinylation; Blotting, Western; Breast Neoplasms; Cell Movement; Female; Fluorescent Antibody Technique; Glutamic Acid; Glycine; Histidine; Humans; Immunoprecipitation; Leucine; Membrane Proteins; Mice; Mutation; Phenylalanine | 2008 |
Glutamate-glycine and histidine-glycine co-oligopeptides: batch co-oligomerization versus pulsed addition of N-carboxyanhydrides.
Topics: Anhydrides; Glutamic Acid; Glycine; Histidine; Oligopeptides | 2008 |
DFT investigation on the mechanism of the deacetylation reaction catalyzed by LpxC.
Topics: Amidohydrolases; Binding Sites; Carbon; Catalysis; Computational Biology; Glutamic Acid; Histidine; Hydrogen Bonding; Hydroxylation; Models, Chemical; Nitrogen; Oxygen; Protons; Substrate Specificity; Thermodynamics; Threonine; Water; Zinc | 2008 |
Post-translational modification of cellular proteins during Leishmania donovani differentiation.
Topics: Animals; Asparagine; Aspartic Acid; Cell Differentiation; Chromatography, Liquid; Glutamic Acid; Glycosylation; Histidine; Humans; Leishmania donovani; Macrophages; Mass Spectrometry; Phosphorylation; Protein Processing, Post-Translational; Proteomics | 2008 |
The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function.
Topics: Cysteine; Electrophysiology; Gene Expression Regulation; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Point Mutation; Potassium Channels, Tandem Pore Domain; Protein Structure, Tertiary; Zinc | 2008 |
Molecular mechanism of pH sensing in KcsA potassium channels.
Topics: Bacterial Proteins; Biosensing Techniques; Escherichia coli Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ion Channel Gating; Models, Molecular; Mutation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Structure, Secondary; Protein Structure, Tertiary | 2008 |
A missense mutation in ALDH18A1, encoding Delta1-pyrroline-5-carboxylate synthase (P5CS), causes an autosomal recessive neurocutaneous syndrome.
Topics: Adult; Aldehyde Dehydrogenase; Amino Acid Sequence; Base Sequence; Child; Child, Preschool; Conserved Sequence; Diagnosis, Differential; Female; Fibroblasts; Genes, Recessive; Glutamic Acid; Histidine; Humans; Immunohistochemistry; Male; Molecular Sequence Data; Mutation, Missense; Neurocutaneous Syndromes; New Zealand; Ornithine-Oxo-Acid Transaminase; Pedigree; Phenotype; Proline; Sequence Homology, Amino Acid | 2008 |
Distinct transport mechanisms in yeast ammonium transport/sensor proteins of the Mep/Amt/Rh family and impact on filamentation.
Topics: Amino Acid Sequence; Biological Transport; Escherichia coli; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Multigene Family; Nitrogen; Plasmids; Quaternary Ammonium Compounds; Saccharomyces cerevisiae; Signal Transduction; Subcellular Fractions | 2008 |
Protonation and conformational dynamics of GFP mutants by two-photon excitation fluorescence correlation spectroscopy.
Topics: Computer Simulation; Glutamic Acid; Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Luminescent Agents; Mutation; Photons; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Threonine | 2008 |
Effects of various amino acids on methionine-induced hyperhomocysteinemia in rats.
Topics: Amino Acids; Animals; Arginine; Dietary Supplements; Glutamic Acid; Histidine; Homocysteine; Hyperhomocysteinemia; Methionine; Rats | 2008 |
Control of the coordination structure of organometallic palladium complexes in an apo-ferritin cage.
Topics: Apoferritins; Binding Sites; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Mutation; Organometallic Compounds; Palladium | 2008 |
Enantioselective recognitions of chiral molecular tweezers containing imidazoliums for amino acids.
Topics: Amylose; Cellulose; Glutamic Acid; Histidine; Molecular Structure; Phenylalanine; Phenylcarbamates; Pyridines; Stereoisomerism | 2009 |
Insight into the coupling mechanism of the vitamin K-dependent carboxylase: mutation of histidine 160 disrupts glutamic acid carbanion formation and efficient coupling of vitamin K epoxidation to glutamic acid carboxylation.
Topics: Anions; Carbon Dioxide; Carbon-Carbon Ligases; Glutamic Acid; Histidine; Kinetics; Mutation; Protein Structure, Tertiary; Substrate Specificity; Vitamin K | 2008 |
Association of MUTYH Gln324His and APEX1 Asp148Glu with colorectal cancer and smoking in a Japanese population.
Topics: Aged; Asian People; Aspartic Acid; Case-Control Studies; Colorectal Neoplasms; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; Female; Genetic Predisposition to Disease; Genotype; Glutamic Acid; Glutamine; Histidine; Humans; Male; Middle Aged; Polymorphism, Genetic; Smoking | 2008 |
The inhibitory effects of DL-alanine, L-glutamic acid, L-lysine, and L-histidine on the activity of intestinal, bone, and kidney phosphatases.
Topics: Alanine; Amino Acids; Bone and Bones; Dietary Proteins; Glutamic Acid; Histidine; Humans; Kidney; Lysine; Phosphoric Monoester Hydrolases | 1948 |
Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus.
Topics: Asparagine; Bacterial Proteins; Catalytic Domain; Cysteine; Endopeptidases; Glutamic Acid; Histidine; Magnetic Resonance Spectroscopy; Protein Structure, Tertiary; Staphylococcus | 2009 |
Catalysis by Glomerella cingulata cutinase requires conformational cycling between the active and inactive states of its catalytic triad.
Topics: Acetone; Amino Acid Sequence; Apoenzymes; Carboxylic Ester Hydrolases; Catalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Histidine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Phyllachorales; Protein Structure, Secondary; Sequence Alignment; Solutions | 2009 |
The role of amino acids in the long-distance transport of La and Y in the xylem sap of tomato.
Topics: Amino Acids; Aspartic Acid; Biological Transport; Chromatography, High Pressure Liquid; Glutamic Acid; Histidine; Lanthanum; Solanum lycopersicum; Tryptophan; Xylem; Yttrium | 2009 |
Metal-histidine-glutamate as a regulator of enzymatic cycles: a case study of carbonic anhydrase.
Topics: Biocatalysis; Carbonic Anhydrase II; Catalytic Domain; Computer Simulation; Glutamic Acid; Histidine; Humans; Hydrogen Bonding; Metals; Models, Molecular; Thermodynamics | 2009 |
Evaluation of the number of ionogenic groups of inulinase by acid-base titration.
Topics: Asparagine; Aspergillus; Fungal Proteins; Glutamic Acid; Glycoside Hydrolases; Histidine; Hydrogen-Ion Concentration; Lysine; Protein Denaturation; Serine; Tyrosine | 2008 |
Voltage-dependent and -independent titration of specific residues accounts for complex gating of a ClC chloride channel by extracellular protons.
Topics: Animals; Antiporters; Cell Line; Chloride Channels; Chlorides; CLC-2 Chloride Channels; Computer Simulation; Evolution, Molecular; Glutamic Acid; Guinea Pigs; Histidine; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Kinetics; Membrane Potentials; Models, Biological; Models, Molecular; Mutation; Protein Conformation; Transfection | 2009 |
A summary of the measured pK values of the ionizable groups in folded proteins.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Isoelectric Point; Nuclear Magnetic Resonance, Biomolecular; Protein Folding; Protein Structure, Tertiary; Proteins; Titrimetry | 2009 |
Crystal structure of bovine 3-hydroxyanthranilate 3,4-dioxygenase.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Cattle; Crystallization; Crystallography, X-Ray; Glutamic Acid; Histidine; Iron; Kidney; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Quinolinic Acid; Sequence Homology, Amino Acid | 2009 |
A conserved hydrogen-bond network stabilizes the structure of Beta class glutathione S-transferases.
Topics: Alanine; Amino Acid Substitution; Catalysis; Catalytic Domain; Crystallography, X-Ray; Enzyme Stability; Glutamic Acid; Glutathione Transferase; Histidine; Hydrogen Bonding; Ochrobactrum anthropi | 2009 |
Design and engineering of an O(2) transport protein.
Topics: Biological Transport; Carbon Monoxide; Carrier Proteins; Drug Design; Globins; Glutamic Acid; Heme; Histidine; Humans; Kinetics; Ligands; Nerve Tissue Proteins; Neuroglobin; Oxidation-Reduction; Oxygen; Protein Engineering; Protein Structure, Secondary; Rotation; Spectroscopy, Fourier Transform Infrared; Substrate Specificity; Water | 2009 |
It's the proton also in ClC-2.
Topics: Animals; Antiporters; Chloride Channels; Chlorides; CLC-2 Chloride Channels; Evolution, Molecular; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Kinetics; Membrane Potentials; Models, Biological; Models, Molecular; Mutation; Protein Conformation | 2009 |
Structure-activity relationships in Kluyveromyces lactis gamma-toxin, a eukaryal tRNA anticodon nuclease.
Topics: Amino Acid Sequence; Arginine; Glutamic Acid; Histidine; Killer Factors, Yeast; Kluyveromyces; Lysine; Molecular Sequence Data; Recombinant Proteins; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2009 |
Technetium-binding in labelled HYNIC-peptide conjugates: role of coordinating amino acids.
Topics: Animals; Cattle; Glutamic Acid; Glycine; Histidine; Hydrazines; Niacinamide; Peptides; Serum Albumin, Bovine; Spectrometry, Mass, Electrospray Ionization; Technetium | 2009 |
Structural adaptability of zinc binding sites: different structures in partially, fully, and heavy-metal loaded states.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Cysteine; Glutamic Acid; Histidine; Metalloproteins; Molecular Sequence Data; Molecular Structure; Zinc; Zinc Fingers | 2009 |
Role of intramembrane polar residues in the YgfO xanthine permease: HIS-31 and ASN-93 are crucial for affinity and specificity, and ASP-304 and GLU-272 are irreplaceable.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Escherichia coli K12; Escherichia coli Proteins; Evolution, Molecular; Glutamic Acid; Histidine; Membrane Transport Proteins; Models, Biological; Mutation, Missense; Nucleobase Transport Proteins; Protein Structure, Secondary; Substrate Specificity; Xanthine | 2009 |
Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: reactivation involving flipping of the His447 ring to form a reactive Glu334-His447-oxime triad.
Topics: Acetylcholinesterase; Animals; Catalytic Domain; Crystallization; Crystallography, X-Ray; Glutamic Acid; Histidine; Humans; Mice; Models, Chemical; Models, Molecular; Organophosphorus Compounds; Oximes; Protein Binding | 2010 |
Mutation of His465 alters the pH-dependent spectroscopic properties of Escherichia coli glutamate decarboxylase and broadens the range of its activity toward more alkaline pH.
Topics: Amines; Binding Sites; Circular Dichroism; Computational Biology; Escherichia coli; Glutamate Decarboxylase; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Mutation; Protein Conformation | 2009 |
Kinetic and CD/MCD spectroscopic studies of the atypical, three-His-ligated, non-heme Fe2+ center in diketone dioxygenase: the role of hydrophilic outer shell residues in catalysis.
Topics: Acinetobacter; Catalysis; Circular Dichroism; Cysteine Dioxygenase; Dioxygenases; Enzyme Stability; Ferrous Compounds; Glutamic Acid; Glutamine; Hemeproteins; Histidine; Kinetics; Ligands; Mutagenesis, Site-Directed; Protein Binding; Water | 2010 |
X-ray absorption studies of Zn(2+)-binding sites in Escherichia coli transhydrogenase and its betaH91K mutant.
Topics: Amino Acid Substitution; Aspartic Acid; Binding Sites; Cysteine; Escherichia coli Proteins; Glutamic Acid; Histidine; Models, Molecular; Mutation; NADP Transhydrogenases; Protein Binding; Protein Structure, Tertiary; Spectrometry, X-Ray Emission; Zinc | 2010 |
Metabolomic analysis of serum by (1) H NMR spectroscopy in amyotrophic lateral sclerosis.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetone; Adult; Amyotrophic Lateral Sclerosis; Female; Formates; Glutamic Acid; Glutamine; Histidine; Humans; Magnetic Resonance Spectroscopy; Male; Protons; Sensitivity and Specificity | 2010 |
Metastasis suppressor function of NM23-H1 requires its 3'-5' exonuclease activity.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Exonucleases; Female; Glutamic Acid; Histidine; Histidine Kinase; Humans; Lung Neoplasms; Lysine; Melanoma, Experimental; Mice; Mice, Nude; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation, Missense; NM23 Nucleoside Diphosphate Kinases; Protein Conformation; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous | 2011 |
Chemical fragments that hydrogen bond to Asp, Glu, Arg, and His side chains in protein binding sites.
Topics: Arginine; Aspartic Acid; Binding Sites; Databases, Factual; Glutamic Acid; Histidine; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Structure | 2010 |
Avt5p is required for vacuolar uptake of amino acids in the fission yeast Schizosaccharomyces pombe.
Topics: Amino Acid Transport Systems; Amino Acids; Arginine; Biological Transport; Glutamic Acid; Histidine; Lysine; Membrane Proteins; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Tyrosine; Vacuoles; Vesicular Transport Proteins | 2010 |
Requirements for catalysis in the Cre recombinase active site.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Biocatalysis; Catalytic Domain; Glutamic Acid; Histidine; Integrases; Lysine; Models, Molecular; Molecular Sequence Data; Recombination, Genetic; Tryptophan; Tyrosine; Vanadates | 2010 |
Characterization of Peptide Polymer Interactions in Poly(alkylcyanoacrylate) Nanoparticles: A Mass Spectrometric Approach.
Topics: Angiotensin II; Chemistry, Pharmaceutical; Corticotropin-Like Intermediate Lobe Peptide; Cyanoacrylates; Drug Carriers; Enbucrilate; Glutamic Acid; Gonadotropin-Releasing Hormone; Histidine; Hydrogen-Ion Concentration; Insulin; Insulin-Like Growth Factor I; Models, Molecular; Nanoparticles; Nanotechnology; Peptides; Protein Conformation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2010 |
A theoretical study on the catalytic mechanism of Mus musculus adenosine deaminase.
Topics: Adenosine Deaminase; Animals; Catalysis; Energy Transfer; Glutamic Acid; Histidine; Hydroxyl Radical; Kinetics; Mice; Models, Chemical; Models, Molecular; Protein Conformation; Quantum Theory; Zinc | 2010 |
In rat dipeptidyl peptidase III, His⁵⁶⁸ is essential for catalysis, and Glu⁵⁰⁷ or Glu⁵¹² stabilizes the coordination bond between His⁴⁵⁵ or His⁴⁵⁰ and zinc ion.
Topics: Animals; Catalysis; Crystallography, X-Ray; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Glutamic Acid; Histidine; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Rats; Substrate Specificity; Zinc | 2010 |
Moonlighting glutamate formiminotransferases can functionally replace 5-formyltetrahydrofolate cycloligase.
Topics: Animals; Archaea; Carbon-Nitrogen Ligases; Escherichia coli; Folic Acid; Genetic Complementation Test; Genomics; Glutamate Formimidoyltransferase; Glutamic Acid; Histidine; Kinetics; Models, Genetic; Mutation; Phenotype; Recombinant Proteins; Streptococcus pyogenes; Swine | 2010 |
Exploring the use of dimethylsulfate for in vivo proteome footprinting.
Topics: Amino Acid Sequence; Animals; Chromatin; Glutamic Acid; HeLa Cells; Histidine; Histones; Humans; Lysine; Methylation; Molecular Sequence Data; Protein Folding; Protein Multimerization; Proteome; Proteomics; Sulfuric Acid Esters; Xenopus | 2011 |
Evidence of the participation of remote residues in the catalytic activity of Co-type nitrile hydratase from Pseudomonas putida.
Topics: Aspartic Acid; Binding Sites; Catalysis; Glutamic Acid; Histidine; Hydro-Lyases; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Protein Structure, Secondary; Pseudomonas putida | 2011 |
A QM/QM investigation of the hUNG2 reaction surface: the untold tale of a catalytic residue.
Topics: Asparagine; Aspartic Acid; Catalysis; Catalytic Domain; Computer Simulation; DNA Mutational Analysis; Glutamic Acid; Histidine; Humans; Models, Molecular; Proline; Protons; Quantum Theory; Static Electricity; Surface Properties; Uracil-DNA Glycosidase; Water | 2011 |
Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with (99m)Tc, (111)In, and (125)I.
Topics: Animals; Cell Line; Cell Line, Tumor; Cysteine; Female; Glutamic Acid; Histidine; Indium Radioisotopes; Iron Radioisotopes; Liver; Mice; Oligopeptides; Organotechnetium Compounds; Radioisotopes; Receptor, ErbB-2; Recombinant Fusion Proteins; Tissue Distribution | 2011 |
Site-directed mutagenesis of histidine 69 and glutamic acid 148 alters the ribonuclease activity of pea ABR17 (PR10.4).
Topics: Amino Acid Substitution; Catalysis; Glutamic Acid; Histidine; Models, Molecular; Mutagenesis, Site-Directed; Pisum sativum; Plant Proteins; Protein Structure, Tertiary; Recombinant Proteins; Ribonucleases; Substrate Specificity | 2011 |
The pH sensor of the plant K+-uptake channel KAT1 is built from a sensory cloud rather than from single key amino acids.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Plant Stomata; Potassium Channels, Inwardly Rectifying; Thermodynamics | 2012 |
Homology modeling and docking analyses of M. leprae Mur ligases reveals the common binding residues for structure based drug designing to eradicate leprosy.
Topics: Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Bacterial Proteins; Catalytic Domain; Conserved Sequence; Drug Design; Glutamic Acid; Glycine; Histidine; Humans; Hydrogen Bonding; Leprosy; Models, Molecular; Molecular Sequence Data; Mycobacterium leprae; Peptide Synthases; Protein Binding; Protein Structure, Secondary; Structural Homology, Protein; Thermodynamics | 2012 |
Mutation of the sensor kinase chvG in Rhizobium leguminosarum negatively impacts cellular metabolism, outer membrane stability, and symbiosis.
Topics: Arginine; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cell Membrane; DNA, Bacterial; Genes, Bacterial; Glutamic Acid; Histidine; Hydroxybutyrates; Lens Plant; Mutation; Pisum sativum; Polyesters; Polysaccharides; Proline; Protein Kinases; Rhizobium leguminosarum; Signal Transduction; Stress, Physiological; Symbiosis; Transcription Factors; Vicia | 2012 |
The origin and ecological significance of multiple branches for histidine utilization in Pseudomonas aeruginosa PAO1.
Topics: Environment; Formiminoglutamic Acid; Gene Expression Regulation, Bacterial; Genome, Bacterial; Glutamic Acid; Histidine; Mutation; Operon; Phylogeny; Pseudomonas aeruginosa | 2012 |
Effect of amino acids on red pigments and citrinin production in Monascus ruber.
Topics: Alanine; Amino Acids; Citrinin; Culture Media; Fermentation; Glutamic Acid; Histidine; Monascus; Nitrogen; Pigments, Biological; Proline | 2012 |
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.
Topics: Adaptor Proteins, Signal Transducing; Amidohydrolases; Amino Acid Sequence; Animals; Aspartic Acid; B-Cell CLL-Lymphoma 10 Protein; Biocatalysis; Caspases; Catalytic Domain; Crystallography, X-Ray; Cysteine; Diglycerides; DNA Mutational Analysis; Dysentery, Bacillary; Glutamic Acid; Glutamine; HEK293 Cells; HeLa Cells; Histidine; Humans; Immunity, Innate; Inflammation; Mice; Models, Molecular; Molecular Sequence Data; Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein; Neoplasm Proteins; NF-kappa B; Shigella flexneri; TNF Receptor-Associated Factor 6; Ubiquitin-Conjugating Enzymes; Virulence Factors | 2012 |
A salt-bridge controlled by ligand binding modulates the hydrolysis reaction in a GH5 endoglucanase.
Topics: Amino Acid Sequence; Catalytic Domain; Cellulase; Cellulose; Glutamic Acid; Histidine; Hydrolysis; Ligands; Molecular Dynamics Simulation; Protein Conformation; Protons; Sequence Alignment; Substrate Specificity; Tetroses | 2012 |
Efficient expression and purification of recombinant glutaminase from Bacillus licheniformis (GlsA) in Escherichia coli.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; Base Sequence; Enzyme Stability; Escherichia coli; Glutamic Acid; Glutaminase; Histidine; Hydrogen-Ion Concentration; Molecular Sequence Data; Protein Hydrolysates; Recombinant Fusion Proteins; Sequence Alignment; Temperature | 2012 |
Structure and function of ∆1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa.
Topics: Animals; Berberine; Cannabis; Carbon Dioxide; Crystallography, X-Ray; Cysteine; Flavin-Adenine Dinucleotide; Glutamic Acid; Histidine; Intramolecular Oxidoreductases; Mutation; Protein Structure, Tertiary; Psychotropic Drugs; Structure-Activity Relationship; Tyrosine | 2012 |
Alterations in plasma amino acid levels in alcoholic chronic pancreatitis in Japanese.
Topics: Adult; Aged; Amino Acids; Asian People; Case-Control Studies; Exocrine Pancreatic Insufficiency; Female; Food, Formulated; Glutamic Acid; Histidine; Humans; Japan; Male; Methionine; Middle Aged; Pancreatitis, Alcoholic; Serum Albumin | 2012 |
Preparation and characterization of poly(L-histidine)/poly(L-glutamic acid) multilayer on silicon with nanometer-sized surface structures.
Topics: Glutamic Acid; Histidine; Nanotechnology; Photoelectron Spectroscopy; Silicon; Surface Properties | 2012 |
Multiple sensor array of Mn2+, Fe2+, Co2+, Ni2+, Cu2+, and Zn2+ complexes of a triazole linked imino-phenol based calix[4]arene conjugate for the selective recognition of Asp, Glu, Cys, and His.
Topics: Aspartic Acid; Calixarenes; Cysteine; Glutamic Acid; Histidine; Imines; Models, Molecular; Molecular Structure; Organometallic Compounds; Phenols; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Transition Elements; Triazoles | 2012 |
Expanding the active pH range of Escherichia coli glutamate decarboxylase by breaking the cooperativeness.
Topics: Biofuels; Escherichia coli; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Mutation; Protein Engineering | 2013 |
Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family.
Topics: Bacterial Proteins; Carboxy-Lyases; Catalysis; Catalytic Domain; Corynebacterium glutamicum; Crystallography, X-Ray; Glutamic Acid; Histidine; Hydrolases; Multigene Family; Mutation, Missense; Protein Conformation; Thermus thermophilus; Transformation, Bacterial | 2013 |
In vitro degradation of lysine by ruminal fluid-based fermentations and by Fusobacterium necrophorum.
Topics: Acetic Acid; Alanine; Animals; Cattle; Fermentation; Fusobacterium necrophorum; Gastric Juice; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; In Vitro Techniques; Lysine; Methionine; Propionates; Rumen; Tryptophan | 2013 |
Measurement and modeling of acid dissociation constants of tri-peptides containing Glu, Gly, and His using potentiometry and generalized multiplicative analysis of variance.
Topics: Glutamic Acid; Glycine; Histidine; Hydrogen-Ion Concentration; Models, Molecular; Oligopeptides; Potentiometry; Software | 2013 |
Dynamic factors affecting gaseous ligand binding in an artificial oxygen transport protein.
Topics: Binding Sites; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Globins; Glutamic Acid; Heme; Histidine; Kinetics; Ligands; Mutant Proteins; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxygen; Protein Binding; Protein Conformation; Protein Engineering; Protein Folding; Recombinant Proteins; Water | 2013 |
Switchable delivery of small interfering RNA using a negatively charged pH-responsive polyethylenimine-based polyelectrolyte complex.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Drug Screening Assays, Antitumor; Electrolytes; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; Polyethylene Glycols; Polyethyleneimine; RNA, Small Interfering; Structure-Activity Relationship | 2013 |
Direct analysis of formate in human plasma, serum and whole blood by in-line coupling of microdialysis to capillary electrophoresis for rapid diagnosis of methanol poisoning.
Topics: Electric Conductivity; Electrophoresis, Capillary; Formates; Glutamic Acid; Histidine; Humans; Methanol; Microdialysis | 2013 |
Mixed ligand Cu2+ complexes of a model therapeutic with Alzheimer's amyloid-β peptide and monoamine neurotransmitters.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Copper; Glutamic Acid; Glutathione Disulfide; Glycine; Histamine; Histidine; Humans; Ligands; Models, Molecular; Neurotransmitter Agents; Oxyquinoline | 2013 |
A biochemical correlate of dimorphism in a zygomycete Benjaminiella poitrasii: characterization of purified NAD-dependent glutamate dehydrogenase, a target for antifungal agents.
Topics: Ammonium Chloride; Antifungal Agents; Candida albicans; Catalysis; Chromatography, Agarose; Drug Evaluation, Preclinical; Fungal Proteins; Glutamate Dehydrogenase; Glutamic Acid; Histidine; Hyphae; Isoelectric Point; Ketoglutaric Acids; Lysine; Molecular Targeted Therapy; Molecular Weight; Mucorales; NAD; Phosphorylation; Protein Processing, Post-Translational; Substrate Specificity; Triazoles; Yarrowia | 2013 |
Zinc modulation of calcium activity at the photoreceptor terminal: a calcium imaging study.
Topics: Ambystoma; Aniline Compounds; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Chelating Agents; Dose-Response Relationship, Drug; Ethylenediamines; Fluorescent Dyes; Glutamic Acid; Histidine; Microscopy, Fluorescence; Presynaptic Terminals; Retinal Cone Photoreceptor Cells; Xanthenes; Zinc | 2013 |
Structural and biochemical characterization of an active arylamine N-acetyltransferase possessing a non-canonical Cys-His-Glu catalytic triad.
Topics: Amino Acid Sequence; Arylamine N-Acetyltransferase; Bacillus cereus; Base Sequence; Catalytic Domain; Crystallography, X-Ray; Cysteine; DNA Primers; Glutamic Acid; Histidine; Models, Molecular; Molecular Sequence Data; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid | 2013 |
Mutation of the critical pH-gating residues histidine 231 to glutamate increase open probability of outer membrane protein G in planar lipid bilayer.
Topics: Bacterial Outer Membrane Proteins; Escherichia coli Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Ion Channel Gating; Lipid Bilayers; Mutant Proteins; Mutation; Porins | 2013 |
The copper(II) and zinc(II) coordination mode of HExxH and HxxEH motif in small peptides: the role of carboxylate location and hydrogen bonding network.
Topics: Amino Acid Motifs; Circular Dichroism; Copper; Glutamic Acid; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Peptides; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Thermodynamics; Zinc | 2014 |
Cytoprotection by endogenous zinc in the vertebrate retina.
Topics: Animals; Cell Survival; Chelating Agents; Dark Adaptation; Data Interpretation, Statistical; Excitatory Amino Acid Agonists; Eye; Glutamic Acid; Histidine; Kainic Acid; Necrosis; Photoreceptor Cells, Vertebrate; Retina; Skates, Fish; Zinc | 2014 |
How the structure of the large subunit controls function in an oxygen-tolerant [NiFe]-hydrogenase.
Topics: Bacterial Proteins; Catalysis; Crystallography, X-Ray; Genetic Engineering; Glutamic Acid; Histidine; Hydrogen; Hydrogenase; Oxygen; Protein Conformation; Protein Subunits; Salmonella enterica | 2014 |
Formation constants of copper(II) complexes with tripeptides containing Glu, Gly, and His: potentiometric measurements and modeling by generalized multiplicative analysis of variance.
Topics: Analysis of Variance; Coordination Complexes; Copper; Glutamic Acid; Glycine; Histidine; Models, Molecular; Oligopeptides; Potentiometry | 2014 |
Tumor targeting of a cell penetrating peptide by fusing with a pH-sensitive histidine-glutamate co-oligopeptide.
Topics: Animals; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell-Penetrating Peptides; Drug Delivery Systems; Female; Glutamic Acid; Glutathione Transferase; HeLa Cells; Histidine; Humans; Hydrogen-Ion Concentration; Mice; Xenograft Model Antitumor Assays | 2014 |
New force field parameters for metalloproteins I: Divalent copper ion centers including three histidine residues and an oxygen-ligated amino acid residue.
Topics: Aspartic Acid; Copper; Glutamic Acid; Histidine; Metalloproteins; Models, Molecular; Molecular Dynamics Simulation; Thermodynamics; Tyrosine | 2014 |
Plasma amino acid profiles of breast cancer patients early in the trajectory of the disease differ from healthy comparison groups.
Topics: Adolescent; Adult; Amino Acids; Body Composition; Breast Neoplasms; Case-Control Studies; Energy Intake; Female; Glutamic Acid; Glutamine; Histidine; Humans; Leucine; Middle Aged; Threonine | 2014 |
Introducing transglycosylation activity in Bacillus licheniformis α-amylase by replacement of His235 with Glu.
Topics: alpha-Amylases; Amino Acid Sequence; Apraxia, Ideomotor; Bacillus; Binding Sites; Glutamic Acid; Glycosylation; Histidine; Hydrolysis; Models, Molecular; Oligosaccharides | 2014 |
Protective effect of carnosine on febrile seizures in immature mice.
Topics: Animals; Anticonvulsants; Carnosine; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Histamine; Histidine; Histidine Decarboxylase; Male; Mice, Inbred C57BL; Mice, Knockout; Seizures, Febrile | 2015 |
A common late-stage intermediate in catalysis by 2-hydroxyethyl-phosphonate dioxygenase and methylphosphonate synthase.
Topics: Catalysis; Catalytic Domain; Crystallography, X-Ray; Dioxygenases; Glutamic Acid; Histidine; Magnetic Resonance Spectroscopy; Mutation; Organophosphonates; Organophosphorus Compounds; Oxygenases; Protein Conformation | 2015 |
Horizontal membrane-intrinsic α-helices in the stator a-subunit of an F-type ATP synthase.
Topics: Adenosine Triphosphate; Arginine; Chlorophyta; Cryoelectron Microscopy; Glutamic Acid; Histidine; Ion Transport; Lipid Bilayers; Models, Molecular; Protein Multimerization; Protein Structure, Secondary; Protein Subunits; Proton-Translocating ATPases; Protons; Rotation; Water | 2015 |
Characterization of Avt1p as a vacuolar proton/amino acid antiporter in Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems; Amino Acids, Neutral; Antiporters; Aspartic Acid; Biological Transport; gamma-Aminobutyric Acid; Glutamic Acid; Histidine; Intracellular Membranes; Isoleucine; Protons; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Vacuoles | 2015 |
The germline CDH1 c.48 G>C substitution contributes to cancer predisposition through generation of a pro-invasive mutation.
Topics: Amino Acid Substitution; Animals; Antigens, CD; Cadherins; CHO Cells; Cricetinae; Cricetulus; Female; Genetic Predisposition to Disease; Germ-Line Mutation; Glutamic Acid; Histidine; Humans; Neoplasm Invasiveness; Pedigree; Stomach Neoplasms; Young Adult | 2014 |
A Novel Tau Mutation in Exon 12, p.Q336H, Causes Hereditary Pick Disease.
Topics: alpha-Synuclein; Brain; DNA Mutational Analysis; Exons; Glutamic Acid; Histidine; Humans; Male; Middle Aged; Mutation; Pick Disease of the Brain; tau Proteins; Ubiquitin | 2015 |
Computational Examination on the Active Site Structure of a (Peroxo)diiron(III) Intermediate in the Amine Oxygenase AurF.
Topics: Catalytic Domain; Ferric Compounds; Glutamic Acid; Histidine; Mixed Function Oxygenases; Models, Molecular; Molecular Structure; Oxygen; Peroxides; Protons; Quantum Theory; Streptomyces | 2015 |
Glutamate and histidine improve both solvent yields and the acid tolerance response of Clostridium beijerinckii NCP 260.
Topics: Acetone; Amino Acids; Butanols; Clostridium beijerinckii; Fermentation; Genes, Regulator; Glutamate Synthase; Glutamic Acid; Histidine; Solvents; Stress, Physiological | 2016 |
Lactate modulates the intracellular pH sensitivity of human TREK1 channels.
Topics: Action Potentials; Glutamic Acid; HEK293 Cells; Histidine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Point Mutation; Potassium Channels, Tandem Pore Domain | 2016 |
Pre-formulation and systematic evaluation of amino acid assisted permeability of insulin across in vitro buccal cell layers.
Topics: Aspartic Acid; Cell Line, Tumor; Cell Membrane; Cell Membrane Permeability; Cell Survival; Deoxycholic Acid; Electric Impedance; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Lysine; Mouth Mucosa | 2016 |
Topics: Biomarkers; Cholecystitis; Formates; Glutamic Acid; Histidine; Humans; Lactic Acid; Lipoproteins; Metabolomics; Propylene Glycols; Proton Magnetic Resonance Spectroscopy | 2017 |
Engineering the metal sensitive sites in Macrolampis sp2 firefly luciferase and use as a novel bioluminescent ratiometric biosensor for heavy metals.
Topics: Animals; Biosensing Techniques; Cations, Divalent; Cloning, Molecular; Escherichia coli; Fireflies; Gene Expression; Genetic Vectors; Glutamic Acid; Histidine; Kinetics; Luciferases, Firefly; Luminescence; Luminescent Measurements; Mercury; Mutagenesis, Site-Directed; Nickel; Protein Engineering; Recombinant Proteins; Zinc | 2016 |
Strong Impact of an Axial Ligand on the Absorption by Chlorophyll a and b Pigments Determined by Gas-Phase Ion Spectroscopy Experiments.
Topics: Acetylcholine; Aspartic Acid; Chlorophyll; Chlorophyll A; Energy Transfer; Formates; Glutamic Acid; Histidine; Kinetics; Ligands; Magnesium; Models, Molecular; Photosystem II Protein Complex; Pisum sativum; Protein Structure, Secondary; Spectrum Analysis; Static Electricity; Thermodynamics | 2016 |
Translation-dependent bioassay for amino acid quantification using auxotrophic microbes as biocatalysts of protein synthesis.
Topics: beta-Galactosidase; Biological Assay; Calibration; Colorimetry; Genes, Reporter; Glutamic Acid; Glutamine; Green Fluorescent Proteins; Histidine; Lactococcus lactis; Luciferases; Protein Biosynthesis; Sensitivity and Specificity; Spectrometry, Fluorescence; Time Factors; Valine | 2017 |
On the Influence of the Protonation States of Active Site Residues on AChE Reactivation: A QM/MM Approach.
Topics: Acetylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Computer Simulation; Glutamic Acid; Histidine; Models, Chemical; Molecular Structure; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Protons; Quantum Theory; Serine | 2017 |
Amino acid transporter SLC38A3 promotes metastasis of non-small cell lung cancer cells by activating PDK1.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Carcinoma, Non-Small-Cell Lung; Cell Movement; Enzyme Activation; Epithelial-Mesenchymal Transition; Glutamic Acid; Histidine; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Sodium-Calcium Exchanger; Transfection | 2017 |
Enhancing siRNA-based cancer therapy using a new pH-responsive activatable cell-penetrating peptide-modified liposomal system.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Line, Tumor; Cell-Penetrating Peptides; Drug Delivery Systems; Endosomes; Glutamic Acid; Histidine; Humans; Hydrazones; Hydrogen-Ion Concentration; Liposomes; MCF-7 Cells; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Tumor Microenvironment | 2017 |
Rational design of a pH-insensitive cyan fluorescent protein CyPet2 based on the CyPet crystal structure.
Topics: Amino Acid Substitution; Crystallography, X-Ray; Fluorescent Dyes; Glutamic Acid; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Luminescent Proteins; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Conformation, beta-Strand; Protein Engineering; Protein Stability; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Stereoisomerism | 2017 |
Model peptide studies of Ag
Topics: Bacterial Proteins; Binding Sites; Carrier Proteins; Drug Resistance, Bacterial; Glutamic Acid; Histidine; Methionine; Peptide Fragments; Protein Binding; Silver | 2017 |
Effects of three major amino acids found in Japanese broth on glucose metabolism and gastric emptying.
Topics: Adult; Amino Acids; Animals; Aspartic Acid; Blood Glucose; C-Peptide; Cross-Over Studies; Diet; Female; Fishes; Food, Preserved; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Glutamic Acid; Histidine; Humans; Insulin; Japan; Kelp; Male; Oryza | 2018 |
Recognition dynamics of trinuclear copper cluster and associated histidine residues through conserved or semi-conserved water molecules in human Ceruloplasmin: The involvement of aspartic and glutamic acid gates.
Topics: Aspartic Acid; Ceruloplasmin; Copper; Glutamic Acid; Histidine; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Conformation; Oxidoreductases; Structure-Activity Relationship; Water | 2018 |
The C terminus of the bacterial multidrug transporter EmrE couples drug binding to proton release.
Topics: Antiporters; Binding Sites; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Onium Compounds; Organophosphorus Compounds; Protein Binding; Protein Conformation; Protein Domains; Protons | 2018 |
Histone Tail Sequences Balance Their Role in Genetic Regulation and the Need To Protect DNA against Destruction in Nucleosome Core Particles Containing Abasic Sites.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; DNA; DNA Cleavage; Glutamic Acid; Histidine; Histones; Humans; Lysine; Mice; Mutation; Nucleosomes; Saccharomyces cerevisiae; Xenopus laevis | 2019 |
Impact of Buffers on Colloidal Property and Aggregation Propensities of a Bispecific Antibody.
Topics: Antibodies, Bispecific; Buffers; Colloids; Drug Development; Drug Stability; Drug Storage; Dynamic Light Scattering; Glutamic Acid; Histidine; Nuclear Magnetic Resonance, Biomolecular; Protein Aggregates; Proton Magnetic Resonance Spectroscopy | 2019 |
Amino acids profiles of children who stutter compared to their fluent sibling.
Topics: Case-Control Studies; Child; Child, Preschool; Female; Glutamic Acid; Hair; Histidine; Humans; Isoleucine; Male; Siblings; Stuttering; Threonine; Tyrosine | 2020 |
Structural Insights into the Mechanism of the Radical SAM Carbide Synthase NifB, a Key Nitrogenase Cofactor Maturating Enzyme.
Topics: Archaeal Proteins; Binding Sites; Crystallography, X-Ray; Cysteine; Glutamic Acid; Histidine; Iron-Sulfur Proteins; Methanosarcinales; Models, Chemical; Oxidoreductases; Protein Binding; Protein Conformation; S-Adenosylmethionine | 2020 |
Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase.
Topics: Animals; Binding Sites; Biocatalysis; Crystallization; Crystallography, X-Ray; Glutamic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Histidine; Magnesium; Models, Molecular; Protein Conformation; Succinate-CoA Ligases; Succinic Acid; Swine | 2021 |
Engineered pH-Sensitive Protein G/IgG Interaction.
Topics: Bacterial Proteins; Glutamic Acid; Histidine; Humans; Hydrogen-Ion Concentration; Immunoglobulin Fc Fragments; Immunoglobulin G; Mutation; Protein Binding; Protein Domains; Protein Engineering; Streptococcus | 2021 |
Alkylated glutamic acid and histidine derived from protein-adducts indicate exposure to sulfur mustard in avian serum.
Topics: Chemical Warfare Agents; Glutamic Acid; Histidine; Hydroxyeicosatetraenoic Acids; Mustard Gas; Serum Albumin; Serum Albumin, Human; Tandem Mass Spectrometry | 2022 |
An integrated metabonomics study to reveal the inhibitory effect and metabolism regulation of taurine on breast cancer.
Topics: Animals; Arginine; Breast Neoplasms; Choline; Female; Glutamic Acid; Histidine; Humans; Isoleucine; Lactic Acid; Leucine; Lung Neoplasms; Metabolomics; Mice; Taurine; Valine | 2022 |
Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide.
Topics: Disulfides; Glutamic Acid; Histidine; Peptides; Phagocytosis | 2022 |
Amino acids, microbiota-related metabolites, and the risk of incident diabetes among normoglycemic Chinese adults: Findings from the 4C study.
Topics: 2-Aminoadipic Acid; Adult; Alanine; Amino Acids; Asparagine; Diabetes Mellitus, Type 2; Glutamic Acid; Histidine; Homoserine; Humans; Lipids; Methionine; Microbiota; Proline; Uric Acid | 2022 |
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan | 2022 |
Impact of Inhibition of Glutamine and Alanine Transport on Cerebellar Glial and Neuronal Metabolism.
Topics: Acetates; Alanine; Ammonia; Animals; Carbon; Cerebellum; Glucose; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine | 2022 |
Changes in aging-induced kidney dysfunction in mice based on a metabolomics analysis.
Topics: Aging; Animals; Biomarkers; Citrates; Glutamic Acid; Glutamine; Glyoxylates; Histidine; Kidney; Male; Mice; Nucleotides; Purines; Pyruvates; Renal Insufficiency; Tricarboxylic Acids | 2022 |
Endogenous benzoic acid interferes with the signatures of amino acids and thiol compounds through perturbing N-methyltransferase, glutamate-cysteine ligase, and glutathione S-transferase activity in dairy products.
Topics: Amino Acids; Animals; Benzoic Acid; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glutathione Transferase; Goats; Histidine; Methyltransferases; Milk; Phenylalanine; Sulfhydryl Compounds; Tyrosine | 2022 |
Comparison of amino acid digestibility and its additivity determined with slaughter or cecectomy method for yellow-feather chicken.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Chickens; Diet; Digestion; Feathers; Glutamic Acid; Glycine; Glycine max; Histidine; Ileum; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Valine; Zea mays | 2022 |
Separation and fractionation of glutamic acid and histidine via origami isoelectric focusing.
Topics: Amino Acids; Ampholyte Mixtures; Glutamic Acid; Histidine; Hydrogen-Ion Concentration; Isoelectric Focusing; Proteins | 2023 |
The Association between Macrosomia and Amino Acids' Levels in Maternal and Cord Sera: A Case-Control Study.
Topics: Alanine; Amino Acids; Arginine; Case-Control Studies; Chromatography, Liquid; Female; Fetal Macrosomia; Glutamic Acid; Glutamine; Histidine; Humans; Infant, Newborn; Leucine; Methionine; Tandem Mass Spectrometry; Threonine; Tryptophan; Valine | 2023 |
Evaluation of crystalline amino acids as potent stimulatory chemoattractants for the slipper lobster
Topics: Amino Acids; Animals; Betaine; Decapoda; Glutamic Acid; Glycine; Histidine; Nephropidae | 2023 |