glutamic acid has been researched along with guanosine triphosphate in 66 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (10.61) | 18.7374 |
| 1990's | 18 (27.27) | 18.2507 |
| 2000's | 34 (51.52) | 29.6817 |
| 2010's | 5 (7.58) | 24.3611 |
| 2020's | 2 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Hamel, E; Kenney, S; Lin, CM; Skehan, P | 1 |
| Jahr, CE; Nawy, S | 1 |
| Kawai, N; Miwa, A; Ui, M | 1 |
| Baba, A; Iwata, H; Nishiuchi, Y; Tatsuno, T; Uemura, A | 1 |
| Armiger, LC; Choong, YS; Gavin, JB | 1 |
| Hamel, E; Lin, CM | 1 |
| Cook, PF | 1 |
| Hamel, E; Lustbader, J | 1 |
| Costentin, J; Delandre, M; Martres, MP; Protais, P; Schwartz, JC; Sokoloff, P | 1 |
| Brown, PD; Kotera, T | 1 |
| Erecińska, M; Nelson, D | 1 |
| Akopian, A; Witkovsky, P | 1 |
| Kehoe, J | 1 |
| Cerione, RA; Erickson, JW; Mittal, R | 1 |
| Dudler, T; Gelb, MH | 1 |
| Livi, CB; Medeiros, AC; Ramirez, G; Rocha, PC; Rubin, MA; Souza, DO | 1 |
| Haley, BE; Pendergrass, JC | 1 |
| Ikeda, M; Ishida, O; Kikuchi, A; Kishida, S; Matsuura, Y; Murai, H; Okazaki-Kishida, M | 1 |
| Bourne, HR; Farfel, Z; Iiri, T | 1 |
| Horiguchi, Y; Inoue, N; Kashimoto, T; Katahira, J; Masuda, M; Matsuda, M; Sugimoto, N | 1 |
| Peterson, PE; Pierce, J; Smith, TJ | 1 |
| Cardoso, LF; Martini, LH; Ramírez, G; Souza, DO; Tasca, CI | 1 |
| Belló-Klein, A; Ramirez, G; Regner, A; Souza, D | 1 |
| Clark, BF; Knudsen, CR; Pedersen, GN; Rattenborg, T | 1 |
| Clark, BF; Knudsen, CR; Mansilla, F | 1 |
| Artemyev, NO; McEntaffer, RL; Muradov, KG; Natochin, M | 1 |
| Bienengraeber, M; Echtay, KS; Klingenberg, M; Winkler, E | 1 |
| Gao, ZG; Ijzerman, AP; Jacobson, KA; Jiang, Q | 1 |
| Metaxari, M; Plaitakis, A; Shashidharan, P | 1 |
| Berlanga, J; Fando, JL; Manso-Tomico, J; Martín, ME; Muñoz, F; Salinas, M | 1 |
| Fang, J; Peterson, PE; Schmidt, T; Smith, TJ; Stanley, CA | 1 |
| Lamkin, MS; Lindhe, P | 1 |
| Georgopoulos, P; Plaitakis, A; Schousboe, A; Sonnewald, U; Waagepetersen, HS; Zaganas, I | 1 |
| de Wit, JG; den Blaauwen, T; Driessen, AJ; Scheffers, DJ | 1 |
| Porciúncula, LO; Souza, DO; Vinadé, L; Wofchuk, S | 1 |
| Fang, J; Hsu, BY; MacMullen, CM; Poncz, M; Smith, TJ; Stanley, CA | 1 |
| Noda, M | 1 |
| Antunes Soares, FA; Dall'Onder, LP; Frizzo, ME; Lara, DR; Souza, DO; Swanson, RA | 1 |
| Chen, XL; Fukuda, Y; Hashii, M; Higashida, H; Hoshi, N; Hossain, KZ; Mochida, S; Nakanishi, S; Noda, M; Shigemoto, R; Shin, Y; Yokoyama, S; Zhang, JS | 1 |
| Galvez, T; Pin, JP | 1 |
| Fukaya, M; Ide, C; Kimura, K; Kinoshita, N; Matsumoto, N; Watanabe, M | 1 |
| Béraud-Dufour, S; Kalbitzer, HR; Kremer, W; Steiner, G | 1 |
| Goto, M; Hirotsu, K; Miyahara, I; Nakagawa, N; Omi, R | 1 |
| Bunster, M; Hinrichs, MV; Montecino, M; Olate, J | 1 |
| Albasanz, JL; Dalfó, E; Ferrer, I; Martin, M | 2 |
| Dong, H; Hu, W; Li, YZ | 1 |
| Collingridge, GL; Isaac, JT; Lauri, SE; Maingret, F; Mulle, C; Segerstråle, M; Taira, T; Vesikansa, A | 1 |
| Hausmann, S; Shuman, S | 1 |
| Artemyev, NO; Chen, CK; Chen, D; Chen, YJ; Kerov, V; Moussaif, M | 1 |
| Alberghina, L; De Gioia, L; Fantinato, S; Fantucci, P; Manzoni, R; Metalli, D; Sacco, E; Vanoni, M | 1 |
| Santos, TG; Souza, DO; Tasca, CI | 1 |
| Emri, Z; Héja, L; Kardos, J; Lasztóczi, B; Nyikos, L; Simon, A; Szárics, E | 1 |
| Curran, DP; Cushman, M; Day, BW; Ghosh, AK; Hamel, E; Jung, MK; Miller, JH; Nicolaou, KC; Northcote, PT; Paterson, I; Sorensen, EJ | 1 |
| Brown, SD; Chelly, J; Cleak, J; Cowan, NJ; Davies, KE; Dear, N; Flint, J; Fray, M; Harvey, RJ; Huang, GJ; Keays, DA; Molnár, Z; Nolan, P; Oliver, PL; Piñon, MC; Poirier, K; Rawlins, JN; Siebold, C; Tian, G; Valdar, W | 1 |
| Becker, CF; Engelhard, M; Goody, RS; Milić, J; Seidel, R | 1 |
| Lara, DR; Schmidt, AP; Souza, DO | 1 |
| Leipelt, M; Rauch, A; Russwurm, M; Steegborn, C | 1 |
| Stanley, CA | 1 |
| Grigorenko, BL; Khrenova, MG; Mironov, VA; Nemukhin, AV | 1 |
| Bai, R; Hamel, E | 1 |
| Cheng, Z; Lin, M; Liu, H; Niu, H; Rikihisa, Y; Xiong, Q; Yamamoto, A | 1 |
| Smith, HQ; Smith, TJ | 1 |
| Bhattacharya, A; Bhattacharya, S; Patra, KK | 1 |
| Fraser, ME; Huang, J | 1 |
| Alfonso, C; Margolin, W; Monterroso, B; Paccione, G; Rivas, G; Robles-Ramos, MÁ; Sobrinos-Sanguino, M; Zorrilla, S | 1 |
5 review(s) available for glutamic acid and guanosine triphosphate
| Article | Year |
|---|---|
Inhibition of brain tubulin-guanosine 5'-triphosphate interactions by mercury: similarity to observations in Alzheimer's diseased brain.
Topics: Administration, Inhalation; Alzheimer Disease; Animals; Binding Sites; Brain; Chelating Agents; Edetic Acid; Egtazic Acid; Glutamic Acid; Guanosine Triphosphate; Humans; Isotope Labeling; Mercury; Microtubules; Nucleotides; Rats; Tubulin | 1997 |
[Mechanism of glucose-induced insulin secretion].
Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Calcium; Glucose; Glutamic Acid; Guanosine Triphosphate; Humans; Insulin; Insulin Secretion; Malonyl Coenzyme A; Potassium Channels | 2002 |
[How do G-protein-coupled receptors work? The case of metabotropic glutamate and GABA receptors].
Topics: Animals; Dimerization; Enzyme Activation; gamma-Aminobutyric Acid; Glutamic Acid; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Models, Biological; Models, Molecular; Protein Conformation; Protein Structure, Tertiary; Receptors, GABA; Receptors, Metabotropic Glutamate; Structure-Activity Relationship | 2003 |
Proposal of a guanine-based purinergic system in the mammalian central nervous system.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Behavior, Animal; Brain; Glutamic Acid; Guanine Nucleotides; Guanosine; Guanosine Triphosphate; Humans; Neuroprotective Agents; Receptors, Purinergic P1; Receptors, Purinergic P2 | 2007 |
Regulation of glutamate metabolism and insulin secretion by glutamate dehydrogenase in hypoglycemic children.
Topics: Amino Acids; Animals; Brain; Congenital Hyperinsulinism; Dietary Proteins; Female; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Hyperammonemia; Insulin; Insulin Secretion; Male; Mice; Mutation | 2009 |
61 other study(ies) available for glutamic acid and guanosine triphosphate
| Article | Year |
|---|---|
Highly variable effects of beryllium and beryllium fluoride on tubulin polymerization under different reaction conditions: comparison of assembly reactions dependent on microtubule-associated proteins, glycerol, dimethyl sulfoxide, and glutamate.
Topics: Animals; Beryllium; Brain; Cattle; Dimethyl Sulfoxide; Fluorides; Glutamates; Glutamic Acid; Glycerol; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Magnesium Sulfate; Microtubule-Associated Proteins; Sodium Fluoride; Tubulin | 1991 |
Suppression by glutamate of cGMP-activated conductance in retinal bipolar cells.
Topics: 1-Methyl-3-isobutylxanthine; Aminobutyrates; Animals; Cell Membrane; Cyclic GMP; Electric Conductivity; Glutamates; Glutamic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Photoreceptor Cells; Receptors, Glutamate; Receptors, Neurotransmitter; Retina; Second Messenger Systems; Thionucleotides; Urodela | 1990 |
Pertussis toxin blocks presynaptic glutamate receptors--a novel 'glutamateB' receptor in the lobster neuromuscular synapse.
Topics: Animals; Glutamates; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Membrane Potentials; Nephropidae; Neuromuscular Junction; Neurotoxins; Pertussis Toxin; Receptors, Glutamate; Receptors, Neurotransmitter; Thionucleotides; Virulence Factors, Bordetella | 1987 |
Inhibition by forskolin of excitatory amino acid-induced accumulation of cyclic AMP in guinea pig hippocampal slices.
Topics: Adenosine; Amino Acids; Animals; Aspartic Acid; Chlorides; Colforsin; Cyclic AMP; Cysteine; Drug Interactions; Ethylmaleimide; Glutamates; Glutamic Acid; Guanosine Triphosphate; Guinea Pigs; Hippocampus; Histamine; Male; N-Methylaspartate; Neurotransmitter Agents; Veratridine | 1988 |
Effects of glutamic acid on cardiac function and energy metabolism of rat heart during ischaemia and reperfusion.
Topics: Adenine Nucleotides; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Energy Metabolism; Glutamates; Glutamic Acid; Guanosine Triphosphate; Heart; Heart Rate; Male; Myocardium; Perfusion; Phosphocreatine; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Stabilization of the colchicine-binding activity of tubulin by organic acids.
Topics: Animals; Carboxylic Acids; Cattle; Colchicine; DEAE-Cellulose; Glutamates; Glutamic Acid; Guanosine Triphosphate; Organophosphorus Compounds; Tubulin | 1981 |
Kinetic studies to determine the mechanism of regulation of bovine liver glutamate dehydrogenase by nucleotide effectors.
Topics: Adenosine Diphosphate; Animals; Binding, Competitive; Cattle; Deuterium; Dose-Response Relationship, Drug; Enzyme Activation; Glutamate Dehydrogenase; Glutamates; Glutamic Acid; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Liver; NADP | 1982 |
Di-and triphosphate derivatives of acyclo- and arabinosylguanine. Effects on the polymerization of purified tubulin.
Topics: Animals; Arabinonucleosides; Brain; Cattle; Glutamates; Glutamic Acid; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Structure-Activity Relationship; Tubulin | 1982 |
Selection of dopamine antagonists discriminating various behavioral responses and radioligand binding sites.
Topics: Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Corpus Striatum; Discrimination, Psychological; Domperidone; Dopamine Antagonists; Glutamates; Glutamic Acid; Guanosine Triphosphate; Humans; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Stereotyped Behavior; Subcellular Fractions | 1984 |
Activation of chloride currents in choroid plexus by GTP-gamma-S and cyclic-AMP.
Topics: Adenosine Triphosphate; Animals; Chloride Channels; Choroid Plexus; Cyclic AMP; Epithelium; Glutamic Acid; Guanosine Triphosphate; Patch-Clamp Techniques; Rats | 1994 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine; Guanosine Diphosphate; Guanosine Triphosphate; Lactates; Lactic Acid; Male; Neurotransmitter Agents; Nitro Compounds; Oxygen Consumption; Phosphocreatine; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Synaptosomes | 1994 |
Modulation of transient outward potassium current by GTP, calcium, and glutamate in horizontal cells of the Xenopus retina.
Topics: Animals; Calcium; Cells, Cultured; Glutamates; Glutamic Acid; GTP-Binding Proteins; Guanosine Triphosphate; Membrane Potentials; Neurons; Photoreceptor Cells; Potassium Channels; Retinal Ganglion Cells; Synaptic Transmission; Xenopus laevis | 1994 |
Glutamate activates a K+ conductance increase in Aplysia neurons that appears to be independent of G proteins.
Topics: Animals; Aplysia; Beryllium; Cholinergic Agonists; Dialysis; Electric Conductivity; Excitatory Amino Acid Agonists; Fluorides; Glutamic Acid; GTP-Binding Proteins; Guanosine Triphosphate; Neurons; Pertussis Toxin; Potassium; Virulence Factors, Bordetella | 1994 |
Uncoupling of GTP binding from target stimulation by a single mutation in the transducin alpha subunit.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate Ribose; Alanine; Animals; Base Sequence; Cattle; Enzyme Activation; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Molecular Sequence Data; Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Fusion Proteins; Rhodopsin; Transducin | 1996 |
Palmitoylation of Ha-Ras facilitates membrane binding, activation of downstream effectors, and meiotic maturation in Xenopus oocytes.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Female; Glutamic Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Insulin; Kinetics; Meiosis; Oocytes; Palmitic Acid; Palmitic Acids; Progesterone; Protein Prenylation; Protein Processing, Post-Translational; ras Proteins; Sequence Tagged Sites; Xenopus laevis | 1996 |
Effect of guanine nucleotides on [3H]glutamate binding and on adenylate cyclase activity in rat brain membranes.
Topics: Adenylyl Cyclases; Animals; Brain; Cell Membrane; Glutamic Acid; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Magnesium; Male; Rats; Rats, Wistar; Sodium; Thionucleotides; Tritium | 1997 |
Characterization of Ral GDP dissociation stimulator-like (RGL) activities to regulate c-fos promoter and the GDP/GTP exchange of Ral.
Topics: Animals; Cell Cycle Proteins; Cell Line; COS Cells; Genes, fos; Glutamic Acid; Glycine; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Mutagenesis, Site-Directed; Phosphoprotein Phosphatases; Point Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; ras Proteins; ras-GRF1; Recombinant Fusion Proteins; Sequence Deletion; Signal Transduction; Spodoptera; Transfection; Valine | 1997 |
Conditional activation defect of a human Gsalpha mutant.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Arginine; Cell Line; Conserved Sequence; Cyclic AMP; Glutamic Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Humans; Isoproterenol; Kinetics; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Point Mutation; Protein Conformation; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Spodoptera; Transfection | 1997 |
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho.
Topics: Actins; Amino Acid Sequence; Amino Acid Substitution; Animals; Bacterial Toxins; Bordetella bronchiseptica; Cell Line; Glutamic Acid; Glutamine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Recombinant Proteins; rhoA GTP-Binding Protein; Sequence Alignment; Transfection; Transglutaminases; Virulence Factors, Bordetella | 1997 |
Crystallization and characterization of bovine liver glutamate dehydrogenase.
Topics: Animals; Cattle; Crystallization; Crystallography, X-Ray; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Liver; Models, Structural; NAD; Polyethylene Glycols; Protein Binding; Protein Conformation; Rotation | 1997 |
Guanine nucleotides inhibit cAMP accumulation induced by metabotropic glutamate receptor activation.
Topics: Animals; Cyclic AMP; Cycloleucine; Glutamic Acid; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Neurotoxins; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thionucleotides | 1998 |
Effects of guanine nucleotides on glutamate-induced chemiluminescence in rat hippocampal slices submitted to hypoxia.
Topics: Animals; Cyclic AMP; Dizocilpine Maleate; Female; Glutamic Acid; Guanine Nucleotides; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Hypoxia; In Vitro Techniques; Luminescent Measurements; Rats; Rats, Wistar | 1998 |
The role of Glu259 in Escherichia coli elongation factor Tu in ternary complex formation.
Topics: Amino Acid Sequence; Conserved Sequence; Drug Stability; Escherichia coli; Glutamic Acid; GTP Phosphohydrolase-Linked Elongation Factors; Guanosine Diphosphate; Guanosine Triphosphate; Hot Temperature; Hydrogen Bonding; Mutagenesis, Site-Directed; Peptide Elongation Factor Tu; Protein Conformation; RNA, Transfer, Phe; Structure-Activity Relationship | 1998 |
Mutational analysis of Glu272 in elongation factor 1A of E. coli.
Topics: Bacterial Proteins; DNA Mutational Analysis; Escherichia coli; Glutamic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Mutagenesis, Site-Directed; Peptide Chain Elongation, Translational; Peptide Elongation Factor Tu; RNA, Transfer, Amino Acyl | 1998 |
Rhodopsin recognition by mutant G(s)alpha containing C-terminal residues of transducin.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Glutamic Acid; Glycine; GTP-Binding Protein alpha Subunits, Gs; Guanosine Diphosphate; Guanosine Triphosphate; Models, Molecular; Mutagenesis, Site-Directed; Recombinant Fusion Proteins; Rhodopsin; Transducin | 2000 |
Site-directed mutagenesis identifies residues in uncoupling protein (UCP1) involved in three different functions.
Topics: Adipose Tissue, Brown; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Binding Sites; Carrier Proteins; Chlorides; Cricetinae; Electron Transport; Glutamic Acid; Glutamine; Guanosine Triphosphate; Ion Channels; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Mutagenesis, Site-Directed; Protons; Saccharomyces cerevisiae; Uncoupling Agents; Uncoupling Protein 1 | 2000 |
Site-directed mutagenesis studies of human A(2A) adenosine receptors: involvement of glu(13) and his(278) in ligand binding and sodium modulation.
Topics: Animals; Binding, Competitive; Drug Interactions; Glutamic Acid; Guanosine Triphosphate; Histidine; Humans; In Vitro Techniques; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sodium; Triazines; Triazoles; Tritium | 2000 |
Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.
Topics: Adenosine Diphosphate; Allosteric Regulation; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Isoenzymes; Ketoglutaric Acids; Leucine; Nerve Tissue; Oxidation-Reduction; Recombinant Proteins; Spodoptera; Transfection | 2000 |
Ischemia-induced phosphorylation of initiation factor 2 in differentiated PC12 cells: role for initiation factor 2 phosphatase.
Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cell Survival; Enzyme Inhibitors; Eukaryotic Initiation Factor-2; Glutamic Acid; Guanosine Triphosphate; Hypoxia-Ischemia, Brain; Neurons; PC12 Cells; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Proteins; Rats | 2000 |
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Animals; Catalytic Domain; Cattle; Crystallography; Gene Expression Regulation, Enzymologic; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Ketoglutaric Acids; Ligands; Models, Molecular; NAD; NADP; Purines; Species Specificity | 2001 |
Purification of kinase activity from primate parotid glands.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Chromatography, Affinity; Enzyme Inhibitors; Enzymes, Immobilized; Glutamic Acid; Glycoproteins; Golgi Apparatus; Guanosine Triphosphate; Heparin; Histatins; Hydrogen-Ion Concentration; Macaca fascicularis; Parotid Gland; Phosphopeptides; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Salivary Proteins and Peptides; Serine; Substrate Specificity | 2001 |
Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebellum; Cerebral Cortex; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Kinetics; Mice; Neurons | 2001 |
GTP hydrolysis of cell division protein FtsZ: evidence that the active site is formed by the association of monomers.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Calcium; Cysteine; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Escherichia coli; Glutamic Acid; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Light; Magnesium; Microscopy, Electron; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Scattering, Radiation; Sequence Homology, Amino Acid; Time Factors | 2002 |
Guanine based purines inhibit [(3)H]glutamate and [(3)H]AMPA binding at postsynaptic densities from cerebral cortex of rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agonists; Glutamic Acid; Guanine; Guanosine Monophosphate; Guanosine Triphosphate; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microscopy, Electron; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Purines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glutamate; Subcellular Fractions; Synaptic Membranes | 2002 |
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Site; Animals; Binding Sites; Cattle; Chaperonin 10; Chaperonin 60; Crystallography, X-Ray; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Ketoglutaric Acids; Mitochondria; Models, Molecular; Mutagenesis, Site-Directed; Mutation | 2002 |
Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake.
Topics: Adenosine Diphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Guanine; Guanosine; Guanosine Monophosphate; Guanosine Triphosphate; Rats; Rats, Wistar | 2003 |
Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase; Animals; Cell Membrane; Cells, Cultured; Cholera Toxin; Enzyme Activation; Glioma; Glutamic Acid; Guanosine Triphosphate; Mice; Mice, Knockout; Neuroblastoma; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Retina; Signal Transduction; Superior Cervical Ganglion | 2003 |
Mammalian septin Sept2 modulates the activity of GLAST, a glutamate transporter in astrocytes.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Brain; Glutamic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Mice; Organ Specificity; Phosphoric Monoester Hydrolases | 2004 |
Conformational states of the small G protein Arf-1 in complex with the guanine nucleotide exchange factor ARNO-Sec7.
Topics: ADP-Ribosylation Factor 1; Catalysis; Catalytic Domain; Escherichia coli; Glutamic Acid; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Guanosine Triphosphate; Ions; Magnesium; Magnetic Resonance Spectroscopy; Nucleotides; Phosphorus; Protein Binding; Protein Conformation | 2004 |
Crystal structures of CTP synthetase reveal ATP, UTP, and glutamine binding sites.
Topics: Binding Sites; Carbon-Nitrogen Ligases; Crystallography, X-Ray; Cytidine Triphosphate; Glutamic Acid; Glutaminase; Guanosine Triphosphate; Models, Molecular; Thermus thermophilus; Uridine Triphosphate | 2004 |
Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate.
Topics: Adenylyl Cyclases; Arginine; Conserved Sequence; Crystallography, X-Ray; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Mutation; Protein Structure, Tertiary | 2004 |
Abnormal metabotropic glutamate receptor expression and signaling in the cerebral cortex in diffuse Lewy body disease is associated with irregular alpha-synuclein/phospholipase C (PLCbeta1) interactions.
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Cell Fractionation; Cell Membrane; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Guanosine Triphosphate; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Lewy Body Disease; Male; Membrane Proteins; Microscopy, Confocal; Middle Aged; Nerve Tissue Proteins; Postmortem Changes; Proline; Propionates; Protein Binding; Quisqualic Acid; Radioligand Assay; Receptors, Glutamate; Signal Transduction; Synaptosomal-Associated Protein 25; Synucleins; Tritium; Type C Phospholipases | 2004 |
Analysis of purified tubulin in high concentration of glutamate for application in high throughput screening for microtubule-stabilizing agents.
Topics: Chromatography, DEAE-Cellulose; Combinatorial Chemistry Techniques; Drug Evaluation, Preclinical; Glutamic Acid; Guanosine Triphosphate; Microscopy, Electron; Microtubules; Polymers; Tubulin | 2004 |
Endogenous activation of kainate receptors regulates glutamate release and network activity in the developing hippocampus.
Topics: Animals; Animals, Newborn; Aspartic Acid; Baclofen; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Furans; GABA Agonists; GABA Antagonists; Glutamic Acid; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Interneurons; Isoquinolines; Isoxazoles; Membrane Potentials; Mice; Mice, Knockout; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Probability; Receptors, Kainic Acid | 2005 |
Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Binding, Competitive; Disease Progression; Down-Regulation; Enzyme Activation; Female; Frontal Lobe; Glutamic Acid; Guanosine Triphosphate; Humans; Isoenzymes; Lewy Body Disease; Male; Middle Aged; Neurons; Phospholipase C beta; Radioligand Assay; Receptors, Metabotropic Glutamate; Signal Transduction; Type C Phospholipases | 2005 |
Giardia lamblia RNA cap guanine-N2 methyltransferase (Tgs2).
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Catalysis; Centrifugation, Density Gradient; Dose-Response Relationship, Drug; Giardia lamblia; Glutamic Acid; Glycerol; Green Fluorescent Proteins; Guanine; Guanosine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Methylation; Methyltransferases; Molecular Sequence Data; Recombinant Proteins; RNA; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Transfection; tRNA Methyltransferases; Tryptophan | 2005 |
Transducin activation state controls its light-dependent translocation in rod photoreceptors.
Topics: Adaptation, Ocular; Animals; Antibodies, Monoclonal; Biological Transport; Dark Adaptation; Dipeptides; Fluorescent Antibody Technique; Gene Expression; Glutamic Acid; GTP Phosphohydrolases; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hydrolysis; Light; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutagenesis; Retina; Retinal Rod Photoreceptor Cells; RGS Proteins; Transducin | 2005 |
The isolated catalytic hairpin of the Ras-specific guanine nucleotide exchange factor Cdc25Mm retains nucleotide dissociation activity but has impaired nucleotide exchange activity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Buffers; Catalysis; Catalytic Domain; Cell Line, Transformed; Cell Transformation, Neoplastic; Crystallography, X-Ray; Down-Regulation; Escherichia coli; Fibroblasts; Genes, Dominant; Genes, ras; Genes, Reporter; Glutamic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Homozygote; Luciferases; Mice; Models, Molecular; Molecular Sequence Data; NIH 3T3 Cells; ortho-Aminobenzoates; Protein Structure, Secondary; ras-GRF1; Sequence Homology, Amino Acid; Temperature | 2005 |
GTP uptake into rat brain synaptic vesicles.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Brain; Ca(2+) Mg(2+)-ATPase; Cold Temperature; Enzyme Inhibitors; Glutamic Acid; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Macrolides; Male; Rats; Rats, Wistar; Synaptic Vesicles; Time Factors | 2006 |
Suppression of neuronal network excitability and seizure-like events by 2-methyl-4-oxo-3H-quinazoline-3-acetyl piperidine in juvenile rat hippocampus: involvement of a metabotropic glutamate receptor.
Topics: Age Factors; Animals; Anticonvulsants; Binding Sites; Calcium Channels; Cell Membrane; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine Triphosphate; Hippocampus; Male; Nerve Net; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Piperidines; Protein Subunits; Pyramidal Cells; Quinazolines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synaptic Transmission | 2006 |
Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Drug Synergism; Glutamic Acid; Guanosine Triphosphate; Humans; Lactones; Macrolides; Microtubule-Associated Proteins; Models, Molecular; Paclitaxel; Taxoids; Temperature; Tubulin; Tumor Cells, Cultured | 2006 |
Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans.
Topics: Amino Acid Sequence; Animals; Anxiety; Behavior, Animal; Cell Movement; Cerebral Cortex; Chromosome Mapping; Dimerization; DNA Mutational Analysis; Female; Glutamic Acid; Guanosine Triphosphate; Hippocampus; Humans; Male; Memory Disorders; Mice; Mice, Mutant Strains; Molecular Sequence Data; Mutation; Neurons; Phenotype; Serine; Tubulin | 2007 |
Semisynthesis of H-Ras with a glutamic acid methylester at position 61.
Topics: Catalysis; Escherichia coli; Esters; Glutamic Acid; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrogen Bonding; Hydrolysis; Models, Molecular; Mutation; Peptides; Protein Folding; ras Proteins | 2008 |
Crystal structure of the guanylyl cyclase Cya2.
Topics: Adenosine Triphosphate; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cyanobacteria; Glutamic Acid; Guanosine Triphosphate; Guanylate Cyclase; Hydrogen Bonding; Protein Binding; Substrate Specificity; Synechocystis | 2008 |
Why does mutation of Gln61 in Ras by the nitro analog NGln maintain activity of Ras-GAP in hydrolysis of guanosine triphosphate?
Topics: Glutamic Acid; Glutamine; Guanosine Triphosphate; Hydrolysis; Mutation; ras Proteins | 2015 |
(-)-Rhazinilam and the diphenylpyridazinone NSC 613241: Two compounds inducing the formation of morphologically similar tubulin spirals but binding apparently to two distinct sites on tubulin.
Topics: Alkaloids; Binding Sites; Dose-Response Relationship, Drug; Glutamic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Indolizines; Lactams; Ligands; Microscopy, Electron; Protein Binding; Pyridazines; Pyridines; Stereoisomerism; Temperature; Tubulin | 2016 |
Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase.
Topics: Adenine; Animals; Autophagosomes; Autophagy; Autophagy-Related Protein 5; Bacterial Proteins; Beclin-1; Cell Membrane; Cell Proliferation; Class III Phosphatidylinositol 3-Kinases; Dogs; Ehrlichia chaffeensis; Ehrlichiosis; Enzyme Activation; Glutamic Acid; Glutamine; Guanosine Triphosphate; HEK293 Cells; Host-Pathogen Interactions; Humans; Huntingtin Protein; Inclusion Bodies; Mutant Proteins; Protein Binding; rab5 GTP-Binding Proteins; Signal Transduction; Sirolimus; Ubiquitination | 2016 |
Identification of a Novel Activator of Mammalian Glutamate Dehydrogenase.
Topics: Adenosine Diphosphate; Allosteric Regulation; Amino Acids, Cyclic; Animals; Binding, Competitive; Biocatalysis; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Glutamate Dehydrogenase; Glutamic Acid; Guanosine Triphosphate; Humans; Kinetics; Models, Molecular; NAD; Protein Binding; Protein Domains; Pyrimidines; Spectrometry, Fluorescence; Sulfonamides | 2016 |
Uncovering allostery and regulation in SAMHD1 through molecular dynamics simulations.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Substitution; Deoxyadenine Nucleotides; Glutamic Acid; Guanosine Triphosphate; Humans; Kinetics; Magnesium; Molecular Dynamics Simulation; Monomeric GTP-Binding Proteins; Mutation; Phosphorylation; Protein Binding; Protein Conformation, alpha-Helical; Protein Interaction Domains and Motifs; Protein Multimerization; Protein Structure, Tertiary; SAM Domain and HD Domain-Containing Protein 1; Substrate Specificity; Threonine | 2017 |
Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase.
Topics: Animals; Binding Sites; Biocatalysis; Crystallization; Crystallography, X-Ray; Glutamic Acid; Guanosine Diphosphate; Guanosine Triphosphate; Histidine; Magnesium; Models, Molecular; Protein Conformation; Succinate-CoA Ligases; Succinic Acid; Swine | 2021 |
Lipid Surfaces and Glutamate Anions Enhance Formation of Dynamic Biomolecular Condensates Containing Bacterial Cell Division Protein FtsZ and Its DNA-Bound Regulator SlmA.
Topics: Anions; Biomolecular Condensates; Carrier Proteins; Cell Division; Cytoskeletal Proteins; DNA; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Guanosine Triphosphate; Lipid Bilayers | 2022 |