glutamic acid has been researched along with glucose, (beta-d)-isomer in 57 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (3.51) | 18.7374 |
1990's | 11 (19.30) | 18.2507 |
2000's | 13 (22.81) | 29.6817 |
2010's | 25 (43.86) | 24.3611 |
2020's | 6 (10.53) | 2.80 |
Authors | Studies |
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Rupitz, K; Trimbur, D; Warren, RA; Withers, SG | 1 |
Aebersold, R; Gilkes, NR; Kilburn, DG; Tull, D; Warren, RA; Withers, SG | 1 |
Alvarez, M; Bracht, A; Kelmer Bracht, A | 1 |
Keefer, CL; Tasca, RJ | 1 |
Bannai, S; Fujiwara, K; Sagara, J; Sato, H | 1 |
Le Rudulier, D; Pocard, JA; Smith, GM; Smith, LT | 1 |
Borriss, R; Heinemann, U; Keitel, T; Simon, O | 1 |
Aebersold, R; Gilkes, NR; Meinke, A; Tull, D; Wang, Q; Warren, RA; Withers, SG | 1 |
Asanami, S; Kim, JP; Nitta, Y; Sakiyama, F; Toda, H | 1 |
Capalbo, L; Ciaramella, M; Moracci, M; Rossi, M | 1 |
Grubb, JH; He, S; Sly, WS; Withers, SG; Wong, AW | 1 |
Ciaramella, M; Moracci, M; Perugino, G; Rossi, M; Trincone, A | 1 |
Hegg, CC; Thayer, SA | 1 |
Geisslinger, G; Tegeder, I; Vetter, G | 1 |
Beksan, E; Blank, I; Fay, LB; Hofmann, T; Robert, F; Schieberle, P; Schlichtherle-Cerny, H | 1 |
Gomez, L; Perez, Y; Simpson, BK; Valdivia, A; Villalonga, R | 1 |
Coste, O; Ehnert, C; Geisslinger, G; Marian, C; Niederberger, E; Schmidtko, A | 1 |
Zeng, X; Zhang, K; Zhang, L; Zhang, S; Zheng, X | 1 |
Chen, FK; Huang, ZB; Wu, Z; Zou, LB | 1 |
Zeng, X; Zhang, S; Zhang, Y; Zheng, X | 1 |
Bie, X; Lu, Y; Xu, X | 1 |
Liu, J; Ma, H; Wang, C; Zhang, D | 1 |
Cao, W; Chen, L; Guo, YY; Liu, JC; Sun, WJ; Sun, XL; Xu, ZH; Zhang, XN; Zhao, MG | 1 |
Abdullaev, IF; Harrigan, TJ; Jourd'heuil, D; Mongin, AA | 1 |
Chen, X; Ding, F; Gu, X; Liu, J | 1 |
Bian, ZX; Chen, HL; Li, Z; Sung, JJ; Xu, HX; Zhang, HQ; Zhang, XJ | 1 |
ArunaDevi, R; Bhadoria, BK; Kumar, D; Kumar, S; Lata, S; Ramteke, VD; Sankar, P; Tandan, SK | 1 |
Feng, CR; Huang, Z; Li, ZY; Mao, QQ; Pan, AJ; Zhong, XM | 1 |
Bie, X; Liu, H; Liu, M; Wan, H; Yang, J; Zhang, G; Zhang, Y | 1 |
Circosta, C; Occhiuto, F; Palumbo, DR; Spadaro, F | 1 |
Liu, C; Liu, Y; Sheng, X; Wang, J; Zhao, Y | 1 |
Behrends, V; Bundy, JG; Jenkins, VA; Robertson, BD; Williams, KJ | 1 |
Gao, YS; Liu, W; Song, SW; Su, BL; Wang, ZS; Zhang, X | 1 |
Fukuda, M; Hino, H; Ishii, E; Suzuki, Y; Takahashi, H; Tanaka, J | 1 |
Li, X; Ou, Y; Sun, R; Wang, K; Wu, D | 1 |
Cechinel Filho, V; de Campos Buzzi, F; Klein-Júnior, LC; Moreira, J | 1 |
Kapoor, S | 1 |
Tan, QR; Wang, D; Zhang, ZJ | 1 |
Cheng, JM; Cheng, L; Gu, JW; Kong, B; Kuang, YQ; Ma, Y; Yang, T; Yang, WT; Yang, XK | 1 |
Ahn, HJ; Kim, JH; Kim, YW; Li, C | 1 |
Hu, Y; Jiang, G; Li, J; Li, Q; Wu, H | 1 |
Huang, J; Sun, C; Wang, M; Wu, B; Xian, H; Yang, Y; Zhao, J; Zheng, Y | 1 |
Liu, Y; Lu, J; Meng, Q; Teng, L; Wang, D; Wang, Z; Xie, J | 1 |
Chen, YY; Huang, HJ; Qu, QM; Xia, NG; Ye, Q; Yin, WY; Zhang, Y | 1 |
Ahn, SM; Choi, BT; Choi, YW; Lee, SY; Shin, HK; Wang, Z | 1 |
Khatter, S; Linseman, DA; Miller, K; Ross, EK; Winter, AN | 1 |
Chen, A; Lin, Y; Wang, H; Wang, X; Xu, W; Yu, L; Zhang, Y | 1 |
Beneke, S; Delp, J; Dietrich, DR; Gutbier, S; Leist, M; Schlichenmaier, N; Secker, PF | 1 |
Chen, A; Li, S; Ma, J; Wang, C; Wang, X; Xin, Z; Zhang, J | 1 |
Li, Q; Liao, XY; Liu, XJ; Liu, YD; Lu, D; Mu, ZH; Qi, YH; Qian, ZY; Wan, Q; Wang, Q; Wang, X; Yang, ZH; Zhang, MY; Zhu, R; Zou, YY | 1 |
Huang, Y; Long, H; Ruan, J; Wang, C; Zhang, M | 1 |
Cheng, H; Chu, J; Jiang, T; Li, Q; Su, J; Wang, Q; Wang, X | 1 |
Chanvorachote, P; Sukprasansap, M; Tencomnao, T | 1 |
Liu, QQ; Luo, L; Sun, T; Tian, QQ; Wang, WJ; Yang, L; Yang, Q; Zhang, K; Zhang, W; Zhao, MG | 1 |
Cao, YJ; Hao, JC; He, XZ; Jing, HL; Shang, B; Wang, X; Wang, ZL; Yang, KL | 1 |
Cao, AM; Fatemi, F; Margeat, E; Pin, JP; Quast, RB; Rondard, P | 1 |
Chang, CY; Chen, MF; Chiou, TW; Chiu, IM; Harn, HJ; Ho, TJ; Li, X; Lin, SZ; Liu, CA; Su, HL; Ting, HC; Tsai, YJ; Yang, HI | 1 |
57 other study(ies) available for glutamic acid and glucose, (beta-d)-isomer
Article | Year |
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Mechanistic consequences of mutation of the active site nucleophile Glu 358 in Agrobacterium beta-glucosidase.
Topics: Asparagine; Aspartic Acid; beta-Glucosidase; Binding Sites; Deuterium; Drug Stability; Glucosides; Glutamates; Glutamic Acid; Glutamine; Glycosylation; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Rhizobium; Structure-Activity Relationship | 1992 |
Glutamic acid 274 is the nucleophile in the active site of a "retaining" exoglucanase from Cellulomonas fimi.
Topics: Actinomycetales; Amino Acid Sequence; beta-Glucosidase; Binding Sites; Cellulase; Enzyme Activation; Glucan 1,3-beta-Glucosidase; Glucosides; Glutamates; Glutamic Acid; Glycoside Hydrolases; Molecular Sequence Data; Xylan Endo-1,3-beta-Xylosidase | 1991 |
Effects of Stevia rebaudiana natural products on rat liver mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Diterpenes; Diterpenes, Kaurane; Glucosides; Glutamates; Glutamic Acid; In Vitro Techniques; Mitochondria, Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxygen Consumption; Phosphorylation; Plant Extracts; Plants, Medicinal; Proteins; Rats; Sweetening Agents; Terpenes | 1985 |
Modulation of amino acid transport in preimplantation mouse embryos by low concentrations of non-ionic and zwitterionic detergents.
Topics: Amino Acids; Animals; Biological Transport, Active; Blastocyst; Cleavage Stage, Ovum; Detergents; Female; Glucosides; Glutamates; Glutamic Acid; Leucine; Methionine; Mice; Octoxynol; Phenylalanine; Polyethylene Glycols; Pregnancy; Quaternary Ammonium Compounds; Surface-Active Agents | 1984 |
Induction of cystine transport activity in mouse peritoneal macrophages by bacterial lipopolysaccharide.
Topics: Amino Acids; Animals; Biological Transport; Cells, Cultured; Cystine; Dose-Response Relationship, Drug; Female; Glutamic Acid; Glutathione; Homocysteine; Interferon-gamma; Interleukin-1; Kinetics; Lipopolysaccharides; Macrophages, Peritoneal; Maleates; Mice; Mice, Inbred C57BL; Recombinant Proteins; Salmonella typhi; Serine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1995 |
A prominent role for glucosylglycerol in the adaptation of Pseudomonas mendocina SKB70 to osmotic stress.
Topics: Adaptation, Biological; Betaine; Dipeptides; Dose-Response Relationship, Drug; Glucosides; Glutamic Acid; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Osmotic Pressure; Pseudomonas; Sodium Chloride; Trehalose | 1994 |
Molecular and active-site structure of a Bacillus 1,3-1,4-beta-glucanase.
Topics: Amino Acid Sequence; Bacillus; Binding Sites; Carbohydrate Sequence; Epoxy Compounds; Glucans; Glucosides; Glutamates; Glutamic Acid; Glycoside Hydrolases; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; X-Ray Diffraction | 1993 |
Glu280 is the nucleophile in the active site of Clostridium thermocellum CelC, a family A endo-beta-1,4-glucanase.
Topics: Amino Acid Sequence; Binding Sites; Cellulase; Clostridium; Glucosides; Glutamates; Glutamic Acid; Kinetics; Mass Spectrometry; Molecular Sequence Data; Sequence Homology, Amino Acid | 1993 |
Sweet potato beta-amylase. Primary structure and identification of the active-site glutamyl residue.
Topics: Amino Acid Sequence; Amino Acids; beta-Amylase; Binding Sites; Chromatography, High Pressure Liquid; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Glucosides; Glutamates; Glutamic Acid; Molecular Sequence Data; Sequence Homology, Amino Acid; Serine Endopeptidases; Vegetables | 1993 |
Identification of two glutamic acid residues essential for catalysis in the beta-glycosidase from the thermoacidophilic archaeon Sulfolobus solfataricus.
Topics: Amino Acid Sequence; Binding Sites; Escherichia coli; Glucosidases; Glucosides; Glutamic Acid; Kinetics; Molecular Sequence Data; Mutation; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Stereoisomerism; Substrate Specificity; Sulfolobus | 1996 |
Identification of Glu-540 as the catalytic nucleophile of human beta-glucuronidase using electrospray mass spectrometry.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Catalytic Domain; Conserved Sequence; Glucosides; Glucuronidase; Glutamic Acid; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Models, Chemical; Peptide Fragments; Protein Conformation; Rats; Sequence Homology, Amino Acid | 1998 |
Restoration of the activity of active-site mutants of the hyperthermophilic beta-glycosidase from Sulfolobus solfataricus: dependence of the mechanism on the action of external nucleophiles.
Topics: Binding Sites; Catalytic Domain; Enzyme Activation; Formates; Glucosidases; Glucosides; Glutamic Acid; Glutamine; Glycine; Hot Temperature; Kinetics; Mutagenesis, Site-Directed; Sodium Azide; Sulfolobus | 1998 |
Monocytic cells secrete factors that evoke excitatory synaptic activity in rat hippocampal cultures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cell Death; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Fetus; Glutamic Acid; Hippocampus; Humans; Membrane Potentials; Monocytes; Neurons; Neurotoxins; Nimodipine; Patch-Clamp Techniques; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Tetrodotoxin; U937 Cells; Zymosan | 1999 |
Release of glutamate, nitric oxide and prostaglandin E2 and metabolic activity in the spinal cord of rats following peripheral nociceptive stimulation.
Topics: Animals; Dinoprostone; Glutamic Acid; Glycerol; Lactic Acid; Male; Microdialysis; Nitrates; Nitric Oxide; Nitrites; Nociceptors; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Zymosan | 2001 |
Synthesis and sensory characterization of novel umami-tasting glutamate glycoconjugates.
Topics: Flavoring Agents; Fructose; Glucosides; Glutamic Acid; Glycoconjugates; Humans; Magnetic Resonance Spectroscopy; Maillard Reaction; Molecular Structure; Sodium Glutamate; Solutions; Taste; Water | 2003 |
Glycosidation of cu,zn-superoxide dismutase with end-group aminated dextran: pharmacological and pharmacokinetics properties.
Topics: Amines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspartic Acid; Carbohydrate Sequence; Dextrans; Edema; Enzyme Activation; Foot Diseases; Glucosides; Glutamic Acid; Half-Life; Male; Molecular Sequence Data; Rats; Rats, Wistar; Superoxide Dismutase | 2005 |
The glutamate transporter GLAST is involved in spinal nociceptive processing.
Topics: Amino Acid Transport System X-AG; Animals; Formaldehyde; Glutamic Acid; Hyperalgesia; Male; Neurons; Oligonucleotides, Antisense; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Synaptic Transmission; Zymosan | 2006 |
A study of the neuroprotective effect of the phenolic glucoside gastrodin during cerebral ischemia in vivo and in vitro.
Topics: Animals; Benzyl Alcohols; Brain Ischemia; Cell Hypoxia; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Glutamic Acid; Hippocampus; Male; Neuroprotective Agents; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome | 2006 |
The protective effects of phenolic constituents from Gastrodia elata on the cytotoxicity induced by KCl and glutamate.
Topics: Adenosine; Animals; Antineoplastic Agents, Phytogenic; Benzyl Compounds; Cell Survival; Ethyl Ethers; Excitatory Amino Acid Antagonists; Gastrodia; Glucosides; Glutamic Acid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neuroprotective Agents; PC12 Cells; Phenols; Plant Extracts; Plant Tubers; Potassium Chloride; Rats; Tetrazolium Salts; Thiazoles | 2006 |
A microdialysis study of effects of gastrodin on neurochemical changes in the ischemic/reperfused rat cerebral hippocampus.
Topics: Animals; Benzyl Alcohols; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Hippocampus; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Ischemic Attack, Transient; Male; Microdialysis; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors | 2007 |
Protective effects of gastrodin on hypoxia-induced toxicity in primary cultures of rat cortical neurons.
Topics: Animals; Benzyl Alcohols; Brain Ischemia; Cell Hypoxia; Cerebral Cortex; Chromatography, High Pressure Liquid; Gastrodia; Glucosides; Glutamic Acid; Neuroprotective Agents; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome | 2007 |
Neuroprotective effects of emodin-8-O-beta-D-glucoside in vivo and in vitro.
Topics: Animals; Anthraquinones; Antioxidants; Behavior, Animal; Brain; Brain Chemistry; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Cerebral Infarction; Dose-Response Relationship, Drug; Fallopia japonica; Glucosides; Glutamic Acid; Male; Malondialdehyde; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase | 2007 |
Down-regulation of NR2B receptors partially contributes to analgesic effects of Gentiopicroside in persistent inflammatory pain.
Topics: Analgesics, Non-Narcotic; Animals; Blotting, Western; Chronic Disease; Cyclic AMP; Down-Regulation; Excitatory Postsynaptic Potentials; Freund's Adjuvant; Glucosides; Glutamic Acid; Inflammation; Iridoid Glucosides; Iridoids; Mice; Mice, Inbred C57BL; Pain; Pain Measurement; Patch-Clamp Techniques; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2008 |
Activation of microglia with zymosan promotes excitatory amino acid release via volume-regulated anion channels: the role of NADPH oxidases.
Topics: Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Encephalitis; Enzyme Inhibitors; Excitatory Amino Acids; Glutamic Acid; Isoenzymes; Microglia; NADPH Oxidase 4; NADPH Oxidases; Oxidants; Oxidative Stress; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Voltage-Dependent Anion Channels; Zymosan | 2008 |
Salidroside attenuates glutamate-induced apoptotic cell death in primary cultured hippocampal neurons of rats.
Topics: Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Embryo, Mammalian; Flow Cytometry; Glucosides; Glutamic Acid; Hippocampus; In Situ Nick-End Labeling; Neurons; Neuroprotective Agents; Phenols; Rats; Rats, Sprague-Dawley | 2008 |
Analgesic effect of paeoniflorin in rats with neonatal maternal separation-induced visceral hyperalgesia is mediated through adenosine A(1) receptor by inhibiting the extracellular signal-regulated protein kinase (ERK) pathway.
Topics: Adenosine A1 Receptor Antagonists; Analgesics; Animals; Animals, Newborn; Benzoates; Brain; Bridged-Ring Compounds; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; Glucosides; Glutamic Acid; Hyperalgesia; Male; MAP Kinase Signaling System; Maternal Deprivation; Mitogen-Activated Protein Kinase Kinases; Monoterpenes; Paeonia; Pain Threshold; Phosphorylation; Proto-Oncogene Proteins c-fos; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Reflex, Abdominal; Viscera | 2009 |
Neuroprotective effect of 5,7,3',4',5'-pentahydroxy dihydroflavanol-3-O-(2''-O-galloyl)-beta-D-glucopyranoside, a polyphenolic compound in focal cerebral ischemia in rat.
Topics: Animals; Antioxidants; Apoptosis; Behavior, Animal; Brain Edema; Brain Ischemia; Cerebral Infarction; Flavonoids; Glucosides; Glutamic Acid; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Oxidative Stress; Phenols; Polyphenols; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Time Factors | 2010 |
Protective effects of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via antioxidant mechanisms and Ca(2+) antagonism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antioxidants; Benzoates; Bridged-Ring Compounds; Calbindin 1; Calbindins; Calcium; Cell Survival; Glucosides; Glutamic Acid; Humans; Malondialdehyde; Molecular Structure; Monoterpenes; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; S100 Calcium Binding Protein G; Superoxide Dismutase | 2010 |
[Effect of polydatin on dynamic changes of excitatory amino acids in cerebrospinal fluid of cerebral hemorrhage rats].
Topics: Animals; Aspartic Acid; Cerebral Hemorrhage; Disease Models, Animal; Drugs, Chinese Herbal; Excitatory Amino Acids; Glucosides; Glutamic Acid; Humans; Male; Rats; Rats, Sprague-Dawley; Stilbenes | 2010 |
Rhodiola rosea extract protects human cortical neurons against glutamate and hydrogen peroxide-induced cell death through reduction in the accumulation of intracellular calcium.
Topics: Antioxidants; Calcium; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Survival; Glucosides; Glutamic Acid; Homeostasis; Humans; Hydrogen Peroxide; Neurons; Neuroprotective Agents; Oxidative Stress; Phenols; Plant Extracts; Rhizome; Rhodiola | 2012 |
QM/MM investigation on the catalytic mechanism of Bacteroides thetaiotaomicron α-glucosidase BtGH97a.
Topics: alpha-Glucosidases; Bacterial Proteins; Bacteroides; Biocatalysis; Catalytic Domain; Glucosides; Glutamic Acid; Hydrolysis; Kinetics; Molecular Docking Simulation; Oxygen; Protons; Quantum Theory; Thermodynamics; Water | 2012 |
Free glucosylglycerate is a novel marker of nitrogen stress in Mycobacterium smegmatis.
Topics: Biomarkers; Glucosides; Glutamic Acid; Glyceric Acids; Ketoglutaric Acids; Mycobacterium smegmatis; Nitrogen; Stress, Physiological; Trehalose | 2012 |
Gastrodin improved baroreflex sensitivity and increased gamma-amino butyric acid content in brains without decreasing blood pressure in spontaneously hypertensive rats.
Topics: Animals; Baroreflex; Benzyl Alcohols; Blood Pressure; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Mass Spectrometry; Rats; Rats, Inbred SHR | 2012 |
Anticonvulsive effect of paeoniflorin on experimental febrile seizures in immature rats: possible application for febrile seizures in children.
Topics: Animals; Anticonvulsants; Benzoates; Bridged-Ring Compounds; Calcium; Cells, Cultured; Child; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Hippocampus; Humans; Male; Monoterpenes; Neurons; Rats; Seizures, Febrile | 2012 |
Protective effect of paeoniflorin against glutamate-induced neurotoxicity in PC12 cells via Bcl-2/Bax signal pathway.
Topics: Animals; bcl-2-Associated X Protein; Benzoates; Bridged-Ring Compounds; Cell Survival; Glucosides; Glutamic Acid; Monoterpenes; Neuroprotective Agents; Paeonia; PC12 Cells; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction | 2012 |
Anti-hyperalgesic activity of corilagin, a tannin isolated from Phyllanthus niruri L. (Euphorbiaceae).
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Capsaicin; Formaldehyde; Glucosides; Glutamic Acid; Hot Temperature; Hydrolyzable Tannins; Hyperalgesia; Male; Mice; Motor Activity; Phyllanthus; Phytotherapy | 2013 |
Neuroprotective effects of paeoniflorin: an emerging concept in neurology.
Topics: Animals; bcl-2-Associated X Protein; Benzoates; Bridged-Ring Compounds; Glucosides; Glutamic Acid; Neuroprotective Agents; Paeonia; Proto-Oncogene Proteins c-bcl-2 | 2013 |
Neuroprotective effects of paeoniflorin, but not the isomer albiflorin, are associated with the suppression of intracellular calcium and calcium/calmodulin protein kinase II in PC12 cells.
Topics: Animals; Apoptosis; Benzoates; Bridged-Ring Compounds; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Survival; Cytoplasm; Glucosides; Glutamic Acid; Monoterpenes; Neuroprotective Agents; PC12 Cells; Protein Kinase Inhibitors; Rats; Reactive Oxygen Species | 2013 |
Anticonvulsant and sedative effects of paederosidic acid isolated from Paederia scandens (Lour.) Merrill. in mice and rats.
Topics: Animals; Anticonvulsants; Blotting, Western; Brain; gamma-Aminobutyric Acid; Glucosides; Glutamate Decarboxylase; Glutamic Acid; Heterocyclic Compounds, 2-Ring; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Plant Extracts; Rats; Rats, Sprague-Dawley; Rubiaceae | 2013 |
Transglycosylation of engineered cyclodextrin glucanotransferases as O-glycoligases.
Topics: Alanine; Escherichia coli; Gene Expression; Glucosides; Glucosyltransferases; Glutamic Acid; Glycosylation; Kinetics; Ligases; Mutagenesis, Site-Directed; Mutation; Protein Engineering; Serine | 2014 |
Gastrodin inhibits glutamate-induced apoptosis of PC12 cells via inhibition of CaMKII/ASK-1/p38 MAPK/p53 signaling cascade.
Topics: Animals; Apoptosis; Benzyl Alcohols; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Survival; Cytochromes c; Glucosides; Glutamic Acid; MAP Kinase Kinase Kinase 5; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Rats; Signal Transduction; Tumor Suppressor Protein p53 | 2014 |
MADP, a salidroside analog, protects hippocampal neurons from glutamate induced apoptosis.
Topics: Acetylglucosamine; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Cells, Cultured; Flow Cytometry; Glucosides; Glutamic Acid; Hippocampus; In Situ Nick-End Labeling; Mitogen-Activated Protein Kinases; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Phenols; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Liquiritin modulates ERK‑ and AKT/GSK‑3β‑dependent pathways to protect against glutamate‑induced cell damage in differentiated PC12 cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cytochromes c; Extracellular Signal-Regulated MAP Kinases; Flavanones; Flavonoids; Glucosides; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Membrane Potential, Mitochondrial; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction | 2014 |
Salidroside protects cortical neurons against glutamate-induced cytotoxicity by inhibiting autophagy.
Topics: Animals; Autophagy; Cell Survival; Cerebral Cortex; Glucosides; Glutamic Acid; Nerve Tissue Proteins; Neurons; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction | 2016 |
Neuroprotective effects of 2,3,5,4'-tetrahydoxystilbene-2-O-β-D-glucoside from Polygonum multiflorum against glutamate-induced oxidative toxicity in HT22 cells.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Fallopia multiflora; Glucosides; Glutamic Acid; Hippocampus; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neurons; Neuroprotective Agents; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Reactive Oxygen Species; Stilbenes; Voltage-Dependent Anion Channel 1 | 2017 |
Chemical basis for the disparate neuroprotective effects of the anthocyanins, callistephin and kuromanin, against nitrosative stress.
Topics: Animals; Anthocyanins; Cells, Cultured; Drug Evaluation, Preclinical; Fragaria; Glucosides; Glutamic Acid; Neurons; Neuroprotective Agents; Nitric Oxide; Nitrosative Stress; Plant Extracts; Rats, Sprague-Dawley; Rubus; Signal Transduction; Superoxides | 2017 |
Paeoniflorin exerts neuroprotective effects against glutamate‑induced PC12 cellular cytotoxicity by inhibiting apoptosis.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cytotoxins; Gene Expression Regulation; Glucosides; Glutamic Acid; Monoterpenes; Neuroprotective Agents; PC12 Cells; Rats | 2017 |
Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect.
Topics: Alanine; Benzhydryl Compounds; Canagliflozin; Cell Death; Cell Line; Citric Acid Cycle; Electron Transport Complex I; Epithelial Cells; Glucosides; Glutamate Dehydrogenase; Glutamic Acid; Glutamine; Humans; Hypoglycemic Agents; Kidney Tubules, Proximal; Metabolomics; Mitochondria | 2018 |
Effect of Gastrodin on Early Brain Injury and Neurological Outcome After Subarachnoid Hemorrhage in Rats.
Topics: Animals; Apoptosis; Astrocytes; Benzyl Alcohols; Blood-Brain Barrier; Brain; Brain Edema; Calcium; Glucosides; Glutamic Acid; Male; Microglia; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Subarachnoid Hemorrhage | 2019 |
Early intervention with gastrodin reduces striatal neurotoxicity in adult rats with experimentally‑induced diabetes mellitus.
Topics: Animals; Benzyl Alcohols; Biomarkers; Brain-Derived Neurotrophic Factor; Corpus Striatum; Diabetes Mellitus, Experimental; Gene Expression; Glucosides; Glutamic Acid; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Neurons; Rats; Receptor, trkB | 2019 |
Gastrodin alleviates Tourette syndrome via Nrf-2/HO-1/HMGB1/NF-кB pathway.
Topics: Animals; Benzyl Alcohols; Corpus Striatum; Cytokines; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Heme Oxygenase-1; HMGB1 Protein; Male; Malondialdehyde; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tourette Syndrome | 2019 |
Gastrodin protects against glutamate-induced ferroptosis in HT-22 cells through Nrf2/HO-1 signaling pathway.
Topics: Animals; Benzyl Alcohols; Cell Line; Ferroptosis; Gastrodia; Glucosides; Glutamic Acid; Heme Oxygenase-1; L-Lactate Dehydrogenase; Lipid Peroxidation; Membrane Proteins; Mice; Neurons; NF-E2-Related Factor 2; Protective Agents; Reactive Oxygen Species; Signal Transduction; Translocation, Genetic | 2020 |
Cyanidin-3-glucoside activates Nrf2-antioxidant response element and protects against glutamate-induced oxidative and endoplasmic reticulum stress in HT22 hippocampal neuronal cells.
Topics: Animals; Anthocyanins; Antioxidants; Cell Line; Endoplasmic Reticulum Stress; Flow Cytometry; Glucosides; Glutamic Acid; Hippocampus; Mice; Molecular Structure; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Plant Extracts | 2020 |
Anxiolytic Effects of 8-O-Acetyl Shanzhiside Methylester on Acute and Chronic Anxiety via Inflammatory Response Inhibition and Excitatory/Inhibitory Transmission Imbalance.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anxiety; Chronic Disease; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Freund's Adjuvant; gamma-Aminobutyric Acid; Glucosides; Glutamic Acid; Inflammation Mediators; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Pyrans | 2020 |
Paeoniflorin ameliorates oxidase stress in Glutamate-stimulated SY5Y and prenatally stressed female offspring through Nrf2/HO-1 signaling pathway.
Topics: Animals; Apoptosis; Female; Glucosides; Glutamic Acid; Heme Oxygenase (Decyclizing); Monoterpenes; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Oxidoreductases; Pregnancy; Rats; Signal Transduction | 2021 |
Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state.
Topics: Allosteric Regulation; Allosteric Site; Amino Acids; Biphenyl Compounds; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Cell Membrane; Cholesterol Esters; Diosgenin; Disaccharides; Fluorescence Resonance Energy Transfer; Gene Expression; Glucosides; Glutamic Acid; Glycolipids; HEK293 Cells; Humans; Indans; Micelles; Octoxynol; Protein Binding; Protein Conformation; Protein Multimerization; Receptors, Metabotropic Glutamate; Recombinant Proteins; Single Molecule Imaging; Xanthenes | 2021 |
Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
Topics: Amyotrophic Lateral Sclerosis; Animals; Axons; Benzyl Alcohols; Calcium; Cell Differentiation; Glucosides; Glutamic Acid; Glycogen Synthase Kinase 3 beta; Humans; Induced Pluripotent Stem Cells; Insulin-Like Growth Factor I; MAP Kinase Signaling System; Mice, Transgenic; Motor Neurons; Mutation; Nerve Degeneration; Nerve Fibers; Neurites; Superoxide Dismutase-1; Survival Analysis | 2021 |